Henrietta Lacks Quotes

Like the Bible said,' Gary whispered, 'man brought nothing into this world and he'll carry nothing out. Sometimes we care about stuff too much. We worry when there's nothing to worry about.

She's the most important person in the world and her family living in poverty. If our mother is so important to science, why can't we get health insurance?

But I tell you one thing, I don't want to be immortal if it mean living forever, cause then everybody else just die and get old in front of you while you stay the same, and that's just sad.

Some things you got to release. Gary said. The more you hold them in, the worse you get. When you release them, they got to go somewhere else. The Bible says He can carry all that burden.

When he asked if she was okay, her eyes welled with tears and she said, “Like I’m always telling my brothers, if you gonna go into history, you can’t do it with a hate attitude. You got to remember, times was different.

I keep with me all I know about you deep in my soul, because I am part of you, and you are me.

Like I'm always telling my brothers, if you gonna go into history, you can't do it with a hate attitude. You got to remember, times was different.

We must not see any person as an abstraction. Instead, we must see in every person a universe with its own secrets, with its own treasures, with its own sources of anguish, and with some measure of triumph. —ELIE WIESEL from The Nazi Doctors and the Nuremberg Code

For me, it's writing a book and telling people about this story.

But today when people talk about the history of Hopkins’s relationship with the black community, the story many of them hold up as the worst offense is that of Henrietta Lacks—a black woman whose body, they say, was exploited by white scientists.

Only cells that had been transformed by a virus or a genetic mutation had the potential to become immortal.

Black scientists and technicians, many of them women, used cells from a black woman to help save the lives of millions of Americans, most of them white. And they did so on the same campus—and at the very same time—that state officials were conducting the infamous Tuskegee syphilis studies.

Henrietta’s were different: they reproduced an entire generation every twenty-four hours, and they never stopped. They became the first immortal human cells ever grown in a laboratory.

Henrietta’s cells have now been living outside her body far longer than they ever lived inside it,

if our mother cells done so much for medicine, how come her family can’t afford to see no doctors?

When I tell people the story of Henrietta Lacks and her cells, their first question is usually Wasn’t it illegal for doctors to take Henrietta’s cells without her knowledge? Don’t doctors have to tell you when they use your cells in research? The answer is no—not in 1951, and not in 2009, when this book went to press. Today

Whether you think the commercialization of medical research is good or bad depends on how into capitalism you are.

I’ve tried to imagine how she’d feel knowing that her cells went up in the first space missions to see what would happen to human cells in zero gravity, or that they helped with some of the most important advances in medicine: the polio vaccine, chemotherapy, cloning, gene mapping, in vitro fertilization. I’m pretty sure that she—like most of us—would be shocked to hear that there are trillions more of her cells growing in laboratories now than there ever were in her body.

If our mother so important to science, why can’t we get health insurance?

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and he petitioned the city of Atlanta to name October 11, the date of the conference, Henrietta Lacks Day. The city agreed and gave him an official proclamation from the mayor’s office.

if you gonna go into history, you can’t do it with a hate attitude. You got to remember, times was different.

But I always have thought it was strange, if our mother cells done so much for medicine, how come her family can’t afford to see no doctors?

That there’s Henrietta’s mother,” he said, pointing to a lone tombstone near the cemetery’s edge, surrounded by trees and wild roses. It was several feet tall, its front worn rough and browned from age and weather.

When it came to growing viruses—as with many other things—the fact that HeLa was malignant just made it more useful.

Lefkowitz wrote, “Every human being has an inalienable right to determine what shall be done with his own body.

angry—angry that Henrietta’s cells were being sold for twenty-five dollars a vial, and angry that articles

Though no law or code of ethics required doctors to ask permission before taking tissue from a living patient, the law made it very clear that performing an autopsy or removing tissue from the dead without permission was illegal.

Hopkins say they gave them cells away,” Lawrence yelled, “but they made millions! It’s not fair! She’s the most important person in the world and her family living in poverty. If our mother so important to science, why can’t we get health insurance?

HeLa was a workhorse: it was hardy, it was inexpensive, and it was everywhere. And

man brought nothing into this world and he’ll carry nothing out. Sometime we care about stuff too much. We worry when there’s nothing to worry about.

people

Like I’m always telling my brothers, if you gonna go into history, you can’t do it with a hate attitude. You got to remember, times was different.

She’s simply called HeLa, the code name given to the world’s first immortal human cells—her cells, cut from her cervix just months before she died.

Genetically speaking, humans are terrible research subjects. We’re genetically promiscuous—we mate with anyone we choose—and we don’t take kindly to scientists telling us who to reproduce with.

As one of Henrietta’s relatives said to me, “If you pretty up how people spoke and change the things they said, that’s dishonest. It’s taking away their lives, their experiences, and their selves.” In

He told them he was testing their immune systems; he said nothing about injecting them with someone else’s malignant cells.

Like many doctors of his era, TeLinde often used patients from the public wards for research, usually without their knowledge.

The Way of All Flesh

The fundamental problem here isn’t the money; it’s the notion that the people these tissues come from don’t matter.

one had multiple sclerosis and

She’s the most important person in the world and her family living in poverty. If our mother so important to science, why can’t we get health insurance?

Then he’d stand the bird upright, saying, “Sorry, old fella,” and put it back in its cage.

The Way of All Flesh,

restricting HeLa cell use would be disastrous. “The impact that would have on science is inconceivable,” he said.

She demanded to know if anyone ever tried to teach her sister sign language. No one had.

We must not see any person as an abstraction. Instead, we must see in every person a universe with its own secrets, with its own treasures, with its own sources of anguish, and with some measure of triumph. —ELIE WIESEL

The Geys were determined to grow the first immortal human cells: a continuously dividing line of cells all descended from one original sample, cells that would constantly replenish themselves and never die.

When you go to the doctor for a routine blood test or to have a mole removed, when you have an appendectomy, tonsillectomy, or any other kind of ectomy, the stuff you leave behind doesn’t always get thrown out. Doctors, hospitals, and laboratories keep it. Often indefinitely.

