Medical Lab Quotes

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One of the first things we teach medical students is to listen to the patient by taking a careful medical history. Ninety percent of the time, you can arrive at an uncannily accurate diagnosis by paying close attention, using physical examination and sophisticated lab test to confirm your hunch (and to increase the bill to the insurance company).
V.S. Ramachandran (The Tell-Tale Brain: A Neuroscientist's Quest for What Makes Us Human)
it is a federal system of sadistic torture, vivisection, and animal genocide, which has been carried on for decades under the fraudulent guise of respectable medical research. And nobody on the outside knows, or wants to know, or is willing to find out. My parents, my friends, my teachers, wouldnt listen to me, or suggested that if it was bothering me that much I just had to quit the job. Just like that. As if that would have solved anything. As if I could ever live with such cowardice. You can't imagine, or maybe you can, how many people are convinced - without knowing the first thing about it - Animal research is essential. Americans have been hopelessly brainwashed on this issue. The animal rights people, by and large, acknowledge the essential futility of trying to change the system. So they address the smaller issues, fighting for legislation which would provide one extra visit per week to the labs by a custodian of the US dept of agriculture. Or demanding that a squirrel monkey be given an extra 12 square inches in his holding pen, before being led to the slaughter. That sort of thing. For whomever, and whatever it's worth, I hope my little write up is clear. I dont have the guts to do whats necessary. I pray there's someone out there who does. God help all of us.
Michael Tobias (Rage and Reason)
For me, hands are hard." She looks up from what she's doing. "Because you're holding this disconnected hand, and it's holding you back." Cadavers occasionally effect a sort of accidental humanness that catches the medical professional off guard. I once spoke to an anatomy student who described a moment in the lab when she realized that the cadaver's arm was around her waist. It becomes difficult, under circumstances such as these, to retain one's clinical remove.
Mary Roach (Stiff: The Curious Lives of Human Cadavers)
Nelson-Rees had since been hired by the National Cancer Institute to help stop the contamination problem. He would become known as a vigilante who published “HeLa Hit Lists” in Science, listing any contaminated lines he found, along with the names of researchers who’d given him the cells. He didn’t warn researchers when he found that their cells had been contaminated with HeLa; he just published their names, the equivalent of having a scarlet H pasted on your lab door.
Rebecca Skloot (The Immortal Life of Henrietta Lacks)
The midpoint in medicine between excessive emotional involvement with patients and a complete lack of empathy is not a simple one to locate.
Christine Montross (Body of Work: Meditations on Mortality from the Human Anatomy Lab)
there is a photograph of zugibe and one of his volunteers in the aforementioned sindon article. zugibe is dressed in a knee-length white lab coat and is shown adjusting one of the vital sign leads affixed to the man's chest. the cross reaches almost to the ceiling, towering over zugibe and his bank of medical monitors. the volunteer is naked except for a pair of gym shorts and a hearty mustache. he wears the unconcerned, mildly zoned-out expression of a person waiting at a bus stop. neither man appears to have been self-conscious about being photographed this way. i think that when you get yourself down deep into a project like this, you lose sight of how odd you must appear to the rest of the world.
Mary Roach (Stiff: The Curious Lives of Human Cadavers)
In 1999 the RAND Corporation published a report (the first and, so far, last of its kind) with a “conservative estimate” that more than 307 million tissue samples from more than 178 million people were stored in the United States alone. This number, the report said, was increasing by more than 20 million samples each year. The samples come from routine medical procedures, tests, operations, clinical trials, and research donations. They sit in lab freezers, on shelves, or in industrial vats of liquid nitrogen. They’re stored at military facilities, the FBI, and the National Institutes of Health.
Rebecca Skloot (The Immortal Life of Henrietta Lacks)
First thing I did was put on the inner lining of my EVA suit. Not the bulky suit itself, just the inner clothing I wear under it, including the gloves and booties. Then I got an oxygen mask from the medical supplies and some lab goggles from Vogel’s chem kit. Almost all of my body was protected and I was breathing canned air.
Andy Weir (The Martian)
The body arrived soon enough: an unclaimed corpse from a nearby medical examiner. The guinea pigs? A cinch. Undergraduates will do anything for extra credit.
William M. Bass (Death's Acre: Inside the Legendary Forensic Lab the Body Farm Where the Dead Do Tell Tales)
The traditional gross anatomy lab represented a sort of sink-or-swim mentality about dealing with death. To cope with what was being asked of them, medical students had to find ways to desensitize themselves. They quickly learned to objectify cadavers, to think of the dead as structures and tissues, and not a former human being. Humor--at the cadaver's expense--was tolerated, condoned even.
Mary Roach (Stiff: The Curious Lives of Human Cadavers)
If possible, you also want to determine the cause of death (technically, only medical examiners can determine cause of death; we anthropologists call things like stab wounds and gunshots “manner of death”). But
William M. Bass (Death's Acre: Inside the Legendary Forensic Lab the Body Farm Where the Dead Do Tell Tales)
Every improvement is a change, but not every change is an improvement. Every rationalist doubts, but not all doubts are rational. Wearing doubts doesn’t make you a rationalist any more than wearing a white medical lab coat makes you a doctor.
Eliezer Yudkowsky (Rationality: From AI to Zombies)
One could argue that these Japanese atrocities carried out were typical of the chaos and brutality that often accompany warfare; but this cannot be said for Unit 731. Much like their counterparts in Nazi Germany did in the Auschwitz Concentration Camp, the Japanese experimented on humans like lab rats, all in the name of medical and military advancement.
Derek Pua (Unit 731: The Forgotten Asian Auschwitz)
As her body empties, I feel more and more hollow. I think I must offer her some explanation, but when I look to her face, there is clear and perfect water swirling from her open mouth, a question in a language I cannot comprehend.
Christine Montross (Body of Work: Meditations on Mortality from the Human Anatomy Lab)
For those who must deal with human corpses regularly, it is easier (and, I suppose, more accurate) to think of them as objects, not people. For most physicians, objectification is mastered their first year of medical school, in the gross anatomy lab, or “gross lab,” as it is casually and somewhat aptly known. To help depersonalize the human form that students will be expected to sink knives into and eviscerate, anatomy lab personnel often swathe the cadavers in gauze and encourage students to unwrap as they go, part by part.
Mary Roach (Stiff: The Curious Lives of Human Cadavers)
Aside from its cartridge, pipette, and temperature issues, many of the other technical snafus that plagued the miniLab could be chalked up to the fact that it remained at a very early prototype stage. Less than three years was not a lot of time to design and perfect a complex medical device. These problems ranged from the robots’ arms landing in the wrong places, causing pipettes to break, to the spectrophotometers being badly misaligned. At one point, the blood-spinning centrifuge in one of the miniLabs blew up. These were all things that could be fixed, but it would take time. The company was still several years away from having a viable product that could be used on patients.
John Carreyrou (Bad Blood: Secrets and Lies in a Silicon Valley Startup)
Of course, the cadavers, in life, donated themselves freely to this fate, and the language surrounding the bodies in front of us soon changed to reflect that fact. We were instructed to no longer call them “cadavers”; “donors” was the preferred term. And yes, the transgressive element of dissection had certainly decreased from the bad old days. (Students no longer had to bring their own bodies, for starters, as they did in the nineteenth century. And medical schools had discontinued their support of the practice of robbing graves to procure cadavers—that looting itself a vast improvement over murder, a means once common enough to warrant its own verb: burke, which the OED defines as “to kill secretly by suffocation or strangulation, or for the purpose of selling the victim’s body for dissection.”) Yet the best-informed people—doctors—almost never donated their bodies. How informed were the donors, then? As one anatomy professor put it to me, “You wouldn’t tell a patient the gory details of a surgery if that would make them not consent.” Even if donors were informed enough—and they might well have been, notwithstanding one anatomy professor’s hedging—it wasn’t so much the thought of being dissected that galled. It was the thought of your mother, your father, your grandparents being hacked to pieces by wisecracking twenty-two-year-old medical students. Every time I read the pre-lab and saw a term like “bone saw,” I wondered if this would be the session in which I finally vomited. Yet I was rarely troubled in lab, even when I found that the “bone saw” in question was nothing more than a common, rusty wood saw. The closest I ever came to vomiting was nowhere near the lab but on a visit to my grandmother’s grave in New York, on the twentieth anniversary of her death. I found myself doubled over, almost crying, and apologizing—not to my cadaver but to my cadaver’s grandchildren. In the midst of our lab, in fact, a son requested his mother’s half-dissected body back. Yes, she had consented, but he couldn’t live with that. I knew I’d do the same. (The remains were returned.) In
Paul Kalanithi (When Breath Becomes Air)
For starters, of the four so-called weapons of mass destruction, three are far less massively destructive than good old-fashioned explosives.272 Radiological or “dirty” bombs, which are conventional explosives wrapped in radioactive material (obtained, for example, from medical waste), would yield only minor and short-lived elevations of radiation, comparable to moving to a city at a higher altitude. Chemical weapons, unless they are released in an enclosed space like a subway (where they would still not do as much damage as conventional explosives), dissipate quickly, drift in the wind, and are broken down by sunlight. (Recall that poison gas was responsible for a tiny fraction of the casualties in World War I.) Biological weapons capable of causing epidemics would be prohibitively expensive to develop and deploy, as well as dangerous to the typically bungling amateur labs that would develop them.
