Anemia Disease Quotes

Needless to say, jamming deformed, drugged, overstressed birds together in a filthy, waste-coated room is not very healthy. Beyond deformities, eye damage, blindness, bacterial infections of bones, slipped vertebrae, paralysis, internal bleeding, anemia, slipped tendons, twisted lower legs and necks, respiratory diseases, and weakened immune systems are frequent and long-standing problems on factory farms.

This is how I recognize an authentic poet: by frequenting him, living a long time in the intimacy of his work, something changes in myself, not so much my inclinations or my tastes as my very blood, as if a subtle disease had been injected to alter its course, its density and nature. To live around a true poet is to feel your blood run thin, to dream a paradise of anemia, and to hear, in your veins, the rustle of tears.

Skeletal remains show that plant-fed humans were a head shorter than meat-eating hunters, prone to anemia, infectious diseases, rotten teeth, and bone disorders.

Old measures of health not only have failed to improve significantly but have stayed the same: some have even worsened. Mainstream newspapers and magazines often report disease in an ethnocentric manner that shrouds its true cost among African Americans. For example, despite the heavy emphasis on genetic ailments among blacks, fewer than 0.5 percent of black deaths—that’s less than one death in two hundred—can be attributed to hereditary disorders such as sickle-cell anemia. A closer look at the troubling numbers reveals that blacks are dying not of exotic, incurable, poorly understood illnesses nor of genetic diseases that target only them, but rather from common ailments that are more often prevented and treated among whites than among blacks.

The scariest thing is that nobody seems to be considering the impact on those wild fish of fish farming on the scale that is now being proposed on the coast of Norway or in the open ocean off the United States. Fish farming, even with conventional techniques, changes fish within a few generations from an animal like a wild buffalo or a wildebeest to the equivalent of a domestic cow. Domesticated salmon, after several generations, are fat, listless things that are good at putting on weight, not swimming up fast-moving rivers. When they get into a river and breed with wild fish, they can damage the wild fish's prospects of surviving to reproduce. When domesticated fish breed with wild fish, studies indicate the breeding success initially goes up, then slumps as the genetically different offspring are far less successful at returning to the river. Many of the salmon in Norwegian rivers, which used to have fine runs of unusually large fish, are now of farmed origin. Domesticated salmon are also prone to potentially lethal diseases, such as infectious salmon anemia, which has meant many thousands have had to be quarantined or killed. They are also prone to the parasite Gyrodactylus salaris, which has meant that whole river systems in Norway have had to be poisoned with the insecticide rotenone and restocked.

The problem with racial discrimination, though, is not the inference of a person's race from their genetic characteristics. It is quite the opposite: it is the inference of a person's characteristics from their race. The question is not, can you, given an individual's skin color, hair texture, or language, infer something about their ancestry or origin. That is a question of biological systematics -- of lineage, taxonomy, of racial geography, of biological discrimination. Of course you can -- and genomics as vastly refined that inference. You can scan any individual genome and infer rather deep insights about a person's ancestry, or place of origin. But the vastly more controversial question is the converse: Given a racial identity -- African or Asian, say -- can you infer anything about an individual's characteristics: not just skin or hair color, but more complex features, such as intelligence, habits, personality, and aptitude? /I/ Genes can certainly tell us about race, but can race tell us anything about genes? /i/ To answer this question, we need to measure how genetic variation is distributed across various racial categories. Is there more diversity _within_ races or _between_ races? Does knowing that someone is of African versus European descent, say, allow us to refine our understanding of their genetic traits, or their personal, physical, or intellectual attributes in a meaningful manner? Or is there so much variation within Africans and Europeans that _intraracial_ diversity dominates the comparison, thereby making the category "African" or "European" moot? We now know precise and quantitative answers to these questions. A number of studies have tried to quantify the level of genetic diversity of the human genome. The most recent estimates suggest that the vast proportion of genetic diversity (85 to 90 percent) occurs _within_ so-called races (i.e., within Asians or Africans) and only a minor proportion (7 percent) within racial groups (the geneticist Richard Lewontin had estimated a similar distribution as early as 1972). Some genes certainly vary sharply between racial or ethnic groups -- sickle-cell anemia is an Afro-Caribbean and Indian disease, and Tay-Sachs disease has a much higher frequency in Ashkenazi Jews -- but for the most part, the genetic diversity within any racial group dominates the diversity between racial groups -- not marginally, but by an enormous amount. The degree of interracial variability makes "race" a poor surrogate for nearly any feature: in a genetic sense, an African man from Nigria is so "different" from another man from Namibia that it makes little sense to lump them into the same category.