To discourage slaves from meeting or escaping, slave owners told tales of gruesome research done on black bodies, then covered themselves in white sheets and crept around at night, posing as spirits coming to infect black people with disease or steal them for research. Those sheets eventually gave rise to the white hooded cloaks of the Ku Klux Klan.

Day wouldn’t have understood the concept of immortal cells or HLA markers coming from anyone, accent or not—he’d only gone to school for four years of his life, and he’d never studied science. The only kind of cell he’d heard of was the kind Zakariyya was living in out at Hagerstown. So he did what he’d always done when he didn’t understand something a doctor said: he nodded and said yes.

an idea hit him, he sat wherever he was—at his desk, kitchen table, a bar, or behind the wheel of his car—gnawing on his ever-present cigar and scribbling diagrams on napkins or the backs of torn-off bottle labels.

When we are prevented from attempting seemingly innocuous studies of cancer behavior in humans … we may mark 1966 as the year in which all medical progress ceased.

1953 and moved into a house of his own—he had no idea what

Sometimes I wonder, if somebody taught her sign language, maybe she’d still be alive.

quoted a local woman, Courtney Speed, who owned a grocery

I was a kid who’d failed freshman year at the regular public high school because she never showed up.

And when the Lord chooses an angel to do his work, you never know what they going to come back looking like.

Baltimore, looking at a genetics textbook. Her

Many doctors tested drugs on slaves and operated on them to develop new surgical techniques, often without using anesthesia. Fear

The American Type Culture Collection—a nonprofit whose funds go mainly toward maintaining and providing pure cultures for science—has been selling HeLa since the sixties. When this book went to press, their price per vial was $256. The ATCC won’t reveal how much money it brings in from HeLa sales each year, but since HeLa is one of the most popular cell lines in the world, that number is surely significant.

Everyone in the audience knew what that meant. On top of saying they’d possibly wasted more than a decade and millions of research dollars, Gartler was also suggesting that spontaneous transformation—one of the most celebrated prospects for finding a cure for cancer—might not exist. Normal cells didn’t spontaneously become cancerous, he said; they were simply taken over by HeLa.

But I always have thought it was strange, if our mother cells done so much for medicine, how come her family can’t afford to see no doctors? Don’t make no sense. People got rich off my mother without us even knowin about them takin her cells, now we don’t get a dime.

Many scientists believed that since patients were treated for free in the public wards, it was fair to use them as research subjects as a form of payment. And as Howard Jones once wrote, “Hopkins, with its large indigent black population, had no dearth of clinical material.

Nelson-Rees had since been hired by the National Cancer Institute to help stop the contamination problem. He would become known as a vigilante who published “HeLa Hit Lists” in Science, listing any contaminated lines he found, along with the names of researchers who’d given him the cells. He didn’t warn researchers when he found that their cells had been contaminated with HeLa; he just published their names, the equivalent of having a scarlet H pasted on your lab door.

Genetically speaking, humans are terrible research subjects. We're genetically promiscuous--we mate with anyone we choose--and we don't take kindly to scientists telling us who we should reproduce with. Plus, unlike plans and mice, it takes decades to produce enough offspring to give scientists much meaningful data.

These cells have transformed modern medicine. … They shaped the policies of countries and of presidents. They even became involved in the Cold War. Because scientists were convinced that in her cells lay the secret of how to conquer death

HeLa cells were one of the most important things that happened to medicine in the last hundred years,” Defler said. Then, matter-of-factly, almost as an afterthought, he said, “She was a black woman.” He erased her name in one fast swipe and blew the chalk from his hands. Class was over.

A few minutes later, seemingly out of nowhere, he pointed to the dirt and said, “You know, white folks and black folks all buried over top of each other in here. I guess old white granddaddy and his brothers was buried in here too. Really no tellin who in this ground now.” Only thing he knew for sure, he said, was that there was something beautiful about the idea of slave-owning white Lackses being buried under their black kin. “They spending eternity in the same place,” he told me, laughing. “They must’ve worked out their problems by now!

I hereby give consent to the staff of The Johns Hopkins Hospital to perform any operative procedures and under any anaesthetic either local or general that they may deem necessary in the proper surgical care and treatment of:

today, around 90 percent of all sexually active adults become infected with at least one strain during their lifetimes.

Viruses reproduce by injecting bits of their genetic material into a living cell, essentially reprogramming the cell so it reproduces the virus instead of itself.

Reader's Digest ran articles by Corell advising women that a husband should not be induced by an oversexed wife to perform a sexual act.

He specified that the only patients to be charged were those who could easily afford it, and that any money they brought in should then be spent treating those without money.

Scientists had been trying to keep human cells alive in culture for decades, but they all eventually died. Henrietta’s were different: they reproduced an entire generation every twenty-four hours, and they never stopped. They became the first immortal human cells ever grown in a laboratory.

man brought nothing into this world and he’ll carry nothing out. Sometime we care about stuff too much. We worry when there’s nothing to worry about.” In a moment of clarity, Deborah nodded, saying, “And we bring our own body down by doing it.

A physician violates his duty to his patient and subjects himself to liability if he withholds any facts which are necessary to form the basis of an intelligent consent by the patient to the proposed treatment.” He wrote that there needed to be “full disclosure of facts necessary to an informed consent.

We must not see any person as an abstraction. Instead, we must see in every person a universe with its own secrets, with its own treasures, with its own sources of anguish, and with some measure of triumph.

HELA CELLS ARE GROWN Black scientists and technicians, many of them women, used cells from a black woman to help save the lives of millions of Americans, most of them white. And they did so on the same campus—and at the very same time—that state officials were conducting the infamous Tuskegee syphilis studies.

But more than anything, they worried that since everyone was using different media ingredients, recipes, cells, and techniques, and few knew their peers’ methods, it would be difficult, if not impossible, to replicate one another’s experiments. And replication is an essential part of science: a discovery isn’t considered valid if others can’t repeat the work and get the same result.

