Pharma Marketing Quotes

Used in combination with genomics, AI could help pharma companies to develop new drugs for rare diseases. The rarer a disease is, the smaller the market is and so the less likely it is to have been addressed. Big pharma is hesitant to take on the high development costs for new drugs if there’s no sign of a return on investment. Biological processes are complex, and that means that they lead to multidimensional data that human beings struggle to wrap their heads around. The good news is that AI is the perfect tool to spot patterns in this kind of data.

Some have estimated that the pharmaceutical industry overall spends about twice as much on marketing and promotion as it does on research and development.

Most people know what constitutes a healthy diet already. If you want to make money out of it, you have to make a space for yourself in the market, and to do this, you must overcomplicate it, attach your own dubious stamp.

No wonder big pharma will do almost anything to protect exclusive marketing rights, despite the fact that doing so flies in the face of all its rhetoric about the free market.

No,” said a third student. “Novartis is a public company. It’s not the boss or the board who decides. It’s the shareholders. If the board changes its priorities the shareholders will just elect a new board.” “That’s right,” I said. “It’s the shareholders who want this company to spend their money on researching rich people’s illnesses. That’s how they get a good return on their shares.” So there’s nothing wrong with the employees, the boss, or the board, then. “Now, the question is”—I looked at the student who had first suggested the face punching—“who owns the shares in these big pharmaceutical companies?” “Well, it’s the rich.” He shrugged. “No. It’s actually interesting because pharmaceutical shares are very stable. When the stock market goes up and down, or oil prices go up and down, pharma shares keep giving a pretty steady return. Many other kinds of companies’ shares follow the economy—they do better or worse as people go on spending sprees or cut back—but the cancer patients always need treatment. So who owns the shares in these stable companies?” My young audience looked back at me, their faces like one big question mark. “It’s retirement funds.” Silence. “So maybe I don’t have to do any punching, because I will not meet the shareholders. But you will. This weekend, go visit your grandma and punch her in the face. If you feel you need someone to blame and punish, it’s the seniors and their greedy need for stable stocks.

So what steps can a regulator take when it has established that there is a problem? In very extreme cases it can remove a drug from the market (although in the US, technically drugs usually stay on the market, with the FDA advising against their use). More commonly it will issue a warning to doctors through one of its drug safety updates, a ‘Dear Doctor’ letter, or by changing the ‘label’ (confusingly, in reality, a leaflet) that comes with the drug. Drug-safety updates are sent to most doctors, though it’s not entirely clear whether they are widely read. But, amazingly, when a regulator decides to notify doctors about a side effect, the drug company can contest this, and delay the notice being sent out for months, or even years.

At this time we should take a brife moment to mention quacks: alternative therapists who sell vitamins and homeopathy sugar pills [the latter of which, by definition, contain no active ingredients], which perform no better than placebo in fair tests, and who use even cruder marketing tricks than the ones described in this book. In these people profit at all from the justified anger that people feel towards the pharmaceutical industry, then it comes at the expense of genuinely constructive activity. Selling ineffective sugar pills is not a meaningful policy response to the regulatory failure we have seen in this book

In medicine, brand identities are irrelevant, and there’s a factual, objective answer to whether one drug is the most likely to improve a patient’s pain, suffering and longevity. Marketing, therefore, one might argue, exists for no reason other than to pervert evidence-based decision-making in medicine.

The detox phenomenon is interesting because it represents one of the most grandiose innovations of marketers, lifestyle gurus, and alternative therapists: the invention of a whole new physiological process. In terms of basic human biochemistry, detox is a meaningless concept. It doesn’t cleave nature at the joints. There is nothing on the “detox system” in a medical textbook. That burgers and beer can have negative effects on your body is certainly true, for a number of reasons; but the notion that they leave a specific residue, which can be extruded by a specific process, a physiological system called detox, is a marketing invention.

Here we will see that pharmaceutical companies spend tens of billions of pounds every year trying to change the treatment decisions of doctors: in fact, they spend twice as much on marketing and advertising as they do on the research and development of new drugs. Since we all want doctors to prescribe medicine based on evidence, and evidence is universal, there is only one possible reason for such huge spends: to distort evidence-based practice.

Thus, if any FDA-approved drug like hydroxychloroquine (or ivermectin) proved effective against COVID, pharmaceutical companies would no longer be legally allowed to fast-track their billion-dollar vaccines to market under Emergency Use Authorization.

