“
Jack...why is there a dragon in our backyard?
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Kyoko M. (Of Dawn & Embers (Of Cinder & Bone, #3))
“
A child from a parent who self-fertilized would be like a clone of the parent with severe genetic damage.
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Randall Munroe (What If?: Serious Scientific Answers to Absurd Hypothetical Questions)
“
Clones: Why should you take the blame for your mistakes when there’s a genetic replica of yourself that’d make a perfectly good scapegoat?
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Jarod Kintz (A Zebra is the Piano of the Animal Kingdom)
“
Every generation of cancer cells creates a small number of cells that is genetically different from its parents. When a chemotherapeutic drug or the immune system attacks cancer, mutant clones that can resist the attack grow out.
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Siddhartha Mukherjee (The Emperor of All Maladies: A Biography of Cancer)
“
I’m one of twenty-three orphan prodigies. We were created using genetic engineering technologies that have been suppressed from the mainstream. I’m at least half a century ahead of our times in terms of official science. The embryologists who created me selected the strongest genes from about a thousand sperm donors then used in-vitro fertilization to impregnate my mother and other women.
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James Morcan (The Ninth Orphan (The Orphan Trilogy, #1))
“
Every generation of cancer cells creates a small number of cells that is genetically different from its parents. When a chemotherapeutic drug or the immune system attacks cancer, mutant clones that can resist the attack grow out. The fittest cancer cell survives.
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Siddhartha Mukherjee (The Emperor of All Maladies: A Biography of Cancer)
“
Sturtevant’s rudimentary genetic map would foreshadow the vast and elaborate efforts to map genes along the human genome in the 1990s. By using linkage to establish the relative positions of genes on chromosomes, Sturtevant would also lay the groundwork for the future cloning of genes tied to complex familial diseases, such as breast cancer, schizophrenia, and Alzheimer’s disease. In about twelve hours, in an undergraduate dorm room in New York, he had poured the foundation for the Human Genome Project.
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Siddhartha Mukherjee (The Gene: An Intimate History)
“
I’d rather be me being me than me trying to be my own clone. I try to stay true to who I am as a person, not a genetically modified being.
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Jarod Kintz (The Days of Yay are Here! Wake Me Up When They're Over.)
“
Thus, the distinction between “natural” and “unnatural” has been obscured. Red grapefruits created by neutron radiation, seedless watermelons produced with the chemical compound colchicine, apple orchards in which every tree is a perfect genetic clone of its neighbors—none of these aspects of modern agriculture is natural. Yet most of us eat these foods without complaint.
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Jennifer A. Doudna (A Crack In Creation: Gene Editing and the Unthinkable Power to Control Evolution)
“
child from a parent who self-fertilized would be like a clone of the parent with severe genetic damage. The parent would have all the genes the child would, but the child wouldn’t have all the genes
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Randall Munroe (What If?: Serious Scientific Answers to Absurd Hypothetical Questions)
“
When scientists underestimate complexity, they fall prey to the perils of unintended consequences. The parables of such scientific overreach are well-known: foreign animals, introduced to control pests, become pests in their own right; the raising of smokestacks, meant to alleviate urban pollution, releases particulate effluents higher in the air and exacerbates pollution; stimulating blood formation, meant to prevent heart attacks, thickens the blood and results in an increased risk of blood clots in the heart.
But when nonscientists overestimate [italicized, sic] complexity- 'No one can possibly crack this [italicized, sic] code" - they fall into the trap of unanticipated consequences. In the early 1950s , a common trope among some biologists was that the genetic code would be so context dependent- so utterly determined by a particular cell in a particular organism and so horribly convoluted- that deciphering it would be impossible. The truth turned out to be quite the opposite: just one molecule carries the code, and just one code pervades the biological world. If we know the code, we can intentionally alter it in organisms, and ultimately in humans. Similarly, in the 1960s, many doubted that gene-cloning technologies could so easily shuttle genes between species. by 1980, making a mammalian protein in a bacterial cell, or a bacterial protein in a mammalian cell, was not just feasible, it was in Berg's words, rather "ridiculously simple." Species were specious. "Being natural" was often "just a pose.
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Siddhartha Mukherjee (The Gene: An Intimate History)
“
Vaccinations are the application of evolutionary principles in action. If we can control the contact made between pathogen and lymphocyte populations, we can go a long way toward eliminating disease.108 It doesn’t require total annihilation but rather a control on population dynamics. Vaccines are the way we use selective cloning to keep a pathogenic population in a state of benign coexistence. The process is based on evolution, as pointed out by Nobel laureate Susumu Tonegawa: “Genes can mutate and recombine. These dynamic characteristics of genetic material are essential elements of evolution. Do they also play an important role during the development of a single multicellular organism? Our results strongly suggest that this is the case for the immune system.
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Greg Graffin (Population Wars: A New Perspective on Competition and Coexistence)
“
The Pyrenean ibex, an extinct form of wild mountain goat, was brought back to life in 2009 through cloning of dna taken from skin samples. This was followed in June of 2010 by researchers at Jeju National University in Korea cloning a bull that had been dead for two years. Cloning methods are also being studied for use in bringing back Tasmanian tigers, woolly mammoths, and other extinct creatures, and in the March/April 2010 edition of the respected Archaeology magazine, a feature article by Zah Zorich (“Should We Clone Neanderthals?”) called for the resurrection via cloning of what some consider to be man’s closest extinct relative, the Neanderthals. National Geographic confirmed this possibility in its May 2009 special report, “Recipe for a Resurrection,” quoting Hendrik Poinar of McMaster University, an authority on ancient dna who served as a scientific consultant for the movie Jurassic Park, saying: “I laughed when Steven Spielberg said that cloning extinct animals was inevitable. But I’m not laughing anymore.… This is going to happen.