Ultimately the judge threw Moore’s suit out of court, saying he had no case. Ironically, in his decision, the judge cited the HeLa cell line as a precedent for what happened with the Mo cell line. The fact that no one had sued over the growth or ownership of the HeLa cell line, he said, illustrated that patients didn’t mind when doctors took their cells and turned them into commercial products. The judge believed Moore was unusual in his objections. But in fact, he was simply the first to realize there was something potentially objectionable going on.

Nearly seven years after Moore originally filed suit, the Supreme Court of California ruled against him in what became the definitive statement on this issue: When tissues are removed from your body, with or without your consent, any claim you might have had to owning them vanishes. When you leave tissues in a doctor’s office or a lab, you abandon them as waste, and anyone can take your garbage and sell it. Since Moore had abandoned his cells, they were no longer a product of his body, the ruling said. They had been “transformed” into an invention and were now the product of Golde’s “human ingenuity” and “inventive effort.

But normal human cells—either in culture or in the human body—can’t grow indefinitely like cancer cells. They divide only a finite number of times, then stop growing and begin to die. The number of times they can divide is a specific number called the Hayflick Limit, after Leonard Hayflick, who’d published a paper in 1961 showing that normal cells reach their limit when they’ve doubled about fifty times.

As a result of its investigation, the NIH said that to qualify for funding, all proposals for research on human subjects had to be approved by review boards—independent bodies made up of professionals and laypeople of diverse races, classes, and backgrounds—to ensure that they met the NIH’s ethics requirements, including detailed informed consent.

Because of patent licensing fees, it costs $25,000 for an academic institution to license the gene for researching a common blood disorder, hereditary haemochromatosis, and up to $250,000 to license the same gene for commercial testing. At that rate, it would cost anywhere from $46.4 million (for academic institutions) to $464 million (for commercial labs) to test one person for all known genetic diseases.

All cancers originate from a single cell gone wrong and are categorized based on the type of cell they start from. Most cervical cancers are carcinomas, which grow from the epithelial cells that cover the cervix and protect its surface.

like it or not, we live in a market-driven society, and science is part of that market.

The dead have no right to privacy–even if a part of them is still alive.

Lillian converted to Puerto Rican,” Gladys said, holding the letter to her chest. I looked at Gary, who sat beside her. “Lillian’s skin was real light, even lighter than mom’s,” Gary explained. “She married a Puerto Rican somewhere in New York. Since she could pass, she disowned her blackness—converted to Puerto Rican because she didn’t want to be black no more.

When I saw those toenails,” Mary told me years later, “I nearly fainted. I thought, Oh jeez, she’s a real person. I started imagining her sitting in her bathroom painting those toenails, and it hit me for the first time that those cells we’d been working with all this time and sending all over the world, they came from a live woman. I’d never thought of it that way.

And for several years the public has been sending samples by the millions to personalized DNA testing companies like 23andMe, which only provide customers with their personal medical or genealogical information if they first sign a form granting permission for their samples to be stored for future research.

As a result of its investigation, the NIH said that to qualify for funding, all proposals for research on human subjects had to be approved by review boards—independent bodies made up of professionals and laypeople of diverse races, classes, and backgrounds—to ensure that they met the NIH’s ethics requirements, including detailed informed consent. Scientists said medical research was doomed. In a letter to the editor of Science, one of them warned, “When we are prevented from attempting seemingly innocuous studies of cancer behavior in humans … we may mark 1966 as the year in which all medical progress ceased.

In recent years, using tissue samples from themselves, their families, and their patients, scientists had grown cells of all kinds—prostate cancer, appendix, foreskin, even bits of human cornea—often with surprising ease. Researchers were using that growing library of cells to make historic discoveries: that cigarettes caused lung cancer; how X-rays and certain chemicals

Some of the stories were conjured by white plantation owners taking advantage of the long-held African belief that ghosts caused disease and death. To discourage slaves from meeting or escaping, slave owners told tales of gruesome research done on black bodies, then covered themselves in white sheets and crept around at night, posing as spirits coming to infect black people with disease or steal them for research. Those sheets eventually gave rise to the white hooded cloaks of the Ku Klux Klan.

For Deborah and her family—and surely many others in the world—that answer was so much more concrete than the explanation offered by science: that the immortality of Henrietta’s cells had something to do with her telomeres and how HPV interacted with her DNA. The idea that God chose Henrietta as an angel who would be reborn as immortal cells made a lot more sense to them than the explanation

We must not see any person as an abstraction. Instead, we must see in every person a universe with its own secrets, with its own treasures, with its own sources of anguish, and with some measure of triumph. —ELIE WIESEL from The Nazi Doctors and the Nuremberg Code

Southam’s research was only one of hundreds of similarly unethical studies. Beecher published a detailed list of the twenty-two worst offenders, including researchers who’d injected children with hepatitis and others who’d poisoned patients under anesthesia using carbon dioxide. Southam’s study was included as example number 17. Despite scientists’ fears, the ethical crackdown didn’t slow scientific progress. In fact, research flourished. And much of it involved HeLa.

Because of this history, black residents near Hopkins have long believed the hospital was built in a poor black neighborhood for the benefit of scientists—to give them easy access to potential research subjects. In fact, it was built for the benefit of Baltimore’s poor.

In 1965 two British scientists, Henry Harris and John Watkins, took cell sex an important step further. They fused HeLa cells with mouse cells and created the first human-animal hybrids—cells that contained equal amounts of DNA from Henrietta and a mouse. By doing this, they helped make it possible to study what genes do, and how they work.

He thought she was sleeping, so he touched her arm, saying, “Dale, time to get up.” But she wasn’t sleeping. “She’s in a better place now,” Sonny told me. “A heart attack just after Mother’s Day—she wouldn’t have wanted it another way. She’s suffered a lot in life, and now she’s happy.

The Times of London called the HeLa-mouse cells the “strangest hybrid form of life ever seen in the lab—or out of it.” A Washington Post editorial said, “We cannot afford any artificially induced mouse-men.” It called the research “horrendous” and said the researchers should leave humans alone and “go back to their yeasts and fungi.” One article ran with an image of a half-human, half-mouse creature with a long, scaly tail; another ran with a cartoon of a hippopotamus-woman reading the newspaper at a bus stop.

