Immune System Related Quotes

You cannot trade the courage needed to live every moment for immunity from life's sorrows. We may say we know this but ours is the culture of the deal-making mind. From infancy, we have breathed in the belief that there is always a deal to be made, a bargain to be struck. Eventually, we believe, if we do the right thing, if we are good enough, clever enough, sincere enough, work hard enough, we will be rewarded. There are different verses to this song - if you are sorry for your sins and try hard not to sin again, you will go to heaven; if you do your daily practise, clean up your diet, heal your inner child, ferret out all your emotional issue's, focus your intent, come into alignment with the world around you, hone your affirmations, find and listen to the voice of your higher self, you will be rewarded with vibrant health, abundant prosperity, loving relations and inner peace - in other words, heaven! We know that what we do and how we think affects the quality of our lives. Many things are clearly up to us. And many others are not. I can see no evidence that the universe works on a simple meritocratic system of cause and effect. Bad things happen to good people - all the time. Monetary success does come to some who do not do what they love, as well as to some who are unwilling or unable to see the harm they do to the planet or others. Illness and misfortune come to some who follow their soul's desire. Many great artist's have been poor. Great teachers have lived in obscurity. My invitation, my challenge to you here, is to journey into a deeper intimacy with the world and your life without any promise of safety or guarantee of reward beyond the intrinsic value of full participation.

The gut is the seat of all feeling. Polluting the gut not only cripples your immune system, but also destroys your sense of empathy, the ability to identify with other humans.

The gut is the seat of all feeling. Polluting the gut not only cripples your immune system, but also destroys your sense of empathy, the ability to identify with other humans. Bad bacteria in the gut creates neurological issues. Autism can be cured by detoxifying the bellies of young children. People who think that feelings come from the heart are wrong. The gut is where you feel the loss of a loved one first. It's where you feel pain and a heavy bulk of your emotions. It's the central base of your entire immune system. If your gut is loaded with negative bacteria, it affects your mind. Your heart is the seat of your conscience. If your mind is corrupted, it affects your conscience. The heart is the Sun. The gut is the Moon. The pineal gland is Neptune, and your brain and nervous system (5 senses) are Mercury. What affects the moon or sun affects the entire universe within. So, if you poison the gut, it affects your entire nervous system, your sense of reasoning, and your senses.

Health is normal. The human body is a self-repairing, self-defending, self-healing marvel. Disease is relatively difficult to induce, considering the body's powerful immune system. However, this complicated and delicate machinery can be damaged if fed the wrong fuel during the formative years. ... Healthy living with nutritional excellence throughout life can slow the decline of aging. It can prevent the years and years of suffering in ill health that is so common today as people get older and become dependent on medical treatments, drugs, and surgery. Nutritional excellence is the only real fountain of youth.

Irwin demonstrated that a single night of four hours of sleep—such as going to bed at three a.m. and waking up at seven a.m.—swept away 70 percent of the natural killer cells circulating in the immune system, relative to a full eight-hour night of sleep. That is a dramatic state of immune deficiency to find yourself facing, and it happens quickly, after essentially one “bad night” of sleep.

Stress can be bad for you. We no longer die of smallpox or the plague and instead die of stress-related diseases of lifestyle, like heart disease or diabetes, where damage slowly accumulates over time. It is understood how stress can cause or worsen disease or make you more vulnerable to other risk factors. Much of this is even understood on the molecular level. Stress can even cause your immune system to abnormally target hair follicles, causing your hair to turn gray.

Many age-related diseases are caused by an immune system out of balance. Excessive or unnecessary inflammation accelerates heart disease, bone loss,

In recent years, there has been an explosion of research into meditation, which has been shown to: • Reduce blood pressure • Boost recovery after the release of the stress hormone cortisol • Improve immune system functioning and response • Slow age-related atrophy of the brain • Mitigate the symptoms of depression and anxiety

Socrates tried to soothe us, true enough. He said there were only two possibilities. Either the soul is immortal or, after death, things would be again as blank as they were before we were born. This is not absolutely comforting either. Anyway it was natural that theology and philosophy should take the deepest interest in this. They owe it to us not to be boring themselves. On this obligation they don’t always make good. However, Kierkegaard was not a bore. I planned to examine his contribution in my master essay. In his view the primacy of the ethical over the esthetic mode was necessary to restore the balance. But enough of that. In myself I could observe the following sources of tedium: 1) The lack of a personal connection with the external world. Earlier I noted that when I was riding through France in a train last spring I looked out of the window and thought that the veil of Maya was wearing thin. And why was this? I wasn’t seeing what was there but only what everyone sees under a common directive. By this is implied that our worldview has used up nature. The rule of this view is that I, a subject, see the phenomena, the world of objects. They, however, are not necessarily in themselves objects as modern rationality defines objects. For in spirit, says Steiner, a man can step out of himself and let things speak to him about themselves, to speak about what has meaning not for him alone but also for them. Thus the sun the moon the stars will speak to nonastronomers in spite of their ignorance of science. In fact it’s high time that this happened. Ignorance of science should not keep one imprisoned in the lowest and weariest sector of being, prohibited from entering into independent relations with the creation as a whole. The educated speak of the disenchanted (a boring) world. But it is not the world, it is my own head that is disenchanted. The world cannot be disenchanted. 2) For me the self-conscious ego is the seat of boredom. This increasing, swelling, domineering, painful self-consciousness is the only rival of the political and social powers that run my life (business, technological-bureaucratic powers, the state). You have a great organized movement of life, and you have the single self, independently conscious, proud of its detachment and its absolute immunity, its stability and its power to remain unaffected by anything whatsoever — by the sufferings of others or by society or by politics or by external chaos. In a way it doesn’t give a damn. It is asked to give a damn, and we often urge it to give a damn but the curse of noncaring lies upon this painfully free consciousness. It is free from attachment to beliefs and to other souls. Cosmologies, ethical systems? It can run through them by the dozens. For to be fully conscious of oneself as an individual is also to be separated from all else. This is Hamlet’s kingdom of infinite space in a nutshell, of “words, words, words,” of “Denmark’s a prison.