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Thomas Horn (Forbidden Gates: How Genetics, Robotics, Artificial Intelligence, Synthetic Biology, Nanotechnology, and Human Enhancement Herald The Dawn Of TechnoDimensional Spiritual Warfare)
“
Elms are dying all over the place, it's Dutch elm disease. [...] It came from America on a load of logs, and it's a fungal disease. That makes it sound even more as if it might be possible to do something. The elms are all one elm, they are clones, that's why they are all succumbing. No natural resistance among the population, because no variation. Twins are clones, too. If you looked at an elm tree you'd never think it was part of all the others. You'd see an elm tree. Same when people look at me now: they see a person, not half a set of twins.
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Jo Walton (Among Others)
“
In 2002 scientists demonstrated beautifully just how random the process of X inactivation really is, by cloning a calico cat. They took cells from an adult female cat, and carried out the standard (but still fiendishly tricky) process of cloning. To do this, they removed the nucleus from the adult cat cell and put it into a cat egg whose own chromosomes they’d removed. This egg was implanted into a surrogate cat mother, and a lively and beautiful female kitten was born. And she didn’t look anything like the genetically identical cat of which she was a clone.18
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Nessa Carey (Junk DNA: A Journey Through the Dark Matter of the Genome)
“
My view is that diversity is the breath of life, and we must not abandon that for any single form which happens to catch our fancy – even our genetic fancy. Cloning is the stabilisation of one form, and that runs against the whole current of creation – of human creation above all. Evolution is founded in variety and creates diversity; and of all animals, man is most creative because he carries and expresses the largest store of variety. Every attempt to make us uniform, biologically, emotionally, or intellectually, is a betrayal of the evolutionary thrust that has made man its apex. Yet
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Jacob Bronowski (The Ascent Of Man)
“
Huxley’s Brave New World is set in an indefinitely distant future: it will not be possible for many years to say that Huxley’s apprehensions have not proved justified. It is unlikely that populations will undergo genetic and environmental manipulation in the exact way that Huxley foresaw: there will never be a fixed number of predetermined strata, from Alpha Plus to Epsilon Minus Semi-Morons. But as an Italian scientist prepares to clone humans, and as reproduction grows as divorced from sex as sex is from reproduction, it is increasingly hard to regard Huxley’s vision as entirely far-fetched.
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Theodore Dalrymple (Our Culture, What's Left Of It)
“
bacterium. The fungus spreads the strands of its body over the ground and provides a welcoming bed. The alga or bacterium nestles inside these strands and uses the sun’s energy to assemble sugar and other nutritious molecules. As in any marriage, both partners are changed by their union. The fungus body spreads out, turning itself into a structure similar to a tree leaf: a protective upper crust, a layer for the light-capturing algae, and tiny pores for breathing. The algal partner loses its cell wall, surrenders protection to the fungus, and gives up sexual activities in favor of faster but less genetically exciting self-cloning.
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David George Haskell (The Forest Unseen: A Year's Watch in Nature)
“
Life, a miracle of nature,
an evolved molecule of matter,
blossomed in the vast expanse of oceans.
Methane, ammonia, hydrogen and water vapor
When joined under the radio-active sun,
The molecules of non living matter underwent
massive changes and became live.
It's this accident that made the molecule of protein,
Which even Stanley Miller reproduced in lab.
Evolution went on, and on and changed ,
from amoeba to dinosaurs, from ape to man,
It was an amazing architecture of nature ,
Which still continue improving human brain.
The amazing creation nature, the man,
kept on exploring the mysteries of nature,
and succeeded in duplicating nature's marvel
through his latest invention - the cloning,
and succeeded in decoding even the genetic code.
Still we have to salute the mother nature,
which has many more mysteries in store!.
”
”
V.A. Menon
“
Jack coughed slightly and offered his hand. “Hi, uh. I’m Jack.”
Kim took it. “Jack what?”
“Huh?”
“Your last name, silly.”
“Jackson.”
She blinked at him. “Your name is Jack Jackson?”
He blushed. “No, uh, my first name’s Rhett, but I hate it, so…”
He gestured to the chair and she sat. Her dress rode up several inches, exposing pleasing long lines of creamy skin. “Well, Jack, what’s your field of study?”
“Biological Engineering, Genetics, and Microbiology. Post-doc. I’m working on a research project at the institute.”
“Really? Oh, uh, my apple martini’s getting a little low.”
“I’ve got that, one second.” He scurried to the bar and bought her a fresh one. She sipped and managed to make it look not only seductive but graceful as well.
“What do you want to do after you’re done with the project?” Kim continued.
“Depends on what I find.”
She sent him a simmering smile. “What are you looking for?”
Immediately, Jack’s eyes lit up and his posture straightened. “I started the project with the intention of learning how to increase the reproduction of certain endangered species. I had interest in the idea of cloning, but it proved too difficult based on the research I compiled, so I went into animal genetics and cellular biology. It turns out the animals with the best potential to combine genes were reptiles because their ability to lay eggs was a smoother transition into combining the cells to create a new species, or one with a similar ancestry that could hopefully lead to rebuilding extinct animals via surrogate birth or in-vitro fertilization. We’re on the edge of breaking that code, and if we do, it would mean that we could engineer all kinds of life and reverse what damage we’ve done to the planet’s ecosystem.”
Kim stared. “Right. Would you excuse me for a second?”
She wiggled off back to her pack of friends by the bar. Judging by the sniggering and the disgusted glances he was getting, she wasn’t coming back.
Jack sighed and finished off his beer, massaging his forehead. “Yes, brilliant move. You blinded her with science. Genius, Jack.”
He ordered a second one and finished it before he felt smallish hands on his shoulders and a pair of soft lips on his cheek. He turned to find Kamala had returned, her smile unnaturally bright in the black lights glowing over the room. “So…how did it go with Kim?”
He shot her a flat look. “You notice the chair is empty.”
Kamala groaned. “You talked about the research project, didn’t you?”
“No!” She glared at him.
“…maybe…”
“You’re so useless, Jack.” She paused and then tousled his hair a bit. “Cheer up. The night’s still young. I’m not giving up on you.”
