Pro Immunization Quotes

So many modern diseases, including heart disease, depression, cancer, Alzheimer’s, and all the autoimmune diseases (such as rheumatoid arthritis and lupus), occur in part because our body’s immune systems produce excess chronic inflammation. In chronic inflammation, the immune system stays on too long and may even begin to attack the body’s own tissues, as though they were outside invaders. The causes of chronic inflammation are many, including diet and, of course, the countless chemical toxins that become embedded in the body. Chronically inflamed bodies produce chemicals, called pro-inflammatory cytokines, which contribute to pain and inflammation.

Perhaps there is something within the genetic make-up of specific individuals which predisposes them to accumulate and retain aluminium in their brain, as is similarly suggested for individuals with familial Alzheimer’s disease. The new evidence strongly suggests that aluminium is entering the brain in ASD via pro-inflammatory cells which have become loaded up with aluminium in the blood and/or lymph, much as has been demonstrated for monocytes at injection sites for vaccines including aluminium adjuvants. Perhaps we now have the putative link between vaccination and ASD, the link being the inclusion of an aluminium adjuvant in the vaccine.

He had negotiated an immunity agreement for himself that protected him from future prosecution in exchange for his cooperation and testimony. In effect a legal quid pro quo—the same theory the government used in its indictment of me with charges of extortion and bribery. I will never understand why when a citizen allegedly does it, it’s illegal and when the government does it, it’s legal.

Vitamin D3 boasts a strong safety profile, along with broad and deep evidence that links it to brain, metabolic, cardiovascular, muscle, bone, lung, and immune health. New and emerging research suggests that vitamin D supplements may also slow down our epigenetic/biological aging.29, 30 2. Omega-3 fish oil: Over the last thirty years or so, the typical Western diet has added more and more pro-inflammatory omega-6 polyunsaturated fatty acids versus anti-inflammatory omega-3 PUFAs. Over the same period, we’ve seen an associated rise in chronic inflammatory diseases, including obesity, cardiovascular disease, rheumatoid arthritis, and Alzheimer’s disease. 31 Rich in omega-3s, fish oil is another incredibly versatile nutraceutical tool with multi-pronged benefits from head to toe. By restoring a healthier PUFA ratio, it especially helps your brain and heart. Regular consumption of fatty fish like salmon has been linked to a lower risk of congestive heart failure, coronary heart disease, sudden cardiac death, and stroke.32 In an observational study, omega-3 fish oil supplementation was also associated with a slower biological clock.33 3. Magnesium deficiency affects more than 45 percent of the U.S. population. Supplements can help us maintain brain and cardiovascular health, normal blood pressure, and healthy blood sugar metabolism. They may also reduce inflammation and help activate our vitamin D. 4. Vitamin K1/K2 supports blood clotting, heart/ blood vessel health, and bone health.34 5. Choline supplements with brain bioavailability, such as CDP-Choline, citicoline, or alpha-GPC, can boost your body’s storehouse of the neurotransmitter acetylcholine and possibly support liver and brain function, while protecting it from age-related insults.35 6. Creatine: This one may surprise you, since it’s often associated with serious athletes and fitness buffs. But according to Dr. Lopez, it’s “a bona fide arrow in my longevity nutraceutical quiver for most individuals, and especially older adults.” As a coauthor of a 2017 paper by the International Society for Sports Nutrition, Dr. Lopez, along with contributors, stated that creatine not only enhances recovery, muscle mass, and strength in connection with exercise, but also protects against age-related muscle loss and various forms of brain injury.36 There’s even some evidence that creatine may boost our immune function and fat and carbohydrate metabolism. Generally well tolerated, creatine has a strong safety profile at a daily dose of three to five grams.37 7.

In a randomized controlled trial, study subjects who substituted whole grains for refined grains saw growth of SCFA-producing bacteria Lachnospira, increased SCFA levels, and a decrease in pro-inflammatory Enterobacteriaceae. They also noted improvement in the immune system and no effect on gut inflammation.

Generous, pro-social behavior seems to strengthen these relationships across cultures. Generosity is even associated with better health and longer life expectancy. Generosity seems to be so powerful that, according to researchers David McClelland and Carol Kirshnit, just thinking about it “significantly increases the protective antibody salivary immunoglobulin A, a protein used by the immune system.

