Human Molecule Quotes

All right," said Susan. "I'm not stupid. You're saying humans need... fantasies to make life bearable." REALLY? AS IF IT WAS SOME KIND OF PINK PILL? NO. HUMANS NEED FANTASY TO BE HUMAN. TO BE THE PLACE WHERE THE FALLING ANGEL MEETS THE RISING APE. "Tooth fairies? Hogfathers? Little—" YES. AS PRACTICE. YOU HAVE TO START OUT LEARNING TO BELIEVE THE LITTLE LIES. "So we can believe the big ones?" YES. JUSTICE. MERCY. DUTY. THAT SORT OF THING. "They're not the same at all!" YOU THINK SO? THEN TAKE THE UNIVERSE AND GRIND IT DOWN TO THE FINEST POWDER AND SIEVE IT THROUGH THE FINEST SIEVE AND THEN SHOW ME ONE ATOM OF JUSTICE, ONE MOLECULE OF MERCY. AND YET—Death waved a hand. AND YET YOU ACT AS IF THERE IS SOME IDEAL ORDER IN THE WORLD, AS IF THERE IS SOME...SOME RIGHTNESS IN THE UNIVERSE BY WHICH IT MAY BE JUDGED. "Yes, but people have got to believe that, or what's the point—" MY POINT EXACTLY.

Beyond a critical point within a finite space, freedom diminishes as numbers increase. This is as true of humans as it is of gas molecules in a sealed flask. The human question is not how many can possibly survive within the system, but what kind of existence is possible for those who so survive.

On Titan the molecules that have been raining down like manna from heaven for the last 4 billion years might still be there largely unaltered deep-frozen awaiting the chemists from Earth

I arise in the morning torn between a desire to improve the world and a desire to enjoy the world. This makes it hard to plan the day.

From dopamine’s point of view, having things is uninteresting. It’s only getting things that matters. If you live under a bridge, dopamine makes you want a tent. If you live in a tent, dopamine makes you want a house. If you live in the most expensive mansion in the world, dopamine makes you want a castle on the moon. Dopamine has no standard for good, and seeks no finish line. The dopamine circuits in the brain can be stimulated only by the possibility of whatever is shiny and new, never mind how perfect things are at the moment. The dopamine motto is “More.

Personally, I believe that prayer is a sending out of vibrations from one person to another and to God. All of the universe is in vibration. There are vibrations in the molecules of a table. The air is filled with vibrations. The reaction between human beings is also in vibration. When you send out a prayer for another person, you employ the force inherent in a spiritual universe. You transport from yourself to the other person a sense of love, helpfulness, support—a sympathetic, powerful understanding—and in this process you awaken vibrations in the universe through which

The day was ill-omened from the beginning; one of those unlucky days when every little detail seems to go wrong and one finds oneself engaged in a perpetual and infuriating strife with inanimate objects. How truly fiendish the sub-human world can be on these occasions! How every atom, every cell, every molecule, seems to be leagued in a maddening conspiracy against the unfortunate being who has incurred its obscure displeasure!

High levels of dopamine suppress H&N functioning, so brilliant people are often poor at human relationships. We need H&N empathy to understand what’s going on in other people’s minds, an essential skill for social interaction.

overweight children are more likely to be hit by cars when they’re crossing the street. It’s not because they walk more slowly; it’s because they’re impulsive.

She couldn't get any further at that point. The sky full of stars seemed dead and cold, everything in it the result of the mechanical, indifferent interactions of molecules and particles that would continue for the rest of time whether Lyra lived or died, whether human beings were conscious or unconscious: a vast silent empty indifference, all quite meaningless. Reason had brought her to this state. She had exalted reason over every other faculty. The result had been - was now - the deepest unhappiness she had ever felt.

Winners cheat for the same reason that drug addicts take drugs. The rush feels great, and withdrawal feels terrible. Both know that their behavior has the potential to destroy their lives, but the desire circuit doesn’t care. It only wants more.

I am a collection of water, calcium and organic molecules called Carl Sagan. You are a collection of almost identical molecules with a different collective label. But is that all? Is there nothing in here but molecules? Some people find this idea somehow demeaning to human dignity. For myself, I find it elevating that our universe permits the evolution of molecular machines as intricate and subtle as we. But the essence of life is not so much the atoms and simple molecules that make us up as the way in which they are put together. Every now and then we read that the chemicals which constitute the human body cost ninety-seven cents or ten dollars or some such figure; it is a little depressing to find our bodies valued so little. However, these estimates are for human beings reduced to our simplest possible components. We are made mostly of water, which costs almost nothing; the carbon is costed in the form of coal; the calcium in our bones as chalk; the nitrogen in our proteins as air (cheap also); the iron in our blood as rusty nails. If we did not know better, we might be tempted to take all the atoms that make us up, mix them together in a big container and stir. We can do this as much as we want. But in the end all we have is a tedious mixture of atoms. How could we have expected anything else?

Much like a food, a psychoactive drug is not a thing — without a human brain, it is inert — so much as it is a relationship; it takes both a molecule and a mind to make anything happen.

Human beings used to be molecules which could do many, many different sorts of dances, or decline to dance at all --as they pleased. My mother could do the waltz, the tango, the rumba....

The history of human use of plants, mushrooms, and animals for their psychedelic effects is far older than written history, and probably predates the appearance of the modern human species.

It’s not enough to just imagine the future. To bring an idea to fruition we must struggle with the uncompromising realities of the physical world. We need not only knowledge but also tenacity.

Nature loves efficiency, which is very odd for something supposedly working at random. When you drop a ball, it falls straight down without taking any unexpected detours. When two molecules with the potential for bonding meet, they always bond- there is no room for indecision. This expenditure of least energy, also called the law of least effort, covers human beings, too. Certainly our bodies cannot escape the efficiency of the chemical processes goings on in each cell, so it is probable that our whole being is wrapped up in the same principle. This argument also applies to personal growth- the idea that everyone is doing the best he or she can from his or her own level of consciousness

The smallest component of the human molecule is a vibration - the equivalent to a musical note. Taking the time to learn more self-awareness at this level creates life experiences beyond that of all the greatest symphonies ever heard

The desire circuit often breaks its promises—which is bound to happen, because it plays no role in generating feelings of satisfaction. It is in no position to make dreams come true. The desire circuit is, so to speak, just a salesman.

Mushrooms have taught me the interconnectedness of all life-forms and the molecular matrix that we share,” he explains in another one. “I no longer feel that I am in this envelope of a human life called Paul Stamets. I am part of the stream of molecules that are flowing through nature. I am given a voice, given consciousness for a time, but I feel that I am part of this continuum of stardust into which I am born and to which I will return at the end of this life.

Giving in to craving doesn’t necessarily lead to pleasure because wanting is different from liking. Dopamine makes promises that it is in no position to keep. “If you buy these shoes, your life will change,” says the desire circuit, and it just might happen, but not because dopamine made you feel it.

Two chemicals called actin and myosin evolved eons ago to allow the muscles in insect wings to contract and relax. Thus, insects learned to fly. When one of those paired molecules are absent, wings will grow but they cannot flap and are therefore useless. Today, the same two proteins are responsible for the beating of the human heart, and when one is absent, the person’s heartbeat is inefficient and weak, ultimately leading to heart failure. Again, science marvels at the way molecules adapt over millions of years, but isn’t there a deeper intent? In our hearts, we feel the impulse to fly, to break free of boundaries. Isn’t that the same impulse nature expressed when insects began to take flight? The prolactin that generates milk in a mother’s breast is unchanged from the prolactin that sends salmon upstream to breed, enabling them to cross from saltwater to fresh.

Talking has saved me, again and again. It is okay—and you absolutely deserve—to ask for help when things are hard. Remember, lovely human, that you matter very much. You are a miracle of molecules: infinite and extraordinary.

One cool judgment is worth a dozen hasty councils.

We all behave like Maxwell’s demon. Organisms organize. In everyday experience lies the reason sober physicists across two centuries kept this cartoon fantasy alive. We sort the mail, build sand castles, solve jigsaw puzzles, separate wheat from chaff, rearrange chess pieces, collect stamps, alphabetize books, create symmetry, compose sonnets and sonatas, and put our rooms in order, and all this we do requires no great energy, as long as we can apply intelligence. We propagate structure (not just we humans but we who are alive). We disturb the tendency toward equilibrium. It would be absurd to attempt a thermodynamic accounting for such processes, but it is not absurd to say we are reducing entropy, piece by piece. Bit by bit. The original demon, discerning one molecules at a time, distinguishing fast from slow, and operating his little gateway, is sometimes described as “superintelligent,” but compared to a real organism it is an idiot savant. Not only do living things lessen the disorder in their environments; they are in themselves, their skeletons and their flesh, vesicles and membranes, shells and carapaces, leaves and blossoms, circulatory systems and metabolic pathways - miracles of pattern and structure. It sometimes seems as if curbing entropy is our quixotic purpose in the universe.

Dopamine isn’t the pleasure molecule, after all. It’s the anticipation molecule. To enjoy the things we have, as opposed to the things that are only possible, our brains must transition from future-oriented dopamine to present-oriented chemicals, a collection of neurotransmitters we call the Here and Now molecules, or the H&Ns. Most people have heard of the H&Ns. They include serotonin, oxytocin, endorphins (your brain’s version of morphine), and a class of chemicals called endocannabinoids (your brain’s version of marijuana). As opposed to the pleasure of anticipation via dopamine, these chemicals give us pleasure from sensation and emotion. In fact, one of the endocannabinoid molecules is called anandamide, named after a Sanskrit word that means joy, bliss, and delight.