As I grew up, I wondered why humans had strayed so far from the understanding of food as medicine, and why there were Big Pharma pharmacies in our food markets. I learned that what I put in and on my body mattered! I came to realize that most of what I purchased or used had negative consequences for people and the planet. This was an affront to my soul.

Consider that the original Star Wars movies—some of the highest-grossing films of all time—required more than forty years to amass $3 billion in revenue. It took Ambien just twenty-four months to amass $4 billion in sales profit, discounting the black market. That’s a large number, and one I can only imagine influences Big Pharma decision-making at all levels.

Dr. Fauci worked with Facebook’s Mark Zuckerberg and other social media sites to muzzle discussion of any remedies. FDA sent a letter of warning that N-acetyle-L-cysteine (NAC) cannot be lawfully marketed as a dietary supplement, after decades of free access on health food shelves, and suppressed IV vitamin C, which the Chinese were using with extreme effectiveness.

The idea that depression is caused by low serotonin levels in the brain is now deeply embedded in popular folklore, and people with no neuroscience background at all will routinely incorporate phrases about it into everyday discussion of their mood, just to keep their serotonin levels up. Many people also don't know that this is how antidepressant drugs work: depression is caused by low serotonin, so you need drugs which raise the serotonin levels in your brain, like SSRI antidepressants, which are 'selective serotonin reuptake inhibitors'. But this theory is wrong. The 'serotonin hypothesis' for depression, as it is known, was always shaky, and the evidence now is hugely contradictory ... But in popular culture the depression-serotonin theory is proven and absolute, because it has been marketed so effectively.

Over the last fifty years at NIH, Dr. Fauci has played a leading role in Big Pharma’s engineered demolition of American health and democracy, working hand in glove with pharmaceutical companies to overcome federal regulatory obstacles and transform the NIH and NIAID into a single-minded vehicle for development, promotion, and marketing of patented pharmaceutical products, including vaccines and vaccine-like products.

the fact is, our relationships to these corporations are not unambiguous. some memebers of negativland genuinely liked pepsi products. mca grew up loving star wars and didn't mind having his work sent all over the united states to all the "cool, underground magazines" they were marketing to--why would he? sam gould had a spiritual moment in the shower listening to a cd created, according to sophie wong, so that he would talk about tylenol with his independent artist friends--and he did. many of my friends' daughters will be getting american girl dolls and books as gifts well into the foreseeable future. some skateboarders in washington, dc, were asked to create an ad campaign for the east coast summer tour, and they all love minor threat--why not use its famous album cover? how about shilling for converse? i would have been happy to ten years ago. so what's really changed? the answer is that two important things have changed: who is ultimately accountable for veiled corporate campaigns that occasionally strive to obsfucate their sponsorship and who is requesting our participation in such campaigns. behind converse and nike sb is nike, a company that uses shit-poor labor policies and predatory marketing that effectively glosses over their shit-poor labor policies, even to an audience that used to know better. behind team ouch! was an underground-savvy brainreservist on the payroll of big pharma; behind the recent wave of street art in hip urban areas near you was omd worldwide on behalf of sony; behind your cool hand-stenciled vader shirt was lucasfilm; and behind a recent cool crafting event was toyota. no matter how you participated in these events, whether as a contributor, cultural producer, viewer, or even critic, these are the companies that profited from your attention.

Some have estimated that the pharmaceutical industry overall spends about twice as much on marketing and promotion as it does on research and development. Regardless of how those two figures compare to each other, the fact that they are in the same ballpark gives one pause, and this is worth mulling over in various contexts. For example, when a drug company refuses to let a developing country have affordable access to a new AIDS drug it’s because – the company says – it needs the money from sales to fund research and development on other new AIDS drugs for the future. If R&D is a fraction of the company’s outgoings, and it spends a similar amount on promotion, then this moral and practical argument doesn’t hold water quite so well.