Furthermore, some researchers have suggested a strong association with the presence of the protective gene in populations who have historically farmed yams. To plant yams, farmers clear forests. Cleared forest means more standing water. More standing water means more mosquitoes. More mosquitoes means more malaria—so the idea goes. The emergence of the disease, and as a consequence the resistance gene, may well have been enabled, or at least nurtured, by yam farming. The persistence of sickle cell anemia is the cost of positive selection for resistance against the most destructive disease in our history.

The company takes a strong view against psychotherapy for executives because it denotes unhappiness, and unhappiness is a disgraceful social disease for which there is no excuse or forgiveness. Cancer, pernicious anemia, and diabetes are just fine, and even people with multiple sclerosis and Parkinson's disease may continue to go far in the company until they are no longer allowed to go on at all. But unhappiness is fatal. If my daughter or son were to commit suicide, that would be overlooked, because children do things like that, and that's the way kids are. But if my wife were to jump to her death without a prior record of psychiatric disturbance, did it only because she was unhappy, my chances for further advancement would be over. I'd be ruined.

More food is good, but agricultural diets can provoke mismatch diseases. One of the biggest problems is a loss of nutritional variety and quality. Hunter-gatherers survive because they eat just about anything and everything that is edible. Hunter-gatherers therefore necessarily consume an extremely diverse diet, typically including many dozens of plant species in any given season.26 In contrast, farmers sacrifice quality and diversity for quantity by focusing their efforts on just a few staple crops with high yields. It is likely that more than 50 percent of the calories you consume today derived from rice, corn, wheat, or potatoes. Other crops that have sometimes served as staples for farmers include grains like millet, barley, and rye and starchy roots such as taro and cassava. Staple crops can be grown easily in massive quantities, they are rich in calories, and they can be stored for long periods of time after harvest. One of their chief drawbacks, however, is that they tend to be much less rich in vitamins and minerals than most of the wild plants consumed by hunter-gatherers and other primates.27 Farmers who rely too much on staple crops without supplemental foods such as meat, fruits, and other vegetables (especially legumes) risk nutritional deficiencies. Unlike hunter-gatherers, farmers are susceptible to diseases such as scurvy (from insufficient vitamin C), pellagra (from insufficient vitamin B3), beriberi (from insufficient vitamin B1), goiter (from insufficient iodine), and anemia (from insufficient iron).28 Relying heavily on a few crops—sometimes just one crop—has other serious disadvantages, the biggest being the potential for periodic food shortages and famine. Humans,

While Marie always believed in the importance of X-rays and the healing properties of radium, both she and Pierre suffered radium burns during their experiments; indeed, sometimes the burns were purposeful parts of the experiments. Marie also often carried test tubes of radium in her pockets for convenience. Marie died in 1934 of aplastic anemia, a blood disease associated with radiation exposure. In 1956, Irène died of leukemia, likely from her decades of work with polonium. Frédéric died two years later of liver disease, also likely caused or exacerbated by his long work in radioactivity. The radiation experiments Marie conducted were so intense, and done without protective equipment (because no one yet knew how necessary it would be), that Marie’s notebooks and papers can still be viewed only by people wearing specially purposed protective gear

