Linus Pauling Quotes

I have something that I call my Golden Rule. It goes something like this: 'Do unto others twenty-five percent better than you expect them to do unto you.' … The twenty-five percent is for error.

Satisfaction of one's curiosity is one of the greatest sources of happiness in life. Linus Pauling

The best way to have a good idea is to have lots of ideas.

The way to get good ideas is to get lots of ideas, and throw the bad ones away.

Aren't the clouds beautiful? They look like big balls of cotton... I could just lie here all day, and watch them drift by... If you use your imagination, you can see lots of things in the cloud formations... What do you think you see, Linus?" "Well, those clouds up there look like the map of the British Honduras on the Caribbean... That cloud up there looks a little like the profile of Thomas Eakins, the famous painter and sculptor... And that group of clouds over there gives me the impression of the stoning of Stephen... I can see the apostle Paul standing there to one side..." "Uh huh... That's very good... What do you see in the clouds, Charlie Brown?" "Well, I was going to say I saw a ducky and a horsie, but I changed my mind!

Do unto others 20% better than you would expect them to do unto you, to correct for subjective error.

Science is the search for the truth--it is not a game in which one tries to beat his opponent, to do harm to others. We need to have the spirit of science in international affairs, to make the conduct of international affairs the effort to find the right solution, the just solution of international problems, and not an effort by each nation to get the better of other nations, to do harm to them when it is possible. I believe in morality, in justice, in humanitarianism.

The best way to get a good idea is to have a lot of ideas.

You can't have good ideas unless you have lots of ideas.

The best way to have a good idea is to have a lot of ideas.

The best way to get a good idea is to get a Lot of ideas. —LINUS PAULING

...I am not, however, militant in my atheism. The great English theoretical physicist Paul Dirac is a militant atheist. I suppose he is interested in arguing about the existence of God. I am not. It was once quipped that there is no God and Dirac is his prophet.

Do not let either the medical authorities or the politicians mislead you. Find out what the facts are, and make your own decisions about how to live a happy life and how to work for a better world.

The best way to get a good idea is to have a lot of ideas

If you want to have good ideas you must have many ideas. Most of them will be wrong, and what you have to learn is which ones to throw away.

I think that the formation of [DNA's] structure by Watson and Crick may turn out to be the greatest developments in the field of molecular genetics in recent years.

Everyone should know that most cancer research is largely a fraud, and that the major cancer research organizations are derelict in their duties to the people who support them.

Dylan's friend Linus Millberg appears out of the crowd with a cup of beer and shouts, 'Dorothy is John Lennon, the Scarecrow is Paul McCartney, the Tin Woodman is George Harrison, the Lion's Ringo.' 'Star Trek,' commands Dylan over the lousy twangy country CB's is playing between sets. 'Easy,' Linus shouts back. "Kirk's John, Spock's Paul, Bones is George, Scotty is Ringo. Or Chekov, after the first season. Doesn't matter, it's like a Scotty-Chekov-combination Ringo. Spare parts are always surplus Georges or Ringos.' 'But isn't Spock-lacks-a-heart and McCoy-lacks-a-brain like Woodman and Scarecrow? So Dorothy's Kirk?' 'You don't get it. That's just a superficial coincidence. The Beatle thing is an archetype, it's like the basic human formation. Everything naturally forms into a Beatles, people can't help it.' 'Say the types again.' 'Responsible-parent genius-parent genius-child clown-child.' 'Okay, do Star Wars.' 'Luke Paul, Han Solo John, Chewbacca George, the robots Ringo.' 'Tonight Show.' 'Uh, Johnny Carson Paul, the guest John, Ed McMahon Ringo, whatisname George.' 'Doc Severinson.' 'Yeah, right. See, everything revolves around John, even Paul. That's why John's the guest.' 'And Severinson's quiet but talented, like a Wookie.' 'You begin to understand.

She knew for a fact that being left-handed automatically made you special. Marie Curie, Albert Einstein, Linus Pauling, and Albert Schweitzer were all left-handed. Of course, no believable scientific theory could rest on such a small group of people. When Lindsay probed further, however, more proof emerged. Michelangelo, Leonardo da Vinci, M.C. Escher, Mark Twain, Hans Christian Andersen, Lewis Carrol, H.G. Wells, Eudora Welty, and Jessamyn West- all lefties. The lack of women in her research had initially bothered her until she mentioned it to Allegra. "Chalk that up to male chauvinism," she said. "Lots of left-handed women were geniuses. Janis Joplin was. All it means is that the macho-man researchers didn't bother asking.

