Hormone Related Quotes

So you love me," said Petra softly when the kiss ended. I'm a raging mass of hormones thet I'm too young to understand," said Bean. "You're a female of a closely related species. According to all the best primatologists, I really have no choice." That's nice," she said...

Doc begs me for the wires to fix the pump. We should at least keep putting the hormones in the water," he insists, "so that they don't start mating with relatives." "Most people don't want to commit incest," I say dryly.

Oxytocin, a hormone and neuropeptide ... plays a major role in attachment processes and serves several purposes: It causes women to go into labor, strengthens attachment, and ... [increases] trust and cooperation. We get a boost of oxytocin in our brain during orgasm and even when we cuddle -- which is why it's been tagged the "cuddle hormone." How is oxytocin related to conflict reduction? Sometimes we spend less quality time with our partner -- especially when other demands on us are pressing. However, neuroscience findings suggest that we should change our priorities. By forgoing closeness with our partners, we are also missing our oxytocin boost -- making us less agreeable to the world around us and more vulnerable to conflict.

I am often described to my irritation as a 'contrarian' and even had the title inflicted on me by the publisher of one of my early books. (At least on that occasion I lived up to the title by ridiculing the word in my introduction to the book's first chapter.) It is actually a pity that our culture doesn't have a good vernacular word for an oppositionist or even for someone who tries to do his own thinking: the word 'dissident' can't be self-conferred because it is really a title of honor that has to be won or earned, while terms like 'gadfly' or 'maverick' are somehow trivial and condescending as well as over-full of self-regard. And I've lost count of the number of memoirs by old comrades or ex-comrades that have titles like 'Against the Stream,' 'Against the Current,' 'Minority of One,' 'Breaking Ranks' and so forth—all of them lending point to Harold Rosenberg's withering remark about 'the herd of independent minds.' Even when I was quite young I disliked being called a 'rebel': it seemed to make the patronizing suggestion that 'questioning authority' was part of a 'phase' through which I would naturally go. On the contrary, I was a relatively well-behaved and well-mannered boy, and chose my battles with some deliberation rather than just thinking with my hormones.

The most common theory points to the fact that men are stronger than women and that they have used their greater physical power to force women into submission. A more subtle version of this claim argues that their strength allows men to monopolize tasks that demand hard manual labor, such as plowing and harvesting. This gives them control of food production, which in turn translates into political clout. There are two problems with this emphasis on muscle power. First, the statement that men are stronger is true only on average and only with regard to certain types of strength. Women are generally more resistant to hunger, disease, and fatigue than men. There are also many women who can run faster and lift heavier weights than many men. Furthermore, and most problematically for this theory, women have, throughout history, mainly been excluded from jobs that required little physical effort, such as the priesthood, law, and politics, while engaging in hard manual labor in the fields....and in the household. If social power were divided in direct relation to physical strength or stamina, women should have got far more of it. Even more importantly, there simply is no direct relation between physical strength and social power among humans. People in their sixties usually exercise power over people in their twenties, even though twenty-somethings are much stronger than their elders. ...Boxing matches were not used to select Egyptian pharaohs or Catholic popes. In forager societies, political dominance generally resides with the person possessing the best social skills rather than the most developed musculature. In fact, human history shows that there is often an inverse relation between physical prowess and social power. In most societies, it’s the lower classes who do the manual labor. Another theory explains that masculine dominance results not from strength but from aggression. Millions of years of evolution have made men far more violent than women. Women can match men as far as hatred, greed, and abuse are concern, but when push comes to shove…men are more willing to engage in raw physical violence. This is why, throughout history, warfare has been a masculine prerogative. In times of war, men’s control of the armed forces has made them the masters of civilian society too. They then use their control of civilian society to fight more and more wars. …Recent studies of the hormonal and cognitive systems of men and women strengthen the assumption that men indeed have more aggressive and violent tendencies and are…on average, better suited to serve as common soldiers. Yet, granted that the common soldiers are all men, does it follow that the ones managing the war and enjoying its fruits must also be men? That makes no sense. It’s like assuming that because all the slaves cultivating cotton fields are all Black, plantation owners will be Black as well. Just as an all-Black workforce might be controlled by an all-White management, why couldn’t an all-male soldiery be controlled by an all-female government?

I was (an am) unsure about how I am related to my old self, or to myself from year to year. The hormonal profile of an individual determines much of the manifest personality. If you skew the endocrine system,you loose the pathways to the self. When endocrine patterns change it alters the way you think and feel. One shift in the pattern tends to trip another.

There was something awful about feeling rage and wanting to strangle something but instead falling prey to the softness of hormones, welling up with the inadequacy of sadness when what she meant to do was scream.

