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And though David never mentioned it in his writing, his work owed a clear debt to the landmark research of another NIMH psychologist, John B. Calhoun, who’d studied rat populations since 1946. Calhoun reported that rats in confined groups—even without drugs—became uncharacteristically aggressive. They’d erupt in rape, murder, cannibalism, and infanticide. A dominant male rat emerged in the “behavioral sink”—Calhoun’s term for his aggregated rat cultures—subjugating other males into a tribe of cowering, enfeebled followers and organizing female rats into a “harem” of sex slaves. The strangest group to emerge was “the probers”: “hypersexualized” male rats that stalked and raped both males and females, and often cannibalized their young. The probers would commit “frenzied” and “berserk” attacks against rat families sleeping in their burrows, leaving the remains of half-eaten victims. Again, no drugs were involved here; the probers emerged simply as a result of their confinement. They deferred only to the dominant male rat, fleeing if he caught sight of them.
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Tom O'Neill (Chaos: Charles Manson, the CIA, and the Secret History of the Sixties)