In 1999 the RAND Corporation published a report (the first and, so far, last of its kind) with a “conservative estimate” that more than 307 million tissue samples from more than 178 million people were stored in the United States alone. This number, the report said, was increasing by more than 20 million samples each year. The samples come from routine medical procedures, tests, operations, clinical trials, and research donations. They sit in lab freezers, on shelves, or in industrial vats of liquid nitrogen. They’re stored at military facilities, the FBI, and the National Institutes of Health.

the negative press about Southam’s work had gotten the attention of the NIH, which funded his research and required its investigators to get consent for all studies involving humans. In response to the Southam situation, the NIH investigated all their grantee institutions and found that only nine out of fifty-two had any policy in place to protect the rights of research subjects.

Reader’s Digest ran articles by Carrel advising women that a “husband should not be induced by an oversexed wife to perform a sexual act,” since sex drained the mind. In his best-selling book, Man, the Unknown, he proposed fixing what he believed was “an error” in the U.S. Constitution that promised equality for all people. “The feebleminded and the man of genius should not be equal before the law,” he wrote. “The stupid, the unintelligent, those who are dispersed, incapable of attention, of effort, have no right to a higher education.

in immortality for the masses. He was a eugenicist: organ transplantation and life extension were ways to preserve what he saw as the superior white race, which he believed was being polluted by less intelligent and inferior stock, namely the poor, uneducated, and nonwhite. He dreamed of never-ending life for those he deemed worthy, and death or forced sterilization for everyone else. He’d later praise Hitler for the “energetic measures” he took in that direction.

Like many doctors of his era, TeLinde often used patients from the public wards for research, usually without their knowledge. Many scientists believed that since patients were treated for free in the public wards, it was fair to use them as research subjects as a form of payment. And as Howard Jones once wrote, "Hopkins, with its large indigent black population, had no dearth of clinical material

The tribunal set forth a ten-point code of ethics now known as the Nuremberg Code, which was to govern all human experimentation worldwide. The first line in that code says, “The voluntary consent of the human subject is absolutely essential.

There are more than one hundred strains of HPV in existence, thirteen of which cause cervical, anal, oral, and penile cancer—today, around 90 percent of all sexually active adults become infected with at least one strain during their lifetimes.

The term informed consent first appeared in court documents in 1957, in a civil court ruling on the case of a patient named Martin Salgo. He went under anesthesia for what he thought was a routine procedure and woke up permanently paralyzed from the waist down. The doctor hadn’t told him the procedure carried any risks at all. The

Soon after, Deborah asked Bobbette what pregnant was. Bobbette told her, then grabbed Deborah’s shoulders again and told her to listen good. “I know your mother and father and all the cousins all mingled together in their own way, but don’t you ever do it, Dale. Cousins are not supposed to be havin sex with each other. That’s uncalled for.

When Southam began injecting people with HeLa cells in 1954, there was no formal research oversight in the United States. Since the turn of the century, politicians had been introducing state and federal laws with hopes of regulating human experimentation, but physicians and researchers always protested. The bills were repeatedly voted down for fear of interfering with the progress of science, even though other countries—including, ironically, Prussia—had enacted regulations governing human research as early as 1891.

Soon after Harris’s HeLa-chicken study, a pair of researchers at New York University discovered that human-mouse hybrids lost their human chromosomes over time, leaving only the mouse chromosomes. This allowed scientists to begin mapping human genes to specific chromosomes by tracking the order in which genetic traits vanished. If a chromosome disappeared and production of a certain enzyme stopped, researchers knew the gene for that enzyme must be on the most recently vanished chromosome. Scientists in laboratories throughout North America and Europe began fusing cells and using them to map genetic traits to specific chromosomes, creating a precursor to the human genome map we have today.

Henrietta was a black woman born of slavery and sharecropping who fled north for prosperity, only to have her cells used as tools by white scientists without her consent. It was a story of white selling black, of black cultures “contaminating” white ones with a single cell in an era when a person with “one drop” of black blood had only recently gained the legal right to marry a white person. It was also the story of cells from an uncredited black woman becoming one of the most important tools in medicine. This was big news.

A book that I would recommend for everyone: The Immortal Life of Henrietta Lacks.

Henrietta died in 1951 from a vicious case of cervical cancer, he told us. But before she died, a surgeon took samples of her tumor and put them in a petri dish. Scientists had been trying to keep human cells alive in culture for decades, but they all eventually died. Henrietta’s were different: they reproduced an entire generation every twenty-four hours, and they never stopped. They became the first immortal human cells ever grown in a laboratory.

After years of disbelief and argument from other scientists, Hayflick’s paper on cell limits became one of the most widely cited in his field. It was an epiphany: scientists had been trying for decades to grow immortal cell lines using normal cells instead of malignant ones, but it had never worked. They thought their technique was the problem, when in fact it was simply that the lifespan of normal cells was preprogrammed. Only cells that had been transformed by a virus or a genetic mutation had the potential to become immortal. Scientists

And in the late nineties, two women sued Hopkins, claiming that its researchers had knowingly exposed their children to lead, and hadn’t promptly informed them when blood tests revealed that their children had elevated lead levels—even when one developed lead poisoning. The research was part of a study examining lead abatement methods, and all families involved were black. The researchers had treated several homes to varying degrees, then encouraged landlords to rent those homes to families with children so they could then monitor the children’s lead levels.

Sonny had a quintuple bypass in 2003, when he was fifty-six years old—the last thing he remembered before falling unconscious under the anesthesia was a doctor standing over him saying his mother’s cells were one of the most important things that had ever happened to medicine. Sonny woke up more than $125,000 in debt because he didn’t have health insurance to cover the surgery.

Sadie told me years later. “We couldn’t help it. They played music that when you heard it just put your soul into it. We’d two-step across that floor, jiggle to some blues, then somebody maybe put a quarter in there and play a slow music song, and Lord we’d just get out there and shake and turn around and all like that!” She giggled like a young girl. “It was some beautiful times.

