Physiology Related Quotes

Gross well says that children are young because they play, and not vice versa; and he might have added, men grow old because they stop playing, and not conversely, for play is, at bottom, growth, and at the top of the intellectual scale it is the eternal type of research from sheer love of truth.

Complexly traumatized children need to be helped to engage their attention in pursuits that do not remind them of trauma-related triggers and that give them a sense of pleasure and mastery. Safety, predictability, and "fun" are essential for the establishment of the capacity to observe what is going on, put it into a larger context, and initiate physiological and motoric self-regulation.

Everything in physiology follows the rule that too much can be as bad as too little. There are optimal points of allostatic balance. For example, while a moderate amount of exercise generally increases bone mass, thirty-year-old athletes who run 40 to 50 miles a week can wind up with decalcified bones, decreased bone mass, increased risk of stress fractures and scoliosis (sideways curvature of the spine)—their skeletons look like those of seventy-year-olds. To put exercise in perspective, imagine this: sit with a group of hunter-gatherers from the African grasslands and explain to them that in our world we have so much food and so much free time that some of us run 26 miles in a day, simply for the sheer pleasure of it. They are likely to say, “Are you crazy? That’s stressful.” Throughout hominid history, if you’re running 26 miles in a day, you’re either very intent on eating someone or someone’s very intent on eating you.

The dissociation between fear and aggression is evident in violent psychopaths, who are the antithesis of fearful—both physiologically and subjectively they are less reactive to pain; their amygdalae are relatively unresponsive to typical fear-evoking stimuli and are smaller than normal.34 This fits with the picture of psychopathic violence; it is not done in aroused reaction to provocation. Instead, it is purely instrumental, using others as a means to an end with emotionless, remorseless, reptilian indifference.

Humans are built to move. We evolved under conditions that required daily intense physical activity, and even among individuals with lower physical potential, that hard-earned genotype is still ours today. The modern sedentary lifestyle leads to the inactivation of the genes related to physical performance, attributes that were once critical for survival and which are still critical for the correct, healthy expression of the genotype. The genes are still there, they just aren't doing anything because the body is not stressed enough to cause a physiological adaptation requiring their activation. The sedentary person's heart, lungs, muscles, bones, nerves and brain all operate far below the level at which they evolved to function, and at which they still function best.

This is the critical point of this book: if you are that zebra running for your life, or that lion sprinting for your meal, your body’s physiological response mechanisms are superbly adapted for dealing with such short-term physical emergencies. For the vast majority of beasts on this planet, stress is about a short-term crisis, after which it’s either over with or you’re over with. When we sit around and worry about stressful things, we turn on the same physiological responses—but they are potentially a disaster when provoked chronically. A large body of evidence suggests that stress-related disease emerges, predominantly, out of the fact that we so often activate a physiological system that has evolved for responding to acute physical emergencies, but we turn it on for months on end, worrying about mortgages, relationships, and promotions.

The fate of the physiology of the brain is independent of the truth and falsity of my assertions relative to the laws of the organization of the nervous system, in general, and of the brain in particular, just as the knowledge of the functions of a sense is independent of the knowledge of the structure of its apparatus.

I know that certain minds would regard as audacious the idea of relating the laws which preside over the play of our organs to those laws which govern inanimate bodies; but, although novel, this truth is none the less incontestable. To hold that the phenomena of life are entirely distinct from the general phenomena of nature is to commit a grave error, it is to oppose the continued progress of science.

God is thus entrenched in the Flow systems as a causal belief, but an unordered one. Within Flow, this is implemented as unordered in relation with the ordered. The responsibility of first Cause and causes as effects including physiological causes are passed on to God. In fact, to devout Christians, God is all causation incessantly.

As graduation loomed, I had a nagging sense that there was still far too much unresolved for me, that I wasn’t done studying. I applied for a master’s in English literature at Stanford and was accepted into the program. I had come to see language as an almost supernatural force, existing between people, bringing our brains, shielded in centimeter-thick skulls, into communion. A word meant something only between people, and life’s meaning, its virtue, had something to do with the depth of the relationships we form. It was the relational aspect of humans—i.e., “human relationality”—that undergirded meaning. Yet somehow, this process existed in brains and bodies, subject to their own physiologic imperatives, prone to breaking and failing. There must be a way, I thought, that the language of life as experienced—of passion, of hunger, of love—bore some relationship, however convoluted, to the language of neurons, digestive tracts, and heartbeats.

If you turn to a branch of those sciences that try to give a solution to the questions of life--to physiology, psychology, biology, sociology--there you will find an astounding poverty of thought, a very great lack of clarity, completely unjustified claims to answer questions that lie outside their subject and never-ending contradictions between one thinker and others, and even within himself. If you turn to a branch of the sciences that is not concerned with solving the questions of life but answers its own scientific, specialized questions, then you are captivated by the power of human intellect but you know in advance that there are no answers to the questions of life. These sciences directly ignore the questions of life. They say, "We have no answers to 'What are you?' and 'Why do you live?' and are not concerned with this; but if you need to know the laws of light, of chemical compounds, the laws of the development of organisms, if you need to know the laws of bodies and their forms and the relation of numbers and quantities, if you need to know the laws of your own mind, to all that we have clear, precise, and unquestionable answers.

I had come to see language as an almost supernatural force, existing between people, bringing our brains, shielded in centimeter-thick skulls, into communion. A word meant something only between people, and life’s meaning, its virtue, had something to do with the depth of the relationships we form. It was the relational aspect of humans — i.e., “human relationality” — that undergirded meaning. Yet somehow, this process existed in brains and bodies, subject to their own physiologic imperatives, prone to breaking and failing. There must be a way, I thought, that the language of life as experienced — of passion, of hunger, of love — bore some relationship, however convoluted, to the language of neurons, digestive tracts, and heartbeats.

…I felt nothing. I could think of feelings, emotions, but I couldn't bring them up in me. I couldn't even locate where my emotions came from. My brain? It made no sense. Irritation was what I knew best—a heaviness on my chest, a vibration in my neck like my head was revving up before it would rocket off my body. But that seemed directly tied to my nervous system—a physiological response. Was sadness the same kind of thing? Was joy? Was longing? Was love?

For the correct Marxist classification of the proletariat-the class which is forced by socio-economic compulsion to sell its labour-power to the capitalist owners of the means of production – implies that both variations in the level of the reserve army of labour, and the variegated relations between the ‘purely physiological’ and ‘moral-historical’ components of the value of labour-power,63 are of decisive importance for the proletarian’s immediate destiny.

Many survivors of relational and other forms of early life trauma are deeply troubled and often struggle with feelings of anger, grief, alienation, distrust, confusion, low self-esteem, loneliness, shame, and self-loathing. They seem to be prisoners of their emotions, alternating between being flooded by intense emotional and physiological distress related to the trauma or its consequences and being detached and unable to express or feel any emotion at all - alternations that are the signature posttraumatic pattern. These occur alongside or in conjunction with other common reactions and symptoms (e.g., depression, anxiety, and low self-esteem) and their secondary manifestations. Those with complex trauma histories often have diffuse identity issues and feel like outsiders, different from other people, whom they somehow can't seem to get along with, fit in with, or get close to, even when they try. Moreover, they often feel a sense of personal contamination and that no one understands or can help them. Quite frequently and unfortunately, both they and other people (including the professionals they turn to for help) do misunderstand them, devalue their strengths, or view their survival adaptations through a lens of pathology (e.g., seeing them as "demanding", "overdependent and needy", "aggressive", or as having borderline personality). Yet, despite all, many individuals with these histories display a remarkable capacity for resilience, a sense of morality and empathy for others, spirituality, and perseverance that are highly admirable under the circumstances and that create a strong capacity for survival. Three broad categories of survivorship, with much overlap between them, can be discerned: 1. Those who have successfully overcome their past and whose lives are healthy and satisfying. Often, individuals in this group have had reparative experiences within relationships that helped them to cope successfully. 2. Those whose lives are interrupted by recurring posttraumatic reactions (often in response to life events and experiences) that periodically hijack them and their functioning for various periods of time. 3. Those whose lives are impaired on an ongoing basis and who live in a condition of posttraumatic decline, even to the point of death, due to compromised medical and mental health status or as victims of suicide of community violence, including homicide.

Attachment is central to the context in which all other action systems mature. If attachment is disrupted early in life, it may lead to maladaptive functioning in various areas of life because the most basic action systems do not function well. Attachment relationships assist individuals in regulating their emotions and physiology, providing basic internal and relational stability.

Discovery is thus inextricably interwoven with what is known as error. To recognize a certain relation, many another relation must be misunderstood, denied, or overlooked. The operation of cognition [Erkenntnisphysiologie] is analogous to the physiology of movement. To move a limb, an entire so-called myostatic system must be immobilized to provide a basis of fixation. Every movement consists of two active processes; namely, motion and inhibition. The corresponding features in the operation of cognition are purposive, directed determination and cooperative abstraction, which complement one another.

Recovery requires an environment of relative security and the ability to separate the physiology of freeze from the experience of fear, so that the panic and the rage can discharge, completing their cycles at last.

Most people didn't even think aliens really existed. And among those who did believe, "my" relatives had a bad rep. Little, gray and creepy. Known for cattle mutilations, abductions, and an extreme fascination with probing of all kinds. Not that any of those rumors were true, as far as I knew. Exept for the being little and gray-that bit was accurate, as far as I could tell, based on my own physiology and the Internet, of course.

We face no such difficulty if we see that what is being transmitted genetically is not ADD or its equally ill-mannered and discombobulating relatives, but sensitivity. The existence of sensitive people is an advantage for humankind because it is this group that best expresses humanity’s creative urges and needs. Through their instinctual responses the world is best interpreted. Under normal circumstances, they are artists or artisans, seekers, inventors, shamans, poets, prophets. There would be valid and powerful evolutionary reasons for the survival of genetic material coding for sensitivity. It is not diseases that are being inherited but a trait of intrinsic survival value to human beings. Sensitivity is transmuted into suffering and disorders only when the world is unable to heed the exquisitely tuned physiological and psychic responses of the sensitive individual.