Some have estimated that the pharmaceutical industry overall spends about twice as much on marketing and promotion as it does on research and development. Regardless of how those two figures compare to each other, the fact that they are in the same ballpark gives one pause, and this is worth mulling over in various contexts. For example, when a drug company refuses to let a developing country have affordable access to a new AIDS drug it’s because – the company says – it needs the money from sales to fund research and development on other new AIDS drugs for the future. If R&D is a fraction of the company’s outgoings, and it spends a similar amount on promotion, then this moral and practical argument doesn’t hold water quite so well. The scale of this spend is fascinating in itself, when you put it in the context of what we all expect from evidence-based medicine, which is that people will simply use the best treatment for the patient. Because when you pull away from the industry’s carefully fostered belief that this marketing activity is all completely normal, and stop thinking of drugs as being a consumer product like clothes or cosmetics, you suddenly realise that medicines marketing only exists for one reason. In medicine, brand identities are irrelevant, and there’s a factual, objective answer to whether one drug is the most likely to improve a patient’s pain, suffering and longevity. Marketing, therefore, one might argue, exists for no reason other than to pervert evidence-based decision-making in medicine.

Bobby wrote, “the Big Tech, Big Data, Big Pharma, Big Carbon and Chemical-Industrial Food plutocrats and their allies in the Military Industrial Complex and Intelligence Apparatus now control our government. These plutocrats have twisted the language of democracy, equity and free markets to transform our exemplary democracy into a corrupt system of corporate crony capitalism. The tragic outcome for America has been a cushy socialism for the rich and a savage and bloody free market for the poor. America has devolved into a corporate kleptocracy addicted to a war economy abroad and a security and surveillance state at home. The upper echelons of the Democratic Party are now pro-censorship, pro-war neocons who wear woke bobbleheads to disguise and soften their belligerent totalitarian agendas for our country and the world.

The most widely cited figure for the number of women suffering from Female Sexual Dysfunction comes from 1999: according to this, some 43 per cent of all women have a medical problem around their sex drive.27 This survey was published in the Journal of the American Medical Association (JAMA), one of the most influential journals in the world. It looked at questionnaire data asking about things like lack of desire for sex, poor lubrication, anxiety over sexual performance, and so on. If you answered ‘yes’ to any one of these questions, you were labelled as having Female Sexual Dysfunction. For the avoidance of any doubt about the influence of this paper, it has – as of a sunny evening in March 2012 – been cited 1,691 times. That is a spectacular number of citations. At the time, no financial interest was declared by the study’s authors. Six months later, after criticism in the New York Times, two of the three authors declared consulting and advisory work for Pfizer.28 The company was gearing up to launch Viagra for the female market at this time, and had lots to gain from more women being labelled as having a medical sexual problem.

By collecting data from the vast network of doctors across the globe, they added dozens of new compounds to the arsenal—all proven effective against COVID-19. Dr. Kory told me that he was deeply troubled that the extremely successful efforts by scores of front-line doctors to develop repurposed medicines to treat COVID received no support from any government in the entire world—only hostility—much of it orchestrated by Dr. Fauci and the US health agencies. The large universities that rely on hundreds of millions in annual funding from NIH were also antagonistic. “We didn’t have a single academic institution come up with a single protocol,” said Dr. McCullough. “They didn’t even try. Harvard, Johns Hopkins, Duke, you name it. Not a single medical center set up even a tent to try to treat patients and prevent hospitalization and death. There wasn’t an ounce of original research coming out of America available to fight COVID—other than vaccines.” All of these universities are deeply dependent on billions of dollars that they receive from NIH. As we shall see, these institutions live in terror of offending Anthony Fauci, and that fear paralyzed them in the midst of the pandemic. “Dr. Fauci refused to promote any of these interventions,” says Kory. “It’s not just that he made no effort to find effective off-the-shelf cures—he aggressively suppressed them.” Instead of supporting McCullough’s work, NIH and the other federal regulators began actively censoring information on this range of effective remedies. Doctors who attempted merely to open discussion about the potential benefits of early treatments for COVID found themselves heavily and inexplicably censored. Dr. Fauci worked with Facebook’s Mark Zuckerberg and other social media sites to muzzle discussion of any remedies. FDA sent a letter of warning that N-acetyle-L-cysteine (NAC) cannot be lawfully marketed as a dietary supplement, after decades of free access on health food shelves, and suppressed IV vitamin C, which the Chinese were using with extreme effectiveness.