Steven Pinker (The Better Angels of Our Nature: The Decline of Violence In History And Its Causes)
Dr. Kary Mullis, who won the Nobel Prize in Chemistry for inventing PCR, stated publicly numerous times that his invention should never be used for the diagnosis of infectious diseases. In July of 1997, during an event called Corporate Greed and AIDS in Santa Monica CA, Dr. Mullis explained on video, “With PCR you can find almost anything in anybody. It starts making you believe in the sort of Buddhist notion that everything is contained in everything else, right? I mean, because if you can model amplify one single molecule up to something that you can really measure, which PCR can do, then there’s just very few molecules that you don’t have at least one single one of them in your body. Okay? So that could be thought of as a misuse of it, just to claim that it’s meaningful.” Mikki explained, “The major issue with PCR is that it’s easily manipulated. It functions through a cyclical process whereby each revolution amplifies magnification. On a molecular level, most of us already have trace amounts of genetic fragments similar to coronavirus within us. By simply over-cycling the process, a negative result can be flipped to a positive. Governing bodies such as the CDC and the WHO can control the number of cases by simply advising the medical industry to increase or decrease the cycle threshold (CT).” In August of 2020, the New York Times reported that “a CT beyond 34 revolutions very rarely detect live virus, but most often, dead nucleotides that are not even contagious. In compliance with guidance from the CDC and the WHO, many top US labs have been conducting tests at cycle thresholds of 40 or more. NYT examined data from Massachusetts, New York, and Nevada and determined that up to 90 percent of the individuals who tested positive carried barely any virus.”17 90 percent! In May of 2021, CDC changed the PCR cycle threshold from 40 to 28 or lower for those who have been vaccinated. This one adjustment of the numbers allowed the vaccine pushers to praise the vaccines as a big success.
Mikki Willis (Plandemic: Fear Is the Virus. Truth Is the Cure.)
But the problem arises when instead of setting aside our natural reactions, they are denied altogether. Then the culture simply becomes superhuman. And thus is the realm of the superhuman there is no room for human frailty, and admission of it by one risks revealing the illusion of the many. So no one speaks up, and as a result each person believes that she is alone in her experience. To that end, we are left in a profession of untouchable greatness and infallibility, but one whose members kill themselves more than others.
Christine Montross (Body of Work: Meditations on Mortality from the Human Anatomy Lab)
Because the second wave was so much more severe than the first, a lot of people refused to believe it could be the same disease. It had to be terrorism. They didn't care what medical experts kept telling them, about how it was the nature of influenza to occur in waves and that there was nothing about this pandemic, terrible though it was, that wasn't happening more or less as had long been predicted. No, not bioterrorism, others said, but a virus that had escaped from a laboratory. These were the same people who believed that both Lyme disease and West Nile virus were caused by germs that had escaped many years ago from a government lab off the coast of Long Island. They scoffed at the assertion that it was impossible to say for sure where the flu had begun because cases had appeared in several different countries at exactly the same time. Cover-up! Everyone knew the government was involved in the development of bioweapons. And although the Americans were not the only ones who were working on such weapons, the belief that they were somehow to blame--that the monster germ had most likely been created in an American lab, for American military purposes--would outlive the pandemic itself. In any case, according to a poll, eighty-two percent of Americans believed the government knew more about the flu than it was saying. And the number of people who declared themselves dead set against any vaccine the government came up with was steadily growing.
Sigrid Nunez (Salvation City)
By now, certain alternate theories are beginning to circulate online. It's the government, they say. Or it's Big Pharma. Some kind of germ must have gotten loose from a lab at the college. Think about it, they say: Do you really believe that a completely new virus could show up in the most powerful country on earth without scientists knowing exactly what it is? They probably engineered it themselves. They might be spreading this thing on purpose, testing out a biological weapon. They might be withholding the cure. Or maybe there's no sickness at all—that's what some have begun posting online. Isn't Santa Lora the perfect location for a hoax? An isolated town, surrounded by forest, only one road in and one road out. And those people you see on TV? Those could be hired victims. Those could be crisis actors paid to play their parts. And the supposedly sick? Come on, how hard is it to pretend you're asleep? Maybe, a few begin to say, Santa Lora is not even a real town. Has anyone ever heard of this place? And look it up: there's no such saint as Santa Lora. It's made-up. The whole damn place is probably just a set on some back lot in Culver City. Don't those houses look a little too quaint? Don't be naïve, say others—they don't need a set. All that footage is probably just streaming out of some editing room in the valley. If you look closely, you can tell that some of those houses repeat. Now just ask yourself, they say, who stands to benefit from all this. It always comes back to money, right? The medical-industrial complex. And who do you think pays the salaries of these so-called journalists reporting all this fake news? Just watch: in a few months, Big Pharma will be selling the vaccine.
Karen Thompson Walker (The Dreamers)
In 1950, a thirty-year-old scientist named Rosalind Franklin arrived at King’s College London to study the shape of DNA. She and a graduate student named Raymond Gosling created crystals of DNA, which they bombarded with X-rays. The beams bounced off the crystals and struck photographic film, creating telltale lines, spots, and curves. Other scientists had tried to take pictures of DNA, but no one had created pictures as good as Franklin had. Looking at the pictures, she suspected that DNA was a spiral-shaped molecule—a helix. But Franklin was relentlessly methodical, refusing to indulge in flights of fancy before the hard work of collecting data was done. She kept taking pictures. Two other scientists, Francis Crick and James Watson, did not want to wait. Up in Cambridge, they were toying with metal rods and clamps, searching for plausible arrangements of DNA. Based on hasty notes Watson had written during a talk by Franklin, he and Crick put together a new model. Franklin and her colleagues from King’s paid a visit to Cambridge to inspect it, and she bluntly told Crick and Watson they had gotten the chemistry all wrong. Franklin went on working on her X-ray photographs and growing increasingly unhappy with King’s. The assistant lab chief, Maurice Wilkins, was under the impression that Franklin was hired to work directly for him. She would have none of it, bruising Wilkins’s ego and leaving him to grumble to Crick about “our dark lady.” Eventually a truce was struck, with Wilkins and Franklin working separately on DNA. But Wilkins was still Franklin’s boss, which meant that he got copies of her photographs. In January 1953, he showed one particularly telling image to Watson. Now Watson could immediately see in those images how DNA was shaped. He and Crick also got hold of a summary of Franklin’s unpublished research she wrote up for the Medical Research Council, which guided them further to their solution. Neither bothered to consult Franklin about using her hard-earned pictures. The Cambridge and King’s teams then negotiated a plan to publish a set of papers in Nature on April 25, 1953. Crick and Watson unveiled their model in a paper that grabbed most of the attention. Franklin and Gosling published their X-ray data in another paper, which seemed to readers to be a “me-too” effort. Franklin died of cancer five years later, while Crick, Watson, and Wilkins went on to share the Nobel prize in 1962. In his 1968 book, The Double Helix, Watson would cruelly caricature Franklin as a belligerent, badly dressed woman who couldn’t appreciate what was in her pictures. That bitter fallout is a shame, because these scientists had together discovered something of exceptional beauty. They had found a molecular structure that could make heredity possible.
