Overdose Quotes

There are some days when I think I'm going to die from an overdose of satisfaction.

Books are a hard-bound drug with no danger of an overdose. I am the happy victim of books.

Books are a hard-bound drug with no danger of an overdose. I am the happy victim of books.

Imagine 4 years. Four years, two suicides, one death, one rape, two pregnancies (one abortion), three overdoses, countless drunken antics, pantsings, spilled food, theft, fights, broken limbs, turf wars–every day, a turf war–six months until graduation and no one gets a medal when they get out. But everything you do here counts. High school.

Have you made any plans? Take an overdose, slash my wrists then hang myself. All those things together? It couldn't possibly be misconstrued as a cry for help.

Dennis Hutch had stepped up into the top seat when its founder had died of a lethal overdose of brick wall, taken while under the influence of a Ferrari and a bottle of tequila.

I'm still not sure I didn't hallucinate the conversation while overdosing on his pheromones.

I’d spent my entire life overdosing on uncut escapism, willingly allowing fantasy to become my reality.

Girls are always saying things like, “I’m so unhappy that I’m going to overdose on aspirin,” but they’d be awfully surprised if they succeeded. They have no intention of dying. At the first sight of blood, they panic.

He talks pretty big for a gutter wizard," he muttered. "You don't understand at all," said the wizard wearily. "I'm so scared of you my spine has turned to jelly, it's just that I'm suffering from an overdose of terror right now. I mean, when I've got over that then I'll have time to be decently frightened of you.

People are fragile. They die of mistakes, of overdoses, of sickness. But mostly they die of Death.

Excuse me, I feel interrupted and I think I've overdose from the idea of loving you.

Love is the only drug that's healthy to overdose on.

What kills a person at twenty-five? Leukemia. An accident. But George knows the better odds are that someone who passes at that age dies of unhappiness. Drug overdose. Suicide. Reckless behavior.

I see you overdosed on vitamin bitch today,

Five truly effective prescriptions to remedy a bad day. (You can't overdose.) —Pray; discuss your troubles with God. —List your blessings. (The blue sky, soft cookies, warm socks, etc.) —Call your mom. —Visit an animal shelter and hug a lonely cat. —Visit a nursing home and hug a lonely grandparent.

When the bell of my flat rings at four o’clock in the afternoon, I don’t expect a policeman to be standing outside. “Sorry to disturb you sir,” he says. “Detective sergeant McCorquodale. It’s about your mother.” Detective sergeant McCorquodale is an enormous lighthouse of a man with the untroubled skin of a baby and not a trace of facial hair; a sort of man-boy who’s overdosed on growth hormones.

You are my drug of choice, and I plan to overdose.

Yeah. Just keep the live feed going so that I can see it and pretend I’m there, too. (Tory) Yes, my queen. Anything else you’d like? (Geary) A million dollars and Brad Pitt. (Tory) You forgot world peace. (Geary) I’m feeling a bit selfish today. Teenage hormonal overdose, I think. Or just general excitement. (Tory)

Most parents try really hard to give their kids the best possible life. They give them the best food and clothes they can afford, take their own kind of take on training kids to be honest and polite. But what they don't realize is no matter how much they try, their kids will get out there. Out to this complicated little world. If they are lucky they will survive, through backstabbers, broken hearts, failures and all the kinds of invisible insane pressures out there. But most kids get lost in them. They will get caught up in all kinds of bubbles. Trouble bubbles. Bubbles that continuously tell them that they are not good enough. Bubbles that get them carried away with what they think is love, give them broken hearts. Bubbles that will blur the rest of the world to them, make them feel like that is it, that they've reached the end. Sometimes, even the really smart kids, make stupid decisions. They lose control. Parents need to realize that the world is getting complicated every second of every day. With new problems, new diseases, new habits. They have to realize the vast probability of their kids being victims of this age, this complicated era. Your kids could be exposed to problems that no kind of therapy can help. Your kids could be brainwashed by themselves to believe in insane theories that drive them crazy. Most kids will go through this stage. The lucky ones will understand. They will grow out of them. The unlucky ones will live in these problems. Grow in them and never move forward. They will cut themselves, overdose on drugs, take up excessive drinking and smoking, for the slightest problems in their lives. You can't blame these kids for not being thankful or satisfied with what they have. Their mentality eludes them from the reality.

I don't like to overdose. Call me old-fashioned.

Empathy is wonderful, but you can still overdose on it if you try too much to fast.

Every night, in every Coldtown, people die. People are fragile. They die of mistakes, of overdoses, of sickness. But mostly they die of Death.