He smiled in spite of himself. “Yet.”
Her brown eyes flashed. “Never.
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Kyoko M. (Of Cinder and Bone (Of Cinder and Bone, #1))
“
Where people are striving, busy and stressed, emotions are denied or derided. The head and heart then separate, and this allows people and governments to act with great cruelty, resulting in violence, abuse and war. Today, in striving discontent, we move the world forward with science and technology, but rape the Earth of minerals and oil and are careless of pollution. Where there is no reverence for nature, there is a feeling of separation from it, which makes people feel they have the right to change it, genetically modify it, clone it or damage it by chopping down its forests and polluting its rivers. Disconnection from the heart, and its consequences of cruelty, slavery and injustice, also took place when Atlantis devolved, but even in their most dire times they rejected the idea of using fossil fuel because of the damage it would cause to the planet. However, in the darkest days they did clone, genetically modify, and implant people and plants. Right-brain societies are inevitably child centred, for children are considered to be a gift to the community. In Atlantis, the little ones were loved, honoured and included, even in elementary decision making. It was considered to be a collective responsibility to pass on the traditions and wisdom to the next generation, for they had no individual wealth to leave as a legacy. EXERCISE:
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Diana Cooper (Discover Atlantis)
“
Working independently, Baltimore and Temin discovered an enzyme found in retroviruses that could build DNA from an RNA template. They called the enzyme reverse transcriptase-"reverse" because it inverted the normal direction of information flow: from RNA back to DNA, or from a gene's message backward to a gene, thereby violating Crick's "central dogma" (that genetic information only moved from genes to messages, but never backward).
Using reverse transcriptase, ever RNA in a cell could be used as a template to build its corresponding gene. A biologist could thus generate a catalog, or "library" of all "active" genes in a cell-akin to a library of books grouped by subject. There would be a library of genes for T cells and another for red blood cells, a library for neurons in the retina, for insulin-secreting cells of the pancreas, and so forth. By comparing libraries derived from two cells-a T cell and a pancreas cell, say-an immunologist could fish out genes that were active in one cell and not the other (e.g., insulin or the T cell receptor). Once identified, that gene could be amplified a millionfold in bacteria. The gene could be isolated and sequenced, its RNA and protein sequence determined, its regulatory regions identified; it could be mutated an inserted into a different cell to decipher the gene's structure and function. In 1984 this technique was deployed to clone the T cell receptor-a landmark achievement in immunology.
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Siddhartha Mukherjee (The Gene: An Intimate History)
“
The triumph of the transsexual and of transvestitism casts a strange light, retrospectively, upon the sexual liberation espoused by an earlier generation. It now appears that this liberation - which, according to its own discourse, meant the bursting forth of the body's full erotic force, a process especially favorable to the principles of femininity and of sexual pleasure - may actually have been no more than an intermediate phase on the way to the confusion of categories that we have been discussing. The sexual revolution may thus turn out to have been just a stage in the genesis of transsexuality. What is at issue here, fundamentally, is the problematic fate of all revolutions.
The cybernetic revolution, in view of the equivalence of brain and computer, places humanity before the crucial question 'Am I a man or a machine? ' The genetic revolution that is taking place at the moment raises the question 'Am I a man or just a potential clone? ' The sexual revolution, by liberating all the potentialities of desire, raises another fundamental question, 'Am I a man or a woman?' (If it has done nothing else, psychoanalysis has certainly added its weight to this principle of sexual uncertainty.) As for the political and social revolution, the prototype for all the others, it will turn out to have led man by an implacable logic - having offered him his own freedom, his own free will - to ask himself where his own will lies, what he wants in his heart of hearts, and what he is entitled to expect from himself. To these questions there are no answers. Such is the paradoxical outcome of every revolution: revolution opens the door to indeterminacy, anxiety and confusion. Once the orgy was over, liberation was seen to have left everyone looking for their generic and sexual identity - and with fewer and fewer answers available, in view of the traffic in signs and the multiplicity of pleasures on offer. That is how we became transsexuals - just as we became transpoliticals: in other words, politically indifferent and undifferentiated beings, androgynous and hermaphroditic - for by this time we had embraced, digested and rejected the most contradictory ideologies, and were left wearing only their masks: we had become, in our own heads - and perhaps unbeknownst to ourselves - transvestites of the political realm.
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Jean Baudrillard (The Transparency of Evil: Essays in Extreme Phenomena)
“
If the curtain is indeed about to drop on Sapiens history, we members of one of its final generations should devote some time to answering one last question: what do we want to become? This question, sometimes known as the Human Enhancement question, dwarfs the debates that currently preoccupy politicians, philosophers, scholars and ordinary people. After all, today's debate between today's religions, ideologies, nations and classes will in all likelihood disappear along with Homo sapiens. If our successors indeed function on a different level of consciousness (or perhaps possess something beyond consciousness that we cannot even conceive), it seems doubtful that Christianity or Islam will be of interest to them, that their social organizations could be Communist or capitalist or that their genders could be male or female.
And yet the great debates of history are more important because at least the first generation of these gods would be shaped by the cultural ideas of their human designers. Would they be created in the image of capitalism, of Islam, or of feminism? The answer to this question might send them careening in entirely different directions.
Most people prefer not to think about it. Even the field of bioethics prefers to address another question: 'What is it forbidden to do?' Is it acceptable to carry out genetic experiments on living human beings? On aborted fetuses? On stem cells? Is it ethical to clone sheep? And chimpanzees? And what about humans? All of these are important questions, but it is naive to imagine that we might simply hit the brakes and stop the scientific projects that are upgrading Homo sapiens into a different kind of being. For these projects are inextricably meshed together with the Gilgamesh Project. Ask scientists why they study the genome, or try to connect a brain to a computer, or try to create a mind inside a computer. Nine out of ten times you'll get the same standard answer: we are doing it to cure diseases and save human lives. Even though the implications of creating a mind inside a computer are far more dramatic than curing psychiatric illnesses, this is the standard justification given, because nobody can argue with it. This is why the Gilgamesh Project is the flagship of science. It serves to justify everything science does. Dr Frankenstein piggybacks on the shoulders of Gilgamesh. Since it is impossible to stop Gilgamesh, it is also impossible to stop Dr Frankenstein.
