Experimental Related Quotes

For whatever reason I was born into privilege; I've never known hunger, poverty, or despair. I have been blessed, blessed, blessed—relationally, emotionally, spiritually, and physically.

There are indeed many interesting parallels between David Bohm's work in physics and Karl Pribram's work in neurophysiology. After decades of intensive research and experimentation, this world-renown neuroscientist has concluded that only the presence of holographic principles at work in the brain can explain the otherwise puzzling and paradoxical observations relating to brain function. Pribram's revolutionary model of the brain and Bohm's theory of holomovement have far-reaching implications for our understanding of human consciousness that we have only begun to translate to the personal level.

There is a most profound and beautiful question associated with the observed coupling constant, e - the amplitude for a real electron to emit or absorb a real photon. It is a simple number that has been experimentally determined to be close to 0.08542455. (My physicist friends won't recognize this number, because they like to remember it as the inverse of its square: about 137.03597 with about an uncertainty of about 2 in the last decimal place. It has been a mystery ever since it was discovered more than fifty years ago, and all good theoretical physicists put this number up on their wall and worry about it.) Immediately you would like to know where this number for a coupling comes from: is it related to pi or perhaps to the base of natural logarithms? Nobody knows. It's one of the greatest damn mysteries of physics: a magic number that comes to us with no understanding by man. You might say the "hand of God" wrote that number, and "we don't know how He pushed his pencil." We know what kind of a dance to do experimentally to measure this number very accurately, but we don't know what kind of dance to do on the computer to make this number come out, without putting it in secretly!

The existence of both (electron and pebble) depends upon the context created by our thoughts, our language, our theories, and our interaction (experimentation) with our external world.

Einstein's theory, experimentally corroborated for the last hundred years, regardless of how outlandish and opposed to our prejudices (disguised as they are with the 'common sense' costume), is rational, consistent, and intelligible to the layperson - if s/he has the audacity of accepting the unfounded nature of those prejudices.

We are, in large part, a culture that expects its boys to initiate themselves into manhood. But holistic or even minimal initiation into manhood through relatively unguided self-experimentation is rare. Boys cannot become whole men without men and women making them into men.

Of course it would not occur to us to doubt the importance, experimentally demonstrated, of external sensory stimuli during sleep, but we have given this material the same place relative to the dream-wish as we have the remnants of thought left over from the work of the day. We do not need to dispute that the dream interprets the objective sensory stimulus as if it were an illusion; but where the authorities left the motive for this interpretation uncertain, we have put it in.

In other words, the more differentiated, relatively developed societies have cultivated a comparatively high tolerance for highly individualised ways of further developing the existing art canon; this facilitates experimentation and the breaching of stale conventions and can thus help to enrich the artistic pleasures available through seeing and hearing.

What made this project especially remarkable is that, among the many associations that are relevant to diet and disease, so many pointed to the same finding: people who ate the most animal-based foods got the most chronic disease. Even relatively small intakes of animal-based food were associated with adverse effects. People who ate the most plant-based foods were the healthiest and tended to avoid chronic disease. These results could not be ignored. From the initial experimental animal studies on animal protein effects to this massive human study on dietary patterns, the findings proved to be consistent. The health implications of consuming either animal or plant-based nutrients were remarkably different.

The society we live in today is just an experiment. Nobody has the answers. Nobody knows where it’s going, or why. We don’t even know where we would like it to go. There’s no grown-up out there, looking out for us. Nobody’s home. It’s just one big, glorious chaos engine; busy, busy spawning all manner of unimaginable creatures, existences, relations, exquisite beauties and excruciating tragedies. When you truly see this, an experimental attitude towards society suddenly seems much less reckless or disrespectful. It is the only appropriate stance.

Facts, and facts alone, are the foundation of science... When one devotes oneself to experimental research it is in order to augment the sum of known facts, or to discover their mutual relations.

[Fantasy] is a constructive aspect of the child's experimental exploration of reality, or his progressive relating of himself to reality, of his trial-and-error attempts to solve his reality problems.