Environmental influences also affect dopamine. From animal studies, we know that social stimulation is necessary for the growth of the nerve endings that release dopamine and for the growth of receptors that dopamine needs to bind to in order to do its work. In four-month-old monkeys, major alterations of dopamine and other neurotransmitter systems were found after only six days of separation from their mothers. “In these experiments,” writes Steven Dubovsky, Professor of Psychiatry and Medicine at the University of Colorado, “loss of an important attachment appears to lead to less of an important neurotransmitter in the brain. Once these circuits stop functioning normally, it becomes more and more difficult to activate the mind.” A neuroscientific study published in 1998 showed that adult rats whose mothers had given them more licking, grooming and other physical-emotional contact during infancy had more efficient brain circuitry for reducing anxiety, as well as more receptors on nerve cells for the brain’s own natural tranquilizing chemicals. In other words, early interactions with the mother shaped the adult rat’s neurophysiological capacity to respond to stress. In another study, newborn animals reared in isolation had reduced dopamine activity in their prefrontal cortex — but not in other areas of the brain. That is, emotional stress particularly affects the chemistry of the prefrontal cortex, the center for selective attention, motivation and self-regulation. Given the relative complexity of human emotional interactions, the influence of the infant-parent relationship on human neurochemistry is bound to be even stronger. In the human infant, the growth of dopamine-rich nerve terminals and the development of dopamine receptors is stimulated by chemicals released in the brain during the experience of joy, the ecstatic joy that comes from the perfectly attuned mother-child mutual gaze interaction. Happy interactions between mother and infant generate motivation and arousal by activating cells in the midbrain that release endorphins, thereby inducing in the infant a joyful, exhilarated state. They also trigger the release of dopamine. Both endorphins and dopamine promote the development of new connections in the prefrontal cortex. Dopamine released from the midbrain also triggers the growth of nerve cells and blood vessels in the right prefrontal cortex and promotes the growth of dopamine receptors. A relative scarcity of such receptors and blood supply is thought to be one of the major physiological dimensions of ADD. The letters ADD may equally well stand for Attunement Deficit Disorder.

This is great. But what I’m grasping at is an idea about a subtler goal. This thinking owes a lot to conversations with Manjula Waldron of Ohio State University, an engineering professor who also happens to be a hospital chaplain. This feels embarrassingly Zen-ish for me to spout, being a short, hypomanic guy with a Brooklyn accent, but here goes: Maybe the goal isn’t to maximize the contrast between a low baseline and a high level of activation. Maybe the idea is to have both simultaneously. Huh? Maybe the goal would be for your baseline to be something more than the mere absence of activation, a mere default, but to instead be an energized calm, a proactive choice. And for the ceiling to consist of some sort of equilibrium and equanimity threading through the crazed arousal. I have felt this a few times playing soccer, inept as I am at it, where there’s a moment when, successful outcome or not, every physiological system is going like mad, and my body does something that my mind didn’t even dream of, and the two seconds when that happened seemed to take a lot longer than it should have. But this business about the calm amid the arousal isn’t just another way of talking about “good stress” (a stimulating challenge, as opposed to a threat). Even when the stressor is bad and your heart is racing in crisis, the goal should be to somehow make the fraction of a second between each heartbeat into an instant that expands in time and allows you to regroup. There, I have no idea what I’m talking about, but I think there might be something important lurking there. Enough said.

Underneath your sexuality is the drive and desire to be known and loved. God created you as a sexual being so that you might understand what it means to long, to desire, and to crave intimate oneness. Your sexuality was never meant to be an isolated physiological urge that is expressed apart from the rest of who you are as a woman. You have longings to share your heart, soul, and body with another person because God made you a deeply relational and spiritual woman. Your greatest need for intimacy however is to know the god who created you.

The price of freedom is eternal mindfulness. This is a book about restoring connection. It is the experience of being in connection that fulfills the longing we have to feel fully alive. An impaired capacity for connection to self and others, and the ensuing diminished aliveness, are the hidden dimensions that underlie most psychological and many physiological problems. Unfortunately, we are often unaware of the internal roadblocks that keep us from experiencing the connection and aliveness we yearn for. These roadblocks develop in reaction to developmental and shock trauma and the related nervous system dysregulation, disruptions in attachment, and distortions of identity. The goal of the NeuroAffective Relational Model (NARM) is to work with these dysregulations, disruptions, and distortions while never losing sight of supporting the development of a healthy capacity for connection and aliveness. In this book we address conflicts around the capacity for connection and explore how deeper connection and aliveness can be supported in the process of healing developmental trauma.

The abyss that divides the two modalities of experience — sacred and profane — will be apparent when we come to describe sacred space and the ritual building of the human habitation, or the varieties of the religious experience of time, or the relations of religious man to nature and the world of tools, or the consecration of human life itself, the sacrality with which man’s vital functions (food, sex, work and so on) can be charged. Simply calling to mind what the city or the house, nature, tools, or work have become for modern and nonreligious man will show with the utmost vividness all that distinguishes such a man from a man belonging to any archaic society, or even form a peasant of Christian Europe. For modern consciousness, a physiological act — eating, sex, and so on — is in sum only an organic phenomenon, however much it may still be encumbered by tabus (imposing, for example, particular rules for "eating properly" or forbidding some sexual behavior disapproved by social morality). But for the primitive, such an act is never simply physiological; it is , or can become, a sacrament, that is, a communion with the sacred.

A word meant something only between people, and life’s meaning, its virtue, had something to do with the depth of the relationships we form. It was the relational aspect of humans—i.e., “human relationality”—that undergirded meaning. Yet somehow, this process existed in brains and bodies, subject to their own physiologic imperatives, prone to breaking and failing. There must be a way, I thought, that the language of life as experienced—of passion, of hunger, of love—bore some relationship, however convoluted, to the language of neurons, digestive tracts, and heartbeats.

A critical realization roared through the research community: the physiological stress-response can be modulated by psychological factors. Two identical stressors with the same extent of allostatic disruption can be perceived, can be appraised differently, and the whole show changes from there.

For the vast majority of beasts on this planet, stress is about a short-term crisis, after which it’s either over with or you’re over with. When we sit around and worry about stressful things, we turn on the same physiological responses—but they are potentially a disaster when provoked chronically

A large body of evidence suggests that stress-related disease emerges, predominantly, out of the fact that we so often activate a physiological system that has evolved for responding to acute physical emergencies, but we turn it on for months on end, worrying about mortgages, relationships, and promotions.

A word meant something only between people, and life's meaning, its virtue, had something to do with the depth of the relationships we form. It was the relational aspect of humans that undergirded meaning. Yet somehow, this process existed in brains and bodies, subject to their own physiologic imperatives, prone to breaking and failing.

when we get into a physiological uproar and activate the stress-response for no reason at all, or over something we cannot do anything about, we call it things like “anxiety,” “neurosis,” “paranoia,” or “needless hostility.” Thus, the stress-response can be mobilized not only in response to physical or psychological insults, but also in expectation of them.

CONSENSUS PROPOSED CRITERIA FOR DEVELOPMENTAL TRAUMA DISORDER A. Exposure. The child or adolescent has experienced or witnessed multiple or prolonged adverse events over a period of at least one year beginning in childhood or early adolescence, including: A. 1. Direct experience or witnessing of repeated and severe episodes of interpersonal violence; and A. 2. Significant disruptions of protective caregiving as the result of repeated changes in primary caregiver; repeated separation from the primary caregiver; or exposure to severe and persistent emotional abuse B. Affective and Physiological Dysregulation. The child exhibits impaired normative developmental competencies related to arousal regulation, including at least two of the following: B. 1. Inability to modulate, tolerate, or recover from extreme affect states (e.g., fear, anger, shame), including prolonged and extreme tantrums, or immobilization B. 2. Disturbances in regulation in bodily functions (e.g. persistent disturbances in sleeping, eating, and elimination; over-reactivity or under-reactivity to touch and sounds; disorganization during routine transitions) B. 3. Diminished awareness/dissociation of sensations, emotions and bodily states B. 4. Impaired capacity to describe emotions or bodily states C. Attentional and Behavioral Dysregulation: The child exhibits impaired normative developmental competencies related to sustained attention, learning, or coping with stress, including at least three of the following: C. 1. Preoccupation with threat, or impaired capacity to perceive threat, including misreading of safety and danger cues C. 2. Impaired capacity for self-protection, including extreme risk-taking or thrill-seeking C. 3. Maladaptive attempts at self-soothing (e.g., rocking and other rhythmical movements, compulsive masturbation) C. 4. Habitual (intentional or automatic) or reactive self-harm C. 5. Inability to initiate or sustain goal-directed behavior D. Self and Relational Dysregulation. The child exhibits impaired normative developmental competencies in their sense of personal identity and involvement in relationships, including at least three of the following: D. 1. Intense preoccupation with safety of the caregiver or other loved ones (including precocious caregiving) or difficulty tolerating reunion with them after separation D. 2. Persistent negative sense of self, including self-loathing, helplessness, worthlessness, ineffectiveness, or defectiveness D. 3. Extreme and persistent distrust, defiance or lack of reciprocal behavior in close relationships with adults or peers D. 4. Reactive physical or verbal aggression toward peers, caregivers, or other adults D. 5. Inappropriate (excessive or promiscuous) attempts to get intimate contact (including but not limited to sexual or physical intimacy) or excessive reliance on peers or adults for safety and reassurance D. 6. Impaired capacity to regulate empathic arousal as evidenced by lack of empathy for, or intolerance of, expressions of distress of others, or excessive responsiveness to the distress of others E. Posttraumatic Spectrum Symptoms. The child exhibits at least one symptom in at least two of the three PTSD symptom clusters B, C, & D. F. Duration of disturbance (symptoms in DTD Criteria B, C, D, and E) at least 6 months. G. Functional Impairment. The disturbance causes clinically significant distress or impairment in at least two of the following areas of functioning: Scholastic Familial Peer Group Legal Health Vocational (for youth involved in, seeking or referred for employment, volunteer work or job training)

A word meant something only between people, and life’s meaning, its virtue, had something to do with the depth of the relationships we form. It was the relational aspect of humans—i.e., “human relationality”—that undergirded meaning. Yet somehow, this process existed in brains and bodies, subject to their own physiologic imperatives, prone to breaking and failing

What is knowledge? it is primarily and essentially idea. What is idea? A very complicated physiological process in the brain of an animal, the result of which is the consciousness of a picture there. Clearly the relation between such a picture and something entirely different from the animal in whose brain it exists can only be a very indirect one. This is perhaps the simplest and most comprehensible way of disclosing the deep gulf between the ideal and the real. This belongs to the things of which, like the motion of the earth, we are not directly conscious; therefore the ancients did not observe it, just as they did not observe the motion of the earth. Once pointed out, on the other hand, first by Descartes, it has ever since given philosophers no rest. But after Kant had at last proved in the most thorough manner the complete diversity of the ideal and the real, it was an attempt, as bold as it was absurd, yet perfectly correctly calculated with reference to the philosophical public in Germany, and consequently crowned with brilliant results, to try to assert the absolute identity of the two by dogmatic utterances, on the strength of a pretended intellectual intuition. In truth, on the contrary, a subjective and an objective existence, a being for self and a being for others, a consciousness of one's own self, and a consciousness of other things, is given us directly, and the two are given in such a fundamentally different manner that no other difference can compare with this. About himself every one knows directly, about all others only very indirectly. This is the fact and the problem.

