History Of Genetics Quotes

Not one of your pertinent ancestors was squashed, devoured, drowned, starved, stranded, stuck fast, untimely wounded, or otherwise deflected from its life's quest of delivering a tiny charge of genetic material to the right partner at the right moment in order to perpetuate the only possible sequence of hereditary combinations that could result -- eventually, astoundingly, and all too briefly -- in you.

Consider the fact that for 3.8 billion years, a period of time older than the Earth's mountains and rivers and oceans, every one of your forebears on both sides has been attractive enough to find a mate, healthy enough to reproduce, and sufficiently blessed by fate and circumstances to live long enough to do so. Not one of your pertinent ancestors was squashed, devoured, drowned, starved, stranded, stuck fast, untimely wounded, or otherwise deflected from its life's quest of delivering a tiny charge of genetic material to the right partner at the right moment in order to perpetuate the only possible sequence of hereditary combinations that could result -- eventually, astoundingly, and all too briefly -- in you.

When you have only ever experienced privilege, equality feels like oppression.

If we define "beauty" as having blue eyes (and only blue eyes), then we will, indeed, find a "gene for beauty." If we define "intelligence" as the performance on only one kind of test, then we will, indeed, find a "gene for intelligence." The genome is only a mirror for the breadth or narrowness of human imagination.

People with family histories of alcoholism tend to have lower levels of endorphins- the endogenous morphine that is responsible for many of our pleasure responses- than do people genetically disinclined to alcoholism. Alcohol will slightly raise the endorphin level of people without the genetic basis for alcoholism; it will dramatically raise the endorphin level of people with that genetic basis. Specialists spend a lot of time formulating exotic hypotheses to account for substance abuse. Most experts point out, strong motivations for avoiding drugs; but there are also strong motivations for taking them. People who claim not to understand why anyone would get addicted to drugs are usually people who haven't tried them or who are genetically fairly invulnerable to them.

Cancer, perhaps, is an ultimate perversion of genetics—a genome that becomes pathologically obsessed with replicating itself. The

History does show that boys who dance are far more likely to pass along their genes than boys who don't. Boys who dance are genetic volcanoes.

A mycelial network is a map of a fungus’s recent history and is a helpful reminder that all life-forms are in fact processes not things. The “you” of five years ago was made from different stuff than the “you” of today. Nature is an event that never stops. As William Bateson, who coined the word genetics, observed, “We commonly think of animals and plants as matter, but they are really systems through which matter is continually passing.

According to the science of biology, people were not ‘created’. They have evolved. And they certainly did not evolve to be ‘equal’. The idea of equality is inextricably intertwined with the idea of creation. The Americans got the idea of equality from Christianity, which argues that every person has a divinely created soul, and that all souls are equal before God. However, if we do not believe in the Christian myths about God, creation and souls, what does it mean that all people are ‘equal’? Evolution is based on difference, not on equality. Every person carries a somewhat different genetic code, and is exposed from birth to different environmental influences. This leads to the development of different qualities that carry with them different chances of survival. ‘Created equal’ should therefore be translated into ‘evolved differently’.

Still, if history and science have taught us anything, it is that passion and desire are not the same as truth. The human mind evolved to believe in the gods. It did not evolve to believe in biology. Acceptance of the supernatural conveyed a great advantage throughout prehistory when the brain was evolving. Thus it is in sharp contrast to biology, which was developed as a product of the modern age and is not underwritten by genetic algorithms. The uncomfortable truth is that the two beliefs are not factually compatible. As a result those who hunger for both intellectual and religious truth will never acquire both in full measure.

With the capacity to represent the world in signs and symbols comes the capacity to change it, which, as it happens, is also the capacity to destroy it. A tiny set of genetic variations divides us from the Neanderthals, but that has made all the difference.

Do you think we enjoy hearing about your brand-new million-dollar home when we can barely afford to eat Kraft Dinner sandwiches in our own grimy little shoe boxes and we're pushing thirty? A home you won in a genetic lottery, I might add, sheerly by dint of your having been born at the right time in history? You'd last about ten minutes if you were my age these days.

War has changed. It's no longer about nations, ideologies, or ethnicity. It's an endless series of proxy battles, fought by mercenaries and machines. War--and it's consumption of life--has become a well-oiled machine. War has changed. ID-tagged soldiers carry ID-tagged weapons, use ID-tagged gear. Nanomachines inside their bodies enhance and regulate their abilities. Genetic control, information control, emotion control, battlefield control…everything is monitored and kept under control. War…has changed. The age of deterrence has become the age of control, all in the name of averting catastrophe from weapons of mass destruction, and he who controls the battlefield, controls history. War…has changed. When the battlefield is under total control, war becomes routine.

Illness might progressively vanish so might identity. Grief might be diminished, but so might tenderness. Traumas might be erased but so might history. Infirmities might disappear, but so might vulnerability. Chance would become mitigated, but so, inevitably, would choice.

Thoughtful white people know they are inferior to black people. Anyone who has studied the genetic phase of biology knows that white is considered recessive and black is considered dominant. When you want strong coffee, you ask for black coffee. If you want it light, you want it weak, integrated with white milk. Just like these Negroes who weaken themselves and their race by this integrating and intermixing with whites. If you want bread with no nutritional value, you ask for white bread. All the good that was in it has been bleached out of it, and it will constipate you. If you want pure flour, you ask for dark flour, whole-wheat flour. If you want pure sugar, you want dark sugar.

I READ SOMEWHERE that human beings are genetically predisposed to record history. We believe it will prevent us from doing stupid things in the future.

Those Who From Heaven To Earth Came". They landed on Earth, colonized it, mining the Earth for gold and other minerals, establishing a spaceport in what today is the Iraq-Iran area, and lived in a kind of idealistic society as a small colony. They returned when Earth was more populated and genetically interfered in our indigenous DNA to create a slave-race to work their mines, farms, and other enterprises in Sumeria, which was the so-called Cradle of Civilization in out-dated pre-1980s school history texts. They created Man, Homo Sapiens, through genetic manipulation with themselves and ape man Homo Erectus.

Maybe the trick is not to define yourself as a container for your experiences, your thoughts. Maybe it's to assume you are larger than the things you have felt over a series of years, that your history is not a list of things your body has done or been present for, that your family is not people who you spent a lot of time around as a child or carry your genetic code. Maybe the trick is to push violently at your own boundaries, to find your own contradictions, and use your teeth and nails to destroy what separates you from something else. I am trying.

There is a strange emptiness to life without myths. I am African American — by which I mean, a descendant of slaves, rather than a descendant of immigrants who came here willingly and with lives more or less intact. My ancestors were the unwilling, unintact ones: children torn from parents, parents torn from elders, people torn from roots, stories torn from language. Past a certain point, my family’s history just… stops. As if there was nothing there. I could do what others have done, and attempt to reconstruct this lost past. I could research genealogy and genetics, search for the traces of myself in moldering old sale documents and scanned images on microfiche. I could also do what members of other cultures lacking myths have done: steal. A little BS about Atlantis here, some appropriation of other cultures’ intellectual property there, and bam! Instant historically-justified superiority. Worked great for the Nazis, new and old. Even today, white people in my neck of the woods call themselves “Caucasian”, most of them little realizing that the term and its history are as constructed as anything sold in the fantasy section of a bookstore. These are proven strategies, but I have no interest in them. They’ll tell me where I came from, but not what I really want to know: where I’m going. To figure that out, I make shit up.

Genetic tests,” as Eric Topol, the medical geneticist described it, “are also moral tests. When you decide to test for ‘future risk,’ you are also, inevitably, asking yourself, what kind of future am I willing to risk?” Three case studies illustrate the power and the peril of using genes to predict “future risk.

You only had to look at Noah and his wife, or at their three sons and their three wives, to realize what a genetically messy lot the human race would turn out to be.

Race is a social construct. This does not mean that it is invalid or unimportant.

Throughout history, great philosophical minds have grappled with the nature of identity. What makes a person a person? What combination of memory, history, imagination, experience, subjectivity, genetic substance, and that ineffable thing called the soul makes us who we are? Is who we are the same as who we believe ourselves to be?

Me and the folks who buy my food are like the Indians -- we just want to opt out. That's all the Indians ever wanted -- to keep their tepees, to give their kids herbs instead of patent medicines and leeches. They didn't care if there was a Washington, D.C., or a Custer or a USDA; just leave us alone. But the Western mind can't bear an opt-out option. We're going to have to refight the Battle of the Little Big Horn to preserve the right to opt out, or your grandchildren and mine will have no choice but to eat amalgamated, irradiated, genetically prostituted, barcoded, adulterated fecal spam from the centralized processing conglomerate.