There are two foundational pillars upon which modern physics rests. One is Albert Einstein's general relativity, which provides a theoretical framework for understanding the universe on the largest of scales: stars, galaxies, clusters of galaxies, and beyond to the immense expanse of the universe itself. The other is quantum mechanics, which provides a theoretical framework for understanding the universe on the smallest of scales: molecules, atoms, and all the way down to subatomic particles like electrons and quarks. Through years of research, physicists have experimentally confirmed to almost unimaginable accuracy virtually all predictions made by each of these theories. But these same theoretical tools inexorably lead to another disturbing conclusion: As they are currently formulated, general relativity and quantum mechanics cannot both be right.

The velocity of light is one of the most important of the fundamental constants of Nature. Its measurement by Foucault and Fizeau gave as the result a speed greater in air than in water, thus deciding in favor of the undulatory and against the corpuscular theory. Again, the comparison of the electrostatic and the electromagnetic units gives as an experimental result a value remarkably close to the velocity of light–a result which justified Maxwell in concluding that light is the propagation of an electromagnetic disturbance. Finally, the principle of relativity gives the velocity of light a still greater importance, since one of its fundamental postulates is the constancy of this velocity under all possible conditions.

People want to believe these research studies are about something simple that they can relate to like winning a contest. They don’t want to think about why a government would want to experiment on its citizens. They do it because they can, I said. Because you don’t see us as people.

It is the skill and ingenuity of the experimenter which show him phenomena which depend on a relatively narrow set of relatively easily realizable and reproducible conditions. If there were no phenomena which are independent of all but a manageably small set of conditions, physics would be impossible.

Rhine’s experiments confront us with the fact that there are events which are related to one another experimentally, and in this case meaningfully, without there being any possibility of proving that this relation is a causal one, since the “transmission” exhibits none of the known properties of energy.

We don't live in a world of perfect non-violent beauty. If we don't do the trials on animal specimens first, would you rather give yourself or a relative of yours up for experimentation! Some may say, why don't we avoid experimentation on live specimens all together - to them I say, modern medicine is not magic to work without errors - and hard and cruel as it may sound, a live animal specimen is expendable, but not a live human being. You may say, that's not fair - and indeed, it is in no way fair, but that's the reality. The only fairer alternative is to let humans suffer and die from diseases, like they used to, until about a few centuries ago.

On the one hand, it is said that the animals are so unlike us that they are not worthy of our consideration. On the other hand, vivisectors claim that animals are so like us that they are essential to research. In these conflicting statements we see a researcher's own confusion as to the genuine nature of his "subjects," and their nature in relation to this own.

The importance of experimental proof, on the other hand, does not mean that without new experimental data we cannot make advances. It is often said that science takes steps forward only when there is new experimental data. If this were true, we would have little hope of finding the theory of quantum gravity before measuring something new, but this is patently not the case. Which new data were available to Copernicus? None. He had the same data as Ptolemy. Which new data did Newton have? Almost none. His real ingredients were Kepler's laws and Galileo's results. What new data did Einstein have to discover general relativity? None. His ingredients were special relativity and Newton's theory. It simply isn't true that physics only advances when it is afforded new data.

Hello." Her mood deflated as if she'd been pricked with a pin. "Alan." "Shelby." She struggled not to be moved by the quiet,serious tone that should never have moved her.She liked men with a laugh in their voice. "Alan, this has to stop." "Does it? It hasn't even started." "Alan-" She tried to remember her decision to be firm. "I mean it. You have to stop sending me things. You're only wasting your time." "I have a bit to spare," he said mildly. "How was your week?" "Busy.Listen,I-" "I missed you." The simple statement threw the rest of her lecture into oblivion. "Alan, don't -" "Everyday," he continued. "Every night. Have you been to Boston, Shelby?" "Uh...yes," she managed, busy fighting off the weakness creeping into her. Helplessly she stared up at the balloons. How could she fight something so insubstantial it floated? "I'd like to take you there in the fall, when it smells of damp leaves and smoke." Shelby told herself her heart was not fluttering. "Alan, I didn't call to talk about Boston.Now,to put it in very simple terms,I want you to stop calling me, I want you to stop dropping by, and -" Her voice began to rise in frustration as she pictured him listening with that patient, serious smile and calm eyes. "I want you to stop sending me balloons and pigs and everything! Is that clear?" "Perfectly.Spend the day with me." Did the man ever stop being patient? She couldn't abide patient men. "For God's sake, Alan!" "We'll call it an experimental outing," he suggested in the same even tone. "Not a date." "No!" she said, barely choking back a laugh. Couldn't abide it, she tried to remember.She preferred the flashy, the freewheeling. "No,no,no!" "Not bureaucratic enough." His voice was so calm,so...so senatorial, she decided, she wanted to scream. But the scream bubbled perilously close to another laugh. "All right, let me think-a standard daytime expedition for furthering amiable relations between opposing clans." "You're trying to be charming again," Shelby muttered. "Am I succeeding?

