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The procedure, not yet approved in the United States or in Europe, was a form of stem cell therapy.
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Joseph M. Chiron (Tagged: The Apocalypse)
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Nah, unless, of course, a hospital there is claiming to have some new magical stem-cell therapy to cure B. cepacia.
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Rachael Lippincott (Five Feet Apart)
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Indeed, the scientific effort to improve performance in medicine—an effort that at present gets only a miniscule portion of scientific budgets—can arguably save more lives in the next decade than bench science, more lives than research on the genome, stem cell therapy, cancer vaccines, and all the other laboratory work we hear about in the news.
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Atul Gawande (Better: A Surgeon's Notes on Performance)
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One thing I am certain of, however, is that cell therapy of some kind—it might involve stem cells or CAR T—will eventually overcome cancer and other diseases of the brain.
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Rahul Jandial (Life Lessons From A Brain Surgeon: Practical Strategies for Peak Health and Performance)
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The cure for HIV?” “In 2007, a man named Timothy Ray Brown, known later as the Berlin patient, was cured of HIV. Brown was diagnosed with acute myeloid leukemia. His HIV-positive status complicated his treatment. During chemotherapy, he battled sepsis, and his physicians had to explore less traditional approaches. His hematologist, Dr. Gero Hutter, decided on a stem cell therapy: a full bone marrow transplant. Hutter actually passed over the matched bone marrow donor for a donor with a specific genetic mutation: CCR5-Delta 32. CCR5-Delta 32 makes cells immune to HIV.” “Incredible.” “Yes. At first, we thought the Delta 32 mutation must have arisen during the Black Death in Europe—about four to sixteen percent of Europeans have at least one copy. But we’ve traced it back further. We thought perhaps smallpox, but we’ve found Bronze Age DNA samples that carry it. The mutation’s origins are a mystery, but one thing is certain: the bone marrow transplant with CCR5-Delta 32 cured both Brown’s leukemia and HIV. After the transplant, he stopped taking his antiretrovirals and has never again tested positive for HIV.
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A.G. Riddle (The Atlantis Plague (The Origin Mystery, #2))
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If you think about placing genetically tweaked stem cells from one human into another, having nothing go wrong is in itself remarkable. Since cell therapy is in its infancy, this was an important result.
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Rahul Jandial (Life Lessons From A Brain Surgeon: Practical Strategies for Peak Health and Performance)
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Neural stem cells are not the only type of living cell therapy being used to treat brain cancer. I’m part of the team developing a kind of anti-tumor immune therapy using what’s called chimeric antigen receptor (CAR)–engineered T-cells.
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Rahul Jandial (Life Lessons From A Brain Surgeon: Practical Strategies for Peak Health and Performance)
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Cancer is not the only brain disease being targeted for treatment with living cells. Cell therapy also has the potential to replace aging or injured tissue. In this hope for regenerative medicine, modified stem cells are being studied as a treatment for Alzheimer’s disease.
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Rahul Jandial (Life Lessons From A Brain Surgeon: Practical Strategies for Peak Health and Performance)
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Here Dr Sid Mirrafati has discussed about the essential advantages of stem cell and its importance which will provide the assist to increase the collagen and generate new heart & blood vessel tissue.
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Dr Sid Mirrafati
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A recent review summarizes the substantial evidence of their role in blood vessel formation and their therapeutic effect for many different conditions, particularly for cardiovascular diseases (ischemia, myocardial infarction, etc.), diabetes ulcers, burns, and wound healing.5
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Neil H. Riordan (Stem Cell Therapy: A Rising Tide: How Stem Cells Are Disrupting Medicine and Transforming Lives)
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Goodlife Physical Medicine now offering Stem cell regenerative injection therapy which will help our patients for accelerated healing time and pain control.
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Regenerative injection therapy
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The team at DFW Stem Cell Centers are experts in advanced stem cell therapy procedures. We've been serving the community for years and we strive to have the most cutting edge innovations available to our patients.
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DFW Stem Cell Centers
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Stem Cell Therapy for Liver Cirrhosis in Durban, Liver Cirrhosis treatment in South Africa
Stem Cell Therapy Is Emerging As An Alternative To Several Treatments In The Healthcare Industry.Stem Cell Therapy In South Africa Can Be Considered. The Doctors Also Suggest Liver Transplants Sometimes If Possible.Get In Touch With An Experienced Specialist That Offers Stem Cell Treatment In South Africa So That You Receive The Correct Guidance And Best Treatment.
