Fatty Liver Quotes

The simplest way to look at all these associations, between obesity, heart disease, type 2 diabetes, metabolic syndrome, cancer, and Alzheimer's (not to mention the other the conditions that also associate with obesity and diabetes, such as gout, asthma, and fatty liver disease), is that what makes us fat - the quality and quantity of carbohydrates we consume - also makes us sick.

We have body clocks not just in the brain but all over—in our pancreas, liver, heart, kidneys, fatty tissue, muscle, virtually everywhere—and these operate to their own timetables, dictating when hormones are released or organs are busiest or most relaxed. Your reflexes, for instance, are at their sharpest in mid-afternoon, while blood pressure peaks toward evening. Men tend to pump more testosterone early in the morning than later in the day.

Remember this quotation from Jimmy Moore: “One way to remember that eating carbohydrates leads to an increase in blood and liver fat is to compare it to the French delicacy foie gras, a “fatty liver,” created by force-feeding carbohydrate (corn or, in Roman times, figs) to a goose. The same thing happens in humans.

Fatty liver is a completely reversible process. Emptying the liver of its surplus glucose and dropping insulin levels returns the liver to normal. Hyperinsulinemia drives DNL, which is the primary determinant of fatty liver disease. Normalizing insulin levels reverses the fatty liver. Refined carbohydrates, which cause large increases in insulin, are far more sinister than dietary fat. High carbohydrate intake can increase DNL tenfold, whereas high fat consumption, with correspondingly low carbohydrate intake, does not change hepatic fat production

Eating sugar in excess of what can be immediately burned causes it to be stored in the liver in the form of glucose (glycogen). Since the liver’s capacity is limited, a daily intake of refined sugar soon causes the liver to exceed its ability to store sugar, and the excess glycogen is returned to the blood in the form of fatty acids. These are taken to every part of the body and stored as fat in the most inactive areas: the belly, the buttocks, the breasts, and the thighs.

Even though a strict reading of a Paleolithic diet would include cannibalism, it is a practice that I have to discourage. Modern people have a much higher ratio of omega-6 to omega-3 fatty acids due to their grain-based diets; carry a wide variety of chronic infections; have destroyed their liver with excessive consumption of alcohol and fructose; and contain many environmental toxins. That said, if one were to incorporate cannibalism into ‘eating paleo,’ it would be healthiest to eat people who strictly adhered to the guidelines in this book.

The most popular game is Cholesterol Canasta, where the plague patients, vivisection victims, and ambulant biohazard bags try to one-up each other with their hellish blood panels and urine tests. For a long time, the undisputed winner was a two-hundred-and-fifty-kilo diabetic with renal insufficiency, fatty liver disease, and food poisoning. The only infection he didn’t have was HIV..

Because the insulin level in the bloodstream is determined primarily by the carbohydrates that are consumed—their quantity and quality, as I’ll discuss—it’s those carbohydrates that ultimately determine how much fat we accumulate. Here’s the chain of events: 1.  You think about eating a meal containing carbohydrates. 2. You begin secreting insulin. 3. The insulin signals the fat cells to shut down the release of fatty acids (by inhibiting HSL) and take up more fatty acids (via LPL) from the circulation. 4. You start to get hungry, or hungrier. 5. You begin eating. 6. You secrete more insulin. 7. The carbohydrates are digested and enter the circulation as glucose, causing blood sugar levels to rise.§ 8. You secrete still more insulin. 9. Fat from the diet is stored as triglycerides in the fat cells, as are some of the carbohydrates that are converted into fat in the liver. 10.  The fat cells get fatter, and so do you. 11.  The fat stays in the fat cells until the insulin level drops. If

These visceral (belly) fat cells behave differently than fat elsewhere in the body in two important ways.25 First, they are several times more sensitive to hormones and thus tend to be more metabolically active, which means they are capable of storing and releasing fat more rapidly than fat cells in other parts of the body. Second, when visceral cells release fatty acids (something fat cells do all the time), they dump the molecules almost straight into the liver, where the fat accumulates and eventually impairs the liver’s ability to regulate the release of glucose into the blood. An excess of belly fat (a paunch) is therefore a much greater risk factor for metabolic disease than a high BMI.

Eat carbohydrates and blood sugar rises. Every first-year medical student knows this, every nurse or diabetes educator knows this, every person with diabetes who performs finger-stick blood sugars before and after meals knows this. Eat any food with more than just a few grams of carbohydrates and blood sugar will rise; the more carbohydrates you eat, the higher blood sugar will rise. Everyone also knows that foods like butter do not raise blood sugar, nor will a fatty cut of meat, olives, green bell peppers, broccoli, or chicken liver. And since the 1980s, when the sharp upward climb in type 2 diabetes (and obesity) began, the only component of diet that has increased is carbohydrates, not fat or proteins.4

There is one notable exception to Jablonski and Chaplin’s equation—and it’s the exception that proves the rule. The Inuit—the indigenous people of the subarctic—are dark-skinned, despite the limited sunlight of their home. If you think something fishy’s going on here, you’re right. But the reason they don’t need to evolve the lighter skin necessary to ensure sufficient vitamin D production is refreshingly simple. Their diet is full of fatty fish—which just happens to be one of the only foods in nature that is chock-full of vitamin D. They eat vitamin D for breakfast, lunch, and dinner, so they don’t need to make it. If you ever had a grandmother from the Old World try to force cod liver oil down your throat, she was onto something for the same reason—since it’s full of vitamin D, cod liver oil was one of the best ways to prevent rickets, especially before milk was routinely fortified with it.   IF YOU’RE WONDERING how people who have dark skin make enough vitamin D despite the fact that their skin blocks all those ultraviolet rays, you’re asking the right questions. Remember, ultraviolet rays that penetrate the skin destroy folate—and ultraviolet rays that penetrate the skin are necessary to create vitamin D. Dark skin evolved to protect folate, but it didn’t evolve

Carbohydrates are not required in a healthy human diet. Another way to say this (as proponents of carbohydrate restriction have) is that there is no such thing as an essential carbohydrate. Nutritionists will say that 120 to 130 grams of carbohydrates are required in a healthy diet, but this is because they confuse what the brain and central nervous system will burn for fuel when diets are carbohydrate rich—120 to 130 grams daily—with what we actually have to eat. If there are no carbohydrates in the diet, the brain and central nervous system will run on molecules called “ketones.” These are synthesized in the liver from the fat we eat and from fatty acids, mobilized from the fat tissue because we’re not eating carbohydrates and insulin levels are low, and even from some amino acids. With no carbohydrates in the diet, ketones will provide roughly three-quarters of the energy that our brains use. And this is why severely carbohydrate-restricted diets are known as “ketogenic” diets. The rest of the energy required will come from glycerol, which is also being released from the fat tissue when the triglycerides are broken down into their component parts, and from glucose synthesized in the liver from the amino acids in protein. Because a diet that doesn’t include fattening carbohydrates will still include plenty of fat and protein, there will be no shortage of fuel for the brain.

nonalcoholic fatty liver disease has become the most common chronic liver disease in the world, increasing from 25 percent of the global population in 1990 to close to 40 percent by 2019. NAFLD is full-blown metabolic dysfunction in kids and adults, representing liver cells filling with fat, which worsens insulin resistance. Key contributors are processed foods, refined sugars, refined grains, sweet beverages, high-fructose corn syrup, fast food, low fiber and phytochemical intake, habitual eating close to bedtime, sedentary behavior, and oxidative stress. Liver transplants have gone up close to 50 percent in the past fifteen years, and while alcohol and hepatitis C used to be the leading causes, now NAFLD is taking the lead in women as the cause of liver failure and is a top cause for men. Fatty liver disease is now the most common cause of liver transplant in young adults in the United States. We are failing our children.