A True Story Let me tell you about Wendy. For more than ten years, Wendy struggled unsuccessfully with ulcerative colitis. A thirty-six-year-old grade school teacher and mother of three, she lived with constant cramping, diarrhea, and frequent bleeding, necessitating occasional blood transfusions. She endured several colonoscopies and required the use of three prescription medications to manage her disease, including the highly toxic methotrexate, a drug also used in cancer treatment and medical abortions. I met Wendy for an unrelated minor complaint of heart palpitations that proved to be benign, requiring no specific treatment. However, she told me that, because her ulcerative colitis was failing to respond to medications, her gastroenterologist advised colon removal with creation of an ileostomy. This is an artificial orifice for the small intestine (ileum) at the abdominal surface, the sort to which you affix a bag to catch the continually emptying stool. After hearing Wendy’s medical history, I urged her to try wheat elimination. “I really don’t know if it’s going to work,” I told her, “but since you’re facing colon removal and ileostomy, I think you should give it a try.” “But why?” she asked. “I’ve already been tested for celiac and my doctor said I don’t have it.” “Yes, I know. But you’ve got nothing to lose. Try it for four weeks. You’ll know if you’re responding.” Wendy was skeptical but agreed to try. She returned to my office three months later, no ileostomy bag in sight. “What happened?” I asked. “Well, first I lost thirty-eight pounds.” She ran her hand over her abdomen to show me. “And my ulcerative colitis is nearly gone. No more cramps or diarrhea. I’m off everything except my Asacol.” (Asacol is a derivative of aspirin often used to treat ulcerative colitis.) “I really feel great.” In the year since, Wendy has meticulously avoided wheat and gluten and has also eliminated the Asacol, with no return of symptoms. Cured. Yes, cured. No diarrhea, no bleeding, no cramps, no anemia, no more drugs, no ileostomy. So if Wendy’s colitis tested negative for celiac antibodies, but responded to—indeed, was cured by—wheat gluten elimination, what should we label it? Should we call it antibody-negative celiac disease? Antibody-negative wheat intolerance? There is great hazard in trying to pigeonhole conditions such as Wendy’s into something like celiac disease. It nearly caused her to lose her colon and suffer the lifelong health difficulties associated with colon removal, not to mention the embarrassment and inconvenience of wearing an ileostomy bag. There is not yet any neat name to fit conditions such as Wendy’s, despite its extraordinary response to the elimination of wheat gluten. Wendy’s experience highlights the many unknowns in this world of wheat sensitivities, many of which are as devastating as the cure is simple.

Ultimately then, as one gets ready for kundalini awakening, the goal is to help those chakras clear, open, and align. Kundalini will respond with the greatest ease of motion accomplished and will demonstrate how well it knows what to do. As you begin to work through these chakras blockages or energetic reversals, you may find that those struggles look something like this. Blockages for the root chakra may look like low energy, general fear, persistent exhaustion, identity crisis, feeling isolated from the environment, eating disorders, general lack or erratic appetite, blatant materialism, difficulty saving money, or overall constant health problems. For the sacral chakra, blockages or reversals may look like lack of creativity, lack of inspiration, low or no motivation, low or no sexual appetite, feelings of insignificance, feelings of being unloved, feelings of being unaccepted, feelings of being outcasted, inability to care for oneself or persistent and recurrent problems of relationship with one's intimate partners. Blockages may look like identity crises or deficits for the solar plexus chakra, low self-esteem, low or no self-esteem, digestive problems, food intolerance, poor motivation, persistent weakness, constant nausea, anxiety disorders, liver disorder or disease, repeated illnesses, loss of core strength, lack of overall energy, recurrent depression with little relief, feelings of betrayal, For the chakra of the heart, reversals and blockages may seem like the inability to love oneself or others, the inability to put others first, the inability to put oneself first, the inability to overcome a problem ex, constant grudges, confidence issues, social anxiety or intense shyness, the failure to express emotions in a healthy way, problems of commitment, constant procrastination, intense anxiety For the throat chakra, blockages might seem like oversharing, inability to speak truthfully, failure to communicate with others, severe laryngitis, sore throats, respiratory or airway constraints, asthma, anemia, excessive exhaustion, inability to find the right words, paralyzing fear of confusion, nervousness in public situations, sometimes extreme dizziness, physical submissiveness, verba. For the third eye chakra, blockages or reversals might seem like a lack of direction in life, increasingly intense feelings of boredom or stagnation, migraines, insomnia, eye or vision problems, depression, high blood pressure, inability to remember one's dreams, constant and jarring flashbacks, closed-mindedness, fear, history of mental disorders, and history of addiction. For the crown chakra, blockages may look like feelings of envy, extreme sadness, need for superiority over others, self-destructive behaviors, history of addiction, generally harmful habits, dissociations from the physical plane, inability to make even the easiest decisions, persistent exhaustion, terrible migraines, hair loss, anemia, cerebral confusion, poor mental control, lack of intellect.