Honest concern for others is the key factor in improving our day-to-day lives. When you are warm-hearted, there is no room for anger, jealousy, or insecurity. A calm mind and self-confidence are the basis for happy and peaceful relations with each other. Healthy, happy families and a healthy, peaceful nation are dependent on warm-heartedness. Some scientists have observed that constant anger and fear eat away at our immune system, whereas a calm mind strengthens it. We have to see how we can fundamentally change our education system so that we can train people to develop warm-heartedness early on in order to create a healthier society. I don't mean we need to change the whole system—just improve it. We need to encourage an understanding that inner peace comes from relying on human values like love, compassion, tolerance, and honesty, and that peace in the world relies on individuals finding inner peace. —HIS HOLINESS, THE DALAI LAMA

Ionizing radiation takes three principal forms: alpha particles, beta particles, and gamma rays. Alpha particles are relatively large, heavy, and slow moving and cannot penetrate the skin; even a sheet of paper could block their path. But if they do manage to find their way inside the body by other means—if swallowed or inhaled—alpha particles can cause massive chromosomal damage and death. Radon 222, which gathers as a gas in unventilated basements, releases alpha particles into the lungs, where it causes cancer. Polonium 210, a powerful alpha emitter, is one of the carcinogens in cigarette smoke. It was also the poison slipped into the cup of tea that killed former FSB agent Alexander Litvinenko in London in 2006. Beta particles are smaller and faster moving than alpha particles and can penetrate more deeply into living tissue, causing visible burns on the skin and lasting genetic damage. A piece of paper won’t provide protection from beta particles, but aluminum foil—or separation by sufficient distance—will. Beyond a range of ten feet, beta particles can cause little damage, but they prove dangerous if ingested in any way. Mistaken by the body for essential elements, beta-emitting radioisotopes can become fatally concentrated in specific organs: strontium 90, a member of the same chemical family as calcium, is retained in the bones; ruthenium is absorbed by the intestine; iodine 131 lodges particularly in the thyroid of children, where it can cause cancer. Gamma rays—high-frequency electromagnetic waves traveling at the speed of light—are the most energetic of all. They can traverse large distances, penetrate anything short of thick pieces of concrete or lead, and destroy electronics. Gamma rays pass straight through a human being without slowing down, smashing through cells like a fusillade of microscopic bullets. Severe exposure to all ionizing radiation results in acute radiation syndrome (ARS), in which the fabric of the human body is unpicked, rearranged, and destroyed at the most minute levels. Symptoms include nausea, vomiting, hemorrhaging, and hair loss, followed by a collapse of the immune system, exhaustion of bone marrow, disintegration of internal organs, and, finally, death.

You can do your entire career on one cell type and it’s more likely you keep your job by getting grants,” Casadevall told me. “There is not even pressure to integrate. In fact, if you write a grant proposal about how the B cell is integrating with the macrophage [a basic interaction of the immune system],* there may be no one to review it. If it goes to the macrophage people, they say, ‘Well, I don’t know anything about it. Why B cells?’ The system maintains you in a trench. You basically have all these parallel trenches, and it’s very rare that anybody stands up and actually looks at the next trench to see what they are doing, and often it’s related.

Sexual reproduction is thus a costly investment that has to pay for itself in the short run. The details of theory and experiment on this topic are fascinating (see, e.g., Maynard Smith, 1978; Ridley, 1993), but for our purposes a few highlights from the currently front-running theory are most instructive: sex (in vertebrates like us, at least) pays for itself by making our offspring relatively inscrutable to the parasites we endow them with from birth. Parasites have short lifespans compared with their hosts, and typically reproduce many times during their host’s lifetime. Mammals, for instance, are hosts to trillions of parasites. (Yes, right now, no matter how healthy and clean you are, there are trillions of parasites of thousands of different species inhabiting your gut, your blood, your skin, your hair, your mouth, and every other part of your body. They have been rapidly evolving to survive against the onslaught of your defenses since the day you were born.) Before a female can mature to reproductive age, her parasites evolve to fit her better than any glove. (Meanwhile, her immune system evolves to combat them, a standoff—if she is healthy—in an ongoing arms race.) If she gave birth to a clone, her parasites would leap to it and find themselves at home from the outset. They would be already optimized to their new surroundings. If instead she uses sexual reproduction to endow her offspring with a mixed set of genes (half from her mate), many of these genes—or, more directly, their products, in the offspring’s internal defenses—will be alien or cryptic to the ship-jumping parasites. Instead of home sweet home, the parasites will find themselves in terra incognita. This gives the offspring a big head start in the arms race.