Carl Zimmer (She Has Her Mother's Laugh: What Heredity Is, Is Not, and May Become)
Astonishment: these women’s military professions—medical assistant, sniper, machine gunner, commander of an antiaircraft gun, sapper—and now they are accountants, lab technicians, museum guides, teachers…Discrepancy of the roles—here and there. Their memories are as if not about themselves, but some other girls. Now they are surprised at themselves. Before my eyes history “humanizes” itself, becomes like ordinary life. Acquires a different lighting. I’ve happened upon extraordinary storytellers. There are pages in their lives that can rival the best pages of the classics. The person sees herself so clearly from above—from heaven, and from below—from the ground. Before her is the whole path—up and down—from angel to beast. Remembering is not a passionate or dispassionate retelling of a reality that is no more, but a new birth of the past, when time goes in reverse. Above all it is creativity. As they narrate, people create, they “write” their life. Sometimes they also “write up” or “rewrite.” Here you have to be vigilant. On your guard. At the same time pain melts and destroys any falsehood. The temperature is too high! Simple people—nurses, cooks, laundresses—behave more sincerely, I became convinced of that…They, how shall I put it exactly, draw the words out of themselves and not from newspapers and books they have read—not from others. But only from their own sufferings and experiences. The feelings and language of educated people, strange as it may be, are often more subject to the working of time. Its general encrypting. They are infected by secondary knowledge. By myths. Often I have to go for a long time, by various roundabout ways, in order to hear a story of a “woman’s,” not a “man’s” war: not about how we retreated, how we advanced, at which sector of the front…It takes not one meeting, but many sessions. Like a persistent portrait painter. I sit for a long time, sometimes a whole day, in an unknown house or apartment. We drink tea, try on the recently bought blouses, discuss hairstyles and recipes. Look at photos of the grandchildren together. And then…After a certain time, you never know when or why, suddenly comes this long-awaited moment, when the person departs from the canon—plaster and reinforced concrete, like our monuments—and goes on to herself. Into herself. Begins to remember not the war but her youth. A piece of her life…I must seize that moment. Not miss it! But often, after a long day, filled with words, facts, tears, only one phrase remains in my memory (but what a phrase!): “I was so young when I left for the front, I even grew during the war.” I keep it in my notebook, although I have dozens of yards of tape in my tape recorder. Four or five cassettes… What helps me? That we are used to living together. Communally. We are communal people. With us everything is in common—both happiness and tears. We know how to suffer and how to tell about our suffering. Suffering justifies our hard and ungainly life.
Svetlana Alexievich (War's Unwomanly Face)
I lost my first patient on a Tuesday. She was an eighty-two-year-old woman, small and trim, the healthiest person on the general surgery service, where I spent a month as an intern. (At her autopsy, the pathologist would be shocked to learn her age: “She has the organs of a fifty-year-old!”) She had been admitted for constipation from a mild bowel obstruction. After six days of hoping her bowels would untangle themselves, we did a minor operation to help sort things out. Around eight P.M. Monday night, I stopped by to check on her, and she was alert, doing fine. As we talked, I pulled from my pocket my list of the day’s work and crossed off the last item (post-op check, Mrs. Harvey). It was time to go home and get some rest. Sometime after midnight, the phone rang. The patient was crashing. With the complacency of bureaucratic work suddenly torn away, I sat up in bed and spat out orders: “One liter bolus of LR, EKG, chest X-ray, stat—I’m on my way in.” I called my chief, and she told me to add labs and to call her back when I had a better sense of things. I sped to the hospital and found Mrs. Harvey struggling for air, her heart racing, her blood pressure collapsing. She wasn’t getting better no matter what I did; and as I was the only general surgery intern on call, my pager was buzzing relentlessly, with calls I could dispense with (patients needing sleep medication) and ones I couldn’t (a rupturing aortic aneurysm in the ER). I was drowning, out of my depth, pulled in a thousand directions, and Mrs. Harvey was still not improving. I arranged a transfer to the ICU, where we blasted her with drugs and fluids to keep her from dying, and I spent the next few hours running between my patient threatening to die in the ER and my patient actively dying in the ICU. By 5:45 A.M., the patient in the ER was on his way to the OR, and Mrs. Harvey was relatively stable. She’d needed twelve liters of fluid, two units of blood, a ventilator, and three different pressors to stay alive. When I finally left the hospital, at five P.M. on Tuesday evening, Mrs. Harvey wasn’t getting better—or worse. At seven P.M., the phone rang: Mrs. Harvey had coded, and the ICU team was attempting CPR. I raced back to the hospital, and once again, she pulled through. Barely. This time, instead of going home, I grabbed dinner near the hospital, just in case. At eight P.M., my phone rang: Mrs. Harvey had died. I went home to sleep.
Paul Kalanithi (When Breath Becomes Air)
George Gey paid his way through a biology degree at the University of Pittsburgh by working as a carpenter and mason, and he could make nearly anything for cheap or free. During his second year in medical school, he rigged a microscope with a time-lapse motion picture camera to capture live cells on film. It was a Frankensteinish mishmash of microscope parts, glass, and 16-millimeter camera equipment from who knows where, plus metal scraps, and an old motor from Shapiro’s junkyard. He built it in a hole he’d blasted in the foundation of Hopkins, right below the morgue, its base entirely underground and surrounded by a thick wall of cork to keep it from jiggling when streetcars passed. At night, a Lithuanian lab assistant slept next to the camera on a cot, listening to its constant tick, making sure it stayed stable through the night, waking every hour to refocus it. With that camera, Gey and his mentor, Warren Lewis, filmed the growth of cells, a process so slow - like the growth of a flower - the naked eye couldn’t see it. They played the film at high speed so they could watch cell division on the screen in one smooth motion, like a story unfolding in a flip book.
skloot, Rebecca
respectively. Diane Claridge Dolphin and beaked whale researcher; wife and research partner of Ken Balcomb. Darlene Ketten Whale and human hearing expert; forensic pathologist, Harvard Medical School and Woods Hole Oceanographic Institution. Roger Payne First cetologist to decode and promote humpback whale song and conservation. Chris Clark Director, Bioacoustics Research Program, Cornell University Lab of Ornithology; protégé of Roger Payne.
Joshua Horwitz (War of the Whales: A True Story)
The GTT he administered showed severe reactive hypoglycemia (RHG). At that time, one of the many criticisms of Dr. Atkins was that he diagnosed many with RHG. For this he was called a “quack”. After seeing the lab results, I immediately began the Induction phase of his diet and soon felt better, just as his patients did. As long as I ate correctly and didn’t skip meals I rarely experienced my prior symptoms. That remains true to this day. This was my first lesson in the power of practical nutrition (albeit outside of mainstream medical opinion). I am convinced that if I hadn’t followed Dr. Atkins advice I would have had type 2 diabetes long ago. I can thank him for many things but most especially for that.
Jeff S. Volek (The Art and Science of Low Carbohydrate Living: An Expert Guide to Making the Life-Saving Benefits of Carbohydrate Restriction Sustainable and Enjoyable)
one of FerroKin’s most important solutions to the cost problem is to have no physical office, instead relying on wireless phones and home internet connections to coordinate an intensive round of pre-clinical investigations and regulatory filings. “We wanted to do this from our homes,” he says, because putting a premium on being in the same physical location every day and attending endless meetings unnecessarily constrains whom you can hire and what work skills you pay for in an employee. Sensitive medical information can be secured digitally even as it is shared among distributed team members and the outsourced labs and clinics that are performing the work. As a result, digital reduces the barriers to focusing on the job at hand.
James McQuivey (Digital Disruption: Unleashing the Next Wave of Innovation)
My father's concern for his patients was only enhanced by the fact that so many of them had a personal connection to him...In the words of the historian David J. Rothman, 'doctor and patient occupied the same social space,' promoting a shared relationship. Meanwhile, the poor and minority patients my dad met for the first time at the Mount Sinai--including many he would then follow for years--got the same royal treatment...His goal was to 'take extra pains with the service patients, to be certain they are reassured and confident in your care, and come to believe that you really care about him or her as an individual.' One way he did this was to take advantage of his flexible schedule. 'It's so simple,' he wrote, 'to make an extra visit in the afternoon for these special cases, come back to report a new lab test result, review an X-ray [or] reassure that the scheduled test is necessary, important and will lead to some conclusive information.' Illness, he underscored, was 'frightening.