You must control bugs,” I say. “Bugs no eat fruit,” it answers. In other words, how can you control an animal except with fruit? “Change sap for bugs. Like this.” I show a chemical. “Sap will control animals.” “Bugs no eat fruit.” “Bugs drink sap.” “Yes,” it says. “Bugs no eat fruit.” “Change sap for bugs because bugs drink sap, no eat fruit.” “Bugs no eat fruit.” I realize that we are related plants, both bamboos, in fact, and our shared physiology is the only reason I can have a conversation of any complexity. The hedge along the river is too small to have many sentient roots. The presence of other snow vines triggers an aggressive growth, but this hedge has lived alone and is content to lead a manicured little life parasitizing its aspens and putting down more guard roots than it needs, thus serving the humans without realizing it. It has no need for intelligence, none at all. “Change sap for bugs,” I repeat, hoping that repetition will of itself prove persuasive. “Big animals eat bugs.” “Bugs no eat fruit.” “Big animals eat bugs.” “Big animals eat bugs,” the snow vine repeats. I have made progress. “Yes,” I say. “Change sap for bugs.” “Big animals eat bugs.” “Yes. Change sap for bugs. Like this.” “Bugs eat sap,” it says. “Bugs are pests.” “Bugs are good. Big animals eat bugs like fruit.” The snow vine stammers some meaningless chemical compounds and finally says, “Bugs are like fruit.” This is very significant progress. “Bugs are like fruit,” I agree. “Bugs eat sap. Change sap. Sap will control two animals.” “Sap will control bugs. Big animals eat bugs.” “Yes. You must change sap for bugs and animals.” “I will change sap for bugs and animals.” At last! “Yes. Change sap like this.” I deliver some prototype chemicals.

The British anthropologist Robin Dunbar represents one exception to the otherwise typical neglect of intoxication. Dunbar and his colleagues see the physiological effects of alcohol, in particular, as a crucial component in social rituals. Specifically, they point to the endorphin release triggered by booze, especially when drinking is combined with music, dance, and ritual, as a crucial factor allowing humans to cooperate on a scale unattainable by our monkey or ape relatives.

You’ve heard the expression “total war”; it’s pretty common throughout human history. Every generation or so, some gasbag likes to spout about how his people have declared “total war” against an enemy, meaning that every man, woman, and child within his nation was committing every second of their lives to victory. That is bullshit on two basic levels. First of all, no country or group is ever 100 percent committed to war; it’s just not physically possible. You can have a high percentage, so many people working so hard for so long, but all of the people, all of the time? What about the malingerers, or the conscientious objectors? What about the sick, the injured, the very old, the very young? What about when you’re sleeping, eating, taking a shower, or taking a dump? Is that a “dump for victory”? That’s the first reason total war is impossible for humans. The second is that all nations have their limits. There might be individuals within that group who are willing to sacrifice their lives; it might even be a relatively high number for the population, but that population as a whole will eventually reach its maximum emotional and physiological breaking point. The Japanese reached theirs with a couple of American atomic bombs. The Vietnamese might have reached theirs if we’d dropped a couple more, 2 but, thank all holy Christ, our will broke before it came to that. That is the nature of human warfare, two sides trying to push the other past its limit of endurance, and no matter how much we like to talk about total war, that limit is always there…unless you’re the living dead. For the first time in history, we faced an enemy that was actively waging total war. They had no limits of endurance. They would never negotiate, never surrender. They would fight until the very end because, unlike us, every single one of them, every second of every day, was devoted to consuming all life on Earth. That’s the kind of enemy that was waiting for us beyond the Rockies. That’s the kind of war we had to fight.

These are the two physiological realities upon and out of which the doctrine of salvation has sprung. I call them a sublime super-development of hedonism upon a thoroughly unsalubrious soil. What stands most closely related to them, though with a large admixture of Greek vitality and nerve-force, is epicureanism, the theory of salvation of paganism. Epicurus was a typical décadent: I was the first to recognize him.—The fear of pain, even of infinitely slight pain—the end of this can be nothing save a religion of love....

I had come to see language as an almost supernatural force, existing between people, bringing our brains, shielded in centimeter-thick skulls, into communion. A word meant something only between people, and life's meaning, its virtue, had something to do with the depth of the relationships we form. It was the relational aspect of humans- i.e., "human relationally"- that undergirded meaning. Yet somehow, this process existed in brains and bodies, subject to their own physiologic imperatives, prone to breaking and failing.

Scientists discovered that 82% of subjects tested for COVID-19 in a study had a Vitamin D deficiency. That makes sense. Exposure to sunlight creates Vitamin D in the human body. Sars-CoV-2 is closely related to the bat virus RaTG13 and other viruses in bats, and they live in deep, dark caves and usually only emerge at night. The lack of Vitamin D made those subjects physiologically similar to the natural host (it's alleged COVID mutated in some unknown vector into a more virulent form) and created ideal conditions for zoonosis to occur.

I took care to replace the Compendium in its correct pamphlet, and in doing so dislodged a slim pamphlet by Grastrom, one of the most eccentric authors in Solarist literature. I had read the pamphlet, which was dictated by the urge to understand what lies beyond the individual, man, and the human species. It was the abstract, acidulous work of an autodidact who had previously made a series of unusual contributions to various marginal and rarefied branches of quantum physics. In this fifteen-page booklet (his magnum opus!), Grastrom set out to demonstrate that the most abstract achievements of science, the most advanced theories and victories of mathematics represented nothing more than a stumbling, one or two-step progression from our rude, prehistoric, anthropomorphic understanding of the universe around us. He pointed out correspondences with the human body-the projections of our sense, the structure of our physical organization, and the physiological limitations of man-in the equations of the theory of relativity, the theorem of magnetic fields and the various unified field theories. Grastrom’s conclusion was that there neither was, nor could be any question of ‘contact’ between mankind and any nonhuman civilization. This broadside against humanity made no specific mention of the living ocean, but its constant presence and scornful, victorious silence could be felt between every line, at any rate such had been my own impression. It was Gibarian who drew it to my attention, and it must have been Giarian who had added it to the Station’s collection, on his own authority, since Grastrom’s pamphlet was regarded more as a curiosity than a true contribution to Solarist literature

Michael Pollan: "The industrialization--and dehumanization--of American animal farming is a relatively new, evitable, and local phenomenon: no other country raises and slaughters its food animals quite as intensively or as brutally as we do." U.S. consumers may take our pick of reasons to be wary of the resulting product: growth hormones, antibiotic-resistant bacteria, unhealthy cholesterol composition, deadly E. coli strains, fuel consumption, concentration of manure into toxic waste lagoons, and the turpitude of keeping confined creatures at the limits of their physiological and psychological endurance.

My conception of genius. — Great men, like great ages, are explosives in which a tremendous force is stored up; their precondition is always, historically and physiologically, that for a long time much has been gathered, stored up, saved up, and conserved for them — that there has been no explosion for a long time. Once the tension in the mass has become too great, then the most accidental stimulus suffices to summon into the world the "genius," the "deed," the great destiny. What does the environment matter then, or the age, or the "spirit of the age," or "public opinion"! Take the case of Napoleon. Revolutionary France, and even more, prerevolutionary France, would have brought forth the opposite type; in fact, it did. Because Napoleon was different, the heir of a stronger, older, more ancient civilization than the one which was then perishing in France, he became the master there, he was the only master. Great men are necessary, the age in which they appear is accidental; that they almost always become masters over their age is only because they are stronger, because they are older, because for a longer time much was gathered for them. The relationship between a genius and his age is like that between strong and weak, or between old and young: the age is relatively always much younger, thinner, more immature, less assured, more childish.

by knowledge the privilege to BE! His insight refines him. The beauty of nature shines in his own breast. Man is greater that he can see this, and the universe less, because Time and Space relations vanish as laws are known. Here again we are impressed and even daunted by the immense Universe to be explored. "What we know, is a point to what we do not know." Open any recent journal of science, and weigh the problems suggested concerning Light, Heat, Electricity, Magnetism, Physiology, Geology, and judge whether the interest of natural science is likely to be soon exhausted. Passing by many particulars of the discipline of nature, we must not omit to specify two. The exercise of the Will or the

Whenever I seek the deepest contrast to me, the incalculable baseness of the instincts, I always find my mother and sister — to believe that I am related to such riff-raff would be a blasphemy against my divinity. The treatment I have experienced at the hands of my mother and sister, up until this very moment, introduces in me unspeakable horror: here there is at work a perfect hell machine that, with impeccable accuracy, picks the very moment at which it can inflict a bloody wound, at my highest moments, . . . since then every power is lacking to defend oneself against such a poisonous worm . . . the physiological contiguity makes possible such a pre-established disharmony . . . But I confess that the deepest objection to the 'eternal recurrence,' my most terrible thought, is always my mother and my sister.

First, our emotional state determines where we direct our attention, what we remember, and what we learn. Second is decision making: when we’re in the grip of any strong emotion—such as anger or sadness, but also elation or joy—we perceive the world differently, and the choices we make at that moment are influenced, for better or for worse. Third is our social relations. What we feel—and how we interpret other people’s feelings—sends signals to approach or avoid, to affiliate with someone or distance ourselves, to reward or punish. Fourth is the influence of emotions on our health. Positive and negative emotions cause different physiological reactions within our bodies and brains, releasing powerful chemicals that, in turn, affect our physical and mental well-being. And the fifth has to do with creativity, effectiveness, and performance.

when we consider DNA, the genotype is the DNA sequence that contains instructions for the living organism. The phenotype is the observable characteristics of an organism, such as its anatomy, biochemistry, physiology, and behavior. The genotype interacts with the environment to produce the phenotype. To put this in an everyday situation, consider the blueprint as a house’s genotype and the actual house its phenotype. The phenotypic construction process is the building of the house using the blueprint as information about what and how to do it. The phenotype is related to the genotype that describes it, but there is a world of physical difference between the genotype and the phenotype and even the phenotypic construction process. For one, the genotype is non-dynamic; it is a quiescent, one-dimensional sequence of symbols (DNA’s symbols are nucleotides) that has no energy or time constraints. Like a blueprint, it can sit around for years, as you have probably learned from watching CSI. The genotype dictates what should be constructed (perhaps a really cute dog), but the DNA itself does not look or act anything like a cute dog. On the other hand, the phenotype (the cute dog) is dynamic and uses energy, especially if it is a border collie.

I want you to imagine that you live on a planet where everyone has a skin disease. For two or three thousand years, the people on your planet have suffered the same disease: Their entire bodies are covered by wounds that are infected, and those wounds really hurt when you touch them. Of course, they believe this is a normal physiology of the skin. Even the medical books describe this disease as a normal condition. When the people are born, their skin is healthy, but around three or four years of age, the first wounds start to appear. By the time they are teenagers, there are wounds all over their bodies. Can you imagine how these people are going to treat each other? In order to relate with one another, they have to protect their wounds. They hardly ever touch each other’s skin because it is too painful. If by accident you touch someone’s skin, it is so painful that right away she gets angry and touches your skin, just to get even. Still, the instinct to love is so strong that you pay a high price to have relationships with others. Well, imagine that a miracle occurs one day. You awake and your skin is completely healed. There are no wounds anymore, and it doesn’t hurt to be touched. Healthy skin you can touch feels wonderful because the skin is made for perception. Can you imagine yourself with healthy skin in a world where everyone has a skin disease? You cannot touch others because it hurts them, and no one touches you because they make the assumption that it will hurt you.