Now, with all seven of these chakras revolving in the right direction with no blockages whatsoever, your kundalini would not be able to help itself from rising into that state of bliss, which it perceives above. Ultimately then, as one gets ready for kundalini awakening, the goal is to help those chakras clear, open, and align. Kundalini will respond with the greatest ease of motion accomplished and will demonstrate how well it knows what to do. As you begin to work through these chakras blockages or energetic reversals, you may find that those struggles look something like this. Blockages for the root chakra may look like low energy, general fear, persistent exhaustion, identity crisis, feeling isolated from the environment, eating disorders, general lack or erratic appetite, blatant materialism, difficulty saving money, or overall constant health problems. For the sacral chakra, blockages or reversals may look like lack of creativity, lack of inspiration, low or no motivation, low or no sexual appetite, feelings of insignificance, feelings of being unloved, feelings of being unaccepted, feelings of being outcasted, inability to care for oneself or persistent and recurrent problems of relationship with one's intimate partners. Blockages may look like identity crises or deficits for the solar plexus chakra, low self-esteem, low or no self-esteem, digestive problems, food intolerance, poor motivation, persistent weakness, constant nausea, anxiety disorders, liver disorder or disease, repeated illnesses, loss of core strength, lack of overall energy, recurrent depression with little relief, feelings of betrayal, For the chakra of the heart, reversals and blockages may seem like the inability to love oneself or others, the inability to put others first, the inability to put oneself first, the inability to overcome a problem ex, constant grudges, confidence issues, social anxiety or intense shyness, the failure to express emotions in a healthy way, problems of commitment, constant procrastination, intense anxiety For the throat chakra, blockages might seem like oversharing, inability to speak truthfully, failure to communicate with others, severe laryngitis, sore throats, respiratory or airway constraints, asthma, anemia, excessive exhaustion, inability to find the right words, paralyzing fear of confusion, nervousness in public situations, sometimes extreme dizziness, physical submissiveness, verba. For the third eye chakra, blockages or reversals might seem like a lack of direction in life, increasingly intense feelings of boredom or stagnation, migraines, insomnia, eye or vision problems, depression, high blood pressure, inability to remember one's dreams, constant and jarring flashbacks, closed-mindedness, fear, history of mental disorders, and history of addiction. For the crown chakra, blockages may look like feelings of envy, extreme sadness, need for superiority over others, self-destructive behaviors, history of addiction, generally harmful habits, dissociations from the physical plane, inability to make even the easiest decisions, persistent exhaustion, terrible migraines, hair loss, anemia, cerebral confusion, poor mental control, lack of intellect.

Approximately eight hundred skeletons from the Dickson Mounds in the lower Illinois Valley have been analyzed. They reveal a clear picture of the health changes that accompanied the shift from foraging to corn farming around 1200 AD. Archaeologist George Armelagos and his colleagues reported that the farmers’ remains show a 50 percent increase in chronic malnutrition, and three times the incidence of infectious diseases (indicated by bone lesions) compared with the foragers who preceded them. Furthermore, they found evidence of increased infant mortality, delayed skeletal growth in adults, and a fourfold increase in porotic hyperostosis, indicating iron-deficiency anemia in more than half the population.

When James Larrick and his colleagues studied the still relatively isolated Waorani Indians of Ecuador, they found no evidence of hypertension, heart disease, or cancer. No anemia or common cold. No internal parasites. No sign of previous exposure to polio, pneumonia, smallpox, chicken pox, typhus, typhoid, syphilis, tuberculosis, malaria, or serum hepatitis.16 This is not as surprising as it may seem, given that almost all these diseases either originated in domesticated animals or depend upon high-density population for easy transmission. The deadliest infectious diseases and parasites that have plagued our species could not have spread until after the transition to agriculture.