Only cells that had been transformed by a virus or a genetic mutation had the potential to become immortal. Scientists knew from studying HeLa that cancer cells could divide indefinitely, and they’d speculated for years about whether cancer was caused by an error in the mechanism that made cells die when they reached their Hayflick Limit. They also knew that there was a string of DNA at the end of each chromosome called a telomere, which shortened a tiny bit each time a cell divided, like time ticking off a clock. As normal cells go through life, their telomeres shorten with each division until they’re almost gone. Then they stop dividing and begin to die. This process correlates with the age of a person: the older we are, the shorter our telomeres, and the fewer times our cells have left to divide before they die. By the early nineties, a scientist at Yale had used HeLa to discover that human cancer cells contain an enzyme called telomerase that rebuilds their telomeres. The presence of telomerase meant cells could keep regenerating their telomeres indefinitely.

I later learned that while Elsie was at Crownsville, scientists often conducted research on patients there without consent, including one study titled "Pneumoencephalographic and skull X-ray studies in 100 epileptics." Pneumoencephalography was a technique developed in 1919 for taking images of the brain, which floats in a sea of liquid. That fluid protects the brain from damage, but makes it very difficult to X-ray, since images taken through fluid are cloudy. Pneumoencephalography involved drilling holes into the skulls of research subjects, draining the fluid surrounding their brains, and pumping air or helium into the skull in place of the fluid to allow crisp X-rays of the brain through the skull. the side effects--crippling headaches, dizziness, seizures, vomiting--lasted until the body naturally refilled the skull with spinal fluid, which usually took two to three months. Because pneumoencephalography could cause permanent brain damage and paralysis, it was abandoned in the 1970s. "There is no evidence that the scientists who did research on patients at Crownsville got consent from either the patients of their parents. Bases on the number of patients listed in the pneumoencephalography studyand the years it was conducted, Lurz told me later, it most likely involved every epileptic child in the hospital including Elsie. The same is likely true of at lest on other study called "The Use of Deep Temporal Leads in the Study of Psychomotor Epilepsy," which involved inserting metal probes into patients' brains.

But when he instructed his staff to give the injections without telling patients they contained cancer cells, three young Jewish doctors refused, saying they wouldn’t conduct research on patients without their consent. All three knew about the research Nazis had done on Jewish prisoners. They also knew about the famous Nuremberg Trials.

Carrel was a mystic who believed in telepathy and clairvoyance, and thought it was possible for humans to live several centuries through the use of suspended animation. Eventually he turned his apartment into a chapel, began giving lectures on medical miracles, and told reporters he dreamed of moving to South America and becoming a dictator.

They also knew that there was a string of DNA at the end of each chromosome called a telomere, which shortened a tiny bit each time a cell divided, like time ticking off a clock. As normal cells go through life, their telomeres shorten with each division until they’re almost gone. Then they stop dividing and begin to die. This process correlates with the age of a person: the older we are, the shorter our telomeres, and the fewer times our cells have left to divide before they die. By the early nineties, a scientist at Yale had used HeLa to discover that human cancer cells contain an enzyme called telomerase that rebuilds their telomeres. The presence of telomerase meant cells could keep regenerating their telomeres indefinitely. This explained the mechanics of HeLa’s immortality: telomerase constantly rewound the ticking clock at the end of Henrietta’s chromosomes so they never grew old and never died.

The Lackses aren’t the only ones who heard from a young age that Hopkins and other hospitals abducted black people. Since at least the 1800s, black oral history has been filled with tales of “night doctors” who kidnapped black people for research. And there were disturbing truths behind those stories. Some of the stories were conjured by white plantation owners taking advantage of the long-held African belief that ghosts caused disease and death. To discourage slaves from meeting or escaping, slave owners told tales of gruesome research done on black bodies, then covered themselves in white sheets and crept around at night, posing as spirits coming to infect black people with disease or steal them for research. Those sheets eventually gave rise to the white hooded cloaks of the Ku Klux Klan.

Since the Common Rule says that research subjects must be allowed to withdraw from research at any time, these experts have told me that, in theory, the Lacks family might be able to withdraw HeLa cells from all research worldwide. And in fact, there are precedents for such a case, including one in which a woman successfully had her father’s DNA removed from a database in Iceland. Every researcher I’ve mentioned that idea to shudders at the thought of it.

But Carrel wasn’t interested in immortality for the masses. He was a eugenicist: organ transplantation and life extension were ways to preserve what he saw as the superior white race, which he believed was being polluted by less intelligent and inferior stock, namely the poor, uneducated, and nonwhite. He dreamed of never-ending life for those he deemed worthy, and death or forced sterilization for everyone else. He’d later praise Hitler for the “energetic measures” he took in that direction.

Her cells were part of research into the genes that cause cancer and those that suppress it; they helped develop drugs for treating herpes, leukemia, influenza, hemophilia, and Parkinson’s disease; and they’ve been used to study lactose digestion, sexually transmitted diseases, appendicitis, human longevity, mosquito mating, and the negative cellular effects of working in sewers.

I didn’t sign no papers,” he said. “I just told them they could do a topsy Nothin else. Them doctors never said nuthin about keepin her alive in no tubes or growin no cells. All they told me was they wanted to do a topsy see if they could help my children. And I’ve always just knowed this much: they is the doctor, and you got to go by what they say. I don’t know as much as they do. And them doctors said if I gave em my old lady, they could use her to study that cancer and maybe help my children, my grandchildren.

You got my wife cells?" "Yeah," I said thinking he was asking if I was calling about his wife's cells. "Yeah?" He said, suddenly bright, alert. "You got my wife cells? She know you talking?" "Yeah" I said thinking he was asking if Deborah knew I was calling. "Well, so let my old lady cells talk to you and leave me alone," he snapped. "I had enough 'a you people." Then he hung up .