He made imaginative leaps and discerned great principles through thought experiments rather than by methodical inductions based on experimental data. The theories that resulted were at times astonishing, mysterious, and counterintuitive, yet they contained notions that could capture the popular imagination: the relativity of space and time, E=mc2, the bending of light beams, and the warping of space. Adding

At some very low level, we all share certain fictions about time, and they testify to the continuity of what is called human nature, however conscious some, as against others, may become of the fictive quality of these fictions. It seems to follow that we shall learn more concerning the sense-making paradigms, relative to time, from experimental psychologists than from scientists or philosophers, and more from St. Augustine than from Kant or Einstein because St. Augustine studies time as the soul's necessary self-extension before and after the critical moment upon which he reflects. We shall learn more from Piaget, from studies of such disorders as déjà vu, eidetic imagery, the Korsakoff syndrome, than from the learned investigators of time's arrow, or, on the other hand, from the mythic archetypes. Let us take a very simple example, the ticking of a clock. We ask what it says: and we agree that it says tick-tock. By this fiction we humanize it, make it talk our language. Of course, it is we who provide the fictional difference between the two sounds; tick is our word for a physical beginning, tock our word for an end. We say they differ. What enables them to be different is a special kind of middle. We can perceive a duration only when it is organized. It can be shown by experiment that subjects who listen to rhythmic structures such as tick-tock, repeated identically, 'can reproduce the intervals within the structure accurately, but they cannot grasp spontaneously the interval between the rhythmic groups,' that is, between tock and tick, even when this remains constant. The first interval is organized and limited, the second not. According to Paul Fraisse the tock-tick gap is analogous to the role of the 'ground' in spatial perception; each is characterized by a lack of form, against which the illusory organizations of shape and rhythm are perceived in the spatial or temporal object. The fact that we call the second of the two related sounds tock is evidence that we use fictions to enable the end to confer organization and form on the temporal structure. The interval between the two sounds, between tick and tock is now charged with significant duration. The clock's tick-tock I take to be a model of what we call a plot, an organization that humanizes time by giving it form; and the interval between tock and tick represents purely successive, disorganized time of the sort that we need to humanize. Later I shall be asking whether, when tick-tock seems altogether too easily fictional, we do not produce plots containing a good deal of tock-tick; such a plot is that of Ulysses.

From Bacon, Diderot learned that science need not bow down before a Bible-based view of the world; it should be based on induction and experimentation, and, ideally, used to further humankind’s mastery of nature. Locke delivered two related concepts. The first was a theory of mind that rejected the long-standing belief that humans were born with innate ideas (and, therefore, with an inborn understanding of the divine). In Locke’s view, the mind is a blank slate at birth, and our understanding of the exterior world comes about solely through sensation and reflection. This entirely nonspiritual view of cognition set up a second critical lesson. Since, according to the English philosopher, true knowledge is limited to what we can learn through our senses, anyone involved in seeking out nature’s secrets must rely on observation and experiment — on a so-called empirical approach — and avoid building huge systems based on fantasy.