Relatively small changes in genes, hormones and neurons were enough to transform Homo erectus – who could produce nothing more impressive than flint knives – into Homo sapiens, who produce spaceships and computers.

Phosphatidylserine is a natural constituent of the cell membrane but is found in especially high concentrations in the brain. Supplementing with phosphatidylserine slows down memory loss and has been shown to reverse memory loss in some patients with age-related memory decline. It also lowers levels of cortisol, a principal hormone of aging.

The study reported a 24 percent relative increase in the risk of breast cancer among a subset of women taking HRT, and headlines all over the world condemned HRT as a dangerous, cancer-causing therapy. All of a sudden, on the basis of this one study, hormone replacement treatment became virtually taboo. This reported 24 percent risk increase sounded scary indeed. But nobody seemed to care that the absolute risk increase of breast cancer for women in the study remained minuscule. Roughly five out of every one thousand women in the HRT group developed breast cancer, versus four out of every one thousand in the control group, who received no hormones.

Next is diet or nutrition—or as I prefer to call it, nutritional biochemistry. The third domain is sleep, which has gone underappreciated by Medicine 2.0 until relatively recently. The fourth domain encompasses a set of tools and techniques to manage and improve emotional health. Our fifth and final domain consists of the various drugs, supplements, and hormones that doctors learn about in medical school and beyond. I lump these into one bucket called exogenous molecules, meaning molecules we ingest that come from outside the body.

Sex Games: What Men Really Think About Sex Partners (Sexuality, Cheating

Well,’ Elodie said with a sigh, ‘since Hannah has successfully ruined the appetites of her male relatives, that means more dessert for us girls. We’re having sticky toffee pudding and ice cream.’ ‘Och … well … you know, I’m feeling much better all of a sudden.’ Adam gestured to Braden, whose cheeks had warmed at the mention of dessert. ‘I could go for some pudding.’ Braden nodded solemnly. ‘Funnily enough, me too.’ Determined to stock up on good food before I returned to my diet-food-laden fridge back at the flat, I wasn’t sure I wanted to share pudding with the boys. No, I wasn’t sure about that at all. I looked over at Hannah and asked evilly, ‘What was that about boobs and hormones?

In fact, according to physicians, the functioning of the digestion depends less on the brain than on hormonal mechanisms and autoregulators. However, during a fast, the digestive system gets an increasing rest. About ten hours after a meal, the contractions stop and the feeling of hunger disappears; five or six hours later the glucose stops coming directly from the intestines and begins to produce itself from the reserve of glycogen contained in the liver. From then on, the body works on itself in a closed circuit, becoming itself the source of the energy it uses. Instead of destroying an appropriating to himself nourishment taken from outside, man enters a state of nonviolence and detachment relative to the outside world.

Your waist size is such an important predictor of health because the type of fat that is stored around your waistline—called “visceral fat” or “belly fat”—is related to the release of proteins and hormones that cause inflammation, which can in turn damage your arteries and affect how you metabolize sugars and fats. For this reason, visceral fat is strongly linked to type 2 diabetes, heart disease, stroke, Alzheimer’s, and other chronic diseases. Seeing your waist size come down is a great indicator of improving health.

The industrial and technological revolutions have made our lives simpler, in terms of what is physically required of us on a daily basis, but they have also made it possible for us to do a whole lot less than we ought to be doing, and we suffer for it. We have become flabby and overweight; our joints and muscles have become stiff from lack of use. We suffer from all sorts of problems related to our lack of physical exercise; it affects us on all levels, causing high blood pressure, increased cholesterol, anxiety, depression, insomnia and the list goes on and on. We know, too, how much better we feel for a bit of exercise. Those “feel-good” hormones lift our spirits, boost self-esteem and improve our overall sense of well-being. It’s a sort of built-in reward system. There’s a reason for that. It’s because we are meant to be active.

The defenders of feeling-based marriage venerate emotions for their authenticity only because they avoid looking closely at what actually floats through most people's emotional kaleidoscopes, all the contradictory, sentimental, and hormonal forces that pull us in a hundred often crazed and inconclusive directions. We could not be fulfilled if we weren't inauthentic some of the time—inauthentic, that is, in relation to such things as our passing desires to throttle our children, poison our spouse, or end our marriage over a dispute about changing a lightbulb. A degree of repression is necessary for both the mental health of our species and the adequate functioning of a decently ordered society. We are chaotic chemical propositions. We should feel grateful for, and protected by, the knowledge that our external circumstances are often out of line with what we feel; it is a sign that we are probably on the right course.