Another antiviral drug developed by Dr. Fauci’s shop, remdesivir, provides a recent example of a similar Pharma money-making scheme facilitated by NIAID/NIH. While remdesivir proved worthless against COVID, Dr. Fauci altered the study protocols to give his pet drug the illusion of efficacy.30, 31 Despite opposition from FDA and WHO, Dr. Fauci declared from the White House that remdesivir “will be the standard of care” for COVID, guaranteeing the company a massive global market. Dr. Fauci then overlooked Gilead’s price gouging; the company sold remdesivir for $3,300–$5,000 per dose, during the COVID pandemic. The raw materials to make remdesivir cost Gilead under $10. Medicaid must, by law, cover all FDA-approved drugs, so taxpayers again foot the bill. Through these boondoggles, Anthony Fauci has made himself the leading angel investor of the pharmaceutical industry.

The reason Big Pharma spends so much on small gifts as well as the big ones is well known to marketers, lobbyists, and social psychologists: being given a gift evokes an implicit desire to reciprocate.

When we reconfigure societies to put exchange at their centre, Thomas, we violate our nature. Humans thrived by hunting together, cooking communally, making music and telling stories around a blazing fire at night. Sure, the societies that replaced these communal practices with market exchanges unleashed great powers, allowing them to overwhelm others that did not. But there was a price to pay. Market exchange dissolves what makes us human. It is why our souls feel sick. By allowing exchange value to triumph over doing things together for their own sake – for the sheer hell of it – we end up crying ourselves to sleep at night. It’s what depresses us and enriches the self-help gurus and big pharma.

If any FDA-approved drug like hydroxychloroquine (or ivermectin) proved effective against COVID, pharmaceutical companies would no longer be legally allowed to fast-track their billion-dollar vaccines to market under Emergency Use Authorization. Instead, vaccines would have to endure the years-long delays that have always accompanied methodical safety and efficacy testing, and that would mean less profits, more uncertainty, longer runways to market, and a disappointing end to the lucrative COVID-19 vaccine gold rush. Dr. Fauci has invested $6 billion in taxpayer lucre in the Moderna vaccine alone. His agency is co-owner of the patent and stands to collect a fortune in royalties. At least four of Fauci’s hand-picked deputies are in line to collect royalties of $150,000/year based on Moderna’s success, and that’s on top of the salaries already paid by the American public.

Morris’s research found that flu vaccines often induced fever in children and in pregnant women, and serious harm to the fetus. He worried that there were hidden risks for everyone because the vaccine was “literally loaded with extraneous bacteria.”18 According to Dr. Morris, “There is a great deal of evidence to prove that immunization of children does more harm than good.”19 In what serves as a concise epithet for his crosses, Dr. Morris stated, “There is a close tie between government scientists and manufacturing scientists. My results were hurting the market for flu vaccines.”20

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The word psychiatry derives from Greek roots meaning “soul doctoring”—a noble enterprise. Sadly, psychiatry today has lost touch with its roots. It is now dominated by the biomedical model, which attributes all disturbances of mental and emotional health to imbalances of brain biochemistry, correctable by medication. Big Pharma has taken great advantage of this by marketing an array of drugs to treat depression, anxiety, and major mental illnesses.

Aggressive direct-to-consumer marketing of these drugs certainly accounts for much of their popularity. Big Pharma has convinced many people that ordinary states of sadness represent imbalances in brain chemistry that antidepressant medications can correct. But a growing body of data suggests that for mild to moderate depression, the drugs are no more effective than placebos.

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About a quarter of the money taken by pharmaceutical companies for the drugs they sell is turned around into promotional activity which has, as we will see, a provable impact on doctors' prescribing. So we pay for products, with a huge uplift in price to cover their marketing budgets, and that money is then spent on distorting evidence-based practice, which in turn makes our decisions unnecessarily expensive, and less effective.

pharmaceutical companies spend tens of billions of pounds every year trying to change the treatment decisions of doctors: in fact, they spend twice as much on marketing and advertising as they do on the research and development of new drugs. Since we all want doctors to prescribe medicine based on evidence, and evidence is universal, there is only one possible reason for such huge spends: to distort evidence-based practice.