There’s no getting around the fact that alcohol is very damaging to your system. The majority of alcohol consumed is metabolized by the liver. The rest of your body’s functions can become greatly impaired while the majority of your energy is focused on helping the liver process the alcohol. This in turn causes free radicals, free fatty acids, and LDL (bad cholesterol) numbers to soar. Insulin resistance, liver inflammation, and accelerated aging are some of the many side effects that occur with consistent abuse.

Myth #3: Fasting Causes Low Blood Sugar Sometimes people worry that blood sugar will fall very low during fasting and they will become shaky and sweaty. Luckily, this does not actually happen. Blood sugar level is tightly monitored by the body, and there are multiple mechanisms to keep it in the proper range. During fasting, our body begins by breaking down glycogen (remember, that’s the glucose in short-term storage) in the liver to provide glucose. This happens every night as you sleep to keep blood sugars normal as you fast overnight. FASTING ALL-STARS AMY BERGER People who engage in fasting for religious or spiritual purposes often report feelings of extreme clear-headedness and physical and emotional well-being. Some even feel a sense of euphoria. They usually attribute this to achieving some kind of spiritual enlightenment, but the truth is much more down-to-earth and scientific than that: it’s the ketones! Ketones are a “superfood” for the brain. When the body and brain are fueled primarily by fatty acids and ketones, respectively, the “brain fog,” mood swings, and emotional instability that are caused by wild fluctuations in blood sugar become a thing of the past and clear thinking is the new normal. If you fast for longer than twenty-four to thirty-six hours, glycogen stores become depleted. The liver now can manufacture new glucose in a process called gluconeogenesis, using the glycerol that’s a by-product of the breakdown of fat. This means that we do not need to eat glucose for our blood glucose levels to remain normal. A related myth is that brain cells can only use glucose for energy. This is incorrect. Human brains, unique amongst animals, can also use ketone bodies—particles that are produced when fat is metabolized—as a fuel source. This allows us to function optimally even when food is not readily available. Ketones provide the majority of the energy we need. Consider the consequences if glucose were absolutely necessary for brain function. After twenty-four hours without food, glucose stored in our bodies in the form of glycogen is depleted. At that point, we’d become blubbering idiots as our brains shut down. In the Paleolithic era, our intellect was our only advantage against wild animals with their sharp claws, sharp fangs, and bulging muscles. Without it, humans would have become extinct long ago. When glucose is not available, the body begins to burn fat and produce ketone bodies, which are able to cross the blood-brain barrier to feed the brain cells. Up to 75 percent of the brain’s energy requirements can be met by ketones. Of course, that means that glucose still provides 25 percent of the brain’s energy requirements. So does this mean that we have to eat for our brains to function?

DIET FOR LONGEVITY Avoid all junk food and salty, fried, and fatty foods. Stay away from meat, alcohol, coffee, caffeine, and sugar. Check for food sensitivities, particularly wheat and dairy. Therapeutic foods include cilantro, onion, seaweeds, and ginger, which help bind and excrete heavy metals. SUPPLEMENTS FOR LONGEVITY ReMag: (Picometer-ionic)150 mg 2–3 times a day and/or Magnesium citrate: 300 mg two times per day Magnesium oil applied to the skin (don’t rub in), 10–20 sprays per day (each spray carries about 20 mg of magnesium). Calcium: dietary and/or bone broth, 700mg (see this page for food lists and this page for bone broth recipe) ReLyte: Mineral-Electrolyte Solution. ½ tsp three times a day Vitamin E as mixed tocopherols: 400 IU daily Vitamin C: 1,000 mg twice per day Vitamin B complex: 2 per day. Food-based, Grown by Nature Vitamin B12: 1,000 mcg intramuscularly weekly Vitamin D, A, and K2 from Blue Ice Royal (fermented cod liver oil and butter oil: 2 capsules per day) Vitamin D: 20 minutes of sun exposure daily if possible Lecithin granules: 2 tbsp per day Flaxseed oil: 1–2 tbsp per day Ginkgo biloba and gotu kola are two herbs that can improve cerebral circulation.

We start with a next-generation miso soup: Kyoto's famous sweet white miso whisked with dashi made from lobster shells, with large chunks of tender claw meat and wilted spinach bobbing on the soup's surface. The son takes a cube of topflight Wagyu off the grill, charred on the outside, rare in the center, and swaddles it with green onions and a scoop of melting sea urchin- a surf-and-turf to end all others. The father lays down a gorgeous ceramic plate with a poem painted on its surface. "From the sixteenth century," he tells us, then goes about constructing the dish with his son, piece by piece: First, a chunk of tilefish wrapped around a grilled matsutake mushroom stem. Then a thick triangle of grilled mushroom cap, plus another grilled stem the size of a D-sized battery, topped with mushroom miso. A pickled ginger shoot, a few tender soybeans, and the crowning touch, the tilefish skin, separated from its body and fried into a ripple wave of crunch. The rice course arrives in a small bamboo steamer. The young chef works quickly. He slices curtains of tuna belly from a massive, fat-streaked block, dips it briefly in house-made soy sauce, then lays it on the rice. Over the top he spoons a sauce of seaweed and crushed sesame seeds just as the tuna fat begins to melt into the grains below. A round of tempura comes next: a harvest moon of creamy pumpkin, a gold nugget of blowfish capped with a translucent daikon sauce, and finally a soft, custardy chunk of salmon liver, intensely fatty with a bitter edge, a flavor that I've never tasted before. The last savory course comes in a large ice block carved into the shape of a bowl. Inside, a nest of soba noodles tinted green with powdered matcha floating in a dashi charged with citrus and topped with a false quail egg, the white fashioned from grated daikon.

REPROGRAMMING MY BIOCHEMISTRY A common attitude is that taking substances other than food, such as supplements and medications, should be a last resort, something one takes only to address overt problems. Terry and I believe strongly that this is a bad strategy, particularly as one approaches middle age and beyond. Our philosophy is to embrace the unique opportunity we have at this time and place to expand our longevity and human potential. In keeping with this health philosophy, I am very active in reprogramming my biochemistry. Overall, I am quite satisfied with the dozens of blood levels I routinely test. My biochemical profile has steadily improved during the years that I have done this. For boosting antioxidant levels and for general health, I take a comprehensive vitamin-and-mineral combination, alpha lipoic acid, coenzyme Q10, grapeseed extract, resveratrol, bilberry extract, lycopene, silymarin (milk thistle), conjugated linoleic acid, lecithin, evening primrose oil (omega-6 essential fatty acids), n-acetyl-cysteine, ginger, garlic, l-carnitine, pyridoxal-5-phosphate, and echinacea. I also take Chinese herbs prescribed by Dr. Glenn Rothfeld. For reducing insulin resistance and overcoming my type 2 diabetes, I take chromium, metformin (a powerful anti-aging medication that decreases insulin resistance and which we recommend everyone over 50 consider taking), and gymnema sylvestra. To improve LDL and HDL cholesterol levels, I take policosanol, gugulipid, plant sterols, niacin, oat bran, grapefruit powder, psyllium, lecithin, and Lipitor. To improve blood vessel health, I take arginine, trimethylglycine, and choline. To decrease blood viscosity, I take a daily baby aspirin and lumbrokinase, a natural anti-fibrinolytic agent. Although my CRP (the screening test for inflammation in the body) is very low, I reduce inflammation by taking EPA/DHA (omega-3 essential fatty acids) and curcumin. I have dramatically reduced my homocysteine level by taking folic acid, B6, and trimethylglycine (TMG), and intrinsic factor to improve methylation. I have a B12 shot once a week and take a daily B12 sublingual. Several of my intravenous therapies improve my body’s detoxification: weekly EDTA (for chelating heavy metals, a major source of aging) and monthly DMPS (to chelate mercury). I also take n-acetyl-l-carnitine orally. I take weekly intravenous vitamins and alpha lipoic acid to boost antioxidants. I do a weekly glutathione IV to boost liver health. Perhaps the most important intravenous therapy I do is a weekly phosphatidylcholine (PtC) IV, which rejuvenates all of the body’s tissues by restoring youthful cell membranes. I also take PtC orally each day, and I supplement my hormone levels with DHEA and testosterone. I take I-3-C (indole-3-carbinol), chrysin, nettle, ginger, and herbs to reduce conversion of testosterone into estrogen. I take a saw palmetto complex for prostate health. For stress management, I take l-theonine (the calming substance in green tea), beta sitosterol, phosphatidylserine, and green tea supplements, in addition to drinking 8 to 10 cups of green tea itself. At bedtime, to aid with sleep, I take GABA (a gentle, calming neuro-transmitter) and sublingual melatonin. For brain health, I take acetyl-l-carnitine, vinpocetine, phosphatidylserine, ginkgo biloba, glycerylphosphorylcholine, nextrutine, and quercetin. For eye health, I take lutein and bilberry extract. For skin health, I use an antioxidant skin cream on my face, neck, and hands each day. For digestive health, I take betaine HCL, pepsin, gentian root, peppermint, acidophilus bifodobacter, fructooligosaccharides, fish proteins, l-glutamine, and n-acetyl-d-glucosamine. To inhibit the creation of advanced glycosylated end products (AGEs), a key aging process, I take n-acetyl-carnitine, carnosine, alpha lipoic acid, and quercetin. MAINTAINING A POSITIVE “HEALTH SLOPE” Most important,