Barron H. Lerner (The Good Doctor: A Father, a Son, and the Evolution of Medical Ethics)
The dissection of Hawkeye will begin in ten minutes. All necessary personnel please report to the medical lab.
Chelsea Cain (Mockingbird #4)
In the lab, Snow World consistently cuts pain scores by 35%, says Hoffman, compared to around 5% for music. And when used in combination with pain medication, it reduces patients’ pain ratings by an extra 15–40% on top of what they get with drugs.9 The researchers see the effects not just in subjective pain scores but in brain scans too, with activity in pain-related brain areas almost completely extinguished.
Jo Marchant (Cure: A Journey into the Science of Mind Over Body)
We raided the lab. Unsure of exactly what the medical needs of a profane aberration might be,
Jeremy Robert Johnson (Skullcrack City)
Marc Goodman is a cyber crime specialist with an impressive résumé. He has worked with the Los Angeles Police Department, Interpol, NATO, and the State Department. He is the chief cyber criminologist at the Cybercrime Research Institute, founder of the Future Crime Institute, and now head of the policy, law, and ethics track at SU. When breaking down this threat, Goodman sees four main categories of concern. The first issue is personal. “In many nations,” he says, “humanity is fully dependent on the Internet. Attacks against banks could destroy all records. Someone’s life savings could vanish in an instant. Hacking into hospitals could cost hundreds of lives if blood types were changed. And there are already 60,000 implantable medical devices connected to the Internet. As the integration of biology and information technology proceeds, pacemakers, cochlear implants, diabetic pumps, and so on, will all become the target of cyber attacks.” Equally alarming are threats against physical infrastructures that are now hooked up to the net and vulnerable to hackers (as was recently demonstrated with Iran’s Stuxnet incident), among them bridges, tunnels, air traffic control, and energy pipelines. We are heavily dependent on these systems, but Goodman feels that the technology being employed to manage them is no longer up to date, and the entire network is riddled with security threats. Robots are the next issue. In the not-too-distant future, these machines will be both commonplace and connected to the Internet. They will have superior strength and speed and may even be armed (as is the case with today’s military robots). But their Internet connection makes them vulnerable to attack, and very few security procedures have been implemented to prevent such incidents. Goodman’s last area of concern is that technology is constantly coming between us and reality. “We believe what the computer tells us,” says Goodman. “We read our email through computer screens; we speak to friends and family on Facebook; doctors administer medicines based upon what a computer tells them the medical lab results are; traffic tickets are issued based upon what cameras tell us a license plate says; we pay for items at stores based upon a total provided by a computer; we elect governments as a result of electronic voting systems. But the problem with all this intermediated life is that it can be spoofed. It’s really easy to falsify what is seen on our computer screens. The more we disconnect from the physical and drive toward the digital, the more we lose the ability to tell the real from the fake. Ultimately, bad actors (whether criminals, terrorists, or rogue governments) will have the ability to exploit this trust.
Peter H. Diamandis (Abundance: The Future is Better Than You Think)
The hallmark of originality is rejecting the default and exploring whether a better option exists. I’ve spent more than a decade studying this, and it turns out to be far less difficult than I expected. The starting point is curiosity: pondering why the default exists in the first place. We’re driven to question defaults when we experience vuja de, the opposite of déjà vu. Déjà vu occurs when we encounter something new, but it feels as if we’ve seen it before. Vuja de is the reverse—we face something familiar, but we see it with a fresh perspective that enables us to gain new insights into old problems. Without a vuja de event, Warby Parker wouldn’t have existed. When the founders were sitting in the computer lab on the night they conjured up the company, they had spent a combined sixty years wearing glasses. The product had always been unreasonably expensive. But until that moment, they had taken the status quo for granted, never questioning the default price. “The thought had never crossed my mind,” cofounder Dave Gilboa says. “I had always considered them a medical purchase. I naturally assumed that if a doctor was selling it to me, there was some justification for the price.” Having recently waited in line at the Apple Store to buy an iPhone, he found himself comparing the two products. Glasses had been a staple of human life for nearly a thousand years, and they’d hardly changed since his grandfather wore them. For the first time, Dave wondered why glasses had such a hefty price tag. Why did such a fundamentally simple product cost more than a complex smartphone? Anyone could have asked those questions and arrived at the same answer that the Warby Parker squad did. Once they became curious about why the price was so steep, they began doing some research on the eyewear industry. That’s when they learned that it was dominated by Luxottica, a European company that had raked in over $7 billion the previous year. “Understanding that the same company owned LensCrafters and Pearle Vision, Ray-Ban and Oakley, and the licenses for Chanel and Prada prescription frames and sunglasses—all of a sudden, it made sense to me why glasses were so expensive,” Dave says. “Nothing in the cost of goods justified the price.” Taking advantage of its monopoly status, Luxottica was charging twenty times the cost. The default wasn’t inherently legitimate; it was a choice made by a group of people at a given company. And this meant that another group of people could make an alternative choice. “We could do things differently,” Dave suddenly understood. “It was a realization that we could control our own destiny, that we could control our own prices.” When we become curious about the dissatisfying defaults in our world, we begin to recognize that most of them have social origins: Rules and systems were created by people. And that awareness gives us the courage to contemplate how we can change them. Before women gained the right to vote in America, many “had never before considered their degraded status as anything but natural,” historian Jean Baker observes. As the suffrage movement gained momentum, “a growing number of women were beginning to see that custom, religious precept, and law were in fact man-made and therefore reversible.
Adam M. Grant (Originals: How Non-Conformists Move the World)
Most recently, as the medical value of marijuana has been rediscovered, medicine has been searching for ways to “pharmaceuticalize” the plant—find a way to harness its easily accessible benefits in a patch or inhaler that doctors can prescribe, corporations patent, and governments regulate. Whenever possible, Paracelsus’s lab-coated descendants have synthesized the active ingredients in plant drugs, allowing medicine to dispense with the plant itself—and any reminders of its pagan past.
Michael Pollan (The Botany of Desire: A Plant's-Eye View of the World)
The audio system piped Civil War-era piano into the examining room, lending the lab a strangely dichotomous feel of the modern twenty-first century medical facility and the late nineteenth century, when you poured whiskey over a bullet wound and hoped for the best. He could picture himself in a saloon after the end of the Civil War at the same time as he stood in the white and stainless steel lab.
Nina Post (Danger Returns in Pairs (Shawn Danger Mysteries Book 2))
The medical lab, whether it’s in a hospital or stand-alone, will eventually become a thing of the past.
Robin Farmanfarmaian (The Patient as CEO: How Technology Empowers the Healthcare Consumer)
You sign up and give Picnic permission to get your medical records from all your doctors and providers, including scans and lab results. They combine it into one easy-to-read patient dashboard that’s accessible just to you as the patient.
Robin Farmanfarmaian (The Patient as CEO: How Technology Empowers the Healthcare Consumer)
And so, just as the humanity of our cadavers asserts itself in nail polish and tattoos, the inverse of humanity emerges in the body's utter lack of response to profound wounds.
Christine Montross (Body of Work: Meditations on Mortality from the Human Anatomy Lab)
Perhaps less pernicious but still worrisome is reliance on “wellness” programs, which most medium to large employers in the United States have, despite the fact that, overall, they have not been validated to promote health outcomes. Typically, a wellness program combines step counting, weight and blood pressure readings, and cholesterol lab tests, as well as some incentive for employees to participate (such as a surcharge on an employee’s contribution to the cost of insurance). But wellness is poorly defined, and the cost effectiveness of such strategies has been seriously questioned.50 One way such programs could be improved, however, is through the use of virtual medical coaches, which could gather and make use of far more granular and deeper information about each individual.