It may seem paradoxical to claim that stress, a physiological mechanism vital to life, is a cause of illness. To resolve this apparent contradiction, we must differentiate between acute stress and chronic stress. Acute stress is the immediate, short-term body response to threat. Chronic stress is activation of the stress mechanisms over long periods of time when a person is exposed to stressors that cannot be escaped either because she does not recognize them or because she has no control over them. Discharges of nervous system, hormonal output and immune changes constitute the flight-or-fight reactions that help us survive immediate danger. These biological responses are adaptive in the emergencies for which nature designed them. But the same stress responses, triggered chronically and without resolution, produce harm and even permanent damage. Chronically high cortisol levels destroy tissue. Chronically elevated adrenalin levels raise the blood pressure and damage the heart. There is extensive documentation of the inhibiting effect of chronic stress on the immune system. In one study, the activity of immune cells called natural killer (NK) cells were compared in two groups: spousal caregivers of people with Alzheimer’s disease, and age- and health-matched controls. NK cells are front-line troops in the fight against infections and against cancer, having the capacity to attack invading micro-organisms and to destroy cells with malignant mutations. The NK cell functioning of the caregivers was significantly suppressed, even in those whose spouses had died as long as three years previously. The caregivers who reported lower levels of social support also showed the greatest depression in immune activity — just as the loneliest medical students had the most impaired immune systems under the stress of examinations. Another study of caregivers assessed the efficacy of immunization against influenza. In this study 80 per cent among the non-stressed control group developed immunity against the virus, but only 20 per cent of the Alzheimer caregivers were able to do so. The stress of unremitting caregiving inhibited the immune system and left people susceptible to influenza. Research has also shown stress-related delays in tissue repair. The wounds of Alzheimer caregivers took an average of nine days longer to heal than those of controls. Higher levels of stress cause higher cortisol output via the HPA axis, and cortisol inhibits the activity of the inflammatory cells involved in wound healing. Dental students had a wound deliberately inflicted on their hard palates while they were facing immunology exams and again during vacation. In all of them the wound healed more quickly in the summer. Under stress, their white blood cells produced less of a substance essential to healing. The oft-observed relationship between stress, impaired immunity and illness has given rise to the concept of “diseases of adaptation,” a phrase of Hans Selye’s. The flight-or-fight response, it is argued, was indispensable in an era when early human beings had to confront a natural world of predators and other dangers. In civilized society, however, the flight-fight reaction is triggered in situations where it is neither necessary nor helpful, since we no longer face the same mortal threats to existence. The body’s physiological stress mechanisms are often triggered inappropriately, leading to disease. There is another way to look at it. The flight-or-fight alarm reaction exists today for the same purpose evolution originally assigned to it: to enable us to survive. What has happened is that we have lost touch with the gut feelings designed to be our warning system. The body mounts a stress response, but the mind is unaware of the threat. We keep ourselves in physiologically stressful situations, with only a dim awareness of distress or no awareness at all.

Kircher’s system shows certain affinities with our series of quaternios. Thus the Second Monad is a duality consisting of opposites, corresponding to the angelic world that was split by Lucifer’s fall. Another significant analogy is that Kircher conceives his schema as a cycle set in motion by God as the prime cause, and unfolding out of itself, but brought back to God again through the activity of human understanding, so that the end returns once more to the beginning. This, too, is an analogy of our formula. The alchemists were fond of picturing their opus as a circulatory process, as a circular distillation or as the uroboros, the snake biting its own tail, and they made innumerable pictures of this process. Just as the central idea of the lapis Philosophorum plainly signifies the self, so the opus with its countless symbols illustrates the process of individuation, the step-by-step development of the self from an unconscious state to a conscious one. That is why the lapis, as prima materia, stands at the beginning of the process as well as at the end.113 According to Michael Maier, the gold, another synonym for the self, comes from the opus circulatorium of the sun. This circle is “the line that runs back upon itself (like the serpent that with its head bites its own tail), wherein that eternal painter and potter, God, may be discerned.”114 In this circle, Nature “has related the four qualities to one another and drawn, as it were, an equilateral square, since contraries are bound together by contraries, and enemies by enemies, with the same everlasting bonds.” Maier compares this squaring of the circle to the “homo quadratus,” the four-square man, who “remains himself” come weal come woe.115 He calls it the “golden house, the twicebisected circle, the four-cornered phalanx, the rampart, the city wall, the four-sided line of battle.”116 This circle is a magic circle consisting of the union of opposites, “immune to all injury.