You'd think family would be the one sure thing in life, the gimme? Points you got just for being born? So much thick, meaty stuff bound you to these people, so many interlocking spirals of history, genetics, common cause, and struggle that it should be the most basic of all drives, that you would strive to protect and love one another, yet this bond that should be the big no-brainer was in fact the hardest thing.

There were three things sought by invaders who crossed oceans to discover America. Those were gold, gospel, glory. There are four things sought by aliens who crossed heavens to discover planet earth. Those are gold, gospel, glory, gene.

It took the full force of human genetics to bring sanity to the study of madness.

make a choice to change the narrative, to overwrite the patterns of history. That a person does not have to be defined by the past. Or by genetics. People can change.

Unless you eat foods clearly marked “Certified organic by the USDA,” you are taking part in a genetic experiment that is unprecedented in earth’s long history.

The future is malleable, and to see it, you just have to listen to history and have a grand enough vision. - Salome Gluecksohn Waelsch - Developmental Genetics

I’ve always felt there’s something genetically instilled and inbred in Californians—that California is a place of death, a place people are drawn to because they don’t realize deep down they’re actually afraid of what they want. It’s new, and they’re escaping their histories while at the same time moving headlong toward their own extinctions. Desire and death are all mixed up with the thrill and the risk of the unknown. It’s a variation of what Freud called the “death instinct.

The calcium in your bones came from a star. We are all made from recycled bits and pieces of the universe. This matters because origins matter. For example, if you were born to a reigning monarch but kidnapped by the black market baby underground shortly after birth and sent to America where you were raised by common, unremarkable people from Ohio, and when you were in your thirties working as a humble UPS driver, dignitaries landed their helicopter on the roof of your crummy apartment building and informed you of their thirty-plus year search for you, His Royal Highness, the course of your life might change. You know? Our familial genetic origins -medical histories- inform us of medical conditions which exist in our families and when we know about these specific conditions, we can sometimes take certain actions to prevent them. Which is why I think it’s important to consider that billions of years before we were students and mothers and dog trainers and priests, we were particles that would form into star after star after star until forever passed, and instead of a star what formed was life; simplistic, crude, miraculous. And after another infinity, there we were. And this is why for you, anything is possible. Because you are made out of everything.

One has to put aside the popular notion that language and culture are endlessly passed on from generation to generation, rather as if ‘Scottishness’ or ‘Englishness’ were essential constituents of some national genetic code. If this were so, it would never be possible to forge new nations – like the United States of America or Australia – from diverse ethnic elements.

If there is one central intellectual reality at the end of the twentieth century, it is that the biological approach to psychiatry--treating mental illness as a genetically influenced disorder of brain chemistry--has been a smashing success. Freud's ideas, which dominated the history of psychiatry for the past half century, are now vanishing like the last snows of winter.

Genetics is messy and mathematical, but powerful if deployed in the right way. People are horny. Lives are complex. A secret history is truly hidden in the mosaics of our genomes, but caveat emptor. No

There was nothing special about humans. Nobody, least of all humans themselves, had any inkling that their descendants would one day walk on the moon, split the atom, fathom the genetic code and write history books.

Multiple allergies are perhaps the most obvious sign of immune system overreaction. Patients with CFIDS frequently have a past history of allergies, implying that their immune response is genetically primed for a vigorous response. Other patients with CFIDS develop allergic symptoms after the onset of their illness. CFIDS patients have a hair trigger for allergies.

They say things are determined by genetics, by parenting, by heredity, by climate, by diet, by geography, by time spent in the womb, by nature, by nurture. They fail to hear the elephant in the room, trumpeting away: history.

Look at them, the bugs. Humans have used everything in their power to extinguish them: every kind of poison, aerial sprays, introducing and cultivating their natural predators, searching for and destroying their eggs, using genetic modification to sterilize them, burning with fire, drowning with water. Every family has bug spray, every desk has a flyswatter under it… this long war has been going on for the entire history of human civilization. But the outcome is still in doubt. The bugs have not been eliminated. They still proudly live between the heavens and the earth, and their numbers have not diminished from the time before the appearance of the humans. The Trisolarans who deemed the humans bugs seemed to have forgotten one fact: The bugs have never been truly defeated. A small black cloud covered the sun and cast a moving shadow against the ground. This was not a common cloud, but a swarm of locusts that had just arrived. As the swarm landed in the fields nearby, the three men stood in the middle of a living shower, feeling the dignity of life on Earth. Ding Yi and Wang Miao poured the two bottles of wine they had with them on the ground beneath their feet, a toast for the bugs.

In our national parlance, what's usually meant by the word "maverick" is someone who skirts the edge of sanity--or is so insane as to appear sane--who then does something absolutely insane and yet, after the passage of time, and especially if the maverick's creation yields a profit of any kind, is deemed less and less insane until the maverick worms his or her way into the fibers of history. Then generations grow to envy the ingenuity and courage of the maverick while glossing over the maverick's genetic kookiness. On such shoulders, a country rises.

none of the ways in which we talk about race today stands up to the scrutiny that genetics has enabled. Families are too untidy, human history is too convoluted, people too motile. The deck has been shuffled and reshuffled. Genetics has shown that people are different, and these differences cluster according to geography and culture, but never in a way that aligns with the traditional concepts of human races.

Bailey had profoundly changed the conversation around sexual identity away from the 1960s rhetoric of “choice” and “personal preference” toward biology, genetics, and inheritance. If we did not think of variations in height or the development of dyslexia or type 1 diabetes as choices, then we could not think of sexual identity as a choice. But

Look at them, the bugs. Humans have used everything in their power to extinguish them: every kind of poison, aerial sprays, introducing and cultivating their natural predators, searching for and destroying their eggs, using genetic modification to sterilize them, burning with fire, drowning with water. Every family has bug spray, every desk has a fly-swatter under it... this long war has been going on for the entire history of human civilization. But the outcome is still in doubt. The bugs have not been eliminated.

We hold these truths to be self-evident, that all men are created equal, that they are endowed by their Creator with certain unalienable rights, that among these are life, liberty, and the pursuit of happiness. According to the science of biology, people were not ‘created’. They have evolved. And they certainly did not evolve to be ‘equal’. The idea of equality is inextricably intertwined with the idea of creation. The Americans got the idea of equality from Christianity, which argues that every person has a divinely created soul, and that all souls are equal before God. However, if we do not believe in the Christian myths about God, creation and souls, what does it mean that all people are ‘equal’? Evolution is based on difference, not on equality. Every person carries a somewhat different genetic code, and is exposed from birth to different environmental influences. This leads to the development of different qualities that carry with them different chances of survival. ‘Created equal’ should therefore be translated into ‘evolved differently’. Just as people were never created, neither, according to the science of biology, is there a ‘Creator’ who ‘endows’ them with anything. There is only a blind evolutionary process, devoid of any purpose, leading to the birth of individuals. ‘Endowed by their creator’ should be translated simply into ‘born’. Equally, there are no such things as rights in biology. There are only organs, abilities and characteristics. Birds fly not because they have a right to fly, but because they have wings. And it’s not true that these organs, abilities and characteristics are ‘unalienable’. Many of them undergo constant mutations, and may well be completely lost over time. The ostrich is a bird that lost its ability to fly. So ‘unalienable rights’ should be translated into ‘mutable characteristics’. And what are the characteristics that evolved in humans? ‘Life’, certainly. But ‘liberty’? There is no such thing in biology. Just like equality, rights and limited liability companies, liberty is something that people invented and that exists only in their imagination. From a biological viewpoint, it is meaningless to say that humans in democratic societies are free, whereas humans in dictatorships are unfree. And what about ‘happiness’? So far biological research has failed to come up with a clear definition of happiness or a way to measure it objectively. Most biological studies acknowledge only the existence of pleasure, which is more easily defined and measured. So ‘life, liberty, and the pursuit of happiness’ should be translated into ‘life and the pursuit of pleasure’. So here is that line from the American Declaration of Independence translated into biological terms: We hold these truths to be self-evident, that all men evolved differently, that they are born with certain mutable characteristics, and that among these are life and the pursuit of pleasure.

I think knowledge is a blessing, not a curse. This is especially true in the case of genetic knowledge. To understand the molecular nature of cancer for the first time, to diagnose and prevent Alzheimer’s disease, to discover the secrets of human history, to reconstruct the organisms that populated the pre-Cambrian seas – these seem to me to be immense blessings.