Man is no form no mighty molecule no just idea alone — all that Thing — I feel man tender radiance at Heart between breast and belly, that physical place where the Self urges — delicate sensation

No man is an island, said John Donne, but I humbly dare to add: No man or woman is an island, but every one of us is a peninsula, half attached to the mainland, half facing the ocean – one half connected to family and friends and culture and tradition and country and nation and sex and language and many other things, and the other half wanting to be left alone to face the ocean. I think we ought to be allowed to remain peninsulas. Every social and political system that turns each of us into a Donnean island and the rest of humankind into an enemy or a rival is a monster. But at the same time every social and political and ideological system that wants to turn each of us into no more than a molecule of the mainland is also a monstrosity. The condition of peninsula is the proper human condition. That's what we are and that's what we deserve to remain.

If there is as a continuum from self-reproducing molecules, such as DNA, to microbes, and an evolutionary sequence continuum from microbes to humans, why should we imagine that continuum to stop at humans?

Humans are organisms, subject to physical laws, including alas, the one that says entropy always increases. Diseases are molecules misbehaving; the basic requirement of life is metabolism, and death its cessation.

How Smart Is a Rock? To appreciate the feasibility of computing with no energy and no heat, consider the computation that takes place in an ordinary rock. Although it may appear that nothing much is going on inside a rock, the approximately 1025 (ten trillion trillion) atoms in a kilogram of matter are actually extremely active. Despite the apparent solidity of the object, the atoms are all in motion, sharing electrons back and forth, changing particle spins, and generating rapidly moving electromagnetic fields. All of this activity represents computation, even if not very meaningfully organized. We’ve already shown that atoms can store information at a density of greater than one bit per atom, such as in computing systems built from nuclear magnetic-resonance devices. University of Oklahoma researchers stored 1,024 bits in the magnetic interactions of the protons of a single molecule containing nineteen hydrogen atoms.51 Thus, the state of the rock at any one moment represents at least 1027 bits of memory.

Imagine trying to live in a world dominated by dihydrogen oxide, a compound that has no taste or smell and is so variable in its properties that it is generally benign but at other times swiftly lethal. Depending on its state, it can scald you or freeze you. In the presence of certain organic molecules it can form carbonic acids so nasty that they can strip the leaves from trees and eat the faces off statuary. In bulk, when agitated, it can strike with a fury that no human edifice could withstand. Even for those who have learned to live with it, it is an often murderous substance. We call it water.

Every cell and molecule of who I am desires, needs and covets Layla. Humans call that love. I call it obsession. Same thing, I suppose, but I am a demon, Trinity. I'm brutally selfish and there are very few things I truly care about. While I may randomly commit acts of perceived kindness, I do them only so that Layla is happy. Because when she's not happy, it makes me want to do really, really bad things to whatever and whoever has upset her.

All right,” said Susan. “I’m not stupid. You’re saying humans need…fantasies to make life bearable.” REALLY? AS IF IT WAS SOME KIND OF PINK PILL? NO. HUMANS NEED FANTASY TO BE HUMAN. TO BE THE PLACE WHERE THE FALLING ANGEL MEETS THE RISING APE. “Tooth fairies? Hogfathers? Little—” YES. AS PRACTICE. YOU HAVE TO START OUT LEARNING TO BELIEVE THE LITTLE LIES. “So we can believe the big ones?” YES. JUSTICE. MERCY. DUTY. THAT SORT OF THING. “They’re not the same at all!” YOU THINK SO? THEN TAKE THE UNIVERSE AND GRIND IT DOWN TO THE FINEST POWDER AND SIEVE IT THROUGH THE FINEST SIEVE AND THEN SHOW ME ONE ATOM OF JUSTICE, ONE MOLECULE OF MERCY. AND YET—Death waved a hand. AND YET YOU ACT AS IF THERE IS SOME IDEAL ORDER IN THE WORLD, AS IF THERE IS SOME…SOME RIGHTNESS IN THE UNIVERSE BY WHICH IT MAY BE JUDGED. “Yes, but people have got to believe that, or what’s the point—” MY POINT EXACTLY. She tried to assemble her thoughts. THERE IS A PLACE WHERE TWO GALAXIES HAVE BEEN COLLIDING FOR A MILLION YEARS, said Death, apropos of nothing. DON’T TRY TO TELL ME THAT’S RIGHT. “Yes, but people don’t think about that,” said Susan. “Somewhere there was a bed…” CORRECT. STARS EXPLODE, WORLDS COLLIDE, THERE’S HARDLY ANYWHERE IN THE UNIVERSE WHERE HUMANS CAN LIVE WITHOUT BEING FROZEN OR FRIED, AND YET YOU BELIEVE THAT A…A BED IS A NORMAL THING. IT IS THE MOST AMAZING TALENT. “Talent?” OH, YES. A VERY SPECIAL KIND OF STUPIDITY. YOU THINK THE WHOLE UNIVERSE IS INSIDE YOUR HEADS. “You make us sound mad,” said Susan. A nice warm bed… NO. YOU NEED TO BELIEVE IN THINGS THAT AREN’T TRUE. HOW ELSE CAN THEY BECOME? said Death

Albert Einstein once said, "My passionate sense of social justice and social responsibility has always contrasted oddly with my pronounced lack of need for direct contact with other human beings and human communities". And "I love Humanity but I hate humans." The abstract concepts of social justice and humanity came easily, but the concrete experience of encountering another person was too hard.

There are few things we encounter in daily life that are more unlikely than winning the lottery. A person is more likely to have identical quadruplets, or be killed by a vending machine tipping over. It’s over a hundred times more likely that a person will be struck by lightning than win the lottery. Yet millions of people buy tickets.

The feelings of excitement, enthusiasm, and energy dissipate. Dopamine has shut down. Dopamine circuits don’t process experience in the real world, only imaginary future possibilities. For many people it’s a letdown. They’re so attached to dopaminergic stimulation that they flee the present and take refuge in the comfortable world of their own imagination. “What will we do tomorrow?” they ask themselves as they chew their food, oblivious to the fact that they’re not even noticing this meal they had so eagerly anticipated. To travel hopefully is better than to arrive is the motto of the dopamine enthusiast.

Consider all the inanimate matter in the universe, all the dumb atoms, all the mindless molecules, all the oblivious dust grains and pebbles and rocks and iceballs and worlds and stars, all the unthinking galaxies and superclusters, wheeling through the oblivious time-haunted megaparsecs of the cosmic supervoid. In all that immensity, she had somehow contrived to BE a human being, a microscopically tiny, cosmically insignificant bundle of information-processing systems, wired to a mind more structurally complex than the Milky Way itself, maybe even more complex than the rest of the *whole damned universe*!

Organism is opposed to chaos, to disintegration, to death, as message is to noise. To describe an organism, we do not try to specify each molecule in it, and catalogue it bit by bit, but rather to answer certain questions about it which reveal its pattern: a pattern which is more significant and less probable as the organism becomes, so to speak, more fully an organism.

ideas are so elastic in a human brain, that they have no constant measure which may be called their actual bulk. Any important idea may be compressed to a molecule by an unwonted crowding of others; and any small idea will expand to whatever length and breadth of vacuum the mind may be able to make over to it.

Nicotine, in fact, is an unusual drug because it does very little except trigger compulsive use. According to researcher Roland R. Griffiths, PhD, professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine, “When you give people nicotine for the first time, most people don’t like it. It’s different from many other addictive drugs, for which most people say they enjoy the first experience and would try it again.” Nicotine doesn’t make you high like marijuana or intoxicated like alcohol or wired up like speed. Some people say it makes them feel more relaxed or more alert, but really, the main thing it does is relieve cravings for itself. It’s the perfect circle. The only point of smoking cigarettes is to get addicted so one can experience the pleasure of relieving the unpleasant feeling of craving, like a man who carries around a rock all day because it feels so good when he puts it down.

In the Game of Life, as in our world, self-reproducing patterns are complex objects. One estimate, based on the earlier work of mathematician John von Neumann, places the minimum size of a self-replicating pattern in the Game of Life at ten trillion squares—roughly the number of molecules in a single human cell.

Now there grows among all the rooms, replacing the night's old smoke, alcohol and sweat, the fragile, musaceous odor of Breakfast: flowery, permeating, surprising, more than the colour of winter sunlight, taking over not so much through any brute pungency or volume as by the high intricacy to the weaving of its molecules, sharing the conjuror's secret by which - though it is not often Death is told so clearly to fuck off - the living genetic chains prove even labyrinthine enough to preserve some human face down ten or twenty generations... so the same assertion-through-structure allows this war morning's banana fragrance to meander, repossess, prevail. Is there any reason not to open every window, and let the kind scent blanket all Chelsea? As a spell, against falling objects...

I am a collection of water, calcium and organic molecules called Carl Sagan. You are a collection of almost identical molecules with a different collective label. But is that all? Is there nothing in here but molecules? Some people find this idea somehow demeaning to human dignity. For myself, I find it elevating that our universe permits the evolution of molecular machines as intricate and subtle as we.

Before we came to believe humans were so important before this awful loneliness. Can molecules recall it? what once was? Before anything happen? No I, No we, No one. No way. No verb. No noun. only a tiny dot brimming with is is is is is is All everything home.

Some say we are not like humans but we are more like them than we are different. Man and animals are in the same species as mammals as they have mammary glands that produce the milk to nurse their young. Their lungs breathe air and their blood is warm. They are vertebrates in that their skeletal system and well-designed spines hold their bodies together. Each cell is made of molecules, each molecule is made of atoms, and each atom is made of protons, neutrons and mostly electrons, which are made of waves of fibered light.

Factoid: Within the class of nutrients called ‘carbohydrates’, there is no molecule that is essential for human health or well-being. This does not mean that blood sugar is completely unimportant, but rather that blood sugar can be well-maintained via metabolic processes such as gluconeogenesis without dietary carbohydrates in the keto-adapted human.