Eric J. Topol (Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again)
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Clifford” is an important psychedelic researcher, group leader, and writer. He is currently writing a book of personal essays. Student days at the University of California at San Diego were a whirlwind blending of 1960s’ issues with the academic pressure necessary to enter postgraduate training of some sort. My personal choices were between psychology and medicine. My introduction to psychedelics had convinced me of their value. I was taking a biology course to prepare for medical school, and we were studying the development of the chick embryo. After the first meeting of the one-quarter-long course, I realized that in order to stay alert, a tiny dose of LSD could be useful. With that in mind, I licked a small, but very potent, tablet emblazoned with the peace sign before every class. This produced a barely noticeable brightening of colors and created a generalized fascination with the course and my professor, who was otherwise uninteresting to me. Unfortunately, when finals came around, my health disintegrated and I missed the final exam. The next day I called my professor and begged for mercy. She said, “No problem, come to my lab.” “When shall we schedule this?” She suggested immediately. With some dismay, I agreed that I would meet her within an hour. I reached into the freezer and licked the almost exhausted fragment of the tablet I had used for class. I decided that there was so little left I might as well swallow it all. At
James Fadiman (The Psychedelic Explorer's Guide: Safe, Therapeutic, and Sacred Journeys)
In the current ethos of privatization, the incarcerated are often soaked even further with fees for their own imprisonment, sometimes including their housing, also food, supplies, and even medical lab fees. Corporations
Mark Lewis Taylor (The Executed God: The Way of the Cross in Lockdown America)
A furious researcher stumbled out of one of the lab buildings and shouted, 'I'm a scientist working on the AIDS cure. Why are you here? You are making too much noise.' It was a statement that epitomized the vast and growing rift between scientists and patients.
Siddhartha Mukherjee (The Emperor of All Maladies: A Biography of Cancer)
The most alarming moments of anatomy are not the bizarre, the unknown. They are the familiar.
Christine Montross (Body of Work: Meditations on Mortality from the Human Anatomy Lab)
I feel your body, your sick and scared body. And I feel how it must be different from how it was, and how it is different from mine.
Christine Montross (Body of Work: Meditations on Mortality from the Human Anatomy Lab)
Readers of these pages will learn how in exalting patented medicine Dr. Fauci has, throughout his long career, routinely falsified science, deceived the public and physicians, and lied about safety and efficacy. Dr. Fauci’s malefactions detailed in this volume include his crimes against the hundreds of Black and Hispanic orphan and foster children whom he subjected to cruel and deadly medical experiments and his role, with Bill Gates, in transforming hundreds of thousands of Africans into lab rats for low-cost clinical trials of dangerous experimental drugs that, once approved, remain financially out of reach for most Africans. You will learn how Dr. Fauci and Mr. Gates have turned the African continent into a dumping ground for expired, dangerous, and ineffective drugs, many of them discontinued for safety reasons in the US and Europe.
Robert F. Kennedy Jr. (The Real Anthony Fauci: Bill Gates, Big Pharma, and the Global War on Democracy and Public Health)
Why are you asking me?" Viv said. "Ask your lovely girlfriend." Tim's lips cinched into a happy little knot. Viv looked at him looking at Davida and thought how it was like watching some lab experiment. Bubbles of mercury running into each other's arms. Iron filings performing their mating dance for the magnet. Cesium exploding at the lightest touch of H2O. Exactly what the laws of chemistry demanded. It was as science-y as that. He'd found his person.
Vicki Grant (Tell Me When You Feel Something)
his five-decade dictatorial control of the FBI to transform the agency into a vehicle for shielding organized crime, fortifying his corrupt political partners, oppressing Black Americans, surveilling his political enemies, suppressing free speech and dissent, and as a platform for building a cult of personality around his own inflated ego. More recently, Dr. Fauci’s perennial biographer, Charles Ortleb, analogized Dr. Fauci’s career and pathological mendacity to the sociopathic con men Bernie Madoff and Charles Ponzi.37 Another critic, author J. B. Handley, labeled Dr. Fauci “a snake oil salesman” and a “bigger medical charlatan than Rasputin.”38 Economist and author Peter Navarro, former Director of Trade and Manufacturing Policy, observed during a national network television interview in April 2021 that “Fauci is a sociopath and a liar.”39 His white lab coat, his official title, and his groaning bookshelves crowded with awards from his medical cartel collaborators allow Dr. Fauci to masquerade as a neutral, disinterested scientist and selfless public servant driven by a relentless commitment to public health. But Dr. Fauci doesn’t really do public health. By every metric, his fifty-year regime has been a catastrophe for American health. But as a businessman, his success has been boundless. In 2010, Dr. Fauci told adoring New Yorker writer Michael Specter that his go-to political playbook is Mario Puzo’s novel The Godfather.40 He spontaneously recited his favorite line from Puzo’s epic: “It’s nothing personal, it’s strictly business.
Robert F. Kennedy Jr. (The Real Anthony Fauci: Bill Gates, Big Pharma, and the Global War on Democracy and Public Health)
Our lives are, in so many ways, shaped by the microorganisms that live on us, inside us, and around us. The estimated forty trillion bacteria in our gut, for example, help us digest everything we eat. Disturbing the healthy bacteria that colonize our gut can lead to dangerous blood infections. Today, to diagnose blood infections like those or lung infections like pneumonia, we take a sample of blood or sputum and grow the accompanying bacteria in a lab under special conditions. Eventually, the bacteria are stained and inspected under the microscope and exposed to various antibiotics to determine which ones can kill them. This process takes days. Meanwhile, we treat the patient with our “best guess” antibiotics. In the future, we will sequence those bacteria immediately and map their DNA to
Euan Angus Ashley (The Genome Odyssey: Medical Mysteries and the Incredible Quest to Solve Them)
The first vaccine for smallpox was developed at the end of the 18th century, and by the end of the 19th century, the disease had become comparatively rare in most industrialized countries. In the 20th century, medical advances made the vaccine easier to produce and transport around the world, leading to a global campaign to eradicate smallpox completely. It succeeded: the last smallpox infection “in the wild” occurred in Somalia in 1977, and the last outbreak in history—and the final smallpox death—happened after a lab accident in 1978.
Randall Munroe (How To: Absurd Scientific Advice for Common Real-World Problems)
The next day, Trump toured Fauci’s lab, the NIH Vaccine Research Center, as part of the White House effort to showcase the president’s determination to speed up the creation of a vaccine. Fauci again reminded Trump that getting a vaccine in a year was wildly optimistic. At the end of the tour, Fauci and Azar drove with the president across Wisconsin Avenue from the NIH campus to the helipad at Walter Reed National Military Medical Center, where Marine One awaited to fly Trump back to the White House. “So how’s Francis Collins doing?” the president asked Azar, referring to the NIH director they had just said goodbye to. “He’s really helped us on the fetal tissue ban,” Azar said. He referred to Trump’s 2019 decision to dramatically cut government funding at NIH and elsewhere for medical research that relied on tissues of aborted fetuses. This was a move to please antiabortion conservatives, a key part of the president’s political base. Collins didn’t agree with the policy, Azar told Trump, but was “being very professional in implementing it.” Azar was surprised when Trump asked, “Is that fetal tissue issue going to slow down the vaccine and therapies?” When he learned the answer was yes, the president said he wanted them to reverse the ban, but that never happened.
Carol Leonnig (I Alone Can Fix It: Donald J. Trump's Catastrophic Final Year)
The most common food allergens are products made from cow milk, gluten grains (wheat, oats, rye, barley, spelt, and kamut), and soy. Food allergies can be formally identified through blood tests done by a medical lab.
Rick Hanson (Buddha's Brain: The Practical Neuroscience of Happiness, Love, and Wisdom)
exit. But that gave Carlson time to regain his bluster. “Again, what do you want? You can’t just come busting into my office.” “This is me being nice and giving you a chance to talk here,” Karen said. “Do you want me to drag you down to the police station in handcuffs instead?” Carlson’s mouth moved, but nothing came out. Maybe he was starting to realize that playing the bully wasn’t going to do the trick. “Do you know Sergei Turgenev?” I asked. “Of course, he’s one of my visiting scientists. A good man, chemistry PhD from Moscow State University.” “How is he in the lab?” I asked. “Seem to know his stuff?” Carlson fidgeted in his chair. “Well, he’s only been here a few months.