Then there occurred to me the 'glucklichste Gedanke meines Lebens,' the happiest thought of my life, in the following form. The gravitational field has only a relative existence in a way similar to the electric field generated by magnetoelectric induction. Because for an observer falling freely from the roof of a house there exists-at least in his immediate surroundings-no gravitational field [his italics]. Indeed, if the observer drops some bodies then these remain relative to him in a state of rest or of uniform motion, independent of their particular chemical or physical nature (in this consideration the air resistance is, of course, ignored). The observer therefore has the right to interpret his state as 'at rest.' Because of this idea, the uncommonly peculiar experimental law that in the gravitational field all bodies fall with the same acceleration attained at once a deep physical meaning. Namely, if there were to exist just one single object that falls in the gravitational field in a way different from all others, then with its help the observer could realize that he is ina gravitational field and is falling in it. If such an object does not exist, however-as experience has shown with great accuracy-then the observer lacks any objective means of perceiving himself as falling in a gravitational field. Rather he has the right to consider his state as one of rest and his environment as field-free relative to gravitation. The experimentally known matter independence of the acceleration of fall is therefore a powerful argument for the fact that the relativity postulate has to be extended to coordinate systems which, relative to each other, are in non-uniform motion.

The natural man receiveth not the things of the Spirit of God: for they are foolishness unto him. 1 Corinthians 2:14 It has pleased God to say many things which leave room for misunderstanding, and not to explain them. Often in the Bible there seem to be conflicting statements or statements that seem to violate the known facts of life, and it has pleased Him to leave them there. There are many scriptures we cannot clearly explain. Had we been writing, we would have put things far more plainly so that men should have before them all the doctrine in foolproof systematic order. But would they have had the life? The mighty eternal truths of God are half obscured in Scripture so that the natural man may not lay hold of them. God has hidden them from the wise to reveal them to babes, for they are spiritually discerned. His Word is not a study book. It is intended to meet us in the course of our day-to-day walk in the Spirit and to speak to us there. It is designed to give us knowledge that is experimental because related to life. If we are trying through systematic theology to know God, we are absolutely on the wrong road.

The most notorious story is the Trovan antibiotic study conducted by Pfizer in Kano, Nigeria, during a meningitis epidemic. An experimental new antibiotic was compared, in a randomised trial, with a low dose of a competing antibiotic that was known to be effective. Eleven children died, roughly the same number from each group. Crucially, the participants were apparently not informed about the experimental nature of the treatments, and moreover, they were not informed that a treatment known to be effective was available, immediately, from Médecins sans Frontières next door at the very same facility. Pfizer argued in court – successfully – that there was no international norm requiring it to get informed consent for a trial involving experimental drugs in Africa, so the cases relating to the trial should be heard in Nigeria only. That’s a chilling thing to hear a company claim about experimental drug trials, and it was knocked back in 2006 when the Nigerian Ministry of Health released its report on the trial. This stated that Pfizer had violated Nigerian law, the UN Convention on the Rights of the Child and the Declaration of Helsinki.

in experimental quantum mechanics we have run right up against what was previously perceived to be a purely philosophical barrier. The experiments are telling us that we can know nothing of reality-in-itself. We have to accept that the properties we ascribe to quantum particles like photons, such as energy, frequency, spin, polarization, position (‘here’ or ‘there’), are properties that have no meaning except in relation to a measuring device that allows them to be projected into our empirical reality of experience. We can no longer assume that the properties we measure necessarily reflect or represent the properties of the particles as they really are.

I think it's part of moral progress to be able to face things that once looked as if they weren't problems. I have that kind of feeling about our relation to animals... Abortion's a similar case-there are complicated moral issues. Feminist issues were a similar case. Slavery was a similar case. I mean, some of these things seem easy now, because we've solved them and there's a kind of shared consensus-but I think it's a very good thing that people are asking questions these days about, say, animal rights. I think there are serious questions there. Like, to what extent do we have a right to experiment on and torture animals? I mean, yes, you want to do animal experimentation for the prevention of diseases. But what's the balance, where's the trade-off?