People die all around us all the time. Drop like flies. Overdose. Aids. Sometimes they kill themselves. People come. They go. Dying is the same as rehab or moving back to Missouri. It just means I won't be seeing them again

I now realize that education is a last wild effort on the part of the authorities to prevent an overdose of leisure from driving the world mad. Learning is no longer an improver; it is merely the most expensive time-filler the world has ever known.

Vincent Van Gogh used to eat yellow paint because he thought it would get the happiness inside him. Many people thought he was mad and stupid for doing so because the paint was toxic, never mind that it was obvious that eating paint couldn't possibly have any direct correlation to one's happiness, but i never saw that. If you were so unhappy that even the maddest ideas could possibly work, like painting the walls of your internal organs yellow, then you are going to do it. It's really no different than falling in love or taking drugs. There is a greater risk of getting your heart broken or overdosing, but people still do ir everyday because there was always that chance it could make things better. Everyone has their own yellow paint.

Why do I take a blade and slash my arms? Why do I drink myself into a stupor? Why do I swallow bottles of pills and end up in A&E having my stomach pumped? Am I seeking attention? Showing off? The pain of the cuts releases the mental pain of the memories, but the pain of healing lasts weeks. After every self-harming or overdosing incident I run the risk of being sectioned and returned to a psychiatric institution, a harrowing prospect I would not recommend to anyone. So, why do I do it? I don't. If I had power over the alters, I'd stop them. I don't have that power. When they are out, they're out. I experience blank spells and lose time, consciousness, dignity. If I, Alice Jamieson, wanted attention, I would have completed my PhD and started to climb the academic career ladder. Flaunting the label 'doctor' is more attention-grabbing that lying drained of hope in hospital with steri-strips up your arms and the vile taste of liquid charcoal absorbing the chemicals in your stomach. In most things we do, we anticipate some reward or payment. We study for status and to get better jobs; we work for money; our children are little mirrors of our social standing; the charity donation and trip to Oxfam make us feel good. Every kindness carries the potential gift of a responding kindness: you reap what you sow. There is no advantage in my harming myself; no reason for me to invent delusional memories of incest and ritual abuse. There is nothing to be gained in an A&E department.

Melancholy Baby dies from an overdose of time

Grace was my drug of choice, and tonight the dealer was giving out hits for free. I'd stay until I overdosed.

On need of supplement & vitamins- "If you eat a balanced diet you get all the vitamins and minerals you need and you don’t need any supplement and overdosing can actually be more harmful.

If love is a form of substance abuse, I hope to die high.

You can't overdose on friends, only enemies.

i hate telling people how it happened. there is a difference between fact & truth. the fact is that she overdosed. the truth is that he killed her.

I am both numb and oversensitive, overwhelmed by the need, the raw and desperate need of the girls I am listening to and trying to help. I'm overdosing on the trauma of others, while still barely healing from my own. I cry for hour at home and have fitful nights of little sleep. My nightmares resurface as my own pain is repeated to me, magnified a thousand times. It feels insurmountable. How can you save everyone? How can you rescue them? How do you get over your pain? How do you ever feel normal?

The good news is that by the second year, those cravings were about as half as frequent, and by the third year, half as much again. I'm still a little bent, a little crooked, but all things crooked, I can't complain. After all those years of all kinds of abuse and crashing into trees at eighty miles an hour and jumping off buildings and living through overdoses and liver disease, I feel better now than I did ten years ago. I might have some scar tissue, but that's alright, I'm still making progress.

Carved deep into my veins but didn't bleed Overdosed on sleeping pills but didn't sleep When your heart is heavy, it gets increasingly harder to breathe Clearly there's a God But why has he forsaken me?

There have been times I've felt so much art in my soul I grew sick of artists.

You want to start some shit, boy? Let’s go outside. (Devyn) Oh, good. I’m just in time for another round of Grand Testosterone Overdose. Ooooh, Alix, Claira…anyone got popcorn? Or maybe I should get Taryn? Then we could insult his manhood and watch him pop a gasket, too. (Zarina)

When I was younger, I would cling to life because life was at the top of the turning wheel. But like the song of my gypsy girl, the great wheel turns over and lands on a minor key. It is then that you come of age and life means nothing to you. To live, to die, to overdose, to fall in a coma in the street... it is all the same. It is only in the peach innocence of youth that life is at its crest on top of the wheel. And there being only life, the young cling to it, they fear death… And they should! ...For they are 'in' life.