Thus, if any FDA-approved drug like hydroxychloroquine (or ivermectin) proved effective against COVID, pharmaceutical companies would no longer be legally allowed to fast-track their billion-dollar vaccines to market under Emergency Use Authorization

Only Green Med Info, a health news and information site, saw through the chicanery: “A Media Smear Campaign Timed to Clear Market for Pfizer’s Ivermectin Clone Drug,

But the RF rarely addressed the most important causes of death, notably infantile diarrhea and tuberculosis, for which technical fixes were not then available and which demanded long-term, socially oriented investments, such as improved housing, clean water, and sanitation systems. The RF avoided disease campaigns that might be costly, complex, or time-consuming (other than yellow fever, which imperiled [the military, and] commerce). Most campaigns were narrowly construed so that quantifiable targets (insecticide spraying or medication distribution, for example) could be set, met, and counted as successes, then presented in business-style quarterly reports. In the process, RF public health efforts stimulated economic productivity, expanded consumer markets, and prepared vast regions for foreign investment and incorporation into the expanding system of global capitalism.

The combined Gates/Fauci power to rain foreign aid dollars on capital-starved African governments made them modern imperial viceroys on the continent. WHO became their colonial vassal, legitimizing and facilitating their campaigns to open African markets for drugmakers to dump unwanted products and to experiment with promising new cures.

Nevertheless, WHO—which, as we shall soon see, was by then under the control of Bill Gates and Anthony Fauci—began shipping this lethal concoction to developing nations globally to use on their pregnant women.35 “It’s a mystery why Nevirapine was ever developed, launched or marketed to the developing world the way it was,” says journalist Celia Farber, “since it was rejected by every Western drug safety agency—every single time. Why was it then re-purposed and shipped to non-Westerners?

Thus, if any FDA-approved drug like hydroxychloroquine (or ivermectin) proved effective against COVID, pharmaceutical companies would no longer be legally allowed to fast-track their billion-dollar vaccines to market under Emergency Use Authorization. Instead, vaccines would have to endure the years-long delays that have always accompanied methodical safety and efficacy testing, and that would mean less profits,

During the Cold War, the US military and intelligence agencies largely replaced Europe’s colonial armies in those regions, supporting virtually any tinhorn dictator who proved his “anti-Communist” bona fides by rolling out red carpets for US multinationals. When the Berlin Wall fell, the United States already had 655 military bases (now 800)80 across the developing world, and US companies had blank checks in host nations to extract agricultural, mineral, petroleum, and lumber resources, and large markets for finished goods including, notably, pharmaceuticals

Gates’s contraceptive of choice is the long-term infertility agent Depo-Provera. Population planners have administered Depo-Provera primarily to poor and Black women in the United States since its invention in 1967. In the United States, 84 percent of Depo-Provera users are Black, and 74 percent are low-income.70 Depo-Provera’s biggest promoter, Planned Parenthood, specifically targets Blacks71 and Latinas72 in its marketing campaigns.

From the outset, hydroxychloroquine (HCQ) and other therapeutics posed an existential threat to Dr. Fauci and Bill Gates’ $48 billion COVID vaccine project, and particularly to their vanity drug remdesivir, in which Gates has a large stake.1 Under federal law, new vaccines and medicines cannot quality for Emergency Use Authorization (EUA) if any existing FDA-approved drug proves effective against the same malady: For FDA to issue an EUA (emergency use authorization), there must be no adequate, approved, and available alternative to the candidate product for diagnosing, preventing, or treating the disease or condition. . . .2 Thus, if any FDA-approved drug like hydroxychloroquine (or ivermectin) proved effective against COVID, pharmaceutical companies would no longer be legally allowed to fast-track their billion-dollar vaccines to market under Emergency Use Authorization. Instead, vaccines would have to endure the years-long delays that have always accompanied methodical safety and efficacy testing, and that would mean less profits, more uncertainty, longer runways to market, and a disappointing end to the lucrative COVID-19 vaccine gold rush. Dr. Fauci has invested $6 billion in taxpayer lucre in the Moderna vaccine alone.3 His agency is co-owner4 of the patent and stands to collect a fortune in royalties. At least four of Fauci’s hand-picked deputies are in line to collect royalties of $150,000/year based on Moderna’s success, and that’s on top of the salaries already paid by the American public.5,6