Everything is energy. All energy has a frequency, a vibration. White light is made up of the rainbow of colors, red with the lowest frequency and violet with the highest. Humans are made of matter, which is made of energy. If we take the most powerful microscopes and zoom in on any cell in the body, we go past the cells, DNA, base molecules, atoms, and electrons all the way down to quanta of energy and a lot of space. What is mind-blowing at this quantum level is that the act of observing these subatomic particles changes how they behave! It is as though they are aware of us and make decisions.

All of us, while apparently separate and distinct individuals, are but the molecules of which the body of humanity is composed, and each of us feels a compulsion to function as a part of the whole. Consciously or subconsciously we long to be useful and accepted, regarded with favor. Loss of sight does not change this, I discovered; I needed to find a way to belong.

Human remains dogs are distinct from the dogs that search for escaped felons and the dogs that search for whole cadavers. They are trained to alert their owners when they detect the specific scents of decomposed human tissue. They can pinpoint the location of a corpse at the bottom of a lake by sniffing the water’s surface for the gases and fats that float up from the rotting remains. They can detect the lingering scent molecules of a decomposing body up to fourteen months after the killer lugged it away.

This temporary world is of death. Here, everything dies and everything changes. Do you recognise that subtle field of energy, that subatomic level of energy which does not change? Objects disintegrate, but atoms remain the same. Atoms and molecules disintegrate, but the sub-atomic particles are the same. All these human bodies are different, but there is one field of energy, the mind, that flows through everybody. Do you realize that there is one thing that is in everybody? Do you recognize the one consciousness?

Like no other particle on earth, the morphine molecule seemed to possess heaven and hell. It allowed for modern surgery, saving and improving too many lives to count. It stunted and ended too many lives to count with addiction and overdose. Discussing it, you could invoke some of humankind’s greatest cultural creations and deepest questions: Faust, Dr. Jekyll and Mr. Hyde, discussions on the fundamental nature of man and human behavior, of free will and slavery, of God and evolution. Studying the molecule you naturally wandered into questions like, Can mankind achieve happiness without pain? Would that happiness even be worth it? Can we have it all?

The drug war’s simplistic account of what drugs do and are, as well as its insistence on lumping them all together under a single meaningless rubric, has for too long prevented us from thinking clearly about the meaning and potential of these very different substances. The legal status of this or that molecule is one of the least interesting things about it. Much like a food, a psychoactive drug is not a thing—without a human brain, it is inert—so much as it is a relationship; it takes both a molecule and a mind to make anything happen.

When it all comes crashing down Try to understand your meanings No one said it would be easy This living, it ain't easy, oh You were sewn together with a tapestry of molecules A billion baby galaxies and wide open spaces And everything you need is here Everything you fear is here And it's holding you up It just keeps holding you up When you came up from the ground From a million little pieces You're a pretty human being

Stress and glucocorticoids have inverted-U effects here as well. Moderate, transient stress (or exposure to the equivalent glucocorticoid levels) increases spine number in the hippocampus; sustained stress or glucocor-ticoid exposure does the opposite.7 Moreover, major depression or anxiety—two disorders associated with elevated glucocorticoid levels—can reduce hippocampal dendrite and spine number. This arises from decreased levels of that key growth factor mentioned earlier this chapter, BDNF. Sustained stress and glucocorticoids also cause dendritic retraction and synapse loss, lower levels of NCAM (a “neural cell adhesion molecule” that stabilizes synapses), and less glutamate release in the frontal cortex.

People ask, How did you get in there? What they really want to know is if they are likely to end up in there as well. I can’t answer the real question. All I can tell them is, It’s easy. And it is easy to slip into a parallel universe. There are so many of them: worlds of the insane, the criminal, the crippled, the dying, perhaps of the dead as well. These worlds exist alongside this world and resemble it, but are not in it.… …In the parallel universe the laws of physics are suspended. What goes up does not necessarily come down, a body at rest does not tend to stay at rest; and not every action can be counted on to provoke an equal and opposite reaction. Time, too, is different. It may run in circles, flow backward, skip about from now to then. The very arrangement of molecules is fluid: Tables can be clocks; faces, flowers. These are facts you find out later, though. Another odd feature of the parallel universe is that although it is invisible from this side, once you are in it you can easily see the world you came from. Sometimes the world you came from looks huge and menacing, quivering like a vast pile of jelly; at other times it is miniaturized and alluring, a-spin and shining in its orbit. Either way, it can’t be discounted. Every window on Alcatraz has a view of San Francisco.

Every day, hundreds of observations and experiments pour into the hopper of the scientific literature. Many of them don't have much to do with evolution - they're observations about the details of physiology, biochemistry, development, and so on - but many of them do. And every fact that has something to do with evolution confirms its truth. Every fossil that we find, every DNA molecule that we sequence, every organ system that we dissect, supports the idea that species evolved from common ancestors. Despite innumerable possible observations that could prove evolution untrue, we don't have a single one. We don't find mammals in Precambrian rocks, humans in the same layers as dinosaurs, or any other fossils out of evolutionary order. DNA sequencing supports the evolutionary relationships of species originally deduced from the fossil record. And, as natural selection predicts, we find no species with adaptations that only benefit a different species. We do find dead genes and vestigial organs, incomprehensible under the idea of special creation. Despite a million chances to be wrong, evolution always comes up right. That is as close as we can get to a scientific truth.

Newton was haunted by insanity. He spent hours trying to find hidden messages in the Bible, and wrote over a million words on religion and the occult. He pursued the medieval art of alchemy, obsessively searching for the philosopher’s stone, a mythical substance that alchemists believed had magical properties and could even help humans achieve immortality. At the age of fifty, Newton became fully psychotic and spent a year in an insane asylum.

If a tree falls in a forest and no one is there to hear it, does it make a sound? (The question was first posed by the Irish philosopher George Berkeley.) Simply, no—sound is a mental image created by the brain in response to vibrating molecules. Similarly, there can be no pitch without a human or animal present. A suitable measuring device can register the frequency made by the tree falling, but truly it is not pitch unless and until it is heard.

The bombs disrupted molecular structures. The cocktails included the distribution of nanotechnology to help to speed up the recovery of the earth - nanotechnology that promotes the self-assembly of molecules. The nanotechnology, speed up by DNA, which is an informational material but also excellent at the self-assembly of cells, made our fusing stronger. And the nanotechnology that hit the humans trapped in rubble or scorched land helped them to regenerate.

We’ve all seen “quit smoking” advertisements on buses and subways. They don’t work. We’ve heard about school programs that teach kids to say no to drugs and alcohol. In many cases drug and alcohol use go up after these programs because they pique the curiosity of the adolescent students. The only thing that has been shown to work consistently is raising taxes on these products and placing limits on where and when they can be sold. When these measures are taken, use goes down.

The convert will understand. How do they translate ºyw in your English interpretation?” “Atom,” said the convert. “You don’t find that strange, considering atoms were unknown in the sixth century?” The convert chewed her lip. “I never thought of that,” she said. “You’re right. There’s no way atom is the original meaning of that word.” “Ah.” Vikram held up two fingers in a sign of benediction. He looked, Alif thought, like some demonic caricature of a saint. “But it is. In the twentieth century, atom became the original meaning of ºyw, because an atom was the tiniest object known to man. Then man split the atom. Today, the original meaning might be hadron. But why stop there? Tomorrow, it might be quark. In a hundred years, some vanishingly small object so foreign to the human mind that only Adam remembers its name. Each of those will be the original meaning of ºyw.” Alif snorted. “That’s impossible. ºyw must refer to some fundamental thing. It’s attached to an object.” “Yes it is. The smallest indivisible particle. That is the meaning packaged in the word. No part of it lifts out—it does not mean smallest, nor indivisible, nor particle, but all those things at once. Thus, in man’s infancy, ºyw was a grain of sand. Then a mote of dust. Then a cell. Then a molecule. Then an atom. And so on. Man’s knowledge of the universe may grow, but ºyw does not change.” “That’s . . .” The convert trailed off, looking lost. “Miraculous. Indeed.

The morphine molecule exerts an analogous brainwashing on humans, pushing them to act contrary to their self-interest in pursuit of the molecule. Addicts betray loved ones, steal, live under freeways in harsh weather, and run similarly horrific risks to use the molecule. It became the poster molecule for an age of excess. No amount of it was ever enough. The molecule created ever-higher tolerance. Plus, it had a way of railing on when the body gathered the courage to throw it out. This wasn’t only during withdrawals. Most drugs are easily reduced to water-soluble glucose in the human body, which then expels them. Alone in nature, the morphine molecule rebelled. It resisted being turned into glucose and it stayed in the body. “We still can’t explain why this happens. It just doesn’t follow the rules. Every other drug in the world—thousands of them—follows this rule. Morphine doesn’t,” Coop said. “It really is almost like someone designed it that way—diabolically so.

Identifying ourselves with our dopamine circuits traps us in a world of speculation and possibility. The concrete world of here and now is disdained, ignored, or even feared, because we can’t control it. We can only control the future, and giving up control is not something dopaminergic creatures like to do. But none of it is real. Even a future one second away is unreal. It is only the stark facts of the present that are real, facts that must be accepted exactly as they are, facts that cannot be modified by a hair’s breadth to suit our needs. This is the world of reality. The future, where dopaminergic creatures live their lives, is a world of phantoms.

The fundamental error of socialism is anthropological in nature. Socialism considers the individual person simply as an element, a molecule within the social organism, so that the good of the individual is completely subordinated to the functioning of the socio-economic mechanism. Socialism likewise maintains that the good of the individual can be realized without reference to his free choice, to the unique and exclusive responsibility which he exercises in the face of good or evil. Man is thus reduced to a series of social relationships, and the concept of the person as the autonomous subject of moral decision disappears, the very subject whose decisions build the social order. From this mistaken conception of the person there arise both a distortion of law, which defines the sphere of the exercise of freedom, and an opposition to private property. A person who is deprived of something he can call “his own,” and of the possibility of earning a living through his own initiative, comes to depend on the social machine and on those who control it. This makes it much more difficult for him to recognize his dignity as a person, and hinders progress towards the building up of an authentic human community.