Here is The Boy with the Thorn in His Side, dying in your world. A man made monster with every human emotion, overdosed on worthlessness in a world that could never wrap it’s head around him (so don’t even try). When it’s all over just remember every single word you ever said was always just a bullet to his head. Bury him underground between friends and love - the only things that are gonna make it to the end with him. Look for his body buried beneath where the yellow weeds are growing and know he’s still living in his nightmares.

2008:  Drug overdoses, mostly from opiates, surpass auto fatalities as leading cause of accidental death in the United States.

I thought over and over about what I was going to do when Carly overdosed and died. How would we go on? And then I knew: I wouldn’t go on. And then I realized that it was just going to be too painful to actually have to watch her die. Right in front of me. My daughter was dying. That’s when I snapped.

Unreason is an essential medicine as long as you do not overdose.

Nature full strength is more than we can take, Adam One used to say. It's a potent hallucinogen, a soporific, for the untrained Soul. We're no longer at home in it. We need to dilute it. We can't drink it straight. And God is the same. Too much God and you overdose. God needs to be filtered.

You can't figure out why I'm mad? How about because I had my tongue between your legs two days ago, or the fact we both almost overdosed on orgasms, or maybe it's because I got a fucking hard on the minute you walked in that conference room door? Take your pick... there are a variety of reasons why I'm mad.

The truth is that all this was just part of the suicide process. Because tanning and steroids are only a problem if you plan to live a long time. Because the only difference between a suicide and a martyrdom really is the amount of press coverage. If a tress falls in the forest and nobody is there to hear it, doesn’t it just lie there and rot? And if Christ had died from a barbiturate overdose, alone on the bathroom floor, would He be in Heaven This wasn’t a question of whether I was going to kill myself. This, this effort, this money and time, the writing team, the drugs, the diet, the agent, the flights of stairs going up to nowhere, all this was so I could off myself with everyone’s full attention.

Before capitalism will go to hell, then, it will for the foreseeable future hang in limbo, dead or about to die from an overdose of itself but still very much around, as nobody will have the power to move its decaying body out of the way.

I don’t understand suicide,” Neil said. “Staying alive has always been so important I can’t imagine actively trying to die.” “He wasn’t,” Andrew said, like Neil was being stupid. […] “He wanted a way out for a little while, a few hours where he didn’t have to think or feel. Problem was he picked an out that’s easy to die on. That’s his fault.

The religious school she went to, growing up, Ms. Wright said how all the girls had to wear a scarf tied to cover their ears at all times. Based on the biblical idea that the Virgin Mary became pregnant when the Holy Spirit whispered in her ear. The idea that ears were vaginas. That, hearing just one wrong idea, you lost your innocence. One detail too many and you’d be ruined. Overdosed on information.

Borderline means you’re one of those girls… …who walk around wearing long sleeves in the summer because you’ve carved up your forearms over your boyfriend. You make pathetic suicidal gestures and write bad poetry about them, listen to Ani DiFranco albums on endless repeat, end up in the emergency room for overdoses, scare off boyfriends by insisting they tell you that they love you five hundred times a day and hacking into their email to make sure they’re not lying, have a police record for shoplifting, and your tooth enamel is eroded from purging. You’ve had five addresses and eight jobs in three years, your friends are avoiding your phone calls, you’re questioning your sexuality, and the credit card companies are after you. It took a lot of years to admit that I was exactly that girl, and that the diagnostic criteria for the disorder were essentially an outline of my life.

So that's it. That's the big secret. I tried to kill myself on New Year's eve. Just like Sadie did last night. Only she really did it. I don't know all the detatils, just the basics. She took a bunch of pills. I don't know what they were or where she got them. I'd like to think they were Wonder Drug. Then at least she could have gone thinking she was flying.

And if Christ had died from a barbiturate overdose, alone on the bathroom floor, would he be in heaven?

Books are a hard-bound drug with no danger of an overdose i'm the happy victim of books

We tend to die, women who’ve been through the fire. Sometimes we choose obvious ways, suicide and overdoses; sometimes we’re more subtle, marrying someone who likes to use his fists, or we drink too much and keep getting behind the wheel until we run out of luck.

When I was younger, I would cling to life because life was at the top of the turning wheel. But like the song of my gypsy-girl, the great wheel turns over and lands on a minor key. It is then that you come of age and life means nothing to you. To live, to die, to overdose, to fall in a coma in the street... it is all the same. It is only in the peach innocence of youth that life is at its crest on top of the wheel. And there being only life, the young cling to it, they fear death... And they should! ...For they are in life.