Gluten is associated with cancers of the mouth and throat, esophagus, small intestines, and lymph nodes. It is also associated with type 1 diabetes as well as thyroid disorders, such as Hashimoto’s, the most commonly diagnosed thyroid dysfunction in America. Many patients achieve normalization of their thyroid function only after adopting a gluten-free diet. Gluten sensitivity is also associated with other autoimmune diseases, such as Sjörgens syndrome and dermatitis herpetiformis. Hair loss, or autoimmune alopecia, is another presentation. It is also associated with depression, migraines, arthritis, fatigue, osteoporosis, and anemia, to name a few.

A doctor named John Murray was working with his wife in a Somali refugee camp when he noticed that many of the nomads, despite pervasive anemia and repeated exposure to a range of virulent pathogens, including malaria, tuberculosis, and brucellosis, were free of visible infection. He responded to this anomaly by deciding to treat only part of the population with iron at first. Sure enough, he treated some of the nomads for anemia by giving them iron supplements, and suddenly the infections gained the upper hand. The rate of infection in nomads receiving the extra iron skyrocketed. The Somali nomads weren’t withstanding these infections despite their anemia: they were withstanding these infections because of their anemia. It was iron locking in high gear.

Gluten, a major component of wheat, barley, and rye, is a composite of two different proteins, gliadin and glutelin. Gluten is what gives bread its stretchiness and elasticity, qualities most folks enjoy. But gluten also makes some people seriously ill. It is estimated that about 1 percent of the population is gluten intolerant, though most are unaware of it. If gluten-intolerant individuals eat gluten grains, they develop what’s known as celiac disease. Celiac disease is an autoimmune condition in which the gliadin protein in gluten grains generates an antibody-mediated immune-system attack against the intestines, leading to chronic diarrhea, fatigue, stunting of growth, vitamin and mineral deficiencies, anemia, nerve damage, and osteoporosis. Furthermore, those with celiac disease have higher rates of cancer, schizophrenia, and a whole host of autoimmune illnesses (Jackson et al. 2012; Rubio-Tapia and Murray 2010), suggesting that the body’s response to gluten affects more than just the intestines. And, on the flip side, almost every chronic autoimmune disease we know of is associated with a significantly increased risk of celiac disease (Cosnes et al. 2008; Rousset 2004; Rodrigo et al. 2011; Song and Choi 2004).

While some mainstream medical professionals continue to insist that NCGS doesn’t exist, scientists have validated it as a distinct clinical condition. In one major study, researchers reviewed the charts of 276 patients with irritable bowel syndrome (IBS) who had been diagnosed with NCGS using a double-blind, placebo-controlled wheat challenge (patients were put on a gluten-free diet and then given capsules containing either wheat or an inert substance). As a whole, the NCGS group had a higher frequency of anemia, weight loss, self-reported wheat intolerance, and a history of childhood food allergies than those in the IBS without NCGS group. The authors concluded that their data “confirm the existence of non-celiac

While some mainstream medical professionals continue to insist that NCGS doesn’t exist, scientists have validated it as a distinct clinical condition. In one major study, researchers reviewed the charts of 276 patients with irritable bowel syndrome (IBS) who had been diagnosed with NCGS using a double-blind, placebo-controlled wheat challenge (patients were put on a gluten-free diet and then given capsules containing either wheat or an inert substance). As a whole, the NCGS group had a higher frequency of anemia, weight loss, self-reported wheat intolerance, and a history of childhood food allergies than those in the IBS without NCGS group. The authors concluded that their data “confirm the existence of non-celiac wheat sensitivity as a distinct clinical condition.

Pernicious Anemia translates into fatal blood deficiency, as a century ago it killed many of the people that developed it. It was a horrible and prolonged death process. It was later discovered that feeding raw liver to the patients would treat it. Today the condition is treated with vitamin B12 and iron supplements.

Huge doses of Vitamin B12 had profound beneficial effects on my health.

Although celiac disease is typically thought of as a “gut problem,” more precisely, it is a body-wide inflammatory disease that manifests in the gut. Celiacs, it turns out, can have poor teeth for a couple of reasons. One, gut inflammation can lead to poor absorption of minerals, making the teeth generally weaker and prone to decay. And two, enamel defects commonly seen in celiacs make teeth vulnerable to cavity-forming bacteria. In children, celiac disease often presents as failure to thrive, anemia, digestive symptoms like diarrhea or constipation, or a distinctive rash on the skin. Rosa was too healthy. She had hit every milestone in her development, and her height and weight were above average for her age group. She had no signs or symptoms of anemia, digestive symptoms, or rashes. But in addition to her cavities, she did have another symptom common to celiacs: frequent canker sores.