There is a massive, irreconcilable conflict between science and religion. Religion was humanity's original cosmology, biology and anthropology. It provided explanations for the origin of the world, life and humans. Science now gives us increasingly complete explanations for those big three. We know the origins of the universe, the physics of the big bang and how the basic chemical elements formed in supernovas. We know that life on this planet originated about 4 billion years ago, and we are all descendants of that original replicating molecule. Thanks to Darwin we know that natural selection is the only workable explanation for the design and variety of all life on this planet. Paleoanthropologists and geneticists have reconstructed much of the human tree of life. We are risen apes, not fallen angels. We are the most successful and last surviving African hominid. Every single person on this Earth, all 7 billion of us, arose 50,000 years ago from small bands of African hunter-gatherers, a total population of somewhere between 600 and 2,000 individuals.

From dopamine’s point of view, having things is uninteresting. It’s only getting things that matters. If you live under a bridge, dopamine makes you want a tent. If you live in a tent, dopamine makes you want a house. If you live in the most expensive mansion in the world, dopamine makes you want a castle on the moon. Dopamine has no standard for good, and seeks no finish line. The dopamine circuits in the brain can be stimulated only by the possibility of whatever is shiny and new, never mind how perfect things are at the moment.

Yet, at the quantum level, NO part of the body lives apart from the rest. There are no wires holding together the molecules of your arteries, just as there are no visible connections binding together the stars in a galaxy. Yet arteries and galaxies are both securely held together, in a seamless, perfect design. The invisible bonds that you cannot examine under a microscope are quantum in nature; without this "hidden physiology," your visible physiology could not exist. It would never have been more than a random collection of molecules.

Only the neurosurgeon dares to improve upon five billion years of evolution in a few hours. The human brain. A trillion nerve cells storing electrical patterns more numerous than the water molecules of the world’s oceans. The soul’s tapestry lies woven in the brain’s nerve threads. Delicate, inviolate, the brain floats serenely in a bone vault like the crown jewel of biology. What motivated the vast leap in intellectual horsepower between chimp and man? Between tree dweller and moon walker? Is the brain a gift from God, or simply the jackpot of a trillion rolls of DNA dice?

People who live with ADHD are at high risk of addiction, especially adolescents, because of their poorly functioning frontal lobes. Years ago, when the illness was less well understood, doctors and parents were reluctant to give these vulnerable children addictive drugs such as Ritalin and amphetamine. It sounded reasonable: don’t give addictive substances to people at risk for addiction. But rigorous testing showed unambiguously that adolescents who were treated with stimulant drugs were less likely to develop addictions. In fact, those who started the drug at the youngest age and took the highest doses were the least likely to develop problems with illicit drugs. Here’s why: if you strengthen the dopamine control circuit, it’s a lot easier to make wise decisions. On the other hand, if effective treatment is withheld, the weakness of the control circuit is not corrected. The desire circuit acts unopposed, increasing the likelihood of high-risk, pleasure-seeking behavior.

Instead of taking a bow for walking on the moon, Colonel Buzz Aldrin, PhD, told his admirers, “It’s something we did. Now we should do something else,” apparently no more satisfied than if he had painted a fence. His desire was not to bask in his glory but to find “something else”—the next big challenge that could hold his interest. This perpetual need to identify a goal and calculate a way to reach it was perhaps the most important factor in his historic success. But it’s not easy having so much dopamine coursing through the control circuits. It almost certainly played a significant role in Aldrin’s post-lunar struggle with depression, alcoholism, three divorces, suicidal impulses, and a stay on a psychiatric ward, which he described in his candid autobiography, Magnificent Desolation: The Long Journey Home from the Moon.

Look in it,' he said, smiling slightly, as you do when you have given someone a present which you know will please him and he is unwrapping it before your eyes. I opened it. In the folder I found four 8×10 glossy photos, obviously professionally done; they looked like the kind of stills that the publicity departments of movie studios put out. The photos showed a Greek vase, on it a painting of a male figure who we recognized as Hermes. Twined around the vase the double helix confronted us, done in red glaze against a black background. The DNA molecule. There could be no mistake. 'Twenty-three or -four hundred years ago,' Fat said. 'Not the picture but the krater, the pottery.' 'A pot,' I said. 'I saw it in a museum in Athens. It's authentic. Thats not a matter of my own opinion; I'm not qualified to judge such matters; it's authenticity has been established by the museum authorities. I talked with one of them. He hadn't realized what the design shows; he was very interested when I discussed it with him. This form of vase, the krater, was the shape later used as the baptismal font. That was one of the Greek words that came into my head in March 1974, the word “krater”. I heard it connected with another Greek word: “poros”. The words “poros krater” essentially mean “limestone font”. ' There could be no doubt; the design, predating Christianity, was Crick and Watson's double helix model at which they had arrived after so many wrong guesses, so much trial-and-error work. Here it was, faithfully reproduced. 'Well?' I said. 'The so-called intertwined snakes of the caduceus. Originally the caduceus, which is still the symbol of medicine was the staff of- not Hermes-but-' Fat paused, his eyes bright. 'Of Asklepios. It has a very specific meaning, besides that of wisdom, which the snakes allude to; it shows that the bearer is a sacred person and not to be molested...which is why Hermes the messenger of the gods, carried it.' None of us said anything for a time. Kevin started to utter something sarcastic, something in his dry, witty way, but he did not; he only sat without speaking. Examining the 8×10 glossies, Ginger said, 'How lovely!' 'The greatest physician in all human history,' Fat said to her. 'Asklepios, the founder of Greek medicine. The Roman Emperor Julian-known to us as Julian the Apostate because he renounced Christianity-conside​red Asklepios as God or a god; Julian worshipped him. If that worship had continued, the entire history of the Western world would have basically changed

If I longed for destruction it was merely that this eye might be extinguished. I longed for an earthquake, for some cataclysm of nature which would plunge the lighthouse into the sea. I wanted a metamorphosis, a change to fish, to leviathan, to destroyer. I wanted the earth to open up, to swallow everything in one engulfing yawn. I wanted to see the city buried fathoms deep in the bosom of the sea. I wanted to sit in a cave and read by candlelight. (I wanted that eye extinguished so that I might have a change to know my own body, my own desires. I wanted to be alone for a thousand years in order to reflect on what I had seen and heard - and in order to forget. I wanted something of the earth which was not of man's doing, something absolutely divorced from the human of which I was surfeited. I wanted something purely terrestrial and absolutely divested of idea. I wanted to feel the blood running back into my veins, even at the cost of annihilation. I wanted to shake the stone and the light out of my system. I wanted the dark fecundity of nature, the deep well of the womb, silence, or else the lapping of the black waters of death. I wanted to be that night which the remorseless eye illuminated, a night diapered with stars and trailing comets. To be of night, so frighteningly silent, so utterly incomprehensible and eloquent at the same time. Never more to speak or to listen or to think. To be englobed and encompassed and to encompass and to englobe at the same time. No more pity, no more tenderness. To be human only terrestrially, like a plant or a worm or a brook. To be decomposed, divested of light and stone, variable as the molecule, durable as the atom, heartless as the earth itself.

Throughout the human life span there remains a constant two-way interaction between psychological states and the neurochemistry of the frontal lobes, a fact that many doctors do not pay enough attention to. One result is the overreliance on medications in the treatment of mental disorders. Modern psychiatry is doing too much listening to Prozac and not enough listening to human beings; people’s life histories should be given at least as much importance as the chemistry of their brains. The dominant tendency is to explain mental conditions by deficiencies of the brain’s chemical messengers, the neurotransmitters. As Daniel J. Siegel has sharply remarked, “We hear it said everywhere these days that the experience of human beings comes from their chemicals.” Depression, according to the simple biochemical model, is due to a lack of serotonin — and, it is said, so is excessive aggression. The answer is Prozac, which increases serotonin levels in the brain. Attention deficit is thought to be due in part to an undersupply of dopamine, one of the brain’s most important neurotransmitters, crucial to attention and to experiencing reward states. The answer is Ritalin. Just as Prozac elevates serotonin levels, Ritalin or other psychostimulants are thought to increase the availability of dopamine in the brain’s prefrontal areas. This is believed to increase motivation and attention by improving the functioning of areas in the prefrontal cortex. Although they carry some truth, such biochemical explanations of complex mental states are dangerous oversimplifications — as the neurologist Antonio Damasio cautions: "When it comes to explaining behavior and mind, it is not enough to mention neurochemistry... The problem is that it is not the absence or low amount of serotonin per se that “causes” certain manifestations. Serotonin is part of an exceedingly complicated mechanism which operates at the level of molecules, synapses, local circuits, and systems, and in which sociocultural factors, past and present, also intervene powerfully. The deficiencies and imbalances of brain chemicals are as much effect as cause. They are greatly influenced by emotional experiences. Some experiences deplete the supply of neurotransmitters; other experiences enhance them. In turn, the availability — or lack of availability — of brain chemicals can promote certain behaviors and emotional responses and inhibit others. Once more we see that the relationship between behavior and biology is not a one-way street.

they say that everything in the world is an illusion, that it’s not real. but how’s it an illusion? who’d say those real, material things right there in front of you are fake, right? the form that material things exist in is one way, while the form they manifest in, it turns out, is different. and our eyes have an ability: they can fix the material things in our material dimension so that they appear to be in the state we now see. but actually, that’s not their state. that’s not even their state in our dimension. for example, what does a human being look like under a microscope? his whole body is loose and made up of little molecules, just like grains of sand, and they’re granular and in motion, electrons are orbiting nuclei, the whole body is wriggling and in motion, and the surface of the body isn’t smooth, it’s irregular. the same goes for every material thing in the universe, be it steel, iron, stone, or whatever, all the molecular elements inside them are in motion. you really can’t see the overall form of it, and the truth is, none of those things are static. this table is wriggling too, but your eyes can’t see the reality of it. so this pair of eyes can give you a false image.