The only thing we can try to do is to influence the direction scientists are taking. But since we might soon be able to engineer our desires too, the real question facing us is not 'What do we want to become?, but 'What do we want to want?' Those who are not spooked by this question probably haven't given it enough thought.
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Yuval Noah Harari (Sapiens: A Brief History of Humankind)
“
It was discussed and decided that fear would be perpetuated globally in order that focus would stay on the negative rather than allow for soul expression to positively emerge. As people became more fearful and compliant, capacity for free thought and soul expression would diminish. There is a distinct inability to exert soul expression under mind control, and evolution of the human spirit would diminish along with freedom of thought when bombarded with constant negative terrors. Whether Bush and Cheney deliberately planned to raise a collective fear over collective conscious love is doubtful. They did not think, speak, or act in those terms. Instead, they knew that information control gave them power over people, and they were hell-bent to perpetuate it at all costs. Cheney, Bush, and other global elite ushering in the New World Order totally believed in the plan mapped out by artificial intelligence. They were allowing technology to dictate global control. “Life is like a video game,” Bush once told me at the rural multi-million dollar Lampe, Missouri CIA mind control training camp complex designed for Black Ops Special Forces where torture and virtual reality technologies were used. “Since I have access to the technological source of the plans, I dictate the rules of the game.” The rules of the game demanded instantaneous response with no time to consciously think and critically analyze. Constant conscious disruption of thought through television’s burst of light flashes, harmonics, and subconscious subliminals diminished continuity of conscious thought anyway, creating a deficit of attention that could easily be refocused into video game format. DARPA’s artificial intelligence was reliant on secrecy, and a terrifying cover for reality was chosen to divert people from the simple truth. Since people perceive aliens as being physical like them, it was decided that the technological reality could be disguised according to preconceptions. Through generations of genetic encoding dating back to the beginning of man, serpents incite an innate autogenic response system in humans to “freeze” in terror. George Bush was excited at the prospects of diverting people from truth by fear through perpetuating lizard-like serpent alien misconceptions. “People fear what they don’t know anyway. By compounding that fear with autogenic fear response, they won’t want to look into Pandora’s Box.” Through deliberate generation of fear; suppression of facts under the 1947 National Security Act; Bush’s stint as CIA director during Ford’s Administration; the Warren Commission’s whitewash of the Kennedy Assassination; secrecy artificially ensured by mind control particularly concerning DARPA, HAARP, Roswell, Montauk, etc; and with people’s fluidity of conscious thought rapidly diminishing; the secret government embraced the proverbial ‘absolute power that corrupts absolutely.’ According to New World Order plans being discussed at the Grove, plans for reducing the earth’s population was a high priority. Mass genocide of so-called “undesirables” through the proliferation of AIDS4 was high on Bush’s agenda. “We’ll annihilate the niggers at their source, beginning in South and East Africa and Haiti5.” Having heard Bush say those words is by far one of the most torturous things I ever endured. Equally as torturous to my being were the discussions on genetic engineering, human cloning, and depletion of earth’s natural resources for profit. Cheney remarked that no one would be able to think to stop technology’s plan. “I’ll destroy the planet first,” Bush had vowed.
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Cathy O'Brien (ACCESS DENIED For Reasons Of National Security: Documented Journey From CIA Mind Control Slave To U.S. Government Whistleblower)
“
A clone is a branch that was clipped off of another plant. The snipped branch is encouraged to grow roots through a special process and ultimately becomes a new plant with the exact same genetic makeup as the plant it came from. The
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Madrone Stewart (Feminist Weed Farmer: Growing Mindful Medicine in Your Own Backyard)
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genes are not clones. At age seventy their genetic profile will be completely different.
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Deepak Chopra (Brotherhood: Dharma, Destiny, and the American Dream)
“
The rediscovery of Mendel's laws of heredity in the opening weeks of the 20th century sparked a scientific quest to understand the nature and content of genetic information that has propelled biology for the last hundred years. The scientific progress made [since that time] falls naturally into four main phases, corresponding roughly to the four quarters of the century."
"The first established the cellular basis of heredity: the chromosomes. The second defined the molecular basis of heredity: the DNA double helix. The third unlocked the informational basis of heredity [i.e. the genetic code], with the discovery of the biological mechanism by which cells read the information contained in genes, and with the invention of the recombinant DNA technologies of cloning and sequencing by which scientists can do the same."
The sequence of the human genome, the project asserted, marked the starting point of the "fourth phase" of genetics. This was the era of "genomics" - the assessment of the entire genomes of organisms, including humans. There is an old conundrum in philosophy that asks if an intelligent machine can ever decipher its own instruction manual. For humans, the manual was now complete. Deciphering it, reading it, and understanding it would be quite another matter.
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Siddharta Mukherjee
“
Human-rights activists are afraid that genetic engineering might be used to create supermen who will make serfs of the rest of us. Jeremiahs offer apocalyptic visions of bio-dictatorships that will clone fearless soldiers and obedient workers. The prevailing feeling is that too many opportunities are opening too quickly and that our ability to modify genes is outpacing our capacity for making wise and farsighted use of the skill.
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Yuval Noah Harari (Sapiens: A Brief History of Humankind)
“
in some crucial cases … repugnance is the emotional expression of deep wisdom, beyond reason’s power completely to articulate it.” Our instinctive revulsion toward incest, for instance, goes beyond a rational critique of the genetic dangers of inbreeding; we see it not as a mere error but in terms of “horror” and “defilement.” If cloning provokes a similar repulsion in most people, Kass writes, that proves it involves a “violation of things that we rightfully hold dear.