...most words for ghost are pieces of mica that carefully layered will make a window out of fire. It's cold and the faces at the window do what faces usually do they open onto a genetic history that looks up suddenly and it's the eyes everyone says you can't say that's not alive

We now even know that trauma can actually create genetic changes that can be passed down through generations. If you have a great-grandparent, grandparent, or parent with a serious trauma history, you are wired for a different response than someone who had family members without a lot of life drama.

Race is a by-product of racism. In fact, race doesn’t exist.” Damaras said this in the way a person might say water is wet. “Some of you look surprised.” She adjusted her feet and straightened her back. “It’s a social construct. There has never been any scientific or genetic evidence to back up the concept of race. Despite it being false, it has woven its way into the fabric of all of our societies.

Two revolutions coincided in the 1950s. Mathematicians, including Claude Shannon and Alan Turing, showed that all information could be encoded by binary digits, known as bits. This led to a digital revolution powered by circuits with on-off switches that processed information. Simultaneously, Watson and Crick discovered how instructions for building every cell in every form of life were encoded by the four-letter sequences of DNA. Thus was born an information age based on digital coding (0100110111001…) and genetic coding (ACTGGTAGATTACA…). The flow of history is accelerated when two rivers converge.

A recent landmark global study in population genetics by a team of internationally reputed scientists (as reported in The History and Geography of Human Genes, by Luca CavalliSforza, Paolo Menozzi and Alberta Piazzo, Princeton University Press) reveals that the people who inhabited the Indian subcontinent, including Europe, concludes that all belong to one single race of Caucasian type. This confirms once again that there really is no racial difference between north Indians and south Indian Dravidians.

I have had my mother's wing of my genetic ancestry analyzed by the National Geographic tracing service and there it all is: the arrow moving northward from the African savannah, skirting the Mediterranean by way of the Levant, and passing through Eastern and Central Europe before crossing to the British Isles. And all of this knowable by an analysis of the cells on the inside of my mouth. I almost prefer the more rambling and indirect and journalistic investigation, which seems somehow less… deterministic.

As human fictions are translated into genetic and electronic codes, the intersubjective reality will swallow up the objective reality and biology will merge with history. In the twenty-first century fiction might thereby become the most potent force on earth, surpassing even wayward asteroids and natural selection.

The maestro of the orchestra of life is the genetic material which directs the proteins, sugars and minerals. It receives signals about the external environment, decides the speed and timing of the reactions and communicates this information to all cells. It breaks down sugars, clears waste, repairs the membrane and reproduces.

if you were to identify a single person who embodies us Indians the best, who do you think it should be? Ideally, it should be a tribal woman because she is most likely to be carrying the deepest-rooted and widest-spread mtDNA lineage in India today, M2. In a genetic sense, she would represent all of our history, with very little left out. She shares the most with the largest number of Indians, no matter where in the social ladder they stand, what language they speak and which region they inhabit because we are all migrants, and we are all mixed.

One of the deep prejudices that the age of mechanism instilled in our culture, and that infects our religious and materialist fundamentalisms alike, is a version of the so-called genetic fallacy: to wit, the mistake of thinking that to have described a thing’s material history or physical origins is to have explained that thing exhaustively. We tend to presume that if one can discover the temporally prior physical causes of some object—the world, an organism, a behavior, a religion, a mental event, an experience, or anything else—one has thereby eliminated all other possible causal explanations of that object. But this is a principle that is true only if materialism is true, and materialism is true only if this principle is true, and logical circles should not set the rules for our thinking.

The fundamental core of contemporary Darwinism, the theory of DNA-based reproduction and evolution, is now beyond dispute among scientists. It demonstrates its power every day, contributing crucially to the explanation of planet-sized facts of geology and meteorology, through middle-sized facts of ecology and agronomy, down to the latest microscopic facts of genetic engineering. It unifies all of biology and the history of our planet into a single grand story. Like Gulliver tied down in Lilliput, it is unbudgeable, not because of some one or two huge chains of argument that might–hope against hope–have weak links in them, but because it is securely tied by hundreds of thousands of threads of evidence anchoring it to virtually every other field of knowledge. New discoveries may conceivably lead to dramatic, even 'revolutionary' shifts in the Darwinian theory, but the hope that it will be 'refuted' by some shattering breakthrough is about as reasonable as the hope that we will return to a geocentric vision and discard Copernicus.

But the western mind can't bear an opt- out option. we're going to have to re-fight the Battle of the Little Bighorn to preserve the right to opt-out, or your grandchildren and mine will have no choice but to eat amalgamated, irradiated, genetically prostituted, bar-coded, adulterated fecal spam from the centralized processing conglomerate." Joel Salatin

It's worth remembering that [having a baby] is not of vital use to you as a woman. Yes, you could learn thousands of interesting things about love, strength, faith, fear, human relationships, genetic loyalty, and the effect of apricots on an immune digestive system. But I don't think there's a single lesson that motherhood has to offer that couldn't be learned elsewhere. If you want to know what's in motherhood for you, as a woman, then-in truth-it's nothing you couldn't get from, say, reading the 100 greatest books in human history; learning a foreign language well enough to argue in it; climbing hills; loving recklessly; sitting quietly, alone, in the dawn; drinking whiskey with revolutionaries; learning to do close-hand magic; swimming in a river in the winter; growing foxgloves, peas, and roses; calling your mum; singing while you walk; being polite; and always, always helping strangers. No one has ever claimed for a minute that childless men have missed out on a vital aspect of their existence, and were the poorer and crippled by it. Da Vinci, Van Gogh, Newton, Faraday, Plato, Aquinas, Beethoven, Handel, Kant, Hume, Jesus. They all seem to have managed quite well.

Beauty is in the streets,” they say in Paris. We travelers know our favorites, Parisians know theirs. Jean Genet liked to stand with his friend Giacometti at the foot of rue Oberkampf, taking in its long uphill from the Marais to Belleville. Simone Weil loved walking the quays of Île Saint-Louis in her native river city. The scruffy streets of the ninth were François Truffaut’s muse and mother. As cities evolve and erupt, streets change; Parisians come and go. But the beauty remains.

The Church’s systematic murder, imprisonment, and denunciation of some of history’s most brilliant scientific minds delayed human progress by at least a century. Fortunately, today, with our better understanding of the benefits of science, the Church has tempered its attacks…” Edmond sighed. “Or has it?” A globe logo with a crucifix and serpent appeared with the text: Madrid Declaration on Science & Life “Right here in Spain, the World Federation of the Catholic Medical Associations recently declared war on genetic engineering, proclaiming that ‘science lacks soul’ and therefore should be restrained by the Church.

Old measures of health not only have failed to improve significantly but have stayed the same: some have even worsened. Mainstream newspapers and magazines often report disease in an ethnocentric manner that shrouds its true cost among African Americans. For example, despite the heavy emphasis on genetic ailments among blacks, fewer than 0.5 percent of black deaths—that’s less than one death in two hundred—can be attributed to hereditary disorders such as sickle-cell anemia. A closer look at the troubling numbers reveals that blacks are dying not of exotic, incurable, poorly understood illnesses nor of genetic diseases that target only them, but rather from common ailments that are more often prevented and treated among whites than among blacks.

The train passed through a series of tunnels. Because the overhead light fixtures had no bulbs in them, some people lit candles inside the tunnels, which dramatically illuminated their black, liquid eyes. There was a solemn, almost devotional cynicism to these eyes, reflecting, as though by a genetic process, all of the horrors witnessed by generation upon generation of forebears.

you have also been extremely – make that miraculously – fortunate in your personal ancestry. Consider the fact that for 3.8 billion years, a period of time older than the Earth’s mountains and rivers and oceans, every one of your forebears on both sides has been attractive enough to find a mate, healthy enough to reproduce, and sufficiently blessed by fate and circumstances to live long enough to do so. Not one of your pertinent ancestors was squashed, devoured, drowned, starved, stuck fast, untimely wounded or otherwise deflected from its life’s quest of delivering a tiny charge of genetic material to the right partner at the right moment to perpetuate the only possible sequence of hereditary combinations that could result – eventually, astoundingly, and all too briefly – in you.