The popular antidepressant Prozac, which acts by blocking the reuptake of serotonin and probably increasing its availability, has received wide attention; the notion that low serotonin levels might be correlated with a tendency towards violence has surfaced in the popular press. The problem is that it is not the absence or low amount of serotonin per se that "causes" a certain manifestation. Serotonin is part of an exceedingly complicated mechanism which operates at the level of molecules, synapses, local circuits and systems, and in which sociocultural factors, past and present, also intervene powerfully. A satisfactory explanation can arise only from a more comprehensive view of the entire process, in which the relevant variables of a specific problem, such as depression or social adaptability, are analyzed in detail.

Mindful yogurt manufacturers often use bacteria that produce more dextrorotatory (right-turning) than levorotatory (left-turning) lactic acids. Molecules of the two kinds of lactic acid are mirror images of each other. Feeding the human digestive system with levorotatory lactic acid molecules is like giving a left-handed pair of scissors to a right-handed person: they’re hard to handle. That is why it is a good idea to pick yogurt from the supermarket shelves that states on the container: “Contains mainly dextrorotatory [or right-turning] lactic acid.

From an evolutionary standpoint, food that you don’t have is critically different from food that you do have. It’s the same for water, shelter, and tools. The division is so fundamental that separate pathways and chemicals evolved in the brain to handle peripersonal and extrapersonal space. When you look down, you look into the peripersonal space, and for that the brain is controlled by a host of chemicals concerned with experience in the here and now. But when the brain is engaged with the extrapersonal space, one chemical exercises more control than all the others, the chemical associated with anticipation and possibility: dopamine. Things in the distance, things we don’t have yet, cannot be used or consumed, only desired. Dopamine has a very specific job: maximizing resources that will be available to us in the future; the pursuit of better things.

When scientists underestimate complexity, they fall prey to the perils of unintended consequences. The parables of such scientific overreach are well-known: foreign animals, introduced to control pests, become pests in their own right; the raising of smokestacks, meant to alleviate urban pollution, releases particulate effluents higher in the air and exacerbates pollution; stimulating blood formation, meant to prevent heart attacks, thickens the blood and results in an increased risk of blood clots in the heart. But when nonscientists overestimate [italicized, sic] complexity- 'No one can possibly crack this [italicized, sic] code" - they fall into the trap of unanticipated consequences. In the early 1950s , a common trope among some biologists was that the genetic code would be so context dependent- so utterly determined by a particular cell in a particular organism and so horribly convoluted- that deciphering it would be impossible. The truth turned out to be quite the opposite: just one molecule carries the code, and just one code pervades the biological world. If we know the code, we can intentionally alter it in organisms, and ultimately in humans. Similarly, in the 1960s, many doubted that gene-cloning technologies could so easily shuttle genes between species. by 1980, making a mammalian protein in a bacterial cell, or a bacterial protein in a mammalian cell, was not just feasible, it was in Berg's words, rather "ridiculously simple." Species were specious. "Being natural" was often "just a pose.

The revelation that there was nothing "special" about humanity didn't shock her. Not specifically. She'd always been cynical about that sort of thing. The idea that reality was all too big to even quantify in any meaningful way didn't disturb her much either. Except, deep down, she'd assumed there was some inherent logic at work. Like ricocheting molecules congealing into planets and stars, dogs and cats. At least the made sense, even if it wasn't very comforting. At least it put things in neat little boxes with neat little labels that she didn't always understand but could rely on in terms of familiarity.

The face that Moses had begged to see – was forbidden to see – was slapped bloody (Exodus 33:19-20) The thorns that God had sent to curse the earth’s rebellion now twisted around his brow… “On your back with you!” One raises a mallet to sink the spike. But the soldier’s heart must continue pumping as he readies the prisoner’s wrist. Someone must sustain the soldier’s life minute by minute, for no man has this power on his own. Who supplies breath to his lungs? Who gives energy to his cells? Who holds his molecules together? Only by the Son do “all things hold together” (Colossians 1:17). The victim wills that the soldier live on – he grants the warrior’s continued existence. The man swings. As the man swings, the Son recalls how he and the Father first designed the medial nerve of the human forearm – the sensations it would be capable of. The design proves flawless – the nerves perform exquisitely. “Up you go!” They lift the cross. God is on display in his underwear and can scarcely breathe. But these pains are a mere warm-up to his other and growing dread. He begins to feel a foreign sensation. Somewhere during this day an unearthly foul odor began to waft, not around his nose, but his heart. He feels dirty. Human wickedness starts to crawl upon his spotless being – the living excrement from our souls. The apple of his Father’s eye turns brown with rot. His Father! He must face his Father like this! From heaven the Father now rouses himself like a lion disturbed, shakes His mane, and roars against the shriveling remnant of a man hanging on a cross.Never has the Son seen the Father look at him so, never felt even the least of his hot breath. But the roar shakes the unseen world and darkens the visible sky. The Son does not recognize these eyes. “Son of Man! Why have you behaved so? You have cheated, lusted, stolen, gossiped – murdered, envied, hated, lied. You have cursed, robbed, over-spent, overeaten – fornicated, disobeyed, embezzled, and blasphemed. Oh the duties you have shirked, the children you have abandoned! Who has ever so ignored the poor, so played the coward, so belittled my name? Have you ever held a razor tongue? What a self-righteous, pitiful drunk – you, who moles young boys, peddle killer drugs, travel in cliques, and mock your parents. Who gave you the boldness to rig elections, foment revolutions, torture animals, and worship demons? Does the list never end! Splitting families, raping virgins, acting smugly, playing the pimp – buying politicians, practicing exhortation, filming pornography, accepting bribes. You have burned down buildings, perfected terrorist tactics, founded false religions, traded in slaves – relishing each morsel and bragging about it all. I hate, loathe these things in you! Disgust for everything about you consumes me! Can you not feel my wrath? Of course the Son is innocent He is blamelessness itself. The Father knows this. But the divine pair have an agreement, and the unthinkable must now take place. Jesus will be treated as if personally responsible for every sin ever committed. The Father watches as his heart’s treasure, the mirror image of himself, sinks drowning into raw, liquid sin. Jehovah’s stored rage against humankind from every century explodes in a single direction. “Father! Father! Why have you forsaken me?!” But heaven stops its ears. The Son stares up at the One who cannot, who will not, reach down or reply. The Trinity had planned it. The Son had endured it. The Spirit enabled Him. The Father rejected the Son whom He loved. Jesus, the God-man from Nazareth, perished. The Father accepted His sacrifice for sin and was satisfied. The Rescue was accomplished.

The case I’ve presented in this book suggests that humans are undergoing what biologists call a major transition. Such transitions occur when less complex forms of life combine in some way to give rise to more complex forms. Examples include the transition from independently replicating molecules to replicating packages called chromosomes or, the transition from different kinds of simple cells to more complex cells in which these once-distinct simple cell types came to perform critical functions and become entirely mutually interdependent, such as the nucleus and mitochondria in our own cells. Our species’ dependence on cumulative culture for survival, on living in cooperative groups, on alloparenting and a division of labor and information, and on our communicative repertoires mean that humans have begun to satisfy all the requirements for a major biological transition. Thus, we are literally the beginnings of a new kind of animal.1 By contrast, the wrong way to understand humans is to think that we are just a really smart, though somewhat less hairy, chimpanzee. This view is surprisingly common. Understanding how this major transition is occurring alters how we think about the origins of our species, about the reasons for our immense ecological success, and about the uniqueness of our place in nature. The insights generated alter our understandings of intelligence, faith, innovation, intergroup competition, cooperation, institutions, rituals, and the psychological differences between populations. Recognizing that we are a cultural species means that, even in the short run (when genes don’t have enough time to change), institutions, technologies, and languages are coevolving with psychological biases, cognitive abilities, emotional responses, and preferences. In the longer run, genes are evolving to adapt to these culturally constructed worlds, and this has been, and is now, the primary driver of human genetic evolution. Figure 17.1.

Influenza is caused by three types of viruses, of which the most worrisome and widespread is influenza A. Viruses of that type all share certain genetic traits: a single-stranded RNA genome, which is partitioned into eight segments, which serve as templates for eleven different proteins. In other words, they have eight discrete stretches of RNA coding, linked together like eight railroad cars, with eleven different deliverable cargoes. The eleven deliverables are the molecules that comprise the structure and functional machinery of the virus. They are what the genes make. Two of those molecules become spiky protuberances from the outer surface of the viral envelope: hemagglutinin and neuraminidase. Those two, recognizable by an immune system, and crucial for penetrating and exiting cells of a host, give the various subtypes of influenza A their definitive labels: H5N1, H1N1, and so on. The term “H5N1” indicates a virus featuring subtype 5 of the hemagglutinin protein combined with subtype 1 of the neuraminidase protein. Sixteen different kinds of hemagglutinin, plus nine kinds of neuraminidase, have been detected in the natural world. Hemagglutinin is the key that unlocks a cell membrane so that the virus can get in, and neuraminidase is the key for getting back out. Okay so far? Having absorbed this simple paragraph, you understand more about influenza than 99.9 percent of the people on Earth. Pat yourself on the back and get a flu shot in November. At

What do you mean, words whose meanings evolved?" asked Alif. "That doesn't make sense. The Quran is the Quran." Vikram folded his legs-Alif did not watch this operation closely-and smiled at his audience. "The convert will understand. How do they translate ذرة in your English interpretation?" "Atom," said the convert. You don't find that strange, considering atoms were unknown in the sixth century?" The convert chewed her lip. "I never thought of that," she said. "You're right. There's no way atom is the original meaning of that word." "Ah." Vikram held up two fingers in a sign of benediction. He looked, Alif thought, like some demonic caricature of a saint. "But it is. In the twentieth century, atom became the original meaning of ذرة, because an atom was the tiniest object known to man. Then man split the atom. Today, the original meaning might be hadron. But why stop there? Tomorrow, it might be quark. In a hundred years, some vanishingly small object so foreign to the human mind that only Adam remembers its name. Each of those will be the original meaning of ذرة. Alif snorted. "That's impossible. ذرة must refer to some fundamental thing. It's attached to an object." "Yes it is. The smallest indivisible particle. That is the meaning packaged in the word. No part of it lifts out-it does not mean smallest, nor indivisible, nor particle, but all those things at once. Thus, in man's infancy, ذرة was a grain of sand. Then a mote of dust. Then a cell. Then a molecule. Then an atom. And so on. Man's knowledge of the universe may grow, but ذرة does not change." "That's..."The convert trailed off, looking lost. "Miraculous. Indeed.

