Taking Pills Quotes

Listen to the people who love you. Believe that they are worth living for even when you don't believe it. Seek out the memories depression takes away and project them into the future. Be brave; be strong; take your pills. Exercise because it's good for you even if every step weighs a thousand pounds. Eat when food itself disgusts you. Reason with yourself when you have lost your reason.

You’re in a car with a beautiful boy, and he won’t tell you that he loves you, but he loves you. And you feel like you’ve done something terrible, like robbed a liquor store, or swallowed pills, or shoveled yourself a grave in the dirt, and you’re tired. You’re in a car with a beautiful boy, and you’re trying not to tell him that you love him, and you’re trying to choke down the feeling, and you’re trembling, but he reaches over and he touches you, like a prayer for which no words exist, and you feel your heart taking root in your body, like you’ve discovered something you didn’t even have a name for.

All right," said Susan. "I'm not stupid. You're saying humans need... fantasies to make life bearable." REALLY? AS IF IT WAS SOME KIND OF PINK PILL? NO. HUMANS NEED FANTASY TO BE HUMAN. TO BE THE PLACE WHERE THE FALLING ANGEL MEETS THE RISING APE. "Tooth fairies? Hogfathers? Little—" YES. AS PRACTICE. YOU HAVE TO START OUT LEARNING TO BELIEVE THE LITTLE LIES. "So we can believe the big ones?" YES. JUSTICE. MERCY. DUTY. THAT SORT OF THING. "They're not the same at all!" YOU THINK SO? THEN TAKE THE UNIVERSE AND GRIND IT DOWN TO THE FINEST POWDER AND SIEVE IT THROUGH THE FINEST SIEVE AND THEN SHOW ME ONE ATOM OF JUSTICE, ONE MOLECULE OF MERCY. AND YET—Death waved a hand. AND YET YOU ACT AS IF THERE IS SOME IDEAL ORDER IN THE WORLD, AS IF THERE IS SOME...SOME RIGHTNESS IN THE UNIVERSE BY WHICH IT MAY BE JUDGED. "Yes, but people have got to believe that, or what's the point—" MY POINT EXACTLY.

Never, under any circumstances, take a sleeping pill and a laxative on the same night.

I want to go to sleep and not wake up, but I don't want to die. I want to eat like a normal person eats, but I need to see my bones or I will hate myself even more and I might cut my heart out or take every pill that was ever made.

sometimes we take chances, sometimes we take pills.

No one ever tells us to stop running away from fear...the advice we usually get is to sweeten it up, smooth it over, take a pill, or distract ourselves, but by all means make it go away. (5)

We throw our parties; we abandon our families to live alone in Canada; we struggle to write books that do not change the world, despite our gifts and our unstinting efforts, our most extravagant hopes. We live our lives, do whatever we do, and then we sleep. It's as simple and ordinary as that. A few jump out windows, or drown themselves, or take pills; more die by accident; and most of us are slowly devoured by some disease, or, if we're very fortunate, by time itself. There's just this for consolation: an hour here or there when our lives seem, against all odds and expectations, to burst open and give us everything we've ever imagined, though everyone but children (and perhaps even they) know these hours will inevitably be followed by others, far darker and more difficult. Still, we cherish the city, the morning; we hope, more than anything, for more. Heaven only knows why we love it so...

I had to stop myself from laughing. Who needs help taking a pill?

No pill can help me deal with the problem of not wanting to take pills; likewise, no amount of psychotherapy alone can prevent my manias and depressions. I need both. It is an odd thing, owing life to pills, one's own quirks and tenacities, and this unique, strange, and ultimately profound relationship called psychotherapy

The Pill Versus the Springhill Mine Disaster When you take your pill it's like a mine disaster. I think of all the people lost inside you.

It's an odd thing to think about, but try imagining that your breakup is a disease. If you were told that you had a serious yet curable disease, would you go get hammered on a regular basis? Eat two bags of Oreos? Chain-smoke, pop, pills, get stoned, or fuck around? NO YOU WOULDN'T. You would take great care of yourself and cut all the unhealthy things out of your life. Because you love yourself, and even if you don't right now, WE DO. So put the (insert vice here) and start moving on.

You're sad because you're sad. It's psychic. It's the age. It's chemical. Go see a shrink or take a pill, or hug your sadness like an eyeless doll you need to sleep. Well, all children are sad but some get over it. Count your blessings. Better than that, buy a hat. Buy a coat or a pet. Take up dancing to forget.

It's a good thing you and your pills weren't around a few hundred years ago or there never would have been a Vermeer or a Caravaggio. You'd have drugged "Girl with a Pearl Earring" and "The Taking of Christ" right the hell out of them.

We should leave people alone about their weight. Being skinny for a while (provided you actually eat food and don't take pills or smoke to get there) is a perfectly fine pastime. Everyone should try it once, like a super-short haircut or dating a white guy.

If taking a pill makes you different, like, if it changes the way-down you . . . that's just a screwed up idea, you know? Who's deciding what me means--me or the employees of the factory that make Lexapro?

If you're strong enough to take that blade and draw it across your skin. If you're strong enough to take those pills and swallow them when no one's home. If you're strong enough to tie that rope and hang it from the ceiling fan. If you're strong enough to jump off the bridge, my friend. You are strong enough to live.

I want to eat like a normal person eats, but I need to see my bones or I will hate myself even more and I might cut out my heart or take every pill that was ever made.

Whatever it is," I said, "the point is moot because as long as I'm on these pills, I can't make contact to ask." Derek ... snapped, "Then you need to stop taking the pills." Love to. If I could. But after what happened last night, they're giving me urine tests now." Ugh. That's harsh." Simon went quiet, then snapped his fingers. Hey, I've got an idea. It's kinda gross, but what if you take the pills, crush them and mix them with your, you know, urine." Derek stared at him. What?" You did pass chem last year, didn't you?" Simon flipped him the finger. "Okay, genius, what's your idea?" I'll think about it. ..." *** Here," Derek whispered, pressing an empty Mason jar into my hand. He'd pulled me aside after class and we were now standing at the base of the boy's staircase. "Take this up to your room and hide it." It's a ... jar." He grunted, exasperated that I was so dense I failed to see the critical importance of hiding an empty Mason jar in my room. It's for your urine." My what?" He rolled his eyes, a growl-like sound sliding through his teeth as he leaned down, closer to my ear. "Urine. Pee. Whatever. For the testing." I lifted the jar to eye level. "I think they'll give me something smaller." ... You took your meds today, right?" he whispered. I nodded. Then use this jar to save it." Save . . . ?" Your urine. If you give them some of today's tomorrow, it'll seem like you're still taking your meds." You want me to . . . dole it out? Into specimen jars?" Got a better idea?" Um, no, but ..." I lifted the jar and stared into it. Oh, for God's sake. Save your piss. Don't save your piss. It's all the same to me." Simon peeked around the corner, brows lifted. "I was going to ask what you guys were doing, but hearing that, I think I'll pass.

When I see a couple of kids And guess he's fucking her and she's Taking pills or wearing a diaphragm, I know this is paradise Everyone old has dreamed of all their lives— Bonds and gestures pushed to one side Like an outdated combine harvester, And everyone young going down the long slide

Love is not enough. It takes courage to grab my father's demon, my own, or - God help me - my child's and strap it down and stop its mad jig; to sit in a row of white rooms filled with pills and clubbed dreamers and shout: stop smiling, shut up; shut up and stop laughing; you're sitting in hell. Stop preaching; stop weeping. You are a manic-depressive, always. your life is larger than most, unimaginable. You're blessed; just admit it and take the damn pill.

Anxious, depressed, psychotic, lunatic, bipolar, manic - you name it, I attract it. Perhaps you’ve heard of me? In some circles I am known as the Pied Piper of Mental Illness.

I can’t function here anymore. I mean in life: I can’t function in this life. I’m no better off than when I was in bed last night, with one difference: when I was in my own bed—or my mom’s—I could do something about it; now that I’m here I can’t do anything. I can’t ride my bike to the Brooklyn Bridge; I can’t take a whole bunch of pills and go for the good sleep; the only thing I can do is crush my head in the toilet seat, and I still don’t even know if that would work. They take away your options and all you can do is live, and it’s just like Humble said: I’m not afraid of dying; I’m afraid of living. I was afraid before, but I’m afraid even more now that I’m a public joke. The teachers are going to hear from the students. They’ll think I’m trying to make an excuse for bad work.

