Pfc Quotes

Huxley: "Tell me something Bryce, do you know the difference between a Jersey, a Guernsey, a Holstein, and an Ayershire?" Bryce: "No." Huxley: "Seabags Brown does." Bryce: "I don't see what that has to do..." Huxley: "What do you know about Gaelic history?" Bryce: "Not much." Huxley: "Then why don't you sit down one day with Gunner McQuade. He is an expert. Speaks the language, too." Bryce: "I don't..." Huxley: " What do you know about astronomy?" Bryce: "A little." Huxley: "Discuss it with Wellman, he held a fellowship." Bryce: "This is most puzzling." Huxley: "What about Homer, ever read Homer?" Bryce: "Of course I've read Homer." Huxley: "In the original Greek?" Bryce: "No" Huxley: "Then chat with Pfc. Hodgkiss. Loves to read the ancient Greek." Bryce: "Would you kindly get to the point?" Huxley: "The point is this, Bryce. What makes you think you are so goddam superior? Who gave you the bright idea that you had a corner on the world's knowledge? There are privates in this battalion who can piss more brains down a slit trench then you'll ever have. You're the most pretentious, egotistical individual I've ever encountered. Your superiority complex reeks. I've seen the way you treat men, like a big strutting peacock. Why, you've had them do everything but wipe your ass.

take an average heterosexual male and expose him to a particular stimulus, and his PFC becomes more likely to decide that jaywalking is a good idea. What’s the stimulus? The proximity of an attractive woman. I know, pathetic.

Well, the PFC is trying to cheat nature. It’s time to stand up for ourselves. We … will … live!

To summarize this section, when you try to do the harder thing that’s better, the PFC you’re working with is going to be displaying the consequences of whatever the previous years have handed you.

Damasio has produced an influential theory about emotion-laden decision making, rooted in the philosophies of Hume and William James; this will soon be discussed.61 Briefly, the frontal cortex runs “as if” experiments of gut feelings—“How would I feel if this outcome occurred?”—and makes choices with the answer in mind. Damaging the vmPFC, thus removing limbic input to the PFC, eliminates gut feelings, making decisions harder.

They lied, you know,” said Cpl. Allan Richmond. He hugged the wall next to Owens. Beside him, PFC Bucky Hatton crouched low, a Browning 1911 semiautomatic gripped tightly in his hand. “Who?” asked Bart, glad to be out of the wind and rain, even if it was only for a short time. “The assholes who said France was beautiful.

Chapter 3 discusses some unsettling research—stick your average person in a brain scanner, and show him a picture of someone of another race for only a tenth of a second. This is too fast for him to be aware of what he saw. But thanks to that anatomical shortcut, the amygdala knows . . . and activates. In contrast, show the picture for a longer time. Again the amygdala activates, but then the cognitive dlPFC does as well, inhibiting the amygdala—the effort to control what is for most people an unpalatable initial response.

someone’s hand being poked with a needle, and subjects have an “isomorphic sensorimotor” response—hands tense in empathy. Among both whites and blacks, the response is blunted for other-race hands; the more the implicit racism, the more blunting. Similarly, among subjects of both races, there’s more activation of the (emotional) medial PFC when considering misfortune befalling a member of their own race than of another race.

Dopamine is not just about reward anticipation; it fuels the goal-directed behavior needed to gain that reward; dopamine “binds” the value of a reward to the resulting work. It’s about the motivation arising from those dopaminergic projections to the PFC that is needed to do the harder thing (i.e., to work). In other words, dopamine is not about the happiness of reward. It’s about the happiness of pursuit of reward that has a decent chance of occurring.fn50,99

No surprise, the socioeconomic status of a child’s family predicts the size, volume, and gray matter content of the PFC in kindergarteners. Same thing in toddlers. In six-month-olds. In four-week-olds. You want to scream at how unfair life can be.

Mischel’s next step made his studies iconic — he tracked the kids forward, seeing if marshmallow wait time predicted anything about their adulthoods . [...] Five-year-old champs at marshmallow patience averaged higher SAT scores in high school (compared with those who couldn’t wait). [...] Forty years post-marshmallow, they excelled at frontal function, had more PFC [Prefrontal cortex] activation during a frontal task, and had lower BMIs. A gazillion-dollar brain scanner doesn’t hold more predictive power than one marshmallow.