Choose from beef, pork, lamb, fish, chicken, turkey, buffalo, ostrich, and wild game. Consider pasture-/grass-fed, free-range, and organic sources whenever possible to minimize exposure to antibiotic residues, hormones, and other contaminants, as well as to do your part in encouraging a return to more humane livestock practices. There is no need to look for lean cuts; look for fatty cuts, often less expensive and full of the fats you need that facilitate success in this lifestyle. And try to overcome the modern aversion to organ meats, such as liver, heart, and tongue, the most nutritious components of all, especially liver and heart.

The study found that a ketogenic diet can lead to insulin resistance, fatty liver, a pro-inflammatory state, type 2 diabetes, heart disease, and unhealthy fat regulation, as well as elevated levels of cholesterol, triglycerides, and leptin.

Aged garlic extract 600 mg one to three times a day. Aged garlic extract is used to protect the heart and blood vessels, and is reported to help decrease oxidative stress markers, including those related to blood sugar regulation problems. Aged garlic has also been reported to reduce liver enzymes and fatty liver, as well as decrease the formation of advanced glycation end-products (AGEs), which are implicated in various health problems, such as heart disease, kidney problems, and cancer.

One example of the Prevention Paradox occurs in the first weeks when people with high LDL or “bad” cholesterol start taking fish oil supplements. Researchers found that using fish oil (which is high in omega-3 fatty acids from mackerel, herring, tuna, halibut, salmon, cod liver, and even whale blubber) is associated with a wide range of changes in LDL levels across the population, from down by 50 percent to up by a whopping increase of 87 percent.6 Researchers have dug deeper to demonstrate that people who supplemented their diets with the so-called healthy fats found in fish oil actually had a greater negative change in their cholesterol levels if they were carriers of a gene variant called APOE4. Meaning that supplementing with fish oil may be good for some and very bad for other people’s cholesterol levels depending on which genes they’ve inherited.

Another result of excess dietary fructose is that it causes fat deposits in the liver, just as it does in alcoholics. As such, it is referred to as “nonalcoholic fatty liver disease.” And, like fatty liver from overconsumption of alcohol, fatty liver from overconsumption of fructose may eventually lead to the disruption of liver function and even liver failure

A single molecule plays the pivotal role in the system. It goes by a number of names, the simplest being glycerol phosphate. This glycerol-phosphate molecule is produced from glucose when it is used for fuel in the fat cells and the liver, and it, too, can be burned as fuel in the cells. But glycerol phosphate is also an essential component of the process that binds three fatty acids into a triglyceride. It provides the glycerol molecule that links the fatty acids together.†116 In other words, a product of carbohydrate metabolism—i.e., burning glucose for fuel—is an essential component in the regulation of fat metabolism: storing fat in the fat tissue. In fact, the rate at which fatty acids are assembled into triglycerides, and so the rate at which fat accumulates in the fat tissue, depend primarily on the availability of glycerol phosphate. The more glucose that is transported into the fat cells and used to generate energy, the more glycerol phosphate will be produced.

Liver dysfunction can run in families, like the iron-overload disease hemochromatosis. It can be caused by infections that can lead to liver cancer, or it can stem from drugs—most often inadvertent or intentional overdoses of Tylenol.4 The most common causes, however, are drink and food: alcoholic liver disease and fatty liver disease.

The bottom line is that excess fructose is changed into fat in the liver. High levels of fructose will cause fatty liver. Fatty liver is absolutely crucial to the development of insulin resistance in the liver.

Here are a few notable things that can spark inflammation and depress the function of your liver: Alcohol overload—This is relatively well-known. Your liver is largely responsible for metabolizing alcohol, and drinking too much liquid courage can send your liver running to cry in a corner somewhere. Carbohydrate bombardment—Starches and sugar have the fastest ability to drive up blood glucose, liver glycogen, and liver fat storage (compared to their protein and fat macronutrient counterparts). Bringing in too many carbs, too often, can elicit a wildfire of fat accumulation. In fact, one of the most effective treatments for reversing NAFLD is reducing the intake of carbohydrates. A recent study conducted at KTH Royal Institute of Technology and published in the journal Cell Metabolism had overweight test subjects with high levels of liver fat reduce their ratio of carbohydrate intake (without reducing calories!). After a short two-week study period the subjects showed “rapid and dramatic” reductions of liver fat and other cardiometabolic risk factors. Too many medications—Your liver is the top doc in charge of your body’s drug metabolism. When you hear about drug side effects on commercials, they are really a direct effect of how your liver is able to handle them. The goal is to work on your lifestyle factors so that you can be on as few medications as possible along with the help of your physician. Your liver will do its best to support you either way, but it will definitely feel happier without the additional burden. Too many supplements—There are several wonderful supplements that can be helpful for your health, but becoming an overzealous natural pill-popper might not be good for you either. In a program funded by the National Institutes of Health, it was found that liver injuries linked to supplement use jumped from 7 percent to 20 percent of all medication/supplement-induced injuries in just a ten-year time span. Again, this is not to say that the right supplements can’t be great for you. This merely points to the fact that your liver is also responsible for metabolism of all of the supplements you take as well. And popping a couple dozen different supplements each day can be a lot for your liver to handle. Plus, the supplement industry is largely unregulated, and the additives, fillers, and other questionable ingredients could add to the burden. Do your homework on where you get your supplements from, avoid taking too many, and focus on food first to meet your nutritional needs. Toxicants—According to researchers at the University of Louisville, more than 300 environmental chemicals, mostly pesticides, have been linked to fatty liver disease. Your liver is largely responsible for handling the weight of the toxicants (most of them newly invented) that we’re exposed to in our world today. Pesticides are inherently meant to be deadly, but just to small organisms (like pests), though it seems to be missed that you are actually made of small organisms, too (bacteria

spoke to Jason and immediately started fasting and applying his principles of good nutrition, eating a variety of low-carb, healthy-fat, whole foods. Within weeks, I realized that, for my whole life, just about everything I’d learned about nutrition was wrong. It’s been eight years since I began following Dr. Fung’s recommendations, and I’ve maintained an eighty-six-pound weight loss. I have completely reversed my type 2 diabetes, fatty liver, and PCOS.

The more of these sugars we consume, and the longer we have them in our diet, the more our bodies apparently adapt by converting them to fat. Our “pattern of fructose metabolism” changes with time, as the British biochemist and fructose expert Peter Mayes says. Not only will this cause us to accumulate fat directly in the liver—a condition known as “fatty liver disease”—but it apparently causes our muscle tissue to become resistant to insulin through a kind of domino effect that is triggered by the liver cells’ resistance.