If you want to have good ideas you must have many ideas.

Linus Pauling famously said, “If you want a good idea, start with a lot of ideas.

As Nobel laureate Linus Pauling famously said, “If you want a good idea, start with a lot of ideas.” At

Linus Pauling famously said, “If you want a good idea, start with a lot of ideas.

I saw [Linus Pauling] as a brilliant lecturer and a man with a fantastic memory, and a great, great showman. I think he was the century’s greatest chemist. No doubt about it.

In my own field, x-ray crystallography, we used to work out the structure of minerals by various dodges which we never bothered to write down, we just used them. Then Linus Pauling came along to the laboratory, saw what we were doing and wrote out what we now call Pauling's Rules. We had all been using Pauling's Rules for about three or four years before Pauling told us what the rules were.

The best way to have a good idea is to have lots of ideas

If a doctor isn't 'up' on something, he's 'down' on it.

Pauling was shocked by the freedom with which the X-ray crystallographers of the time, including particularly Astbury, played with the intimate chemical structure of their models. They seemed to think that if the atoms were arranged in the right order and about the right distance apart, that was all that mattered, that no further restrictions need to be put on them.

Wielding imaging techniques such as X-ray crystallography, which is what Rosalind Franklin used to find evidence of the structure of DNA, structural biologists try to discover the three-dimensional shape of molecules. Linus Pauling worked out the spiral structure of proteins in the early 1950s, which was followed by Watson and Crick’s paper on the double-helix structure of DNA.

So while Pauling struggled with his model, Watson and Crick turned theirs inside out, so the negative phosphorus ions wouldn’t touch. This gave them a sort of twisted ladder—the famed double helix.

I realized that more and more I was saying, 'It seems to me that we have come to the time war ought to be given up. It no longer makes sense to kill 20 million or 40 million people because of a dispute between two nations who are running things, or decisions made by the people who really are running things. It no longer makes sense. Nobody wins. Nobody benefits from destructive war of this sort and there is all of this human suffering.' And Einstein was saying the same thing of course. So that is when we decided — my wife and I — that first, I was pretty effective as a speaker. Second, I better start boning up, studying these other fields so that nobody could stand up and say, 'Well, the authorities say such and such '.

During the time that Landsteiner gave me an education in the field of immunology, I discovered that he and I were thinking about the serologic problem in very different ways. He would ask, What do these experiments force us to believe about the nature of the world? I would ask, What is the most. simple and general picture of the world that we can formulate that is not ruled by these experiments? I realized that medical and biological investigators were not attacking their problems the same way that theoretical physicists do, the way I had been in the habit of doing.

I do not know the substance of the considerations and recommendations which Dr. Szilárd proposes to submit to you,” Einstein wrote. “The terms of secrecy under which Dr. Szilárd is working at present do not permit him to give me information about his work; however, I understand that he now is greatly concerned about the lack of adequate contact between scientists who are doing this work and those members of your Cabinet who are responsible for formulating policy.”34 Roosevelt never read the letter. It was found in his office after he died on April 12 and was passed on to Harry Truman, who in turn gave it to his designated secretary of state, James Byrnes. The result was a meeting between Szilárd and Byrnes in South Carolina, but Byrnes was neither moved nor impressed. The atom bomb was dropped, with little high-level debate, on August 6, 1945, on the city of Hiroshima. Einstein was at the cottage he rented that summer on Saranac Lake in the Adirondacks, taking an afternoon nap. Helen Dukas informed him when he came down for tea. “Oh, my God,” is all he said.35 Three days later, the bomb was used again, this time on Nagasaki. The following day, officials in Washington released a long history, compiled by Princeton physics professor Henry DeWolf Smyth, of the secret endeavor to build the weapon. The Smyth report, much to Einstein’s lasting discomfort, assigned great historic weight for the launch of the project to the 1939 letter he had written to Roosevelt. Between the influence imputed to that letter and the underlying relationship between energy and mass that he had formulated forty years earlier, Einstein became associated in the popular imagination with the making of the atom bomb, even though his involvement was marginal. Time put him on its cover, with a portrait showing a mushroom cloud erupting behind him with E=mc2 emblazoned on it. In a story that was overseen by an editor named Whittaker Chambers, the magazine noted with its typical prose flair from the period: Through the incomparable blast and flame that will follow, there will be dimly discernible, to those who are interested in cause & effect in history, the features of a shy, almost saintly, childlike little man with the soft brown eyes, the drooping facial lines of a world-weary hound, and hair like an aurora borealis… Albert Einstein did not work directly on the atom bomb. But Einstein was the father of the bomb in two important ways: 1) it was his initiative which started U.S. bomb research; 2) it was his equation (E = mc2) which made the atomic bomb theoretically possible.36 It was a perception that plagued him. When Newsweek did a cover on him, with the headline “The Man Who Started It All,” Einstein offered a memorable lament. “Had I known that the Germans would not succeed in producing an atomic bomb,” he said, “I never would have lifted a finger.”37 Of course, neither he nor Szilárd nor any of their friends involved with the bomb-building effort, many of them refugees from Hitler’s horrors, could know that the brilliant scientists they had left behind in Berlin, such as Heisenberg, would fail to unlock the secrets. “Perhaps I can be forgiven,” Einstein said a few months before his death in a conversation with Linus Pauling, “because we all felt that there was a high probability that the Germans were working on this problem and they might succeed and use the atomic bomb and become the master race.”38