Men cooperate with one another. The totality of interhuman relations engendered by such cooperation is called society. Society is not an entity in itself. It is an aspect of human action. It does not exist or live outside of the conduct of people. It is an orientation of human action. Society neither thinks nor acts. Individuais in thinking and acting constitute a complex of relations and facts that are called social relations and facts. The issue has been confused by an arithmetical metaphor. Is society, people asked, merely a sum of individuals or is it more than this and thereby an entity endowed with independent reality? The question is nonsensical. Society is neither the sum of individuais nor more nor less. Arithmetical concepts cannot be applied to the matter. Another confusion arises from the no less empty question whether society is—in logic and in time—anterior to individuais or not. The evolution of society and that of civilization were not two distinct processes but one and the same process. The biological passing of a species of primates beyond the levei of a mere animal existence and their transformation into primitive men implied already the development of the first rudiments of social cooperation. Homo sapiens appeared on the stage of earthly events neither as a solitary foodseeker nor as a member of a gregarious flock, but as a being consciously cooperating with other beings of his own kind. Only in cooperation with his fellows could he develop language, the indispensable tool of thinking. We cannot even imagine a reasonable being living in perfect isolation and not cooperating at least with members of his family, clan, or tribe. Man as man is necessarily a social animal. Some sort of cooperation is an essential characteristic of his nature. But awareness of this fact does not justify dealing with social relations as if they were something else than relations or with society as if it were an independent entity outside or above the actions of individual men. Finally there are the misconstructions caused by the organismic metaphor. We may compare society to a biological organism. The tertium comparationis is the fact that division of labor and cooperation exist among the various parts of a biological body as among the various members of society. But the biological evolution that resulted in the emergence of the structurefunction systems of plant and animal bodies was a purely physiological process in which no trace of a conscious activity on the part of the cells can be discovered. On the other hand, human society is an intellectual and spiritual phenomenon. In cooperating with their fellows, individuais do not divest themselves of their individuality. They retain the power to act antisocially, and often make use of it. Its place in the structure of the body is invariably assigned to each cell. But individuais spontaneously choose the way in which they integrate themselves into social cooperation. Men have ideas and seek chosen ends, while the cells and organs of the body lack such autonomy.

Interactions with the world program our physiological and psychological development. Emotional contact is as important as physical contact. The two are quite analogous, as we recognize when we speak of the emotional experience of feeling touched. Our sensory organs and brains provide the interface through which relationships shape our evolution from infancy to adulthood. Social-emotional interactions decisively influence the development of the human brain. From the moment of birth, they regulate the tone, activity and development of the psychoneuroimmunoendocrine (PNI) super-system. Our characteristic modes of handling psychic and physical stress are set in our earliest years. Neuroscientists at Harvard University studied the cortisol levels of orphans who were raised in the dreadfully neglected child-care institutions established in Romania during the Ceausescu regime. In these facilities the caregiver/child ratio was one to twenty. Except for the rudiments of care, the children were seldom physically picked up or touched. They displayed the self-hugging motions and depressed demeanour typical of abandoned young, human or primate. On saliva tests, their cortisol levels were abnormal, indicating that their hypothalamic-pituitary-adrenal axes were already impaired. As we have seen, disruptions of the HPA axis have been noted in autoimmune disease, cancer and other conditions. It is intuitively easy to understand why abuse, trauma or extreme neglect in childhood would have negative consequences. But why do many people develop stress-related illness without having been abused or traumatized? These persons suffer not because something negative was inflicted on them but because something positive was withheld.

But how did proteins make physiological reactions possible? Hemoglobin, the oxygen carrier in blood, for instance, performs one of the simplest and yet most vital reactions in physiology. When exposed to high levels of oxygen, hemoglobin binds oxygen. Relocated to a site with low oxygen levels, it willingly releases the bound oxygen. This property allows hemoglobin to shuttle oxygen from the lung to the heart and the brain. But what feature of hemoglobin allows it to act as such an effective molecular shuttle? The answer lies in the structure of the molecule. Hemoglobin A, the most intensively studied version of the molecule, is shaped like a four-leaf clover. Two of its “leaves” are formed by a protein called alpha-globin; the other two are created by a related protein, beta-globin.II Each of these leaves clasps, at its center, an iron-containing chemical named heme that can bind oxygen—a reaction distantly akin to a controlled form of rusting. Once all the oxygen molecules have been loaded onto heme, the four leaves of hemoglobin tighten around the oxygen like a saddle clasp. When unloading oxygen, the same saddle-clasp mechanism loosens. The unbinding of one molecule of oxygen coordinately relaxes all the other clasps, like the crucial pin-piece pulled out from a child’s puzzle. The four leaves of the clover now twist open, and hemoglobin yields its cargo of oxygen. The controlled binding and unbinding of iron and oxygen—the cyclical rusting and unrusting of blood—allows effective oxygen delivery into tissues. Hemoglobin allows blood to carry seventyfold more oxygen than what could be dissolved in liquid blood alone. The body plans of vertebrates depend on this property: if hemoglobin’s capacity to deliver oxygen to distant sites was disrupted, our bodies would be forced to be small and cold. We might wake up and find ourselves transformed into insects.

It may seem paradoxical to claim that stress, a physiological mechanism vital to life, is a cause of illness. To resolve this apparent contradiction, we must differentiate between acute stress and chronic stress. Acute stress is the immediate, short-term body response to threat. Chronic stress is activation of the stress mechanisms over long periods of time when a person is exposed to stressors that cannot be escaped either because she does not recognize them or because she has no control over them. Discharges of nervous system, hormonal output and immune changes constitute the flight-or-fight reactions that help us survive immediate danger. These biological responses are adaptive in the emergencies for which nature designed them. But the same stress responses, triggered chronically and without resolution, produce harm and even permanent damage. Chronically high cortisol levels destroy tissue. Chronically elevated adrenalin levels raise the blood pressure and damage the heart. There is extensive documentation of the inhibiting effect of chronic stress on the immune system. In one study, the activity of immune cells called natural killer (NK) cells were compared in two groups: spousal caregivers of people with Alzheimer’s disease, and age- and health-matched controls. NK cells are front-line troops in the fight against infections and against cancer, having the capacity to attack invading micro-organisms and to destroy cells with malignant mutations. The NK cell functioning of the caregivers was significantly suppressed, even in those whose spouses had died as long as three years previously. The caregivers who reported lower levels of social support also showed the greatest depression in immune activity — just as the loneliest medical students had the most impaired immune systems under the stress of examinations. Another study of caregivers assessed the efficacy of immunization against influenza. In this study 80 per cent among the non-stressed control group developed immunity against the virus, but only 20 per cent of the Alzheimer caregivers were able to do so. The stress of unremitting caregiving inhibited the immune system and left people susceptible to influenza. Research has also shown stress-related delays in tissue repair. The wounds of Alzheimer caregivers took an average of nine days longer to heal than those of controls. Higher levels of stress cause higher cortisol output via the HPA axis, and cortisol inhibits the activity of the inflammatory cells involved in wound healing. Dental students had a wound deliberately inflicted on their hard palates while they were facing immunology exams and again during vacation. In all of them the wound healed more quickly in the summer. Under stress, their white blood cells produced less of a substance essential to healing. The oft-observed relationship between stress, impaired immunity and illness has given rise to the concept of “diseases of adaptation,” a phrase of Hans Selye’s. The flight-or-fight response, it is argued, was indispensable in an era when early human beings had to confront a natural world of predators and other dangers. In civilized society, however, the flight-fight reaction is triggered in situations where it is neither necessary nor helpful, since we no longer face the same mortal threats to existence. The body’s physiological stress mechanisms are often triggered inappropriately, leading to disease. There is another way to look at it. The flight-or-fight alarm reaction exists today for the same purpose evolution originally assigned to it: to enable us to survive. What has happened is that we have lost touch with the gut feelings designed to be our warning system. The body mounts a stress response, but the mind is unaware of the threat. We keep ourselves in physiologically stressful situations, with only a dim awareness of distress or no awareness at all.

If we want to sum up the value of the priestly existence in the shortest slogan, we could at once put it like this: the priest is the person who alters the direction of ressentiment. For every suffering person instinctively seeks a cause for his suffering, or, more precisely, an agent, or, even more precisely, a guilty agent sensitive to suffering — in short, he seeks some living person on whom he can, on some pretext or other, unload his feelings, either in fact or in effigy: for the discharge of feelings is the most important way a suffering man seeks relief — that is, some anaesthetic — it’s his involuntarily desired narcotic against any kind of torment. In my view, only here can we find the true physiological cause of ressentiment, revenge, and things related to them, in a longing for some anaesthetic against pain through one’s emotions. People usually look for this cause, most incorrectly, in my opinion, in the defensive striking back, a merely reactive protective measure, a “reflex movement” in the event of some sudden damage and threat, of the sort a decapitated frog still makes in order to get rid of corrosive acid. But the difference is fundamental: in one case, people want to prevent suffering further damage; in the other case, people want to deaden a tormenting, secret pain which is becoming unendurable by means of a more violent emotion of some kind and, for the moment at least, to drive it from their consciousness — for that they need some emotion, as unruly an emotion as possible, and, in order to stimulate that, they need the best pretext available. “Someone or other must be guilty of the fact that I am ill” — this sort of conclusion is characteristic of all sick people, all the more so if the real cause of their sense that they are sick, the physiological cause, remains hidden (—it can lie, for example, in an illness of the nervus sympathicus [sympathetic nerve], or in an excessive secretion of gall, or in a lack of potassium sulphate and phosphate in the blood, or in some pressure in the lower abdomen, which blocks the circulation, or in a degeneration of the ovaries, and so on).

Rape has been described by victim advocate and former police officer Tom Tremblay as “the most violent crime a person can survive.”10 Those who have not been sexually assaulted can perhaps most clearly understand the experience of a survivor by thinking of them as having survived an attempted murder that used sex as the weapon. Sexual violence often doesn’t look like what we think of as “violence”—only rarely is there a gun or knife; often there isn’t even “aggression” as we typically think of it. There is coercion and the removal of the targeted person’s choice about what will happen next. Survivors don’t “fight” because the threat is too immediate and inescapable; their bodies choose “freeze” because it’s the stress response that maximizes the chances of staying alive . . . or of dying without pain. Trauma isn’t always caused by one specific incident. It can also emerge in response to persistent distress or ongoing abuse, like a relationship where sex is unwanted, though it may be technically “consensual” because the targeted person says yes in order to avoid being hurt or feels trapped in the relationship or is otherwise coerced. In that context, a survivor’s body gradually learns that it can’t escape and it can’t fight; freeze becomes the default stress response because of the learned pattern of shutdown as the best way to guarantee survival. Each person’s experience of survival is unique, but it often includes a kind of disengaged unreality. And afterward, that illusion of unreality gradually degrades, disintegrating under the weight of physical existence and burdened memory. The tentative recognition that this thing has actually happened incrementally unlocks the panic and rage that couldn’t find their way to the surface before, buried as they were under the overmastering mandate to survive. But survival is not recovery; survival happens automatically, sometimes even against the survivor’s will. Recovery requires an environment of relative security and the ability to separate the physiology of freeze from the experience of fear, so that the panic and the rage can discharge, completing their cycles at last.