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PT
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Terry Grossman, MD, regenerative medicine expert and author of multiple books on aging, including Transcend: Nine Steps to Living Well Forever, runs one of the few authorized stem cell therapy treatment centers in the United States.
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Sergey Young (The Science and Technology of Growing Young: An Insider's Guide to the Breakthroughs that Will Dramatically Extend Our Lifespan . . . and What You Can Do Right Now)
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STEP TWO: REVIEW YOUR EDUCATION If you’ve read this book, congratulations! You’ve given yourself a tremendous education. But knowledge isn’t power; it’s potential power. Decide what tools do you want to access today. And what do you want to keep track of in the future? 1. Are stem cells something that you want to pursue for some aspect of your life or for someone in your family? 2. Do you want to implement Dr. Sinclair’s Four Vitality Ingredients that help reverse biological aging? Or tap into the energy force of NMN? 3. Or, are there some technologies that you’ll want to keep track of so that you have them when you need them? Perhaps the Wnt Pathway for Osteoarthritis? 4. Is there anyone in your family or people you know whom you want to share information with about what you’ve learned here in the big 6—heart disease, diabetes/obesity, stroke, cancer, autoimmune disease, and Alzheimer’s? 5. Are you going to keep track of Gene Therapy and CRISPR and some of the transformations it’s creating? 6. Do you know anyone who has Parkinson’s or severe addiction who could feel relief from focused Ultrasound without brain surgery? Make a list of the things that you want to act on and things you want to keep track of, so that if you or anyone you know who needs help, you’ll have answers that you can share with them and that they can consider with their doctor. Just create a little checklist for yourself. The book is here. It’s the ultimate resource you can go back to as often as you need.
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Tony Robbins (Life Force: How New Breakthroughs in Precision Medicine Can Transform the Quality of Your Life & Those You Love)
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stem cell therapy in India | Best stem cell therapy centre in India
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stemcellcure1
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Stem cell treatment in India is becoming very famous lately the reason is the treatment methodology, skilled doctors, treatment cost and facilitation provided to the patients and their caretakers. The success rate of stem cell treatments have overall success rate ranging from 70% to 80% (depends on specific disease and patient’s condition) in India.
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Prashant
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In the years to come, some of our best minds will try to dig deeper into that computer program, to figure out its individual lines of code (the IF-THENS that we call genes), the products of those lines (what we call proteins), how all those lines of biological code fit together, and how they make room for nurture.
In the long run, the effects on society will be profound. Take, for example, the advances that our increasing understanding of genes will lead to in medicine. Because, as we have seen, the brain is built like the rest of the body, it is also amenable to many of the same types of treatment. For example, stem cell therapies originally developed for leukemia are being adapted to treat Parkinson's disease and Huntington's disease. Gene therapies developed for cystic fibrosis may someday help treat brain tumors. Both work by harnessing the body's own toolkit for development.
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Gary F. Marcus (The Birth of the Mind: How a Tiny Number of Genes Creates The Complexities of Human Thought)
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Terminology and classification Leukaemias are traditionally classified into four main groups: • acute lymphoblastic leukaemia (ALL) • acute myeloid leukaemia (AML) • chronic lymphocytic leukaemia (CLL) • chronic myeloid leukaemia (CML). In acute leukaemia there is proliferation of primitive stem cells leading to an accumulation of blasts, predominantly in the bone marrow, which causes bone marrow failure. In chronic leukaemia the malignant clone is able to differentiate, resulting in an accumulation of more mature cells. Lymphocytic and lymphoblastic cells are those derived from the lymphoid stem cell (B cells and T cells). Myeloid refers to the other lineages, i.e. precursors of red cells, granulocytes, monocytes and platelets (see Fig. 24.2, p. 989). The diagnosis of leukaemia is usually suspected from an abnormal blood count, often a raised white count, and is confirmed by examination of the bone marrow. This includes the morphology of the abnormal cells, analysis of cell surface markers (immunophenotyping), clone-specific chromosome abnormalities and molecular changes. These results are incorporated in the World Health Organization (WHO) classification of tumours of haematopoietic and lymphoid tissues; the subclassification of acute leukaemias is shown in Box 24.47. The features in the bone marrow not only provide an accurate diagnosis but also give valuable prognostic information, allowing therapy to be tailored to the patient’s disease.