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Leon Kass
“
Glowing technology was also used to track success while engineering the first transgenic dog, Ruppy, short for Ruby Puppy. Ruppy was born in South Korea in 2009, one of a litter of four cloned beagles engineered by scientists at Seoul National University to express a red fluorescent protein gene. The experiment was a proof of concept; the team only intended to show that transgenic dogs could be cloned. Ruppy and her genetically identical littermates looked like perfectly normal beagles under natural light. But under ultraviolet light, they all glowed a charming, bright, ruby red. When Ruppy was mated to a non-transgenic dog, half her puppies inherited the red protein gene, indicating that the transgene had incorporated successfully into her germ line.
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Beth Shapiro (Life as We Made It: How 50,000 Years of Human Innovation Refined—and Redefined—Nature)
“
Recognition of the existence of a sex drive in female birds set the stage for Darwinian feminism, as the American biologist Patricia Gowaty dubbed it in 1997. This label may sound like an oxymoron because many feminists consider humans to be far removed from the birds and the bees. They don’t see evolutionary science and its emphasis on genetics as particularly friendly to their cause. But for biological scientists, including the feminists among us, feminism can’t escape a connection with biology. After all, there wouldn’t be any need for feminism if we didn’t have two sexes to begin with. And why do we have two sexes? Because sexual reproduction works better than its alternative, which is cloning.
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Frans de Waal (Different: Gender Through the Eyes of a Primatologist)
“
People easily believe in the transition of energy, image and voice through the air, and into their laptops and smartphones, but not in the transition of thought. And they easily accept the possibility of cloning animals and humans, or transforming them genetically, and even making hybrids with different species, but refuse to accept that we may be a hybrid of two or more alien species as well.
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Daniel Marques (The 88 Secret Codes of the Power Elite: The Complete Truth about Making Money with the Law of Attraction and Creating Miracles in Life that is Being Hidden from You with Mind Programming)
“
Similar things happen in so many diseases – the insulin-secreting cells that are lost when teenagers develop type 1 diabetes, the brain cells that are lost in Alzheimer’s disease, the cartilage producing cells that disappear during osteoarthritis – the list goes on and on. It would be great if we could replace these with new cells, identical to our own. This way we wouldn’t have to deal with all the rejection issues that make organ transplants such a challenge, or with the lack of availability of donors. Using stem cells in this way is referred to as therapeutic cloning; creating cells identical to a specific individual in order to treat a disease.
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Nessa Carey (The Epigenetics Revolution: How Modern Biology is Rewriting our Understanding of Genetics, Disease and Inheritance)
“
Reprogramming is what John Gurdon demonstrated in his ground-breaking work when he transferred the nuclei from adult toads into toad eggs. It’s what happened when Keith Campbell and Ian Wilmut cloned Dolly the Sheep by putting the nucleus from a mammary gland cell into an egg. It’s what Yamanaka achieved when he treated somatic cells with four key genes, all of which code for proteins highly expressed naturally during this reprogramming phase. The egg is a wonderful thing, honed through hundreds of millions of years of evolution to be extraordinarily effective at generating vast quantities of epigenetic change, across billions of base-pairs. None of the artificial means of reprogramming cells comes close to the natural process in terms of speed or efficiency. But the egg probably doesn’t quite do everything unaided. At the very least, the pattern of epigenetic modifications in sperm is one that allows the male pronucleus to be reprogrammed relatively easily. The sperm epigenome is primed to be reprogrammed6. Unfortunately, these priming chromatin modifications (and many other features of the sperm nucleus), are missing if an adult nucleus is reprogrammed by transferring it into a fertilised egg. That’s also true when an adult nucleus is reprogrammed by treating it with the four Yamanaka factors to create iPS cells. In both these circumstances, it’s a real challenge to completely reset the epigenome of the adult nucleus. It’s just too big a task. This is probably why so many cloned animals have abnormalities and shortened lifespans. The defects that are seen in these cloned animals are another demonstration that if early epigenetic modifications go wrong, they may stay wrong for life. The abnormal epigenetic modification patterns result in permanently inappropriate gene expression, and long-term ill-health.
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Nessa Carey (The Epigenetics Revolution: How Modern Biology is Rewriting our Understanding of Genetics, Disease and Inheritance)
“
They call it self-sacrifice when parents fight for their children, but really they’re protecting themselves, the ones who have been cloned. And that doesn’t require any moral courage; it’s just genetic egotism.
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Anonymous
“
I come from a long line of Frankensteins long before Mary Shelley was even born.” “Really. How fascinating. And what did you do for a living before you retired and moved to Black Falls?” “Oh, I haven't retired. I'm still doing research, the same as I have since I was a young man.” Mia pondered his reply. “What kind of research, may I ask?” “Genetic research, cloning, organ replacements…. Some reanimation.” Mia’s face creased with misgiving. “Mr. Frankenstein, I….” “Please. Dr. Frankenstein. I must insist,” he said emphatically.
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Billy Wells (Scary Stories: A Collection of Horror- Volume 4)
“
How much better if a few of your cells could be preserved. Real living cells, with the DNA intact. He visualized a corporation that would, for a healthy fee, freeze a little of your epithelial tissue and orbit it high-well above the Van Alien belts, maybe even higher than geosynchronous orbit. No reason to die first. Do it now, while it's on your mind. Then, at least, alien molecular biologists-or their terrestrial counterparts of the far future- could reconstruct you, clone you, more or less from scratch. You would rub your eyes, stretch, and wake up in the year ten million. Or even if nothing was done with your remains, there would still be in existence multiple copies of your genetic instructions. You would be alive in principle. In either case it could be said that you would live forever.
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Anonymous
“
When science moves faster than moral understanding, as it does today, men and women struggle to articulate their unease. In liberal societies, they reach first for the language of autonomy, fairness, and individual rights. But this part of our moral vocabulary does not equip us to address the hardest questions posed by cloning, designer children, and genetic engineering.