The way to have a good idea is to have a lot of ideas.

However, Pauling’s interest in these carotenoids and flavonoids was confined to their chemical structures and the influence of structure on optical properties; he did not address their health functions. In 1941 Pauling was diagnosed with Bright’s disease, or glomerulonephritis, which was at the time an often-fatal kidney disorder. On the advice of physicians at the Rockefeller Institute, he went to San Francisco for treatment by Thomas Addis, an innovative Stanford nephrologist. Addis prescribed a diet low in salt and protein, plenty of water, and supplementary vitamins and minerals that Pauling followed for nearly 14 years and completely recovered. This was dramatic firsthand experience of the therapeutic value of the diet. Revelations When Pauling cast about for a new research direction in the 1950s, he realized that mental illness was a significant public health problem that had not been sufficiently addressed by scientists. Perhaps his mother’s megaloblastic madness and premature death caused by B12 deficiency underlay this interest. At about this time, Pauling’s eldest son, Linus Jr., began a residency in psychiatry, which undoubtedly prompted Pauling to consider the nature of mental illness. Thanks to funding from the Ford Foundation, Pauling investigated the role of enzymes in brain function but made little progress. When he came across a copy of Niacin Therapy in Psychiatry (1962) by Abram Hoffer in 1965, Pauling was astonished to learn that simple substances needed in minute amounts to prevent deficiency diseases could have therapeutic application in unrelated diseases when given in very large amounts. This serendipitous and key event was critically responsible for Pauling’s seminal paper in his emergent medical field. Later, Pauling was especially excited by Hoffer’s observations on the survival of patients with advanced cancer who responded well to his micronutrient and dietary regimen, originally formulated to help schizophrenics manage their illness.19,20 The regimen includes large doses of B vitamins, vitamin C, vitamin E, beta-carotene, selenium, zinc, and other micronutrients. About 40 percent of patients treated adjunctively with Hoffer’s regimen lived, on average, five or more years, and about 60 percent survived four times longer than controls. These results were even better than those achieved by Scottish surgeon Ewan Cameron, Pauling’s close clinical collaborator, in Scotland. After a long and extremely productive career at Caltech,

The best way to get a good idea is to get lots of ideas. —Linus Pauling

Truth Bites

The best way to have a good idea is to have lots of ideas. Linus Pauling, winner of two Nobel Prizes

If you want to have good ideas you must have many ideas.” —Linus Pauling

AFTER the martyrdom of Paul and of Peter, Linus was the first to obtain the episcopate of the church at Rome." The actual order of the first three so-called bishops of Rome is a greatly disputed matter. The oldest tradition is that given by St. Iranaeus, according to which the order was Linus, Anencletus, Clement ... It is at least certain that Rome at that early date had no monarchical bishop, and therefore the question as to the order of these first three bishops is not a question as to a fact.