According to the Centers for Disease Control and Prevention, in the quarter century following the introduction of OxyContin, some 450,000 Americans had died of opioid-related overdoses. Such overdoses were now the leading cause of accidental death in America, accounting for more deaths than car accidents—more deaths, even, than that most quintessentially American of metrics, gunshot wounds. In fact, more Americans had lost their lives from opioid overdoses than had died in all of the wars the country had fought since World War II.

May you have all the pleasure you've always craved. Nay, may you drown in it!

The number of Ohioans dead from drug overdoses between 2003 and 2008 was 50 percent higher than the number of U.S. soldiers who died in the entire Iraq War.

Drug overdoses passed fatal vehicle accidents nationwide for the first time in 2008.

An overdose of insulin would be the easiest, cleanest route—especially since he keeps his meter and pens in the top right drawer of his desk, unprotected.

Loose diagnosis is causing a national drug overdose of medication. Six percent of our people are addicted to prescription drugs, and there are now more emergency room visits and deaths due to legal prescription drugs than to illegal street drugs.6

She is in my heart and in my bones; she is in the very depths of my being. She is my overdose, my addiction so deep that it cannot be destroyed without killing the addict too. Her face was my sun and her eyes were my stars and she is in my thoughts every minute of every day. There are a million guys out there who would have given anything for a shot at bringing her happiness, so I hope that for the short time that we had together, I at least made her as happy as she made me. I loved her so much and I'll always love her. Till the end of the world and beyond.

Ethan Nadelmann, one of the leading drug reformers in the United States, had explained: "People overdose because [under prohibition] they don't know if the heroin is 1 percent or 40 percent...Just imagine if every time you picked up a bottle of wine, you didn't know whether it was 8 percent alcohol or 80 percent alcohol [or] if every time you took an aspirin, you didn't know if it was 5 milligrams or 500 milligrams.

Welcome each day like a good meal. The essence of a life well digested comes from knowing your strengths, overdosing on the senses and remaining active and playful. Keep you hands on the plow, push don't ever stop pushing always be willing to give a little more energy-the tension may always be there. Then your life will never go limp

Overdose deaths involving opiates rose from ten a day in 1999 to one every half hour by 2012. Abuse of prescription painkillers was behind 488,000 emergency room visits in 2011, almost triple the number of seven years before.

I realised from quite early on in my childhood that I saw things differently from other people,' he wrote. 'But, more than not, it's helped me in my life. Psychopathy(if that's what you call it) is like a medicine for modern times. If you take it in moderation it can prove extremely beneficial. It can alleviate a lot of existential ailments that we would otherwise fall victim to because our fragile psychological immune systems just aren't up to the job of protecting us. But if you take too much of it, if you overdose on it, then there can, as is the case with all medicines, be some rather unpleasant side effects.

Prohibition kills, education saves lives

When the constellation of Cassiopeia is in this hemisphere and I am able to identify it, I feel less alone. This isn't a reasoned response to a configuration of stars, but the heart cannot flourish on logic alone. Unreason is an essential medicine as long as you do not overdose.

Parents need to realize that the world is getting complicated every second. With new problems, new diseases, new habits. They have to realize the vast probability of their kids being victims of this age, this complicated era. Your kids could be exposed to problems that no kind of therapy can help. Your kids could be brainwashed by themselves to believe in insane theories that drive them crazy. Most kids will go through this stage. The lucky ones will understand. They will grow out of them. The most unlucky ones will live in these problems. Grow in them and never move forward. They will cut themselves, overdose on drugs, take up excessive drinking and smoking, for the slightest problems in their lives. You can't blame these kids for not being thankful or satisfied with what they have. Their mentality eludes them from the reality.

[S]he takes a killer. Sometimes she takes two, never more than two, because some things are good for us but too much is suddenly bad.

Laughter IS the BEST medicine! It’s FREE! You can overdose on it! It helps you embrace the insanities of life! It reduces stress, heals your body and relieves pain! It fights disease and cancer and strengthens the immune system! It eases your mind, it protects your heart and soothes your soul!

Government agencies are trying to get doctors to cut back on prescribing opioids. I understand that they need to do something about the epidemic of overdoses. However, labeling everyone as addicts, including those who responsibly take opioids for chronic pain, is not the answer. If the proposed changes take effect, they would force physicians to neglect their patients. Moreover, legitimate pain patients, like myself, would be left in agony on a daily basis.

At the end of his life, which had included financial ruin in the Great Depression, his wife's barbiturate addiction and death by overdose, and then his own lung cancer, Doc said, "It was enough to have been a unicorn." What he meant was that he got to do art. It was magic to him that his hands and mind got to make wonderful things, that he didn't have to be just another goat or horse.