A moth goes into a podiatrist’s office, and the podiatrist’s office says, “What seems to be the problem, moth?” The moth says “What’s the problem? Where do I begin, man? I go to work for Gregory Illinivich, and all day long I work. Honestly doc, I don’t even know what I’m doing anymore. I don’t even know if Gregory Illinivich knows. He only knows that he has power over me, and that seems to bring him happiness. But I don’t know, I wake up in a malaise, and I walk here and there… at night I…I sometimes wake up and I turn to some old lady in my bed that’s on my arm. A lady that I once loved, doc. I don’t know where to turn to. My youngest, Alexendria, she fell in the…in the cold of last year. The cold took her down, as it did many of us. And my other boy, and this is the hardest pill to swallow, doc. My other boy, Gregarro Ivinalititavitch… I no longer love him. As much as it pains me to say, when I look in his eyes, all I see is the same cowardice that I… that I catch when I take a glimpse of my own face in the mirror. If only I wasn’t such a coward, then perhaps…perhaps I could bring myself to reach over to that cocked and loaded gun that lays on the bedside behind me and end this hellish facade once and for all…Doc, sometimes I feel like a spider, even though I’m a moth, just barely hanging on to my web with an everlasting fire underneath me. I’m not feeling good. And so the doctor says, “Moth, man, you’re troubled. But you should be seeing a psychiatrist. Why on earth did you come here?” And the moth says, “‘Cause the light was on.

We live our lives, do whatever we do, and then we sleep - it's as simple and ordinary as that. A few jump out of windows or drown themselves or take pills; more die by accident; and most of us, the vast majority, are slowly devoured by some disease or, if we're very fortunate, by time itself. There's just this for consolation: an hour here or there when our lives seem, against all odds and expectations, to burst open and give us everything we've ever imagined, though everyone but children (and perhaps even they) knows these hours will inevitably be followed by others, far darker and more difficult. Still, we cherish the city, the morning; we hope, more than anything, for more.

In light of my distanced telescopic exposure to the mayhem, I refused to plagiarise others’ personal tragedies as my own. There is an authorship in misery that costs more than empathy. Often I’d found myself dumbstruck in failed attempts to simulate that particular unfamiliar dolour. After all, no one takes pleasure in being possessed by a wailing father collecting the decapitated head of his innocent six year old. Even on the hinge of a willing attempt at full empathy with those cursed with such catastrophes, one had to have a superhuman emotional powers. I could not, in any way, claim the ability to relate to those who have been forced to swallow the never-ending bitter and poisonous pills of our inherited misfortune. Yet that excruciating pain in my chest seemed to elicit a state of agony in me, even from far behind the telescope. It could have been my tribal gene amplified by the ripple effect of the falling, moving in me what was left of my humanity.

It's a really crappy feeling to realize that your entire outook on your life can be controlled by some little pill that looks like a Pez, and that some weird combination of drugs can make your brain think it's on a holiday somewhere really sweet when you're standing naked in the middle of the school cafeteria while everyone takes pictures of you. Metaphorically. Or whatever.

The traveling salesmen fed me pills that made the lining of my veins feel scraped out, my jaw ached... I knew every raindrop by its name, I sensed everything before it happened. Like I knew a certain oldsmobile would stop even before it slowed, and by the sweet voices of the family inside, I knew we'd have an accident in the rain. I didn't care. They said they'd take me all the way.

I am fearful of romantic dinners, huge crowds, dusk - of normal things- afraid to be loved, the one thing I want most. Maybe it's because I don't think I deserve it because I am not that perfect little girl that I was supposed to be, well manicured and well groomed, because I have nervous breakdowns, and take pills, and keep moving on.

When I get home I take some sleeping pills and within what seemed like half an hour of unconsciousness it was Monday morning again.

I balked at trying antidepressants, I just couldn't see myself taking pills to try to be less of a fraud.

If you want your customers to start eating spinach flavored ice cream, your idea won’t need as much cultural change as it will if you want your customers to start taking a coffee pill in the morning instead of fresh brewed coffee. Obviously, the latter will require more efforts and more marketing.

People who aren't asleep when Ruby comes around have to take sleeping pills. Everyone is afraid of those pills- even the substance- abuse guests.

Happiness consists in getting enough sleep. Just that, nothing more. All the wealthy, unhappy people you're ever met take sleeping pills; Mobile Infantrymen don't need them. Give a cap trooper a bunk and time to sack out in it and he's as happy as a worm in an apple - asleep.

You take the blue pill, the story ends, you wake up in your bed and believe whatever you want to believe. You take the red pill, you stay in Wonderland, and I show you how deep the rabbit hole goes.

We live our lives, do whatever we do, and then we sleep. It's as simple and ordinary as that. A few jump out windows, or drown themselves, or take pills; more die by accident; and most of us are slowly devoured by some disease, or, if we're very fortunate, by time itself. There's just this for consolation: an hour here or there when our lives seem, against all odds & expectations, to burst open & give us everything we've ever imagined, though everyone but children (and perhaps even they) know these hours will inevitably be followed by others, far darker and more difficult. Still, we cherish the city, the morning, we hope, more than anything for more. Heaven only knows why we love it so.

We’re all running from pain. Some of us take pills. Some of us couch surf while binge-watching Netflix. Some of us read romance novels. We’ll do almost anything to distract ourselves from ourselves. Yet all this trying to insulate ourselves from pain seems only to have made our pain worse.

There are many ways to understand this. One simple way to know this is: today, if you lose your mental peace totally, you will go to a doctor. He will give you a pill. If you take this pill, your system will become peaceful. Maybe this will last just for a few hours, but you become peaceful. This pill is just a little bit of chemicals. These chemicals enter your system and make you peaceful. Or in other words, what you call peace is a certain kind of chemistry within you. Similarly, what you call joy, what you call love, what you call suffering, what you call misery, what you call fear, every human experience that you go through, has a chemical basis within you. Now the spiritual process is just to create the right kind of chemistry, where you are naturally peaceful, naturally joyous. When you are joyous by your own nature, when you don’t have to do anything to be happy, then the very dimension of your life, the very way you perceive and express yourself in the world will change. The very way you experience your life will change.

It is not depression or anxiety that truly hurts us. It is our active resistance against these states of mind and body. If you wake up with low energy, hopeless thoughts, and a lack of motivation - that is a signal from you to you. That is a sure sign that something in your mind or in your life is making you sick, and you must attend to that signal. But what do most people do? They hate their depressed feelings. They think "Why me?" They push them down. They take a pill. And so, the feelings return again and again, knocking at your door with a message while you turn up all the noise in your cave, refusing to hear the knocks. Madness. Open the door. Invite in depression. Invite anxiety. Invite self-hatred. Invite shame. Hear their message. Give them a hug. Accept their tirades as exaggerated mistruths typical of any upset person. Love your darkness and you shall know your light.

Chess lied to herself every day; it was just something she did, like taking her pills or making sure she had a pen in her bag. Little lies, mostly. Insignificant. Of course there were big ones there, too, like telling herself that she was more than just a junkie who got lucky enough to possess a talent not everyone had. That she was alone by choice and that she was not terrified of other people because they couldn’t be trusted, because they carried filth in their minds and pain in their hands and they would smear both all over her given half the chance.

Why do I take a blade and slash my arms? Why do I drink myself into a stupor? Why do I swallow bottles of pills and end up in A&E having my stomach pumped? Am I seeking attention? Showing off? The pain of the cuts releases the mental pain of the memories, but the pain of healing lasts weeks. After every self-harming or overdosing incident I run the risk of being sectioned and returned to a psychiatric institution, a harrowing prospect I would not recommend to anyone. So, why do I do it? I don't. If I had power over the alters, I'd stop them. I don't have that power. When they are out, they're out. I experience blank spells and lose time, consciousness, dignity. If I, Alice Jamieson, wanted attention, I would have completed my PhD and started to climb the academic career ladder. Flaunting the label 'doctor' is more attention-grabbing that lying drained of hope in hospital with steri-strips up your arms and the vile taste of liquid charcoal absorbing the chemicals in your stomach. In most things we do, we anticipate some reward or payment. We study for status and to get better jobs; we work for money; our children are little mirrors of our social standing; the charity donation and trip to Oxfam make us feel good. Every kindness carries the potential gift of a responding kindness: you reap what you sow. There is no advantage in my harming myself; no reason for me to invent delusional memories of incest and ritual abuse. There is nothing to be gained in an A&E department.