Geoffrey M. Cooper (Bad Medicine: A Medical Thriller (Brad Parker and Karen Richmond, #3)
Blood glucose instability is a huge problem that affects the moods of millions of people. The brain accounts for only about 2 percent of body weight, but requires 25 percent of all blood pumped by the heart (up to 50 percent in kids). Therefore, low blood sugar hits the brain hard, causing depression, anxiety, and lassitude. If you often become uncomfortably hungry, you’ve got a serious problem and should solve it. Eat high-protein, nutrient-dense meals, and snack enough to keep your blood sugar up, but not with insulin-stimulating sweets or starches. Remember that hunger kills brain cells, just like getting drunk. Be careful of caffeine, which causes blood sugar swings, and never crash diet. Food sensitivities are common reactions that are not classic food allergies, so most conventional allergists underestimate the damage they do. They play a major role in mood disruption, much more frequently than most people realize. They cause chemical reactions in the body that destabilize blood sugar and wreak havoc upon hormonal and neurotransmitter balance. This can trigger depression, anxiety, impaired concentration, insomnia, and hyperactivity. The most common sensitivities, unfortunately, are to the foods people most often overconsume: wheat, milk, eggs, corn, soy, and peanuts. The average American gets about 75 percent of her calories from just 10 favorite foodstuffs, and this narrow range of eating disrupts the digestive process and causes abnormal reactions. If a particular food doesn’t agree with you and commonly causes heartburn, gas, bloating, water weight gain, a craving for more, or a burst of nervous energy, you’re probably reactive to it. There are several good books on the subject, and there are many labs that test for sensitivities. Ask a chiropractor, naturopath, or doctor of integrative medicine about them. Don’t expect much help from a conventional allergist. Exercise and Mood Dozens of studies indicate that exercise is often as effective for depression as medication, partly because it increases production of stimulating hormones, such as norepinephrine, and also because it increases oxygen flow to the brain. Exercise can, in addition, help relieve and prevent anxiety, creating a so-called tranquilizer effect that persists for about 4 hours after exercising. Exercise also decreases the biological stress response, which dampens the automatic fear reaction. It is also uniquely effective at causing secretion of Nerve Growth Factor, one of the limited number of substances that cause brain cells to grow. Another benefit of exercise is that it increases endorphin output by about 500 percent and decreases the incidence of major and minor illnesses. For mood, the ideal amount is 30 to 45 minutes of cardiovascular exercise daily. Studies show that exercising less than 30 minutes or more than 1 hour decreases mood benefits.
Dan Baker (What Happy People Know: How the New Science of Happiness Can Change Your Life for the Better)
On December 22, 1895, Röntgen brought his wife into the lab. This time, instead of using a sheet of paper coated with a fluorescent chemical, he used a glass photographic plate to capture the image permanently. He asked his wife to put her hand between the tube and the glass plate and to keep it there for fifteen minutes. When she saw the bones of her hand, as well as an outline of the signet ring on her finger, she screamed, “I have seen my own death!” This was the response to the world’s first permanent radiograph.
Paul A. Offit (You Bet Your Life: From Blood Transfusions to Mass Vaccination, the Long and Risky History of Medical Innovation)
Several weeks of the elimination/provocation diet in conjunction with a high-quality detoxification powder clears up common digestive complaints such as gas, bloating, diarrhea, and constipation for many people. If a digestive problem still persists, I run a GI stool and salivary panel to see if parasites or other pathogens are causing problems. It’s not uncommon to find infections by an amoeba, Giardia, roundworms, candida yeast, excess bacteria, or other pathogens affecting the person’s gut health. How to eradicate these parasites and pathogens is beyond the scope of this book, and methods vary. There are situations in which I will recommend drugs instead of herbal remedies, because medications are ultimately more effective and easier on my patient. Herbal remedies, on the other hand, work well for many other conditions, including candida overgrowth271 and h.pylori bacteria.272
Datis Kharrazian (Why Do I Still Have Thyroid Symptoms? When My Lab Tests Are Normal: A revolutionary breakthrough in understanding Hashimoto’s disease and hypothyroidism)
Roy Porter’s The Greatest Benefit to Mankind: A Medical History of Humanity, Henry Harris’s The Birth of the Cell, and Laura Otis’s Müller’s Lab
Siddhartha Mukherjee (The Song of the Cell: An Exploration of Medicine and the New Human)
Kozhevnikov, a lecturer at Harvard Medical School and a researcher at the visual-spatial cognition lab at Massachusetts General Hospital, is one of the first scientists to differentiate between two kinds of visual thinkers: spatial visualizers and object visualizers. In her 2002 landmark
Temple Grandin (Visual Thinking: The Hidden Gifts of People Who Think in Pictures, Patterns, and Abstractions)
While a 'cure' for HIV would, in effect, decrease Gilead's market share, PrEP not only allows for the capture of those who are HIV+ but has transformed all those who are not into consumers - market saturation as a way of life. Because of PrEP's prohibitive cost, many of those most impacted by HIV, namely young Black, Indigenous, and/or Latinx trans women and MSM as well as IV drug users, have limited, if any, access. The ongoing legacies of colonial medical disinformation swirls with transphobic epidemiology and the homicidal stigmatization of IV drug use that results in the uninterruption of the pandemic for some, while the end of AIDS is habitually proclaimed for others. In a lethal irony, it is the logic of the patent - the argument that innovation is only spurred by the security of private property - that replicates the virus and its differential death. Put plainly, the HIV cells of those taken without their informed consent or compensation, housed in the NIH reagent bank and also laboring in publicly funded labs that produced PrEP, are withheld from the same populations, and perhaps the same people from whom they were initially extracted. The theft of their viral labor helped grow Gilead's incalculable wealth, which includes $36.2 billion in earnings off Truvada alone.
Eric A. Stanley (Atmospheres of Violence: Structuring Antagonism and the Trans/Queer Ungovernable)
Nutritional supplements may give you false or inaccurate results on medical laboratory tests.
Steven Magee (Pandemic Supplements)
His white lab coat, his official title, and his groaning bookshelves crowded with awards from his medical cartel collaborators allow Dr. Fauci to masquerade as a neutral, disinterested scientist and selfless public servant driven by a relentless commitment to public health. But Dr. Fauci doesn’t really do public health. By every metric, his fifty-year regime has been a catastrophe for American health. But as a businessman, his success has been boundless.
Robert F. Kennedy Jr. (The Real Anthony Fauci: Bill Gates, Big Pharma, and the Global War on Democracy and Public Health)
once compared Noetic Scientists to the early explorers who were mocked for embracing the heretical notion of a spherical earth. Almost overnight, these explorers went from fools to heroes, discovering uncharted worlds and expanding the horizons of everyone on the planet. Peter thinks you will do this as well. He has very high hopes for your work. After all, every great philosophical shift in history began with a single bold idea.” Galloway knew, of course, that one needn’t go to a lab to witness proof of this bold new idea, this proposal of man’s untapped potential. This very cathedral held healing prayer circles for the sick, and repeatedly had witnessed truly miraculous results, medically documented physical transformations. The question was not whether God had imbued man with great powers . . . but rather how we liberate those powers.
Dan Brown (The Lost Symbol (Robert Langdon, #3))
I spend most of my Mondays with blood. I am a hematologist by training. I study blood and treat blood diseases, including cancers and precancers of white blood cells. On Monday, I arrive much earlier than my patients, when the morning light is still aslant across the black slate of the lab benches. I close the shutters and peer through the microscope at blood smears. A droplet of blood has been spread across a glass slide, to make a film of single cells, each stained with special dyes. The slides are like previews of books, or movie trailers. The cells will begin to reveal the stories of the patients even before I see them in person. I sit by the microscope in the darkened room, a notepad by my side, and whisper to myself as I go through the slides. It’s an old habit; a passerby might well consider me unhinged. Each time I examine a slide, I mumble out the method that my hematology professor in medical school, a tall man with a perpetually leaking pen in his pocket, taught me: “Divide the main cellular components of blood. Red cell. White cell. Platelet. Examine each cell type separately. Write what you observe about each type. Move methodically. Number, color, morphology, shape, size.” It is, by far, the favorite time of my day at work. Number, color, morphology, shape, size. I move methodically. I love looking at cells, in the way that a gardener loves looking at plants—not just the whole but also the parts within the parts: the leaves, the fronds, the precise smell of loam around a fern, the way the woodpecker has bored into the high branches of a tree. Blood speaks to me—but only if I pay attention.