Something scary is happening; you don’t want reason getting in the way of survival. The second is that the locus coeruleus is flooding the brain with noradrenaline, compromising the ability to override instincts and impulses. The PFC is the part of the kid’s brain that puts the brakes on impulses and helps him or her make smarter decisions. Telling a kid to sit still, concentrate, and ignore stimuli that are flooding his brain with the need to act is a lot to ask. This down-regulation of the PFC can have different consequences for different people. For some, it results in an inability to concentrate and solve problems, but in others it manifests as impulsive behavior and aggression.

Interestingly, pathological liars have atypically large amounts of white matter in the prefrontal cortex, indicating more complex wiring.

Maybe we should consider this for a second. Maybe, instead of surrendering the fight because a Marine made a mistake, maybe we should train Santiago. What do you think, I'm just spit-balling, but maybe we, as officers, have a responsibility to this country to see that the men charged with its security are trained professionals. Maybe we have that responsibility to other members of the Corps. Yes, yes, I'm certain I once read something like that. See, and now I'm trying to think about how I'd feel if some Marine got hurt or killed because a Pfc. in my command didn't know what the fuck he was doing. And I'm trying to think about how the other members of his unit might feel, putting their lives in the hands of a man they can't count on...and this brief meditation has brought me around to thinking that your suggestion of transferring Private Santiago off base, while expeditious, and certainly painless, might not be, in a manner of speaking, the "American Way".

The autobiographical self (D’Amasio 2000) incorporates the reflective self and some of the emotional self, and it provides the sense of “I” having a unique past and future. The core self involves an underlying and largely nonverbal feeling of “I” that has little sense of the past or the future. If the PFC—which provides most of the neural substrate of the autobiographical self—were to be damaged, the core self would remain, though with little sense of continuity with the past or future. On the other hand, if the subcortical and brain stem structures which the core self relies upon were damaged, then both the core and autobiographical selves would disappear, which suggests that the core self is the neural and mental foundation of the autobiographical self (D’Amasio 2000). When your mind is very quiet, the autobiographical self seems largely absent, which presumably corresponds to a relative deactivation of its neural substrate. Meditations that still the mind, such as the concentration practices we explored in the previous chapter, improve conscious control over that deactivation process.

It is the punisher’s mind-set where everything must be changed. The difficulty of this is explored in the superb book The Punisher’s Brain: The Evolution of Judge and Jury (2014) by Morris Hoffman, a practicing judge and legal scholar.31 He reviews the reasons for punishment: As we see from game theory studies, because punishment fosters cooperation. Because it is in the fabric of the evolution of sociality. And most important, because it can feel good to punish, to be part of a righteous and self-righteous crowd at a public hanging, knowing that justice is being served. This is a deep, atavistic pleasure. Put people in brain scanners, give them scenarios of norm violations. Decision making about culpability for the violation correlates with activity in the cognitive dlPFC. But decision making about appropriate punishment activates the emotional vmPFC, along with the amygdala and insula; the more activation, the more punishment.32 The decision to punish, the passionate motivation to do so, is a frothy limbic state. As are the consequences of punishing—when subjects punish someone for making a lousy offer in an economic game, there’s activation of dopaminergic reward systems. Punishment that feels just feels good.

Imagine yourself having a fight with your romantic partner. The tension of the situation makes your limbic system run at full throttle and you become flooded with stress hormones like cortisol and adrenalin. The high levels of these chemicals suddenly make you so damn angry, that you burst out in front of your partner saying, “I wish you die, so that I can have some peace in my life”. Given the stress of the situation through highly active limbic system, your PFC loses its freedom to take the right decision and you burst out with foul language in front of your partner, that may ruin your relationship. In simple terms due to your mental instability, you lost your free will to make the right decision. But when the conversation is over, and you relax for a while, your stress hormone levels come down to normal, and you regain your usual cheerful state of mind. Immediately, your PFC starts analyzing the explosive conversation you had with your partner. Healthy activity of the entire frontal lobes, especially the PFC suddenly overwhelms you with a feeling of guilt. Your brain makes you realize, that you have done something devilish. As a result, now you find yourself making the willful decision of apologizing to your partner and making up to him or her, no matter how much effort it takes, because your PFC comes up the solution that it is the healthiest thing to do for your personal life. From this you can see, that what you call free will is something that is not consistent. It changes based on your mental health. Mental instability or illness, truly cripples your free will. And the healthier your frontal lobes are, the better you can take good decisions. And the most effective way to keep your frontal lobes healthy is to practice some kind of meditation.