Look everywhere. There are miracles and curiosities to fascinate and intrigue for many lifetimes: the intricacies of nature and everything in the world and universe around us from the miniscule to the infinite; physical, chemical and biological functionality; consciousness, intelligence and the ability to learn; evolution, and the imperative for life; beauty and other abstract interpretations; language and other forms of communication; how we make our way here and develop social patterns of culture and meaningfulness; how we organise ourselves and others; moral imperatives; the practicalities of survival and all the embellishments we pile on top; thought, beliefs, logic, intuition, ideas; inventing, creating, information, knowledge; emotions, sensations, experience, behaviour. We are each unique individuals arising from a combination of genetic, inherited, and learned information, all of which can be extremely fallible. Things taught to us when we are young are quite deeply ingrained. Obviously some of it (like don’t stick your finger in a wall socket) is very useful, but some of it is only opinion – an amalgamation of views from people you just happen to have had contact with. A bit later on we have access to lots of other information via books, media, internet etc, but it is important to remember that most of this is still just opinion, and often biased. Even subjects such as history are presented according to the presenter’s or author’s viewpoint, and science is continually changing. Newspapers and TV tend to cover news in the way that is most useful to them (and their funders/advisors), Research is also subject to the decisions of funders and can be distorted by business interests. Pretty much anyone can say what they want on the internet, so our powers of discernment need to be used to a great degree there too. Not one of us can have a completely objective view as we cannot possibly have access to, and filter, all knowledge available, so we must accept that our views are bound to be subjective. Our understanding and responses are all very personal, and our views extremely varied. We tend to make each new thing fit in with the picture we have already started in our heads, but we often have to go back and adjust the picture if we want to be honest about our view of reality as we continually expand it. We are taking in vast amounts of information from others all the time, so need to ensure we are processing that to develop our own true reflection of who we are.

If the history of the last century taught us the dangers of empowering governments to determine genetic “fitness” (i.e., which person fits within the triangle, and who lives outside it), then the question that confronts our current era is what happens when this power devolves to the individual. It is a question that requires us to balance the desires of the individual— to carve out a life of happiness and achievement, without undue suffering— with the desires of a society that, in the short term, may be interested only in driving down the burden of disease and the expense of disability. And operating silently in the background is a third set of actors: our genes themselves, which reproduce and create new variants oblivious of our desires and compulsions— but, either directly or indirectly, acutely or obliquely, influence our desires and compulsions. Speaking at the Sorbonne in 1975, the cultural historian Michel Foucault once proposed that “a technology of abnormal individuals appears precisely when a regular network of knowledge and power has been established.” Foucault was thinking about a “regular network” of humans. But it could just as easily be a network of genes.

The double-helix has solved all three of the major challenges of genetic physiology using ingenious variations on the same theme. Mirror-image chemicals are used to generate mirror-image chemicals, reflections used to reconstruct the orginal. Pairs used to maintain the fidelity and fixity of information. "Monet is but an eye," Cezanne once said of his friend, "but, God, what an eye." DNA, by the same logic, is but a chemical-but, God, what a chemical.

Marrying cousins was astoundingly common into the nineteenth century, and nowhere is this better illustrated than with the Darwins and their cousins the Wedgwoods (of pottery fame). Charles married his first cousin Emma Wedgwood, daughter of his beloved Uncle Josiah. Darwin's sister Caroline, meanwhile, married Josiah Wedgwood III, Emma's brother and the Darwin siblings' joint first cousin. Another of Emma's brothers, Henry, married not a Darwin but a first cousin from another branch of his own Wedgwood family, adding another strand to the family's wondrously convoluted genetics. Finally, Charles Langton, who was not related to either family, first married Charlotte Wedgwood, another daughter of Josiah and cousin of Charles, and then upon Charlotte's death married Darwin's sister Emily, thus becoming, it seems, his sister-in-law's sister-in-law's husband and raising the possibility that any children of the union would be their own first cousins.

After Christians had spent years destroying books and libraries, St. John Chrysostom, the pre-eminent Greek Father of the Church, proudly declared, “Every trace of the old philosophy and literature of the ancient world has vanished from the face of the earth” – Helen Ellerbe (The Dark Side of Christian History) Pagan temples were either closed, transformed into Christian shrines or demolished. Their properties were summarily added to the Church’s patrimony. The wealth of sundry religions were mercilessly expropriated, their clergy dismissed or persecuted, when not civilly or even physically obliterated – Avro Manhattan (Vatican Billions)

Why did I revive that old word? Because with the notion of habitus you can refer to something that is close to what is suggested by the idea of habit, while differing from it in one important respect. The habitus, as the word implies, is that which one has acquired, but which has become durably incorporated in the body in the form of permanent dispositions. So the term constantly reminds us that it refers to something historical, linked to individual history, and that it belongs to a genetic mode of thought, as opposed to essentialist modes of thought (like the notion of competence which is part of the Chomskian lexis). Moreover, by habitus the Scholastics also meant something like a property, a capital. And indeed, the habitus is a capital, but one which, because it is embodied, appears as innate.

She cried until the sun started to set, until the birds settled into their trees. She’d have to tell her siblings he was gone. She felt embarrassed, thinking of how excited she’d been to take them to Bora-Bora. She grew cold, sitting outside in Brandon’s underwear. And then she stood up and dried her eyes. And she thought of June. She’d lived this all before, of course. Watching her mother go through it. Family histories repeat, Nina thought. For a moment, she wondered if it was pointless to try to escape it. Maybe our parents’ lives are imprinted within us, maybe the only fate there is is the temptation of reliving their mistakes. Maybe, try as we might, we will never be able to outrun the blood that runs through our veins. Or. Or maybe we are free the moment we’re born. Maybe everything we’ve ever done is by our own hands.

Sturtevant’s rudimentary genetic map would foreshadow the vast and elaborate efforts to map genes along the human genome in the 1990s. By using linkage to establish the relative positions of genes on chromosomes, Sturtevant would also lay the groundwork for the future cloning of genes tied to complex familial diseases, such as breast cancer, schizophrenia, and Alzheimer’s disease. In about twelve hours, in an undergraduate dorm room in New York, he had poured the foundation for the Human Genome Project.

The meaning of sex is illustrated by two eponymous heroes of British history, King Edward VII (who flourished in the years before the First World War) and the King Edward variety of potato which has fed the British working class for almost as long). The potato, unlike the royal family, reproduces asexually. Every King Edward potato is identical to every other and each on has the same set of genes as the hoary ancestor of all potatoes bearing that name. This is convenient for the farmer and the grocer, which is why sex is not encouraged among potatoes.

The only answer that I can give to this problem is based on Darwin’s principle of natural selection. The idea is that in any population of self-reproducing organisms, there will be variations in the genetic material and upbringing that different individuals have. These differences will mean that some individuals are better able than others to draw the right conclusions about the world around them and to act accordingly. These individuals will be more likely to survive and reproduce and so their pattern of behavior and thought will come to dominate. It

The commercialization of molecular biology is the most stunning ethical event in the history of science, and it has happened with astonishing speed. For four hundred years since Galileo, science has always proceeded as a free and open inquiry into the workings of nature. Scientists have always ignored national boundaries, holding themselves above the transitory concerns of politics and even wars. Scientists have always rebelled against secrecy in research, and have even frowned on the idea of patenting their discoveries, seeing themselves as working to the benefit of all mankind. And for many generations, the discoveries of scientists did indeed have a peculiarly selfless quality... Suddenly it seemed as if everyone wanted to become rich. New companies were announced almost weekly, and scientists flocked to exploit genetic research... It is necessary to emphasize how significant this shift in attitude actually was. In the past, pure scientists took a snobbish view of business. They saw the pursuit of money as intellectually uninteresting, suited only to shopkeepers. And to do research for industry, even at the prestigious Bell or IBM labs, was only for those who couldn't get a university appointment. Thus the attitude of pure scientists was fundamentally critical toward the work of applied scientists, and to industry in general. Their long-standing antagonism kept university scientists free of contaminating industry ties, and whenever debate arose about technological matters, disinterested scientists were available to discuss the issues at the highest levels. But that is no longer true. There are very few molecular biologists and very few research institutions without commercial affiliations. The old days are gone. Genetic research continues, at a more furious pace than ever. But it is done in secret, and in haste, and for profit.