What, then, is addiction? In the words of a consensus statement by addiction experts in 2001, addiction is a “chronic neurobiological disease… characterized by behaviors that include one or more of the following: impaired control over drug use, compulsive use, continued use despite harm, and craving.” The key features of substance addiction are the use of drugs or alcohol despite negative consequences, and relapse. I’ve heard some people shrug off their addictive tendencies by saying, for example, “I can’t be an alcoholic. I don’t drink that much…” or “I only drink at certain times.” The issue is not the quantity or even the frequency, but the impact. “An addict continues to use a drug when evidence strongly demonstrates the drug is doing significant harm…. If users show the pattern of preoccupation and compulsive use repeatedly over time with relapse, addiction can be identified.” Helpful as such definitions are, we have to take a broader view to understand addiction fully. There is a fundamental addiction process that can express itself in many ways, through many different habits. The use of substances like heroin, cocaine, nicotine and alcohol are only the most obvious examples, the most laden with the risk of physiological and medical consequences. Many behavioural, nonsubstance addictions can also be highly destructive to physical health, psychological balance, and personal and social relationships. Addiction is any repeated behaviour, substance-related or not, in which a person feels compelled to persist, regardless of its negative impact on his life and the lives of others. Addiction involves: 1. compulsive engagement with the behaviour, a preoccupation with it; 2. impaired control over the behaviour; 3. persistence or relapse, despite evidence of harm; and 4. dissatisfaction, irritability or intense craving when the object — be it a drug, activity or other goal — is not immediately available. Compulsion, impaired control, persistence, irritability, relapse and craving — these are the hallmarks of addiction — any addiction. Not all harmful compulsions are addictions, though: an obsessive-compulsive, for example, also has impaired control and persists in a ritualized and psychologically debilitating behaviour such as, say, repeated hand washing. The difference is that he has no craving for it and, unlike the addict, he gets no kick out of his compulsion. How does the addict know she has impaired control? Because she doesn’t stop the behaviour in spite of its ill effects. She makes promises to herself or others to quit, but despite pain, peril and promises, she keeps relapsing. There are exceptions, of course. Some addicts never recognize the harm their behaviours cause and never form resolutions to end them. They stay in denial and rationalization. Others openly accept the risk, resolving to live and die “my way.

The Western medical model — and I don't mean the science of it, I mean the practice of it, because the science is completely at odds with the practice — makes two devastating separations. First of all we separate the mind from the body, we separate the emotions from the physiology. So we don't see how the physiology of people reflects their lifelong emotional experience. So we separate the mind from the body, which is not something that traditional medicine has done, I mean, Ayuverdic or Chinese medicine or shamanic tribal cultures and medicinal practices throughout the world have always recognized that mind and body are inseparable. They intuitively knew it. Many Western practitioners have known this and even taught it, but in practice we ignore it. And then we separate the individual from the environment. The studies are clear, for example, that when people are emotionally isolated they tend to get sick more quickly and they succumb more rapidly to their disease. Why? Because people's physiology is completely related to their psychological, social environment and when people are isolated and alone their stress levels are much higher because there's nothing there to help them moderate their stress. And physiologically it is straightforward, you know, it takes a five-year-old kid to understand it. However because in practice we separate them... when somebody shows up with an inflamed joint, all we do is we give them an anti-inflammatory or because the immune system is hyperactive and is attacking them we give them a medication to suppress their immune system or we give them a stress hormone like cortisol or one of its analogues, to suppress the inflammation. But we never ask: "What does this manifest about your life?", "What does this say about your relationships?", "How stressful is your job?", "To what extent do you lack control in your life?", "Where are you not authentic?", "How are you trying to work so hard to meet your attachment needs by suppressing yourself?" (because that is what you learn to do as a kid). Then we do all this research that has to do with cell biology, so we keep looking for the cause of cancer in the cell. Now there's a wonderful quote in the New York Times a couple of years ago they did a series on cancer and somebody said: "Looking for the cause of cancer inside the individual cell is like trying to understand a traffic jam by studying the internal combustion engine." We will never understand it, but we spend hundreds of billions of dollars a year looking for the cause of cancer inside the cell, not recognizing that the cell exists in interaction with the environment and that the genes are modulated by the environment, they are turned on and off by the environment. So the impact of not understanding the unity of emotions and physiology on one hand and in the other hand the relationship between the individual and the environment.. in other words.. having a strictly biological model as opposed to what has been called a bio-psycho-social, that recognizes that the biology is important, but it also reflects our psychological and social relationships. And therefore trying to understand the biology in isolation from the psychological and social environment is futile. The result is that we are treating people purely through pharmaceuticals or physical interventions, greatly to the profit of companies that manufacture pharmaceuticals and which fund the research, but it leaves us very much in the dark about a) the causes and b) the treatment, the holistic treatment of most conditions. So that for all our amazing interventions and technological marvels, we are still far short of doing what we could do, were we more mindful of that unity. So the consequences are devastating economically, they are devastating emotionally, they are devastating medically.

The traditional hospital practice of excluding parents ignored the importance of attachment relationships as regulators of the child’s emotions, behaviour and physiology. The child’s biological status would be vastly different under the circumstances of parental presence or absence. Her neurochemical output, the electrical activity in her brain’s emotional centres, her heart rate, blood pressure and the serum levels of the various hormones related to stress would all vary significantly. Life is possible only within certain well-defined limits, internal or external. We can no more survive, say, high sugar levels in our bloodstream than we can withstand high levels of radiation emanating from a nuclear explosion. The role of self-regulation, whether emotional or physical, may be likened to that of a thermostat ensuring that the temperature in a home remains constant despite the extremes of weather conditions outside. When the environment becomes too cold, the heating system is switched on. If the air becomes overheated, the air conditioner begins to work. In the animal kingdom, self-regulation is illustrated by the capacity of the warm-blooded creature to exist in a broad range of environments. It can survive more extreme variations of hot and cold without either chilling or overheating than can a coldblooded species. The latter is restricted to a much narrower range of habitats because it does not have the capacity to self-regulate the internal environment. Children and infant animals have virtually no capacity for biological self-regulation; their internal biological states—heart rates, hormone levels, nervous system activity — depend completely on their relationships with caregiving grown-ups. Emotions such as love, fear or anger serve the needs of protecting the self while maintaining essential relationships with parents and other caregivers. Psychological stress is whatever threatens the young creature’s perception of a safe relationship with the adults, because any disruption in the relationship will cause turbulence in the internal milieu. Emotional and social relationships remain important biological influences beyond childhood. “Independent self-regulation may not exist even in adulthood,” Dr. Myron Hofer, then of the Departments of Psychiatry and Neuroscience at Albert Einstein College of Medicine in New York, wrote in 1984. “Social interactions may continue to play an important role in the everyday regulation of internal biologic systems throughout life.” Our biological response to environmental challenge is profoundly influenced by the context and by the set of relationships that connect us with other human beings. As one prominent researcher has expressed it most aptly, “Adaptation does not occur wholly within the individual.” Human beings as a species did not evolve as solitary creatures but as social animals whose survival was contingent on powerful emotional connections with family and tribe. Social and emotional connections are an integral part of our neurological and chemical makeup. We all know this from the daily experience of dramatic physiological shifts in our bodies as we interact with others. “You’ve burnt the toast again,” evokes markedly different bodily responses from us, depending on whether it is shouted in anger or said with a smile. When one considers our evolutionary history and the scientific evidence at hand, it is absurd even to imagine that health and disease could ever be understood in isolation from our psychoemotional networks. “The basic premise is that, like other social animals, human physiologic homeostasis and ultimate health status are influenced not only by the physical environment but also by the social environment.” From such a biopsychosocial perspective, individual biology, psychological functioning and interpersonal and social relationships work together, each influencing the other.

Several studies have demonstrated men’s preference for symmetrical women. In one study, asymmetry was found to be inversely related to male judgments of attractiveness (Singh, 1995). Compared to women, men rate women’s facial attractiveness as rapidly and harshly declining with age (Henss, 1991). In addition, older men more than younger men have been found to prefer the scent of symmetrical women when the women are at high risk of conception (as measured by timing of their ovulatory cycle) (Thornhill et al., 2003). It is known that chemicals similar to estrogen stimulate hypothalamic responses in men but not in women, suggesting that males may have an evolved mechanism to specifically detect ovulatory cues (Savic, Berglund, Gulyas, & Roland., 2001). Other studies suggest that men show olfactory sexual responses to couplins (sex pheromones) that may be present in the vaginal secretions of fertile women (Grammer & Jutte, 1997). However, these results are attenuated by other studies that have not found a relationship between the “scent of symmetry” among women’s and men’s mate preference (Thornhill et al., 2003; Thornhill & Gangestad, 1999). Other physiological measures such as neuroimaging techniques have found that “attractive” (symmetrical) women’s faces stimulated reward-areas of the brains of male subjects, whereas average women and men’s faces did not, suggesting that symmetrical is pleasing (Aharon, Etcoff, Ariely, Chabris, O’Connor, & Breiter, 2001). Taken together, such findings suggest that men’s partner-evaluation mechanisms are tuned to facial symmetry, which declines with age. That symmetry increases when women are most fertile also supports the notion that symmetry is tied to male mate-choice and that women signal their fitness through symmetry.

In addition, participants were entirely unaware that their performance was being affected by their own future perceptions, suggesting that unconscious nervous system activity may be used to detect precognitive perceptions. Studies relying on unconscious responses may be more effective than those relying on conscious responses by bypassing psychological defense mechanisms that may filter out psi perceptions from ordinary awareness.8 Future Feelings In a recent series of experiments conducted in our laboratory at the University of Nevada, Las Vegas, we’ve explored unconscious nervous system responses to future events. Strictly speaking, such responses are a subset of precognition known as “presentiment,” a vague sense or feeling of something about to occur but without any conscious awareness of a particular event.9 The unconscious responses studied in our experiments took advantage of a well-known psychophysical reflex known as the “orienting response,” first described by Pavlov in the 1920s. The orienting response is a set of physiological changes experienced by an organism when it faces a “fight or flight” situation. For human beings, the response also appears in less dangerous contexts, such as when confronting a novel or unexpected stimulus. The classical orienting response is a series of simultaneous bodily changes that include dilation of the pupil, altered brain waves, a rise in sweat gland activity, a rise/fall pattern in heart rate, and blanching of the extremities.10 These bodily changes momentarily sharpen our perceptions, improve our decision-making abilities, increase our strength, and reduce the danger of bleeding. This makes sense from an evolutionary perspective because when our ancestors were challenged by a tiger, the ones who survived were suddenly able to see and hear exceptionally well, make very fast decisions, become unusually strong, and not bleed as easily as usual. It’s relatively easy to produce an orienting response on demand by showing a person an emotionally provocative photograph. Stimuli like noxious odors, meaningful words, electrical shocks, and sudden tactile stimuli are also effective. Because a person’s general level of arousal is affected cumulatively by successive stimuli, the strength of the orienting response tends to diminish after three to five emotional pictures in a row. In our study, to prevent participants from “habituating,” we randomly interspersed the photos used to produce the orienting responses within a pool of twice as many calm photos.