I thought maybe, just maybe, I could overdose on him. If I could just take him one more time, and shut my eyes, and it would be the last time, with anyone, with anything, that would be alright. Guilt would be gone. Hurt would be gone. Confusion would be gone. Oppression would be gone. Obsession would be gone.

Dodger,” he whispers. “Don’t die. This is an order. This is a command. This is an adjuration. Do whatever you have to do, break whatever you have to break, but don’t you die. This is an order. This is—” This is her eyes opening, pupils reduced to black pinpricks against the gray of her irises, until she looks like she’s suffered a massive opiate overdose. This is gold sparking in the gray, brief and bright, as the Impossible City tries to call her home. He feels the gold in his own bones respond, reaching for the gold in Dodger’s, yearning to reunite.

I wonder if we are seeing a return to the object in the science-based museum. Since any visitor can go to a film like Jurassic Park and see dinosaurs reawakened more graphically than any museum could emulate, maybe a museum should be the place to have an encounter with the bony truth. Maybe some children have overdosed on simulations on their computers at home and just want to see something solid--a fact of life.

Drug overdose had already taken the lives of 300,000 Americans over the past fifteen years, and experts now predicted that 300,000 more would die in only the next five. It is now the leading cause of death for Americans under the age of fifty, killing more people than guns or car accidents, at a rate higher than the HIV epidemic at its peak.

Was Trakl a Christian? Yes, of course, at times he becomes a Christian, among a general confusion of becomings—becoming an animal, becoming a virus, becoming inorganic—just as he was also an antichrist, a poet, a pharmacist, an alcoholic, a drug addict, a psychotic, a leper, a suicide, an incestuous cannibal, a necrophiliac, a rodent, a vampire, and a werewolf. Just as he became his sister, and also a hermaphrodite. Trakl's texts are scrawled over by redemptionist monotheism, just as they are stained by narcotic fluidities, gnawed by rats, cratered by Russian artillery, charred and pitted by astronomical debris. Trakl was a Christian and an atheist and also a Satanist, when he wasn't simply undead, or in some other way inhuman. It is perhaps more precise to say that Trakl never existed, except as a battlefield, a reservoir of disease, the graveyard of a deconsecrated church, as something expiring from a massive cocaine overdose on the floor of a military hospital, cheated by lucidity by the searing onslaught of base difference.

So many people died last year: the accidental overdose, the car wreck in East Hampton, the surprise illness. People just disappeared. I fall asleep to the music coming from the Abbey, a song from the past, “Hungry Like the Wolf,” rising faintly above the leaping chatter of the club, transporting me for one long moment into someone both young and old. Sadness: it’s everywhere.

One way to say all this is, Our mother was an addict and she overdosed. Another way is, Our mother was suicidal and she killed herself. Another way is, Our mother was poor and ignored and dismissed for years by doctors who put her on legal and extremely profitable heroin, which eventually killed her. Another way is, Our mother needed help and no one, including us, gave it to her.

In 1955, amid the great fanfare that accompanied the initial release of the [polio] vaccine, Dr. Jonas Salk was asked who owned the patent. He replied, "Well, the people, I would say. Could you patent the sun?

Often on the menu, oysters will be listed as “oysters on the half shell.” As opposed to what? “In a Kleenex?” Even the way you are supposed to eat an oyster indicates something counterintuitive. “Squeeze some lemon on it, a dab of hot sauce, throw the oyster down the back of your throat, take a shot of vodka, and try to forget you just ate snot from a rock.” That is not how you eat something. That is how you overdose on sleeping pills.

While Apicius is full of ancient delicacies such as roasted peacock, boiled sow vulva, testicles, and other foods we would not commonly eat today, there are many others that are still popular, including tapenade, absinthe, flatbreads, and meatballs. There is even a recipe for Roman milk and egg bread that is identical to what we call French toast. And, contrary to popular belief, foie gras was not originally a French delicacy. The dish dates back twenty-five hundred years, and Pliny credits Apicius with developing a version using pigs instead of geese by feeding hogs dried figs and giving them an overdose of mulsum (honey wine) before slaughtering them.