The discovery of an interaction among the four hemes made it obvious that they must be touching, but in science what is obvious is not necessarily true. When the structure of hemoglobin was finally solved, the hemes were found to lie in isolated pockets on the surface of the subunits. Without contact between them how could one of them sense whether the others had combined with oxygen? And how could as heterogeneous a collection of chemical agents as protons, chloride ions, carbon dioxide, and diphosphoglycerate influence the oxygen equilibrium curve in a similar way? It did not seem plausible that any of them could bind directly to the hemes or that all of them could bind at any other common site, although there again it turned out we were wrong. To add to the mystery, none of these agents affected the oxygen equilibrium of myoglobin or of isolated subunits of hemoglobin. We now know that all the cooperative effects disappear if the hemoglobin molecule is merely split in half, but this vital clue was missed. Like Agatha Christie, Nature kept it to the last to make the story more exciting. There are two ways out of an impasse in science: to experiment or to think. By temperament, perhaps, I experimented, whereas Jacques Monod thought.

Days after the elections of 2016, asha sent me a link to a talk by astrophysicist Neil deGrasse Tyson. We have to have hope, she says to me across 3,000 miles, she in Brooklyn, me in Los Angeles. We listen together as Dr. deGrasse Tyson explains that the very atoms and molecules in our bodies are traceable to the crucibles in the centers of stars that once upon a time exploded into gas clouds. And those gas clouds formed other stars and those stars possessed the divine-right mix of properties needed to create not only planets, including our own, but also people, including us, me and her. He is saying that not only are we in the universe, but that the universe is in us. He is saying that we, human beings, are literally made out of stardust. And I know when I hear Dr. deGrasse Tyson say this that he is telling the truth because I have seen it since I was a child, the magic, the stardust we are, in the lives of the people I come from. I watched it in the labor of my mother, a Jehovah's Witness and a woman who worked two and sometimes three jobs at a time, keeping other people's children, working the reception desks at gyms, telemarketing, doing anything and everything for 16 hours a day the whole of my childhood in the Van Nuys barrio where we lived. My mother, cocoa brown and smooth, disowned by her family for the children she had as a very young and unmarried woman. My mother, never giving up despite never making a living wage. I saw it in the thin, brown face of my father, a boy out of Cajun country, a wounded healer, whose addictions were borne of a world that did not love him and told him so not once but constantly. My father, who always came back, who never stopped trying to be a version of himself there were no mirrors for. And I knew it because I am the thirteenth-generation progeny of a people who survived the hulls of slave ships, survived the chains, the whips, the months laying in their own shit and piss. The human beings legislated as not human beings who watched their names, their languages, their Goddesses and Gods, the arc of their dances and beats of their songs, the majesty of their dreams, their very families snatched up and stolen, disassembled and discarded, and despite this built language and honored God and created movement and upheld love. What could they be but stardust, these people who refused to die, who refused to accept the idea that their lives did not matter, that their children's lives did not matter?

Humans are organisms, subject to physical laws, including, alas, the one that says entropy always increases. Diseases are molecules misbehaving; the basic requirement of life is metabolism, and death its cessation. While all doctors treat diseases, neurosurgeons work in the crucible of identity: every operation on the brain is, by necessity, a manipulation of the substance of our selves, and every conversation with a patient undergoing brain surgery cannot help but confront this fact. In addition, to the patient and family, the brain surgery is usually the most dramatic event they have ever faced and, as such, has the impact of any major life event. At those critical junctures, the question is not simply whether to live or die but what kind of life is worth living. Would you trade your ability—or your mother’s—to talk for a few extra months of mute life? The expansion of your visual blind spot in exchange for eliminating the small possibility of a fatal brain hemorrhage? Your right hand’s function to stop seizures? How much neurologic suffering would you let your child endure before saying that death is preferable? “Because the brain mediates our experience of the world, any neurosurgical problem forces a patient and family, ideally with a doctor as a guide, to answer this question: What makes life meaningful enough to go on living?

The conceptual problem at the center of contemporary healthcare is the confusion between disease processes and disease origins. Instead of asking why an illness occurs and trying to remove the conditions that led to it, medical researchers try to understand the mechanisms through which the disease operates, so that they can then interfere with them. These mechanisms, rather than the true origins, are seen as the causes of disease in current medical thinking. In the process of reducing illness to disease, the attention of physicians has moved away from the patient as a whole person. By concentrating on smaller and smaller fragments of the body – shifting its perspective from the study of bodily organs and their functions to that of cells and, finally, to the study of molecules – modern medicine often loses sight of the human being, and having reduced health to mechanical functioning, it is no longer able to deal with the phenomenon of healing. Over the past four decades, the dissatisfaction with the mechanistic approach to health and healthcare has grown rapidly both among healthcare professionals and the general public. At the same time, the emerging systems view of life has given rise to a corresponding systems view of health, as we discuss in Chapter 15, while health consciousness among the general population has increased dramatically in many countries. The

We have come to understand the phenomena of life only as an assemblage of the lifeless. We take the mechanistic abstractions of our technical calculation to be ultimately concrete and "fundamentally real," while our most intimate experiences are labelled "mere appearance" and something having reality only within the closet of the isolated mind. Suppose however we were to invert this whole scheme, reverse the order in which it assigns abstract and concrete. What is central to our experience, then, need not be peripheral to nature. This sunset now, for example, caught within the network of bare winter branches, seems like a moment of benediction in which the whole of nature collaborates. Why should not these colours and these charging banners of light be as much a part of the universe as the atoms and molecules that make them up? If they were only "in my mind," then I and my mind would no longer be a part of nature. Why should the pulse of life toward beauty and value not be a part of things? Following this path, we do not vainly seek to assemble the living out of configurations of dead stuff, but we descend downwards from more complex to simpler grades of the organic. From humans to trees to rocks; from "higher grade" to "lower grade" organisms. In the universe of energy, any individual thing is a pattern of activity within the flux, and thereby an organism at some level.

Carbohydrates are not required in a healthy human diet. Another way to say this (as proponents of carbohydrate restriction have) is that there is no such thing as an essential carbohydrate. Nutritionists will say that 120 to 130 grams of carbohydrates are required in a healthy diet, but this is because they confuse what the brain and central nervous system will burn for fuel when diets are carbohydrate rich—120 to 130 grams daily—with what we actually have to eat. If there are no carbohydrates in the diet, the brain and central nervous system will run on molecules called “ketones.” These are synthesized in the liver from the fat we eat and from fatty acids, mobilized from the fat tissue because we’re not eating carbohydrates and insulin levels are low, and even from some amino acids. With no carbohydrates in the diet, ketones will provide roughly three-quarters of the energy that our brains use. And this is why severely carbohydrate-restricted diets are known as “ketogenic” diets. The rest of the energy required will come from glycerol, which is also being released from the fat tissue when the triglycerides are broken down into their component parts, and from glucose synthesized in the liver from the amino acids in protein. Because a diet that doesn’t include fattening carbohydrates will still include plenty of fat and protein, there will be no shortage of fuel for the brain.

Order Out of Chaos ... At the right temperature ... two peptide molecules will stay together long enough on average to find a third. Then the little trio finds a fourth peptide to attract into the little huddle, just through the random side-stepping and tumbling induced by all the rolling water molecules. Something extraordinary is happening: a larger structure is emerging from a finer system, not in spite of the chaotic and random motion of that system but because of it. Without the chaotic exploration of possibilities, the rare peptide molecules would never find each other, would never investigate all possible ways of aggregating so that the tape-like polymers emerge as the most likely assemblies. It is because of the random motion of all the fine degrees of freedom that the emergent, larger structures can assume the form they do. Even more is true when the number of molecules present becomes truly enormous, as is automatically the case for any amount of matter big enough to see. Out of the disorder emerges a ... pattern of emergent structure from a substrate of chaos.... The exact pressure of a gas, the emergence of fibrillar structures, the height in the atmosphere at which clouds condense, the temperature at which ice forms, even the formation of the delicate membranes surrounding every living cell in the realm of biology -- all this beauty and order becomes both possible and predictable because of the chaotic world underneath them.... Even the structures and phenomena that we find most beautiful of all, those that make life itself possible, grow up from roots in a chaotic underworld. Were the chaos to cease, they would wither and collapse, frozen rigid and lifeless at the temperatures of intergalactic space. This creative tension between the chaotic and the ordered lies within the foundations of science today, but it is a narrative theme of human culture that is as old as any. We saw it depicted in the ancient biblical creation narratives of the last chapter, building through the wisdom, poetic and prophetic literature. It is now time to return to those foundational narratives as they attain their climax in a text shot through with the storm, the flood and the earthquake, and our terrifying ignorance in the face of a cosmos apparently out of control. It is one of the greatest nature writings of the ancient world: the book of Job.