Consider this: Siamese cats possess genes that give the coat its characteristic coloring. The genes, however, are not set in stone, but rather express themselves conditionally in relation to the environment because they are temperature-sensitive. They are “switched on” in colder areas of the body (the brown tail tip, nose, ears, and feet) and turned off in warmer areas. If you raise a Siamese kitten in a very cool climate, it will be darker brown. In a warmer climate, it will look lighter. Thus, two cats with the same genetic makeup end up with a different phenotype, i.e., physiological expression of those genes.

To psychology, however defined, specification of the net would contribute all that could be achieved in that field—even if the analysis were pushed to ultimate psychic units or “psychons,” for a psychon can be no less than the activity of a single neuron. Since that activity is inherently propositional, all psychic events have an intentional, or “semiotic,” character. The “all-or-none” law of these activities, and the conformity of their relations to those of the logic of propositions, insure that the relations of psychons are those of the two-valued logic of propositions. Thus in psychology, introspective, behavioristic or physiological, the fundamental relations are those of two-valued logic.

And your children will push your buttons. They are genetically, evolutionarily, physiologically, developmentally, relationally, psychologically, and emotionally wired to jam their sticky little fingers into your buttons every chance they get. Some kids push harder and faster than other kids, but they all push. It doesn’t mean they secretly despise you. It just means they’re your kids.

傷害自己的事：歷史上，心理學家曾以不同用語指稱看來相似的小對話相關過程（例如「芻思」、「事件後處理」（post-event processing）、「慣性負面自我思考」（habitual negative self-thinking）、「慢性壓力」和「憂慮」）。雖然在某些情況中，這些不同的重複性負面思考有微妙不同（例如，芻思的焦點往往是過去，而憂慮則是未來導向），但科學家在討論時往往將它們視為屬於同一個單一構念，即「固著認知」（perseverative cognition）或「負面重複思考」。我在本書中以「小對話」一詞表達這個概念。這些議題的相關討論請見Jos F. Brosschot, William Gerin, and Julian F. Thayer,“The Perseverative Cognition Hypothesis: A Review of Worry, Prolonged Stress-Related Physiological Activation, and Health,”Journal of Psychosomatic Research 60 (2006): 113–124；and Edward R. Watkins,“Constructive and Unconstructive Repetitive Thought,”Psychological Bulletin 134 (2008): 163–206。

THERE IS A LINE among the fragments of the Greek poet Archilochus which says: ‘The fox knows many things, but the hedgehog knows one big thing.’2 Scholars have differed about the correct interpretation of these dark words, which may mean no more than that the fox, for all his cunning, is defeated by the hedgehog’s one defence. But, taken figuratively, the words can be made to yield a sense in which they mark one of the deepest differences which divide writers and thinkers, and, it may be, human beings in general. For there exists a great chasm between those, on one side, who relate everything to a single central vision, one system, less or more coherent or articulate, in terms of which they understand, think and feel – a single, universal, organising principle in terms of which alone all that they are and say has significance – and, on the other side, those who pursue many ends, often unrelated and even contradictory, connected, if at all, only in some de facto way, for some psychological or physiological cause, related to no moral or aesthetic principle. These last lead lives, perform acts and entertain ideas that are centrifugal rather than centripetal; their thought is scattered or diffused, moving on many levels, seizing upon the essence of a vast variety of experiences and objects for what they are in themselves, without, consciously or unconsciously, seeking to fit them into, or exclude them from, any one unchanging, all-embracing, sometimes self-contradictory and incomplete, at times fanatical, unitary inner vision. The first kind of intellectual and artistic personality belongs to the hedgehogs, the second to the foxes; and without insisting on a rigid classification, we may, without too much fear of contradiction, say that, in this sense, Dante belongs to the first category, Shakespeare to the second; Plato, Lucretius, Pascal, Hegel, Dostoevsky, Nietzsche, Ibsen, Proust are, in varying degrees, hedgehogs; Herodotus, Aristotle, Montaigne, Erasmus, Molière, Goethe, Pushkin, Balzac, Joyce are foxes.

Obviously, under primitive planetary conditions — finite space and finite resources — the illth was perceived as necessary to protect the wealth. Territorial politics are much the same among domesticated primates as among other mammals; the primates are just smarter at building more omni-lethal weapons faster. This was originally a survival trait, an Evolutionary Relative Success, because primates are born without the physiological, inbuilt weaponry (lethal teeth, claws, horns etc.) of other mammals.

She holds up a finger for each teacher as she says, "Your pilates professor has an Only Fans account, which is against school policy. Your economics professor has a mistress, as does your Human Physiology professor. Your Russian professor employs undocumented workers, some of whom live at his house. Your criminology professor enjoys the company of female students a little too much, and your International Relations professor is a high functioning alcoholic. That water bottle isn't full of water.

This process of exploration is in service of disidentification. As introduced in chapter 2, disidentification is the process of a person bringing a quality of mindfulness to their consciousness, taking their thoughts and reactions less seriously, not presuming that what they feel is truth, recognizing they aren’t defined by who they’ve taken themselves to be, and ultimately, dissolving their adaptive survival styles. As these old patterns of identity distortion and physiological dysregulation begin to quiet down, people begin seeing themselves less through the filters of their survival style identifications. This helps clients shift out of child consciousness into adult consciousness. Through inquiry, clients receive support and guidance to connect with what’s real for them in the here and now.

PTSD focuses on experiences of safety, related to life-and-death threat, and the symptoms associated with physiological dysregulation. C-PTSD focuses on experiences of inner security, related to the threat of the Self, and the symptoms associated with psychobiological disorganization.

untrained seniors can build muscle and strength comparable to masters athletes who have been training for decades.11 Another study from the Canadian Journal of Applied Physiology found that the primary driver of age-related muscle loss (sarcopenia) was not age itself but reduced neuromuscular activity.

Communal solidarity absorbs and snuffs out any personal distinction or intelligence and this task is relatively easy where it concerns the majority of the parts of the village: the real problem becomes what to do with the young males. In every way they represent a threat to the established customs and the physiological torpor that benefits the old and the women. The social problem in primitive tribes as well as most civilized and unfree societies becomes this, what to do with the young males, their aggression, their sexual instincts: in every way they must be broken and subsumed for the benefit of the tribe. This is more or less easy for the majority, who lack life force in any significant quantity, harder for the remainder, and where impossible—the fate of the outcast, or, more likely, death. You fool yourself if you imagine that “young males are needed for protection from external threat.” In fact most societies of the settled, primitive and as well as civilized, are more than willing to accept the risk of submission to an alien tribe.

After trauma the world is experienced with a different nervous system that has an altered perception of risk and safety. Porges coined the word “neuroception” to describe the capacity to evaluate relative danger and safety in one’s environment. When we try to help people with faulty neuroception, the great challenge is finding ways to reset their physiology, so that their survival mechanisms stop working against them. This means helping them to respond appropriately to danger but, even more, to recover the capacity to experience safety, relaxation, and true reciprocity.

Trauma is not an artificial concept. Trauma is a very real and complex psychological and physiological phenomena studied and understood within the fields of psychology, psychiatry, and related disciplines, and it is recognized as a significant aspect of human experience.

Most instincts are allied to specialized organs, it is true, but it is nonetheless true that perception and acquired behavior, including the higher types of operative intelligence, do, in a more supple way, manifest certain functional possibilities or "reaction norms" of the anatomical and physiological structure of the species. In a word, the general coordinations of action upon which the building up of most basic types of knowledge is conditional, presuppose not only nervous coordinations but coordinations of a much more deep-seated kind, those which are, in fact, interactions dominating the entire morphogenesis.

Physiologically, man in the normal use of technology (or his variously extended body) is perpetually modified by it and in turn finds ever new ways of modifying his technology. Man becomes, as it were, the sex organs of the machine world, as the bee of the plant world, enabling it to fecundate and to evolve ever new forms. The machine world reciprocates man’s love by expediting his wishes and desires, namely, in providing him with wealth. One of the merits of motivation research has been the revelation of man’s sex relation to the motor car.

The impulse to be looking constantly with central vision is part of a psychophysical syndrome which includes spinal fixation as another characteristic. Tunnel vision -- the use of the macula, or central portion of the retina, to the relative exclusion of the surrounding area -- is hard on/eyes and diminishes their visual potential; it accentuates selective fixation upon objects one after another, missing the whole view and seeing objects as separate from their larger context. It accompanies and fortifies a tunneling habit of mind, a tendency to, fasten onto particular issues or circumstances, to hold doggedly and sometimes with exaggerated emotionality to a point of view, and to be unable to contextualize or to find fresh responses.

the practitioner perceives the inner activity of the body as the manifestation of numerous energy currents (rlung). The term rlung literally means “moving air,” such as the “wind,” or the “breath.” Here it refers to subtle energy currents that move throughout the body. They move in channels (rtsa), which become increasingly discernible with experience. The quality of movement of these currents as well as their direction are correlated with both the rhythm of the breath and the flow of events within the mental continuum. The more chaotic the elaboration of thought within the mental continuum, the greater the disorganization of energy flow within the body. There are five main channels (rlung lnga) as well as numerous subsidiary ones (yan lag gi rlung) described in the Buddhist tantras. Each of the five main channels is associated with one of the five elements (’byung ba lnga), one of the five conflicting emotional states (nyon mong), one of the coarse bodily functions, and one of the body points. Table 6 gives these correlations. TABLE 6: CORRELATION OF ENERGY CURRENTS WITH BODY POINTS AND PHYSIOLOGICAL FUNCTIONSa Name of Energy Current Related Body Points Physiological Function 1. Inspiration (thur sel) Crossed legs Excretion 2. Expiration (kyen rgyu) Hands in equipose Speaking 3. Firelike (me mnyam) Spine and upper trunk Digestion 4. All-pervasive (khyab byed) Neck and tongue Muscular activity 5. Vital force (srog ’dzin) Gaze Breathing a

In the Base period, when training volume is relatively high and intensity is low, eating a diet rich in “good” fats is beneficial to improving your ability to burn fat for fuel while conserving glycogen stores—a physiological goal of training at this time of the season.