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Humans have natural rights in the state of nature but they do not have civil rights. Civil rights are derived from membership in a society. The Republicans who controlled both houses of Congress after the Civil War knew this. They also knew that, before conferring civil rights, they had to once and for all abolish slavery. The Thirteenth Amendment ending slavery was passed by the Senate on April 8, 1864, and by the House on January 31, 1865. Republican support for the amendment: 100 percent. Democratic support: 23 percent. Even after the Civil War, only a tiny percentage of Democrats were willing to sign up to permanently end slavery. Most Democrats wanted it to continue. In the following year, on June 13, 1866, the Republican Congress passed the Fourteenth Amendment overturning the Dred Scott decision and granting full citizenship and equal rights under the law to blacks. This amendment prohibited states from abridging the “privileges and immunities” of all citizens, from depriving them of “due process of law” or denying them “equal protection of the law.” The Fourteenth Amendment passed the House and Senate with exclusive Republican support. Not a single Democrat either in the House or the Senate voted for it. Two years later, in 1868, Congress with the support of newly-elected Republican president Ulysses Grant passed the Fifteenth Amendment granting suffrage to blacks. The right to vote, it said, cannot be “denied or abridged by the United States or any state on account of race, color or previous condition of servitude.” In the Senate, the Fifteenth Amendment passed by a vote of 39 to 13. Every one of the 39 “yes” votes came from Republicans. (Some Republicans like Charles Sumner abstained because they wanted the measure to go even further than it did.) All the 13 “no” votes came from Democrats. In the House, every “yes” vote came from a Republican and every Democrat voted “no.” It is surely a matter of the greatest significance that the constitutional provisions that made possible the Civil Rights Act, the Voting Rights Act, and the Fair Housing Bill only entered the Constitution thanks to the Republican Party. Beyond this, the GOP put forward a series of Civil Rights laws to further reinforce black people’s rights to freedom, equality, and social justice. When Republicans passed the Civil Rights Act of 1866—guaranteeing to blacks the rights to make contracts and to have the criminal laws apply equally to whites and blacks—the Democrats struck back. They didn’t have the votes in Congress, but they had a powerful ally in President Andrew Johnson. Johnson vetoed the legislation. Now this may seem like an odd act for Lincoln’s vice president, but it actually wasn’t. Many people don’t realize that Johnson wasn’t a Republican; he was a Democrat. Historian Kenneth Stampp calls him “the last Jacksonian.”8 Lincoln put him on the ticket because he was a pro-union Democrat and Lincoln was looking for ways to win the votes of Democrats opposed to secession. Johnson, however, was both a southern partisan and a Democratic partisan. Once the Civil War ended, he attempted to lead weak-kneed Republicans into a new Democratic coalition based on racism and white privilege. Johnson championed the Democratic mantra of white supremacy, declaring, “This is a country for white men and, by God, as long as I am president, it shall be a government of white men.” In his 1867 annual message to Congress, Johnson declared that blacks possess “less capacity for government than any other race of people. No independent government of any form has ever been successful in their hands. On the contrary, wherever they have been left to their own devices they have shown a consistent tendency to relapse into barbarism.”9 These are perhaps the most racist words uttered by an American president, and no surprise, they were uttered by a Democrat.

Last, and perhaps most important, prolonged sitting can kindle chronic inflammation by allowing muscles to remain persistently inactive. In addition to moving our bodies, muscles function as glands, synthesizing and releasing dozens of messenger proteins (termed myokines) with important roles. Among other jobs, myokines influence metabolism, circulation, and bones, and—you guessed it—they also help control inflammation. In fact, when researchers first started to study myokines, they were astonished to discover that muscles regulate inflammation during bouts of moderate to intense physical activity similarly to the way the immune system mounts an inflammatory response to an infection or a wound.40 Without going into too many details, we have learned that the body first initiates a proactive inflammatory response to moderate- or high-intensity physical activity to prevent or repair damage caused by the physiological stress of exercise and subsequently activates a second, larger anti-inflammatory response to return us to a non-inflamed state.41 Because the anti-inflammatory effects of physical activity are almost always larger and longer than the pro-inflammatory effects, and muscles make up about a third of the body, active muscles have potent anti-inflammatory effects. Even modest levels of physical activity dampen levels of chronic inflammation, including in obese people.42

At the beginning of the twenty-first century, physicians such as Iain McInnes were finding out that new biologic drugs designed for inflammatory conditions like rheumatoid arthritis could treat symptoms of depression. A number of researchers have since trawled back through the results of clinical trials that tested anti-inflammatory drugs for various chronic inflammatory conditions such as rheumatoid arthritis, lupus, psoriasis, asthma and inflammatory bowel disease. They were particularly interested in trials that also reported data for symptoms of depression as a secondary outcome. The overwhelming picture is that anti-inflammatory drugs – from older, generalized drugs such as ibuprofen and aspirin to new, targeted monoclonal antibodies – tend to improve depressive symptoms.22 One study, carried out in 2020, was able to look at very detailed patient data from eighteen clinical trials and factored in patients’ physical improvements. These trials had used a range of new anti-inflammatory drugs designed to target the inflammation behind various autoimmune diseases. Two drugs in particular demonstrated an improvement in low mood, regardless of improvement in physical symptoms. These were both antibody drugs that specifically targeted pro-inflammatory cytokines: sirukumab relieves rheumatoid arthritis by targeting IL-6, and ustekinumab treats psoriasis by blocking the cytokines for IL-12 and IL-23. Here we have data to back up Iain McInnes’s observations in his arthritis clinic: anti-inflammatory medication treating the psychological symptoms of depression, regardless of the state of physical symptoms. This doesn’t just help to strengthen an argument for inflammation causing some forms of depression; it offers hope of a treatment.

The results of the first clinical trial of one of the new generation of anti-inflammatory drugs were published in 2013. Eminent American academic psychiatrists Charles Raison and Andrew Miller led a study at Emory University in Atlanta, Georgia, in which patients with depression were given either a drug called infliximab or a placebo.25 Infliximab is a biologic drug that targets the pro-inflammatory cytokine TNF-α and is used in a number of autoimmune conditions. But the results were disappointing: no difference in depression-score reduction between infliximab and the placebo. But when they analysed the data further, they saw that a subgroup of patients did respond well to the medication: those who tended to have a mildly raised background level of inflammatory markers. Specifically, these were patients who had a raised baseline level of C-reactive protein (CRP) – a generic marker of inflammation in the body. A later, larger study assessed the anti-IL-6 drug sirukumab on patients who had not responded to conventional antidepressants and who had raised baseline levels of CRP.26 In this group, the drug improved only the depressive symptom of anhedonia (inability to experience pleasure), though in patients with a very high background CRP, it helped relieve depression better than the placebo.

Alcohol destroys our health by attacking our liver and immune system and is related to more than sixty diseases.53 Yet because we are only peripherally aware of the harms but very familiar with pro-alcohol social messages, we often justify our drinking by saying we drink for the taste. And we believe this is true. We have an uncanny ability to unknowingly deceive ourselves.

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