All I meant was that people take their same old lives wherever they go. No place is perfect enough to strip you of that. And some places have a way of magnifying your demons, or of, I don't know, giving them pep pills.

I've been accustomed to mysteries, holy and otherwise, since I was a child. Some of us care for orphans, amass fortunes, raise protests or Nielsen ratings; some of us take communion or whiskey or poison. Some of us take lithium and antidepressants, and most everyone believes these pills are fundamentally wrong, a crutch, a sign of moral weakness, the surrender of art and individuality. Bullshit. Such thinking guarantees tradgedy for the bipolar. Without medicine, 20 percent of us, one in five, will commit suicide. Six-gun Russian roulette gives better odds. Denouncing these medicines makes as much sense as denouncing the immorality of motor oil. Without them, sooner or later the bipolar brain will go bang. I know plenty of potheads who sermonize against the pharmaceutical companies; I know plenty of born-again yoga instructors, plenty of missionaries who tell me I'm wrong about lithium. They don't have a clue.

A man walks into a bar and says: Take my wife–please. So you do. You take her out into the rain and you fall in love with her and she leaves you and you’re desolate. You’re on your back in your undershirt, a broken man on an ugly bedspread, staring at the water stains on the ceiling. And you can hear the man in the apartment above you taking off his shoes. You hear the first boot hit the floor and you’re looking up, you’re waiting because you thought it would follow, you thought there would be some logic, perhaps, something to pull it all together but here we are in the weeds again, here we are in the bowels of the thing: your world doesn’t make sense. And then the second boot falls. And then a third, a fourth, a fifth. A man walks into a bar and says: Take my wife–please. But you take him instead. You take him home, and you make him a cheese sandwich, and you try to get his shoes off, but he kicks you and he keeps kicking you. You swallow a bottle of sleeping pills but they don’t work. Boots continue to fall to the floor in the apartment above you. You go to work the next day pretending nothing happened. Your co-workers ask if everything’s okay and you tell them you’re just tired. And you’re trying to smile. And they’re trying to smile. A man walks into a bar, you this time, and says: Make it a double. A man walks into a bar, you this time, and says: Walk a mile in my shoes. A man walks into a convenience store, still you, saying: I only wanted something simple, something generic… But the clerk tells you to buy something or get out. A man takes his sadness down to the river and throws it in the river but then he’s still left with the river. A man takes his sadness and throws it away but then he’s still left with his hands.

Roger that. So go fuck your bullshit shoulders,” he says. “Whatever you got going on, someone else has more pain. You gotta learn how to fight through it. No matter what it is… Think about someone else and take a suck-shit pill.

One of the side effects of Viagra is blurred vision. Sounds great! When I’m taking a pill to pop a stiffy, how great is it that any woman I look at has blurred features and therefore is as beautiful as an impressionistic painting?


Lemme take your picture! You fucking bok gwai low got a face carved out of rotten potato cured in dogshit, runover with a towtruck driven by Hellen Keller in a puke fit on pills...

Everyone would die but me,” she said. “They’d all take pills and die. They’ll do it right away so they don’t use up any food. Commander Lewis picked me to be the survivor. She told me about it yesterday. I don’t think NASA knows about it.

This is your last chance. After this, there is no turning back. You take the blue pill – the story ends, you wake up in your bed and believe whatever you want to believe. You take the red pill – you stay in Wonderland, and I show you how deep the rabbit hole goes. Remember, all I'm offering is the truth – nothing more.

Take a stress pill and think things over-- HAL in 2001

Grief is an impossible meal, so we cut it up into little pieces, dress it in ritual, and take it like a pill.

Is This Happiness" High up in the Hollywood Hills taking violet pills Writing all of my songs about my cheap thrills You're a hard man to love and I'm A hard woman to keep track of You like to rage, don't do that You want your way, you make me so mad Got your gun, I've got my dad Is this happiness? Is this happiness? Is this happiness? Is this happiness? High up in the Hollywood Hills crushing violet pills You've been trying to write a novel about your cheap thrills You think you're Hunter S. Thompson I think you're fucking crazy as the day's long Man to man, heart to heart I love you but you drive me so far Wish you well on that star Is this happiness? Is this happiness? Is this happiness? Is this happiness? Witch Hazel, Witch Hazel Betrayal, betrayal One gun on the table Headshot if you're able Is this happiness? Is this happiness? Is this happiness? Is this happiness?

I've got to that point in life when there's very few thrills and lots of pills seems we all end up this way. As we wait for our final day. But there's one thing about the pills I take. My manic episodes have taken a break

Did you have one of those days today, like a nail in the foot? Did the pterodactyl corpse dropped by the ghost of your mother from the spectral Hindenburg forever circling the Earth come smashing through the lid of your glass coffin? Did the New York strip steak you attacked at dinner suddenly show a mouth filled with needle-sharp teeth, and did it snap off the end of your fork, the last solid-gold fork from the set Anastasia pressed into your hands as they took her away to be shot? Is the slab under your apartment building moaning that it cannot stand the weight on its back a moment longer, and is the building stretching and creaking? Did a good friend betray you today, or did that good friend merely keep silent and fail to come to your aid? Are you holding the razor at your throat this very instant? Take heart, comfort is at hand. This is the hour that stretches. Djan karet. We are the cavalry. We're here. Put away the pills. We'll get you through this bloody night. Next time, it'll be your turn to help us. "Eidolons" (1988)

We throw our parties; we abandon our families to live alone in Canada; we struggle to write books that do not change the world, despite our gifts and our unstinting efforts, our most extravagant hopes. We live our lives, do whatever we do, and then we sleep--it's as simple and ordinary as that. A few jump out of windows or drown themselves or take pills; more die by accident; and most of us, the vast majority, are slowly devoured by some disease or, if we're very fortunate, by time itself.

If at eighty you're not a cripple or an invalid, if you have your health, if you still enjoy a good walk, a good meal (with all the trimmings), if you can sleep without first taking a pill, if birds and flowers, mountains and sea still inspire you, you are a most fortunate individual and you should get down on your knees morning and night and thank the good Lord for his savin' and keepin' power. If you are young in years but already weary in spirit, already on your way to becoming an automaton, it may do you good to say to your boss - under your breath, of course - "Fuck you, Jack! you don't own me." If you can whistle up your ass, if you can be turned on by a fetching bottom or a lovely pair of teats, if you can fall in love again and again, if you can forgive your parents for the crime of bringing you into the world, if you are content to get nowhere, just take each day as it comes, if you can forgive as well as forget, if you can keep from going sour, surly, bitter and cynical, man you've got it half licked.

A seemingly simple task like taking a bath or wearing a condom feels like multitasking to someone who suffers from hemiplegia or has only one hand.

Mummy and Daddy want him to be an evil genius, but he has his heart set on Latin verse. Don’t you, Pill?” The boy gave his sister a nasty stare. “Pillover is terribly bad at being bad, if you take my meaning. Our daddy is a founding member of the Death Weasel Confederacy, and Mummy is a kitchen chemist with questionable intent, but poor Pillover can’t even bring himself to murder ants with his Depraved Lens of Crispy Magnification. Can you, Pill?

She should know how good I am at pretending. It's all we do. I pretend that I don't hurt, that I want Cody, that I don't want her, that I'm not taking too many pills, that my virginity had been important. It hadn't been. It only means something when it's with the right person. And I couldn't have her.

He died taking mercury pills that he thought would make him immortal," Tang Taizong said. "So did you!" Qin Sho Haung yelped without looking at him. "Allegedly! Sources differ!" "You know what you did!