What do you think he saw?" Damn--I regret the awed way I phrased that and the hushed voice I used. As if I think acid is a "religious" experience, a visionary thing. "Himself," Josh says. "You always see your true self on acid. You just usually see more than you want to see. So it all seems disorted." See what I mean? He's not your normal stoner. The guy should become a poet, a psychologist, a scientist. We pull up near Greg's house and stare at it like it's a damn fortress. "You don't think he needs to go to the hospital?" I ask. "Nope," Josh says. "For a while, I thought maybe, yeah. But he's good now, he's off it, he's not hallucinating anymore." "You're sure?" "Yeah." "'Cuz you can die on LSD-" "That's such anti-drug propaganda bullshit, Dan," Josh interrupts. "Nobody's ever died from an LSD overdose. Ever. As long as you keep people from doing stupid things while they're tripping, it's all good man, man. Why do you think I babysat him?" He reaches into the backseat and punches my shoulder. "LSD isn't your dad's smack. So stop worrying." I scrunch down in the seat. How'd he know about that? "Right. What's the plan?" "I'd ask him if ther was a key hidden under a rock," Josh says, "but he's not gonna be much help. Watch." He pokes Greg in the leg, prods him on the shoulder, grabs his cheeks and smushes them together, the way parents do to a baby, and says, " Ootchi googi Greggy, did ums have a good trippy? Did ums find out itty-bitty singies about oos-self zat oos didn't likeums?" Yup... Greg was in his own little world...

Side effects of those very same prescription drugs are the third leading cause of death, behind heart disease and cancer. That’s right! Prescription drugs kill more people than traffic accidents. According to Dr. Barbara Starfield, writing in the Journal of the American Medical Association in 2000, “adverse effects of medications” (from drugs that were correctly prescribed and taken) kill 106,000 people per year.5 And that doesn’t include accidental overdoses.

There were leaders here and elsewhere who agreed with the woman, he knew, including an Ohio sheriff who'd recently proposed taking naloxone away from his deputies, claiming that repeated overdose reversals were "sucking the taxpayers dry." Lloyd thought immediately of the answer Jesus gave when his disciple asked him to enumerate the concept of forgiveness. Should it be granted seven times, Peter wanted to know, or should a sinner be forgiven as many as seventy times? In the shadow of the church steeples, Lloyd let Jesus answer the woman's question: "Seventy times seven," he said.

And as for what I’ve learned: be an instrument of peace. Be a gentleman at all costs. Enjoy yourself—have fun with your existence. Learn to listen to your inner voice and don’t overdose on yourself. Keep your darkness in check. Let music be a healing force. Be a real musician: once you start counting money before notes, you’re a full-time wannabe. Put your guitar down and go outside and take a long drink of light with your eyes. Go walk in the park and take off your shoes and socks and feel the grass under your feet and mud between your toes. Go see a baby smiling, go see a wino crawling, go see life. Feel life—all of it, as much as possible. Find a human melody, then write a song about it. Make it all come through your music.

The problem with today’s young people’, I said, ‘isn’t that they do things which are bad for them, as so much of the media likes to think. It’s that they don’t do these things right. You’re all so intent on getting off your heads on drugs that you don’t think about the fact that you could overdose and, to put it plainly, die. You drink until your liver explodes. You smoke until your lungs collapse beneath the rot. You create diseases which threaten to wipe you out. Have fun, by all means. Be debauched, it’s your duty. But be wise about it. All things in excess, but just know how to cope with them, that’s all I ask.

Children of the most privileged group in the wealthiest country in the history of the world were getting hooked and dying in almost epidemic numbers from substances meant to, of all things, numb pain. “What pain?” a South Carolina cop asked rhetorically one afternoon as we toured the fine neighborhoods south of Charlotte where he arrested kids for pills and heroin. Crime was at historic lows, drug overdose deaths at record highs. A happy façade covered a disturbing reality. I grew consumed by this story.

We're young. We’re supposed to drink too much. We're supposed to have bad attitudes and shag each other's brains out. We were designed to party. We owe it to ourselves to party hard. We owe it to each other. This is it. This is our time. So a few of us will overdose, or go mental. Charles Darwin said you can't make an omelet without breaking a few eggs. That's what it's about - breakin' eggs - by eggs, I mean, getting twatted on a cocktail of class. As. If you could see yourselves... We had it all. We have fucked up bigger and better than any generation that came before us. We were so beautiful... We're screw-ups. I plan on staying a screw-up until my late twenties, or maybe even my early thirties. And I will shag my own mum before I let anyone else take that away from me!

Like no other particle on earth, the morphine molecule seemed to possess heaven and hell. It allowed for modern surgery, saving and improving too many lives to count. It stunted and ended too many lives to count with addiction and overdose. Discussing it, you could invoke some of humankind’s greatest cultural creations and deepest questions: Faust, Dr. Jekyll and Mr. Hyde, discussions on the fundamental nature of man and human behavior, of free will and slavery, of God and evolution. Studying the molecule you naturally wandered into questions like, Can mankind achieve happiness without pain? Would that happiness even be worth it? Can we have it all?