We have conquered or quelled many diseases that used to kill people in droves: smallpox, measles, polio and the plague. People are taller, and formerly life-threating conditions like appendicitis, dysentery, a broken leg or anemia are easily remedied. To be sure, there is still too much malnutrition and disease in some countries, but these evils are often the result of bad government and social inequality, not a lack of food or medical know how.

The problem is that so little is at stake that there is nothing to which church members can dedicate themselves. "We would do more if we had something to do," may be what the people of the congregation are saying if we just listened. The resulting spiritual anemia is the reason that many churches are so vulnerable to the diseases of dissension, division, and strife. When there is little at stake in a church's ministry, the vacuum will call out the worst side of members.

Mom’s a hypochondriac, too, so the best part was that every week she would get the disease that the medical shows were dramatizing. I’ll never forget, they did an episode on sickle cell anemia, which as far as I know, is almost exclusively an African-American affliction.

Chapter 11 The Vital Force Let’s pretend we are in a make-believe world and that there are 2 people in a room. One is a doctor, the other is a patient. The doctor is color blind but doesn’t know it. The doctor can’t see the color yellow at all. The patient is suffering from a rare disease that has given him chronic headaches, anemia, and has turned his skin completely yellow from head to foot. When the doctor tries to figure out what is going on with the patient, he will completely miss the fact that the patient is yellow. It won’t even register to him. Because of his color blindness that he is completely unaware of, the diagnosis that he makes will be flawed and incomplete, no matter how skilled he is, or how many lab tests he does, Now – in the above pretend scenario, it is possible that the illness that has turned the patient’s skin yellow will have other signs and symptoms that the doctor will discover (like the headaches and anemia), and it is possible that if the doctor treats those symptoms with a medicine that is strong enough, it will impact the patient’s system, and create some result. But because of the doctor’s inherent color blindness, he will be initiating a lopsided treatment, and if anything gets cured, it will be by chance

The girls were dying of a wide range of diseases—pneumonia, anemia, malaria, dysentery—and for two decades no one noticed that the dying children were predominantly those who received the vaccine. The DTP vaccine—while protecting children against diphtheria, tetanus, and pertussis—had ruined their immune systems, making them vulnerable to a wide range of deadly nontarget infections. Mogensen’s team arrived at that conclusion, as had the 1977 Lancet study researchers exactly forty years earlier: “DTP vaccine may kill more children from other causes than it saves from diphtheria, tetanus or pertussis.

the preamble of the National Sickle Cell Anemia Control Act, enacted in 1972 to foster sickle-cell research, screening, counseling, and education, is untrue: “Two million Americans suffer from sickle cell disease.” Actually, 2 million people were healthy carriers22 and fewer than 100,000 Americans suffered from sickle-cell anemia. The erroneous claim coupled with its constantly reinforced perception of sickle-cell disease as a black disorder left Americans with the mistaken impression that a good portion—one in twelve—of African Americans suffered from sickle-cell anemia.

Weeks earlier, we’d had our blood drawn during a med check, and the doctors discovered I carried the Sickle Cell Trait. I didn’t have the disease, Sickle Cell Anemia, but I had the trait, which was believed at the time to increase the risk of sudden, exercise-related death due to cardiac arrest. The Air Force didn’t want me dropping dead in the middle of an evolution and pulled me out of training on a medical.

In 1922, a fourteen-year-old boy with type 1 diabetes was resuscitated from a coma—born anew, as it were—by the infusion of insulin extracted from the pancreatic cells of a dog. In 2010, when Emily Whitehead received her infusion of CAR (chimeric antigen receptor) T cells, or twelve years later, when the first patients with sickle cell anemia are surviving, disease-free, with gene-modified blood stem cells, we are transitioning from the century of the gene to a contiguous, overlapping century of the cell.

Pernicious anemia killed many people before the development of B12 supplements!

