Scientific Advancement Quotes

The greater the scientific advance, the more primitive the fear.

You live in a deranged age - more deranged than usual, because despite great scientific and technological advances, man has not the faintest idea of who he is or what he is doing.

A number of years ago, when I was a freshly-appointed instructor, I met, for the first time, a certain eminent historian of science. At the time I could only regard him with tolerant condescension. I was sorry of the man who, it seemed to me, was forced to hover about the edges of science. He was compelled to shiver endlessly in the outskirts, getting only feeble warmth from the distant sun of science- in-progress; while I, just beginning my research, was bathed in the heady liquid heat up at the very center of the glow. In a lifetime of being wrong at many a point, I was never more wrong. It was I, not he, who was wandering in the periphery. It was he, not I, who lived in the blaze. I had fallen victim to the fallacy of the 'growing edge;' the belief that only the very frontier of scientific advance counted; that everything that had been left behind by that advance was faded and dead. But is that true? Because a tree in spring buds and comes greenly into leaf, are those leaves therefore the tree? If the newborn twigs and their leaves were all that existed, they would form a vague halo of green suspended in mid-air, but surely that is not the tree. The leaves, by themselves, are no more than trivial fluttering decoration. It is the trunk and limbs that give the tree its grandeur and the leaves themselves their meaning. There is not a discovery in science, however revolutionary, however sparkling with insight, that does not arise out of what went before. 'If I have seen further than other men,' said Isaac Newton, 'it is because I have stood on the shoulders of giants.

The scientific man does not aim at an immediate result. He does not expect that his advanced ideas will be readily taken up. His work is like that of the planter — for the future. His duty is to lay the foundation for those who are to come, and point the way. He lives and labors and hopes.

[Flaubert] didn’t just hate the railway as such; he hated the way it flattered people with the illusion of progress. What was the point of scientific advance without moral advance? The railway would merely permit more people to move about, meet and be stupid together.

Reading list (1972 edition)[edit] 1. Homer – Iliad, Odyssey 2. The Old Testament 3. Aeschylus – Tragedies 4. Sophocles – Tragedies 5. Herodotus – Histories 6. Euripides – Tragedies 7. Thucydides – History of the Peloponnesian War 8. Hippocrates – Medical Writings 9. Aristophanes – Comedies 10. Plato – Dialogues 11. Aristotle – Works 12. Epicurus – Letter to Herodotus; Letter to Menoecus 13. Euclid – Elements 14. Archimedes – Works 15. Apollonius of Perga – Conic Sections 16. Cicero – Works 17. Lucretius – On the Nature of Things 18. Virgil – Works 19. Horace – Works 20. Livy – History of Rome 21. Ovid – Works 22. Plutarch – Parallel Lives; Moralia 23. Tacitus – Histories; Annals; Agricola Germania 24. Nicomachus of Gerasa – Introduction to Arithmetic 25. Epictetus – Discourses; Encheiridion 26. Ptolemy – Almagest 27. Lucian – Works 28. Marcus Aurelius – Meditations 29. Galen – On the Natural Faculties 30. The New Testament 31. Plotinus – The Enneads 32. St. Augustine – On the Teacher; Confessions; City of God; On Christian Doctrine 33. The Song of Roland 34. The Nibelungenlied 35. The Saga of Burnt Njál 36. St. Thomas Aquinas – Summa Theologica 37. Dante Alighieri – The Divine Comedy;The New Life; On Monarchy 38. Geoffrey Chaucer – Troilus and Criseyde; The Canterbury Tales 39. Leonardo da Vinci – Notebooks 40. Niccolò Machiavelli – The Prince; Discourses on the First Ten Books of Livy 41. Desiderius Erasmus – The Praise of Folly 42. Nicolaus Copernicus – On the Revolutions of the Heavenly Spheres 43. Thomas More – Utopia 44. Martin Luther – Table Talk; Three Treatises 45. François Rabelais – Gargantua and Pantagruel 46. John Calvin – Institutes of the Christian Religion 47. Michel de Montaigne – Essays 48. William Gilbert – On the Loadstone and Magnetic Bodies 49. Miguel de Cervantes – Don Quixote 50. Edmund Spenser – Prothalamion; The Faerie Queene 51. Francis Bacon – Essays; Advancement of Learning; Novum Organum, New Atlantis 52. William Shakespeare – Poetry and Plays 53. Galileo Galilei – Starry Messenger; Dialogues Concerning Two New Sciences 54. Johannes Kepler – Epitome of Copernican Astronomy; Concerning the Harmonies of the World 55. William Harvey – On the Motion of the Heart and Blood in Animals; On the Circulation of the Blood; On the Generation of Animals 56. Thomas Hobbes – Leviathan 57. René Descartes – Rules for the Direction of the Mind; Discourse on the Method; Geometry; Meditations on First Philosophy 58. John Milton – Works 59. Molière – Comedies 60. Blaise Pascal – The Provincial Letters; Pensees; Scientific Treatises 61. Christiaan Huygens – Treatise on Light 62. Benedict de Spinoza – Ethics 63. John Locke – Letter Concerning Toleration; Of Civil Government; Essay Concerning Human Understanding;Thoughts Concerning Education 64. Jean Baptiste Racine – Tragedies 65. Isaac Newton – Mathematical Principles of Natural Philosophy; Optics 66. Gottfried Wilhelm Leibniz – Discourse on Metaphysics; New Essays Concerning Human Understanding;Monadology 67. Daniel Defoe – Robinson Crusoe 68. Jonathan Swift – A Tale of a Tub; Journal to Stella; Gulliver's Travels; A Modest Proposal 69. William Congreve – The Way of the World 70. George Berkeley – Principles of Human Knowledge 71. Alexander Pope – Essay on Criticism; Rape of the Lock; Essay on Man 72. Charles de Secondat, baron de Montesquieu – Persian Letters; Spirit of Laws 73. Voltaire – Letters on the English; Candide; Philosophical Dictionary 74. Henry Fielding – Joseph Andrews; Tom Jones 75. Samuel Johnson – The Vanity of Human Wishes; Dictionary; Rasselas; The Lives of the Poets

The scientific man does not aim at an immediate result. He does not expect that his advanced ideas will be readily taken up. His work is like that of the planter—for the future. His duty is to lay the foundation for those who are to come, and point the way.

It is not a dream, it is a simple feat of scientific electrical engineering, only expensive — blind, faint-hearted, doubting world! [...] Humanity is not yet sufficiently advanced to be willingly led by the discoverer's keen searching sense. But who knows? Perhaps it is better in this present world of ours that a revolutionary idea or invention instead of being helped and patted, be hampered and ill-treated in its adolescence — by want of means, by selfish interest, pedantry, stupidity and ignorance; that it be attacked and stifled; that it pass through bitter trials and tribulations, through the strife of commercial existence. So do we get our light. So all that was great in the past was ridiculed, condemned, combatted, suppressed — only to emerge all the more powerfully, all the more triumphantly from the struggle." – Nikola Tesla (at the end of his dream for Wardenclyffe)

Our scientific advances will be merely obscene unless they help the large part of our world's population emerge from miserable uncertainty and debilitating terror.

The truth is,” Olive said, behind a lectern in Paris, “even now, all these centuries later, for all our technological advances, all our scientific knowledge of illness, we still don’t always know why one person gets sick and another doesn’t, or why one patient survives and another dies. Illness frightens us because it’s chaotic. There’s an awful randomness about it.

Science, however, is never conducted as a popularity contest, but instead advances through testable, reproducible, and falsifiable theories.

