Mcinnes Quotes

There are two kinds of people that wear bike helmets: kids and retards.

It’s hard not to let negative emotions take over and leave their mark, but it seems that our lives depend on it; the reality is that stress kills. When it goes unresolved, stress can lead to chronic disease, causing premature death. The elevation of the stress hormone cortisol lowers immune system functioning, increases blood pressure, and cholesterol, and increases the risk of heart disease, cancer, and various other diseases. However, grief doesn’t last forever, despite how devastating and all-encompassing it can be. With the right help, support, and outlook, recovery will bring the body and mind to a new place of healing. We will never be the same again, but we will be stronger versions of ourselves. It’s important to remember to approach recovery with some level of gratitude for the beauty of life—it’s important to always express, accept, and learn from ourselves.

Tragically, there are none so prejudiced as those who are infected with the curse of "knowingness.” A 1% solution of strychnine qualifies as mostly water, but has quite a different effect on the human system. The human organism is itself mostly a bag of water, but a bag of water could not build the pyramids or launch a spacecraft to the moon and return it to earth.

The McInnes event at the Republican club was really a jumping-off point for the GOP into what would eventually become a full embrace of domestic extremist violence.

In one proposal three years ago Brett McInnes of the National University of Singapore drew on ideas from the leading candidate for a quantum theory of gravity—string theory.

But if she thinks women are the only ones dealing with this crap, she's pretty freaking clueless. What about the stuff guys are supposed to think and say and do to prove we're manly men, to prove we're in control and strong as iron and fearless? What about the way guys call each other faggot in the hallway if one of them accidentally gets too close to another, or the way I have no choice but to fight whenever some punk decides he wants a piece of me. Refusing to fight makes me look like a pantywaist, and then every other guy on the planet wants to hurt me, too. That's just how it is.

Healing was not straightforward and was much easier said than done. Losing loved ones is one of the most overwhelming experiences of being human—nothing compares to it. Nevertheless, life marches on whether we walk along with it, and whether we choose to die inside or move on is up to us.

After an indefinite amount of time, a police officer knocked on the door and came into the room. He introduced himself, then said, “I want to start by saying how very sorry I am for your loss.” He stood in silence for a moment. We thanked him for his condolences, then waited for him to proceed. He cleared his throat and began, “The woman who killed your son feels terrible about it.” We looked at him in shock. “She is beside herself and is practically inconsolable,” he added. The room became deathly quiet. We could not believe what we were hearing. Had we misheard him? We looked around at each other, perplexed. Was he trying to elicit sympathy for our son’s killer? Wait, What? It was one of those moments one can’t forget, a significant point that cannot be erased. Something didn’t feel right, and even though I didn’t understand it at the time, we later learned what the officer meant.

While the Proud Boys were stuck at a corner waiting for a WALK sign, a guy on a bicycle stopped and shouted, “Fuck Trump!” “What’d you say?” Zach snapped. “Say that again, pussy!” Trembling with adrenaline, he glanced toward McInnes to see how his show of bravery was going over. But McInnes, who was busy chatting with Fairbanks, hadn’t noticed. The man threw his bicycle to the ground and started to approach, looking a bit bigger with every step. “Sure, I’ll say it again,” he said. “Fuck. Trump.” The light changed. Zach put his head down and kept walking.

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Determined to save their little company, Smith and Alvi threw themselves into the business of selling ads while McInnes stuck to editorial. “Those guys had a real struggle, trying to get people to buy ads and market the Vice brand,” McInnes recalled. “I was still writing the Vice ‘Guide to Eating Pussy’ and having a great time.

At the beginning of the twenty-first century, physicians such as Iain McInnes were finding out that new biologic drugs designed for inflammatory conditions like rheumatoid arthritis could treat symptoms of depression. A number of researchers have since trawled back through the results of clinical trials that tested anti-inflammatory drugs for various chronic inflammatory conditions such as rheumatoid arthritis, lupus, psoriasis, asthma and inflammatory bowel disease. They were particularly interested in trials that also reported data for symptoms of depression as a secondary outcome. The overwhelming picture is that anti-inflammatory drugs – from older, generalized drugs such as ibuprofen and aspirin to new, targeted monoclonal antibodies – tend to improve depressive symptoms.22 One study, carried out in 2020, was able to look at very detailed patient data from eighteen clinical trials and factored in patients’ physical improvements. These trials had used a range of new anti-inflammatory drugs designed to target the inflammation behind various autoimmune diseases. Two drugs in particular demonstrated an improvement in low mood, regardless of improvement in physical symptoms. These were both antibody drugs that specifically targeted pro-inflammatory cytokines: sirukumab relieves rheumatoid arthritis by targeting IL-6, and ustekinumab treats psoriasis by blocking the cytokines for IL-12 and IL-23. Here we have data to back up Iain McInnes’s observations in his arthritis clinic: anti-inflammatory medication treating the psychological symptoms of depression, regardless of the state of physical symptoms. This doesn’t just help to strengthen an argument for inflammation causing some forms of depression; it offers hope of a treatment.

As with any new drug, McInnes was on the lookout for side effects. One common one that he noted was remarkable: ‘Some of my patients reported a significant improvement in their mood, describing themselves as feeling as good as they had done for years. But when I examined their hands, their fingers were just as swollen as before; their knuckles just as deformed.’ In some patients, these new anti-inflammatory drugs seemed to lift mood and relieve depression, even if they did not deliver their intended outcome for ‘physical’ symptoms.