This time of year is brutal. Joe knows exactly what Donny’s referring to. It’s January, just after the holiday season, a time for family and gift giving and celebration for most, a time of unbearable depression for others. The days are cold and dark by four thirty. Joe and Donny have responded to a lot of suicides over the years, and winter is sadly the most popular season. Joe won’t miss that part of his job. Discovering the bodies. Sometimes the body parts. A teenager overdoses on heroin. A mother swallows a bottle of prescription pills. A father leaps off the Tobin. A cop eats his gun.

President Obama came on the scene right as so many people in my community began to believe that the modern American meritocracy was not built for them. We know we’re not doing well. We see it every day: in the obituaries for teenage kids that conspicuously omit the cause of death (reading between the lines: overdose), in the deadbeats we watch our daughters waste their time with. Barack Obama strikes at the heart of our deepest insecurities. He is a good father while many of us aren’t. He wears suits to his job while we wear overalls, if we’re lucky enough to have a job at all. His wife tells us that we shouldn’t be feeding our children certain foods, and we hate her for it—not because we think she’s wrong but because we know she’s right. Many

The smell of cigarette smoke in the air in a tavern that changes names often, a bar cursed because of a girl who died of a drug overdose in the basement, we put a few coins in the jukebox; chose “Angel Band” by Johnny Cash and sat down at the bar, ordered a soda, you wanted a whiskey on the rocks. We saw the coal miner who moved here from West Virginia knocking back liquor like I drink sweet tea. No one asked why he was so solemn today. It was warm. It was relatively quiet. To anyone else, this place could feel sinister. But to us, it was freedom. It was a hiding place. No one was ever here long enough to know us. And we liked it that way.

Cannabis affects the brain because brain cells themselves produce cannabis-like neurotransmitters. The first such compound to be identified was christened anandamide, ananda being Sanskrit for “bliss.” The proteins that transmit anandamide’s message to the brain, the receptors, are mainly located in the striatum (hence the blissful feeling) and in the cerebellum (hence the unsteady gait after taking marijuana), in the cerebral cortex (hence the problems with association, the fragmented thoughts and confusion), and in the hippocampus (hence the memory impairment). But there are no receptors in the brain stem areas that regulate blood pressure and breathing. That’s why it’s impossible to take an overdose of cannabis, as opposed to opiates.

In 1988, a cave explorer named Véronique Le Guen volunteered for an extreme experiment: to live alone in an underground cavern in southern France without a clock for one hundred and eleven days, monitored by scientists who wished to study the human body's natural rhythms in the absence of time cues. For a while, she settled into a pattern of thirty hours awake and twenty hours asleep. She described herself as being "psychologically completely out of phase, where I no longer know what my values are or what is my purpose in life." When she returned to society, her husband later noted, she seemed to have an emptiness inside her that she was unable to fully express. "While I was alone in my cave I was my own judge," she said. "You are your own most severe judge. You must never lie or all is lost. The strongest sentiment I brought out of the cave is that in my life I will never tolerate lying." A little more than a year later, Le Guen swallowed an overdose of barbiturates and lay down in her car in Paris, a suicide at age thirty-three.

the Times says there's a heroin epidemic, Malone thinks, which is only an epidemic of course because now white people are dying. Whites started to get opium-based pills from their physicians: oxycodone, vicodin... But, it was expensive and doctors were reluctant to prescribe too much for exactly the fear of addiction. So the white folks went to the open market and the pills became a street drug. It was all very nice and civilized until the Sinoloa cartel down in Mexico made a corporate decision that it could undersell the big American pharmaceutical companies by raising production of its heroin thereby reducing price. As an incentive, they also increased its potency. The addicted white Americans found that Mexican ... heroin was cheaper and stronger than the pills, and started shooting it into their veins and overdosing. Malone literally saw it happening. He and his team busted more bridge-and-tunnel junkies, suburban housewives and upper Eastside madonnas than they could count....