It turns out that high-carb diets cause the liver to make dangerous fats called triglycerides, which raise the risk of heart disease.2 Some of the triglycerides stay stuck in the liver, which can lead to fatty liver disease.

The mechanisms that underlie the increased production of ketones recently have been discussed in a number of reviews on DKA.12,14 The combination of insulin deficiency and increased concentration of counterregulatory hormones causes the activation of hormone-sensitive lipase in adipose tissue. The increased activity of tissue lipase causes a breakdown of triglyceride into glycerol and free fatty acids (FFAs). In the liver, FFAs are oxidized to ketone bodies, a process predominantly stimulated by glucagon.15 Increased concentration of glucagon lowers the hepatic levels of malonyl coenzyme A (CoA) by blocking the conversion of pyruvate to acetyl CoA through inhibition of acetyl CoA carboxylase,15 the first rate-limiting enzyme in de novo fatty acid synthesis. Malonyl CoA inhibits carnitine palmitoyl-transferase I (CPT I), the rate-limiting enzyme for transesterification of fatty acyl CoA to fatty acyl carnitine, allowing oxidation of fatty acid to ketone bodies.15 The increased fatty acyl CoA in DKA leads to increased ketogenesis in DKA.15 Increased production of ketone bodies (acetoacetate and β-hydroxybutyrate) leads to ketonemia and metabolic acidosis.

This is an eel roll-up skewer. It's thinly sliced eel meat wrapped around a skewer." "What do you mean by the eel meat?" "Take a look at the diagram behind you." "Hmm! It's been separated into so many different parts! It's soft, meaty and fatty... I can enjoy the flavor of the eel to the fullest!" "I must say... this skewer tastes good." "The taste of the eel is a lot richer since it hasn't been steamed like a Tokyo-style kabayaki! And it's a lot more soft and succulent than the kansai-style kabayaki!" "It's the very essence of the eel's flavor." "This is the liver. I can only get one liver out of an eel, so I can only provide the customers with a limited amount each day." "Oh, but isn't the liver the guts?" Ah, look at the diagram. At my place, the liver is one specific part while the guts are the whole thing." "Ooh, I see. That's what it means." "Animal guts have a distinct smell to them. But the eel liver has no smell at all!" "Unlike an ordinary liver skewer... I've taken out the gall bladder, so it's not bitter. Next come the grilled ribs. The ribs are the abdominal bones in the eel that you get rid of when making kabayaki. I skewer and grill them.

This one is skewered guts. It's all the guts except the liver." "It's got that unique texture of a gut, with a slightly bitter taste!" "The flavor of the guts tends to seep out when you make soup with it, but this retains all its refreshing original flavor!" "This is a fin skewer. As you can guess from its name, it's the dorsal fin of the eel... ... wrapped around a skewer with ribs and garlic chives." "This is my favorite one!" "They throw these parts away when they make kabayaki." "Ah! I understand why this is your favorite, Yamaoka-san! The eel and the garlic chives create a rich, savory flavor!" "I never thought eel and garlic chives would go so well together!" "The dorsal fin of a left-eyed flounder is called an engawa, and it's considered a delicacy. It's the most active part of the fish's body, so it's fatty and good to eat." "The same goes for the eel." "This one is the collar. It's the meat around the neck, below the eyes... ... which I cut open and skewered after taking the head off. The head bone is very tough, so this is the only part of the eel I throw away." "Hmm, so it's called the "collar" because it's the area around the neck." "It has a complex flavor to it too. It's totally different from the stomach meat, the guts or the dorsal fin!" "It kind of tastes like a mixture of fish and lamb meat! There are so many other skewers, right?!" "Yahata-maki, which is eel meat wrapped around burdock. Tanzaku, where the meat has been cut like strips of paper. Smoked eel. And of course, we can't forget the famous kabayaki.

On the other hand, intact fiber—found in Real Food—has many benefits, and not just short-chain fatty acids (SCFAs). In the processed food industry, the germ of the grain (the nucleic acids, flavonoids, polyphenols) is removed along with the fiber because they can go rancid (see Chapter 19). Protecting the liver means maintaining the fiber and keeping the germ intact as well. Two simple precepts—protect the liver, feed the gut. Real Food (low-sugar, high-fiber) does both. Processed food (high-sugar, low-fiber) does neither. Processed food is the primary suspect in our current health and healthcare debacle, because it doesn’t improve our eight subcellular pathologies, our three nutrient-sensing enzymes, and our two physiologic precepts.

The list of oils with the highest concentration of PUFAs and that can be the most harmful are soybean oil, corn oil, safflower oil, grape seed oil, sesame seed, nut oils (peanut, walnut, almond, etc.), flaxseed, fish oil, cod liver oil, evening primrose, borage oils, and, yes, this even includes Omega-3 (EPA and DHA) and Omega-6, also known as the “essential fatty acids.

A Family Affair: Essential Fatty Acids More chemical clues to the nature of alcoholism come from research focusing on alcoholics with at least one grandparent who was Welsh, Irish, Scottish, Scandinavian, or native American. Typically, these alcoholics have a history of depression going back to childhood and close relatives who suffered from depression or schizophrenia. Some may have relatives who committed suicide. There also may be a family history of eczema, cystic fibrosis, premenstrual syndrome, diabetes, irritable bowel syndrome, or benign breast disease. The common denominator here is a genetic abnormality in the way the body handles certain essential fatty acids (EFAs) derived from foods. Normally, these EFAs are converted in the brain to various metabolites such as prostaglandin E1 (PGE1), which plays a vital role in the prevention of depression, convulsions, and hyperexcitability. When the EFA conversion process is defective, brain levels of prostaglandin E1 are lower than normal, which results in depression. In affected individuals, alcohol acts as a double-edged sword. It activates the PGE1 within the brain, which immediately lifts depression and creates feelings of well-being. Because the brain cannot make new PGE1 efficiently, its meager supply of PGE1 is gradually depleted. Over time, the ability of alcohol to lift depression slowly diminishes. Several years ago, researchers hit upon a solution to this problem. They discovered that a natural substance, oil of evening primrose, contains large amounts of gamma-linolenic acid (GLA), which can help the brain convert EFAs to PGE1. The results are quite dramatic. In a recent study in Scotland, researcher David Horrobin, M.D., matched two groups of alcoholics whose EFA levels were 50 percent below normal. The first group got EFA replacement, the second, a placebo. Marked differences between the two groups emerged in the withdrawal stage. The group that got EFA replacement had far fewer symptoms, while the placebo group displayed the full range of withdrawal symptoms associated with prostaglandin deficiency: tremors, irritability, tension, hyperexcitability, and convulsions. At the outset of the study, members of both groups had some degree of alcohol-related liver damage. Three months later, the researchers found that liver function among the EFA replacement group was almost normal. There was no significant improvement among the placebo group. A year later, the placebo group was still deficient in the natural ability to convert essential fatty acids into PGE1. What’s more, only 28 percent of this group had remained sober; the rest had resumed drinking. Results were dramatically better among the EFA replacement group: 83 percent remained sober and depression free.

Today I saw my inner planet: a cracked rib, air in the lungs, fatty liver and an open heart.

Drinking just one can of soda a day appears to raise the odds of getting fatty liver disease by 45 percent.25 Meanwhile, those who eat the meat equivalent of fourteen chicken nuggets or more daily have nearly triple the rate of fatty liver disease compared to people who eat seven nuggets’ worth or less.26

Corn is fed to animals to make fatty liver (foie gras) and to fatten them up

the Duke-NUS Graduate Medical School found that drinking four or more cups of coffee daily could help prevent non-alcoholic fatty liver disease (NAFLD).[7]

Use Cod Liver Oil According to studies, the fatty acids found abundantly in the oil can switch off enzymes that break down cartilage (the smooth protective coating in our bodies

when something is ever present, you stop responding to it. This insulin resistance contributes not only to type 2 diabetes, fatty liver, and metabolic syndrome, but also to Alzheimer’s disease.