Since the dawn of time, several billion human (or humanlike) beings have lived, each contributing a little genetic variability to the total human stock. Out of this vast number, the whole of our understanding of human prehistory is based on the remains, often exceedingly fragmentary, of perhaps five thousand individuals. You could fit it all into the back of a pickup truck if you didn't mind how much you jumbled everything up, Ian Tattersall, the bearded and friendly curator of anthropology at the American Museum of Natural History in New York, replied when I asked him the size of the total world archive of hominid and early human bones. The shortage wouldn't be so bad if the bones were distributed evenly through time and space, but of course they are not. They appear randomly, often in the most tantalizing fashion. Homo erectus walked the Earth for well over a million years and inhabited territory from the Atlantic edge of Europe to the Pacific side of China, yet if you brought back to life every Homo erectus individual whose existence we can vouch for, they wouldn't fill a school bus. Homo habilis consists of even less: just two partial skeletons and a number of isolated limb bones. Something as short-lived as our own civilization would almost certainly not be known from the fossil record at all. In Europe, Tattersall offers by way of illustration, you've got hominid skulls in Georgia dated to about 1.7 million years ago, but then you have a gap of almost a million years before the next remains turn up in Spain, right on the other side of the continent, and then you've got another 300,000-year gap before you get a Homo heidelbergensis in Germany and none of them looks terribly much like any of the others. He smiled. It's from these kinds of fragmentary pieces that you're trying to work out the histories of entire species. It's quite a tall order. We really have very little idea of the relationships between many ancient species which led to us and which were evolutionary dead ends. Some probably don't deserve to be regarded as separate species at all.

Consider the genesis of a single-celled embryo produced by the fertilization of an egg by a sperm. The genetic material of this embryo comes from two sources: paternal genes (from sperm) and maternal genes (from eggs). But the cellular material of the embryo comes exclusively from the egg; the sperm is no more than a glorified delivery vehicle for male DNA—a genome equipped with a hyperactive tail. Aside from proteins, ribosomes, nutrients, and membranes, the egg also supplies the embryo with specialized structures called mitochondria. These mitochondria are the energy-producing factories of the cell; they are so anatomically discrete and so specialized in their function that cell biologists call them “organelles”—i.e., mini-organs resident within cells. Mitochondria, recall, carry a small, independent genome that resides within the mitochondrion itself—not in the cell’s nucleus, where the twenty-three pairs of chromosomes (and the 21,000-odd human genes) can be found. The exclusively female origin of all the mitochondria in an embryo has an important consequence. All humans—male or female—must have inherited their mitochondria from their mothers, who inherited their mitochondria from their mothers, and so forth, in an unbroken line of female ancestry stretching indefinitely into the past. (A woman also carries the mitochondrial genomes of all her future descendants in her cells; ironically, if there is such a thing as a “homunculus,” then it is exclusively female in origin—technically, a “femunculus”?) Now imagine an ancient tribe of two hundred women, each of whom bears one child. If the child happens to be a daughter, the woman dutifully passes her mitochondria to the next generation, and, through her daughter’s daughter, to a third generation. But if she has only a son and no daughter, the woman’s mitochondrial lineage wanders into a genetic blind alley and becomes extinct (since sperm do not pass their mitochondria to the embryo, sons cannot pass their mitochondrial genomes to their children). Over the course of the tribe’s evolution, tens of thousands of such mitochondrial lineages will land on lineal dead ends by chance, and be snuffed out. And here is the crux: if the founding population of a species is small enough, and if enough time has passed, the number of surviving maternal lineages will keep shrinking, and shrinking further, until only a few are left. If half of the two hundred women in our tribe have sons, and only sons, then one hundred mitochondrial lineages will dash against the glass pane of male-only heredity and vanish in the next generation. Another half will dead-end into male children in the second generation, and so forth. By the end of several generations, all the descendants of the tribe, male or female, might track their mitochondrial ancestry to just a few women. For modern humans, that number has reached one: each of us can trace our mitochondrial lineage to a single human female who existed in Africa about two hundred thousand years ago. She is the common mother of our species. We do not know what she looked like, although her closest modern-day relatives are women of the San tribe from Botswana or Namibia. I find the idea of such a founding mother endlessly mesmerizing. In human genetics, she is known by a beautiful name—Mitochondrial Eve.

As this book will show, objectively defined races simply do not exist. Even Arthur Mourant realized that fact nearly fifty years ago, when he wrote: 'Rather does a study of blood groups show a heterogeneity in the proudest nation and support the view that the races of the present day are but temporary integrations in the constant process of . . . mixing that marks the history of every living species.' The temptation to classify the human species into categories which have no objective basis is an inevitable but regrettable consequence of the gene frequency system when it is taken too far. For several years the study of human genetics got firmly bogged down in the intellectually pointless (and morally dangerous) morass of constructing ever more detailed classifications of human population groups.

Every genetic “illness” is a mismatch between an organism’s genome and its environment. In some cases, the appropriate medical intervention to mitigate a disease might be to alter the environment to make it “fit” an organismal form (building alternative architectural realms for those with dwarfism; imagining alternative educational landscapes for children with autism). In other cases, conversely, it might mean changing genes to fit environments. In yet other cases, the match may be impossible to achieve: the severest forms of genetic illnesses, such as those caused by nonfunction of essential genes, are incompatible with all environments. It is a peculiar modern fallacy to imagine that the definitive solution to illness is to change nature—i.e., genes—when the environment is often more malleable. 10.

We are the expression of millions of prior circumstances that have all come together to shape us in the present moment. Our economic and social background, our past associations and conversations, our culture, our family history, our genetics—they’ve all had a profound role in creating the person we are today. Zen master Thich Nhat Hahn calls this “interbeing.” If you are a poet, you will see clearly that there is a cloud floating in this sheet of paper. Without a cloud there will be no water; without water, the trees cannot grow; and without trees, you cannot make paper. So the cloud is in here. The existence of this page is dependent upon the existence of a cloud. Paper and cloud are so close.

McKusick's belief in this paradigm-the focus on disability rather than abnormalcy-was actualized in the treatment of patients in his clinic. Patients with dwarfism, for instance, were treated by an interdisciplinary team of genetic counselors, neurologists, orthopedic surgeons, nurses, and psychiatrists trained to focus on specific disabilities of persons with short stature. Surgical interventions were reserved to correct specific deformities as they arose. The goal was not to restore "normalcy"-but vitality, joy, and function. McKusic had rediscovered the founding principles of modern genetics in the realm of human pathology. In humans as in wild flies, genetic variations abounded. Here too genetic variants, environments, and gene-environment interactions ultimately collaborated to cause phenotypes-except in this case, the "phenotype" in question was disease. Here too some genes had partial penetrance and widely variable expressivity. One gene could cause many diseases, and one disease could be caused by many genes. And here too "fitness" could not be judged in absolutes. Rather the lack of fitness-illness [italicized, sic] in colloquial terms- was defined by the relative mismatch between an organism and environment.

I want them to lose themselves with me. In me. I kiss them like my only job is to make them feel that this is worth their time. So they leave with a smile, not a regret. I want them to smile and believe it because I know how good the exhale feels. The feeling that makes you re-think your future that I could one day be a father to your children. I want you to believe that even if it's not true. Because despite my flaws and shortcomings, genetics and history, I want you to leave with an ideal. A dream of what could be. A perfect moment. And I know I could never measure up to the man you think I am. But for that evening, in that bed, legs entwined while the warm post-glow sweat cools... I want to be worth it. In your eyes, I hope I'm worth it.

In the United States both scholars and the general public have been conditioned to viewing human races as natural and separate divisions within the human species based on visible physical differences. With the vast expansion of scientific knowledge in this century, however, it has become clear that human populations are not unambiguous, clearly demarcated, biologically distinct groups. Evidence from the analysis of genetics (e.g. DNA) indicates that most physical variation, about 94%, lies within so-called racial groups. Conventional geographic "racial" groupings differ from one another only in about 6% of their genes. This means that there is greater variation within "racial" groups than between them. In neighboring populations there is much overlapping of genes and their phenotypic (physical) expressions. Throughout history whenever different groups have come into contact, they have interbred. The continued sharing of genetic materials has maintained all of humankind as a single species.

The appearance of new ways of thinking and communicating, between 70,000 and 30,000 years ago, constitutes the Cognitive Revolution. What caused it? We’re not sure. The most commonly believed theory argues that accidental genetic mutations changed the inner wiring of the brains of Sapiens, enabling them to think in unprecedented ways and to communicate using an altogether new type of language. We might call it the Tree of Knowledge mutation. Why did it occur in Sapiens DNA rather than in that of Neanderthals? It was a matter of pure chance, as far as we can tell. But it’s more important to understand the consequences of the Tree of Knowledge mutation than its causes. What was so special about the new Sapiens language that it enabled us to conquer the world?* It was not the first language. Every animal has some kind of language.