We are chained hand and foot by protocol, enslaved to a static, empty world where men and women can’t read, where the scientific advances of the ages are the preserve of the rich, where artists and poets are doomed to endless repetitions and sterile reworking of past masterpieces. Nothing is new. New does not exist. Nothing changes, nothing grows, evolves, develops. Time has stopped. Progress is forbidden

Society never advances. It recedes as fast on one side as it gains on the other. It undergoes continual changes; it is barbarous, it is civilized, it is christianized, it is rich, it is scientific; but this change is not amelioration. For every thing that is given, something is taken.

America's abundance was created not by public sacrifices to the common good, but by the productive genius of free men who pursued their own personal interests and the making of their own private fortunes. They did not starve the people to pay for America's industrialization. They gave the people better jobs, higher wages, and cheaper goods with every new machine they invented, with every scientific discovery or technological advance- and thus the whole country was moving forward and profiting, not suffering, every step of the way.

There are times when the marvels of scientific advancement expedite our processes, making our lives easier. Modern technology provides machines that can think three or five or seven steps ahead of the human mind, machines that offer elegant solutions, a selection of contingency plans, Bs and Cs and Ds in case A isn't to your liking. And then there are times when a screwdriver and a bit of elbow grease are all that's necessary to get the job done.

Whereas a novice makes moves until he gets checkmated (proof), a Grand Master realizes 20 moves in advance that it’s futile to continue playing (conceptualizing).

Concepts that have proven useful in ordering things easily achieve such authority over us that we forget their earthly origins and accept them as unalterable givens. Thus they come to be stamped as “necessities of thought”, “a priori givens”, etc. The path of scientific advance is often made impassable for a long time through such errors. For that reason, it is by no means an idle game if we become practiced in analyzing the long commonplace concepts and exhibiting those circumstances upon which their justification and usefulness depend, how they have grown up, individually, out of the givens of experience. By this means, their all-too-great authority will be broken. They will be removed if they cannot be properly legitimated, corrected if their correlation with given things be far too superfluous, replaced by others if a new system can be established that we prefer for whatever reason.

What was the point of scientific advance without moral advance? The railway would merely permit more people to move about, meet and be stupid together

When asked whether or not we are Marxists, our position is the same as that of a physicist, when asked if he is a “Newtonian” or of a biologist when asked if he is a “Pasteurian.” There are truths so evident, so much a part of the peoples’ knowledge, that it is now useless to debate them. One should be a “Marxist” with the same naturalness with which one is a “Newtonian” in physics or a “Pasteurian.” If new facts bring about new concepts, the latter will never take away that portion of truth possessed by those that have come before. Such is the case, for example, of “Einsteinian” relativity or of Planck’s quantum theory in relation to Newton’s discoveries. They take absolutely nothing away from the greatness of the learned Englishman. Thanks to Newton, physics was able to advance until it achieved new concepts of space. The learned Englishman was the necessary stepping-stone for that. Obviously, one can point to certain mistakes of Marx, as a thinker and as an investigator of the social doctrines and of the capitalist system in which he lived. We Latin Americans, for example, cannot agree with his interpretation of Bolivar, or with his and Engels’ analysis of the Mexicans, which accepted as fact certain theories of race or nationality that are unacceptable today. But the great men who discover brilliant truths live on despite their small faults and these faults serve only to show us they were human. That is to say, they were human beings who could make mistakes, even given the high level of consciousness achieved by these giants of human thought. This is why we recognize the essential truths of Marxism as part of humanity’s body of cultural and scientific knowledge. We accept it with the naturalness of something that requires no further argument.

America’s forefathers had a vision of a spiritually enlightened utopia, in which freedom of thought, education of the masses, and scientific advancement would replace the darkness of outdated religious superstition.

Modern life seems to recede further and further away from nature, and closely connected with this fact we seem to be losing the feeling of reverence towards nature. It is probably inevitable when science and machinery, capitalism and materialism go hand in hand so far in a most remarkably successful manner. Mysticism, which is the life of religion in whatever sense we understand it, has come to be relegated altogether in the background. Without a certain amount of mysticism there is no appreciation for the feeling of reverence, and, along with it, for the spiritual significance of humility. Science and scientific technique have done a great deal for humanity; but as far as our spiritual welfare is concerned we have not made any advances over that attained by our forefathers. In fact we are suffering at present the worst kind of unrest all over the world.

Without us, Earth’s geology will grind on. Winds and rain and blowing sand will dissolve and bury the artifacts of our civilization. Human-caused climate change will probably delay the start of the next glaciation, but we haven’t ended the cycle of ice ages. Eventually, the glaciers will advance again. A million years from now, few human artifacts will remain.

But anyone who is practically acquainted with scientific work is aware that those who refuse to go beyond fact, rarely get as far as fact; and anyone who has studied the history of science knows that almost every great step therein has been made by the 'anticipation of Nature,' that is, by the invention of hypotheses, which, though verifiable, often had very little foundation to start with.

...where were answers to the truly deep questions? Religion promised those, though always in vague terms, while retreating from one line in the sand to the next. Don't look past this boundary, they told Galileo, then Hutton, Darwin, Von Neumann, and Crick, always retreating with great dignity before the latest scientific advance, then drawing the next holy perimeter at the shadowy rim of knowledge.

I have been doomed to such a dreadful shipwreck: that man is not truly one, but truly two. I say two, because the state of my own knowledge does not pass beyond that point. Others will follow, others will outstrip me on the same lines; and I hazard the guess that man will be ultimately known for a mere polity of multifarious, incongruous and independent denizens. I, for my part, from the nature of my life, advanced infallibly in one direction and in one direction only. It was on the moral side, and in my own person, that I learned to recognise the thorough and primitive duality of man; I saw that, of the two natures that contended in the field of my consciousness, even if I could rightly be said to be either, it was only because I was radically both; and from an early date, even before the course of my scientific discoveries had begun to suggest the most naked possibility of such a miracle, I had learned to dwell with pleasure, as a beloved daydream, on the thought of the separation of these elements. If each, I told myself, could be housed in separate identities, life would be relieved of all that was unbearable; the unjust might go his way, delivered from the aspirations and remorse of his more upright twin; and the just could walk steadfastly and securely on his upward path, doing the good things in which he found his pleasure, and no longer exposed to disgrace and penitence by the hands of this extraneous evil. It was the curse of mankind that these incongruous faggots were thus bound together—that in the agonised womb of consciousness, these polar twins should be continuously struggling. How, then were they dissociated?

There were other thinkers, Bowman also found, who held even more exotic views. They did not believe that really advanced beings would possess organic bodies at all. Sooner or later, as their scientific knowledge progressed, they would get rid of the fragile, disease-and-accident-prone homes that Nature had given them, and which doomed them to inevitable death. They would replace their natural bodies as they wore out—or perhaps even before that—by constructions of metal and plastic, and would thus achieve immortality.

I felt vaguely outraged that such a bad person had such a good car. Because the car was the culmination of a thousand-odd years of scientific advancement. But the guy was a dick. I wondered when that had happened; that we had started making better machines than people.

Scientific knowledge advances haltingly and is stimulated by contention and doubt.

All kinds of mysterious phenomena exist in this world, but answers to most of them have come with advances in scientific knowledge. Love is the sole holdout-nothing can explain it. A Chinese writer by the name of Ah Cheng wrote that love is just a chemical reaction, an unconventional point of view that seemed quite fresh at the time. But if love can be controlled and initiated by means of chemistry, then novelists would be out of a job. So while he may have had his finger on the truth, I'll remain a member of the loyal opposition.

Scientific advancement carries risk. It always has. Space programs, genetic research, medicine—they all make mistakes. Science needs to survive its own blunders, at any cost. For everyone’s sake.