Siddhartha Mukherjee (The Song of the Cell: An Exploration of Medicine and the New Human)
Project Mercury, the human cannonball approach, looked like a Larry Light-bulb scheme, and it gave off the funk of panic. Any pilot who went into it would no longer be a pilot. He would be a laboratory animal wired up from skull to rectum with medical sensors. The rocket pilots had fought this medical crap every foot of the way. Scott Crossfield had reluctantly allowed them to wire him for heartbeat and respiration in rocket flights but had refused to let them insert a rectal thermometer. The pilots who signed up to crawl into the Mercury capsule—the capsule, everybody noted, not the ship—would be called “astronauts.” But, in fact, they would be lab rabbits with wires up the tail and everywhere else.
Tom Wolfe (The Right Stuff)
Colt raised a brow. “That is a very good theory. Someone could have planted a tainted medicine in his home even before he began exhibiting symptoms. I’ll gather up all his medications and take them to the lab.
Kathi Daley (Message in the Mantel (The Inn at Holiday Bay, #3))
The popular image of a scientist is a disinterested and objective observer who dispassionately studies empirical data. But in reality, science is marked by fads, trends, paradigms, fashions, feuds, warring camps, petty jealousies, and die-hard beliefs. Conventional science usually reacts to new findings with disparagement. When confronted with the evidence for energy healing, one skeptic exclaimed, “I wouldn’t believe it, even if it were true!” Innovation faces daunting headwinds. The opposition to new therapies has unfortunate side effects. A group of distinguished colleagues and I analyzed US government reports on health-care innovation. We found that the average medical breakthrough takes 17 years to get from lab to patient. Even more startling, only 20% of new treatments jump this “translational gap.” The other 80% are lost forever. The result is that when we seek treatment, we are getting only one fifth of 17-year-old medicine. We would be outraged if we were forced to use a cell phone that was 17 years old, with 80% of its features disabled. But as a society, we treat this paradigm as perfectly reasonable when it comes to taking care of our precious and irreplaceable bodies. The neuroscience establishment fought the idea of neural plasticity tooth and nail. Yet eventually the evidence became too overwhelming to deny, and the weight of scientific opinion began to change. The rats that Marian Diamond studied had either an enriched or an impoverished environment. That changed their brain state. If you’re surrounded by a nurturing physical, emotional, mental, and spiritual environment, you’re in one brain state. If you’re surrounded by danger, uncertainty, and hostility, you’re in a quite different brain state.
Dawson Church (Bliss Brain: The Neuroscience of Remodeling Your Brain for Resilience, Creativity, and Joy)
I was amazed at how expensive economists thought doctors were. They instituted many economic maneuvers—de-skilling medicine onto nurses and physician assistants; computerizing medical decision-making; substituting algorithms for thinking—because they assumed that doctors were such expensive commodities. And yet doctors were not expensive, at least, not the doctors I knew. We cost no more than the nurses, the middle managers, and the information technicians, alas. Adding up all the time I spent with Mrs. Muller, the cost of her accurate diagnosis was about the same as one MRI scan, wholesale. Economists did the same thing with the other remedies of premodern medicine—good food, quiet surroundings, and the little things—treating them as expensive luxuries and cutting them out of their calculations. At Laguna Honda, for instance, while most patients were on fifteen or even twenty daily medications, many of which they didn’t need, the budget for a patient’s daily meals had been pared down to seven dollars, which could supply only the basics. I began to wonder: Had economists ever applied their standard of evidence-based medicine to their own economic assumptions? Under what conditions, with which patients and which diseases was it cost-effective to trade good food, clean surroundings, and doctor time for medications, tests, and procedures? Especially ones that patients didn’t need? Although Mrs. Muller was an impressive example of Laguna Honda’s Slow Medicine, she wasn’t the only one. Almost every patient I admitted had incorrect or outmoded diagnoses and was taking medications for them, too. Medications that required regular blood tests; caused side effects that necessitated still more medications; and put the patient at risk for adverse reactions. Typically my patients came in taking fifteen to twenty-five medications, of which they ended up needing, usually, only six or seven. And medications, even the cheapest, were expensive. Adding in the cost of side effects, lab tests, adverse reactions, and the time pharmacists, doctors, and nurses needed to prepare, order, and administer them, each medication cost something like six or seven dollars a day. So Laguna Honda’s Slow Medicine, to the extent that it led to discontinuing ten or twelve unnecessary medications, was more efficient than efficient health care by at least seventy dollars per day. I
Victoria Sweet (God's Hotel: A Doctor, a Hospital, and a Pilgrimage to the Heart of Medicine)
For example, it is only in the past few years that scientists have discovered how the brain gets rid of its waste. In other parts of the body, waste is removed in several ways, including via the lymphatic system, a system of vessels that run in parallel to the blood circulatory system. The lymphatic system picks up waste, broken-down cells, and invaders like viruses, bacteria, and fungi and carries them to the lymph glands, where the immune-system cells deal with them. Despite our well-established understanding of this process, we really didn’t know how the brain accomplished the same feat because the lymphatic system had not yet been discovered in the brain. One of the coolest studies I’ve seen in a long time was released last year by Dr. Maiken Nedergaard, co-director of the Center for Translational Neuromedicine at the University of Rochester Medical Center.21 Nedergaard’s team showed that during sleep, the size of the neurons in the brain is reduced by up to 60%. This creates a lot of space between brain cells. Then, still during sleep, a microscopic network of lymphatic vessels—the glymphatic system—clears the metabolic waste from these spaces between the neurons. This research shows that you can literally wash your brain of waste products and damage each night, if you sleep well.22 Dr. Jeffrey Iliff, who works in the same lab as Dr. Nedergaard, has shown that more than half of the amyloid beta, a protein that accumulates in the brains of patients with Alzheimer’s disease, is washed out of the brain each night via the glymphatic system. This is important because waste buildup in the brain occurs in nearly all people with neurodegenerative diseases, and this buildup may kill neurons, ultimately leading to cognitive diseases and mental deterioration. (Dr. Iliff’s TED Talk “One More Reason to Get a Good Night’s Sleep” is a great watch.)
Greg Wells (The Ripple Effect: Sleep Better, Eat Better, Move Better, Think Better)
ARE YOU GETTING ENOUGH SUNSHINE?” my doctor asked. He may have noticed my I-work-at-my-desk-all-day pallor. “I work at my desk all day,” I told him. “But I take vitamin D supplements.” He looked at my lab results. “Your calcium is on the low side of normal. Are you eating enough dark greens?” “Not to worry, Doctor. I’ll take a calcium supplement, or two.” This is how the appointment progressed in my mind as I prepared for my annual physical. I was compiling the list of medications and supplements, conscious that I was supplementing much of what the human body can normally get from a healthy diet and ten minutes of fresh air a day. How often do we try to do the same with our spiritual health? We depend on supplements—someone else’s insights, Sunday’s sermon, a brief nugget heard on the radio—as our entire spiritual intake for the week. We lean on supplements rather than a rich diet of daily Bible reading, prayer time, and reflection with Jesus. Jesus no doubt carried on a perpetual internal conversation with His Father, but He still stole away by Himself for extended times of prayer. He said we should “abide” in Him (John 15:7, NKJV), which seems more like a meal than a quick snack, doesn’t it? —CYNTHIA RUCHTI
Guideposts (Mornings with Jesus 2020: Daily Encouragement for Your Soul)
Then in 2009, Steve sequenced his own genome, in his lab, using a technology he invented himself, with postdoctoral scholar Norma Neff and Ph.D. student Dmitry Pushkarev, for just $40,000. In one week.
Euan Angus Ashley (The Genome Odyssey: Medical Mysteries and the Incredible Quest to Solve Them)
There's nothing wrong with me. This has been medically proven, once. My former insurance company stopped honoring my requests for more diagnostics and labs. A therapist gave me medicine but I didn't take it because she didn't even run tests. She based her diagnosis on my answers, on the things I told her, and I bullshitted so much I couldn't even remember which parts were genuine. How could I take a pill based on that? And what if it worked? What if my bullshit was the right-sized hole for a pill-shaped fix? I felt helpless in the face of someone helping me.