So together, Reader and Vincent used HeLa cells as the springboard to launch the first industrial-scale, for-profit cell distribution center. It started with what Reader lovingly referred to as his Cell Factory. In Bethesda, Maryland, in the middle of a wide-open warehouse that was once a Fritos factory, he built a glass-enclosed, room that housed a rotating conveyor belt with hundreds of test-tube holders built into it. Outside the glass room, he had a setup much like the Tuskegee's, with massive vats of culture medium, only bigger. When cells were ready for shipping, he'd sound a loud bell and all the workers in the building, including mailroom clerks, would stop what they were doing, scrub themselves at the sterilization station, grab a cap and gown, and line up at the conveyor belt. Some filled tubes, others inserted rubber stoppers, sealed tubes, or stacked them inside a walk-in incubator where they stayed until being packaged for shipping.

the history of experimenting on black people does not hold a place in their referential memory.5 No one makes mention of Tuskegee’s syphilis experiments on black men, or the military experiments of mustard gas on black soldiers, among other nonwhites, or J. Marion Sims’s experimentation on black women.6 No mention of Henrietta Lacks. My historical memory starts tossing examples at me as if it’s having its own dinner party. In the real one, no one wonders what the parents of the black children think when they see the word “study” associated with the center.

Grandpa Tommy hitched the horses after supper and readied them to ride into the town of South Boston—home of the nation’s second-largest tobacco market, with tobacco parades, a Miss Tobacco pageant, and a port where boats collected the dried leaves for people around the world to smoke.

At that point, more than 15,000 women were dying each year from cervical cancer. The Pap smear had the potential to decrease that death rate by 70 percent or more, but there were two things standing in its way: first, many women - like Henrietta - simply didn't get the test; and, second, even when they did, few doctors knew how to interpret the results accurately, because they didn't know what various stages of cervical cancer looked like under a microscope. Some mistook cervical infections for cancer and removed a woman's entire reproductive tract when all she needed was antibiotics. Others mistook malignant changes for infection, sending women home with antibiotics only to have them return later, dying from metastasized cancer. And even when doctors correctly diagnosed precancerous changes, they often didn't know how those changes should be treated.

Soon after Elsie’s death, a new warden took over at Crownsville and began releasing hundreds of patients who’d been institutionalized unnecessarily. The Washington Post article quoted him saying, “The worst thing you can do to a sick person is close the door and forget about him.” When I read that line out loud, Deborah whispered, “We didn’t forget about her. My mother died … nobody told me she was here. I would have got her out.

Mary stood beside Wilbur, waiting as he sewed Henrietta’s abdomen closed. She wanted to run out of the morgue and back to the lab, but instead, she stared at Henrietta’s arms and legs—anything to avoid looking into her lifeless eyes. Then Mary’s gaze fell on Henrietta’s feet, and she gasped: Henrietta’s toenails were covered in chipped bright red polish. “When I saw those toenails,” Mary told me years later, “I nearly fainted. I thought, Oh jeez, she’s a real person. I started imagining her sitting in her bathroom painting those toenails, and it hit me for the first time that those cells we’d been working with all this time and sending all over the world, they came from a live woman. I’d never thought of it that way.”      

I later learned that while Elsie was at Crownsville, scientists often conducted research on patients there without consent, including one study titled “Pneumoencephalographic and skull X-ray studies in 100 epileptics.” Pneumoencephalography was a technique developed in 1919 for taking images of the brain, which floats in a sea of fluid. That fluid protects the brain from damage, but makes it very difficult to X-ray, since images taken through fluid are cloudy. Pneumoencephalography involved drilling holes into the skulls of research subjects, draining the fluid surrounding their brains, and pumping air or helium into the skull in place of the fluid to allow crisp X-rays of the brain through the skull. The side effects—crippling headaches, dizziness, seizures, vomiting—lasted until the body naturally refilled the skull with spinal fluid, which usually took two to three months. Because pneumoencephalography could cause permanent brain damage and paralysis, it was abandoned in the 1970s. There

Hopkins was one of the top hospitals in the country. It was built in 1889 as a charity hospital for the sick and poor, and it covered more than a dozen acres where a cemetery and insane asylum once sat in East Baltimore. The public wards at Hopkins were filled with patients, most of them black and unable to pay their medical bills. David drove Henrietta nearly twenty miles to get there, not because they preferred it, but because it was the only major hospital for miles that treated black patients. This was the era of Jim Crow—when black people showed up at white-only hospitals, the staff was likely to send them away, even if it meant they might die in the parking lot. Even Hopkins, which did treat black patients, segregated them in colored wards, and had colored-only fountains. So when the nurse called Henrietta from the waiting room, she led her through a single door to a colored-only exam room—one in a long row of rooms divided by clear glass walls that let nurses see from one to the next.

In culture, cancer cells can go on dividing indefinitely, if they have a continual supply of nutrients, and thus are said to be “immortal.” A striking example is a cell line that has been reproducing in culture since 1951. (Cells of this line are called HeLa cells because their original source was a tumor removed from a woman named Henrietta Lacks.)

As a result of its investigation, the NIH said that to qualify for funding, all proposals for research on human subjects had to be approved by review boards—independent bodies made up of professionals and laypeople of diverse races, classes, and backgrounds—to ensure that they met the NIH’s ethics requirements, including detailed informed consent. Scientists said medical research was doomed. In a letter to the editor of Science, one of them warned, “When we are prevented from attempting seemingly innocuous studies of cancer behavior in humans … we may mark 1966 as the year in which all medical progress ceased.” Later that year, a Harvard anesthesiologist named Henry Beecher published a study in the New England Journal of Medicine showing that Southam’s research was only one of hundreds of similarly unethical studies. Beecher published a detailed list of the twenty-two worst offenders, including researchers who’d injected children with hepatitis and others who’d poisoned patients under anesthesia using carbon dioxide. Southam’s study was included as example number 17. Despite scientists’ fears, the ethical crackdown didn’t slow scientific progress. In fact, research flourished. And much of it involved HeLa. 18