Under federal law, new vaccines and medicines cannot quality for Emergency Use Authorization (EUA) if any existing FDA-approved drug proves effective against the same malady: For FDA to issue an EUA (emergency use authorization), there must be no adequate, approved, and available alternative to the candidate product for diagnosing, preventing, or treating the disease or condition. . . .2 Thus, if any FDA-approved drug like hydroxychloroquine (or ivermectin) proved effective against COVID, pharmaceutical companies would no longer be legally allowed to fast-track their billion-dollar vaccines to market under Emergency Use Authorization. Instead, vaccines would have to endure the years-long delays that have always accompanied methodical safety and efficacy testing, and that would mean less profits, more uncertainty, longer runways to market, and a disappointing end to the lucrative COVID-19 vaccine gold rush. Dr. Fauci has invested $6 billion in taxpayer lucre in the Moderna vaccine alone.3 His agency is co-owner4 of the patent and stands to collect a fortune in royalties. At least four of Fauci’s hand-picked deputies are in line to collect royalties of $150,000/year based on Moderna’s success, and that’s on top of the salaries already paid by the American public.5

The headline of a comprehensive exposé in The Guardian expressed the global shock among the scientific community at the rank corruption by scientific publishing’s most formidable pillars: “The Lancet has made one of the biggest retractions in modern history. How could this happen?”94 The Guardian writers openly accused The Lancet of promoting fraud: “The sheer number and magnitude of the things that went wrong or missing are too enormous to attribute to mere incompetence.” The Guardian commented, “What’s incredible is that the editors of these esteemed journals still have a job—that is how utterly incredible the supposed data underlying the studies was.” The capacity of their Pharma overlords to strong-arm the world’s top two medical journals, the NEJM and The Lancet, into condoning deadly research95,96 and to simultaneously publish blatantly fraudulent articles in the middle of a pandemic, attests to the cartel’s breathtaking power and ruthlessness. It is no longer controversial to acknowledge that drug makers rigorously control medical publishing and that The Lancet, NEJM, and JAMA are utterly corrupted instruments of Pharma. The Lancet editor, Richard Horton, confirms, “Journals have devolved into information laundering operations for the pharmaceutical industry.”97 Dr. Marcia Angell, who served as an NEJM editor for 20 years, says journals are “primarily a marketing machine.”98 Pharma, she says, has co-opted “every institution that might stand in its way.”99,100 Cracking Down on HCQ to Keep Case Fatalities High Referring to the Lancet Surgisphere study during a May 27 CNN interview, Dr. Fauci stated on CNN about hydroxychloroquine,

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Instead, vaccines would have to endure the years-long delays that have always accompanied methodical safety and efficacy testing, and that would mean less profits, more uncertainty, longer runways to market, and a disappointing end to the lucrative COVID-19 vaccine gold rush. Dr. Fauci has invested $6 billion in taxpayer lucre in the Moderna vaccine alone.3 His agency is co-owner4 of the patent and stands to collect a fortune in royalties. At least four of Fauci’s hand-picked deputies are in line to collect royalties of $150,000/year based on Moderna’s success, and that’s on top of the salaries already paid by the American public.5,6

And the real losers in that battle,” added Farber, “were the millions of African women and babies forced to take Nevirapine, a drug that does not prevent AIDS but sickens and kills people who take it.” In the end, Dr. Fauci succeeded in rigging corrupt clinical trials, concealing catastrophic cheating, and deftly manipulating the politics to bring his dangerous and inefficacious drug, Nevirapine, to market.

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Once the product gets to market, the pharmaceutical company pays royalties—a form of legalized kickbacks—through an informal scheme that allows Pharma to funnel its profits from drug sales to NIAID and to the NIAID officials who worked on the product. Under a secretive, unpromulgated HHS policy, Dr. Fauci and his NIAID underlings may personally pocket up to $150,000 annually from drugs they helped develop at taxpayers’ expense

Fear is a market. To instill fear in people also has advantages. Not only in terms of drug use. Anxiety-driven people are easier to rule.” —Gerd Gogerenzer, Director Emeritus at the Max Planck Institute for Educational Research (Torsten Engelbrecht, Virus Mania, 2021)

Billionaires have had a terrific pandemic. Central banks pumped trillions of dollars into financial markets to save the economy, yet much of that has ended up lining the pockets of billionaires riding a stock market boom. Vaccines were meant to end this pandemic, yet rich governments allowed pharma billionaires and monopolies to cut off the supply to billions of people. The result is that every kind of inequality imaginable risks rising. The predictability of it is sickening. The consequences of it kill.