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Michael J. Sandel (The Case against Perfection: Ethics in the Age of Genetic Engineering)
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What, if not a death drive, would impel sexual beings towards a pre sexual form of reproduction (in the depths of our imagination, moreover, is it not precisely this scissiparous form of reproduction and proliferation based solely on contiguity that for us is death and the death drive?). And what, if not a death drive, would further impel us at the same time, on the metaphysical plane, to deny all otherness, to shun any alteration in the Same, and to seek nothing beyond the perpetuation of an identity, nothing but the transparency of a genetic inscription no longer subject even to the vicissitudes of procreation?
But enough of the death drive. Are we faced here with a phantasy of selfgenesis? No, because such phantasies always involve the figures of the mother and the father - sexed parental figures whom the subject may indeed yearn to eliminate, the better to usurp their positions, but this in no sense implies contesting the symbolic structure of procreation: if you become your own child, you are still the child of someone. Cloning, on the other hand, radically eliminates not only the mother but also the father, for it eliminates the interaction between his genes and the mother's, the imbrication of the parents' differences, and above all the joint act of procreation.
The cloner does not beget himself: he sprouts from each of his genes' segments. One may well speculate about the value of such plant-like shoots, which in effect resolve all Oedipal sexuality in favour of a 'non-human' sex, a sex based on contiguity and unmediated propagation. But at all events the phantasy of self-genesis is definitively out of the picture. Father and mother are gone, but their disappearance, far from widening an aleatory freedom for the subject, instead leaves the way clear for a matrix known as a code. No more mother, no more father: just a matrix. And it is this matrix, this genetic code, which is destined to 'give birth', from now till eternity, in an operational mode from which all chance sexual elements have been expunged.
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Jean Baudrillard (The Transparency of Evil: Essays in Extreme Phenomena)
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A clone is not a child, not a twin, not a narcissistic reflection; rather, it is the materialization of a double by genetic means - in other words, the abolition of all otherness and of the entire imaginary sphere.
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Jean Baudrillard (The Transparency of Evil: Essays in Extreme Phenomena)
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A gene segment has no more need of an imaginary mediation in order to reproduce than does an earthworm, any segment of which can reproduce autonomously as an entire worm. Any cell of an American chief executive officer likewise suffices to produce a new chief executive officer. Similarly, any portion of a hologram may become the matrix of a new complete hologram: each discrete portion of the original hologram contains all the information needed for reproduction (though a slight loss of definition may occur).
This is how the totality is eliminated. If all information is contained in each of its parts, the whole loses its significance. This means the end of the body also, the end of that unique object which we call the body, whose secret is precisely that it cannot be broken down into an accumulation of cells because it is an indivisible configuration - as witness the very fact that it is sexed.
Paradoxically, cloning is destined to continue producing sexed beings indefinitely - clones must, of course, remain identical to their model - even as it turns sex itself into a useless function; not that sex was ever a function: on the contrary, it is what makes a body a body, something which transcends all that body's diverse functions. Sex (or death) is something that transcends the entirety of the information that can be collected concerning a given body. The genetic formula, by contrast, contains all such information, but cannot transcend it. It must therefore find its own autonomous path to reproduction, independently of sexuality and death.
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Jean Baudrillard (The Transparency of Evil: Essays in Extreme Phenomena)
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With the advent of cloning, this kind of thing is occurring not just at the level of messages but also in terms of individuals. Indeed, this is exactly what happens to the body when it is conceived of as nothing more than a message, nothing more than computer fodder. In such circumstances there is no obstacle in the way of a mass reproduction of the body exactly comparable to the mass reproduction of industrial objects and mass-media images described by Benjamin. Thus reproduction precedes production, and the genetic model of the body precedes all possible bodies. An exploding technology is what presides over this reversal - that technology which Benjamin was already able to describe, in its ultimate consequences, as a total medium; but Benjamin was writing in the industrial era: by then technology itself was a gigantic prosthesis governing the generation of identical objects and images which there was no longer any way of distinguishing from one another, but it was as yet impossible to foresee the technological sophistication of our own era, which has made it possible to generate identical beings, without any means of returning to an original. The prostheses of the industrial era were still external, exotechnical, whereas those we know now are ramified and internalized -esotechnical. Ours is the age of soft technologies, the age of genetic and mental software.
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Jean Baudrillard (The Transparency of Evil: Essays in Extreme Phenomena)
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Healing
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Many other things relate also to this production of the Other - a hysterical, speculative production. Racism is one example, in its development throughout the modern era and its current recrudescence. Logically, it ought to have declined with progress and the spread of Enlightenment. But the more we learn how unfounded the genetic theory of race is, the more racism intensifies. This is because we are dealing with an artificial construction of the Other, on the basis of an erosion of the singularity of cultures (of their otherness one to another) and entry into the fetishistic system of difference. So long as there is otherness, alienness and a (possibly violent) dual relation, there is no racism properly so called. That is to say, roughly, up to the eighteenth century, as anthropological accounts attest. Once this 'natural' relation is lost, we enter upon an exponential relation with an artificial Other. And there is nothing in our culture with which we can stamp out racism, since the entire movement of that culture is towards a fanatical differential construction of the Other, and a perpetual extrapolation of the Same through the Other. Autistic culture posing as altruism.
We talk of alienation. But the worst alienation is not being dispossessed by the other, but being dispossessed of the other: it is having to produce the other in the absence of the other, and so continually to be thrown back on oneself and one's own image. If, today, we are condemned to our image (to cultivate our bodies, our 'looks', our identities, our desires), this is not because of alienation, but because of the end of alienation and the virtual disappearance of the other, which is a much worse fate. In fact, the definition of alienation is to take oneself as one's focus, as one's object of care, desire, suffering and communication. This definitive short-circuiting of the other ushers in the era of transparency. Plastic surgery becomes universal. And the surgery performed on the face and the body is merely the symptom of a more radical surgery: that performed on otherness and destiny.