The experiment changed Sally’s life. In the following days she realised she has been through a ‘near-spiritual experience…what defined the experience was not feeling smarter or learning faster: the thing that made the earth drop out from under my feet was that for the first time in my life, everything in my head finally shut up…My brain without self-doubt was a revelation. There was suddenly this incredible silence in my head…I hope you can sympathise with me when I tell you that the thing I wanted most acutely for the weeks following my experience was to go back and strap on those electrodes. I also started to have a lot of questions. Who was I apart from the angry bitter gnomes that populate my mind and drive me to failure because I’m too scared to try? And where did those voices come from?’7 Some of those voices repeat society’s prejudices, some echo our personal history, and some articulate our genetic legacy. All of them together, says Sally, create an invisible story that shapes our conscious decisions in ways we seldom grasp. What would happen if we could rewrite our inner monologues, or even silence them completely on occasion? 8

When I learned my mom was going to die of cancer at the age of forty-five, I felt the same way. I didn’t even believe in God, but I still felt that he owed me something. I had the gall to think How dare he? I couldn’t help myself. I’m a selfish brute. I wanted what I wanted and I expected it to be given to me by a God in whom I had no faith. Because mercy had always more or less been granted me, I assumed it always would be. But it wasn’t. It wasn’t granted to my friend whose eighteen-year-old daughter was killed by a drunk driver either. Nor was it granted to my other friend who learned her baby is going to die of a genetic disorder in the not-distant future. Nor was it granted to my former student whose mother was murdered by her father before he killed himself. It was not granted to all those people who were in the wrong place at the wrong time when they came up against the wrong virus or military operation or famine or carcinogenic or genetic mutation or natural disaster or maniac. Countless people have been devastated for reasons that cannot be explained or justified in spiritual terms. To do as you are doing in asking If there were a God, why would he let my little girl have to have possibly life-threatening surgery?— understandable as that question is—creates a false hierarchy of the blessed and the damned. To use our individual good or bad luck as a litmus test to determine whether or not God exists constructs an illogical dichotomy that reduces our capacity for true compassion. It implies a pious quid pro quo that defies history, reality, ethics, and reason. It fails to acknowledge that the other half of rising—the very half that makes rising necessary— is having first been nailed to the cross. That

When scientists underestimate complexity, they fall prey to the perils of unintended consequences. The parables of such scientific overreach are well-known: foreign animals, introduced to control pests, become pests in their own right; the raising of smokestacks, meant to alleviate urban pollution, releases particulate effluents higher in the air and exacerbates pollution; stimulating blood formation, meant to prevent heart attacks, thickens the blood and results in an increased risk of blood clots in the heart. But when nonscientists overestimate [italicized, sic] complexity- 'No one can possibly crack this [italicized, sic] code" - they fall into the trap of unanticipated consequences. In the early 1950s , a common trope among some biologists was that the genetic code would be so context dependent- so utterly determined by a particular cell in a particular organism and so horribly convoluted- that deciphering it would be impossible. The truth turned out to be quite the opposite: just one molecule carries the code, and just one code pervades the biological world. If we know the code, we can intentionally alter it in organisms, and ultimately in humans. Similarly, in the 1960s, many doubted that gene-cloning technologies could so easily shuttle genes between species. by 1980, making a mammalian protein in a bacterial cell, or a bacterial protein in a mammalian cell, was not just feasible, it was in Berg's words, rather "ridiculously simple." Species were specious. "Being natural" was often "just a pose.

We do know that humans got hit hard by the Toba Super Volcano. We were on the brink of extinction. That caused what population geneticists call a ‘population bottleneck.’ Some researchers believe that this bottleneck caused a small group of humans to evolve, to survive through mutation. These mutations could have led to humanity’s exponential explosion in intelligence. There’s genetic evidence for it. We know that every human being on the planet is directly descended from one man who lived in Africa around sixty thousand years ago—a person we geneticists call Y-Chromosomal Adam. In fact, everyone outside of Africa is descended from a small band of humans, maybe as few as one hundred, that left Africa about 50,000 years ago. Essentially, we’re all members of a small tribe that walked out of Africa after Toba and took over the planet. That tribe was significantly more intelligent than any other hominids in history.

But the history of Hopkins Hospital certainly isn’t pristine when it comes to black patients. In 1969, a Hopkins researcher used blood samples from more than 7,000 neighborhood children—most of them from poor black families—to look for a genetic predisposition to criminal behavior. The researcher didn’t get consent. The American Civil Liberties Union filed suit claiming the study violated the boys’ civil rights and breached confidentiality of doctor-patient relationships by releasing results to state and juvenile courts. The study was halted, then resumed a few months later using consent forms. And in the late nineties, two women sued Hopkins, claiming that its researchers had knowingly exposed their children to lead, and hadn’t promptly informed them when blood tests revealed that their children had elevated lead levels—even when one developed lead poisoning. The research was part of a study examining lead abatement methods, and all families involved were black. The researchers had treated several homes to varying degrees, then encouraged landlords to rent those homes to families with children so they could then monitor the children’s lead levels. Initially, the case was dismissed. On appeal, one judge compared the study to Southam’s HeLa injections, the Tuskegee study, and Nazi research, and the case eventually settled out of court. The Department of Health and Human Services launched an investigation and concluded that the study’s consent forms “failed to provide an adequate description” of the different levels of lead abatement in the homes.

When the British invaders confronted the Iroquois on the east coast of North America, the British were able to draw upon technology, science, and other cultural developments from China, India, and Egypt, not to mention various other peoples from continental Europe. But the Iroquois could not draw upon the cultural developments of the Aztecs or Incas, who remained unknown to them, though located only a fraction of the distance away as China is from Britain. While the immediate confrontation was between the British settlers and the Iroquois, the cultural resources mobilized on one side represented many more cultures from many more societies around the world. It was by no means a question of the genetic or even cultural superiority of the British by themselves, as compared to the Iroquois, for the British were by no means by themselves. They had the advantage of centuries of cultural diffusion from numerous sources, scattered over thousands of miles.

The Lutz heck that emerges from his writings and actions drifted like a weather vane: charming when need be, cold-blooded when need be, tigerish or endearing, depending on his goal. Still, it is surprising that Heck the zoologist chose to ignore the accepted theory of hybrid vigor: that interbreeding strengthens a bloodline. He must have known that mongrels enjoy better immune systems and have more tricks up their genetic sleeves, while in a closely knit species, however "perfect," any illness that kills one animal threatens to wipe out all the others, which is why zoos keep careful studbooks of endangered animals such as cheetahs and forest bison and try to mate them advantageously. In any case, in the distant past, long before anyone was recognizably Aryan, our ancestors shared the world with other flavors of hominids, and interbreeding among neighbors often took place, producing hardier, nastier offspring who thrived. All present-day humans descend from that robust, talkative mix, specifically from a genetic bottleneck of only about one hundred individuals. A 2006 study of mitochondrial DNA tracks Ashkenazi Jews (about 92 percent of the world’s Jews in 1931) back to four women, who migrated from the Near East to Italy in the second and third centuries. All of humanity can be traced back to the gene pool of one person, some say to a man, some a woman. It’s hard to imagine our fate being as iffy as that, be we are natural wonders.

The more I know the human being, the more I cling to animal nature. Mention poem 2013 Since its beginnings, the human being has been a complex and enigmatic being, capable of great achievements and feats, and at the same time, of the most cruel and vile acts. There is no doubt that our species is one of the most evolved and sophisticated of the planet, but at what cost? What is behind our apparent superiority? When we observe human behavior, we can see that it hides a mixture of animal instincts and rational thoughts. Although human beings take pride in our ability for critical thinking and reflection, We are also emotional, impulsive and visceral beings. And it is precisely this duality that makes us so different from animals. that cohabit this planet with us. It is often difficult for us to understand the nature of animals, because we cannot access their internal world. However, what we can say is that animals are transparent beings, His actions are always a consequence of his instincts, not from premeditated thoughts or complex emotions. For animals, living is following their instinct, something that allows them to act quickly and effectively in situations of danger or threat. Animals are beings in balance with their environment, They don't feel the need to constantly change, nor to think beyond the here and now. On the other hand, we have human beings, beings capable of conceiving abstract thoughts, create works of art, invent technologies and, at the same time, of destroying the environment, oppressing other human beings and commit acts of extreme cruelty. The human being is a complex, contradictory being, capable of loving and hating, forgiving and punishing, healing and destroying. We are creatures of light and darkness, in a constant search for balance between both parties. But what is behind our duality as human beings? Why are we capable of the worst acts of destruction and cruelty? If we look back at the history of humanity, we can see that our genetic patterns are impregnated of violence, war and resentment. History has been a constant parade of wars and conflicts, each one more brutal than the last. This being the only way in which many cultures they have found to impose their ideas or consolidate power. It is precisely here that the idea is born that the creators of humanity They have intoxicated us with the yoke of evil. Who are these forgers? They are the same societies, cultures, religions, policies, which have used violence, war and resentment as a tool to impose their desires and ideals on others. This is the curse that we have dragged like chains since long ago, that of a genetic pattern that drags us towards violence and war. It is true that, as human beings, we can choose our own paths, our own decisions, and not fall into the trap of cruelty and evil. However, it is also true that we carry within us an ancestral burden that is difficult to overcome. What will the most advanced civilizations in the universe think of us? Will we be violent and hateful beings for them? Or will we be beings like animals, in balance with our environment? The answer is not easy, since it remains an unknown. if we are able to overcome our animal instincts and embrace only the best of our humanity. The key to this lies in becoming aware of our own duality, to recognize that we carry both light and darkness within us, and make a real effort to choose the best of ourselves, instead of letting ourselves be carried away by our internal evil.