Fourteen Ways To Tame Pharma 1. No more direct-to-consumer advertising on TV, in magazines, or on the internet 2. No more drug company-sponsored junkets, dinners, promotional gifts, or continuing medical education for doctors or medical students 3. No more financial support for medical professional organizations 4. No more beautiful salespeople congregating in the doctors' waiting room 5. No more free samples 6. No more off-label marketing 7. No more co-opting of thought leaders 8. No more drug company funding for the Food and Drug Administration 9. Bigger fines and criminal penalties for malfeasance that are directed against the executives as well as the companies 10. Shortened patent protection for companies that break the law 11. No more financial aid for consumer advocacy groups 12. No more disease-awareness campaigns 13. No more unlimited and undisclosed contributions to politicians 14. A three-year quarantine before politicians, staffers, and bureaucrats involved in setting or monitoring drug company regulations can join a drug company as officer or employee

Much of the increased prevalence of ADHD results from the “false positive” misidentification of kids who would be better off never receiving a diagnosis. Drug company marketing pressure often leads to unnecessary treatment with medications that can cause the harmful side effects of insomnia, loss of appetite, irritability, heart rhythm problems, and a variety of psychiatric symptoms.

Others argue that an increasingly demanding society is exposing previously subclinical ADHD symptoms. As performance standards are ratcheted up and external stimulation becomes nonstop and blaring, previously well-adapted individuals with mild ADHD may now be reaching a clinically significant level of impairment that qualifies as a mental disorder and requires treatment. My point back is that the difficulties people have in meeting society's expectations should not all be labeled as mental disorders. [...] If we, as a society, choose to help people enhance their performance to meet (perhaps excessive) demands, this should be an open policy decision - not one cloaked under medical auspices, done by medical prescription, and enhanced by drug company marketing.

The FDA allows big Pharma to falsify the studies required to patent drugs. These corporations hire armies of ghostwriters to stuff websites and medical journal articles with marketing lies. Finding the truth is now nearly impossible. But all this gets overlooked as the companies pay billions of dollars in criminal settlements nearly every year.

Henrique Dubugras, the co-founder of Brex, told me he was most excited about companies focused on rebuilding insurance. Mario Schlosser, the co-founder of Oscar Health, pointed to the wealth of opportunities still left to revamp healthcare. Max Mullen, who co-founded Instacart, raved about the future of food; Max Levchin of Affirm and PayPal talked about the importance of “clean water, access to food, climate change, and improvement in education.” For Neha Narkhede of Confluent, it was “the consumerization of the enterprise,” meaning a bottom-up adoption of tools to make enterprise sales happen. Michelle Zatlyn, the co-founder of Cloudflare, was excited about the future of social networks. And on the life science and healthcare side, Arie Belldegrun of Kite Pharma was excited about cell therapy, while Nat Turner of Flatiron Health was keen on the application of data in “neurology, neurodegenerative disease, and cardiovascular diseases.” The most interesting response came from Tony Fadell, the co-founder of Nest. “I think it’s more important to look at the markets than spaces and industries,” he told me. Beyond Silicon Valley, big changes are happening in India, in Southeast Asia, and across Latin America. “These places are going through massive transitions, just like China has already. You need to pay attention to these new markets and see what unique problems you can solve for these markets. You always need to think in the context of the problems of the place you’re going after.

Pfizer’s clinical data predicted potentially fatal myocarditis in one in every 318 teens. Post-marketing data confirm astronomically high rates of myocarditis injuries.

In medicine, brand identities are irrelevant, and there’s a factual, objective answer to whether one drug is the most likely to improve a patient’s pain, suffering and longevity. Marketing, therefore, one might argue, exists for no reason other than to pervert evidence-based decision-making in medicine. This is a very powerful machine: tens of billions of pounds are spent each year, as much as $60 billion in the US alone, on medicines marketing.3 And, most impressively, this money isn’t plucked from the air: it is paid for by patients, funded entirely from the public purse, or patients’ payments into medical insurance companies. About a quarter of the money taken by pharmaceutical companies for the drugs they sell is turned around into promotional activity which has, as we will see, a provable impact on doctors’ prescribing. So we pay for products, with a huge uplift in price to cover their marketing budget, and that money is then spent on distorting evidence-based practice, which in turn makes our decisions unnecessarily expensive, and less effective.

Doctors and Big Pharma prepared the battlefield...creating a market for the cartels, who then jumped at the opportunity to own the supply and feed the demand.