The Western medical model — and I don't mean the science of it, I mean the practice of it, because the science is completely at odds with the practice — makes two devastating separations. First of all we separate the mind from the body, we separate the emotions from the physiology. So we don't see how the physiology of people reflects their lifelong emotional experience. So we separate the mind from the body, which is not something that traditional medicine has done, I mean, Ayuverdic or Chinese medicine or shamanic tribal cultures and medicinal practices throughout the world have always recognized that mind and body are inseparable. They intuitively knew it. Many Western practitioners have known this and even taught it, but in practice we ignore it. And then we separate the individual from the environment. The studies are clear, for example, that when people are emotionally isolated they tend to get sick more quickly and they succumb more rapidly to their disease. Why? Because people's physiology is completely related to their psychological, social environment and when people are isolated and alone their stress levels are much higher because there's nothing there to help them moderate their stress. And physiologically it is straightforward, you know, it takes a five-year-old kid to understand it. However because in practice we separate them... when somebody shows up with an inflamed joint, all we do is we give them an anti-inflammatory or because the immune system is hyperactive and is attacking them we give them a medication to suppress their immune system or we give them a stress hormone like cortisol or one of its analogues, to suppress the inflammation. But we never ask: "What does this manifest about your life?", "What does this say about your relationships?", "How stressful is your job?", "To what extent do you lack control in your life?", "Where are you not authentic?", "How are you trying to work so hard to meet your attachment needs by suppressing yourself?" (because that is what you learn to do as a kid). Then we do all this research that has to do with cell biology, so we keep looking for the cause of cancer in the cell. Now there's a wonderful quote in the New York Times a couple of years ago they did a series on cancer and somebody said: "Looking for the cause of cancer inside the individual cell is like trying to understand a traffic jam by studying the internal combustion engine." We will never understand it, but we spend hundreds of billions of dollars a year looking for the cause of cancer inside the cell, not recognizing that the cell exists in interaction with the environment and that the genes are modulated by the environment, they are turned on and off by the environment. So the impact of not understanding the unity of emotions and physiology on one hand and in the other hand the relationship between the individual and the environment.. in other words.. having a strictly biological model as opposed to what has been called a bio-psycho-social, that recognizes that the biology is important, but it also reflects our psychological and social relationships. And therefore trying to understand the biology in isolation from the psychological and social environment is futile. The result is that we are treating people purely through pharmaceuticals or physical interventions, greatly to the profit of companies that manufacture pharmaceuticals and which fund the research, but it leaves us very much in the dark about a) the causes and b) the treatment, the holistic treatment of most conditions. So that for all our amazing interventions and technological marvels, we are still far short of doing what we could do, were we more mindful of that unity. So the consequences are devastating economically, they are devastating emotionally, they are devastating medically.

Many people confuse “chronic fatigue” (which is a symptom of many chronic conditions, including rheumatoid arthritis, fibromyalgia, or lupus) or “general tiredness” (which is lifestyle-related), with the specific illness “chronic fatigue syndrome” (ME/CFS). To clarify the differences, here are some of the major symptoms of ME/CFS: - unexplained physical and mental fatigue for an extended period of time - post-exertional malaise (meaning an inappropriate loss of physical and mental stamina and a worsening of symptoms after any effort) - sleep dysfunction - pain - neurological/cognitive manifestations - autonomic manifestations, such as orthostatic intolerance - neuroendocrine symptoms, such as subnormal body temperature - immune system changes, such as recurrent flu-like symptoms.

Chasing tax cheats using normal procedures was not an option. It would take decades just to identify anything like the majority of them and centuries to prosecute them successfully; the more we caught, the more clogged up the judicial system would become. We needed a different approach. Once Danis was on board a couple of days later, together we thought of one: we would extract historical and real-time data from the banks on all transfers taking place within Greece as well as in and out of the country and commission software to compare the money flows associated with each tax file number with the tax returns of that same file number. The algorithm would be designed to flag up any instance where declared income seemed to be substantially lower than actual income. Having identified the most likely offenders in this way, we would make them an offer they could not refuse. The plan was to convene a press conference at which I would make it clear that anyone caught by the new system would be subject to 45 per cent tax, large penalties on 100 per cent of their undeclared income and criminal prosecution. But as our government sought to establish a new relationship of trust between state and citizenry, there would be an opportunity to make amends anonymously and at minimum cost. I would announce that for the next fortnight a new portal would be open on the ministry’s website on which anyone could register any previously undeclared income for the period 2000–14. Only 15 per cent of this sum would be required in tax arrears, payable via web banking or debit card. In return for payment, the taxpayer would receive an electronic receipt guaranteeing immunity from prosecution for previous non-disclosure.17 Alongside this I resolved to propose a simple deal to the finance minister of Switzerland, where so many of Greece’s tax cheats kept their untaxed money.18 In a rare example of the raw power of the European Union being used as a force for good, Switzerland had recently been forced to disclose all banking information pertaining to EU citizens by 2017. Naturally, the Swiss feared that large EU-domiciled depositors who did not want their bank balances to be reported to their country’s tax authorities might shift their money before the revelation deadline to some other jurisdiction, such as the Cayman Islands, Singapore or Panama. My proposals were thus very much in the Swiss finance minister’s interests: a 15 per cent tax rate was a relatively small price to pay for legalizing a stash and allowing it to remain in safe, conveniently located Switzerland. I would pass a law through Greece’s parliament that would allow for the taxation of money in Swiss bank accounts at this exceptionally low rate, and in return the Swiss finance minister would require all his country’s banks to send their Greek customers a friendly letter informing them that, unless they produced the electronic receipt and immunity certificate provided by my ministry’s web page, their bank account would be closed within weeks. To my great surprise and delight, my Swiss counterpart agreed to the proposal.19