What is the solution? There is no solution to this erotic trend within an entire culture; to this fascination, this whirl of denial of otherness, of all that is alien and negative; to this foreclosing of evil and this reconciliation around the Same and its multiple figures: incest, autism, twinship, cloning. All we can do is remind ourselves that seduction lies in non-reconciliation with the other, in preserving the alien status of the Other. One must not be reconciled with oneself or with one's body. One must not be reconciled with the other, one must not be reconciled with nature, one must not be reconciled with the feminine (that goes for women too). Therein lies the secret of a strange attraction.
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Jean Baudrillard (Screened Out)
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Consider these facts: the source of much of the world’s food – seeds – is mostly in the control of just four corporations; half of all the world’s cheeses are produced with bacteria or enzymes manufactured by a single company; one in four beers drunk around the world is the product of one brewer; from the USA to China, most global pork production is based around the genetics of a single breed of pig; and, perhaps most famously, although there are more than 1,500 different varieties of banana, global trade is dominated by just one, the Cavendish, a cloned fruit grown in monocultures so vast their scale can only be comprehended from the view of an aeroplane or by satellite.
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Dan Saladino (Eating to Extinction: The World's Rarest Foods and Why We Need to Save Them)
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The time when perfection was of the order of crime is over, when beneath perfect beauty something criminal lay hidden. With the cloning and recycling of the species in conformity with an ideal norm, it will no longer even be a crime to be perfect. The exactitude of the creature will shine in the genetic firmament. There will be a universal presumption of innocence and a total excommunication of evil. This technical redemption of all the taints of the species will render any new divine intervention useless. There will no longer be any Last Judgement.
Reality for us is a little like the ground for trapeze artists, who work with a net without knowing that beneath it the ground has disappeared.
In this way, screens allowed the real to slip away. In this way, icons allowed God to slip quietly away.
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Jean Baudrillard (Cool Memories V: 2000 - 2004)
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They say other species have stopped short, and that only the human species, the humanoid branch, has made its definitive breakthrough. In fact while all the others persevered in their specific forms and ended up disappearing genetically, thus leaving evolution to run its course, only the human species succeeded in surpassing itself in the simulacrum of itself - in disappearing genetically to resuscitate artificially. By perpetuating itself in a world of clones and electronic prostheses (perfect in so far as they will have eliminated every potential species, including humanity), man will thus, in a definitive act, have wiped out the natural genesis of things.
Contact with the men who wield power and authority still leaves an intang ible sense of repulsion. It's very like being in close proximity to faecal matter, the faecal embodiment of something unmentionable and you wonder what it is made of and where it acquired its historically sacred character. Why this feeling of loathing for the politician? Is it the impression of being artificially subjected to a will that is even more stupid than your own and which, by its very function, has to be crude? How can the decision-making function be performed without simplifying the mechanisms of thought?
Political charisma is precisely not that gracious charisma which emanates from the irresistible power of a pure object, such as the power of a woman, but an ungracious will which derives its power and its glory from voluntary servitude. This is true of all institutions, the military, the clerical, the medical, and more recently the psychoanalytic, but it is particularly so in politics which remains the most striking hallucination of all the weaknesses of the will.
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Jean Baudrillard (Cool Memories)
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biological clone of the Beast, given breath to speak by its creators, fully genetically engineered, much like the mythical “Golems” of ancient lore—controlled by the “secret words” inscribed on its forehead.
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Thomas Horn (Pandemonium's Engine: How the End of the Church Age, the Rise of Transhumanism, and the Coming of the bermensch (Overman) Herald Satans Imminent and Final Assault on the Creation of God)
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in 1974, scientists made a breakthrough. For the first time, they isolated and copied genes — those little segments of DNA molecules, found in the nucleus of every cell, that direct an organism to carry out its myriad functions. In other words, they cloned them. This created the potential for inserting genes into the DNA of a target cell. Here the genes would be incorporated into the cell’s genetic machinery and direct the cell to carry out some desired function. The scope of possibilities seemed almost unlimited. We could now guide plants to synthesize the insecticidal proteins or enzymes critical for the formation of natural anticancer substances.
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Joe Schwarcz (That's the Way the Cookie Crumbles: 62 All-New Commentaries on the Fascinating Chemistry of Everyday Life)
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If we are made in his image. How will that change in this next stage in our evolution? Where we have cloning of individuals and gene manipulation to enhance ourselves. Are we changing what that image is?
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James Hauenstein
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Nothing resembles itself, and holographic reproduction, like all fantasies of the exact synthesis or resurrection of the real (this also goes for scientific experimentation), is already no longer real, is already hyperreal. It thus never has reproductive (truth) value, but always already simulation value . . . Singular and murderous power of the potentialization of the truth, of the potentialization of the real. This is perhaps why twins were deified, and sacrificed, in a more savage culture: hypersimilitude was equivalent to the murder of the original, and thus to a pure non-meaning. Any classification or signification, any modality of meaning can thus be destroyed simply by logically being elevated to the nth power - pushed to its limit, it is as if all truth swallowed its own criteria of truth as one "swallows one's birth certificate" and lost all its meaning. Thus the weight of the world, or the universe, can eventually be calculated in exact terms, but initially it appears absurd, because it no longer has a reference, or a mirror in which it can come to be reflected - this totalization, which is practically equivalent to that of all the dimensions of the real in its hyperreal double, or to that of all the information on an individual in his genetic double (clone), renders it immediately pataphysical.
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Jean Baudrillard (Simulacra and Simulation)
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You could clone Elvis Presley and, while the clone would look identical, it would not have the utterly unique life experiences that made The King who he was. After all that time, effort and expense, the clone might choose to be a gardener instead of a singer! There's also the ethical dilemma of recreating all the genetic problems Elvis had due to his maternal grandparents being first cousins.