Man’s conquest of Nature, if the dreams of some scientific planners are realized, means the rule of a few hundreds of men over billions upon billions of men. There neither is nor can be any simple increase of power on Man’s side. Each new power won by man is a power over man as well. Each advance leaves him weaker as well as stronger. In every victory, besides being the general who triumphs, he is also the prisoner who follows the triumphal car.

Why does the universe go to all the bother of existing? Is the unified theory so compelling that it brings about its own existence? Or does it need a creator, and, if so, does he have any other effect on the universe? And who created him?....Up to now, most scientists have been too occupied with the development of new theories that describe what the universe is to ask the question why. On the other hand, the people whose business it is to ask why, the philosophers, have not been able to keep up with the advance of scientific theories....However, if we do discover a complete theory, it should in time be understandable in broad principle by everyone, not just a few scientists. Then we shall all, philosophers, scientists, and just ordinary people, be able to take part in the discussion of the question of why it is that we and the universe exist. If we find the answer to that, it would be the ultimate triumph of human reason--for then we would know the mind of God.

Every advance [in Science] will most likely tell us as much about ourselves as it will about the universe we inhabit. We are all collections of chemicals made in the cataclysmic explosions of stars; we are stardust, or nuclear waste, depending on your perspective.

With the idol of certainty (including that of degrees of imperfect certainty or probability) there falls one of the defences of obscurantism which bar the way of scientific advance. For the worship of this idol hampers not only the boldness of our questions, but also the rigour and the integrity of our tests. The wrong view of science betrays itself in the craving to be right; for it is not his possession of knowledge, of irrefutable truth, that makes the man of science, but his persistent and recklessly critical quest for truth.

The Age of Intellect is accompanied by surprising advances in natural science. In the ninth century, for example, in the age of Mamun, the Arabs measured the circumference of the earth with remarkable accuracy. Seven centuries were to pass before Western Europe discovered that the world was not flat. Less than fifty years after the amazing scientific discoveries under Mamun, the Arab Empire collapsed. Wonderful and beneficent as was the progress of science, it did not save the empire from chaos.

The very word "secrecy" is repugnant in a free and open society; and we are as a people inherently and historically opposed to secret societies, to secret oaths and to secret proceedings...Our way of life is under attack. Those who make themselves our enemy are advancing around the globe...no war ever posed a greater threat to our security. If you are awaiting a finding of "clear and present danger," then I can only say that the danger has never been more clear and its presence has never been more imminent...For we are opposed around the world by a monolithic and ruthless conspiracy that relies primarily on covert means for expanding its sphere of influence–on infiltration instead of invasion, on subversion instead of elections, on intimidation instead of free choice, on guerrillas by night instead of armies by day. It is a system which has conscripted vast human and material resources into the building of a tightly knit, highly efficient machine that combines military, diplomatic, intelligence, economic, scientific and political operations. Its preparations are concealed, not published. Its mistakes are buried, not headlined. Its dissenters are silenced, not praised. No expenditure is questioned, no rumor is printed, no secret is revealed.

Kovacs to a female believer in New Revelation: "..I’m calling you a gutless betrayer of your sex. I can see your husband’s angle, he’s a man, he’s got everything to gain from this crapshit. But you? You’ve thrown away centuries of political struggle and scientific advance so you can sit in the dark and mutter your superstitions of unworth to yourself. You’ll let your life, the most precious thing you have, be stolen from you hour by hour and day by day as long as you can eke out the existence your males will let you have. And then, when you finally die, and I hope it’s soon, sister, I really do, then at the last you’ll spite your own potential and shirk the final power we’ve won for ourselves to come back and try again. You’ll do all of this because of your fucking faith, and if that child in your belly is female, then you’ll condemn her to the same fucking thing

As science advances, there seems to be less and less for God to do. It's a big universe, of course, so He, She, or It, could be profitably employed in many places. But what has clearly been happening is that evolving before our eyes has been a God of the Gaps; that is, whatever it is we cannot explain lately is attributed to God. And then after a while, we explain it, and so that's no longer God's realm.

He alienated his friends in the sciences by thanking them extravagantly for scientific advances he had read about in the recent newspapers and magazines, by assuring them, with a perfectly straight face, that life was getting better and better, thanks to scientific thinking.

One of the difficulties in raising public concern over the very severe threats of global warming is that 40 percent of the US population does not see why it is a problem, since Christ is returning in a few decades. About the same percentage believe that the world was created a few thousand years ago. If science conflicts with the Bible, so much the worse for science. It would be hard to find an analogue in other societies.

Man’s awesome scientific advances into the infinitude of space as well as the infinitude of sub-atomic particles seems most likely to lead to the total destruction of our world unless we can make great advances in understanding and dealing with interpersonal and inter-group tensions. I

It is rather ironical that in the sixteenth century some people resisted advances in science because they seemed to threaten belief in God; whereas in the twentieth century scientific ideas of a beginning have been resisted because they threatened to increase the plausibility of belief in God.

scientific knowledge is advanced by the systematic criticism and purging of what currently passes for knowledge, so in religion too we need to criticize and expel all the illusory and dysfunctional religious material we have inherited.

Scientific advancement carries risk,” Kohler argued. “It always has. Space programs, genetic research, medicine—they all make mistakes. Science needs to survive its own blunders, at any cost. For everyone’s sake.” Vittoria was amazed at Kohler’s ability to weigh moral issues with scientific detachment. His intellect seemed to be the product of an icy divorce from his inner spirit. “You think CERN is so critical to the earth’s future that we should be immune from moral responsibility?

...this 'fecundity of will,' this thirst for action, when accompanied by poverty of feeling and intellect incapable of creation, will produce nothing but a Napoleon I or a Bismarck, wiseacres who try to force the world to progress backwards. While on the other hand, mental fertility destitute of well developed sensibility will bring forth such barren fruits as literary and scientific pedants who only hinder the advance of knowledge. Finally, sensibility unguided by large intelligence will produce such persons as the woman ready to sacrifice everything for some brute of a man, upon whom she pours forth all her love. If life is to be fruitful, it must be so at once in intelligence, in feeling and in will. This fertility in every direction is life; the only thing worthy the name.

The cost of scientific advance is the humbling recognition that reality was not constructed to be easily grasped by the human mind. This is the cardinal tenet of scientific understanding: Our species and its ways of thinking are a product of evolution, not the purpose of evolution.

Radical space technologies never reach the public because unknown groups do not wish humanity to have access to the highest knowledge or the most advanced scientific inventions. Perhaps this suppression is out of fear that the masses may be able to explore our Solar System and the Universe beyond it. Whatever the case, it seems they want us to stay at ignorant levels forever.

Today the guns are silent. A great tragedy has ended. A great victory has been won... A new era is upon us. Even the lesson of victory itself brings with it profound concern, both for our future security and the survival of civilization. The destructiveness of the war potential, through progressive advances in scientific discovery, has in fact now reached a point which revises the traditional concepts of war. Men since the beginning of time have sought peace... Military alliances, balances of power, leagues of nations, all in turn have failed, leaving the only path to be by way of the crucible of war. We have had our last chance. If we do not now devise some greater and more equitable system, Armageddon will be at our door. The problem basically is theological and involves a spiritual recrudescence and improvement of human character that will synchronize with our matchless advances in science, art, literature and all material and cultural developments of the past two thousand years. It must be of the spirit if we are to save the flesh.