Exactly how and why sleep disruption is linked to certain forms of cancer is also becoming clear. Part of the problem relates back to the agitating influence of the sympathetic nervous system as it is forced into overdrive by a lack of sleep. Ramping up the body’s level of sympathetic nervous activity will provoke an unnecessary and sustained inflammation response from the immune system. When faced with a real threat, a brief spike of sympathetic nervous system activity will often trigger a similarly transient response from inflammatory activity—one that is useful in anticipation of potential bodily harm (think of a physical tussle with a wild animal

Instead, we often use guanfacine, a nonstimulant that was originally developed to treat high blood pressure but has also been used to treat ADHD. Guanfacine targets specific circuits in the prefrontal cortex where adrenaline and noradrenaline exert their action, improving impulsiveness and concentration, even in situations of high stress. While I felt good about taking a more systemic approach, like the doctors who first began to suspect that a compromised immune system was behind HIV/AIDS, I was working on a medical frontier. There wasn’t (and still isn’t) a clear set of diagnostic criteria or a blood test for toxic stress, and there is no drug cocktail to prescribe. My biggest guide for what symptoms might be toxic stress–related was the ACE Study itself, but I knew that the number of diseases and conditions it accounted for might just be the tip of the iceberg. After all,

the answer is relatively simple: People avoid the public health system because it does not work well. This could also explain why other services that are provided through the government system, like immunizations and antenatal checks for prospective mothers, are underused.

It is also unclear why physical inactivity might be a mismatch for the immune system apart from the generally negative effects of sedentariness on overall health and levels of stress (which, as we have seen, depresses the immune system). One possibility is that because heading off to the bush to hunt and gather potentially made our ancestors more likely to encounter pathogens, our immune systems evolved to compensate by ramping up our defenses when we are active. A related possible explanation stems from the stingy way our bodies use calories. The fatigue we experience when fighting a cold is a reminder that the immune system is often energetically costly. As a result, maybe our immune systems evolved to be less vigilant when they are less needed. For hunter-gatherers, unlike most industrial people, those times might have been when they were less physically active and thus less likely to be exposed to pathogens.

FAMILY VALUES If you start watching pigeons, one of the first things you’ll notice is that you never see a chick. Like some mythical beast, these birds reveal themselves to humans only after reaching maturity. There are two good reasons for this: First, pigeons are good at hiding their nests; and second, the young birds—called squabs—stay in the nest until they lose the obvious indicators of youth. They are able to do this because mother and father pigeon work together to provide for their young. This equality in parenting extends to milk production: Both males and females secrete a cheesy yellow milk into the crop, a food-storage pouch partway down the throat. I had thought that milk belonged exclusively to mammals; it’s our defining characteristic, so important that we are named for it—“mammal” comes from the Latin mamma, meaning breast. Pigeons are more closely related to dinosaurs than mammals. Like breast milk, pigeon milk contains antibodies and immune-system regulators. Like breast milk, it is stimulated by the hormone prolactin; in fact, scientists discovered prolactin while studying pigeons. Despite the similarities, mammal milk isn’t a relative of pigeon milk. Instead, it is an example of

And indeed, many trauma-related health problems are dismissed, missed, and misunderstood. But once you understand more about neuroscience, and how our senses and brain translate experience into “biological” activity, the artificial distinctions disappear. If you understand the neurobiology of trauma, you know that a physical “abnormality” is causing the abdominal pain seen with sensitized dissociation. You begin to see that a person’s “worldview” can change their immune system, and that a positive conversation with a friend can influence how a patient’s heart or lungs function that day. The interconnectedness becomes clear.

For reasons that are just being sorted out, in some people the immune system decides that the cells in the pancreas that secrete insulin are, in fact, foreign invaders and attacks them (such “autoimmune” diseases will be discussed in chapter 8). This destroys those cells, leaving the person with little ability to secrete insulin.

The idea that depression and all of its relatives are manifestations of glitches in the immune system and inflammatory pathways—not a neurochemical deficiency disorder—is a topic we will explore at length throughout this book. This

stimulation of our immune system in early life and the development of immunological problems later on has led to the “hygiene hypothesis”: that clean upbringings, relatively free of parasites and infectious agents, do not lead to development of a healthy immune system