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Stewart Stafford
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There is a close connection between the key concept of the genetic code and the pathology of cancer. Cancer implies an infinite proliferation of a basic cell in complete disregard of the laws governing the organism as a whole. Similarly, in cloning, all obstacles to the extension of the reign of the Same are removed; nothing inhibits the proliferation of a single matrix. Formerly sexual reproduction constituted a barrier, but now at last it has become possible to isolate the genetic matrix of identity; consequently it will be possible to eliminate all the differences that have hitherto made individuals charming in their unpredictability.
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Jean Baudrillard (The Transparency of Evil: Essays in Extreme Phenomena)
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For some time, an arbitrary line in the sand was drawn at the end of the first trimester as the demarcation marking the beginning of "life". Of course, advances in medical technology continued to force those who stood on that line to retreat further and further toward the beginning of gestation. For instance, it has been established that a fetus has brain waves which can be measured by EEG only 40 days after conception, and merely 18 days after conception, the fetus has a measurable heart beat. In fact, they were getting so close to the beginning of gestation, i.e., conception, that the PC pro-abortion genderists then had to adopt the more ephemeral "viability" position. Of course, according to their definition of "viability", comatose patients would not be considered human being because, in some ways, a fetus is actually more "viable" than someone who is comatose. As obstetrical and gynecological medicine continued its inevitable advance, revealing more and more about the nature of a human fetus, the pro-abortion forces continued their retreat until now they do not even discuss the fetus at all. As with all politically correct positions, if a fact gets in the way, it is simply changed or ignored.
Unfortunately for the pro-abortion genderists, the fetus is a fact, a fact which is itself usually the result of "choices". Furthermore, the simple scientific fact is that at the moment of conception, the embryo is not a part of the mother's body. At that point and forever more it is a genetically distinct being with its own genetic code that is completely and totally different from every other human being who has ever lived or ever will live, including the mother. So here is the first instance of PC genderism crashing into scientific fact.
It also seems ironic that while more and more law enforcement agencies in this country are now turning to DNA identification in criminal investigations and our courts are now admitting such identification as evidence in criminal prosecution, the rights of a fetus, which has its own, distinct DNA code at the moment of conception, are still not legally recognized in all cases. Now they are recognized in some cases, for there have been instances of people being prosecuted for two murders when they have killed pregnant women. There are also cases where mothers who have given birth to babies who are addicted to illegal drugs have been prosecuted, but there are no consistent standards or guidelines. It is also a macabre irony that in this country it is illegal to destroy the egg of an American bald eagle, but the government uses our tax dollars to destroy human embryos and fetuses.
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David Thibodaux (Political Correctness: The Cloning of the American Mind)
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Human Cloning: The Least Interesting Application of Cloning Technology One of the most powerful methods of applying life’s machinery involves harnessing biology’s own reproductive mechanisms in the form of cloning. Cloning will be a key technology—not for cloning actual humans but for life-extension purposes, in the form of “therapeutic cloning.” This process creates new tissues with “young” telomere-extended and DNA-corrected cells to replace without surgery defective tissues or organs. All responsible ethicists, including myself, consider human cloning at the present time to be unethical. The reasons, however, for me have little to do with the slippery-slope issues of manipulating human life. Rather, the technology today simply does not yet work reliably. The current technique of fusing a cell nucleus from a donor to an egg cell using an electric spark simply causes a high level of genetic errors.57 This is the primary reason that most of the fetuses created by this method do not make it to term. Even those that do make it have genetic defects. Dolly the Sheep developed an obesity problem in adulthood, and the majority of cloned animals produced thus far have had unpredictable health problems.58
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Ray Kurzweil (The Singularity is Near: When Humans Transcend Biology)
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Evil Ilyan believed in love, while “Good” Ilyan thought everything he felt was a result of a genetic imperative.
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Susan Trombley (The Clone's Mate (Iriduan Test Subjects, #8))
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Every new step in the direction of simplification – toward monoculture, say, ore genetically identical plants – leads to unimaginable new complexities.(intended as challenges)
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Michael Pollan (The Botany of Desire: A Plant's-Eye View of the World)
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Prologue One day about seventy-five thousand years ago, humanity almost died. A titanic explosion in Indonesia sent up a colossal blanket of ash, smoke, and debris that covered thousands of miles. The eruption of Toba was so violent that it ranks as the most powerful volcanic event in the last twenty-five million years. It blew an unimaginable 670 cubic miles of dirt into the air. This caused large areas of Malaysia and India to be smothered by volcanic ash up to thirty feet thick. The toxic smoke and dust eventually sailed over Africa, leaving a trail of death and destruction in its wake. Imagine, for a moment, the chaos caused by this cataclysmic event. Our ancestors were terrorized by the searing heat and the clouds of gray ash that darkened the sun. Many were choked and poisoned by the thick soot and dust. Then, temperatures plunged, causing a “volcanic winter.” Vegetation and wildlife died off as far as the eye could see, leaving only a bleak, desolate landscape. People and animals were left to scavenge the devastated terrain for tiny scraps of food, and most humans died of starvation. It looked as if the entire Earth was dying. The few who survived had only one goal: to flee as far as they could from the curtain of death that descended on their world. Stark evidence of this cataclysm may perhaps be found in our blood. Geneticists have noticed the curious fact that any two humans have almost identical DNA. By contrast, any two chimpanzees can have more genetic variation between them than is found in the entire human population. Mathematically, one theory to explain this phenomenon is to assume that, at the time of the explosion, most humans were wiped out, leaving only a handful of us—about two thousand people. Remarkably, this dirty, raggedy band of humans would become the ancestral Adams and Eves who would eventually populate the entire planet. All of us are almost clones of one another, brothers and sisters descended from a tiny, hardy group of humans who could have easily fit inside a modern hotel ballroom. As they trekked across the barren landscape, they had no idea that one day, their descendants would dominate every corner of our planet.
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Michio Kaku (The Future of Humanity: Terraforming Mars, Interstellar Travel, Immortality, and Our Destiny Beyond Earth)