Myriad Genetics, which holds the patents on the BRCA1 and BRCA2 genes responsible for most cases of hereditary breast and ovarian cancer, charges $3,000 to test for the genes. Myriad has been accused of creating a monopoly, since no one else can offer the test, and researchers can’t develop cheaper tests or new therapies without getting permission from Myriad and paying steep licensing fees. Scientists who’ve gone ahead with research involving the breast-cancer genes without Myriad’s permission have found themselves on the receiving end of cease-and-desist letters and threats of litigation. In May 2009 the American Civil Liberties Union, several breast-cancer survivors, and professional groups representing more than 150,000 scientists sued Myriad Genetics over its breast-cancer gene patents. Among other things, scientists involved in the case claim that the practice of gene patenting has inhibited their research, and they aim to stop it. The presence of so many scientists in the suit, many of them from top institutions, challenges the standard argument that ruling against biological patents would interfere with scientific progress

It seems to me the simplest explanation,” he told the audience, “is that they are all HeLa cell contaminants.” Scientists knew they had to keep their cultures free from bacterial and viral contamination, and they knew it was possible for cells to contaminate one another if they got mixed up in culture. But when it came to HeLa, they had no idea what they were up against. It turned out Henrietta’s cells could float through the air on dust particles. They could travel from one culture to the next on unwashed hands or used pipettes; they could ride from lab to lab on researchers’ coats and shoes, or through ventilation systems. And they were strong: if just one HeLa cell landed in a culture dish, it took over, consuming all the media and filling all the space.

But the history of Hopkins Hospital certainly isn’t pristine when it comes to black patients. In 1969, a Hopkins researcher used blood samples from more than 7,000 neighborhood children—most of them from poor black families—to look for a genetic predisposition to criminal behavior. The researcher didn’t get consent. The American Civil Liberties Union filed suit claiming the study violated the boys’ civil rights and breached confidentiality of doctor-patient relationships by releasing results to state and juvenile courts. The study was halted, then resumed a few months later using consent forms. And in the late nineties, two women sued Hopkins, claiming that its researchers had knowingly exposed their children to lead, and hadn’t promptly informed them when blood tests revealed that their children had elevated lead levels—even when one developed lead poisoning. The research was part of a study examining lead abatement methods, and all families involved were black. The researchers had treated several homes to varying degrees, then encouraged landlords to rent those homes to families with children so they could then monitor the children’s lead levels. Initially, the case was dismissed. On appeal, one judge compared the study to Southam’s HeLa injections, the Tuskegee study, and Nazi research, and the case eventually settled out of court. The Department of Health and Human Services launched an investigation and concluded that the study’s consent forms “failed to provide an adequate description” of the different levels of lead abatement in the homes.

I know my life could be better and I wish it was,” she told me. “When people hear about my mother cells they always say, ‘Oh y’all could be rich! Y’all gotta sue John Hopkin, y’all gotta do this and that.’ But I don’t want that.” She laughed. “Truth be told, I can’t get mad at science, because it help people live, and I’d be a mess without it. I’m a walking drugstore! I can’t say nuthin bad about science, but I won’t lie, I would like some health insurance so I don’t got to pay all that money every month for drugs my mother cells probably helped make.

If tissue samples--including blood cells--became patients' property, researchers taking them without consent and property rights up front would risk being charged with theft. The press ran story after story quoting lawyers and scientists saying that a victory for Moore would "create chaos for researcher" and [sound] the death knell to the university physician-scientist." They called it "a threat to the sharing of tissue for research purposes," and worried that patients would block the progress of science by holding out for excessive profits, even with cells that aren't worth, millions like Moore's.

Under the microscope, a cell looks a lot like a fried egg: It has a white (the cytoplasm) that’s full of water and proteins to keep it fed, and a yolk (the nucleus) that holds all the genetic information that makes you you. The cytoplasm buzzes like a New York City street. It’s crammed full of molecules and vessels endlessly shuttling enzymes and sugars from one part of the cell to another, pumping water, nutrients, and oxygen in and out of the cell. All the while, little cytoplasmic factories work 24/7, cranking out sugars, fats, proteins, and energy to keep the whole thing running and feed the nucleus—the brains of the operation. Inside every nucleus within each cell in your body, there’s an identical copy of your entire genome. That genome tells cells when to grow and divide and makes sure they do their jobs, whether that’s controlling your heartbeat or helping your brain understand the

When we do disability justice work, it becomes impossible to look at disability and not examine how colonialism created it. It becomes a priority to look at Indigenous ways of perceiving and understanding disability, for example. It becomes a space where we see that disability is all up in Black and brown/queer and trans communities—from Henrietta Lacks to Harriet Tubman, from the Black Panther Party’s active support for disabled organizers’ two-month occupation of the Department of Vocational Rehabilitation to force the passage of Section 504, the law mandating disabled access to public spaces and transportation to the chronic illness and disability stories of second-wave queer feminists of color like Sylvia Rivera, June Jordan, Gloria Anzaldúa, Audre Lorde, Marsha P. Johnson, and Barbara Cameron, whose lives are marked by bodily difference, trauma-surviving brilliance, and chronic illness but who mostly never used the term “disabled” to refer to themselves.

It cannot be denied that in cases of child rape the question of consent cannot arise at all, simply because a child or worst still an infant lacks mental power or knowledge to provide “consent” or even lacks physical ability to restrain. Moreover such an act subjects the child/infant to physical trauma, leading to even physical , mental and psychological ailment. To eliminate the horror from the face of the earth, I firmly believe we need to accept capital punishment as an apt punishment for subjecting a child to such a ordeal

It cannot be denied that in cases of child rape the question of consent cannot arise at all, simply because a child or worst still an infant lacks mental power or knowledge to provide "consent" or even lacks physical ability to restrain. Moreover such an act subjects the child/infant to physical trauma, leading to even physical, mental, and psychological ailment. To eliminate the horror from the face of the Earth, I firmly believe we need to accept capital punishment as an apt punishment for subjecting a child to such an ordeal.