If you’re like most people, a string of nerve-racking incidents keeps you in fight-or-flight response—and out of homeostasis—a large part of the time. Maybe the car cutting you off is the only actual life-threatening situation you encounter all day, but the traffic on the way to work, the pressure of preparing for a big presentation, the argument you had with your spouse, the credit-card bill that came in the mail, the crashing of your computer hard drive, and the new gray hair you noticed in the mirror keep the stress hormones circulating in your body on a near-constant basis. Between remembering stressful experiences from the past and anticipating stressful situations coming up in your future, all these repetitive short-term stresses blur together into long-term stress. Welcome to the 21st-century version of living in survival mode. In fight-or-flight mode, life-sustaining energy is mobilized so that the body can either run or fight. But when there isn’t a return to homeostasis (because you keep perceiving a threat), vital energy is lost in the system. You have less energy in your internal environment for cell growth and repair, long-term building projects on a cellular level, and healing when that energy is being channeled elsewhere. The cells shut down, they no longer communicate with one another, and they become “selfish.” It’s not time for routine maintenance (let alone for making improvements); it’s time for defense. It’s every cell for itself, so the collective community of cells working together becomes fractured. The immune and endocrine systems (among others) become weakened as genes in those related cells are compromised when informational signals from outside the cells are turned off. It’s like living in a country where 98 percent of the resources go toward defense, and nothing is left for schools, libraries, road building and repair, communication systems, growing of food, and so on. Roads develop potholes that aren’t fixed. Schools suffer budget cuts, so students wind up learning less. Social welfare programs that took care of the poor and the elderly have to close down. And there’s not enough food to feed the masses. Not surprisingly, then, long-term stress has been linked to anxiety, depression, digestive problems, memory loss, insomnia, hypertension, heart disease, strokes, cancer, ulcers, rheumatoid arthritis, colds, flu, aging acceleration, allergies, body pain, chronic fatigue, infertility, impotence, asthma, hormonal issues, skin rashes, hair loss, muscle spasms, and diabetes, to name just a few conditions (all of which, by the way, are the result of epigenetic changes). No organism in nature is designed to withstand the effects of long-term stress.

Excessive chemicals eventually inhibit your immune system (the defence against infections and illnesses) making you vulnerable to viruses of every shape and size. They will lower the production of serotonin (making you feel listless and joyless as in depression) and can eventually, if they remain virulent, cause heart disease, hardening of the arteries, type 2 diabetes and certain cancers. Inadvertently stress will destroy you both mentally and physically unless you change the way you think about it and relate to it. With

Research also shows that sugar itself can impair the function of immunity-related phagocytes (immune system cells that remove bacteria or viruses from the bloodstream) for at least five hours after ingestion.

More often than not, focusing on stress, pain and chaos in our lives creates even more stress, pain and chaos for us. Here’s what I’ve experienced, and my guess is that it’s happened to you as well: Whenever I am focused on how difficult my life is, I begin to feel overwhelmed, stressed, depressed, and worried. These emotions, in turn, influence my productivity, actions and choices. They may even change my sleeping patterns and compromise my immune system. Sooner or later they begin to interfere with my relationships with family and friends. They even hinder the way I worship or approach God. As these emotions continue to influence how I live, cope, function, and relate to those around me, they can even impact my finances and long-term security.

state of calm produced by meditation, yoga, and breathing exercises—actually switched on genes that are related to augmenting our immune system, reducing inflammation, and fighting a range of conditions from arthritis to high blood pressure to diabetes. So with all these results, it’s no surprise that, according to another study, meditation correlates to reduced yearly medical costs. It

The majority of genes in the [MHC (Mean Histocompatibility Complex)] class I region are not involved in the immune system; neither do the class I genes form as a compact cluster as the class II genes. Whereas genes encoding class II molecules are only present in the class II region of the HLA [(Human Leukocyte Antigen) complex], genes encoding class I molecules and related class I-like molecules are found on several different chromosomes. A further difference is that HLA class II molecules are dedicated components of adaptive immunity that serve only to present antigen to T cells, whereas HLA class I and class I-like molecules encompass a broader range of functions, including uptake of IgG in the gut, regulation of iron metabolism, and regulation of NK [(Natural Killer)]-cell function in the innate immune response. Together, these genetic and functional differences show that MCH class I is the older form of MHC molecule and that MHC class II evolved more recently from MHC class I. Consistent with this proposition, MHC class II is not always essential for a vertebrate immune system, unlike class I. The Atlantic cod manages very well with only MHC class I genes.

And that’s when I started developing bald spots. Bald spots developed randomly all over my head. I couldn’t hide them and had to put up with people looking at me as though I were an attraction at a freak show. I looked into it and learned that stress can sometimes cause bald patches. This is caused when the immune system begins to attack hair follicles. Work related stress was causing me to lose hair!

Jason could tell a yarn. He could hardly talk without telling a yarn; according to his zealous world view, every day was an adventure. He would relate his experiences like a combination of a bard, radio talk-show host, and bawdy

Excessive body acidity is regarded to become the first step in premature aging, vision and memory problems, wrinkling, age spots, hormone system failure, and a slew of other age-related issues. In addition, body acidity is linked to practically most diseases.

A person’s “worldview” can change their immune system, and…a positive conversation with a friend can influence how a patient’s heart or lungs function that day. The interconnectedness becomes clear…everything matters…belonging is biology, and disconnection destroys our health. Trauma is disconnecting, and that impacts every system in our body...To this day, the role that trauma and developmental adversity play in mental and physical health remains underappreciated. children and adults with developmental trauma frequently experience chronic abdominal pain, headaches, chest pain, fainting, and seizure-like episodes-all very common symptoms related to a sensitized stress response.