The yolk of an egg is incredibly nutritious. It contains 100 percent of the carotenoids; essential fatty acids; fat-soluble vitamins A, E, D, and K that our body requires; and more than 90 percent of the calcium, iron, phosphorus, zinc, thiamine, folate, B12, pantothenic acid, as well as the majority of the copper, manganese, and selenium our body requires. They are also excellent sources of lutein and zeaxanthin, which evidence has shown are highly protective against developing macular degeneration—the major cause of blindness in the elderly. Since most people don’t eat liver, egg yolks are the only major source of choline, which helps to protect against fatty liver disease, which afflicts about one-third of Americans. Additionally, animal studies indicate that when you get three times more than the recommended amount of choline early in life, you can have lifelong protection against senility and dementia, along with major boosts in memory and mental performance throughout your life. Eggs yolks are primarily feared by people because of their cholesterol content, but they are jam-packed with really important nutrients, some of which are very difficult to get anywhere else in your diet.” –Dr. Chris Masterjohn

This is precisely why T2DM, unlike virtually any other disease, affects every single part of the body. Every organ suffers the long-term effects of the excessive sugar load. Your eyes rot – and you go blind. Your kidneys rot – and you need dialysis. You heart rots – and you get heart attacks and heart failure. Your brain rots – and you get Alzheimer’s disease. Your liver rots – and you get fatty liver disease and cirrhosis. Your legs rot – and you get diabetic foot ulcers. Your nerves rot – and you get diabetic neuropathy. No part of your body is spared.

Though glucose is a primary fuel for the brain, it is not, however, the only fuel, and dietary carbohydrates are not the only source of that glucose. If the diet includes less than 130 grams of carbohydrates, the liver increases its synthesis of molecules called ketone bodies, and these supply the necessary fuel for the brain and central nervous system. If the diet includes no carbohydrates at all, ketone bodies supply three-quarters of the energy to the brain. The rest comes from glucose synthesized from the amino acids in protein, either from the diet or from the breakdown of muscle, and from a compound called glycerol that is released when triglycerides in the fat tissue are broken down into their component fatty acids. In these cases, the body is technically in a state called ketosis, and the diet is often referred to as a ketogenic diet.

FALLING OUT OF KETOSIS Life happens and no one is perfect, so more likely than not, you are occasionally going to fall out of ketosis. It is not the end of the world. The key is getting back into ketosis as soon as you can. Here are some techniques to help you get back into ketosis quickly. Fast: Try to not eat for at least 16 to 24 hours after falling out of ketosis. Pump up your MCT intake: MCTs are medium-chain triglycerides, which can be found in coconut oil, grass-fed butter, or as a concentrated oil in your health food store. MCTs are a form of saturated fatty acids that can be quickly absorbed and converted into ketone bodies by your liver. Get moving: Being physically active can help you get into ketosis. When you exercise, you can deplete your body of its glycogen stores and force it to produce ketones for fuel. The bottom line: To make this a true lifestyle, always keep moving forward, and don’t let one slipup stop your progress. Be patient, don’t be too hard on yourself, and keep your focus on the long term.

It’s Thanksgiving, and you’ve eaten with porcine abandon. Your bloodstream is teeming with amino acids, fatty acids, glucose. It’s far more than you need to power you over to the couch in a postprandial daze. What does your body do with the excess? This is crucial to understand because, basically, the process gets reversed when you’re later sprinting for your life. To answer this question, it’s time we talked finances, the works—savings accounts, change for a dollar, stocks and bonds, negative amortization of interest rates, shaking coins out of piggy banks—because the process of transporting energy through the body bears some striking similarities to the movement of money. It is rare today for the grotesquely wealthy to walk around with their fortunes in their pockets, or to hoard their wealth as cash stuffed inside mattresses. Instead, surplus wealth is stored elsewhere, in forms more complex than cash: mutual funds, tax-free government bonds, Swiss bank accounts. In the same way, surplus energy is not kept in the body’s form of cash—circulating amino acids, glucose, and fatty acids—but stored in more complex forms. Enzymes in fat cells can combine fatty acids and glycerol to form triglycerides (table). Accumulate enough of these in the fat cells and you grow plump. Meanwhile, your cells can stick series of glucose molecules together. These long chains, sometimes thousands of glucose molecules long, are called glycogen. Most glycogen formation occurs in your muscles and liver. Similarly, enzymes in cells throughout the body can combine long strings of amino acids, forming them into proteins. The hormone that stimulates the transport and storage of these building blocks into target cells is insulin. Insulin is this optimistic hormone that plans for your metabolic future. Eat

Once You’re in Keto, How Can You Keep It Going Without Fasting? The short answer is: Eat a boatload of fat (~1.5 to 2.5 g per kilogram of body weight), next-to-no carbs, and moderate protein (1 to 1.5 g per kilogram of body weight) each day. We’ll look at Dom’s typical meals and day in a minute, but a few critical notes first: High protein and low fat doesn’t work. Your liver will convert excess amino acids into glucose and shut down ketogenesis. Fat as 70 to 85% of calories is required. This doesn’t mean you always have to eat rib eye steaks. A chicken breast by itself will kick you out of ketosis, but a chicken breast cut up into a green leafy salad with a lot of olive oil, feta cheese, and some Bulletproof Coffee (for example) can keep you in ketosis. One of the challenges of keto is the amount of fat one needs to consume to maintain it. Roughly 70 to 80% of your total calories need to come from fat. Rather than trying to incorporate fat bombs into all meals (one does get tired of fatty steak, eggs, and cheese over and over again), Dom will both drink fat between meals (e.g., coconut milk—not water—in coffee) and add in supplemental “ice cream,” detailed on page 29. Dom noticed that dairy can cause lipid profile issues (e.g., can spike LDL) and has started to minimize things like cream and cheese. I experienced the same. It’s easy to eat a disgusting amount of cheese to stay in keto. Consider coconut milk (Aroy-D Pure Coconut Milk) instead. Dom doesn’t worry about elevated LDL as long as other blood markers aren’t out of whack (high CRP, low HDL, etc.). From Dom: “The thing that I focus on most is triglycerides. If your triglycerides are elevated, that means your body is just not adapting to the ketogenic diet. Some people’s triglycerides are elevated even when their calories are restricted. That’s a sign that the ketogenic diet is not for you. . . . It’s not a one-size-fits-all diet.

toward specific underlying health conditions like diabetes, fatty liver, heart disease or cancer. This was particularly easy to create when we had the genetic data. This means the virus will not affect healthy individuals as much, but it will ravage those with underlying issues.

Supplements may hinder autophagy. When fasting for metabolic reasons (meaning insulin resistance–related conditions such as type 2 diabetes, obesity, PCOS, and nonalcoholic fatty liver disease), the effectiveness of supplements is questionable. Most vitamins are fat soluble, but if you’re not taking in fat they won’t be as effective. Probiotics are fine to continue taking while fasting.

