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Like a vast, random experiment targeting the environment with health doomed to be collateral damage, chemicals have been released into the air, soil, and water since nineteenth-century industrialism. While some may shrug that the aerial release of chemical nanoparticles and nano-sensors, microprocessors, and biologicals under the classified Project Cloverleaf is just more of the same, nanoparticles able to breach the blood-brain barrier make it uniquely diabolical, as does the global conspiracy of power to turn the entire planet into an electromagnetic grid and plug everyone into it. War has gone corporate and all of life reframed as a battlespace of disposable noncombatants (civilians) redefined as potential “terrorists.” The military is no longer a protector but partnered with giant transnational corporations and wealthy dynastic cartels like that of Big Pharma and Big Oil.
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Elana Freeland (Under an Ionized Sky: From Chemtrails to Space Fence Lockdown)
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Years ago, however, with the development of lipid nanoparticles (LNPs), molecules were found that could act as brain-penetrating packaging material; that is, they could cross the blood-brain barrier. Their original use was to deliver chemotherapeutic drugs to the brain for the treatment of brain tumors (see sidebar Brain Toxic Packaging).37 It was no secret that LNPs could also be used to deliver genetic material in the form of DNA or mRNA to the brain or brain cells to become biologically active.
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Michael Nehls (The Indoctrinated Brain: How to Successfully Fend Off the Global Attack on Your Mental Freedom)
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Researchers at Shanghai Jiao Tong University in China, Saga University in Japan, and the University of California, Davis, proposed creating an artificial inorganic leaf modeled on the real thing. They took a leaf of Anemone vitifolia, a plant native to China, and injected its veins with titanium dioxide-a well-known industrial photocatalyst. By taking on the precise branching shape and structure of the leaf's veins, the titanium dioxide produced much higher light-harvesting ability than if ti was used in a traditional configuration. The researchers found an astounding 800 percent increase in hydrogen production as well. The total performance was 300 percent more active than the world's best commercial photocatalysts. When they added platinum nanoparticles to the mix, it increased activity by a further 1,000 percent.
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Jay Harman (The Shark's Paintbrush: Biomimicry and How Nature is Inspiring Innovation)
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have also been able to show in studies. My theory that the actual target is the memory center of our brain is also supported by the fact that lipid nanoparticles are used as gene transfer vehicles, which can efficiently cross the blood-brain barrier. This is no more justified for vaccination against a virus that primarily infects the respiratory tract than it is for vaccination of children, for whom the virus poses no threat in the first place.
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Michael Nehls (The Indoctrinated Brain: How to Successfully Fend Off the Global Attack on Your Mental Freedom)
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Finally, he’d treated some of what he saw as the clearer prints with gold nanoparticles and attached cotinine antibodies; this could tell him if the individual who left the prints was a smoker.
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James Chandler (Misjudged (Sam Johnstone, #1))
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For example, two commonly used emulsifiers—carboxymethylcellulose and polysorbate 80—reduce microbial diversity, induce inflammation, and promote obesity and colitis in mice. Titanium dioxide (TiO) nanoparticles, found in more than nine hundred food products, worsen intestinal inflammation. Additives such as these were snuck into our diet through the “Generally Recognized As Safe” loophole. They were GRASed into our diet. Yes, GRAS needs to be used as a verb because that’s the only way to adequately describe the careless acceptance of chemicals into our food supply by our regulatory agencies.