I was not taking [my prescription] quite as often as I was technically supposed to. Partly, I kept forgetting, but also there was something else I couldn't quite identify, some way-down fear that taking a pill to become myself was wrong.

I guess that sometimes it just takes a long walk through the darkness, a long walk through the darkest shadows and corners of your soul to realize that those are a part of you as well, that you've created through your experiences and thoughts those parts within yourself and as much as you can choose to fear them and repress them, they will require your attention one day, they will need your care and acceptance before you can clean them away and turn the lights on. For you refuse to shine the light on something that is imperfect, because you fear judgement and rejection, but you can always choose to look towards the light as the only source of true beauty and love that can help you in the cleaning process. Healing, after a long time of struggle and mess is a complex process, but a necessary one nevertheless. We are so overwhelmed by the amount of work it requires that we so often choose to run away from the light, hide in our dark corner and hope that we will never be found, hope that we will never be seen, or desperately look outwards for that love and compassion that we can no longer find within ourselves, for our soul's light no longer shines as it used to. And sometimes we just find those people that can see the light beneath all that dust and darkness that's been pilled up, those kind of light workers that understand our broken souls and manage to pick us up and see the beauty within us, when we find it so hard to see it ourselves. Sometimes I get so tired of separation, of division, of groups and different religions and belief systems. Even if you do find the truth, once you've put it into words, books and rules it already becomes distorted by the mind into something that is no longer truth. So I no longer hope for understanding, no longer hope for the opinion of a judgemental mind, but I hope to find the words that touch the soul before the mind, I hope to find the touch that warms the heart from deep inside, and hope to find that far away abandoned part of me which I've left behind.

13084 Tonight I came back to the hotel alone; the other has decided to return later on. The anxieties are already here, like the poison already prepared (jealousy, abandonment, restlessness); they merely wait for a little time to pass in order to be able to declare themselves with some propriety. I pick up a book and take a sleeping pill, "calmly." The silence of this huge hotel is echoing, indifferent, idiotic (faint murmur of draining bathtubs); the furniture and the lamps are stupid; nothing friendly that might warm ("I'm cold, let's go back to Paris). Anxiety mounts; I observe its progress, like Socrates chatting (as I am reading) and feeling the cold of the hemlock rising in his body; I hear it identify itself moving up, like an inexorable figure, against the background of the things that are here.

Tired of feeling tired? Take Liftoff, the new energy pill. Liftoff is made entirely from chemicals, with no naturally occurring ingredients. Designed to shock the nervous system into involuntary spasms, Liftoff can energize your day. Or, it can kill you. Sometimes, death comes slowly and painfully. Other times, it comes rapidly and painfully. Side effects include, but are not limited to, swelling of the throat, gagging, asphyxiation, abnormal bleeding, normal bleeding, uncontrollable laughter, uncontrollable sobbing, the desire to poke someone with a foreign object, the desire to poke oneself with a foreign object, and bed-wetting.

Being a compulsive overeater is no different from being an alcoholic or drug addict. The only difference is that you can avoid drugs and alcohol completely and you have to have a relationship with food every day for the rest of your life. It's actually the hardest addiction to live with. If you were an alcoholic and someone said to you that you were required to have a single drink three to five times a day, but were not supposed to ever drink to excess, or a drug addict who was required to take just one pill severeal times a day every day, but you're not supposed to ever take more than that...no one would ever make it through rehab.

Actually I don’t need the sleep as much as I need the escape. It’s a wonderful way to escape. I think I can’t stand it and then I just take a pill and wait for sweet nothingness to take over. At this stage in my life nothingness is a lot better than somethingness.

The baby was warm against my chest. I knew I was broken too. I wasn't like other people. I was scared and weird and anxious and sad lots of the time, and I didn't know why. My parents thought I was abnormal, I was pretty sure. They said I wasn't, but you don't get sent to a therapist if you're normal. Sometimes we really aren't supposed to be the way we are. It's not good for us. And people don't like it. You've got to change. You've got to try harder and do deep breathing and maybe one day take pills and learn tricks so you can pretend to be more like other people. Normal people. But maybe Vanessa was right, and all those other people were broken too in their own ways. Maybe we all spent too much time pretending we weren't.

There is a very dark and painful side to life, but that is natural. People in our culture think they should never be unhappy. They think that being unhappy is unnatural. They try to make it go away. They take pills or they go to therapy to "fix" themselves. They blame themselves or others for their suffering. We need to understand that sadness is as much a part of life as joy. It would be easy just to get bitter and cold while focusing on the dark side, but there is also an amazing, wonderful side of life. If you look for it, there is true magic all around us. Maybe that sounds trite to the hardened, self-protective modern ego, but there is magiv in this miraculous life. If you open yourself up, you do make yourself vulnerable to pain but the deeper the pain you experience, the deeper joy you have.

I don't think he was used to patients who were already aware of what their real problem was. He was also a bit of a pill-pusher. I balked at trying antidepressants, I just couldn't see myself taking pills to try to be less of a fraud. I said that even if they worked, how would I know if it was me or the pills? By that time I already knew I was a fraud. I knew what my problem was, I just couldn't seem to stop. I remember I spent maybe the first twenty times or so in analysis acting all open and candid but in reality sort of fencing with him or leading him around by the nose, basically showing him that I wasn't just another one of those patients who stumbled in with no clue what their real problem was or who were totally out of touch with the truth themselves.

Typically, a psychiatrist can fool a patient by telling him the root of his problem can be fixed with this pill, that support group, and more psychiatry appointments. They don't tell the patient that the really fucked up people never get better. They mask their diseases by dousing them in heavy narcotics to numb their sickness, for years, until the peaceful eternal sleep comes and takes them away.

Nothing could be purged without a body—no crying, no exertion, no pills to take away the pain or calm me down. Nothing. Instead, something ballooned inside me until I felt like I might explode. All I could do was sit there and drown in it, wondering why Claire affected me so much, wondering if she always would.

I was created, then the Society ordered the destruction of all mods. The day after I was born, the date of my death was set! So I sweated in that pill, just waiting to die. Day after day, my brothers and sisters were killed. Then I got lucky and got shipped out with a load of goods by mistake. Still, I always expected to be discovered and destroyed. I had a lot of time to think about things. I decided no one has the right to take a life. I exist! I should have the right to live and die freely!! Like humans, or even bugs. Even a mod should have that right. So I refuse to take a life. I won't kill ...not anything!

The reason the program is so successful is because alcoholics help other alcoholics. I've never met a Normie (our lingo for a person who doesn't have a problem with drugs and alcohol) who could even conceive of what it's like to be an alcoholic. Normies are always going, 'There's this new pill you can take and you won't want to shoot heroin anymore.' That shows a fundamental misunderstanding of alcoholism and drug addiction. These aren't just physical allergies, they're obsessions of the mind and maladies of the spirit. It's a threefold disease. And if it's partly a spiritual malady, then there's a spiritual cure.

If taking a pill makes you different, lie, if it changes the way-down you...that's just a screwed-up idea, you know? Who's deciding what me means - me or the employees of the factory that makes Lexapro? It's like I have this demon inside of me, and I want it gone, but the idea of removing it via pill is...I don't know...weird. But a lot of days I get over that, because I do really hate the demon.

You stop noticing pain, is the thing. You notice it when it’s really bad, or when it’s different, but… on the rare occasion someone asks me what it’s like to live with RA, I don’t ever know what to say. They ask me if its painful, and I say yes because I know intellectually it must be, because the idea of doing some of the things that other people do without thinking fills me with dread and panic, but I always think about it mechanically. I can’t do x. I don’t want to do y. I don’t continue the thought into I can’t do that because it would hurt. I don’t want to do that because then I would be in pain. You can’t live like that. There’s only so much you can carry quietly by yourself, so you turn an illness into a list of rules instead of a list of symptoms, and you take pills that don’t help, and you do stretches, and you think instead of feeling. You think.

That was the worst period of all: it is my profession to imagine, to think in images: fifty times through the day, and immediately I woke during the night, a curtain would rise and the play would begin: always the same play, Sarah making love, Sarah with X, doing the same things that we had done together, Sarah kissing in her own particular way, arching herself in the act of sex and uttering that cry like pain, Sarah in abandonment. I would take pills at night to make me sleep quickly, but I never found any pills that would keep me asleep till daylight.