Neuroimaging studies show the PFC reining in more emotional brain regions in the name of doing (or thinking) the right thing. Stick a volunteer in a brain scanner and flash up pictures of faces. And in a depressing, well-replicated finding, flash up the face of someone of another race and in about 75 percent of subjects, there is activation of the amygdala, the brain region central to fear, anxiety, and aggression.[*] In under a tenth of a second.[*] And then the PFC does the harder thing. In most of those subjects, a few seconds after the amygdala activates, the PFC kicks in, turning off the amygdala. It’s a delayed frontocortical voice—“Don’t think that way. That’s not who I am.” And who are the folks in which the PFC doesn’t muzzle the amygdala? People whose racism is avowedly, unapologetically explicit—“That is who I am.”[13] In another experimental paradigm, a subject in a brain scanner plays an online game with two other people—each is represented by a symbol on the screen, forming a triangle. They toss a virtual ball around—the subject presses one of two buttons, determining which of the two symbols the ball is tossed to; the other two toss it to each other, toss it back to the subject. This goes on for a while, everyone having a fine time, and then, oh no, the other two people stop tossing the ball to the subject. It’s the middle-school nightmare: “They know I’m a dork.” The amygdala rapidly activates, along with the insular cortex, a region associated with disgust and distress. And then, after a delay, the PFC inhibits these other regions—“Get this in perspective; this is just a stupid game.” In a subset of individuals, however, the PFC doesn’t activate as much, and the amygdala and insular cortex just keep going, as the subject feels more subjective distress. Who are these impaired individuals? Teenagers—the PFC isn’t up to the task yet of dismissing social ostracism as meaningless. There you have it.[*]

For millennia, sages have proclaimed how outer beauty reflects inner goodness. While we may no longer openly claim that, beauty-is-good still holds sway unconsciously; attractive people are judged to be more honest, intelligent, and competent; are more likely to be elected or hired, and with higher salaries; are less likely to be convicted of crimes, then getting shorter sentences. Jeez, can’t the brain distinguish beauty from goodness? Not especially. In three different studies, subjects in brain scanners alternated between rating the beauty of something (e.g., faces) or the goodness of some behavior. Both types of assessments activated the same region (the orbitofrontal cortex, or OFC); the more beautiful or good, the more OFC activation (and the less insula activation). It’s as if irrelevant emotions about beauty gum up cerebral contemplation of the scales of justice. Which was shown in another study—moral judgments were no longer colored by aesthetics after temporary inhibition of a part of the PFC that funnels information about emotions into the frontal cortex.[*] “Interesting,” the subject is told. “Last week, you sent that other person to prison for life. But just now, when looking at this other person who had done the same thing, you voted for them for Congress—how come?” And the answer isn’t “Murder is definitely bad, but OMG, those eyes are like deep, limpid pools.” Where did the intent behind the decision come from? The fact that the brain hasn’t had enough time yet to evolve separate circuits for evaluating morality and aesthetics.[6] Next, want to make someone more likely to choose to clean their hands? Have them describe something crummy and unethical they’ve done. Afterward, they’re more likely to wash their hands or reach for hand sanitizer than if they’d been recounting something ethically neutral they’d done. Subjects instructed to lie about something rate cleansing (but not noncleansing) products as more desirable than do those instructed to be honest. Another study showed remarkable somatic specificity, where lying orally (via voice mail) increased the desire for mouthwash, while lying by hand (via email) made hand sanitizers more desirable. One neuroimaging study showed that when lying by voice mail boosts preference for mouthwash, a different part of the sensory cortex activates than when lying by email boosts the appeal of hand sanitizers. Neurons believing, literally, that your mouth or hand, respectively, is dirty.