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Epidemiologists think that smallpox killed roughly one billion people during its last hundred years of activity on earth.
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Richard Preston (The Demon in the Freezer)
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Doctors generally consider smallpox to be the worst human disease. It is thought to have killed more people than any other infectious pathogen, including the Black Death of the Middle Ages. Epidemiologists think that smallpox killed roughly one billion people during its last hundred years of activity onearth.
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Richard Preston (The Demon in the Freezer)
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we could eradicate smallpox from nature, but we could not uproot the virus from the human heart
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Richard Preston (The Demon in the Freezer)
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Blood ran freely from his nose as I closed the freezer and kicked him square in the privates. I had yet to meet a living being that didn't double over when I hit them there.
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Ben Reeder (Page of Swords (The Demon's Apprentice, #2))
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Jahrling sat down at his desk and sighed. There was a landfill of papers on his desk, mostly about smallpox, and it was discouraging. On top of the heap sat a large red book with silver
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Richard Preston (The Demon in the Freezer)
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My virologist friends are always bioengineering viruses. I could see a bioengineered strain of smallpox getting into a terrorist’s hands, and that’s my fear. And then when we get a terrorist attack with smallpox, and the smallpox doesn’t respond to the vaccine, we’re in trouble.
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Richard Preston (The Demon in the Freezer)
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The hand is a symbol of humanity, part of what makes us human - the hand that carved the Parthenon, painted the hands of God and Adam on the ceiling of the Sistine Chapel, and wrote King Lear was the only hand that had known smallpox. That same hand had now given the disease to a monkey.
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Richard Preston (The Demon in the Freezer)
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Poxviruses keep herds and swarms of living things in check, preventing them from growing too large and overwhelming their habitats. Viruses are an essential part of nature. If all the viruses on the planet were to disappear, a global catastrophe would ensue, and the natural ecosystems of the earth would collapse in a spectacular crash under burgeoning populations of insects. Viruses are nature’s crowd control, and a poxvirus can thin a crowd in a hurry.
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Richard Preston (The Demon in the Freezer)
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On May 14th, 1796, Jenner scratched the arm of a boy named James Phipps, introducing into his skin a droplet of cowpox pus that he had scraped from a blister on the hand of Sarah Nelmes, a dairy worker. He called this pus “the Vaccine Virus”—the word vaccine is derived from the Latin word for cow. The boy developed a single pustule on his arm, and it healed rapidly. A few months later, Jenner scratched the boy’s arm with lethal infective pus that he had taken from a smallpox patient—today, this is called a challenge trial. The boy did not come down with smallpox. Edward Jenner had discovered and named vaccination—the practice of infecting a person with a mild or harmless virus in order to strengthen his or her immunity to a similar disease-causing virus. “It now becomes too manifest to admit of controversy, that the annihilation of the Small Pox, the most dreadful scourge of the human species, must be the final result of this practice,” Jenner wrote in 1801.
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Richard Preston (The Demon in the Freezer)
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IN THE EARLY NINETEEN SEVENTIES, a British photo retoucher named Robert Stevens arrived in south Florida to take a job at the National Enquirer, which is published in Palm Beach County. At the time, photo retouchers for supermarket tabloids used an airbrush (nowadays they use computers) to clarify news photographs of world leaders shaking hands with aliens or to give more punch to pictures of six-month-old babies who weigh three hundred pounds. Stevens was reputed to be one of the best photo retouchers in the business. The Enquirer was moving away from stories like “I Ate My Mother-in-Law’s Head,” and the editors recruited him to bring some class to the paper. They offered him much more than he made working for tabloids in Britain.
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Richard Preston (The Demon in the Freezer)
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Variola is now exotic to the human species, highly infective in humans, lethal, and difficult or impossible to cure. It is generally believed to be the most dangerous virus to the human species.
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Richard Preston (The Demon in the Freezer)
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Viruses are an essential part of nature. If all the viruses on the planet were to disappear, a global catastrophe would ensue, and the natural ecosystems of the earth would collapse in a spectacular crash.
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Richard Preston (The Demon in the Freezer)
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The DNA molecule is shaped like a twisted ladder, and the rungs of the ladder—the nucleotides—can hold vast amounts of information, the code of life. A gene is a short stretch of DNA, typically about a thousand letters long, that holds the recipe for a protein or a group of related proteins. The total assemblage of an organism’s genetic code—its full complement of DNA, comprising all its genes—is the organism’s genome.
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Richard Preston (The Demon in the Freezer)
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had a habit of wearing a jacket and tie with a white shirt when he went into the field, because he felt that a well-dressed doctor would inspire confidence in the midst of the shit terror of a smallpox outbreak.
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Richard Preston (The Demon in the Freezer)