In recent years, there has been an explosion of research into meditation, which has been shown to: • Reduce blood pressure • Boost recovery after the release of the stress hormone cortisol • Improve immune system functioning and response • Slow age-related atrophy of the brain • Mitigate the symptoms of depression and anxiety

Stress can also prevent extinction from taking place.53 This is thought to be due to the fact that stressful events release the hormone cortisol via the pituitary-adrenal system (see Chapter 3); this hormone has impairing effects on PFCVM function.54 Thus, the very factor needed to induce extinction—exposure to stressful threats—can prevent extinction. This is an argument against the use of flooding and related exposure procedures that elicit high levels of “fear.” However, the hormones released during stress that impair extinction have complex and sometimes opposing effects on different phases of learning (acquisition, memory consolidation, memory retrieval, extinction, and memory reconsolidation).

That means to push very heavy weight, repeatedly, and to constantly strive to elevate both your baseline numbers and the total weight lifted at the workout—until you start to reach a natural limit relative to your competitive goals. This will deliver improvements in strength and subsequent improvements in endurance performance, and also maximize the hormonal, anti-aging benefits of the workout.

Hormonal responses to various fetal and childhood experiences have epigenetic effects on genes related to the growth factor BDNF, to the vasopressin and oxytocin system, and to estrogen sensitivity. These effects are pertinent to adult cognition, personality, emotionality, and psychiatric health. Childhood abuse, for example, causes epigenetic changes in hundreds of genes in the human hippocampus.

The neurological research shows something truly remarkable: If a person keeps taking the same substance, his or her brain keeps firing the same circuits in the same way—in effect, memorizing what the substance does. The person can easily become conditioned to the effect of a particular pill or injection from associating it with a familiar internal change from past experience. Because of this kind of conditioning, when the person then takes a placebo, the same hardwired circuits will fire as when he or she took the drug. An associative memory elicits a subconscious program that makes a connection between the pill or injection and the hormonal change in the body, and then the program automatically signals the body to make the related chemicals found in the drug. . . . Isn’t that amazing? Benedetti

Oxytocin and vasopressin are chemically similar hormones; the DNA sequences that constitute their genes are similar, and the two genes occur close to each other on the same chromosome. There was a single ancestral gene that, a few hundred million years ago, was accidentally “duplicated” in the genome, and the DNA sequences in the two copies of the gene drifted independently, evolving into two closely related genes

controlling insulin levels adequately such that serum insulin levels remain low. In this way, hormone-sensitive lipase is easier to activate, making mobilized bodyfat the body’s primary energy source preferentially over other sources. This state can be achieved through a diet that is relatively restricted in carbohydrates, but one will have more dietary latitude if, in concert with going easy on the carbohydrates, one engages in the performance of high-intensity exercise.

Michael Pollan: "The industrialization--and dehumanization--of American animal farming is a relatively new, evitable, and local phenomenon: no other country raises and slaughters its food animals quite as intensively or as brutally as we do." U.S. consumers may take our pick of reasons to be wary of the resulting product: growth hormones, antibiotic-resistant bacteria, unhealthy cholesterol composition, deadly E. coli strains, fuel consumption, concentration of manure into toxic waste lagoons, and the turpitude of keeping confined creatures at the limits of their physiological and psychological endurance.

Our brains, for instance, are 70 percent fat, mostly in the form of a substance known as myelin that insulates nerve cells and, for that matter, all nerve endings in the body. Fat is the primary component of all cell membranes. Changing the proportion of saturated to unsaturated fats in the diet, as proponents of Keys’s hypothesis recommended, might well change the composition of the fats in the cell membranes. This could alter the permeability of cell membranes, which determines how easily they transport, among other things, blood sugar, proteins, hormones, bacteria, viruses, and tumor-causing agents into and out of the cell. The relative saturation of these membrane fats could affect the aging of cells and the likelihood that blood cells will clot in vessels and cause heart attacks.

