Last Day Of 2023 Quotes

The ultimate retirement is one in which you discover who you truly are and you love that person. That, my friends, is what genuine happiness is about. Clearly, KT and I are very fortunate to be able to afford this beautiful way of life, but the lesson here is not about how wonderful our experience is. It has everything to do with the promise that awaits you in retirement. And the lesson is this: You are not defined by your work, no matter what it is or was. You are defined by who you are, how you live, and the love and respect you show to yourself and to others. There really is life after work. The ultimate retirement is one in which you wake up and greet the sunrise each day with joy. In the ultimate retirement, you find meaning in every single day. If you make the time to look inside yourself, to marvel at the wonderment of life, you will be amazed at what you discover.

hundred billion dollars being legally wagered on sports every year. “I think there’s a very high probability of more Pete Roses,” Vincent said in 2023, “and there’s going to be more corruption.

isn’t frowning on the new craze. It’s actively promoting sports gambling with corporate partnerships and in-game graphics broadcast on national television, giving viewers live betting odds of the current batter’s chances of hitting a home run in that very moment. There’s simply too much money in play not to be involved. In 2023, fans in America wagered more than one hundred billion dollars on sports, enough money that they could have pooled their cash to buy the Cincinnati Reds a hundred times over or purchase every single Major League Baseball team—and still have billions of dollars left in their pockets.

There is plenty of evidence to suggest a correlation between dementias such as Alzheimer’s disease and excessive, long-term inflammation in the body, known as chronic inflammation. A 2010 meta-analysis (an analysis of multiple papers, combining their findings) of 1,500 individuals found that those with Alzheimer’s disease tended to have raised levels of inflammatory cytokines in their blood.5 Curiously, further studies found that levels of systemic inflammation tend to be high in the early stages of the disease but not in advanced dementia.6 We also know that suffering from multiple infections increases the risk of developing dementia.7 There is also a dose-response relationship: the more infections (regardless of type), the higher the risk of dementia.8 An intriguing study, published by researchers at Stanford University in 2023, points the finger at one specific infectious agent: the varicella-zoster virus.9 This is the form of herpes virus we met in the last chapter, which has the dishonourable role of causing both chickenpox and shingles. The team analysed data from the National Health Service in Wales, because in late 2013 the Welsh Government enacted a health intervention that doubles up as a large natural experiment: they rolled out the shingles vaccine to people born on or after 2 September 1933. Over a seven-year follow-up comparing the vaccinated to the unvaccinated, they found that the shingles vaccine reduced the chance of developing dementia by around 20 per cent. While these are early days – and this study raises as many questions as it answers – it is looking likely that infectious agents are responsible for some proportion of dementia cases. Non-infectious inflammatory stimuli also increase the risk of developing dementia, from surgical operations to chronic autoimmune diseases.10 A remarkable link between systemic inflammation and dementia was uncovered in 2016, when researchers at the University of Southampton found that those with gum inflammation (periodontitis) had a six-fold increased risk of developing Alzheimer’s disease over a six-month period.11 In summary: it appears that inflammation in the body can drive the development of Alzheimer’s disease.