If I were the Devil . . . I mean, if I were the Prince of Darkness, I would of course, want to engulf the whole earth in darkness. I would have a third of its real estate and four-fifths of its population, but I would not be happy until I had seized the ripest apple on the tree, so I should set about however necessary to take over the United States. I would begin with a campaign of whispers. With the wisdom of a serpent, I would whisper to you as I whispered to Eve: “Do as you please.” “Do as you please.” To the young, I would whisper, “The Bible is a myth.” I would convince them that man created God instead of the other way around. I would confide that what is bad is good, and what is good is “square”. In the ears of the young marrieds, I would whisper that work is debasing, that cocktail parties are good for you. I would caution them not to be extreme in religion, in patriotism, in moral conduct. And the old, I would teach to pray. I would teach them to say after me: “Our Father, which art in Washington” . . . If I were the devil, I’d educate authors in how to make lurid literature exciting so that anything else would appear dull an uninteresting. I’d threaten T.V. with dirtier movies and vice versa. And then, if I were the devil, I’d get organized. I’d infiltrate unions and urge more loafing and less work, because idle hands usually work for me. I’d peddle narcotics to whom I could. I’d sell alcohol to ladies and gentlemen of distinction. And I’d tranquilize the rest with pills. If I were the devil, I would encourage schools to refine yound intellects but neglect to discipline emotions . . . let those run wild. I would designate an athiest to front for me before the highest courts in the land and I would get preachers to say “she’s right.” With flattery and promises of power, I could get the courts to rule what I construe as against God and in favor of pornography, and thus, I would evict God from the courthouse, and then from the school house, and then from the houses of Congress and then, in His own churches I would substitute psychology for religion, and I would deify science because that way men would become smart enough to create super weapons but not wise enough to control them. If I were Satan, I’d make the symbol of Easter an egg, and the symbol of Christmas, a bottle. If I were the devil, I would take from those who have and I would give to those who wanted, until I had killed the incentive of the ambitious. And then, my police state would force everybody back to work. Then, I could separate families, putting children in uniform, women in coal mines, and objectors in slave camps. In other words, if I were Satan, I’d just keep on doing what he’s doing. (Speech was broadcast by ABC Radio commentator Paul Harvey on April 3, 1965)

The American College of Sports Medicine found that the productivity of people after exercise was an average of 65 percent higher than those who did not exercise. If I have something that's really bothering me, so much that it almost hurts my head to try to sort it out, I always find the solution in a puddle of sweat! Intense exercise is like taking a magic pill that gives you the ability to solve problems like a superhero.

We take its gifts for granted: newborns who will live more than eight decades, markets overflowing with food, clean water that appears with a flick of a finger and waste that disappears with another, pills that erase a painful infection, sons who are not sent off to war, daughters who can walk the streets in safety, critics of the powerful who are not jailed or shot, the world’s knowledge and culture available in a shirt pocket. But these are human accomplishments, not cosmic birthrights.

It only takes one mistake,' the Dan Banyan guy says, 'and nothing else you ever do will matter.' With his empty hand, he takes one of my hands. His fingers feel hot, fever-hot, and pounding with his heartbeats. He turns my hand palm-up saying, 'No matter how hard you work or how smart you become, you'll always be known for that one poor choice.' He sets the blue pill on my palm, saying, 'Do that one wrong thing- and you'll be dead for the rest of your life.

Cheryl was aided in her search by the Internet. Each time she remembered a name that seemed to be important in her life, she tried to look up that person on the World Wide Web. The names and pictures Cheryl found were at once familiar and yet not part of her conscious memory: Dr. Sidney Gottlieb, Dr. Louis 'Jolly' West, Dr. Ewen Cameron, Dr. Martin Orne and others had information by and about them on the Web. Soon, she began looking up sites related to childhood incest and found that some of the survivor sites mentioned the same names, though in the context of experiments performed on small children. Again, some names were familiar. Then Cheryl began remembering what turned out to be triggers from old programmes. 'The song, "The Green, Green Grass of home" kept running through my mind. I remembered that my father sang it as well. It all made no sense until I remembered that the last line of the song tells of being buried six feet under that green, green grass. Suddenly, it came to me that this was a suicide programme of the government. 'I went crazy. I felt that my body would explode unless I released some of the pressure I felt within, so I grabbed a [pair ofl scissors and cut myself with the blade so I bled. In my distracted state, I was certain that the bleeding would let the pressure out. I didn't know Lynn had felt the same way years earlier. I just knew I had to do it Cheryl says. She had some barbiturates and other medicine in the house. 'One particularly despondent night, I took several pills. It wasn't exactly a suicide try, though the pills could have killed me. Instead, I kept thinking that I would give myself a fifty-fifty chance of waking up the next morning. Maybe the pills would kill me. Maybe the dose would not be lethal. It was all up to God. I began taking pills each night. Each-morning I kept awakening.

There’s no reason, on paper at least, why I need these pills to get through life. I had a great childhood, loving parents, the whole package. I wasn’t beaten, abused, or expected to get nothing but As. I had nothing but love and support, but that wasn’t enough somehow. My friend Erin says we all have demons inside us, voices that whisper we’re no good, that if we don’t make this promotion or ace that exam we’ll reveal to the world exactly what kind of worthless sacks of skin and sinew we really are. Maybe that’s true. Maybe mine just have louder voices. But I don’t think it’s as simple as that. The depression I fell into after university wasn’t about exams and self-worth, it was something stranger, more chemical, something that no talking cure was going to fix. Cognitive behavioral therapy, counseling, psychotherapy—none of it really worked in the way that the pills did. Lissie says she finds the notion of chemically rebalancing your mood scary, she says it’s the idea of taking something that could alter how she really is. But I don’t see it that way; for me it’s like wearing makeup—not a disguise, but a way of making myself more how I really am, less raw. The best me I can be.

All right,” said Susan. “I’m not stupid. You’re saying humans need…fantasies to make life bearable.” REALLY? AS IF IT WAS SOME KIND OF PINK PILL? NO. HUMANS NEED FANTASY TO BE HUMAN. TO BE THE PLACE WHERE THE FALLING ANGEL MEETS THE RISING APE. “Tooth fairies? Hogfathers? Little—” YES. AS PRACTICE. YOU HAVE TO START OUT LEARNING TO BELIEVE THE LITTLE LIES. “So we can believe the big ones?” YES. JUSTICE. MERCY. DUTY. THAT SORT OF THING. “They’re not the same at all!” YOU THINK SO? THEN TAKE THE UNIVERSE AND GRIND IT DOWN TO THE FINEST POWDER AND SIEVE IT THROUGH THE FINEST SIEVE AND THEN SHOW ME ONE ATOM OF JUSTICE, ONE MOLECULE OF MERCY. AND YET—Death waved a hand. AND YET YOU ACT AS IF THERE IS SOME IDEAL ORDER IN THE WORLD, AS IF THERE IS SOME…SOME RIGHTNESS IN THE UNIVERSE BY WHICH IT MAY BE JUDGED. “Yes, but people have got to believe that, or what’s the point—” MY POINT EXACTLY. She tried to assemble her thoughts. THERE IS A PLACE WHERE TWO GALAXIES HAVE BEEN COLLIDING FOR A MILLION YEARS, said Death, apropos of nothing. DON’T TRY TO TELL ME THAT’S RIGHT. “Yes, but people don’t think about that,” said Susan. “Somewhere there was a bed…” CORRECT. STARS EXPLODE, WORLDS COLLIDE, THERE’S HARDLY ANYWHERE IN THE UNIVERSE WHERE HUMANS CAN LIVE WITHOUT BEING FROZEN OR FRIED, AND YET YOU BELIEVE THAT A…A BED IS A NORMAL THING. IT IS THE MOST AMAZING TALENT. “Talent?” OH, YES. A VERY SPECIAL KIND OF STUPIDITY. YOU THINK THE WHOLE UNIVERSE IS INSIDE YOUR HEADS. “You make us sound mad,” said Susan. A nice warm bed… NO. YOU NEED TO BELIEVE IN THINGS THAT AREN’T TRUE. HOW ELSE CAN THEY BECOME? said Death

The fatal combination of indulgence without feeling disgusts me. Strange to be both greedy and dead. For myself, I prefer to hold my desires just out of reach of appetite, to keep myself honed and sharp. I want the keen edge of longing. it is so easy to be a brute and yet it has become rather fashionable. Is that the consequence of leaving your body to science? Of assuming that another pill, another drug, another car, another pocket-sized home-movie station, a DNA transfer, or the complete freedom of choice that five hundred TV channels must bring, will make everything all right? Will soothe the nagging pain in the heart that the latest laser scan refuses to diagnose? The doctor's surgery is full of men and women who do not know why they are unhappy. "Take this", says the Doctor, "you'll soon feel better." They do not feel better, because, little by little, they cease to feel at all.