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Will Bulsiewicz (Fiber Fueled: The Plant-Based Gut Health Program for Losing Weight, Restoring Your Health, andOptimizing Your Microbiome)
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All this counting and measuring of nanoparticles, each one thirty-billionths of a metre. She had been trying to measure how much of herself she had lost, had been waiting for the possibility of splendour, waiting to understand why she had given herself, so completely, away. She would not wait anymore. She
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Charlotte Wood (Nanoparticles: Allen & Unwin shorts)
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powerful chemotherapy agents enclosed in microscopic nanoparticles are injected intravenously. These circulate with the blood in every tissue and organ in the body, but the chemotherapy drugs are inactive because they are trapped inside the nanoparticles. After eliminating all of the tumor that can be seen on the MR, the surgeon then refocuses the ultrasound to the surrounding brain to activate the nanoparticles, which release their pharmacological payload in the precise area around the tumor where residual microscopic extensions of the tumor have infiltrated. This allows very high concentrations of the drugs to be delivered focally to the brain while minimizing systemic side effects. The remainder of the chemo-laden nanoparticles will be excreted.
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John Grisham (The Tumor)
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With nanoparticles, it is possible to amplify the flavors and bring the material’s unique characteristics from colors to resistances.
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Edilson Gomes de Lima
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As they broke apart, the information safely handed over, the memory of the kiss left Dust full of an aching emptiness, everywhere his airborne nanoparticls drifted and spread.
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Elizabeth Bear (Dust (Jacob's Ladder, #1))
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Medical certificates verifying an individual as being virus-free are rapidly becoming obsolete paper money. Although a simple hologram embedded in a Medical Certificate would suffice to ensure its authenticity, Digital Identification (Blockchain) used with a mark or specific pattern of radiated “nanoparticles” (Quantum Dots) which can be scanned,is yet again the preferred method of authentication. This “Mark of the Beast” system for travel is made up of a random pattern of illuminated “Quantum Dots,” which use the ‘Digital Asset Modeling Language’ or DAML to identify the profile and health of the traveler.