The difference between supermind and Big Mind (if we take Big Mind to mean the state experience of nondual Suchness, or turiyatita) is that Big Mind can be experienced or recognized at virtually any lower level or rung. Magic to Integral. In fact, one can be at, say, the Pluralistic stage, and experience several core characteristics of the entire sequence of state-stages (gross to subtle to causal to Witnessing to Nondual), although, of course, the entire sequence, including nondual Suchness, will be interpreted in Pluralistic terms. This is unfortunate in many ways—interpreting Dharma in merely Pluralistic terms (or Mythic terms, or Rational, and so on)—because it is so ultimately reductionistic; but it happens all the time, given the relative independence of states and structures at 1st and 2nd tier. Supermind, on the other hand, as a basic structure-rung (conjoined with nondual Suchness) can only be experienced once all the previous junior levels have emerged and developed, and as in all structure development, stages cannot be skipped. Therefore, unlike Big Mind, supermind can only be experienced after all 1st-, 2nd-, and 3rd-tier junior stages have been passed through. While, as Genpo Roshi has abundantly demonstrated, Big Mind state experience is available to virtually anybody at almost any age (and will be interpreted according to the View of their current stage), supermind is an extremely rare recognition. Supermind, as the highest structure-rung to date, has access to all previous structures, all the way back to Archaic—and the Archaic itself, of course, has transcended and included, and now embraces, every major structural evolution going all the way back to the Big Bang. (A human being literally enfolds and embraces all the major transformative unfoldings of the entire Kosmic history—strings to quarks to subatomic particles to atoms to molecules to cells, all the way through the Tree of Life up to its latest evolutionary emergent, the triune brain, the most complex structure in the known natural world.) Supermind, in any given individual, is experienced as a type of “omniscience”—the supermind, since it transcends and includes all of the previous structure-rungs, and inherently is conjoined with the highest nondual Suchness state, has a full and complete knowledge of all of the potentials in that person. It literally “knows all,” at least for the individual.

But our Edenic tent–God doesn’t just want to save us. He actually wants to be with us. He doesn’t just love us. God actually likes us. So God removes His royal robes and steps down from His throne to experience—for the first time—what it is like to be human. God is omniscient, which means that He is all-knowing. There’s nothing in the universe, no piece of information, no fact, no statistic that He doesn’t know. The hairs on your head, the zits on your face—He knows about every one. But until the incarnation, God hadn’t experienced human nature. Since zits aren’t a sin, perhaps Jesus had them too. God knows every hair on your head, but through the incarnation, God knows what it feels like to have hair ripped out. God knows about tiredness, but through the incarnation, He experiences exhaustion. God knows how many molecules it takes to shoot a hunger pain from your stomach to your brain. But through the incarnation, God knows what it feels like to starve to the point of death. Through the incarnation, God has enjoyed the same warm wave of sunlight that splashes across your face on the first day of spring. When you bathe in it, God smiles because He’s bathed in it too. He’s been refreshed by a night’s sleep after a long day of work. Warmed by a toasty bed on a cold winter night. Enjoyed a rich glass of wine while celebrating among friends. God authored creation. But through the incarnation, God experienced creation. And He encountered joy under the bridge. He also experienced pain. Relational, psychological, emotional, and physical agony. God has suffered the misery and brokenness of the same sin-saturated world that oppresses us every day. The pain of being rejected, beaten, abused, unloved, uncared for, mocked, shamed, spat upon, and disrespected as an image bearer of the Creator. Jesus knows all of this. He’s experienced all of this. And He willingly endured it to bring you back to Eden.

Among the most virulent of all such cultural parasite-equivalents is the religion-based denial of organic evolution. About one-half of Americans (46 percent in 2013, up from 44 percent in 1980), most of whom are evangelical Christians, together with a comparable fraction of Muslims worldwide, believe that no such process has ever occurred. As Creationists, they insist that God created humankind and the rest of life in one to several magical mega-strokes. Their minds are closed to the overwhelming mass of factual demonstrations of evolution, which is increasingly interlocked across every level of biological organization from molecules to ecosystem and the geography of biodiversity. They ignore, or more precisely they call it virtue to remain ignorant of, ongoing evolution observed in the field and even traced to the genes involved. Also looked past are new species created in the laboratory. To Creationists, evolution is at best just an unproven theory. To a few, it is an idea invented by Satan and transmitted through Darwin and later scientists in order to mislead humanity. When I was a small boy attending an evangelical church in Florida, I was taught that the secular agents of Satan are extremely bright and determined, but liars all, man and woman, and so no matter what I heard I must stick my fingers in my ears and hold fast to the true faith. We are all free in a democracy to believe whatever we wish, so why call any opinion such as Creationism a virulent cultural parasite-equivalent? Because it represents a triumph of blind religious faith over carefully tested fact. It is not a conception of reality forged by evidence and logical judgment. Instead, it is part of the price of admission to a religious tribe. Faith is the evidence given of a person’s submission to a particular god, and even then not to the deity directly but to other humans who claim to represent the god. The cost to society as a whole of the bowed head has been enormous. Evolution is a fundamental process of the Universe, not just in living organisms but everywhere, at every level. Its analysis is vital to biology, including medicine, microbiology, and agronomy. Furthermore psychology, anthropology, and even the history of religion itself make no sense without evolution as the key component followed through the passage of time. The explicit denial of evolution presented as a part of a “creation science” is an outright falsehood, the adult equivalent of plugging one’s ears, and a deficit to any society that chooses to acquiesce in this manner to a fundamentalist faith.

I am, reluctantly, a self-confessed carbon chauvinist. Carbon is abundant in the Cosmos. It makes marvelously complex molecules, good for life. I am also a water chauvinist. Water makes an ideal solvent system for organic chemistry to work in and stays liquid over a wide range of temperatures. But sometimes I wonder. Could my fondness for materials have something to do with the fact that I am made chiefly of them? Are we carbon- and water-based because those materials were abundant on the Earth at the time of the origin of life? Could life elsewhere—on Mars, say—be built of different stuff? I am a collection of water, calcium and organic molecules called Carl Sagan. You are a collection of almost identical molecules with a different collective label. But is that all? Is there nothing in here but molecules? Some people find this idea somehow demeaning to human dignity. For myself, I find it elevating that our universe permits the evolution of molecular machines as intricate and subtle as we. But the essence of life is not so much the atoms and simple molecules that make us up as the way in which they are put together. Every now and then we read that the chemicals which constitute the human body cost ninety-seven cents or ten dollars or some such figure; it is a little depressing to find our bodies valued so little. However, these estimates are for human beings reduced to our simplest possible components. We are made mostly of water, which costs almost nothing; the carbon is costed in the form of coal; the calcium in our bones as chalk; the nitrogen in our proteins as air (cheap also); the iron in our blood as rusty nails. If we did not know better, we might be tempted to take all the atoms that make us up, mix them together in a big container and stir. We can do this as much as we want. But in the end all we have is a tedious mixture of atoms. How could we have expected anything else? Harold Morowitz has calculated what it would cost to put together the correct molecular constituents that make up a human being by buying the molecules from chemical supply houses. The answer turns out to be about ten million dollars, which should make us all feel a little better. But even then we could not mix those chemicals together and have a human being emerge from the jar. That is far beyond our capability and will probably be so for a very long period of time. Fortunately, there are other less expensive but still highly reliable methods of making human beings. I think the lifeforms on many worlds will consist, by and large, of the same atoms we have here, perhaps even many of the same basic molecules, such as proteins and nucleic acids—but put together in unfamiliar ways. Perhaps organisms that float in dense planetary atmospheres will be very much like us in their atomic composition, except they might not have bones and therefore not need much calcium. Perhaps elsewhere some solvent other than water is used. Hydrofluoric acid might serve rather well, although there is not a great deal of fluorine in the Cosmos; hydrofluoric acid would do a great deal of damage to the kind of molecules that make us up, but other organic molecules, paraffin waxes, for example, are perfectly stable in its presence. Liquid ammonia would make an even better solvent system, because ammonia is very abundant in the Cosmos. But it is liquid only on worlds much colder than the Earth or Mars. Ammonia is ordinarily a gas on Earth, as water is on Venus. Or perhaps there are living things that do not have a solvent system at all—solid-state life, where there are electrical signals propagating rather than molecules floating about. But these ideas do not

EAGLE The East direction is represented by eagle and condor, who bring vision, clarity, and foresight. Eagle perceives the entire panorama of life without becoming bogged down in its details. The energies of eagle assist us in finding the guiding vision of our lives. The eyes of condor see into the past and the future, helping to know where we come from, and who we are becoming. When I work with a client who is stuck in the traumas of the past, I help her to connect with the spirit of eagle or condor. As this energy infuses the healing space, my client is often able to attain new clarity and insight into her life. This is not an intellectual insight, but rather a call, faint at first, hardly consciously heard. Her possibilities beckon to her and propel her out of her grief and into her destiny. I believe that while everyone has a future, only certain people have a destiny. Having a destiny means living to your fullest human potential. You don’t need to become a famous politician or poet, but your destiny has to be endowed with meaning and purpose. You could be a street sweeper and be living a destiny. You could be the president of a large corporation and be living a life bereft of meaning. One can make oneself available to destiny, but it requires a great deal of courage to do so. Otherwise our destiny bypasses us, leaving us deprived of a fulfillment known by those who choose to take the road less traveled. Eagle allows us to rise above the mundane battles that occupy our lives and consume our energy and attention. Eagle gives us wings to soar above trivial day-to-day struggles into the high peaks close to Heaven. Eagle and condor represent the self-transcending principle in nature. Biologists have identified the self-transcending principle as one of the prime agendas of evolution. Living molecules seek to transcend their selfhood to become cells, then simple organisms, which then form tissues, then organs, and then evolve into complex beings such as humans and whales. Every transcending jump is inclusive of all of the levels beneath it. Cells are inclusive of molecules, yet transcend them; organs are inclusive of cells, yet go far beyond them; whales are inclusive of organs yet cannot be described by them, as the whole transcends the sum of its parts. The transcending principle represented by eagle states that problems at a certain level are best solved by going up one step. The problems of cells are best resolved by organs, while the needs of organs are best addressed by an organism such as a butterfly or a human. The same principle operates in our lives. Think of nested Russian dolls. Material needs are the tiny doll in the center. The larger emotional doll encompasses them, and both are contained within the outermost spiritual doll. In this way, we cannot satisfy emotional needs with material things, but we can satisfy them spiritually. When we go one step up, our emotional needs are addressed in the solution. We rise above our life dilemmas on the wings of eagle and see our lives in perspective.