Science and philosophy have for centuries been sustained by unquestioning faith in perception. Perception opens a window on to things. This means that it is directed, quasi-teleologically, towards a *truth in itself* in which the reason underlying all appearances is to be found. The tacit thesis of perception is that at every instant experience can be co-ordinated with that of the previous instant and that of the following, and my perspective with that of other consciousnesses—that all contradictions can be removed, that monadic and intersubjective experience is one unbroken text—that what is now indeterminate for me could become determinate for a more complete knowledge, which is as it were realized in advance in the thing, or rather which is the thing itself. Science has first been merely the sequel or amplification of the process which constitutes perceived things. Just as the thing is the invariant of all sensory fields and of all individual perceptual fields, so the scientific concept is the means of fixing and objectifying phenomena. Science defined a theoretical state of bodies not subject to the action of any force, and *ipso facto* defined force, reconstituting with the aid of these ideal components the processes actually observed. It established statistically the chemical properties of pure bodies, deducing from these those of empirical bodies, and seeming thus to hold the plan of creation or in any case to have found a reason immanent in the world. The notion of geometrical space, indifferent to its contents, that of pure movement which does not by itself affect the properties of the object, provided phenomena with a setting of inert existence in which each event could be related to physical conditions responsible for the changes occurring, and therefore contributed to this freezing of being which appeared to be the task of physics. In thus developing the concept of the thing, scientific knowledge was not aware that it was working on a presupposition. Precisely because perception, in its vital implications and prior to any theoretical thought, is presented as perception of a being, it was not considered necessary for reflection to undertake a genealogy of being, and it was therefore confined to seeking the conditions which make being possible. Even if one took account of the transformations of determinant consciousness, even if it were conceded that the constitution of the object is never completed, there was nothing to add to what science said of it; the natural object remained an ideal unity for us and, in the famous words of Lachelier, a network of general properties. It was no use denying any ontological value to the principles of science and leaving them with only a methodical value, for this reservation made no essential change as far as philosophy was concerned, since the sole conceivable being remained defined by scientific method. The living body, under these circumstances, could not escape the determinations which alone made the object into an object and without which it would have had no place in the system of experience. The value predicates which the reflecting judgment confers upon it had to be sustained, in being, by a foundation of physico-chemical properties. In ordinary experience we find a fittingness and a meaningful relationship between the gesture, the smile and the tone of a speaker. But this reciprocal relationship of expression which presents the human body as the outward manifestation of a certain manner of being-in-the-world, had, for mechanistic physiology, to be resolved into a series of causal relations.” —from_Phenomenology of Perception_. Translated by Colin Smith, pp. 62-64 —Artwork by Cristian Boian

Rorschach’s dissertation, which he finished in 1912, set out to define the physiological pathways that make empathy in Vischer’s sense possible. “On ‘Reflex Hallucinations’ and Related Phenomena” may be a brain-numbing title in English, but the subject was nothing less than the connection between what we see and how we feel. Reflexhalluzination was a technical psychiatric

Indeed, Aristotle makes as many mistakes as possible for a man who is founding the science of biology. He thinks, for example, that the male element in reproduction merely stimulates and quickens; it does not occur to him (what we now know from experiments in parthenogenesis) that the essential function of the sperm is not so much to fertilize the ovum as to provide the embryo with the heritable qualities of the male parent, and so permit the offspring to be a vigorous variant, a new admixture of two ancestral lines. As human dissection was not practised in his time, he is particularly fertile in physiological errors: he knows nothing of muscles, not even of their existence; he does not distinguish arteries from veins; he thinks the brain is an organ for cooling the blood; he believes, forgivably, that man has more sutures in the skull than woman; he believes, less forgivably, that man has only eight ribs on each side; he believes, incredibly, and unforgivably, that woman has fewer teeth than man.25 Apparently his relations with women were of the most amicable kind.

all of whom had questioned their fat patients extensively about their diets. Their common finding was an excessive consumption of starches and sweets. Rony reported that the craving for sweets and starches among his patients was so common that it suggested an underlying physiological mechanism at work, possibly related to a greater need for or reduced availability of glucose.

Decision-making compresses trial-and-error learning experiences into an instantaneous mental evaluation about what the consequence of a particular action will be for a given situation. It requires the on-line integration of information from diverse sources: perceptual information about the stimulus and situation, relevant facts and experiences stored in memory, feedback from emotional systems and the physiological consequences of emotional arousal, expectations about the consequences of different courses of action, and the like. This sort of integrative processing, as we've seen is the business of working memory circuits in the prefrontal cortex. In chapters 7 and 8 , we discussed the role of the prefrontal cortex in working memory and considered the contribution of the lateral and medial prefrontal cortex. Here, we will focus on two of the subareas of the medial prefrontal cortex in light of their relation to the motive circuits outlined above.

The Second Law indicates that not all the processes compatible with the First Law can actually occur. Whereas one can easily perform work to heat up the system, it is not always enough to supply heat to increase the mechanical energy. At least two heat sources at different temperatures are needed, as shown by Carnot’s argument (sometimes one of the sources may be naturally supplied by the environment). Essentially the Second Law states that heat can never pass from a colder to a warmer body without some other related change occurring at the same time (see also the next chapter). The new ideas were propagated in a rapid fashion thanks to the lively and elegant exposition by Thomson [17]. The conservation of energy in the atomic model found its final treatment in the hands of Hermann von Helmholtz (1821–94), who, like Mayer, started from physiological considerations, and about whom we spoke in detail in the previous chapter. In his fundamental work of 1847 [18] he explicitly introduced the concept of potential energy.

Diaphysis A tubular diaphysis (di-af9ĭ-sis; dia 5 through, physis 5 growth), or shaft, forms the long axis of the bone. It is constructed of a relatively thick collar of compact bone that surrounds a central medullary cavity (med9u-lar-e; “middle”), or marrow cavity. In adults, the medullary cavity contains fat (yellow marrow) and is called the yellow marrow cavity.

This is a book about restoring connection. It is the experience of being in connection that fulfills the longing we have to feel fully alive. An impaired capacity for connection to self and others, and the ensuing diminished aliveness, are the hidden dimensions that underlie most psychological and many physiological problems. Unfortunately, we are often unaware of the internal roadblocks that keep us from experiencing the connection and aliveness we yearn for. These roadblocks develop in reaction to developmental and shock trauma and the related nervous system dysregulation, disruptions in attachment, and distortions of identity.

The Mantle of Science For a decade or so, A.A. grew modestly. But, lacking scientific confirmation, it remained a relatively small sectarian movement, occasionally receiving a boost in popular magazines. The great surge in the popularity of the A.A. disease concept came when it received what seemed to be impeccable scientific support. Two landmark articles by E. M. Jellinek, published in 1946 and 1952, proposed a scientific understanding of alcoholism that seemed to confirm major elements of the A.A. view.12 Jellinek, then a research professor in applied physiology at Yale University, was a distinguished biostatistician and one of the early leaders in the field of alcohol studies. In his first paper he presented some eighty pages of elaborately detailed description, statistics, and charts that depicted what he considered to be a typical or average alcoholic career. Jellinek cautioned his readers about the limited nature of his data, and he explicitly acknowledged differences among individual drinkers. But from the data's "suggestive" value, he proceeded to develop a vividly detailed hypothesis.

White blood cells are the only fully functional cells in the circulation. Red blood cells have lost their nuclei by the time they enter the bloodstream, and platelets, which also lack a nucleus, are cell fragments that have split off a relatively large parent cell known as a megakaryocyte {mega, extremely large + karyon, kernel + -cyte, cell}.

But the power problem has its roots in anatomy and biochemistry and temperament. Power has to be curbed on the legal and political levels; that’s obvious. But it’s also obvious that there must be prevention on the individual level. On the level of instinct and emotion, on the level of the glands and the viscera, the muscles and the blood. If I can ever find the time, I’d like to write a little book on human physiology in relation to ethics, religion, politics and law.

larynx (pp. 352–354), and (2) smaller intrinsic muscles that control tension in the glottal vocal folds or that open and close the glottis. These smaller muscles insert on the thyroid, arytenoid, and corniculate cartilages. The opening or closing of the glottis involves rotational movements of the arytenoid cartilages. When you swallow, both sets of muscles work together to prevent food or drink from entering the glottis. Food is crushed and chewed into a pasty mass, known as a bolus, before being swallowed. Muscles of the neck and pharynx then elevate the larynx, bending the epiglottis over the glottis, so that the bolus can glide across the epiglottis rather than falling into the larynx. While this movement is under way, the glottis is closed. Foods or liquids that touch the vestibular folds or glottis trigger the coughing reflex. In a cough, the glottis is kept closed while the chest and abdominal muscles contract, compressing the lungs. When the glottis is opened suddenly, a blast of air from the trachea ejects material that blocks the entrance to the glottis. Sound Production How do you produce sounds? Air passing through your open glottis vibrates its vocal folds and produces sound waves. The pitch of the sound depends on the diameter, length, and tension in your vocal folds. The diameter and length are directly related to the size of your larynx. You control the tension by contracting voluntary muscles that reposition the arytenoid cartilages relative to the thyroid cartilage. When the distance increases, your vocal folds tense and the pitch rises. When the distance decreases, your vocal folds relax and the pitch falls. Children have slender, short vocal folds, so their voices tend to be high pitched. At puberty, the larynx of males enlarges much more than that of females. The vocal cords of an adult male are thicker and longer, so they produce lower tones than those of an adult female. Sound production at the larynx is called phonation (fo.-NA .-shun; phone, voice). Phonation is one part of speech production. Clear speech also requires articulation, the modification of those sounds by voluntary movements of other structures, such as the tongue, teeth, and lips to form words. In a stringed instrument, such as a guitar, the quality of the sound produced does not depend solely on the nature of the vibrating string. Rather, the entire instrument becomes involved as the walls vibrate and the composite sound echoes within the hollow body. Similar amplification and resonance take place within your pharynx, oral cavity, nasal cavity, and paranasal sinuses. The combination gives you the particular and distinctive sound of your voice. That sound changes when you have a sinus infection and your nasal cavity and paranasal sinuses are filled with mucus rather than air.