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Nicki R. Colledge (Davidson's Principles and Practice of Medicine (MRCP Study Guides))
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The FDA will accept a certain level of risk for a new treatment that is to be applied to a group of very sick patients who would otherwise die in the near future, but not for a group who have a relatively long life expectancy on the basis of existing therapies.
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Jonathan M.W. Slack (Stem Cells: A Very Short Introduction (Very Short Introductions))
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Beware those who will try to hijack your hope to make a dollar (glutathione therapy, chelation, fee for stem cell treatment, miracle cures).
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Michael S. Okun (Parkinson's Treatment: 10 Secrets to a Happier Life)
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A stem cell treatment is an advanced medical innovation that helps repair and renew damaged nerves, muscles, cartilage, and other tissues. Stem cell therapy in India has been shown to work quickly and safely, and it works well.
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Prashant
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Despite the restriction of stem cells to just two regions of the mammalian central nervous system (CNS)—the lateral ventricle linings and the dentate gyrus—it is possible to grow neural stem cells in tissue culture from a much wider range of brain regions than this. The stem cells grow in a form called neurospheres. These are clumps of cells, up to 0.3 mm wide, that grow in suspension culture in a medium containing two specific growth factors (EGF and FGF). The cultures can be initiated from any part of the foetal CNS and often from parts of the adult CNS as well, even regions not thought to undergo continuous renewal. Neurospheres are thought each to contain a few neural stem cells, which are capable of self-renewal, plus a certain number of transit amplifying cells, that have finite division potential. When neurospheres are plated on an adhesive surface in the presence of serum, they will differentiate and form the three cell types normally generated by neuronal stem cells, which are neurons, and two types of glial cells: astrocytes and oligodendrocytes. If neurospheres are dissociated into single cells, a few per cent of these cells can establish new neurospheres, with similar properties to the original. Repeated cycles of dissociation and growth can provide substantial expansion capacity.
The phenomenon of neurospheres is an example of the fact that cells may behave in a different manner in tissue culture from in vivo. Neurospheres have created enormous interest because, unlike haematopoietic stem cells, they are expandable in vitro, and because there is a hope that they might be used for cell therapy of the very intractable neurodegenerative diseases involving widespread neuronal death.
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Jonathan M.W. Slack (Stem Cells: A Very Short Introduction)
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Haematopoietic stem cell transplantation is not a term that is immediately recognizable to the general public but it is actually the same as the much more familiar ‘bone marrow transplantation’. The rather long phrase haematopoietic stem cell transplantation (HSCT) is now preferred because it covers not just transplantation of bone marrow itself but other types of transplant where the blood-forming (haematopoietic) stem cells of the graft come from non-marrow sources such as peripheral blood or umbilical cord blood. Worldwide, about 50,000 HSCTs are carried out each year making this overwhelmingly the most important type of stem cell therapy in current practice. Most are done for treatment of cancer, mainly lymphomas and leukaemias, with about 5 per cent for treatment of non-malignant blood diseases and a few other conditions.
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Jonathan M.W. Slack (Stem Cells: A Very Short Introduction)
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There are also some potential safety concerns with grafts derived from pluripotent cells. Although Parkinson’s disease is a distressing condition that causes much suffering, it does not greatly reduce lifespan, so the period of time available for the development of complications is quite long, perhaps about 20 years on average. For any cell therapy derived from pluripotent stem cells there is always an issue about the possibility of persistence of a few pluripotent cells in the graft which might give rise to teratomas. Although the animal experiments indicate that the teratoma risk is very low, the long survival time of Parkinson’s patients does make even a very small cancer risk seem significant. Moreover, the differentiation protocols for pluripotent stem cells never produce 100 per cent of the desired cell type. Even if all the pluripotent cells are gone there will certainly be other types of neuron and glial cell present and these may generate unwanted effects. For example, the uncontrolled movement problems seen in some of the foetal midbrain graft recipients has been ascribed to the presence of other types of neuron which make inappropriate connections.
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Jonathan M.W. Slack (Stem Cells: A Very Short Introduction)
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Stem cells are the undifferentiated group of cells, they are unspecified and have a great potential for proliferation, differentiation and migration. Stem Cells are vital. They can rise specialized cells for body repair. Moreover, stem cell treatment has witnessed exceptional growth and development in past few years. Their consistency, self-repairing properties and profound healing response have led to the immense popularity of Stem Cell Therapy in South Africa.