TO STRENGTHEN OUR IMMUNE SYSTEM AND COMBAT ITS AGE-RELATED DECLINE: The peptide thymosin alpha-1 (Zadaxin): As we age, our thymus gland gradually turns into fat tissue and stops producing the robust battalions of T cells that fight off infections or eliminate rogue cancer cells. If we had to choose a single peptide to help address immunological aging, according to Dr. Lopez, thymosin alpha-1 might be the one. TA-1 has proven its ability to stimulate the immune system in both animal and human studies.

Throat Let your fingers touch each other as you cup your hands on the bottom of the throat. Be gentle, and hold on to your hands, but do not touch your throat. Helping the thyroid and parathyroid gland, vocal cords, larynx, and lymph nodes, this hand position handles the throat (fifth) chakra that regulates neck and chest. This is the seat of communication and expression. Using therapy to help the patient speak, speak their minds, talk for themselves, and tell their reality. It's also perfect for writer’s block! Collarbone Place your hands with your fingers pointing to the middle of your chest on the sides of your arms. This position gives Reiki to the area of the thymus between the chakras of the throat and the neck. For immune function, the thymus gland is essential. Place yourself behind or on the recipient's side for this next position (it all depends on your height logistics, their height, and how far you can stretch!). Back of the neck and front of the heart Put your left hand under the neck area and your right hand over the top of the heart area of the middle. This role incorporates heart and back care of the heart. They address two regions simultaneously: the chakra of the throat and the chakra of the heart, which helps to express one's heart or to say one's reality. This is a good position to handle high blood pressure; any position on the neck actually helps reduce high blood pressure. Heart Place the hands in a T, a hand positioned horizontally above the breasts, and a hand placed vertically between the breasts. Treating the heart (fourth) chakra governs everything related to the circulatory system, including the pulse, veins, and arteries; the lungs (related to the chakras of the heart and throat); the breasts; and the thymus. Opening Reiki's heart chakra increases the supply of affection, air, and nourishment that can be received and offered. The recipient feels acceptance and a sense of love and compassion when the heart chakra is free and moving.

It even appears that, during periods of excessive stress, the immune system's failure to fight off disease may be related to the whole organism's internal lack of, or confusion, of meaning. Indeed, if the meaning of the body is taken to be its intelligent, coordinated activity in health, then disease is a degeneration or breakdown in meaning.

The sources of covert racial bias are found all around us and are parts of US history. They are not particular to the criminal justice system, but given the powerful effects of race on criminal justice matters, and the over-representation of minorities in the criminal justice system, there should be no surprise that many associate crime with minorities, particularly young males. Crucially, according to the accumulated social psychological literature, no one growing up in mainstream US culture would be immune to these pressures (see for example Gillian and Iyengar 2000). Furthermore, within the police profession, there is ample reason to expect that such biases may be especially strong. In particular, as relates to the decision to shoot or not to shoot a hypothetical suspect in an ambiguous experimental setting, the black suspects are typically shot in a higher percentage of the cases than an identically situated white suspect (see for example Correll et al. 2002; Correll et al. 2007; Correll 2009).

Rhinoviruses infect relatively few cells, causing little real harm. So why can they cause such miserable experiences? We have only ourselves to blame. Infected cells release signaling molecules, called cytokines, which attract nearby immune cells. Those immune cells then make us feel awful. They create inflammation that triggers a scratchy feeling in the throat and leads to the production of a lot of mucus around the site of the infection. In order to recover from a cold, we have to wait not only for the immune system to wipe out the virus, but also for the immune system itself to calm down.

Sleep doesn’t serve one single purpose. It is a complex function and directly related to our health. The multiple functions benefit both our brains and our bodies. Every single brain process and every organ in the body is enhanced by sleep or damaged by the lack of sleep. Within the brain, sleep affects our ability to learn, memorize, and make decisions. It works as an emotional reset so that social and psychological challenges are met with level-headed logic. Sleep provides the opportunity to dream in a world where painful memories are dealt with and future creativity is inspired. While in a sleep state, the body’s immune system is at work to fight cancer, prevent infection, and ward off disease. Sleep balances insulin and circulating glucose to create a metabolic balance. Appetite, weight control, and gut health are all directly tied to adequate sleep levels.

Alcohol destroys our health by attacking our liver and immune system and is related to more than sixty diseases.53 Yet because we are only peripherally aware of the harms but very familiar with pro-alcohol social messages, we often justify our drinking by saying we drink for the taste. And we believe this is true. We have an uncanny ability to unknowingly deceive ourselves.

The Whole30 is ideal to help normalize an overactive immune system, decreasing systemic inflammation and reducing or eliminating the symptoms of your autoimmune disease, chronic pain, or immune-related conditions (like Lyme disease). However, there are some Whole30 Approved foods that are healthy for most people, but might exacerbate your symptoms or fire up your immune system. The trouble is there isn’t just one list of foods that negatively impact all chronic diseases. You are a unique snowflake. That means foods that may be perfectly fine for someone else with your same condition may make your symptoms much worse, and vice-versa. This makes it incredibly hard to create one protocol that works well for everyone with an immune dysfunction. Eggs, tomatoes, peppers, eggplant, potatoes, instant coffee, nuts and seeds, beef, lamb, oranges, grapefruit, lemons, and limes . . . These are all foods that are either known to be commonly problematic for those with autoimmune conditions, or are common food sensitivities for those with increased gut permeability.