Society never advances. It recedes as fast on one side as it gains on the other. It undergoes continual changes; it is barbarous, it is civilized, it is christianized, it is rich, it is scientific; but this change is not amelioration. For every thing that is given, something is taken. Society acquires new arts, and loses old instincts. What a contrast between the well-clad, reading, writing, thinking American, with a watch, a pencil, and a bill of exchange in his pocket, and the naked New Zealander, whose property is a club, a spear, a mat, and an undivided twentieth of a shed to sleep under! But compare the health of the two men, and you shall see that the white man has lost his aboriginal strength. If the traveller tell us truly, strike the savage with a broad axe, and in a day or two the flesh shall unite and heal as if you struck the blow into soft pitch, and the same blow shall send the white to his grave. The civilized man has built a coach, but has lost the use of his feet. He is supported on crutches, but lacks so much support of muscle. He has a fine Geneva watch, but he fails of the skill to tell the hour by the sun. A Greenwich nautical almanac he has, and so being sure of the information when he wants it, the man in the street does not know a star in the sky. The solstice he does not observe; the equinox he knows as little; and the whole bright calendar of the year is without a dial in his mind. His note-books impair his memory; his libraries overload his wit; the insurance-office increases the number of accidents; and it may be a question whether machinery does not encumber; whether we have not lost by refinement some energy, by a Christianity entrenched in establishments and forms, some vigor of wild virtue. For every Stoic was a Stoic; but in Christendom where is the Christian?

This was the pivotal insight of the Scientific Revolution: that the advancement of knowledge depends on current theories collapsing in the face of new insights and discoveries. In this model of progress, errors do not lead us away from the truth. Instead, they edge us incrementally toward it.

Pseudoscience is almost always recognizable from a distance, and easy to confirm on close examination. Science is, however, not immune from hubris, and bad science can be tougher to spot. Those of us who make a living from science or science media must display scientific integrity. We must constantly test our assumptions and fight the siren song of consensus when our data tells us to be contrarian. We must remain independent of political or religious bias in evaluating our work. We must admit when we are wrong, and remain willing to evolve when verifiable data demands change. We must admit when we are uncertain, remain humble in advances, and offer courageous and independent advice grounded in science.

Nonetheless, a movement within the American political right, heavily underwritten by fossil fuel interests, has prosecuted a fanatical and mendacious campaign to deny that greenhouse gases are warming the planet.47 In doing so they have advanced the conspiracy theory that the scientific community is fatally infected with political correctness and ideologically committed to a government takeover of the economy.

Today, nothing is unusual about a scientific discovery's being followed soon after by a technical application: The discovery of electrons led to electronics; fission led to nuclear energy. But before the 1880's, science played almost no role in the advances of technology. For example, James Watt developed the first efficient steam engine long before science established the equivalence between mechanical heat and energy.

As a theoretical physicist Max Planck (1858-1947) noted, "A new scientific truth does not triumph by convincing its opponents and making them see the light, but rather because its opponents eventually die, and a new generation grows up that is familiar with it." In other words, science advances by a series of funerals.

The Greek culture of the Sophists had developed out of all the Greek instincts; it belongs to the culture of the Periclean age as necessarily as Plato does not: it has its predecessors in Heraclitus, in Democritus, in the scientific types of the old philosophy; it finds expression in, e.g., the high culture of Thucydides. And – it has ultimately shown itself to be right: every advance in epistemological and moral knowledge has reinstated the Sophists – Our contemporary way of thinking is to a great extent Heraclitean, Democritean, and Protagorean: it suffices to say it is Protagorean, because Protagoras represented a synthesis of Heraclitus and Democritus.

The scientific world view works so well, explains so much and resonates so harmoniously with the most advanced parts of our brains that in time, I think, virtually every culture on the Earth, left to its own devices, would have discovered science. Some culture had to be first. As it turned out, Ionia was the place where science was born.

The level of public education in science and technology is an important sign of the national scientific accomplishment. It is a matter of overall importance in economic development, scientific advance, and the progress of society.

But America, as I look at you from afar, I wonder whether your moral and spiritual progress has been commensurate with your scientific progress. It seems to me that your moral progress lags behind your scientific progress. Your poet Thoreau used to talk about “improved means to an unimproved end.” How often this is true. You have allowed the material means by which you live to outdistance the spiritual ends for which you live. You have allowed your mentality to outrun your morality. You have allowed your civilization to outdistance your culture. Through your scientific genius you have made of the world a neighborhood, but through your moral and spiritual genius you have failed to make of it a brotherhood. So America, I would urge you to keep your moral advances abreast with your scientific advances.

Science is a field which grows continuously with ever expanding frontiers. Further, it is truly international in scope. Any particular advance has been preceded by the contributions of those from many lands who have set firm foundations for further developments. The Nobel awards should be regarded as giving recognition to this general scientific progress as well as to the individuals involved. Further, science is a collaborative effort. The combined results of several people working together is often much more effective than could be that of an individual scientist working alone.

the genes of modern-day Africans are a treasure house for all humanity. They possess our species’ greatest reservoir of genetic diversity, of which further study will shed new light on the heredity of the human body and mind. Perhaps the time has come, in light of this and other advances in human genetics, to adopt a new ethic of racial and hereditary variation, one that places value on the whole of diversity rather than on the differences composing the diversity. It would give proper measure to our species’ genetic variation as an asset, prized for the adaptability it provides all of us during an increasingly uncertain future. Humanity is strengthened by a broad portfolio of genes that can generate new talents, additional resistance to diseases, and perhaps even new ways of seeing reality. For scientific as well as for moral reasons, we should learn to promote human biological diversity for its own sake instead of using it to justify prejudice and conflict.

Yet there was also something slightly spooky about them. Norton could never understand how men with advanced scientific and technical training could possibly believe some of the things he had heard Cosmo Christers state as incontrovertible fact.

Where there were once several competing approaches to medicine, there is now only one that matters to most hospitals, insurers, and the vast majority of the public. One that has been shaped to a great degree by the successful development of potent cures that followed the discovery of sulfa drugs. Aspiring caregivers today are chosen as much (or more) for their scientific abilities, their talent for mastering these manifold technological and pharmaceutical advances as for their interpersonal skills. A century ago most physicians were careful, conservative observers who provided comfort to patients and their families. Today they act: They prescribe, they treat, they cure. They routinely perform what were once considered miracles. The result, in the view of some, has been a shift in the profession from caregiver to technician. The powerful new drugs changed how care was given as well as who gave it.

My friends, don’t get me wrong, our forefathers were deeply religious men, but they were Deists—men who believed in God, but in a universal and open-minded way. The only religious ideal they put forth was religious freedom.” He pulled the microphone from the podium and strode out to the edge of the stage. “America’s forefathers had a vision of a spiritually enlightened utopia, in which freedom of thought, education of the masses, and scientific advancement would replace the darkness of outdated religious superstition.

Why does the universe go to all the bother of existing? Is the unified theory so compelling that it brings about its own existence? Or does it need a creator, and, if so, does he have any other effect on the universe? And who created him? Up to now, most scientists have been too occupied with the development of new theories that describe what the universe is to ask the question why. On the other hand, the people whose business it is to ask why, the philosophers, have not been able to keep up with the advance of scientific theories. In the eighteenth century, philosophers considered the whole of human knowledge, including science, to be their field and discussed questions such as: Did the universe have a beginning? However, in the nineteenth and twentieth centuries, science became too technical and mathematical for the philosophers, or anyone else except a few specialists. Philosophers reduced the scope of their inquiries so much that Wittgenstein, the most famous philosopher of this century, said, 'The sole remaining task for philosophy is the analysis of language.' What a comedown from the great tradition of philosophy from Aristotle to Kant! However, if we do discover a complete theory, it should in time be understandable in broad principle by everyone, not just a few scientists. Then we shall all, philosophers, scientists, and just ordinary people, be able to take part in the discussion of the question of why it is that we and the universe exist. If we find the answer to that, it would be the ultimate triumph of human reason--for then we would know the mind of God.