Nobody is ever made happy by winning the lottery, buying a house, getting a promotion or even finding true love. People are made happy by one thing and one thing only – pleasant sensations in their bodies. A person who just won the lottery or found new love and jumps from joy is not really reacting to the money or the lover. She is reacting to various hormones coursing through her bloodstream and to the storm of electric signals flashing between different parts of her brain. Unfortunately for all hopes of creating heaven on earth, our internal biochemical system seems to be programmed to keep happiness levels relatively constant. There's no natural selection for happiness as such - a happy hermit's genetic line will go extinct as the genes of a pair of anxious parents get carried on to the next generation. Happiness and misery play a role in evolution only to the extent that they encourage or discourage survival and reproduction. Perhaps it's not surprising, then, that evolution has moulded us to be neither too miserable nor too happy. It enables us to enjoy a momentary rush of pleasant sensations, but these never last for ever. Sooner of later they subside and give place to unpleasant sensations. (...) Some scholars compare human biochemistry to an air-conditioning system that keeps the temperature constant, come heatwave or snowstorm. Events might momentarily change the temperature, but the air-conditioning system always returns the temperature to the same set point. Some air-conditioning systems are set at twenty-five degrees Celsius. Others are set at twenty degrees. Human happiness conditioning systems also differ from person to person. On a scale from one to ten, some people are born with a cheerful biochemical system that allows their mood to swing between levels six and ten, stabilising with time at eight. Such a person is quite happy even if she lives in an alienating big city, loses all her money in a stock-exchange crash and is diagnosed with diabetes. Other people are cursed with a gloomy biochemistry that swings between three and seven and stabilises at five. Such an unhappy person remains depressed even if she enjoys the support of a tight-knit community, wins millions in the lottery and is as healthy as an Olympic athlete (...) incapable of experiencing anything beyond level seven happiness. Her brain is simply not built for exhilaration, come what may. (...) Buying cars and writing novels do not change our biochemistry. They can startle it for a fleeting moment, but it is soon back to the set point.

It may seem paradoxical to claim that stress, a physiological mechanism vital to life, is a cause of illness. To resolve this apparent contradiction, we must differentiate between acute stress and chronic stress. Acute stress is the immediate, short-term body response to threat. Chronic stress is activation of the stress mechanisms over long periods of time when a person is exposed to stressors that cannot be escaped either because she does not recognize them or because she has no control over them. Discharges of nervous system, hormonal output and immune changes constitute the flight-or-fight reactions that help us survive immediate danger. These biological responses are adaptive in the emergencies for which nature designed them. But the same stress responses, triggered chronically and without resolution, produce harm and even permanent damage. Chronically high cortisol levels destroy tissue. Chronically elevated adrenalin levels raise the blood pressure and damage the heart. There is extensive documentation of the inhibiting effect of chronic stress on the immune system. In one study, the activity of immune cells called natural killer (NK) cells were compared in two groups: spousal caregivers of people with Alzheimer’s disease, and age- and health-matched controls. NK cells are front-line troops in the fight against infections and against cancer, having the capacity to attack invading micro-organisms and to destroy cells with malignant mutations. The NK cell functioning of the caregivers was significantly suppressed, even in those whose spouses had died as long as three years previously. The caregivers who reported lower levels of social support also showed the greatest depression in immune activity — just as the loneliest medical students had the most impaired immune systems under the stress of examinations. Another study of caregivers assessed the efficacy of immunization against influenza. In this study 80 per cent among the non-stressed control group developed immunity against the virus, but only 20 per cent of the Alzheimer caregivers were able to do so. The stress of unremitting caregiving inhibited the immune system and left people susceptible to influenza. Research has also shown stress-related delays in tissue repair. The wounds of Alzheimer caregivers took an average of nine days longer to heal than those of controls. Higher levels of stress cause higher cortisol output via the HPA axis, and cortisol inhibits the activity of the inflammatory cells involved in wound healing. Dental students had a wound deliberately inflicted on their hard palates while they were facing immunology exams and again during vacation. In all of them the wound healed more quickly in the summer. Under stress, their white blood cells produced less of a substance essential to healing. The oft-observed relationship between stress, impaired immunity and illness has given rise to the concept of “diseases of adaptation,” a phrase of Hans Selye’s. The flight-or-fight response, it is argued, was indispensable in an era when early human beings had to confront a natural world of predators and other dangers. In civilized society, however, the flight-fight reaction is triggered in situations where it is neither necessary nor helpful, since we no longer face the same mortal threats to existence. The body’s physiological stress mechanisms are often triggered inappropriately, leading to disease. There is another way to look at it. The flight-or-fight alarm reaction exists today for the same purpose evolution originally assigned to it: to enable us to survive. What has happened is that we have lost touch with the gut feelings designed to be our warning system. The body mounts a stress response, but the mind is unaware of the threat. We keep ourselves in physiologically stressful situations, with only a dim awareness of distress or no awareness at all.