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PT
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Three months after he received the cells, the boy’s father noticed his son’s eyes tracking a ball that his brother was bouncing. Suddenly the boy could see! There had been nothing wrong with his eyes. Instead, his blindness was caused by damage to his cerebral cortex. After several more treatments, the boy started to hear and talk, and could eventually walk with the aid of a walker. His parents were ecstatic. What I believe happened with our cultured cells is that they moved through the bloodstream to the damaged area, homing in on the site of the injury. Once there, the cells stimulated the formation of new blood vessels and secreted trophic factors, or bioactive molecules that encouraged new cell growth. Because the boy was so young and his system was so responsive, when blood started to flow to these areas, it jumpstarted his neural development and stimulated it to continue on a normal path, repairing some of the functions that had been damaged by his cerebral palsy.
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Neil H. Riordan (Stem Cell Therapy: A Rising Tide: How Stem Cells Are Disrupting Medicine and Transforming Lives)
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P2 - We are well on the way in a number of areas. Both billionaires and big Pharma are getting increasingly interested and money is starting to pour into research because it is clear we can see the light at the end of the tunnel which to investors equates to return on investment. Numerous factors will drive things forward and interest and awareness is increasing rapidly among both scientists, researchers and the general population as well as wealthy philanthropists. The greatest driving force of all is that the baby boomers are aging and this will place increasing demands on healthcare systems. Keep in mind that the average person costs more in medical expenditure in the last year of their life than all the other years put together. Also, the number of workers is declining in most developed countries which means that we need to keep the existing population working and productive as long as possible.
Below are a list which are basically all technologies potentially leading to radical life extension with number 5 highlighted which I assume might well be possible in the second half of the century:
1. Biotechnology - e.g stem cell therapies, enhanced autophagy, pharmaceuticals, immunotherapies, etc
2. Nanotechnology - Methods of repairing the body at a cellular and molecular level such as nanobots.
3. Robotics - This could lead to the replacement of increasing numbers of body parts and tends to go hand in hand with AI and whole brain emulation. It can be argued that this is not life extension and that it is a path toward becoming a Cyborg but I don’t share that view because even today we don’t view a quadriplegic as less human if he has four bionic limbs and this will hold true as our technology progresses.
4. Gene Therapies - These could be classified under the first category but I prefer to look at it separately as it could impact the function of the body in very dramatic ways which would suppress genes that negatively impact us and enhance genes which increase our tendency toward longer and healthier lives.
5. Whole brain emulation and mindscaping - This is in effect mind transfer to a non biological host although it could equally apply to uploading the brain to a new biological brain created via tissue engineering this has the drawback that if the original brain continues to exist the second brain would have a separate existence in other words whilst you are identical at the time of upload increasing divergence over time will be inevitable but it means the consciousness could never die provided it is appropriately backed up.
So what is the chance of success with any of these? My answer is that in order for us to fail to achieve radical life extension by the middle of the century requires that all of the above technologies must also fail to progress which simply won't happen and considering the current rate of development which is accelerating exponentially and then factoring in that only one or two of the above are needed to achieve life extension (although the end results would differ greatly) frankly I can’t see how we can fail to make enough progress within 10-20 years to add at least 20 to 30 years to current life expectancy from which point progress will rapidly accelerate due to increased funding turning aging at the very least into a manageable albeit a chronic incurable condition until the turn of the 22nd century. We must also factor in that there is also a possibility that we could find a faster route if a few more technologies like CRISPR were to be developed. Were that to happen things could move forward very rapidly.
In the short term I'm confident that we will achieve significant positive results within a year or two in research on mice and that the knowledge acquired will then be transferred to humans within around a decade.
According to ADG, a dystopian version of the post-aging world like in the film 'In Time' not plausible in the real world: "If you CAREFULLY watch just the first
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Aubrey de Grey
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Get in touch with us to avail the best stem cell treatment in India. Stem Cell Cure Pvt Ltd is a leading healthcare industry providing stem cells therapy for all degenerative disease
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stemcellcure1
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Metro Denver Regenerative Medicine is an advanced pain management clinic using the latest therapies available. Our pain treatments include using the patient's own tissues such as PRP, bone marrow and adipose tissues as well as other stem cell therapies and injections.
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Metro Denver Regenerative Medicine