Vitamin D3 boasts a strong safety profile, along with broad and deep evidence that links it to brain, metabolic, cardiovascular, muscle, bone, lung, and immune health. New and emerging research suggests that vitamin D supplements may also slow down our epigenetic/biological aging.29, 30 2. Omega-3 fish oil: Over the last thirty years or so, the typical Western diet has added more and more pro-inflammatory omega-6 polyunsaturated fatty acids versus anti-inflammatory omega-3 PUFAs. Over the same period, we’ve seen an associated rise in chronic inflammatory diseases, including obesity, cardiovascular disease, rheumatoid arthritis, and Alzheimer’s disease. 31 Rich in omega-3s, fish oil is another incredibly versatile nutraceutical tool with multi-pronged benefits from head to toe. By restoring a healthier PUFA ratio, it especially helps your brain and heart. Regular consumption of fatty fish like salmon has been linked to a lower risk of congestive heart failure, coronary heart disease, sudden cardiac death, and stroke.32 In an observational study, omega-3 fish oil supplementation was also associated with a slower biological clock.33 3. Magnesium deficiency affects more than 45 percent of the U.S. population. Supplements can help us maintain brain and cardiovascular health, normal blood pressure, and healthy blood sugar metabolism. They may also reduce inflammation and help activate our vitamin D. 4. Vitamin K1/K2 supports blood clotting, heart/ blood vessel health, and bone health.34 5. Choline supplements with brain bioavailability, such as CDP-Choline, citicoline, or alpha-GPC, can boost your body’s storehouse of the neurotransmitter acetylcholine and possibly support liver and brain function, while protecting it from age-related insults.35 6. Creatine: This one may surprise you, since it’s often associated with serious athletes and fitness buffs. But according to Dr. Lopez, it’s “a bona fide arrow in my longevity nutraceutical quiver for most individuals, and especially older adults.” As a coauthor of a 2017 paper by the International Society for Sports Nutrition, Dr. Lopez, along with contributors, stated that creatine not only enhances recovery, muscle mass, and strength in connection with exercise, but also protects against age-related muscle loss and various forms of brain injury.36 There’s even some evidence that creatine may boost our immune function and fat and carbohydrate metabolism. Generally well tolerated, creatine has a strong safety profile at a daily dose of three to five grams.37 7.

With regard to ALT liver values, the American College of Gastroenterology recently revised its guidelines to recommend clinical evaluation for liver disease in men with ALT above 33 and women with ALT above 25—significantly below the current “normal” ranges. Even that may not be low enough: a 2002 study that excluded people who already had fatty liver suggested upper limits of 30 for men, and 19 for women.

Garlic[43] : This amazing aromatic plant, the most powerful antioxidant known, has been used to treat and cure illnesses through the ages. Even Hippocrates recommended consuming large amounts of crushed garlic as a remedy. A study in China finds that consuming raw garlic regularly cuts the risk of lung cancer in half, and previous studies have suggested that it may also ward off other malignant tumors, such as colon cancer. It is best to let it sit for at least fifteen minutes after the pods have been crushed. This time is needed to release an enzyme (allicin) that produces antifungal and anti-cancer compounds. Alliates (garlic, onion, chives) and their cousins (leek, shallot) improve liver detoxification and therefore help protect our genes from mutations. I take it in three forms: tablet, powder and fresh. I use it in almost all my dishes and sauces, it is the anti-cancer food par excellence. Vegetables[44] : To avoid disease, nothing like a diet rich in raw and organic vegetables. The daily intake of vegetables would prevent cancers of the mouth, pharynx, esophagus, lung, stomach, breast, colon and rectum. I eat it abundantly; you could even say that it has become my staple food. I eat of course all the cabbage, garlic, onion, pepper but also asparagus, mushrooms, leek, cucumber, scallions (green onions), zucchini, celery, all salads, spinach, endives, pickles, radishes, green beans, parsley and aromatic herbs. At first, I ate cooked tomatoes but stopped because they contain too much sugar. Omega 3 :   Omega 3, in cancer, are anti-inflammatory. Omega 6 or linoleic acids (found in sunflower and peanut oils) are inflammatory. You must always have an omega 3 / omega 6 ratio favorable to omega 3. This is why I take capsules of this fatty acid in addition to eating sardines and anchovies[45]. An inflammatory environment is conducive to the formation and proliferation of cancer cells. To restore the balance, it is necessary to consume more foods rich in omega 3 such as fatty fish, rather small ones because of mercury pollution (sardines, anchovies, mackerel, herring), organic eggs or eggs from hens fed with flax, chia seeds and flax seeds, avocados, almonds, olive oil. These good fatty acids help in the prevention of several cancers including breast, prostate, mouth and skin.

Strategies to cook with less fat The following list provides some ideas on how to you can reduce the amount of fat you use in your cooking. Instead of frying, try grilling, baking, boiling, steaming as your preferred method of cooking to avoid adding those extra fats. Skim fat off the surface of soups and casseroles. Always remove the skin from poultry before cooking such as chicken.

Infact, the microscopic examination of a Fatty liver shows no difference whether it is from alcohol or diet cokes.

The other good news is that the human body is very adaptable. When it doesn’t get the calories it needs, it shifts its metabolism to buy us time to find those calories. The first thing it does is take the glycogen from our livers and convert it to glucose which goes into our bloodstream. When that glycogen is gone, the body starts using stored proteins and fat. Initially, these are broken down into glycerol, fatty acids, and amino acids, which lower the body’s need for glucose. The proteins that aren’t essential for survival will be used up first. If the body still isn’t getting the calories it needs, it shifts again. It starts relying on fat more, which it converts into ketones. And finally, when the fat reserves are gone, it begins cannibalizing the remaining protein. Muscles, our largest protein stores, are quickly depleted. That leaves proteins essential to cellular function. When the body begins using those, organ damage and failure follows.

Fatty Liver and Sluggish Liver Aloe vera: 2 or more inches of fresh gel (skin removed) daily Amla berry: 2 teaspoons daily Burdock root: 1 cup of tea daily Cardamom: 1 dropperful daily Chicory root: 1 cup of tea daily Dandelion root: 1 cup of tea daily Ginger: 1 cup of tea, 2 capsules, or freshly grated or juiced to taste daily Milk thistle: 1 dropperful daily Spirulina: 3 teaspoons daily Yellow dock: 1 cup of tea daily

In the procession of pieces, which Ikegawa changes based on his read of each guest, you find crunch and chew, fat and cartilage, soft, timid tenderness and bursts of outrageous savory intensity. He starts me with the breast, barely touched by the flame, pink in the center, green on top from a smear of wasabi, a single bite buries a lifetime of salmonella hysteria. A quick-cooked skewer of liver balances the soft, melting fattiness of foie with a gentle mineral bite. The tsukune, a string of one-bite orbs made from finely chopped thigh meat, arrives blistered on the outside, studded with pieces of cartilage that give the meatballs a magnificent chew. Chochin, the grilled uterus, comes with a proto-egg attached to the skewer like a rising sun. The combination of snappy meat and molten yolk is the stuff taste memories are made of.

In retrospect, I'm not sure why I considered unexpected beer a problem, but the place was smoky and not especially welcoming, and Iris was in the mood for tonkatsu but couldn't find any on the menu. She flipped through for a while and then said, "I want that." "Looks good to me," I said. It was some kind of chicken on a stick. When I ordered it, the waiter asked if we wanted shio or tare. This much I could understand. Shio is salt; tare is a rich, sweet sauce made from reduced soy sauce, mirin, and simmered chicken parts. It's a common choice in yakitori places; tare is the safe option, since anything tastes good with sweetened soy sauce. Salt is for when you really want to see what the grill master can do. Here we went with tare. Soon the waiter brought two skewers, each loaded up winy, glistening bites of chicken. We each took a bite and shared an astonished stare: this was the best chicken we'd ever tasted, and we had absolutely no idea what chicken part we were eating. Later we figured out that it was bonjiri (sometimes written bonchiri). In English, it's called chicken tail or, more memorably, the Pope's Nose, a fatty gland usually discarded when prepping a chicken for Western-style cooking. We ordered two more plates of the stuff. Yakitori is a beak-to-tail approach to chicken. OK, not literally beaks, but common choices at a yakitori place include thigh meat, breast meat, wings, heart, liver, and cartilage. The true test of a yakitori cook, I think, is chicken skin. To thread the skin onto skewers at the proper density and then grill it until juicy but neither overcooked (dry and crusty) or undercooked (unspeakable) requires serious skill.