By Mendel’s time, plant breeding had progressed to a point where every region boasted dozens of local varieties of peas, not to mention beans, lettuce, strawberries, carrots, wheat, tomatoes, and scores of other crops. People may not have known about genetics, but everyone understood that plants (and animals) could be changed dramatically through selective breeding. A single species of weedy coastal mustard, for example, eventually gave rise to more than half a dozen familiar European vegetables. Farmers interested in tasty leaves turned it into cabbages, collard greens, and kale. Selecting plants with edible side buds and flower shoots produced Brussels sprouts, cauliflower, and broccoli, while nurturing a fattened stem produced kohlrabi. In some cases, improving a crop was as simple as saving the largest seeds, but other situations required real sophistication. Assyrians began meticulously hand-pollinating date palms more than 4,000 years ago, and as early as the Shang Dynasty (1766–1122 BC), Chinese winemakers had perfected a strain of millet that required protection from cross-pollination. Perhaps no culture better expresses the instinctive link between growing plants and studying them than the Mende people of Sierra Leone, whose verb for “experiment” comes from the phrase “trying out new rice.

The problem with racial discrimination, though, is not the inference of a person's race from their genetic characteristics. It is quite the opposite: it is the inference of a person's characteristics from their race. The question is not, can you, given an individual's skin color, hair texture, or language, infer something about their ancestry or origin. That is a question of biological systematics -- of lineage, taxonomy, of racial geography, of biological discrimination. Of course you can -- and genomics as vastly refined that inference. You can scan any individual genome and infer rather deep insights about a person's ancestry, or place of origin. But the vastly more controversial question is the converse: Given a racial identity -- African or Asian, say -- can you infer anything about an individual's characteristics: not just skin or hair color, but more complex features, such as intelligence, habits, personality, and aptitude? /I/ Genes can certainly tell us about race, but can race tell us anything about genes? /i/ To answer this question, we need to measure how genetic variation is distributed across various racial categories. Is there more diversity _within_ races or _between_ races? Does knowing that someone is of African versus European descent, say, allow us to refine our understanding of their genetic traits, or their personal, physical, or intellectual attributes in a meaningful manner? Or is there so much variation within Africans and Europeans that _intraracial_ diversity dominates the comparison, thereby making the category "African" or "European" moot? We now know precise and quantitative answers to these questions. A number of studies have tried to quantify the level of genetic diversity of the human genome. The most recent estimates suggest that the vast proportion of genetic diversity (85 to 90 percent) occurs _within_ so-called races (i.e., within Asians or Africans) and only a minor proportion (7 percent) within racial groups (the geneticist Richard Lewontin had estimated a similar distribution as early as 1972). Some genes certainly vary sharply between racial or ethnic groups -- sickle-cell anemia is an Afro-Caribbean and Indian disease, and Tay-Sachs disease has a much higher frequency in Ashkenazi Jews -- but for the most part, the genetic diversity within any racial group dominates the diversity between racial groups -- not marginally, but by an enormous amount. The degree of interracial variability makes "race" a poor surrogate for nearly any feature: in a genetic sense, an African man from Nigria is so "different" from another man from Namibia that it makes little sense to lump them into the same category.

During the war, Monod had joined the Communist Party as a matter of expediency, so that he could join the FTP. But he developed reservations about the Communists’ intolerance of other political views and quietly quit the Party after the war, at a time when many fellow citizens were joining. That might have been the end of Monod’s involvement with Communism, were it not for bizarre developments in the sphere of Soviet science. In the summer of 1948, Trofim Denisovich Lysenko, Joseph Stalin’s anointed czar of Soviet agriculture, launched a broad attack on the science of genetics. Lysenko believed that virtually any modification could be made rapidly and permanently to any plant or animal and passed on to its offspring. His belief, while consistent with Soviet doctrine that nature and man could be shaped in any way and were unconstrained by history or heredity, flew in the face of the principles of genetics that had been established over the previous fifty years. Nevertheless, Lysenko demanded that classical genetics, and its supporters, be purged from Soviet biology. Lysenko’s outrageous statements were heralded in Communist-run newspapers in France. Monod responded with a devastating critique that ran on the front page of Combat. Monod exposed Lysenko’s stance on genetics as antiscientific dogma and decried Lysenko’s power as a demonstration of “ideological terrorism” in the Soviet Union. The public scrutiny damaged the credibility of Soviet socialism in France. The episode thrust Monod into the public eye and made him resolve to “make his life’s goal a crusade against antiscientific, religious metaphysics, whether it be from Church or State.

Had she been able to listen to her body, the true Virginia would certainly have spoken up. In order to do so, however, she needed someone to say to her: “Open your eyes! They didn’t protect you when you were in danger of losing your health and your mind, and now they refuse to see what has been done to you. How can you love them so much after all that?” No one offered that kind of support. Nor can anyone stand up to that kind of abuse alone, not even Virginia Woolf. Malcolm Ingram, the noted lecturer in psychological medicine, believed that Woolf’s “mental illness” had nothing to do with her childhood experiences, and her illness was genetically inherited from her family. Here is his opinion as quoted on the Virginia Woolf Web site: As a child she was sexually abused, but the extent and duration is difficult to establish. At worst she may have been sexually harassed and abused from the age of twelve to twenty-one by her [half-]brother George Duckworth, [fourteen] years her senior, and sexually exploited as early as six by her other [half-] brother… It is unlikely that the sexual abuse and her manic-depressive illness are related. However tempting it may be to relate the two, it must be more likely that, whatever her upbringing, her family history and genetic makeup were the determining factors in her mood swings rather than her unhappy childhood [italics added]. More relevant in her childhood experience is the long history of bereavements that punctuated her adolescence and precipitated her first depressions.3 Ingram’s text goes against my own interpretation and ignores a large volume of literature that deals with trauma and the effects of childhood abuse. Here we see how people minimize the importance of information that might cause pain or discomfort—such as childhood abuse—and blame psychiatric disorders on family history instead. Woolf must have felt keen frustration when seemingly intelligent and well-educated people attributed her condition to her mental history, denying the effects of significant childhood experiences. In the eyes of many she remained a woman possessed by “madness.” Nevertheless, the key to her condition lay tantalizingly close to the surface, so easily attainable, and yet neglected. I think that Woolf’s suicide could have been prevented if she had had an enlightened witness with whom she could have shared her feelings about the horrors inflicted on her at such an early age. But there was no one to turn to, and she considered Freud to be the expert on psychic disorders. Here she made a tragic mistake. His writings cast her into a state of severe uncertainty, and she preferred to despair of her own self rather than doubt the great father figure Sigmund Freud, who represented, as did her family, the system of values upheld by society, especially at the time.   UNFORTUNATELY,

How long will the Gilgamesh Project – the quest for immortality – take to complete? A hundred years? Five hundred years? A thousand years? When we recall how little we knew about the human body in 1900, and how much knowledge we have gained in a single century, there is cause for optimism. Genetic engineers have recently managed to double the average life expectancy of Caenorhabditis elegans worms.12 Could they do the same for Homo sapiens? Nanotechnology experts are developing a bionic immune system composed of millions of nano-robots, who would inhabit our bodies, open blocked blood vessels, fight viruses and bacteria, eliminate cancerous cells and even reverse ageing processes.13 A few serious scholars suggest that by 2050, some humans will become a-mortal (not immortal, because they could still die of some accident, but a-mortal, meaning that in the absence of fatal trauma their lives could be extended indefinitely). Whether or not Project Gilgamesh succeeds, from a historical perspective it is fascinating to see that most late-modern religions and ideologies have already taken death and the afterlife out of the equation. Until the eighteenth century, religions considered death and its aftermath central to the meaning of life. Beginning in the eighteenth century, religions and ideologies such as liberalism, socialism and feminism lost all interest in the afterlife. What, exactly, happens to a Communist after he or she dies? What happens to a capitalist? What happens to a feminist? It is pointless to look for the answer in the writings of Marx, Adam Smith or Simone de Beauvoir. The only modern ideology that still awards death a central role is nationalism. In its more poetic and desperate moments, nationalism promises that whoever dies for the nation will for ever live in its collective memory. Yet this promise is so fuzzy that even most nationalists do not really know what to make of it. The