The DSM-V offers a comprehensive set of criteria to define narcissism: A. Significant impairments in personality functioning manifest by: 1. Impairments in self functioning (a or b): a. Identity: Excessive reference to others for self-definition and self-esteem regulation; exaggerated self-appraisal may be inflated or deflated, or vacillate between extremes; emotional regulation mirrors fluctuations in self-esteem. b. Self-direction: Goal-setting is based on gaining approval from others; personal standards are unreasonably high in order to see oneself as exceptional, or too low based on a sense of entitlement; often unaware of own motivations. AND 2. Impairments in interpersonal functioning (a or b): a. Empathy: Impaired ability to recognize or identify with the feelings and needs of others; excessively attuned to reactions of others, but only if perceived as relevant to self; over- or underestimate of own effect on others. b. Intimacy: Relationships largely superficial and exist to serve self-esteem regulation; mutuality constrained by little genuine interest in others experiences and predominance of a need for personal gain. B. Pathological personality traits in the following domain: 1. Antagonism, characterized by: a. Grandiosity: Feelings of entitlement, either overt or covert; self-centeredness; firmly holding to the belief that one is better than others; condescending toward others. b. Attention seeking: Excessive attempts to attract and be the focus of the attention of others; admiration seeking. C. The impairments in personality functioning and the individual’s personality trait expression are relatively stable across time and consistent across situations. D. The impairments in personality functioning and the individual’s personality trait expression are not better understood as normative for the individual’s developmental stage or sociocultural environment. E. The impairments in personality functioning and the individual’s personality trait expression are not solely due to the direct physiological effects of a substance (e.g., a drug of abuse, medication) or a general medical condition (e.g., severe head trauma).7

The preponderance of an altruistic way of valuing is the result of a consciousness of the fact that one is botched and bungled. Upon examination, this point of view turns out to be: "I am not worth much," simply a psychological valuation; more plainly still: it is the feeling of impotence, of the lack of the great self-asserting impulses of power (in muscles, nerves, and ganglia). This valuation gets translated, according to the particular culture of these classes, into a moral or religious principle (the pre-eminence of religious or moral precepts is always a sign of low culture): it tries to justify itself in spheres whence, as far as it is concerned, the notion "value" hails. The interpretation by means of which the Christian sinner tries to understand himself, is an attempt at justifying his lack of power and of self-confidence: he prefers to feel himself a sinner rather than feel bad for nothing: it is in itself a symptom of decay when interpretations of this sort are used at all. In some cases the bungled and the botched do not look for the reason of their unfortunate condition in their own guilt (as the Christian does), but in society: when, however, the Socialist, the Anarchist, and the Nihilist are conscious that their existence is something for which some one must be guilty, they are very closely related to the Christian, who also believes that he can more easily endure his ill ease and his wretched constitution when he has found some one whom he can hold responsible for it. The instinct of revenge and resentment appears in both cases here as a means of enduring life, as a self-preservative measure, as is also the favour shown to altruistic theory and practice. The hatred of egoism, whether it be one's own (as in the case of the Christian), or another's (as in the case of the Socialists), thus appears as a valuation reached under the predominance of revenge; and also as an act of prudence on the part of the preservative instinct of the suffering, in the form of an increase in their feelings of co-operation and unity. ... At bottom, as I have already suggested, the discharge of resentment which takes place in the act of judging, rejecting, and punishing egoism (one's own or that of others) is still a self-preservative measure on the part of the bungled and the botched. In short: the cult of altruism is merely a particular form of egoism, which regularly appears under certain definite physiological circumstances. When the Socialist, with righteous indignation, cries for "justice," "rights," "equal rights," it only shows that he is oppressed by his inadequate culture, and is unable to understand why he suffers: he also finds pleasure in crying; if he were more at ease he would take jolly good care not to cry in that way: in that case he would seek his pleasure elsewhere. The same holds good of the Christian: he curses, condemns, and slanders the "world" and does not even except himself. But that is no reason for taking him seriously. In both cases we are in the presence of invalids who feel better for crying, and who find relief in slander.

In trauma, pain, and anxiety, touch can be a safe, novel stimulus to access new possibilities in our physiology. Touch can help us meet our wordless places in a way that is hard to access through conversation alone. Touch is stranger and more powerful than often assumed. We can learn to be more skillful as we touch inward and touch outward. Feelings that are habitually scary can be re-framed and transcended. Slow, relational touch can help us shift our emotional core and release us to feel alive and connected.

When your tissues are more lax, your joints don’t have the integrity they should because they’re stretched out,” says Dr. Starrett. This impairs your proprioception, the sense of where your limbs are oriented in space and in relation to one another, which is a huge factor in mobility and stability. When you’re not getting that proprioceptive feedback, your movement patterns are thrown

those who had been treated for their stress-related mental conditions with SSRI-type medication—the most widely prescribed class of antidepressants,[*] of which Prozac is probably the most famous—had lower risk for autoimmunity: a clear indication of the bodymind, to use Dr. Candace Pert’s phrasing for the interflow of psychology and physiology in humans, and of the role of emotions in illness.

Schore emphasized that when the caregiver is unable to help the child to regulate either a specific emotion or intense emotions in general, or – worse – that she exacerbates the dysregulation, the child will start to go into a state of hypoaroused dissociation as soon as a threat of dysregulation arises. This temporaily reduces conscious emotional pain in the child living with chronic trauma, but those who characterologically use the emotion-deadening defense of dissociation to cope with stressful interpersonal events subsequently dissociate to defend against both daily stresses, and the stress caused when implicitly held memories of trauma are triggered. In the developing brain, repeated neurological states become traits, so dissociative defense mechanisms are embedded into the core structure of the evolving personality, and become a part of who a person is, rather than what a person does. Dissociation, which appears in the first month of life, seems to be a last resort survival strategy. It represents detachment from an unbearable situation. The infant withdraws into an inner world, avoids eye contact and stares into space. Dissociation triggered by a hypoaroused state results in a constricted state of consciousness, and a void of subjectivity. Being cut off from our emotions impacts our sense of who we are as a person. Our subjective sense of self derives from our unconscious experience of bodily-based emotions and is neurologically constructed in the right brain. If we cannot connect to our bodily emotions then our sense of self is built on fragile foundations. Many who suffered early relational trauma have a disturbed sense of their bodies and of what is happening within them physiologically as well as emotionally. The interview moved along to the topic of how we can possibly master these adverse and potentially damaging relational experiences. Schore replied by explaining that the human brain remains plastic and capable of learning throughout the entire life span, and that with the right therapeutic help and intervention we can move beyond dissociation as our primary defense mechanism, and begin to regulate our emotions more appropriately. When the relationship between the therapist and the client develops enough safety, the therapeutic alliance can act as a growth-facilitating environment that offers a corrective emotional experience via “rewiring” the right brain and associated neurocircuits.

In a series of studies, Julia Lee, a professor at the University of Michigan, found that those who undergo relational best-self activation experience stronger immune responses, enhanced creative problem solving (over 200 percent improvement), and significantly less anxiety and negative physiological arousal.

Evolutionary biologist Robert Sapolsky is an expert on human stress. In Why Zebras Don’t Get Ulcers: A Guide to Stress, Stress-Related Diseases, and Coping,9 now in its third edition, he explains how a fear of the bad things that might happen can cause us harm. When we activate the stress-response out of fear of something that turns out to be real, we congratulate ourselves that this cognitive skill allows us to mobilize our defenses early. And these anticipatory defenses can be quite protective, in that a lot of what the stress-response is about is preparative. But when we get into a physiological uproar and activate the stress-response for no reason at all, or over something we cannot do anything about, we call it things like “anxiety,” “neurosis,” “paranoia,” or “needless hostility.” Thus, the stress-response can be mobilized not only in response to physical or psychological insults, but also in expectation of them. It is this generality of the stress-response that is the most surprising—a physiological system activated not only by all sorts of physical disasters but just thinking about them as well.10 Basically, the 24/7/365/worldwide news cycle is a recent development in human existence and we haven’t evolved to cope with it yet. There is such a thing as too much information.

One way to avoid the design problems encountered by the transcendental meditation researchers would be to keep one of the variables fixed. This could be either the number of meditators or the “target” of consciousness-induced order. Beyond this, as philosopher Evan Fales and sociologist Barry Markovsky of the University of Iowa suggested after reviewing the Maharishi effect, “Presumably, if the material world can be influenced in purposive ways by collective meditation, inanimate detectors could be constructed and placed at varying distances from the collective meditators.”6 This is essentially the approach that we took, although our motivations were based upon a logical extension of laboratory research on mind-matter interactions using random-number generators, and not by the claims of the transcendental meditators. Properties of Consciousness Whatever else consciousness may be, let us suppose that it also has the following properties, derived from a combination of Western and Eastern philosophies.7 The first property is that consciousness extends beyond the individual and has quantum field–like properties, in that it affects the probabilities of events. Second, consciousness injects order into systems in proportion to the “strength” of consciousness present. This is a refinement of quantum physicist Erwin Schrödinger’s observation about one of the most remarkable properties of life, namely, an “organism’s astonishing gift … of ‘drinking orderliness’ from a suitable environment.”8 Third, the strength of consciousness in an individual fluctuates from moment to moment, and is regulated by focus of attention. Some states of consciousness have higher focus than others. We propose that ordinary awareness has a fairly low focus of attention compared to peak states, mystical states, and other nonordinary states.9 Fourth, a group of individuals can be said to have “group consciousness.” Group consciousness strengthens when the group’s attention is focused on a common object or event, and this creates coherence among the group. If the group’s attention is scattered, then the group’s mental coherence is also scattered. Fifth, when individuals in a group are all attending to different things, then the group consciousness and group mental coherence is effectively zero, producing what amounts to background noise. We assume that the maximum degree of group coherence is related in some complicated way to the total number of individuals present in the group, the strength of their common focus of attention, and other psychological, physiological, and environmental factors. Sixth, physical systems of all kinds respond to a consciousness field by becoming more ordered. The stronger or more coherent a consciousness field, the more the order will be evident. Inanimate objects (like rocks) will respond to order induced by consciousness as well as animate ones (like people, or tossed dice), but it is only in the more labile systems that we have the tools to readily detect these changes in order. In sum, when a group is actively focused on a common object, the “group mind” momentarily has the “power to organize,” as Carl Jung put it.10 This leads us to a very simple idea: as the mind moves, so moves matter.

Oprah: It’s nearly impossible for some people to go with the flow, or get along. They blow up at their boss. They’re not reliable as friends. They sabotage new relationships. Dr. Perry: Yet it’s almost always the case that these people really do want to be connected. They may even be good at starting relationships; they’re just terrible at maintaining them. And, of course, since we are, at our core, relational creatures, this difficulty is physiologically and psychologically devastating. It leads to isolation, disconnection, loneliness, and is connected to all kinds of other problems, including risk for physical health problems.

To say that simple life-forms without nervous systems have pain is unnecessary and probably not correct. They certainly have some of the elements required to construct feelings of pain, but it is reasonable to hypothesize that for pain itself to emerge, as a mental experience, the organism needed to have a mind and that for that to pass, the organism needed a nervous system capable of mapping structures and events. In other words, I suspect that life-forms without nervous systems or minds had and have elaborate emotive processes, defensive and adaptive action programs, but not feelings. Once nervous systems entered the scene, the path for feelings was open. That is why even humble nervous systems probably allow some measure of feeling.5 It is often asked, not unreasonably, why feelings should feel like anything at all, pleasant or unpleasant, tolerably quiet or like an uncontainable storm. The reason should now be clear: when the full constellation of physiological events that constitutes feelings began to appear in evolution and provided mental experiences, it made a difference. Feelings made lives better. They prolonged and saved lives. Feelings conformed to the goals of the homeostatic imperative and helped implement them by making them matter mentally to their owner as, for example, the phenomenon of conditioned place aversion appears to demonstrate.6 The presence of feelings is closely related to another development: consciousness and, more specifically, subjectivity.