Why do you think she did it?” I asked as we stepped back into the sunlight. For that’s all any of us were thinking, had been thinking, since we got the news. Mustn’t Tiffany have hoped that whatever pills she’d taken wouldn’t be strong enough and that her failed attempt would lead her back into our fold? How could anyone purposefully leave us—us, of all people? This is how I thought of it, for though I’ve often lost faith in myself, I’ve never lost faith in my family, in my certainty that we are fundamentally better than everyone else. It’s an archaic belief, one I haven’t seriously reconsidered since my late teens, but still I hold it. Ours is the only club I’d ever wanted to be a member of, so I couldn’t imagine quitting. Backing off for a year or two was understandable, but to want out so badly that you’d take your own life?

I tend to think of human beings as huge, rubbery test tubes, too, with chemical reactions seething inside. When I was a boy, I saw a lot of people with goiters. So did Dwayne Hoover, the Pontiac dealer who is the hero of this book. Those unhappy Earthlings had such swollen thyroid glands that they seemed to have zucchini squash growing from their throats. All they had to do in order to have ordinary lives, it turned out, was to consume less than one-millionth of an ounce of iodine every day. My own mother wrecked her brains with chemicals, which were supposed to make her sleep. When I get depressed, I take a little pill, and I cheer up again. And so on. So it is a big temptation to me, when I create a character for a novel, to say that he is what he is because of faulty wiring, or because of microscopic amounts of chemicals which he ate or failed to eat on that particular day.

In these days of physical fitness, hair dye, and plastic surgery, you can live much of your life without feeling or even looking old. But then one day, your knee goes, or your shoulder, or your back, or your hip. Your hot flashes come to an end; things droop. Spots appear. Your cleavage looks like a peach pit. If your elbows faced forward, you would kill yourself. You’re two inches shorter than you used to be. You’re ten pounds fatter and you cannot lose a pound of it to save your soul. Your hands don’t work as well as they once did and you can’t open bottles, jars, wrappers, and especially those gadgets that are encased tightly in what seems to be molded Mylar. If you were stranded on a desert island and your food were sealed in plastic packaging, you would starve to death. You take so many pills in the morning you don’t have room for breakfast. You lose close friends and discover one of the worst truths of old age: they’re irreplaceable. People who run four miles a day and eat only nuts and berries drop dead. People who drink a quart of whiskey and smoke two packs of cigarettes a day drop dead. You are suddenly in a lottery, the ultimate game of chance, and someday your luck will run out. Everybody dies. There’s nothing you can do about it. Whether or not you eat six almonds a day. Whether or not you believe in God.

Dave hands me the bread. Josh takes some chicken onto his plate. The silence is homicidal. Emily finishes her wine and Dave pours her more. For such a small thing, Emily can really pack it away. “Winnie has worms,” I tell the table, and spread some butter on my bread. “Took her to the vet earlier. I was so worried I was going to have to treat it with some ointment in her butt, but—nope—just a pill.” I take a sip of wine and grin at them. Josh puts his fork down and cups his forehead. But in a few beats they all break into laughter, and Emily looks over at me with my favorite kind of fondness. “She doesn’t really have worms. I was just kidding.” I am nothing if not a decent icebreaker.

More troubling than this oddly timed debate about birth control is the vehemence with which women need to justify or explain why they take birth control—health reasons, to regulate periods, you know, as if there’s anything wrong with taking birth control simply because you want to have sex without that sex resulting in pregnancy. In certain circles, birth control is being framed as whore medicine. We are now dealing with a bizarre new morality where a woman cannot simply say, in one way or another, “I’m on the pill because I like dick.” It’s extremely regressive for women to feel like they need to make it seem like they are using birth control for reasons other than what birth control was originally designed for: to control birth.

Since my symptoms began 13 years ago, I’ve tried every form of pain management I could access — NSAIDS, nonopioid analgesics, neurologic medications, acupuncture, laser therapy, physical therapy, prolotherapy, massage, and trigger-point injections. Most of these have been unhelpful; others provide temporary relief, often at great expense. At the end of the day, when my body is fully depleted of its resources and in the most pain, a single dose of Percocet is the only tool that silences the pain enough for me to fall asleep. I honestly don’t know what I’d do if Percocet became unavailable to me, and the very thought scares me. I’ve been taking it for five years. To avoid any chance of addiction, I only take it at night and have stayed on a consistently low dose.

Here's how you make absolutely sure that you'll keep getting crazier by the day: - Ignore everything your psychiatrist tells you. Disregard all his warnings about the way you're living your life - in fact, do absolutely everything he tells you not to. - Don't always take your pills. They're a hassle, and what if they make you dull? You don't need them. And if you're going to take the pills, take them with a glass of wine. It will make the mood swings even more exciting. - Don't sleep; you've got to make sure your body clock is as fucked up as possible. The less you sleep, the more manic you'll get, until soon you'll go completely over the edge. - Drink caffeine. Tons of it. Take your morning pills with coffee. It can't hurt. - Work around the clock - it's important to put yourself under as much stress as possible. - Eating normally would stabilize your blood sugar, so don't do that; it's better to keep your body in as unstable a state as you possibly can for maximum results. - And, above all else, drink like a fish.

You will encounter resentful, sneering non-readers who will look at you from their beery, leery eyes, as they might some form of sub-hominid anomaly, bookimus maximus. You will encounter redditters, youtubers, blogspotters, wordpressers, twitterers, and facebookers with wired-open eyes who will shout at from you from their crazy hectoring mouths about the liberal poison of literature. You will encounter the gamers with their twitching fingers who will look upon you as a character to lock crosshairs on and blow to smithereens. You will encounter the stoners and pill-poppers who will ignore you, and ask you if you have read Jack Keroauc’s On the Road, and if you haven’t, will lecture you for two hours on that novel and refuse to acknowledge any other books written by anyone ever. You will encounter the provincial retirees, who have spent a year reading War & Peace, who strike the attitude that completing that novel is a greater achievement than the thousands of books you have read, even though they lost themselves constantly throughout the book and hated the whole experience. You will encounter the self-obsessed students whose radical interpretations of Agnes Grey and The Idiot are the most important utterance anyone anywhere has ever made with their mouths, while ignoring the thousands of novels you have read. You will encounter the parents and siblings who take every literary reference you make back to the several books they enjoyed reading as a child, and then redirect the conversation to what TV shows they have been watching. You will encounter the teachers and lecturers, for whom any text not on their syllabus is a waste of time, and look upon you as a wayward student in need of their salvation. You will encounter the travellers and backpackers who will take pity on you for wasting your life, then tell you about the Paulo Coelho they read while hostelling across Europe en route to their spiritual pilgrimage to New Delhi. You will encounter the hard-working moaners who will tell you they are too busy working for a living to sit and read all day, and when they come home from a hard day’s toil, they don’t want to sit and read pretentious rubbish. You will encounter the voracious readers who loathe competition, and who will challenge you to a literary duel, rather than engage you in friendly conversation about your latest reading. You will encounter the slack intellectuals who will immediately ask you if you have read Finnegans Wake, and when you say you have, will ask if you if you understood every line, and when you say of course not, will make some point that generally alludes to you being a halfwit. Fuck those fuckers.