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Jeremy Stone (Surviving the New World Order (Surviving The New World Order Trilogy Book 1))
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哪里能办乌克兰护照,【telegram:十852 55367074】(whatsApp:+852 55367074)『办理高仿护照 真护照,可根据客户样本制版印刷』可加急,哪里能办乌克兰护照,哪里能办乌克兰护照【telegram:+852 55367074】【WHATSApp:+852 55367074】『办理护照、签证、驾驶证、身份证ID、居留证、各种证明,发货速度快。』联系我们【飞机whatsapp 同号:+852 55367074】撰文丨王聪 编辑丨王多鱼 排版丨水成文 脂质纳米颗粒(LNP)递送系统的发明和发展是 mRNA 疫苗广泛应用过程中的里程碑。然而,越来越多的研究表明,传统的 PEG-LNP 配方的 mRNA 疫苗,已显示出某些不足之处。一个主要的担忧在于,mRNA 癌症疫苗需要高剂量和多次接种才能实现有效的肿瘤抑制。但 mRNA-LNP 平台具有很强的免疫原性,反复注射会激活炎症通路,导致促炎细胞因子分泌,并可能引发过敏性休克和细胞因子释放综合征等不良反应。此外,大量研究显示,PEG-LNP 被感染所摄取的情况不容忽视,可能导致肝毒性。 因此,有必要进一步改进和优化 LNP 递送系统,以提高 mRNA-LNP 疫苗的效果并确保生物安全性。 2025 年 8 月 4 日,清华大学化学系喻国灿助理教授、深圳湾实验室/国立新加坡大学陈小元教授、清华大学基础医学院/深圳湾实验室程功教授等在 Nature 子刊 Nature Materials 上发表了题为:Albumin-recruiting lipid nanoparticle potentiates the safety and efficacy of mRNA vaccines by avoiding liver accumulation 的研究论文。 该研究开发了一种白蛋白募集型脂质纳米颗粒,通过避免在肝脏中的蓄积,增强了 mRNA 疫苗的安全性和有效性。mRNA 疫苗的诞生和应用,是癌症治疗和传染病预防领域取得的重大突破。然而,传统的脂质纳米颗粒(LNP)递送的 mRNA 疫苗在肌肉注射后会在肝脏中积聚,这会带来肝毒性的风险,并降低疫苗效力。 在这项最新研究中,研究团队开发了一种白蛋白募集型脂质纳米颗粒系统,其具有高淋巴引流特性且不会在肝脏组织中蓄积,从而增强 mRNA 疫苗的效力和安全性。 研究团队构建了一个具有白蛋白结合能力的可电离脂质库,作为传统聚乙二醇偶联脂质的替代品。研究团队确定了一种经伊文思蓝修饰的脂质纳米颗粒(EB-LNP)配方,其体内表达水平高,借助白蛋白通过肌肉内淋巴管向淋巴结转运,被树突状细胞(DC)高度内化,且对肌肉内血管的渗透性低,从而避免了在肝脏组织中的蓄积,从递送路径上解决了传统 LNP 制剂的肝毒性问题。研究团队进一步开发了 EB-LNP 递送的 mRNA
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Li
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定做假斯洛伐克身份证ID,【telegram:十852 55367074】(whatsApp:+852 55367074)『办理高仿护照 真护照,可根据客户样本制版印刷』可加急,定做假斯洛伐克身份证ID,定做假斯洛伐克身份证ID【telegram:+852 55367074】【WHATSApp:+852 55367074】『办理护照、签证、驾驶证、身份证ID、居留证、各种证明,发货速度快。』联系我们【飞机whatsapp 同号:+852 55367074】撰文丨王聪 编辑丨王多鱼 排版丨水成文 脂质纳米颗粒(LNP)递送系统的发明和发展是 mRNA 疫苗广泛应用过程中的里程碑。然而,越来越多的研究表明,传统的 PEG-LNP 配方的 mRNA 疫苗,已显示出某些不足之处。一个主要的担忧在于,mRNA 癌症疫苗需要高剂量和多次接种才能实现有效的肿瘤抑制。但 mRNA-LNP 平台具有很强的免疫原性,反复注射会激活炎症通路,导致促炎细胞因子分泌,并可能引发过敏性休克和细胞因子释放综合征等不良反应。此外,大量研究显示,PEG-LNP 被感染所摄取的情况不容忽视,可能导致肝毒性。 因此,有必要进一步改进和优化 LNP 递送系统,以提高 mRNA-LNP 疫苗的效果并确保生物安全性。 2025 年 8 月 4 日,清华大学化学系喻国灿助理教授、深圳湾实验室/国立新加坡大学陈小元教授、清华大学基础医学院/深圳湾实验室程功教授等在 Nature 子刊 Nature Materials 上发表了题为:Albumin-recruiting lipid nanoparticle potentiates the safety and efficacy of mRNA vaccines by avoiding liver accumulation 的研究论文。 该研究开发了一种白蛋白募集型脂质纳米颗粒,通过避免在肝脏中的蓄积,增强了 mRNA 疫苗的安全性和有效性。mRNA 疫苗的诞生和应用,是癌症治疗和传染病预防领域取得的重大突破。然而,传统的脂质纳米颗粒(LNP)递送的 mRNA 疫苗在肌肉注射后会在肝脏中积聚,这会带来肝毒性的风险,并降低疫苗效力。 在这项最新研究中,研究团队开发了一种白蛋白募集型脂质纳米颗粒系统,其具有高淋巴引流特性且不会在肝脏组织中蓄积,从而增强 mRNA 疫苗的效力和安全性。 研究团队构建了一个具有白蛋白结合能力的可电离脂质库,作为传统聚乙二醇偶联脂质的替代品。研究团队确定了一种经伊文思蓝修饰的脂质纳米颗粒(EB-LNP)配方,其体内表达水平高,借助白蛋白通过肌肉内淋巴管向淋巴结转运,被树突状细胞(DC)高度内化,且对肌肉内血管的渗透性低,从而避免了在肝脏组织中的蓄积,从递送路径上解决了传统 LNP 制剂的肝毒性问题。研究团队进一步开发了 EB-LNP
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Li