For Europe, as for other civilized lands, infections by familiar epidemic disease surely became more frequent, at least in the major ports and at other foci of communication; but infections that returned at more and more frequent intervals became, by necessity, childhood diseases. Older persons would have acquired suitably high and repeatedly reinforced levels of immunity through prior exposures. Thus by a paradox that is only apparent, the more diseased a community, the less destructive its epidemics become. Even very high rates of infant mortality were relatively easily borne. The costs of giving birth and rearing another child to replace one that had died were slight compared to the losses involved in massive adult mortality of the sort that epidemics attacking a population at infrequent intervals inevitably produce. Consequently, the tighter the communications net binding each part of Europe to the rest of the world, the smaller became the likelihood of really devastating disease encounter. Only genetic mutation of a disease-causing organism, or a new transfer of parasites from some other host to human beings offered the possibility of devastating epidemic when world transport and communications had attained a sufficient intimacy to assure frequent circulation of all established human diseases among the civilized populations of the world. Between 1500 and about 1700 this is what seems in fact to have occurred. Devastating epidemics of the sort that had raged so dramatically in Europe's cities between 1346 and the mid-seventeenth century tapered off toward the status of childhood diseases, or else, as in the case of both plague and malaria, notably reduced the geographic range of their incidence. The result of such systematic lightening of the microparasitic drain upon European populations (especially in northwestern Europe where both plague and malaria had about disappeared by the close of the seventeenth century) was, of course, to unleash the possibility of systematic growth. This was, however, only a possibility, since any substantial local growth quickly brought on new problems: in particular, problems of food supply, water supply, and intensification of other infections in cities that had outgrown older systems of waste disposal. After 1600 these factors began to affect European populations significantly, and their effective solution did not come before the eighteenth century - or later. All the same, the changing pattern of epidemic infection was and remains a fundamental landmark in human ecology that deserves more attention than it has ordinarily received. On the time scale of world history, indeed we should view the 'domestication' of epidemic disease that occurred between 1300 and 1700 as a fundamental breakthrough, directly resulting from the two great transportation revolutions of that age - one by land, initiated by the Mongols, and one by sea, initiated by Europeans.

Are you fit enough, are you progressing in your hobby, are you competent as a cook or gardener? And family life—is your marriage intimate enough, your sexual life optimal, have you done all that you can do to raise excellent children? The infant/body rebels under all this pressure, signaling its distress. In response, we find ways to toughen it or to medicate it into silence. So the chronic stress-related symptoms arise, like digestion problems, muscle tension, constant fatigue, insomnia, migraine headaches; or a weak immune system makes us more susceptible to the flu and to colds.

Key to Ratings: Probably OK = (X) Not ideal = (XX) Pretty bad = (XXX) Definitely dangerous = (XXXX) ~ ~ ~ How bad is it to drink water out of a bottle that you left in the car for weeks? (X) First, know that despite scary e-mail forwards from nervous relatives, you needn’t worry about disposable plastic water bottles leaching cancer-causing chemicals into the liquid, according to the American Cancer Society. Commercial water bottles often don’t contain concerning hormone-disrupting chemicals like bisphenol A ( BPA) or phthalates either. But any used bottle can harbor germs from saliva backwash, says Charles Gerba, a microbiologist at the University of Arizona and coauthor of The Germ Freak’s Guide to Outwitting Colds and Flu. Surprisingly, “that’s not really a problem as long as you don’t share the bottle with other people,” he says, since your immune system has already dealt with whatever cold, flu, or other germs may be in your mouth. One exception: sports bottles that you’ve used your thumb or fingers to press shut. Bacteria such as E. coli or Staphylococcus on your hands can contaminate the nozzle when you press it down and then flourish in the

Coincidence? Probably not. Pregnancy isn’t the only time folate is important, of course. A lack of folate is also directly linked to anemia, because folate helps to produce red blood cells.   THE SKIN, AS you’ve probably heard, is the largest organ of the human body. It’s an organ in every sense of the word, responsible for important functions related to the immune system, the nervous system, the circulatory system, and metabolism. The skin protects the body’s stores of folate, and it’s in the skin that a crucial step in the manufacturing of vitamin D takes place.

Most people today live in relatively constant distress and anxiety. This is related to a low-grade but perpetual fight-or-flight response masterminded by the Judge in reaction to the challenges of life, both personal and professional. Though the fight-or-flight response originally evolved to get us out of acute, short-term danger, most of us run the Survivor Brain continuously. The consequence of this perpetual stress and anxiety is heightened blood pressure, increased cardiovascular disease, reduced immune system function, reduced longevity, and reduced happiness and performance.

A cascade of stress-related hormones floods the body in response to the sustained exertion. Blood tests after ultras have shown elevated cardiac enzymes, renal injury, and very high levels of the stress hormone cortisol, the proinflammatory compound interleukin-6, and creatine kinase, a toxic byproduct of muscle breakdown. That’s a lot for the immune system to handle. Approximately one in four runners at the Western States gets a cold after the race, and this is in the height of summer! Most