Liebig was not a teacher in the ordinary sense of the word. Scientifically productive himself in an unusual degree, and rich in chemical ideas, he imparted the latter to his advanced pupils, to be put by them to experimental proof; he thus brought his pupils gradually to think for themselves, besides showing and explaining to them the methods by which chemical problems might be solved experimentally.

I. When a distinguished but elderly scientist states that something is possible, he is almost certainly right. When he states that something is impossible, he is very probably wrong. II. The only way of discovering the limits of the possible is to venture a little way past them into the impossible. III. Any sufficiently advanced technology is indistinguishable from magic. —ARTHUR C. CLARKE’S THREE LAWS

Brain Research Through Advancing Innovative Neurotechnologies (or BRAIN) project announced by President Obama, and the Human Brain Project of the European Union, which will potentially allocate billions of dollars to decode the pathways of the brain, all the way down to the neural level.

If you turn to a branch of those sciences that try to give a solution to the questions of life--to physiology, psychology, biology, sociology--there you will find an astounding poverty of thought, a very great lack of clarity, completely unjustified claims to answer questions that lie outside their subject and never-ending contradictions between one thinker and others, and even within himself. If you turn to a branch of the sciences that is not concerned with solving the questions of life but answers its own scientific, specialized questions, then you are captivated by the power of human intellect but you know in advance that there are no answers to the questions of life. These sciences directly ignore the questions of life. They say, "We have no answers to 'What are you?' and 'Why do you live?' and are not concerned with this; but if you need to know the laws of light, of chemical compounds, the laws of the development of organisms, if you need to know the laws of bodies and their forms and the relation of numbers and quantities, if you need to know the laws of your own mind, to all that we have clear, precise, and unquestionable answers.

All scientific work is incomplete—whether it be observational or experimental. All scientific work is liable to be upset or modified by advancing knowledge. That does not confer upon us a freedom to ignore the knowledge we already have, to postpone action that it appears to demand at a given time. Who knows, asks Robert Browning, but the world may end tonight? True, but on available evidence most of us make ready to commute on the 8:30 next day.9

Arthur C. Clarke once remarked that 'any sufficiently advanced technology is indistinguishable from magic'. This is true, but slightly misleading. It is stated from the point of view of a pre-scientific thinker, which is the wrong way round. The fact is that to anyone who understands what virtual reality is, even genuine magic would be indistinguishable from technology, for there is no room for magic in a comprehensible reality. Anything that seems incomprehensible is regarded by science merely as evidence that there is something we have not yet understood, be it a conjuring trick, advanced technology or a new law of physics.

It is a fact of life that oversimplified accounts of the development of science are often necessary in its teaching. Most scientific progress is a messy, complex and slow process; only with the hindsight of an overall understanding of a phenomenon can a story be told pedagogically rather than chronologically. This necessitates the distilling of certain events and personalities from the melee: those who are deemed to have made the most important contributions. It is inevitable therefore that the many smaller or less important advances scattered randomly across hundreds of years of scientific history tend to be swept up like autumn leaves into neat piles, on top of which sit larger-than-life personalities credited with taking a discipline forward in a single jump. Sometimes this is perfectly valid, and one cannot deny the genius of an Aristotle, a Newton, a Darwin or an Einstein. But it often leaves behind forgotten geniuses and unsung heroes.

It was sort of amazing seeing men who weren't particularly attractive but who believed, more or less correctly, that they could have and do whatever they wanted. I was always calculating with scientific precision the relative beauty of the people I wanted to be with, and would steer clear of the ones who exceeded me too greatly. But then you'd see guys like this one trundling around the world, reaching out, cheerily thoughtless, for whatever shiny thing passed. They didn't feel the need to strike an equitable bargain, they just advanced towards you, grinning a little sheepishly maybe, and their entitlement was so alien and enviable that it was something like charming.

While Europe was mired in its dark years of medieval superstition, the work of combining theory and experiment was advanced primarily in the Islamic world. Muslim scientists often also worked as scientific instrument makers, which made them experts at measurements and applying theories. The Arab physicist Ibn al-Haytham, known as Alhazen, wrote a seminal text on optics in 1021 that combined observations and experiments to develop a theory of how human vision works, then devised further experiments to test the theory.

Science is an inherent contradiction — systematic wonder — applied to the natural world. In its mundane form, the methodical instinct prevails and the result, an orderly procession of papers, advances the perimeter of knowledge, step by laborious step. Great scientific minds partake of that daily discipline and can also suspend it, yielding to the sheer love of allowing the mental engine to spin free. And then Einstein imagines himself riding a light beam, Kekule formulates the structure of benzene in a dream, and Fleming’s eye travels past the annoying mold on his glassware to the clear ring surrounding it — a lucid halo in a dish otherwise opaque with bacteria — and penicillin is born. Who knows how many scientific revolutions have been missed because their potential inaugurators disregarded the whimsical, the incidental, the inconvenient inside the laboratory?

The bourgeois period of history has to create the material basis of the new world — on the one hand universal intercourse founded upon the mutual dependency of mankind, and the means of that intercourse; on the other hand the development of the productive powers of man and the transformation of material production into a scientific domination of natural agencies. Bourgeois industry and commerce create these material conditions of a new world in the same way as geological revolutions have created the surface of the earth. When a great social revolution shall have mastered the results of the bourgeois epoch, the market of the world and the modern powers of production, and subjected them to the common control of the most advanced peoples, then only will human progress cease to resemble that hideous, pagan idol, who would not drink the nectar but from the skulls of the slain.

Simpson, the student of divinity, it was who arranged his conclusions probably with the best, though not most scientific, appearance of order. Out there, in the heart of unreclaimed wilderness, they had surely witnessed something crudely and essentially primitive. Something that had survived somehow the advance of humanity had emerged terrifically, betraying a scale of life monstrous and immature. He envisaged it rather as a glimpse into prehistoric ages, when superstitions, gigantic and uncouth, still oppressed the hearts of men: when the forces of nature were still untamed, the Powers that may have haunted a primeval universe not yet withdrawn. To this day he thinks of what he termed years later in a sermon 'savage and formidable Potencies lurking behind the souls of men, not evil perhaps in themselves, yet instinctively hostile to humanity as it exists.' ("The Wendigo")

The first objection to Darwinism is that it is only a guess and was never anything more. It is called a 'hypothesis,' but the word 'hypothesis,' though euphonious, dignified and high-sounding, is merely a scientific synonym for the old-fashioned word 'guess.' If Darwin had advanced his views as a guess they would not have survived for a year, but they have floated for half a century, buoyed up by the inflated word 'hypothesis.' When it is understood that “hypothesis” means 'guess,' people will inspect it more carefully before accepting it.

the scientific advances made by early Middle Eastern cultures, one of them being our modern numbering system, whose advantages over Roman numerals included ‘positional notation’ and the invention of the number zero. Of course, Langdon always ended this lecture with a reminder that Arab culture had also given mankind the word al-kuhl—the favorite beverage of Harvard freshmen—known as alcohol.

Adams and Jefferson lived in an age of quantification. It began with the measurement of time. Time used to be a wheel that turned, and turned again; during the scientific revolution, time became a line. Time, the easiest quantity to measure, became the engine of every empirical inquiry: an axis, an arrow. This new use and understanding of time contributed to the idea of progress—if time is a line instead of a circle, things can get better and even better, instead of forever rising and falling in endless cycles, like the seasons. The idea of progress animated American independence and animated, too, the advance of capitalism. The quantification of time led to the quantification of everything else: the counting of people, the measurement of their labor, and the calculation of profit as a function of time.