Correlation and causality. Why is it that throughout the animal kingdom and in every human culture, males account for most aggression and violence? Well, what about testosterone and some related hormones, collectively called androgens, a term that unless otherwise noted, I will use simplistically as synonymous with testosterone. In nearly all species, males have more circulating testosterone than do females, who secrete small amounts of androgens from the adrenal glands. Moreover, male aggression is most prevalent when testosterone levels are highest; adolescence and during mating season in seasonal breeders. Thus, testosterone and aggression are linked. Furthermore, there are particularly high levels of testosterone receptors in the amygdala, in the way station by which it projects to the rest of the brain, the bed nucleus of the stria terminalis, and in its major targets, the hypothalamus, the central gray of the mid-brain, and the frontal cortex. But these are merely correlative data. Showing that testosterone causes aggression requires a subtraction plus a replacement experiment. Subtraction, castrate a male: do levels of aggression decrease? Yes, including in humans. This shows that something coming from the testes causes aggression. Is it testosterone? Replacement: give that castrated individual replacement testosterone. Do pre-castration levels of aggression return? Yes, including in humans, thus testosterone causes aggression. Time to see how wrong that is. The first hint of a complication comes after castration. When average levels of aggression plummet in every species, but crucially, not to zero, well, maybe the castration wasn't perfect, you missed some bits of testes, or maybe enough of the minor adrenal androgens are secreted to maintain the aggression. But no, even when testosterone and androgens are completely eliminated, some aggression remains, thus some male aggression is testosterone independent. This point is driven home by castration of some sexual offenders, a legal procedure in a few states. This is accomplished with chemical castration, administration of drugs that either inhibit testosterone production or block testosterone receptors. Castration decreases sexual urges in the subset of sex offenders with intense, obsessive, and pathological urges. But otherwise, castration doesn't decrease recidivism rates as stated in one meta-analysis. Hostile rapists and those who commit sex crimes motivated by power or anger are not amenable to treatment with the anti-androgenic drugs. This leads to a hugely informative point. The more experience the male had being aggressive prior to castration, the more aggression continues afterward. In otherwise, the less his being aggressive in the future requires testosterone and the more it's a function of social learning.

The traditional hospital practice of excluding parents ignored the importance of attachment relationships as regulators of the child’s emotions, behaviour and physiology. The child’s biological status would be vastly different under the circumstances of parental presence or absence. Her neurochemical output, the electrical activity in her brain’s emotional centres, her heart rate, blood pressure and the serum levels of the various hormones related to stress would all vary significantly. Life is possible only within certain well-defined limits, internal or external. We can no more survive, say, high sugar levels in our bloodstream than we can withstand high levels of radiation emanating from a nuclear explosion. The role of self-regulation, whether emotional or physical, may be likened to that of a thermostat ensuring that the temperature in a home remains constant despite the extremes of weather conditions outside. When the environment becomes too cold, the heating system is switched on. If the air becomes overheated, the air conditioner begins to work. In the animal kingdom, self-regulation is illustrated by the capacity of the warm-blooded creature to exist in a broad range of environments. It can survive more extreme variations of hot and cold without either chilling or overheating than can a coldblooded species. The latter is restricted to a much narrower range of habitats because it does not have the capacity to self-regulate the internal environment. Children and infant animals have virtually no capacity for biological self-regulation; their internal biological states—heart rates, hormone levels, nervous system activity — depend completely on their relationships with caregiving grown-ups. Emotions such as love, fear or anger serve the needs of protecting the self while maintaining essential relationships with parents and other caregivers. Psychological stress is whatever threatens the young creature’s perception of a safe relationship with the adults, because any disruption in the relationship will cause turbulence in the internal milieu. Emotional and social relationships remain important biological influences beyond childhood. “Independent self-regulation may not exist even in adulthood,” Dr. Myron Hofer, then of the Departments of Psychiatry and Neuroscience at Albert Einstein College of Medicine in New York, wrote in 1984. “Social interactions may continue to play an important role in the everyday regulation of internal biologic systems throughout life.” Our biological response to environmental challenge is profoundly influenced by the context and by the set of relationships that connect us with other human beings. As one prominent researcher has expressed it most aptly, “Adaptation does not occur wholly within the individual.” Human beings as a species did not evolve as solitary creatures but as social animals whose survival was contingent on powerful emotional connections with family and tribe. Social and emotional connections are an integral part of our neurological and chemical makeup. We all know this from the daily experience of dramatic physiological shifts in our bodies as we interact with others. “You’ve burnt the toast again,” evokes markedly different bodily responses from us, depending on whether it is shouted in anger or said with a smile. When one considers our evolutionary history and the scientific evidence at hand, it is absurd even to imagine that health and disease could ever be understood in isolation from our psychoemotional networks. “The basic premise is that, like other social animals, human physiologic homeostasis and ultimate health status are influenced not only by the physical environment but also by the social environment.” From such a biopsychosocial perspective, individual biology, psychological functioning and interpersonal and social relationships work together, each influencing the other.