The medical name for this condition is Non-Alcoholic Fatty Liver Disease (NAFLD) and it describes a range of conditions in which the liver tests are abnormal in people who drink little or no alcohol. It ranges from a mild condition in which excess fat is deposited in the liver causing slightly abnormal liver tests to a more serious condition in which the fat in the liver leads to inflammation, scarring and cirrhosis, which is irreversible liver damage. NAFLD is very common and may be found in up to 1 in 5 adults. Of those with NAFLD, about 1 in 4 will develop the more serious form leading to cirrhosis. This is a very slow process and may progress over years to liver failure. It is related to obesity and as in the metabolic syndrome (see previous question) insulin resistance is the underlying cause. There

a 2016 study linked another protein in wheat, amylase-trypsin inhibitors (ATIs), to inflammation in the lymph nodes, kidneys, spleen, and brain, and suggested that it could be linked to arthritis, asthma, and fatty liver disease, among other things.

So luscious! The dressing is extra-virgin olive oil and wine vinegar exquisitely melded with pureed pike liver. The rich, full-bodied flavor of the liver seeps into the tongue, gracefully underscoring the mild sweetness of the fatty meat. I feel like I'm drowning in a tidal wave of flavor and fragrance! Unbelievable! How many spices must he have mixed to-" "No. The spice used in this dish... ... is allspice alone." "What?!" "I thought Hayama's talent lay in the mixing of varied exotic spices to create the perfect fragrance." "No, his skill is in manipulating fragrance itself. He can do more than just add more spices into his recipes. In fact, this time he subtracted spices instead. In so doing, he accentuated the freshness and flavor of the in-season pike.

fatty acids are absorbed directly and do not pass through the liver before entering into the regular bloodstream.

All steroid hormones in vertebrates are built of cholesterol. The choice of cholesterol as the foundation for these hormones makes sense, because the body brims with it. Even if you never touch cholesterol-rich food such as eggs, oil, and meat, your liver continues to make cholesterol around the clock, and with reason. Cholesterol is an essential component of the plasma membrane, the fatty, protective coat surrounding every cell. At least half of the average cell’s membrane consists of cholesterol, much more than half in neurons. Without cholesterol, your cells would fall apart. Without cholesterol, new cells could not be manufactured. There would be no way of replacing the cells of the skin, gut, and immune system, which die by the millions each day. Cholesterol is the fat of the earth and the fat of the brain.

Baked or fried salmon, with sautéed chard, and cheese and macadamia nuts for dessert. 2 Bacon burgers with cheese and a salad. 3 Lamb stew meat sautéed in butter or ghee, topped with blue cheese, and a side of plain Greek yogurt with macadamia nuts. 4 Almond-flour coated chicken fried in butter or ghee, with sautéed-in-butter chard, and shredded Parmesan cheese. 5 Super Cobb salad with blue cheese or olive oil and vinegar dressing fortified with broccoli and extra bacon or other meat. 6 Scallops wrapped in bacon and fried in bacon grease, with sautéed broccolini, and soft-boiled eggs on the side. 7 Liver, onions, and bacon sautéed in bacon grease, with plain, full-fat Greek yogurt mixed with crumbled blue cheese on the side, macadamia nuts for dessert. 8 Village-style Greek salad of cucumbers, bell peppers, onions, feta cheese, olives, tomatoes, with sautéed chicken with the skin. 9 Omelet stuffed with Parmesan, red onions, sautéed mushrooms, with a few sheets of dried nori (seaweed). 10 Fatty wieners or bratwurst split lengthwise and fried in butter till they’re curly and their skins are crisp and blackish in the places that touch the pan most, with steamed sauerkraut and strong, grainy brown mustard. Yum.

Dr. Cabot’s Liver Healing Soup Recipe Serves 6 - 8 8 cups water miso and/or tamari to taste 3 tablespoons of cold pressed olive oil 2 sweet potatoes, chopped 3 tomatoes, chopped 2 carrots, chopped 2 leeks, washed and sliced 1 bunch spinach (fresh or frozen), chopped 2 stalks of celery (including the tops), chopped 2 large brown onions, chopped 1 inch (2.5cm) finely chopped and peeled ginger root 2 cloves garlic, minced (optional) 1 bunch sliced kale or beet greens 1 cup cooked beans or lentils Add small amounts of celery seed, turmeric, pepper and miso (or tamari) to taste optional added extra ingredients: 2 - 3 fresh artichoke hearts 2 cups shiitake mushrooms fresh or reconstituted sliced 1 whole reishi mushroom (remove when cooked) ¼ cup arame or wakame seaweed chopped Although these 4 ingredients are traditionally very good for the liver and the immune system, not everyone likes these things, so if they really do not appeal to you, leave some or all of them out. In a large saucepan add the oil and bring to a moderate to high heat. Add the celery (plus tops), ginger root, turmeric, tomato, potato, carrots, onions, celery seed and garlic and some pepper. Stir continuously so the vegetables do not stick to the bottom. When the vegetables begin to brown, carefully add the water with miso/tamari to taste. Bring to the boil. Reduce the heat to a simmer. Add the lentils/beans and stir. If using these, add the seaweed, mushrooms and artichoke hearts. Simmer for about 2 hours. Add the kale and beet greens 15 minutes before you serve. If present, remove the reishi mushrooms. Stir in the miso/tamari to taste. Serve alone or with a side salad and one slice crusty wholemeal bread.

But what is legality, if it is legal to torture a goose or a duck by putting it in a cage where it can’t move, shoving a tube down its throat, and force-feeding it to make its liver fatty in order to make foie gras for people to spread on crackers? The Migratory Bird Treaty Act of 1918 applies to crows because some of their populations migrate. But the treaty provides that a species under its auspices may be hunted under regulations preventing detrimental effects on the overall population if there is good cause. Crows are exempted from the act’s protection when they “harm livestock” by eating corn. So American crows, Corvus brachyrhynchos, are considered great for target shooting. There is no bag limit. There used to be a specific crow-hunting season, beginning in September in some states. But in my state of Maine you can now shoot crows in any number at any time, except on Sundays. Migratory woodpeckers, such as the northern flicker, in contrast, are as far as I know not fair game even when they are damaging a home. And I think that is fair and reasonable.

goose or a duck by putting it in a cage where it can’t move, shoving a tube down its throat, and force-feeding it to make its liver fatty in order to make foie gras for people to spread on crackers? The Migratory Bird Treaty Act of 1918 applies to crows because some of their populations migrate. But the treaty provides that a species under its auspices may be hunted under regulations preventing detrimental effects on the overall population if there is good cause. Crows are exempted from the act’s protection when they “harm livestock” by eating corn. So American crows, Corvus brachyrhynchos, are considered great for target shooting. There is no bag limit. There used to be a specific crow-hunting season, beginning in September in some states. But in my state of Maine you can now shoot crows in any number at any time, except on Sundays. Migratory woodpeckers, such as the northern flicker, in contrast, are as far as I know not fair game even when they are damaging a home. And I think that is fair and reasonable.