Julia Dixon Evans (How to Set Yourself on Fire)
A few weeks after my injury, when I was in the rehab center, I found someone willing to travel to the center to give me a massage. Partway through, she suggested trying something called Reiki. This is where instead of touching you, the masseuse waves their hands through the air over you to “adjust your energy fields.” You can probably tell by the way that I describe this that I think this is a bunch of BS. Does it work for some people? Of course it does. The placebo effect can work with any type of treatment or medication by providing someone with an improvement if and when they expect to get one. The nice doctor in the white lab coat gives you some pills and says, “Take two of these each morning, and your pain should feel much better.” The medication that the doctor gives you could be nothing more than sugar pills. Still, if you really believe that you’ll benefit from it, your brain finds a way to make at least some improvement come true. In double-blind studies, it’s been proven that the placebo effect can provide as much as a 32 percent improvement. Because of this, for new drugs to be approved in the US, they need to test at a level that’s higher than the 32 percent placebo level of improvement. So, if I’d believed in Reiki, then I may have experienced some benefit from it, but I don’t, so I didn’t get anything out of the treatment. That said, I think it’s interesting that when dealing with chronic pain, the temptation is to try almost anything, no matter how crazy it sounds. The hope is that maybe, just maybe, you’ll be able to get some relief from your ongoing pain.
Peter Conti (Only When I Step On It: One Man's Inspiring Journey to Hike The Appalachian Trail Alone)
murder cases are more likely to be solved when the crime occurs in private residences or bars and stores rather than in open public areas. Those cases are also more likely to be closed if detectives arrive at the crime scene within a half hour of that crime being reported and if those investigators are followed by the prompt arrival of medical examiners and crime lab technicians.
Kathryn Miles (Trailed: One Woman's Quest to Solve the Shenandoah Murders)
Natural Ways to Help Depression Depression is not one illness. Like anxiety, the pandemic spawned a whole new level of people being diagnosed with depression and placed on antidepressant medication, without ever getting a proper evaluation or trying simple fixes. Here are nine common things I do for patients before prescribing antidepressant medication. 1. Check for and (if necessary) correct thyroid hormone abnormalities. 2. Work with a nutritionally informed physician to optimize your folate, vitamin B12, vitamin D, homocysteine, and omega-3 fatty acids. I’m convinced that without doing these nutritional fixes, patients are less likely to respond to the medications. 3. Try an elimination diet for three weeks. 4. Add colorful fruits and vegetables into your diet. 5. Eliminate the ANTs (automatic negative thoughts). See days 22, 116–117. 6. Exercise—walk like you are late for 45 minutes four times a week. This has been found to be as effective as antidepressant medication.[1] 7. Add one of the following supplements to your daily routine: Saffron 30 mg/day; curcumin, not as turmeric root but as Longvida, which is much more efficiently absorbed; zinc as citrate or glycinate 30 mg (tolerable upper level is 40 mg/day for adults, 34 mg/day for adolescents, less for younger kids); or magnesium glycinate, citrate, or malate, 100–500 mg with 30 mg of vitamin B6. 8. Consume probiotics daily. 9. Try morning bright light therapy with a therapeutic lamp of 10,000 lux for 20–30 minutes. If someone comes to me with depression, I order screening labs, teach them not to believe every negative thought they have, give them basic supplements (saffron, zinc, curcumins, and omega-3s), and encourage them to exercise. Many people never need medication if they follow through with the program. If the above interventions are ineffective, I’ll try other nutraceuticals or medications targeted to their specific type of depression (take the test at brainhealthassessment.com).
Amen MD Daniel G (Change Your Brain Every Day: Simple Daily Practices to Strengthen Your Mind, Memory, Moods, Focus, Energy, Habits, and Relationships)
cause of death as “emetine cardiotoxicity due to or as a consequence of anorexia nervosa.” The anatomical summary listed pulmonary edema and congestion (usually caused by heart failure) first and anorexia second. Third was cachexia, which usually indicates extreme weight loss and an apparent lack of nutrition. The finding of emetine cardiotoxicity (ipecac poisoning) revealed that Karen had poisoned herself with ipecac syrup, a well-known emetic commonly recommended to induce vomiting in cases of overdose or poisoning. A letter detailing National Medical Services’s lab findings was composed March 23, 1983. After testing both blood and liver, it was determined that 0.48 micrograms/g emetine, “the major alkaloidal constituent of ipecac,” was present in the liver. “In the present case,” they explained, “the finding of 0.5 micrograms emetine/g, with none detected in the blood, is consistent with residua of the drug after relatively remote cessation of its chronic use.
Randy L. Schmidt (Little Girl Blue: The Life of Karen Carpenter)
intensive care units (ICUs) are physiologically fragile and unstable, generally have life-threatening conditions, and require close monitoring and rapid therapeutic interventions. They are connected to an array of equipment and monitors, and are carefully attended by the clinical staff. Staggering amounts of data are collected daily on each patient in an ICU: multi-channel waveform data sampled hundreds of times each second, vital sign time series updated each second or minute, alarms and alerts, lab results, imaging results, records of medication and fluid administration, staff notes and more.
Mit Critical Data (Secondary Analysis of Electronic Health Records)
It’s easy to have no observable health effects when you never look,” the medical director of the Lawrence Livermore lab said, back in the 1980s, after seeing how the private contractors who ran Hanford studied the matter. In her jaw-dropping 2013 book Plutopia, University of Maryland historian Kate Brown compares and contrasts American plutonium production at Hanford and its Soviet twin, Ozersk.
Michael Lewis (The Fifth Risk: Undoing Democracy)
Astonishment: these women’s military professions—medical assistant, sniper, machine gunner, commander of an antiaircraft gun, sapper—and now they are accountants, lab technicians, museum guides, teachers… Discrepancy of the roles—here and there. Their memories are as if not about themselves, but some other girls. Now they are surprised at themselves. Before my eyes history “humanizes” itself, becomes like ordinary life. Acquires a different lighting.
Svetlana Alexievich (The Unwomanly Face of War: An Oral History of Women in World War II)
The list of things that might go wrong inside the DOE was endless. The driver of a heavily armed unit assigned to move plutonium around the country was pulled over, on the job, for drunk driving. An eighty-two-year-old nun cut through the perimeter fence of a facility in Tennessee that housed weapons-grade nuclear material. A medical facility ordered a speck of plutonium for research, and a weapons-lab clerk misplaced a decimal point and FedExed the researchers a chunk of the stuff so big it should have been under armed guard—whereupon horrified medical researchers tried to FedEx it back. “At DOE even the regular scheduled meetings started with” You’re not going to believe this,’” says former chief of staff Kevin Knobloch.
Michael Lewis (The Fifth Risk: Undoing Democracy)
There is no time to discuss the fact that this horrible, horrible system is not working, or to assert that we are neither criminals or machines. There are only endless medication orders, given by exhausted people with nobody better than us to depend on.
Hope Jahren (Lab Girl)
The practical possibilities presented by a machine that could replicate human conversation, both in writing and, eventually, aloud, were intriguing and manifold: Customer service could be made more efficient. Knowledge could be imparted, languages taught. Companionship could be provided. In the event of a catastrophe, medical advice could be broadly and quickly distributed, logistical questions answered. The profitability and practicality of a conversant machine were what brought grant money into the Steiner Lab.
Liz Moore (The Unseen World)
After that, she started asking about the medical stuff.” “I hope you shut your mouth,” Brooke said. “Yes, but the questions she was asking were weird. About us again. How often did we get checked out? Did we get any special shots? Were we on special diets?” “Oh my God,” I whispered. “We’re lab rats. They’re experimenting on us. Building super wrestlers and singers who can take over the WWE and American Idol. The first steps to world domination.” “I think that’d be Canadian Wrestling Entertainment and Canadian Idol,” Daniel said. “Okay, the first very, very small step toward world domination.
Kelley Armstrong (The Gathering (Darkness Rising, #1))