We got to the moment when I wake up from being "mostly dead" and say: "I'll beat you both apart! I'll take you both together!", Fezzik cups my mouth with his hand, and answers his own question to Inigo as to how long it might be before Miracle Max's pill begins to take effect by stating: "I guess not very long." As soon as he delivered that line, there issued forth from Andre' one of the most monumental farts any of us had ever heard. Now I suppose you wouldn't expect a man of Andre's proportions to pass gas quietly or unobtrusively, but this particular one was truly epic, a veritable symphony of gastric distress that roared for more than several seconds and shook the very foundations of the wood and plaster set were now grabbing on to out of sheer fear. It was long enough and loud enough that every member of the crew had time to stop what they were doing and take notice. All I can say is that it was a wind that could have held up in comparison to the one Slim Pickens emitted int eh campfire scene in Mel Brooks's Blazing Saddles, widely acknowledged as the champion of all cinematic farts. Except of course, this one wasn't in the script.

I looked a coyote right in the face On the road to Baljennie near my old home town He went running thru the whisker wheat Chasing some prize down And a hawk was playing with him Coyote was jumping straight up and making passes He had those same eyes just like yours Under your dark glasses Privately probing the public rooms And peeking thru keyholes in numbered doors Where the players lick their wounds And take their temporary lovers And their pills and powders to get them thru this passion play No regrets Coyote I just get off up aways You just picked up a hitcher A prisoner of the white lines on the freeway Coyote's in the coffee shop He's staring a hole in his scrambled eggs He picks up my scent on his fingers While he's watching the waitresses' legs He's too far from the Bay of Fundy From appaloosas and eagles and tides And the air conditioned cubicles And the carbon ribbon rides Are spelling it out so clear Either he's going to have to stand and fight Or take off out of here I tried to run away myself To run away and wrestle with my ego And with this flame You put here in this Eskimo In this hitcher In this prisoner Of the fine white lines Of the white lines on the free freeway

When The Matrix debuted in 1999, it was a huge box-office success. It was also well received by critics, most of whom focused on one of two qualities—the technological (it mainstreamed the digital technique of three-dimensional “bullet time,” where the on-screen action would freeze while the camera continued to revolve around the participants) or the philosophical (it served as a trippy entry point for the notion that we already live in a simulated world, directly quoting philosopher Jean Baudrillard’s 1981 reality-rejecting book Simulacra and Simulation). If you talk about The Matrix right now, these are still the two things you likely discuss. But what will still be interesting about this film once the technology becomes ancient and the philosophy becomes standard? I suspect it might be this: The Matrix was written and directed by “the Wachowski siblings.” In 1999, this designation meant two brothers; as I write today, it means two sisters. In the years following the release of The Matrix, the older Wachowski (Larry, now Lana) completed her transition from male to female. The younger Wachowski (Andy, now Lilly) publicly announced her transition in the spring of 2016. These events occurred during a period when the social view of transgender issues radically evolved, more rapidly than any other component of modern society. In 1999, it was almost impossible to find any example of a trans person within any realm of popular culture; by 2014, a TV series devoted exclusively to the notion won the Golden Globe for Best Television Series. In the fifteen-year window from 1999 to 2014, no aspect of interpersonal civilization changed more, to the point where Caitlyn (formerly Bruce) Jenner attracted more Twitter followers than the president (and the importance of this shift will amplify as the decades pass—soon, the notion of a transgender US president will not seem remotely implausible). So think how this might alter the memory of The Matrix: In some protracted reality, film historians will reinvestigate an extremely commercial action movie made by people who (unbeknownst to the audience) would eventually transition from male to female. Suddenly, the symbolic meaning of a universe with two worlds—one false and constructed, the other genuine and hidden—takes on an entirely new meaning. The idea of a character choosing between swallowing a blue pill that allows him to remain a false placeholder and a red pill that forces him to confront who he truly is becomes a much different metaphor. Considered from this speculative vantage point, The Matrix may seem like a breakthrough of a far different kind. It would feel more reflective than entertaining, which is precisely why certain things get remembered while certain others get lost.

Although the idea has been around for ages, most depressed people do not really comprehend it. If you feel depressed, you may think it is because of bad things that have happened to you. You may think you are inferior and destined to be unhappy because you failed in your work or were rejected by someone you loved. You may think your feelings of inadequacy result from some personal defect—you may feel convinced you are not smart enough, successful enough, attractive enough, or talented enough to feel happy and fulfilled. You may think your negative feelings are the result of an unloving or traumatic childhood, or bad genes you inherited, or a chemical or hormonal imbalance of some type. Or you may blame others when you get upset: “It’s these lousy stupid drivers that tick me off when I drive to work! If it weren’t for these jerks, I’d be having a perfect day!” And nearly all depressed people are convinced that they are facing some special, awful truth about themselves and the world and that their terrible feelings are absolutely realistic and inevitable. Certainly all these ideas contain an important gem of truth—bad things do happen, and life beats up on most of us at times. Many people do experience catastrophic losses and confront devastating personal problems. Our genes, hormones, and childhood experiences probably do have an impact on how we think and feel. And other people can be annoying, cruel, or thoughtless. But all these theories about the causes of our bad moods have the tendency to make us victims—because we think the causes result from something beyond our control. After all, there is little we can do to change the way people drive at rush hour, or the way we were treated when we were young, or our genes or body chemistry (save taking a pill). In contrast, you can learn to change the way you think about things, and you can also change your basic values and beliefs. And when you do, you will often experience profound and lasting changes in your mood, outlook, and productivity. That, in a nutshell, is what cognitive therapy is all about. The theory is straightforward

Two large trials of antioxidants were set up after Peto’s paper (which rather gives the lie to nutritionists’ claims that vitamins are never studied because they cannot be patented: in fact there have been a great many such trials, although the food supplement industry, estimated by one report to be worth over $50 billion globally, rarely deigns to fund them). One was in Finland, where 30,000 participants at high risk of lung cancer were recruited, and randomised to receive either ß-carotene, vitamin E, or both, or neither. Not only were there more lung cancers among the people receiving the supposedly protective ß-carotene supplements, compared with placebo, but this vitamin group also had more deaths overall, from both lung cancer and heart disease. The results of the other trial were almost worse. It was called the ‘Carotene and Retinol Efficacy Trial’, or ‘CARET’, in honour of the high p-carotene content of carrots. It’s interesting to note, while we’re here, that carrots were the source of one of the great disinformation coups of World War II, when the Germans couldn’t understand how our pilots could see their planes coming from huge distances, even in the dark. To stop them trying to work out if we’d invented anything clever like radar (which we had), the British instead started an elaborate and entirely made-up nutritionist rumour. Carotenes in carrots, they explained, are transported to the eye and converted to retinal, which is the molecule that detects light in the eye (this is basically true, and is a plausible mechanism, like those we’ve already dealt with): so, went the story, doubtless with much chortling behind their excellent RAF moustaches, we have been feeding our chaps huge plates of carrots, to jolly good effect. Anyway. Two groups of people at high risk of lung cancer were studied: smokers, and people who had been exposed to asbestos at work. Half were given 3-carotene and vitamin A, while the other half got placebo. Eighteen thousand participants were due to be recruited throughout its course, and the intention was that they would be followed up for an average of six years; but in fact the trial was terminated early, because it was considered unethical to continue it. Why? The people having the antioxidant tablets were 46 per cent more likely to die from lung cancer, and 17 per cent more likely to die of any cause,* than the people taking placebo pills. This is not news, hot off the presses: it happened well over a decade ago.