CARLOS: Thanks. But it’s pretty simple. We just follow the scientific method. No matter how advanced the scientific field gets, the foundation of scientific discovery is the scientific method we all learned in elementary school.  CECIL: I’m not sure I ever learned that.  CARLOS: Oh, it’s easy. Here, I’ll tell you and your listeners right now. The scientific method is four steps:  1. Find an object you want to know more about.  2. Hook that object up to a machine using wires or tubes.  3. Write things on a clipboard.  4. Read the results that the machine prints.  CECIL: Of course. I totally remember this now.

The very word "secrecy" is repugnant in a free and open society; and we are as a people inherently and historically opposed to secret societies, to secret oaths and to secret proceedings...Our way of life is under attack. Those who make themselves our enemy are advancing around the globe...no war ever posed a greater threat to our security. If you are awaiting a finding of "clear and present danger," then I can only say that the danger has never been more clear and its presence has never been more imminent...For we are opposed around the world by a monolithic and ruthless conspiracy that relies primarily on covert means for expanding its sphere of influence–on infiltration instead of invasion, on subversion instead of elections, on intimidation instead of free choice, on guerrillas by night instead of armies by day. It is a system which has conscripted vast human and material resources into the building of a tightly knit, highly efficient machine that combines military, diplomatic, intelligence, economic, scientific and political operations. Its preparations are concealed, not published. Its mistakes are buried, not headlined. Its dissenters are silenced, not praised. No expenditure is questioned, no rumor is printed, no secret is revealed.

To return to the general analysis of the Rosicrucian outlook. Magic was a dominating factor, working as a mathematics-mechanics in the lower world, as celestial mathematics in the celestial world, and as angelic conjuration in the supercelestial world. One cannot leave out the angels in this world view, however much it may have been advancing towards the scientific revolution. The religious outlook is bound up with the idea that penetration has been made into higher angelic spheres in which all religions were seen as one; and it is the angels who are believed to illuminate man's intellectual activities. In the earlier Renaissance, the magi had been careful to use only the forms of magic operating in the elemental or celestial spheres, using talismans and various rituals to draw down favourable influences from the stars. The magic of a bold operator like Dee, aims beyond the stars, aims at doing the supercelestial mathematical magic, the angel-conjuring magic. Dee firmly believed that he had gained contact with good angels from whom he learned advancement in knowledge. This sense of close contact with angels or spiritual beings is the hallmark of the Rosicrucian. It is this which infuses his technology, however practical and successful and entirely rational in its new understanding of mathematical techniques, with an unearthly air, and makes him suspect as possibly in contact, not with angels, but with devils.

There were other thinkers, Bowman also found, who held even more exotic views. They did not believe that really advanced beings would possess organic bodies at all. Sooner or later, as their scientific knowledge progressed, they would get rid of the fragile, disease-and-accident-prone homes that Nature had given them, and which doomed them to inevitable death. They would replace their natural bodies as they wore out—or perhaps even before that—by constructions of metal and plastic, and would thus achieve immortality. The brain might linger for a little while as the last remnant of the organic body, directing its mechanical limbs and observing the universe through its electronic senses—senses far finer and subtler than those that blind evolution could ever develop. Even

While a good story must give me a role, and must extend beyond my horizons, it need not be true. A story can be pure fiction, and yet provide me with an identity and make me feel that my life has meaning. Indeed, to the best of our scientific understanding, none of the thousands of stories that different cultures, religions and tribes have invented throughout history is true. They are all just human inventions. If you ask for the true meaning of life and get a story in reply, know that this is the wrong answer. The exact details don’t really matter. Any story is wrong, simply for being a story. The universe just does not work like a story. So why do people believe in these fictions? One reason is that their personal identity is built on the story. People are taught to believe in the story from early childhood. They hear it from their parents, their teachers, their neighbours and the general culture long before they develop the intellectual and emotional independence necessary to question and verify such stories. By the time their intellect matures, they are so heavily invested in the story, that they are far more likely to use their intellect to rationalise the story than to doubt it. Most people who go on identity quests are like children going treasure hunting. They find only what their parents have hidden for them in advance. Second, not only our personal identities but also our collective institutions are built on the story. Consequently, it is extremely frightening to doubt the story. In many societies, anyone who tries to do so is ostracised or persecuted. Even if not, it takes strong nerves to question the very fabric of society. For if indeed the story is false, then the entire world as we know it makes no sense. State laws, social norms, economic institutions – they might all collapse.

Just as there are those who accept every UFO report at face value, there are also those who dismiss the idea of alien visitation out of hand and with great passion. It is, they say, unnecessary to examine the evidence, and “unscientific” even to contemplate the issue. I once helped to organize a public debate at the annual meeting of the American Association for the Advancement of Science between proponent and opponent scientists of the proposition that some UFOs were spaceships; whereupon a distinguished physicist, whose judgment in many other matters I respected, threatened to sic the Vice President of the United States on me if I persisted in this madness. (Nevertheless, the debate was held and published, the issues were a little better clarified, and I did not hear from Spiro T. Agnew.)

Development means a capacity for self-sustaining growth. It means that an economy must register advances which in turn will promote further progress. The loss of industry and skill in Africa was extremely small, if we measure it from the viewpoint of modern scientific achievements or even by the standards of England in the late eighteenth century. However, it must be borne in mind that to be held back at one stage means that it is impossible to go on to a further stage. When a person is forced to leave school after only two years of primary school education, it is no reflection on him that he is academically and intellectually less developed than someone who had the opportunity to be schooled right through to university level. What Africa experienced in the early centuries of trade was precisely a loss of development opportunity, and this is of greatest importance.

And Mallow laughed joyously. "You've missed, Sutt, missed as badly as the Commdor himself. You've missed everything, and understood nothing. The Empire has always been a realm of colossal resources. They've calculated everything in planets, in stellar systems, in whole sectors of the Galaxy. Their generators are gigantic because they thought in gigantic fashion. "But we,—we, our little Foundation, our single world almost without metallic resources,—have had to work with brute economy. Our generators have had to be the size of our thumb, because it was all the metal we could afford. We had to develop new techniques and new methods,—techniques and methods the Empire can't follow because they have degenerated past the stage where they can make any vital scientific advance. "With all their nuclear shields, large enough to protect a ship, a city, an entire world; hey could never build one to protect a single man. To supply light and heat to a city, they have motors six stories high,—I saw them—where ours could fit into this room. And when I told one of their nuclear specialists that a lead container the size of a walnut contained a nuclear generator, he almost choked with indignation on the spot. "Why, they don't even understand their own colossi any longer. The machines work from generation to generation automatically and the caretakers are a hereditary caste who would be helpless if a single D-tube in all that vast structure burnt out. "The whole war is a battle between these two systems; between the Empire and the Foundation; between the big and the little. To seize control of a world, they bribe with immense ships that can make war, but lack all economic significance. We, on the other hand, bribe with little things, useless in war, but vital to prosperity and profits. "A king, or a Commdor, will take the ships and even make war. Arbitrary rulers throughout history have bartered their subjects' welfare for what they consider honor, and glory, and conquest. But it's still the little things in life that count—and Asper Argo won't stand up against the economic depression that will sweep all Korell in two or three years.

BOOK I 1     [184a] When the objects of an inquiry, in any department, have principles, (10) conditions, or elements, it is through acquaintance with these that knowledge, that is to say scientific knowledge, is attained. For we do not think that we know a thing until we are acquainted with its primary conditions or first principles, and have carried our analysis as far as its simplest elements. Plainly therefore in the science of Nature, (15) as in other branches of study, our first task will be to try to determine what relates to its principles. The natural way of doing this is to start from the things which are more knowable and obvious to us and proceed towards those which are clearer and more knowable by nature; for the same things are not ‘knowable relatively to us’ and ‘knowable’ without qualification. So in the present inquiry we must follow this method and advance from what is more obscure by nature, (20) but clearer to us, towards what is more clear and more knowable by nature. Now what is to us plain and obvious at first is rather confused masses, the elements and principles of which become known to us later by analysis. Thus we must advance from generalities to particulars; for it is a whole that is best known to sense-perception, (25) and a generality is a kind of whole, comprehending many things within it, like parts. [184b] Much the same thing happens in the relation of the name to the formula. (10) A name, e. g. ‘round’, means vaguely a sort of whole: its definition analyses this into its particular senses. Similarly a child begins by calling all men ‘father’, and all women ‘mother’, but later on distinguishes each of them.