And by the early 1970s our little parable of Sam and Sweetie is exactly what happened to the North American Golden Retriever. One field-trial dog, Holway Barty, and two show dogs, Misty Morn’s Sunset and Cummings’ Gold-Rush Charlie, won dozens of blue ribbons between them. They were not only gorgeous champions; they had wonderful personalities. Consequently, hundreds of people wanted these dogs’ genes to come into their lines, and over many matings during the 1970s the genes of these three dogs were flung far and wide throughout the North American Golden Retriever population, until by 2010 Misty Morn’s Sunset alone had 95,539 registered descendants, his number of unregistered ones unknown. Today hundreds of thousands of North American Golden Retrievers are descended from these three champions and have received both their sweet dispositions and their hidden time bombs. Unfortunately for these Golden Retrievers, and for the people who love them, one of these time bombs happens to be cancer. To be fair, a so-called cancer gene cannot be traced directly to a few famous sires, but using these sires so often increases the chance of recessive genes meeting—for good and for ill. Today, in the United States, 61.4 percent of Golden Retrievers die of cancer, according to a survey conducted by the Golden Retriever Club of America and the Purdue School of Veterinary Medicine. In Great Britain, a Kennel Club survey found almost exactly the same result, if we consider that those British dogs—loosely diagnosed as dying of “old age” and “cardiac conditions” and never having been autopsied—might really be dying of a variety of cancers, including hemangiosarcoma, a cancer of the lining of the blood vessels and the spleen. This sad history of the Golden Retriever’s narrowing gene pool has played out across dozens of other breeds and is one of the reasons that so many of our dogs spend a lot more time in veterinarians’ offices than they should and die sooner than they might. In genetic terms, it comes down to the ever-increasing chance that both copies of any given gene are derived from the same ancestor, a probability expressed by a number called the coefficient of inbreeding. Discovered in 1922 by the American geneticist Sewall Wright, the coefficient of inbreeding ranges from 0 to 100 percent and rises as animals become more inbred.

What is it about the ancients,’ Pinker asks at one point, ‘that they couldn’t leave us an interesting corpse without resorting to foul play?’ There is an obvious response to this: doesn’t it rather depend on which corpse you consider interesting in the first place? Yes, a little over 5,000 years ago someone walking through the Alps left the world of the living with an arrow in his side; but there’s no particular reason to treat Ötzi as a poster child for humanity in its original condition, other than, perhaps, Ötzi suiting Pinker’s argument. But if all we’re doing is cherry-picking, we could just as easily have chosen the much earlier burial known to archaeologists as Romito 2 (after the Calabrian rock-shelter where it was found). Let’s take a moment to consider what it would mean if we did this. Romito 2 is the 10,000-year-old burial of a male with a rare genetic disorder (acromesomelic dysplasia): a severe type of dwarfism, which in life would have rendered him both anomalous in his community and unable to participate in the kind of high-altitude hunting that was necessary for their survival. Studies of his pathology show that, despite generally poor levels of health and nutrition, that same community of hunter-gatherers still took pains to support this individual through infancy and into early adulthood, granting him the same share of meat as everyone else, and ultimately according him a careful, sheltered burial.15 Neither is Romito 2 an isolated case. When archaeologists undertake balanced appraisals of hunter-gatherer burials from the Palaeolithic, they find high frequencies of health-related disabilities – but also surprisingly high levels of care until the time of death (and beyond, since some of these funerals were remarkably lavish).16 If we did want to reach a general conclusion about what form human societies originally took, based on statistical frequencies of health indicators from ancient burials, we would have to reach the exact opposite conclusion to Hobbes (and Pinker): in origin, it might be claimed, our species is a nurturing and care-giving species, and there was simply no need for life to be nasty, brutish or short. We’re not suggesting we actually do this. As we’ll see, there is reason to believe that during the Palaeolithic, only rather unusual individuals were buried at all. We just want to point out how easy it would be to play the same game in the other direction – easy, but frankly not too enlightening.

Nobody is ever made happy by winning the lottery, buying a house, getting a promotion or even finding true love. People are made happy by one thing and one thing only – pleasant sensations in their bodies. A person who just won the lottery or found new love and jumps from joy is not really reacting to the money or the lover. She is reacting to various hormones coursing through her bloodstream and to the storm of electric signals flashing between different parts of her brain. Unfortunately for all hopes of creating heaven on earth, our internal biochemical system seems to be programmed to keep happiness levels relatively constant. There's no natural selection for happiness as such - a happy hermit's genetic line will go extinct as the genes of a pair of anxious parents get carried on to the next generation. Happiness and misery play a role in evolution only to the extent that they encourage or discourage survival and reproduction. Perhaps it's not surprising, then, that evolution has moulded us to be neither too miserable nor too happy. It enables us to enjoy a momentary rush of pleasant sensations, but these never last for ever. Sooner of later they subside and give place to unpleasant sensations. (...) Some scholars compare human biochemistry to an air-conditioning system that keeps the temperature constant, come heatwave or snowstorm. Events might momentarily change the temperature, but the air-conditioning system always returns the temperature to the same set point. Some air-conditioning systems are set at twenty-five degrees Celsius. Others are set at twenty degrees. Human happiness conditioning systems also differ from person to person. On a scale from one to ten, some people are born with a cheerful biochemical system that allows their mood to swing between levels six and ten, stabilising with time at eight. Such a person is quite happy even if she lives in an alienating big city, loses all her money in a stock-exchange crash and is diagnosed with diabetes. Other people are cursed with a gloomy biochemistry that swings between three and seven and stabilises at five. Such an unhappy person remains depressed even if she enjoys the support of a tight-knit community, wins millions in the lottery and is as healthy as an Olympic athlete (...) incapable of experiencing anything beyond level seven happiness. Her brain is simply not built for exhilaration, come what may. (...) Buying cars and writing novels do not change our biochemistry. They can startle it for a fleeting moment, but it is soon back to the set point.

Cordelia – “Why so rough?” Aral – “It’s very poor. It was the town center during the time Isolation. And it hasn’t been touched by renovation, minimal water, no electricity choked with refuse.” “Mostly human,” added Peoter tartly. “Poor?” Asked Cordelia bewildered. “No electricity? How can it be on the comm network?” “It’s not of course,” answered Vorkosigan. “Then how can anyone get their schooling?” Cordelia “They don’t.” Cordelia stared. “I don’t understand, how do they get their jobs?” “A few escape to the service, the rest prey on each other mostly.” Vorkosigan regarded her face uneasily. “Have you no poverty on Beta colony?” “Poverty? Well some people have more money than others, but no comm consuls…?” Vorkosigan was diverted from his interrogation. “Is not owning a comm consul the lowest standard of living you can imagine?” He said in wonder. “It’s the first article in the constitution! ‘Access to information shall not be abridged.’” “Cordelia, these people barely have access to food, clothing and shelter. They have a few rags and cooking pots and squat in buildings that aren’t economical to repair or tear down yet with the wind whistling through the walls.” “No air conditioning?” “No heat in the winter is a bigger problem here.” “I suppose so. You people don’t really have summer. How do they call for help when they are sick or hurt?” “What help?” Vorkosigan was growing grim. “If they’re sick they either get well or die.” “Die if we’re lucking” muttered Veoter. “You’re not joking.” She stared back and forth between the pair of them. “Why, think of all the geniuses you must missing!” “I doubt we must be missing very many from the Caravanceri.” Said Peoter dryly. “Why not? They have the same genetic compliment as you.” Cordelia pointed out the – to her -obvious. The Count went rigid. “My dear girl, they most certainly do not. My family has been Vor for nine generations.” Cordelia raised her eyebrows. “How do you know if you didn’t have the gene-typing until 80 years ago?” Both the guard commander and the footman were acquiring peculiar stuffed expressions. The footman bit his lip. “Besides,” she pointed out reasonably, “If you Vor got around half as much as those histories I’ve been reading imply. 90% of the people on this planet must have Vor blood by now. Who knows who your relatives are on your father’s side. Vorkosigan bit his napkin absently. His eyes gone crinkly with much the same expression as the footman and muttered, “Cordelia, you really can’t sit at the breakfast table and imply my ancestors were bastards. It’s a mortal insult here.” “Where should I sit? Oh I’ll never understand.