Organs are slippery. Livers are the worst. Alcoholics, especially, have fatty livers. Those things are as slick as greased piglets and get bobbled all the time in the autopsy suite.

overweight men and women.62 They found a significant reduction in liver inflammation in the real oatmeal group, but that may have been because they lost so much more weight than the controls (that is, the placebo-oatmeal eaters). Nearly 90 percent of the real-oatmeal-treated subjects had lost weight, compared with no weight loss, on average, among the control group. So it may be that the benefits of whole grains on liver function are indirect.63 A follow-up study in 2014 helped confirm the findings of a protective role for whole grains in nonalcoholic fatty liver patients in reducing the risk of liver inflammation. In this study, refined grain consumption was associated with increased risk of the disease.64 So lay off the Wonder Bread and stick to truly wonderful whole-grain foods, including oatmeal.

nonalcoholic fatty liver disease.83 The news is good. A 2013 review of the best studies to date found that people who drank the most coffee had half the risk of liver cancer compared to those who drank the least.84 A subsequent study found the consumption of four or more cups of coffee a day was associated with 92 percent lower risk among smokers dying from chronic liver disease.85 Of course, quitting smoking would have helped as well; smoking may multiply by as much as tenfold the odds of those with hepatitis C dying from

But what if you’re already infected with hepatitis C or are among the nearly one in three American adults89 with nonalcoholic fatty liver disease? Until relatively recently, no clinical trials had put coffee to the test. But in 2013, researchers published a study in which forty patients with chronic hepatitis C were placed into two groups: The first group consumed four cups of coffee daily for a month, while the second group drank no coffee at all. After

diets. The effects may take several months to appear if the animals are fed something closer to what humans in America actually consume—around 20 percent of the calories in their diet. Stop feeding them the sugar, in either case, and the fatty liver goes away, and with it the insulin resistance.

7 foods that Naturally cleanse your Liver This article lists the 7 best foods to eat to keep your liver healthy: 1. Garlic Garlic Garlic contains sulfur compounds that are essential for supporting the liver and activating liver enzymes that are answerable for flushing out toxins and waste from the body. Garlic additionally contains element, a very important mineral and nutrient that assists in detoxification and supports the ductless gland. 2. Walnuts These oddly-shaped balmy contain high levels of l-arginine, glutathione, and polyunsaturated fatty acid fatty acids, all of that facilitate to detoxify the liver and support poison elimination. Plus, they're nice for fighting inflammation and supporting the health of the brain. 3. Citrus Fruits Lemons, limes and grapefruits are all natural sources of water-soluble vitamin and contain several potent antioxidants. Like garlic, citrus fruits have the flexibility to spice up the assembly of liver detoxification enzymes. 4. Turmeric This unimaginable herb contains a large indefinite amount of antioxidants that facilitate to repair the liver cells, shield against cellular injury and assist in detoxification. Turmeric is especially smart at serving to the liver hospital ward from serious metals and assist in endocrine metabolism. Turmeric conjointly boosts the assembly of gall and improves the health of the bladder. You can create Associate in nursing array of delectable chuck victimisation turmeric, starting from pumpkin and turmeric soup to “golden ice.” 5. Broccoli Along with alternative genus Brassica vegetables, like Belgian capital sprouts, cabbage and cauliflower, broccoli contains sulfur compounds, similar to garlic, that facilitate to support the detoxification method and also the health of the liver. In fact, these fibrous veggies will facilitate flush out toxins from your gut, and that they contain compounds that facilitate support the liver in metabolising hormones. 6. Leafy Vegetables The bitterer, the better! Your liver loves bitter, therefore fill on blow ball, rapini, arugula, leaf mustard and chicory. These foliaceous greens contain varied cleansing compounds that neutralize serious metals, which might abate the liver’s ability to detoxify. Plus, they assist to stimulate digestive fluid flow. 7. Avocado This unimaginable fruit contains glutathione that may be a powerful inhibitor that helps to guard the liver from incoming waste and toxins. It conjointly assists the liver in eliminating these chemicals from your body and protects against cellular harm.

The transition from the fed state to the fasted state occurs in several stages:3 1.Feeding: During meals, insulin levels are raised. This allows glucose uptake by tissues such as the muscle or brain for direct use as energy. Excess glucose is stored as glycogen in the liver. 2.The post-absorptive phase (six to twenty-four hours after fasting starts): Insulin levels begin to fall. The breakdown of glycogen releases glucose for energy. Glycogen stores last for roughly twenty-four hours. 3.Gluconeogenesis (twenty-four hours to two days): The liver manufactures new glucose from amino acids and glycerol. In non-diabetic persons, glucose levels fall but stay within the normal range. 4.Ketosis (one to three days after fasting starts): The storage form of fat, triglycerides, is broken into the glycerol backbone and three fatty acid chains. Glycerol is used for gluconeogenesis. Fatty acids may be used directly for energy by many tissues in the body, but not the brain. Ketone bodies, capable of crossing the blood-brain barrier, are produced from fatty acids for use by the brain. Ketones can supply up to 75 percent of the energy used by the brain.4 The two major types of ketones produced are beta hydroxybutyrate and acetoacetate, which can increase more than seventy-fold during fasting.5 5.Protein conservation phase (after five days): High levels of growth hormone maintain muscle mass and lean tissues. The energy for maintenance of basal metabolism is almost entirely met by the use of free fatty acids and ketones. Increased norepinephrine (adrenalin) levels prevent the decrease in metabolic rate.

That’s good news,” Izumi says. “The other good news is that the human body is very adaptable. When it doesn’t get the calories it needs, it shifts its metabolism to buy us time to find those calories. The first thing it does is take the glycogen from our livers and convert it to glucose which goes into our bloodstream. When that glycogen is gone, the body starts using stored proteins and fat. Initially, these are broken down into glycerol, fatty acids, and amino acids, which lower the body’s need for glucose. The proteins that aren’t essential for survival will be used up first. If the body still isn’t getting the calories it needs, it shifts again. It starts relying on fat more, which it converts into ketones. And finally, when the fat reserves are gone, it begins cannibalizing the remaining protein. Muscles, our largest protein stores, are quickly depleted. That leaves proteins essential to cellular function. When the body begins using those, organ damage and failure follows. At this point, the immune system begins to severely degrade. Infectious diseases we might have fought off easily become deadly. Death from cardiac arrest is common at this stage. Most who live past those dangers die of one of two diseases: kwashiorkor and marasmus.

Liver Problems Treatment in Hyderabad | Dr. Kiran Peddi Liver problems which includes for treatment, Hepatitis A, Hepatitis B, Hepatitis C, Hepatitis D, Jaundice, Fatty Liver, Alcoholic Liver disease, Liver Cancer, Auto Immune Hepatitis, Gall bladder cancer, Primary sclerosing Cholangitis, Primary Biliary cirrhosis, Gall Stones.

Due to regular consumption of these processed foods, sugary drinks, Children are now being diagnosed with Obesity, Insulin resistance, Type-2 diabetes, Non-alcoholic fatty liver Disease (NAFLD). Yes, Children are now prone to chronic diseases in their early years of life, way before reaching their teenage/adulthood (<20).

Excessive consumption of fructose contributes to the development of fatty liver disease, kidney stones, and gout.

Lean meats: beef (except ribs and rib eye), veal, grilled or roasted without oil or fat, buffalo, and venison, except cuts used for braising or stewing Organ meats: kidneys, liver, and tongue All poultry, except duck and goose, but without the skin Lean pork All fish—fatty, lean, white, oily, raw or cooked All shellfish Low-fat ham, sliced low-fat chicken Eggs Nonfat dairy products

Dr. Gerber also is seeing improvement in patients with non-alcoholic fatty liver disease (NAFLD), psoriasis, and Crohn’s disease, who all “have done very well” on a ketogenic diet.

A number of studies have found that fructose: ■ inhibits our immune system, making it harder to fight off viruses and infections. ■ upsets the mineral balance in our bodies, causing deficiencies as well as interfering with mineral absorption. ■ messes with fertility. ■ speeds up the aging process. ■ has been connected with the development of cancers of the breast, ovaries, prostate, rectum, pancreas, lung, gallbladder and stomach. ■ is linked to dementia. ■ causes an acidic digestive tract, indigestion and malabsorption. ■ can cause a rapid rise in adrenaline, as well as hyperactivity, anxiety and a loss of concentration. SUGAR = POISON? The research is growing to show sugar is indeed poisoning us. Studies are proving sugar to be the biggest cause of fatty liver, which leads to insulin resistance. This then causes metabolic syndrome, which is now being seen as the biggest precursor to heart disease, diabetes and cancer.