Trader Joe’s first private label food product was granola. We installed Alta Dena certified raw milk, to the disgruntlement of Southland, and within six months were the largest retailers of Alta Dena milk, both pasteurized and raw, in California. We began price-bombing five-pound cans of honey, and then all the ingredients for baking bread at home. We installed fresh orange juice squeezers in the stores, and sold fresh juice at the lowest price in town. By late in 1971, we were moving into vitamins, encouraged by my very good friend James C. Caillouette, MD. Jim spent a lot of time talking with the faculty at Cal Tech. He was convinced that Linus Pauling was on to something with his research on vitamin C. I set out to break the price on vitamin C. At one point, I think, we were doing 3 percent of sales in vitamin C! Later, Jim forwarded articles from the British medical magazine Lancet, describing how a high fiber diet could avoid colon cancer. But where could we get bran? The only stores that sold it were conventional health food stores, who sold it in bulk, something that I have always been opposed to on the grounds of hygiene. And still am! Leroy found a hippie outfit in Venice—I think it was called Mom’s Trucking—which would package the bran. But bran is a low-value product. They couldn’t afford to deliver it. Since they also packaged nuts and dried fruits, however, we somewhat reluctantly added them to the order. And that’s how Trader Joe’s became the largest retailer of nuts and dried fruits in California! Brilliant foresight! Astute market analysis! By 1989, when I left Trader Joe’s, we regularly took down 5 percent of the entire Californian pistachio crop, and we were the thirteenth largest buyer of almonds in the United States—Hershey was number one.

At Linus Pauling’s sixtieth birthday celebration, a student asked him, “Dr. Pauling, how does one go about having good ideas?” He replied, “You have a lot of ideas and throw away the bad ones.

LINUS PAULING WAS WRONG about megavitamins because he had made two fundamental errors. First, he had assumed that you cannot have too much of a good thing. Vitamins are critical to life. If people don’t get enough vitamins, they suffer various deficiency states, like scurvy (not enough vitamin C) or rickets (not enough vitamin D). The reason that vitamins are so important is that they help convert food into energy. But there’s a catch. To convert food into energy, the body uses a process called oxidation. One outcome of oxidation is the generation of something called free radicals, which can be quite destructive. In search of electrons, free radicals damage cell membranes, DNA, and arteries, including the arteries that supply blood to the heart. As a consequence, free radicals cause cancer, aging, and heart disease. Indeed, free radicals are probably the single greatest reason that we aren’t immortal. To counter the effects of free radicals, the body makes antioxidants. Vitamins—like vitamins A, C, E, and beta-carotene—as well as minerals like selenium and substances like omega-3 fatty acids all have antioxidant activity. For this reason, people who eat diets rich in fruits and vegetables, which are rich in antioxidants, tend to have less cancer, less heart disease, and live longer. Pauling’s logic to this point is clear; if antioxidants in food prevent cancer and heart disease, then eating large quantities of manufactured antioxidants should do the same thing. But Linus Pauling had ignored one important fact: Oxidation is also required to kill new cancer cells and clear clogged arteries. By asking people to ingest large quantities of vitamins and supplements, Pauling had shifted the oxidation-antioxidation balance too far in favor of antioxidation, therefore inadvertently increasing the risk of cancer and heart disease. As it turns out, Mae West aside, you actually can have too much of a good thing. (“Too much of a good thing can be wonderful,” said West, who was talking about sex, not vitamins.) Second, Pauling had assumed that vitamins and supplements ingested in food were the same as those purified or synthesized in a laboratory. This, too, was incorrect. Vitamins are phytochemicals, which means that they are contained in plants (phyto- means “plant” in Greek). The 13 vitamins (A, B1, B2, B3, B5, B6, B7, B9, B12, C, D, E, and K) contained in food are surrounded by thousands of other phytochemicals that have long and complicated names like flavonoids, flavonols, flavanones, isoflavones, anthocyanins, anthocyanidins, proanthocyanidins, tannins, isothiocyanates, carotenoids, allyl sulfides, polyphenols, and phenolic acids. The difference between vitamins and these other phytochemicals is that deficiency states like scurvy have been defined for vitamins but not for the others. But make no mistake: These other phytochemicals are important, too. And Pauling’s recommendation to ingest massive quantities of vitamins apart from their natural surroundings was an unnatural act. For example, as described in Catherine Price’s book, Vitamania, half of an apple has the antioxidant activity of 1,500 milligrams of vitamin C, even though it contains only 5.7 milligrams of the vitamin. That’s because the phytochemicals that surround vitamin C in apples enhance its effect

When a student asked Linus Pauling how he got a good idea, the double Nobel Prize winner answered: 'You have a lot of ideas and you throw away the bad ones.' Francis Crick, co-discoverer of the molecular structure of DNA, said that 'theorists in biology should realize that it is ... unlikely that they will produce a good theory at their first attempt. It is amateurs who have one big bright idea beautiful idea that they can never abandon. Professionals know that they have to produce theory after theory before they are likely to hit the jackpot.