Depression goes through stages, but if left unchecked and not treated, this elevator ride will eventually go all the way to the bottom floor. And finally you find yourself bereft of choices, unable to figure out a way up or out, and pretty soon one overarching impulse begins winning the battle for your mind: “Kill yourself.” And once you get over the shock of those words in your head, the horror of it, it begins to start sounding appealing, even possessing a strange resolve, logic. In fact, it’s the only thing you have left that is logical. It becomes the only road to relief. As if just the planning of it provides the first solace you’ve felt that you can remember. And you become comfortable with it. You begin to plan it and contemplate the details of how best to do it, as if you were planning travel arrangements for a vacation. You just have to get out. O-U-T. You see the white space behind the letter O? You just want to crawl through that O and be out of this inescapable hurt that is this thing they call clinical depression. “How am I going to do this?” becomes the only tape playing. And if you are really, really, really depressed and you’re really there, you’re gonna find a way. I found a way. I had a way. And I did it. I made sure Opal was out of the house and on a business trip. My planning took a few weeks. I knew exactly how I was going to do it: I didn’t want to make too much of a mess. There was gonna be no blood, no drama. There was just going to be, “Now you see me, now you don’t.” That’s what it was going to be. So I did it. And it was over. Or so I thought. About twenty-four hours later I woke up. I was groggy; zoned out to the point at which I couldn’t put a sentence together for the next couple of days. But I was semifunctional, and as these drugs and shit that I took began to wear off slowly but surely, I realized, “Okay, I fucked up. I didn’t make it.” I thought I did all the right stuff, left no room for error, but something happened. And this perfect, flawless plan was thwarted. As if some force rebuked me and said, “Not yet. You’re not going anywhere.” The only reason I could have made it, after the amount of pills and alcohol and shit I took, was that somebody or something decided it wasn’t my time. It certainly wasn’t me making that call. It was something external. And when you’re infused with the presence of this positive external force, which is so much greater than all of your efforts to the contrary, that’s about as empowering a moment as you can have in your life. These days we have a plethora of drugs one can take to ameliorate the intensity of this lack of hope, lack of direction, lack of choice. So fuck it and don’t be embarrassed or feel like you can handle it yourself, because lemme tell ya something: you can’t. Get fuckin’ help. The negative demon is strong, and you may not be as fortunate as I was. My brother wasn’t. For me, despair eventually gave way to resolve, and resolve gave way to hope, and hope gave way to “Holy shit. I feel better than I’ve ever felt right now.” Having actually gone right up to the white light, looked right at it, and some force in the universe turned me around, I found, with apologies to Mr. Dylan, my direction home. I felt more alive than I’ve ever felt. I’m not exaggerating when I say for the next six months I felt like Superman. Like I’m gonna fucking go through walls. That’s how strong I felt. I had this positive force in me. I was saved. I was protected. I was like the only guy who survived and walked away from a major plane crash. I was here to do something big. What started as the darkest moment in my life became this surge of focus, direction, energy, and empowerment.

Antidepression medication is temperamental. Somewhere around fifty-nine or sixty I noticed the drug I’d been taking seemed to have stopped working. This is not unusual. The drugs interact with your body chemistry in different ways over time and often need to be tweaked. After the death of Dr. Myers, my therapist of twenty-five years, I’d been seeing a new doctor whom I’d been having great success with. Together we decided to stop the medication I’d been on for five years and see what would happen... DEATH TO MY HOMETOWN!! I nose-dived like the diving horse at the old Atlantic City steel pier into a sloshing tub of grief and tears the likes of which I’d never experienced before. Even when this happens to me, not wanting to look too needy, I can be pretty good at hiding the severity of my feelings from most of the folks around me, even my doctor. I was succeeding well with this for a while except for one strange thing: TEARS! Buckets of ’em, oceans of ’em, cold, black tears pouring down my face like tidewater rushing over Niagara during any and all hours of the day. What was this about? It was like somebody opened the floodgates and ran off with the key. There was NO stopping it. 'Bambi' tears... 'Old Yeller' tears... 'Fried Green Tomatoes' tears... rain... tears... sun... tears... I can’t find my keys... tears. Every mundane daily event, any bump in the sentimental road, became a cause to let it all hang out. It would’ve been funny except it wasn’t. Every meaningless thing became the subject of a world-shattering existential crisis filling me with an awful profound foreboding and sadness. All was lost. All... everything... the future was grim... and the only thing that would lift the burden was one-hundred-plus on two wheels or other distressing things. I would be reckless with myself. Extreme physical exertion was the order of the day and one of the few things that helped. I hit the weights harder than ever and paddleboarded the equivalent of the Atlantic, all for a few moments of respite. I would do anything to get Churchill’s black dog’s teeth out of my ass. Through much of this I wasn’t touring. I’d taken off the last year and a half of my youngest son’s high school years to stay close to family and home. It worked and we became closer than ever. But that meant my trustiest form of self-medication, touring, was not at hand. I remember one September day paddleboarding from Sea Bright to Long Branch and back in choppy Atlantic seas. I called Jon and said, “Mr. Landau, book me anywhere, please.” I then of course broke down in tears. Whaaaaaaaaaa. I’m surprised they didn’t hear me in lower Manhattan. A kindly elderly woman walking her dog along the beach on this beautiful fall day saw my distress and came up to see if there was anything she could do. Whaaaaaaaaaa. How kind. I offered her tickets to the show. I’d seen this symptom before in my father after he had a stroke. He’d often mist up. The old man was usually as cool as Robert Mitchum his whole life, so his crying was something I loved and welcomed. He’d cry when I’d arrive. He’d cry when I left. He’d cry when I mentioned our old dog. I thought, “Now it’s me.” I told my doc I could not live like this. I earned my living doing shows, giving interviews and being closely observed. And as soon as someone said “Clarence,” it was going to be all over. So, wisely, off to the psychopharmacologist he sent me. Patti and I walked in and met a vibrant, white-haired, welcoming but professional gentleman in his sixties or so. I sat down and of course, I broke into tears. I motioned to him with my hand; this is it. This is why I’m here. I can’t stop crying! He looked at me and said, “We can fix this.” Three days and a pill later the waterworks stopped, on a dime. Unbelievable. I returned to myself. I no longer needed to paddle, pump, play or challenge fate. I didn’t need to tour. I felt normal.

In 1994, Friedman wrote a memo marked “Very Confidential” to Raymond, Mortimer, and Richard Sackler. The market for cancer pain was significant, Friedman pointed out: four million prescriptions a year. In fact, there were three-quarters of a million prescriptions just for MS Contin. “We believe that the FDA will restrict our initial launch of OxyContin to the Cancer pain market,” Friedman wrote. But what if, over time, the drug extended beyond that? There was a much greater market for other types of pain: back pain, neck pain, arthritis, fibromyalgia. According to the wrestler turned pain doctor John Bonica, one in three Americans was suffering from untreated chronic pain. If that was even somewhat true, it represented an enormous untapped market. What if you could figure out a way to market this new drug, OxyContin, to all those patients? The plan would have to remain secret for the time being, but in his memo to the Sacklers, Friedman confirmed that the intention was “to expand the use of OxyContin beyond Cancer patients to chronic non-malignant pain.” This was a hugely audacious scheme. In the 1940s, Arthur Sackler had watched the introduction of Thorazine. It was a “major” tranquilizer that worked wonders on patients who were psychotic. But the way the Sackler family made its first great fortune was with Arthur’s involvement in marketing the “minor” tranquilizers Librium and Valium. Thorazine was perceived as a heavy-duty solution for a heavy-duty problem, but the market for the drug was naturally limited to people suffering from severe enough conditions to warrant a major tranquilizer. The beauty of the minor tranquilizers was that they were for everyone. The reason those drugs were such a success was that they were pills that you could pop to relieve an extraordinary range of common psychological and emotional ailments. Now Arthur’s brothers and his nephew Richard would make the same pivot with a painkiller: they had enjoyed great success with MS Contin, but it was perceived as a heavy-duty drug for cancer. And cancer was a limited market. If you could figure out a way to market OxyContin not just for cancer but for any sort of pain, the profits would be astronomical. It was “imperative,” Friedman told the Sacklers, “that we establish a literature” to support this kind of positioning. They would suggest OxyContin for “the broadest range of use.” Still, they faced one significant hurdle. Oxycodone is roughly twice as potent as morphine, and as a consequence OxyContin would be a much stronger drug than MS Contin. American doctors still tended to take great care in administering strong opioids because of long-established concerns about the addictiveness of these drugs. For years, proponents of MS Contin had argued that in an end-of-life situation, when someone is in a mortal fight with cancer, it was a bit silly to worry about the patient’s getting hooked on morphine. But if Purdue wanted to market a powerful opioid like OxyContin for less acute, more persistent types of pain, one challenge would be the perception, among physicians, that opioids could be very addictive. If OxyContin was going to achieve its full commercial potential, the Sacklers and Purdue would have to undo that perception.