Cheryl was aided in her search by the Internet. Each time she remembered a name that seemed to be important in her life, she tried to look up that person on the World Wide Web. The names and pictures Cheryl found were at once familiar and yet not part of her conscious memory: Dr. Sidney Gottlieb, Dr. Louis 'Jolly' West, Dr. Ewen Cameron, Dr. Martin Orne and others had information by and about them on the Web. Soon, she began looking up sites related to childhood incest and found that some of the survivor sites mentioned the same names, though in the context of experiments performed on small children. Again, some names were familiar. Then Cheryl began remembering what turned out to be triggers from old programmes. 'The song, "The Green, Green Grass of home" kept running through my mind. I remembered that my father sang it as well. It all made no sense until I remembered that the last line of the song tells of being buried six feet under that green, green grass. Suddenly, it came to me that this was a suicide programme of the government. 'I went crazy. I felt that my body would explode unless I released some of the pressure I felt within, so I grabbed a [pair ofl scissors and cut myself with the blade so I bled. In my distracted state, I was certain that the bleeding would let the pressure out. I didn't know Lynn had felt the same way years earlier. I just knew I had to do it Cheryl says. She had some barbiturates and other medicine in the house. 'One particularly despondent night, I took several pills. It wasn't exactly a suicide try, though the pills could have killed me. Instead, I kept thinking that I would give myself a fifty-fifty chance of waking up the next morning. Maybe the pills would kill me. Maybe the dose would not be lethal. It was all up to God. I began taking pills each night. Each-morning I kept awakening.

There is a particular kind of pain, elation, loneliness, and terror involved in this kind of madness. When you're high it's tremendous. The ideas and feelings are fast and frequent like shooting stars, and you follow them until you find better and brighter ones. Shyness goes, the right words and gestures are suddenly there, the power to captivate others a felt certainty. There are interests found in uninteresting people. Sensuality is pervasive and the desire to seduce and be seduced irresistible. Feelings of ease, intensity, power, well-being, financial omnipotence, and euphoria pervade one's marrow. But, somewhere, this changes. The fast ideas are far too fast, and there are far too many; overwhelming confusion replaces clarity. Memory goes. Humor and absorption on friends' faces are replaced by fear and concern. Everything previously moving with the grain is now against--you are irritable, angry, frightened, uncontrollable, and enmeshed totally in the blackest caves of the mind. You never knew these caves were there. It will never end, for madness carves its own reality. It goes on and on, and finally there are only others' recollections of your behavior--your bizarre, frenetic, aimless behaviors--for mania has at least some grace in partially obliterating memories. What then, after the medications, psychiatrist, despair, depression, and overdose? All those incredible feelings to sort through. Who is being to polite to say what? Who knows what? What did I do? Why? And most hauntingly, when will it happen again? Then, too, are the bitter reminders--medicine to take, resent, forget, take, resent, and forget, but always take....And always, when will it happen again? Which of my feelings are real? Which of the me's is me?

Did he want Nick to die on the floor of his bathroom from an overdose of mentholated rub? Did he want me to spend the last eighty years of my lifespan in a convent? Maybe he was mad that I was trying to sneak out of the house wearing his jeans for the third day in a row. "I am taking Doofus for another walk," I said clearly,daring him to defy me. "That would not be good for Doofus." Josh folded his arms. "Mom,that would not be good for Doofus." Oh! Dragging Mom into this was low.Not to mention Doofus. "Since when is going for a walk not good for a dog?" I challenged Josh. "He's an old dog," Josh protested. "He's four!" I pointed out. "That's twenty-eight in dog years! He's practically thirty!" "Strike!" Mom squealed amid the noise of electronic pins falling. Then she shook her game remote at both of us in turn. "I'm not stupid, you know.And I'm not as out of it as you assume. I know the two of you are really arguing about something else.It's those jeans again, isn't it?" She nodded to me. "I should cut them in half and give each of you a leg.Why does either of you want to wear jeans with 'boy toy' written across the seat anyway?" "I thought that was the fashion." Josh said. "Grandma wears a pair of sweatpants with 'hot mama' written across the ass." "That is different," Mom hissed. "She wears them around the kitchen." I sniffed indignantly. "I said," I announced, "I am goig for a walk with my dog. My beloved canine and I are taking a turn around our fair community. No activity could be more wholesome for a young girl and her pet. And if you have a problem with that,well! What is this world coming to? Come along, dear Doofus." I stuck my nose in the air and stalked past them, but the effect was lost. Somewhere around "our fair community," Mom and Josh both had lost interest and turned back to the TV. Or so I thought.But just as I was about to step outside,hosh appeared in the doorway between the kitchen and the mud room. "What the hell are you doing" he demanded. I said self-righteously, "I am taking my loyal canine for a w-" "You're going to Nick's,aren't you?" he whispered. "Do you think that's a good idea? I heard you yelled at him for no reason at the half-pipe,right before he busted ass.