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Keep testing your blood and urine every 2 months and adjust your doses accordingly. If the tests reveal your kidneys are working well and your calcium metabolism is within the reference range, the next step will be to look at your PTH levels: · If PTH levels are below the lowest reference value, you’ll need to reduce the vitamin D you are taking. · If PTH levels are at the lowest value, but still within the reference range, you’ll need to maintain the same dose of vitamin D you have been taking. · If PTH is within the reference range, but not yet at the lowest value, it’s time to increase vitamin D supplementation. This is, by far, the most common scenario. You may increase doses by 10,000 IU or by 20,000 IU, or more, depending on how far away from our goal you are.
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Tiago Henriques (How Not To Die With True High-Dose Vitamin D Therapy: Coimbra’s Protocol and the Secrets of Safe High-Dose Vitamin D3 and Vitamin K2 Supplementation)