Non ci sono testimonianze scritte del fatto che George Gey abbia visitato Henrietta in ospedale o le abbia fatto sapere in qualche modo cosa fosse successo alle sue cellule. E tutti i protagonisti della vicenda che ho intervistato sostengono che i due non si sono mai incontrati. O meglio, quasi tutti tranne Laure Aurelian, una microbiologa che lavorava con Gey al Johns Hopkins: "Non potrò mai dimenticarlo" mi disse. "George mi raccontò che si era avvicinato al letto di Henrietta e le aveva sussurrato: "Le tue cellule ti renderanno immortale". Le spiegò che quel campione avrebbe salvato innumerevoli vite. Lei sorrise. E gli disse che era felice di sapere che tutto quel dolore sarebbe servito a qualcosa".

like Devotion and The Immortal Life of Henrietta Lacks.

George Gey paid his way through a biology degree at the University of Pittsburgh by working as a carpenter and mason, and he could make nearly anything for cheap or free. During his second year in medical school, he rigged a microscope with a time-lapse motion picture camera to capture live cells on film. It was a Frankensteinish mishmash of microscope parts, glass, and 16-millimeter camera equipment from who knows where, plus metal scraps, and an old motor from Shapiro’s junkyard. He built it in a hole he’d blasted in the foundation of Hopkins, right below the morgue, its base entirely underground and surrounded by a thick wall of cork to keep it from jiggling when streetcars passed. At night, a Lithuanian lab assistant slept next to the camera on a cot, listening to its constant tick, making sure it stayed stable through the night, waking every hour to refocus it. With that camera, Gey and his mentor, Warren Lewis, filmed the growth of cells, a process so slow - like the growth of a flower - the naked eye couldn’t see it. They played the film at high speed so they could watch cell division on the screen in one smooth motion, like a story unfolding in a flip book.

Precipitous decisions by companies pertaining to employees, devoid of documented established ground of denial of any of the demands or rights sought by the employees, or as adumbrated in law, would be construed in all probability unpalatable by the labor department and Judiciary.

I believe you owe her Grace an apology, Tallant?" "What?" "Forgive me," the duke continued, "perhaps in all the excitement of the last few minutes my hearing became defective. I thought I heard you publicly declare that my wife is not a lady." Sir Peter's jaw dropped. "Those were not quite my words," he said, "but we all know that Henrietta is not exactly everyone's ideal image of a lady of quality." "She is mine," Eversleigh replied softly. Henry stole a startled look at his hard profile. She could hardly believe her ears. All her life she had been labeled a tomboy. Her family had always lamented, if in a loving way, her lack of feminine charms. Could the very correct and sophisticated Duke of Eversleigh be seriously claiming that she was his ideal lady?

Good one! Either hire the right person for the job and use their services or hire anyone and train them to do your bidding and that may not necessarily be the right one or the smart one. Bureaucratic-automated work culture festers poor leadership that exhibits the lack of routed efforts towards identifying the right person for the right job through the myriad nuances and subtleties of employee profiles/candidature, resulting in a manifest crack in organizational competence and dislodges itself from organizational goals.

Either hire the right person for the job and use their services or hire anyone and train them to do your bidding and that may not necessarily be the right move or the smart move. Bureaucratic-automated work culture festers poor leadership that exhibits the lack of routed efforts towards identifying the right person for the right job through the myriad nuances and subtleties of employee profiles/candidature, resulting in a manifest crack in organizational competence and dislodges itself from organizational goals.

Many organizations, oblivious that good work culture has the propensity to propel the organization to the next well, turn deaf ears and blind eyes to the cold culture that has inevitably developed within the structure due to lack of supervision and timely strategic advice and training. The higher management may view the work culture that has developed within the company as ancillary to business progress and lunge it across to the HR department to magically iron the creases of an involuntarily besmirched work culture or blunt work culture.

Many organizations, oblivious that good work culture has the propensity to propel the organization to the next level, turn deaf ears and blind eyes to the cold culture that has inevitably developed within the structure due to lack of supervision and timely strategic advice and training. The higher management may view the work culture that has developed within the company as ancillary to business progress and lunge it across to the HR department to magically iron the creases of an involuntarily besmirched work culture or blunt work culture.

HeLa cells,” Borger said. “That’s right,” Lawton nodded. “The HeLa cells are named after a woman named Henrietta Lacks. She died of cancer but not before her doctor took a biopsy from her cancerous tumor. It turned out to be one of the most surprising discoveries in the field of cytology. The cells from her tumor simply won’t die.

Henrietta Swan Leavitt worked as a human "computer" in the late 1800s. Her job was to count stars at the Harvard College Observatory, which had taken on the ambitious task of cataloging every star in the sky. The work demanded painstaking manual inspection of photographic plates to pin down the stars' position, color, and brightness. Edward Pickering, the director of the observatory, recruited men to do the job, only to be frustrated by their "lack of concentration and failure to pay attention to detail." Convinced that women could do a better job, he fired the men and hired a team of women, who were nicknamed "Pickering's Harem." Not only did Pickering get a more diligent team of workers, he paid them only about half as much as he paid the men. And he did not have to worry about the women wanting to make their own observations, for (as at Mount Wilson) they were not allowed to use the telescopes. It was as part of this team of desk-bound computers that Leavitt discovered something extraordinary.

It was a relief to believe that she was as she seemed, but the more he liked her, the less fair it seemed that she was being fooled. And Hugh wasn't such an ogre that he didn't care for her feelings. On the contrary, he was coming to like her very much. Unlike many society girls, Eliza didn't act as if any gentleman nearby was obliged to amuse her. She expressed such delight in a simple posy, he couldn't help wondering what she would say if he presented her with a real gift. She seemed utterly content to spend time in her garden with her dog, and didn't even evince the slightest boredom at living in Greenwich away from the whirl of society. He told himself it must be easy, with Cross's vast fortune at her disposal; she needn't fret about a dark and drab drawing room, as Edith did, or moan about her lack of new gowns, as Henrietta did. But somehow he knew it wasn't just the money. Eliza wasn't the type to complain. Instead she gave every appearance of being content with her life and taking joy in small pleasures.

Henrietta’s were different: they reproduced an entire generation every twenty-four hours