A society that values order above all else will seek to suppress curiosity. But a society that believes in progress, innovation and creativity will cultivate it, recognising that the enquiring minds of its people constitute its most valuable asset. In medieval Europe, the enquiring mind – especially if it enquired too closely into the edicts of Church or state – was stigmatised. During the Renaissance and Reformation, received wisdoms began to be interrogated, and by the time of the Enlightenment, European societies started to see that their future lay with the curious, and encouraged probing questions rather than stamping on them. The result was the biggest explosion of new ideas and scientific advances in history. The great unlocking of curiosity translated into a cascade of prosperity for the nations that precipitated it. Today, we cannot know for sure if we are in the middle of this golden period or at the end of it. But we are, at the very least, in a lull. With the important exception of the internet, the innovations that catapulted Western societies ahead of the global pack are thin on the ground, while the rapid growth of Asian and South American economies has not yet been accompanied by a comparable run of indigenous innovation. Tyler Cowen, a professor of economics at George Mason University in Virginia, has termed the current period ‘the great stagnation’.

Yet, if we insist on dividing the world into multiple worlds, and if we consider all the wars, crimes, plundering, and exploitation the so-called ‘first world’ has committed against the worlds ranked lower, then does that really make it ‘first’ in anything? Is a world that commits all these atrocities worthy of being called ‘first’? If we, for the sake of argument, assume that the ‘first’ world is called so because it is more technologically and scientifically advanced, then we must raise another critical question, should humans be measured by their advances in technology, nuclear power, and other destructive weapons, or should they be measured by their level of humanity, mercy, and kindness?

Maybe somewhere telepaths walked the Earth, but I wasn't one of them. In the process, I began to realize that the wondrous exploits of telepaths were probably impossible--at least without outside assistance. But in the years that followed, I also slowly learned another lesson: to fathom the greatest secrets in the universe, one did not need telepathic or superhuman abilities. One just had to have an open, determined, and curious mind. In particular, in order to understand whether the fantastic devices of science fiction are possible, you have to immerse yourself in advanced physics. To understand the precise point when the possible becomes the impossible, you have to appreciate and understand the laws of physics.

Honesty requires that we each recognize the need to limit procreation, consumption, and waste, but equally we must radically reduce our expectations that machines will do our work for us or that therapists can make us learned or healthy. The only solution to the environmental crisis is the shared insight of people that they would be happier if they could work together and care for each other. Such an inversion of the current world view requires intellectual courage for it exposes us to the unenlightened yet painful criticism of being not only anti-people and against economic progress, but equally against liberal education and scientific and technological advance. We must face the fact that the imbalance between man and the environment is just one of several mutually reinforcing stresses, each distorting the balance of life in a different dimension. In this view, overpopulation is the result of a distortion in the balance of learning, dependence on affluence is the result of a radical monopoly of institutional over personal values, and faulty technology is inexorably consequent upon a transformation of means into ends

A disdain for the practical swept the ancient world. Plato urged astronomers to think about the heavens, but not to waste their time observing them. Aristotle believed that: “The lower sort are by nature slaves, and it is better for them as for all inferiors that they should be under the rule of a master.… The slave shares in his master’s life; the artisan is less closely connected with him, and only attains excellence in proportion as he becomes a slave. The meaner sort of mechanic has a special and separate slavery.” Plutarch wrote: “It does not of necessity follow that, if the work delight you with its grace, the one who wrought it is worthy of esteem.” Xenophon’s opinion was: “What are called the mechanical arts carry a social stigma and are rightly dishonoured in our cities.” As a result of such attitudes, the brilliant and promising Ionian experimental method was largely abandoned for two thousand years. Without experiment, there is no way to choose among contending hypotheses, no way for science to advance. The anti-empirical taint of the Pythagoreans survives to this day. But why? Where did this distaste for experiment come from? An explanation for the decline of ancient science has been put forward by the historian of science, Benjamin Farrington: The mercantile tradition, which led to Ionian science, also led to a slave economy. The owning of slaves was the road to wealth and power. Polycrates’ fortifications were built by slaves. Athens in the time of Pericles, Plato and Aristotle had a vast slave population. All the brave Athenian talk about democracy applied only to a privileged few. What slaves characteristically perform is manual labor. But scientific experimentation is manual labor, from which the slaveholders are preferentially distanced; while it is only the slaveholders—politely called “gentle-men” in some societies—who have the leisure to do science. Accordingly, almost no one did science. The Ionians were perfectly able to make machines of some elegance. But the availability of slaves undermined the economic motive for the development of technology. Thus the mercantile tradition contributed to the great Ionian awakening around 600 B.C., and, through slavery, may have been the cause of its decline some two centuries later. There are great ironies here.

Although Galileo was a devout Catholic, it was his conflict with the Vatican, sadly mismanaged on both sides, that lay at the basis of the running battle between science and religion, a tragic and confusing schism which persists unresolved. More than ever today, religion finds its revelatory truths threatened by scientific theory, and retreats into a defensive corner, while scientists go into the attack insisting that rational argument is the only valid criterion for an understanding of the workings of the universe. Maybe both sides have misunderstood the nature of their respective roles. Scientists are equipped to answer the mechanical question of how the universe and everything in it, including life, came about. But since their modes of thought are dictated by purely rational, materialistic criteria, physicists cannot claim to answer the questions of why the universe exists, and why we human beings are here to observe it, any more than molecular biologists can satisfactorily explain why – if our actions are determined by the workings of a selfish genetic coding – we occasionally listen to the voice of conscience and behave with altruism, compassion and generosity. Even these human qualities have come under attack from evolutionary psychologists who have ascribed altruism to a crude genetic theory by which familial cooperation is said to favour the survival of the species. Likewise the spiritual sophistication of musical, artistic and poetic activity is regarded as just a highly advanced function of primitive origins.

The longevity genes I work on are called “sirtuins,” named after the yeast SIR2 gene, the first one to be discovered. There are seven sirtuins in mammals, SIRT1 to SIRT7, and they are made by almost every cell in the body. When I started my research, sirtuins were barely on the scientific radar. Now this family of genes is at the forefront of medical research and drug development. Descended from gene B in M. superstes, sirtuins are enzymes that remove acetyl tags from histones and other proteins and, by doing so, change the packaging of the DNA, turning genes off and on when needed. These critical epigenetic regulators sit at the very top of cellular control systems, controlling our reproduction and our DNA repair. After a few billion years of advancement since the days of yeast, they have evolved to control our health, our fitness, and our very survival. They have also evolved to require a molecule called nicotinamide adenine dinucleotide, or NAD. As we will see later, the loss of NAD as we age, and the resulting decline in sirtuin activity, is thought to be a primary reason our bodies develop diseases when we are old but not when we are young.

