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The study of cannabinoids goes back over a century. CBN, at first thought to be the principal psycho-active agent, was identified in the 1890s, then, in the 1930s, CBD was isolated. However, it was not until 1964, with the post-war advances in organic chemistry, that two Israeli chemists, Gaoni and Mechoulam, isolated and identified THC. Since then, studies have discovered a long list of other cannabinoids, many of which have yet to be fully investigated.
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