Near the exit to the blue patio, DeCoverley Pox and Joaquin Stick stand by a concrete scale model of the Jungfrau, ... socking the slopes of the famous mountain with red rubber hot-water bags full of ice cubes, the idea being to pulverize the ice for Pirate's banana frappes. With their nights' growths of beard, matted hair, bloodshot eyes, miasmata of foul breath, DeCoverley and Joaquin are wasted gods urging on a tardy glacier. Elsewhere in the maisonette, other drinking companions disentangle from blankets (one spilling wind from his, dreaming of a parachute), piss into bathroom sinks, look at themselves with dismay in concave shaving mirrors, slab water with no clear plan in mind onto heads of thinning hair, struggle into Sam Brownes, dub shoes against rain later in the day with hand muscles already weary of it, sing snatches of popular songs whose tunes they don't always know, lie, believing themselves warmed, in what patches of the new sunlight come between the mullions, begin tentatively to talk shop as a way of easing into whatever it is they'll have to be doing in less than an hour, lather necks and faces, yawn, pick their noses, search cabinets or bookcases for the hair of the dog that not without provocation and much prior conditioning bit them last night. Now there grows among all the rooms, replacing the night's old smoke, alcohol and sweat, the fragile, musaceous odor of Breakfast:flowery, permeating, surprising, more than the color of winter sunlight, taking over not so much through any brute pungency or volume as by the high intricacy to the weaving of its molecules, sharing the conjuror's secret by which-- though it is not often Death is told so clearly to fuck off--- the genetic chains prove labyrinthine enough to preserve some human face down ten or twenty generations. . . so the same assertion-through-structure allows this war morning's banana fragrance to meander, repossess, prevail. Is there any reason not to open every window, and let the kind scent blanket all Chelsea? As a spell, against falling objects. . . .

Flow is an extremely potent response to external events and requires an extraordinary set of signals. The process includes dopamine, which does more than tune signal-to-noise ratios. Emotionally, we feel dopamine as engagement, excitement, creativity, and a desire to investigate and make meaning out of the world. Evolutionarily, it serves a similar function. Human beings are hardwired for exploration, hardwired to push the envelope: dopamine is largely responsible for that wiring. This neurochemical is released whenever we take a risk or encounter something novel. It rewards exploratory behavior. It also helps us survive that behavior. By increasing attention, information flow, and pattern recognition in the brain, and heart rate, blood pressure, and muscle firing timing in the body, dopamine serves as a formidable skill-booster as well. Norepinephrine provides another boost. In the body, it speeds up heart rate, muscle tension, and respiration, and triggers glucose release so we have more energy. In the brain, norepinephrine increases arousal, attention, neural efficiency, and emotional control. In flow, it keeps us locked on target, holding distractions at bay. And as a pleasure-inducer, if dopamine’s drug analog is cocaine, norepinephrine’s is speed, which means this enhancement comes with a hell of a high. Endorphins, our third flow conspirator, also come with a hell of a high. These natural “endogenous” (meaning naturally internal to the body) opiates relieve pain and produce pleasure much like “exogenous” (externally added to the body) opiates like heroin. Potent too. The most commonly produced endorphin is 100 times more powerful than medical morphine. The next neurotransmitter is anandamide, which takes its name from the Sanskrit word for “bliss”—and for good reason. Anandamide is an endogenous cannabinoid, and similarly feels like the psychoactive effect found in marijuana. Known to show up in exercise-induced flow states (and suspected in other kinds), this chemical elevates mood, relieves pain, dilates blood vessels and bronchial tubes (aiding respiration), and amplifies lateral thinking (our ability to link disparate ideas together). More critically, anandamide also inhibits our ability to feel fear, even, possibly, according to research done at Duke, facilitates the extinction of long-term fear memories. Lastly, at the tail end of a flow state, it also appears (more research needs to be done) that the brain releases serotonin, the neurochemical now associated with SSRIs like Prozac. “It’s a molecule involved in helping people cope with adversity,” Oxford University’s Philip Cowen told the New York Times, “to not lose it, to keep going and try to sort everything out.” In flow, serotonin is partly responsible for the afterglow effect, and thus the cause of some confusion. “A lot of people associate serotonin directly with flow,” says high performance psychologist Michael Gervais, “but that’s backward. By the time the serotonin has arrived the state has already happened. It’s a signal things are coming to an end, not just beginning.” These five chemicals are flow’s mighty cocktail. Alone, each packs a punch, together a wallop.

Timeline of History Years Before the Present 13.5 billion Matter and energy appear. Beginning of physics. Atoms and molecules appear. Beginning of chemistry. 4.5 billion Formation of planet Earth. 3.8 billion Emergence of organisms. Beginning of biology. 6 million Last common grandmother of humans and chimpanzees. 2.5 million Evolution of the genus Homo in Africa. First stone tools. 2 million Humans spread from Africa to Eurasia. Evolution of different human species. 500,000 Neanderthals evolve in Europe and the Middle East. 300,000 Daily usage of fire. 200,000 Homo sapiens evolves in East Africa. 70,000 The Cognitive Revolution. Emergence of fictive language. Beginning of history. Sapiens spread out of Africa. 45,000 Sapiens settle Australia. Extinction of Australian megafauna. 30,000 Extinction of Neanderthals. 16,000 Sapiens settle America. Extinction of American megafauna. 13,000 Extinction of Homo floresiensis. Homo sapiens the only surviving human species. 12,000 The Agricultural Revolution. Domestication of plants and animals. Permanent settlements. 5,000 First kingdoms, script and money. Polytheistic religions. 4,250 First empire – the Akkadian Empire of Sargon. 2,500 Invention of coinage – a universal money. The Persian Empire – a universal political order ‘for the benefit of all humans’. Buddhism in India – a universal truth ‘to liberate all beings from suffering’. 2,000 Han Empire in China. Roman Empire in the Mediterranean. Christianity. 1,400 Islam. 500 The Scientific Revolution. Humankind admits its ignorance and begins to acquire unprecedented power. Europeans begin to conquer America and the oceans. The entire planet becomes a single historical arena. The rise of capitalism. 200 The Industrial Revolution. Family and community are replaced by state and market. Massive extinction of plants and animals. The Present Humans transcend the boundaries of planet Earth. Nuclear weapons threaten the survival of humankind. Organisms are increasingly shaped by intelligent design rather than natural selection. The Future Intelligent design becomes the basic principle of life? Homo sapiens is replaced by superhumans?

Historically, holism had been a break from the reductionist methods of science. Holism (...) is a way of viewing the universe as a web of interactions and relationships. Whole systems (and the universe can be seen as an overarching system of systems) have properties beyond those of their parts. All things are, in some sense, alive, or a part of a living system; the real world of mind and matter, body and consciousness, cannot be understood by reducing it to pieces and parts. 'Matter is mind' – this is perhaps the holists' quintessential belief. The founding theories of holism had tried to explain how mind emerges from the material universe, how the consciousness of all things is interconnected. The first science, of course, had failed utterly to do this. The first science had resigned human beings to acting as objective observers of a mechanistic and meaningless universe. A dead universe. The human mind, according to the determinists, was merely the by-product of brain chemistry. Chemical laws, the way the elements combine and interact, were formulated as complete and immutable truths. The elements themselves were seen as indivisible lumps of matter, devoid of consciousness, untouched and unaffected by the very consciousnesses seeking to understand how living minds can be assembled from dead matter. The logical conclusion of these assumptions and conceptions was that people are like chemical robots possessing no free will. No wonder the human race, during the Holocaust Century, had fallen into insanity and despair. Holism had been an attempt to restore life to this universe and to reconnect human beings with it. To heal the split between self and other. (...) Each quantum event, each of the trillions of times reality's particles interact with each other every instant, is like a note that rings and resonates throughout the great bell of creation. And the sound of the ringing propagates instantaneously, everywhere at once, interconnecting all things. This is a truth of our universe. It is a mystical truth, that reality at its deepest level is an undivided wholeness. It has been formalized and canonized, and taught to the swarms of humanity searching for a fundamental unity. Only, human beings have learned it as a theory and a doctrine, not as an experience. A true holism should embrace not only the theory of living systems, but also the reality of the belly, of wind, hunger, and snowworms roasting over a fire on a cold winter night. A man or woman (or child) to be fully human, should always marvel at the mystery of life. We each should be able to face the universe and drink in the stream of photons shimmering across the light-distances, to listen to the ringing of the farthest galaxies, to feel the electrons of each haemoglobin molecule spinning and vibrating deep inside the blood. No one should ever feel cut off from the ocean of mind and memory surging all around; no one should ever stare up at the icy stars and feel abandoned or alone. It was partly the fault of holism that a whole civilization had suffered the abandonment of its finest senses, ten thousand trillion islands of consciousness born into the pain and promise of neverness, awaiting death with glassy eyes and murmured abstractions upon their lips, always fearing life, always longing for a deeper and truer experience of living.