PREFACE Cosmology is the study of the universe as a whole, including its birth and perhaps its ultimate fate. Not surprisingly, it has undergone many transformations in its slow, painful evolution, an evolution often overshadowed by religious dogma and superstition. The first revolution in cosmology was ushered in by the introduction of the telescope in the 1600s. With the aid of the telescope, Galileo Galilei, building on the work of the great astronomers Nicolaus Copernicus and Johannes Kepler, was able to open up the splendor of the heavens for the first time to serious scientific investigation. The advancement of this first stage of cosmology culminated in the work of Isaac Newton, who finally laid down the fundamental laws governing the motion of the celestial bodies. Instead of magic and mysticism, the laws of heavenly bodies were now seen to be subject to forces that were computable and reproducible. A second revolution in cosmology was initiated by the introduction of the great telescopes of the twentieth century, such as the one at Mount Wilson with its huge 100-inch reflecting mirror. In the 1920s, astronomer Edwin Hubble used this giant telescope to overturn centuries of dogma, which stated that the universe was static and eternal, by demonstrating that the galaxies in the heavens are moving away

Eternal Rest. If I have the temerity to prefer my own definition of the spirit of Buḍḍha's doctrine, it is because I think that all the misconceptions of it have arisen from a failure to understand his idea of what is real and what is unreal, what worth longing and striving for and what not. From this misconception have come all the unfounded charges that Buḍḍhism is an "atheistical," that is to say, a grossly materialistic, a nihilistic, a negative, a vice-breeding religion. Buḍḍhism denies the existence of a personal God—true: therefore—well, therefore, and notwithstanding all this, its teaching is neither what may be called properly atheistical, nihilistic, negative, nor provocative of vice. I will try to make my meaning clear, and the advancement of modern scientific research helps in this direction. Science divides the universe for us into two elements—matter and force;

The capitalist-imperialist governments, even though they themselves are about to be plundered, will not fight with any conviction against Fascism as such. Our rulers, those of them who understand the issue, would probably prefer to hand over every square inch of the British Empire to Italy, Germany, and Japan than to see Socialism triumphant. It was easy to laugh at Fascism when we imagined that it was based on hysterical nationalism, because it seemed obvious that the Fascist states, each regarding itself as the chosen people and patriotic contra mundum, would clash with one another. But nothing of the kind is happening. Fascism is now an international movement, which means not only that the Fascist nations can combine for the purposes of loot, but that they are groping, perhaps only half consciously as yet, toward a world-system. For the vision of the totalitarian state there is being substituted the vision of the totalitarian world. As I pointed out earlier, the advance of machine-technique must lead ultimately to some form of collectivism, but that form need not necessarily be equalitarian; that is, it need not be Socialism. Pace the economists, it is quite possible to imagine a world-society, economically collectivist–that is, with the profit principle eliminated–but will all political, military, and educational power in the hands of a small caste of rulers and their bravos. That or something like it is the objective of Fascism. And that, of course, is the slave-state, or rather the slave-world; it would probably be a stable form of society, and the chances are, considering the enormous wealth of the world if scientifically exploited, that the slaves would be well-fed and contented.

So far from a political ideology being the quasi-divine parent of political activity, it turns out to be its earthly stepchild. Instead of an independently premeditated scheme of ends to be pursued, it is a system of ideas abstracted from the manner in which people have been accustomed to go about the business of attending to the arrangements of their societies. The pedigree of every political ideology shows it to be the creature, not of premeditation in advance of political activity, but of meditation upon a manner of politics. In short, political activity comes first and a political ideology follows after; and the understanding of politics we are investigating has the disadvantage of being, in the strict sense, preposterous. Let us consider the matter first in relation to scientific hypothesis, which I have taken to play a role in scientific activity in some respects similar to that of an ideology in politics. If a scientific hypothesis were a self-generated bright idea which owed nothing to scientific activity, then empiricism governed by hypothesis could be considered to compose a self-contained manner of activity; but this certainly is not its character. The truth is that only a man who is already a scientist can formulate a scientific hypothesis; that is, an hypothesis is not an independent invention capable of guiding scientific inquiry, but a dependent supposition which arises as an abstraction from within already existing scientific activity. Moreover, even when the specific hypothesis has in this manner been formulated, it is inoperative as a guide to research without constant reference to the traditions of scientific inquiry from which it was abstracted. The concrete situation does not appear until the specific hypothesis, which is the occasion of empiricism being set to work, is recognized as itself the creature of owing how to conduct a scientific inquiry. Or consider the example of cookery. It might be supposed that an ignorant man, some edible materials, and a cookery book compose together the necessities of a self-moved (or concrete) activity called cooking. But nothing is further from the truth. The cookery book is not an independently generated beginning from which cooking can spring; it is nothing more than an abstract of somebody's knowledge of how to cook: it is the stepchild, not the parent of the activity. The book, in its tum, may help to set a man on to dressing a dinner, but if it were his sole guide he could never, in fact, begin: the book speaks only to those who know already the kind of thing to expect from it and consequently bow to interpret it. Now, just as a cookery book presupposes somebody who knows how to cook, and its use presupposes somebody who already knows how to use it, and just as a scientific hypothesis springs from a knowledge of how to conduct a scientific investigation and separated from that knowledge is powerless to set empiricism profitably to work, so a political ideology must be understood, not as an independently premeditated beginning for political activity, but as knowledge (abstract and generalized) of a concrete manner of attending to the arrangements of a society. The catechism which sets out the purposes to be pursued merely abridges a concrete manner of behaviour in which those purposes are already hidden. It does not exist in advance of political activity, and by itself it is always an insufficient guide. Political enterprises, the ends to be pursued, the arrangements to be established (all the normal ingredients of a political ideology), cannot be premeditated in advance of a manner of attending to the arrangements of a society; what we do, and moreover what we want to do, is the creature of how we are accustomed to conduct our affairs. Indeed, it often reflects no more than a dis­covered ability to do something which is then translated into an authority to do it.

When I was growing up it was still acceptable—not to me but in social terms—to say that one was not interested in science and did not see the point in bothering with it. This is no longer the case. Let me be clear. I am not promoting the idea that all young people should grow up to be scientists. I do not see that as an ideal situation, as the world needs people with a wide variety of skills. But I am advocating that all young people should be familiar with and confident around scientific subjects, whatever they choose to do. They need to be scientifically literate, and inspired to engage with developments in science and technology in order to learn more. A world where only a tiny super-elite are capable of understanding advanced science and technology and its applications would be, to my mind, a dangerous and limited one. I seriously doubt whether long-range beneficial projects such as cleaning up the oceans or curing diseases in the developing world would be given priority. Worse, we could find that technology is used against us and that we might have no power to stop it. I don’t believe in boundaries, either for what we can do in our personal lives or for what life and intelligence can accomplish in our universe. We stand at a threshold of important discoveries in all areas of science. Without doubt, our world will change enormously in the next fifty years. We will find out what happened at the Big Bang. We will come to understand how life began on Earth. We may even discover whether life exists elsewhere in the universe. While the chances of communicating with an intelligent extra-terrestrial species may be slim, the importance of such a discovery means we must not give up trying. We will continue to explore our cosmic habitat, sending robots and humans into space. We cannot continue to look inwards at ourselves on a small and increasingly polluted and overcrowded planet. Through scientific endeavour and technological innovation, we must look outwards to the wider universe, while also striving to fix the problems on Earth. And I am optimistic that we will ultimately create viable habitats for the human race on other planets. We will transcend the Earth and learn to exist in space. This is not the end of the story, but just the beginning of what I hope will be billions of years of life flourishing in the cosmos. And one final point—we never really know where the next great scientific discovery will come from, nor who will make it. Opening up the thrill and wonder of scientific discovery, creating innovative and accessible ways to reach out to the widest young audience possible, greatly increases the chances of finding and inspiring the new Einstein. Wherever she might be. So remember to look up at the stars and not down at your feet. Try to make sense of what you see and wonder about what makes the universe exist. Be curious. And however difficult life may seem, there is always something you can do and succeed at. It matters that you don’t just give up. Unleash your imagination. Shape the future.