Every decade has a unique hematological riddle, and for Minot's era, that riddle was pernicious anemia. Anemia is the deficiency of red blood cells-and its most common form arises from a lack of iron, a crucial nutrient used to build red blood cells. But pernicious anemia, the rare variant that Minot studied, was not caused by iron deficiency (indeed, its name derives from its intransigence to the standard treatment of anemia with iron). By feeding patients increasingly macabre concoctions-half a pound of chicken liver, half-cooked hamburgers, raw hog stomach, and even once the regurgitated gastric juices of one of his students (spiced up with butter, lemon, and parsley)-Minot and his team of researchers conclusively demonstrated in 1926 that pernicious anemia was caused by the lack of a critical micronutrient, a single molecule later identified as vitamin b13. In 1934, Minot and two of his colleagues won the Nobel Prize for this pathbreaking work. Minot had shown that replacing a single molecule could restore the normalcy of blood in this complex hematological disease. Blood was an organ whose activity could be turned on and off by molecular switches.

myeloma is one of the most dreaded cancers. It is practically incurable even with aggressive medical treatment. As myeloma cells take over the bone marrow, healthy white blood cells continue to decline in number, which increases your susceptibility to infection. Reduced levels of red blood cells can lead to anemia, and reduced platelet counts can lead to serious bleeding. Once diagnosed, most people survive fewer than five years.25 Multiple myeloma does not occur out of the blue. It appears to be nearly always preceded by a precancerous

Coincidence? Probably not. Pregnancy isn’t the only time folate is important, of course. A lack of folate is also directly linked to anemia, because folate helps to produce red blood cells.   THE SKIN, AS you’ve probably heard, is the largest organ of the human body. It’s an organ in every sense of the word, responsible for important functions related to the immune system, the nervous system, the circulatory system, and metabolism. The skin protects the body’s stores of folate, and it’s in the skin that a crucial step in the manufacturing of vitamin D takes place.

Well, I believe diseases can be tailored to many genetic variations—to white skin, for example; to the susceptibility to sicklecell anemia …

In this study and others like it, guesswork about a peculiar black predisposition toward unhealthy births imports an old notion about sickle cell disease “afflicting the black race.”25 Whenever I give a talk on this topic, there is inevitably someone in the audience who invokes the mantra that sickle cell anemia is a black genetic disease and therefore proves that race is a genetic category. This misconception was first popularized in the early twentieth century by hematology experts who believed the capacity to develop sickled cells was uniquely inherent in “Negro blood.”26 Stereotypes about black resistance to malaria and susceptibility to sickle cell justified sending black workers to malaria-infested regions in the first part of the century and later led to discriminatory government, employer, and insurance-testing programs in the 1970s.27 The error is easily exposed by looking at two world maps, one highlighting the regions around the globe where malaria is prevalent, the other highlighting areas where sickle cell disease is present. The maps mirror each other perfectly. By comparing them, it is plain to see that malaria and sickle cell aren’t restricted to Africa and that much of Africa is unaffected. High frequencies of the trait also occur in parts of Europe, Oceania, India, and the Middle East, all places where there is malaria. In fact, people in the town of Orchomenos in central Greece have double the rate of sickle cell disease reported among African Americans.28 If frequency of the sickle cell gene determined racial boundaries, it certainly would not prove there is a black race. Instead, as Jared Diamond pointed out in the November 1994 issue of Discover , if we grouped together people by the presence or absence of the sickle cell gene, “we’d place Yemenites, Greeks, New Guineans, Thai, and Dinkas in one ‘race,’ Norwegians and several black African peoples in another.”29 It would be more accurate to call the groups with the sickle cell gene the “antimosquito race.” Of course, that would be a silly way of grouping people, except for studying the sickle cell gene. But “black race” is an equally silly way of grouping people for identifying genetic contributions to disease.

book. Myeloma as a description has its origins with the Greek medical genius Hippocrates, who did the earliest known work on cancer, which he called karkinoma (carcinoma) because the tumors often resembled a crab, karkinos in ancient Greek. In modern descriptions, the condition is complex and treacherous: Plasma cells in the bone marrow become malignant and produce tumors, causing destruction of the bone and resulting in pathologic fracture and pain. A secretory form of the disease is characterized by the presence of Bence-Jones protein, a monoclonal immunoglobulin, which can cause anemia and kidney disease