Einstein further confused the issue in the last few years of his life by giving a series of statements on the subject to a physicist named Robert Shankland. At first he said he had read of Michelson-Morley only after 1905, then he said he had read about it in Lorentz’s book before 1905, and finally he added, “I guess I just took it for granted that it was true.”23 That final point is the most significant one because Einstein made it often. He simply took for granted, by the time he started working seriously on relativity, that there was no need to review all the ether-drift experiments because, based on his starting assumptions, all attempts to detect the ether were doomed to failure.24 For him, the significance of these experimental results was to reinforce what he already believed: that Galileo’s relativity principle applied to light waves.

Sexual conflict occurs when one mating partner has an opportunity to increase its fitness at a cost to the other partner. On a genetic level, most sexual conflicts are interlocus conflicts that mainly concern the outcome of male-female interactions about the mating rate, fertility efficiency, relative parental effort, remating behavior, and female reproductive rate. In sexually antagonistic evolution, a trait that affords advantage to one sex is disadvantageous to the other. An example is the sexual arms race that evolves when resistance in one sex drives the evolution of coercive traits in the other sex. Without the restrictions of natural selection, this process may lead to a runaway amplification of male and female traits. The coevolutionary arms races between adaptations in one sex and counteradaptations in the other sex can be made visible by experimentally arresting evolution in one sex.

know of nothing that is able, to the same degree as a kiss, to conjure up from what we believed to be something with one definite aspect, the hundred other things it may equally well be, since each is related to a no less valid perspective. In short, just as in Balbec Albertine had often seemed different to me, now—as if, by magically accelerating the speed of the changes of perspective and coloring a person offers us in the course of our various encounters, I had tried to contain them all within the space of a few seconds in order to re-create experimentally the phenomenon that diversifies a person’s individuality and to draw out separately, as from a slipcase, all the possibilities it contains—now what I saw, in the brief trajectory of my lips toward her cheek, was ten Albertines; because this one girl was like a many-headed goddess, the head I had seen last, when I tried to draw near, gave way to another.

A falsifiable theory is one that makes a specific prediction about what results are supposed to occur under a set of experimental conditions, so that the theory might be falsified by performing the experiment and comparing predicted to actual results. A theory or explanation that cannot be falsified falls outside the domain of science. For example, Freudian psychoanalysis, which does not make specific experimental predictions, is able to revise its theory to match any observations, in order to avoid rejecting the theory altogether. By this reckoning, Freudianism is a pseudoscience, a theory that purports to be scientific but is in fact immune to falsification. In contrast, for example, Einstein’s theory of relativity made predictions (like the bending of starlight around the sun) that were novel and specific, and provided opportunities to disprove the theory by direct experimental observation. [The folly of scientism]

The critical infrastructure of Indigenous worlds is, fundamentally, about responsibility and being a good relative. But our responsibilities do not happen only in the realm of political transformation. Caretaking, which we address in the introduction and in Part III, is the basis, too, for vibrant economies that must work fluidly with political structures to reinforce the world we seek to build beyond capitalism. We must thus have faith in our own forms of Indigenous political economy, the critical infrastructures that Huson speaks of so eloquently. We must rigorously study, theorize, enact, and experiment with these forms. While it covers ambitious terrain, The Red Deal at its base provides a program for study, theorization, action, and experimentation. But we must do the work. And the cold, hard truth is that we must not only be willing to do the work on a small scale whenever it suits us—in our own lives, in our families, or even in The Red Nation. We must be willing, as our fearless Wet’suwet’en relatives have done, to enforce these orders on a large scale. In conversation, our The Red Nation comrade Nick Estes stated, “I don’t want to just honor the treaties. I want to enforce them.” We can and should implement these programs in our own communities to alleviate suffering and protect what lands we are still able to caretake under colonial rule. To survive extinction, however, we must enforce Indigenous orders in and amongst those who have made it clear they will not stop their plunder until we are all dead. Settler and imperial nations, military superpowers, multinational corporations, and members of the ruling class are enemies of the Earth and the greatest danger to our future. How will we enforce Indigenous political, scientific, and economic orders to successfully prevent our mass ruin? This is the challenge we confront and pose in The Red Deal, and it is the challenge that all who take up The Red Deal must also confront.

Now to picture the mechanism of this process of construction and not merely its progressive extension, we must note that each level is characterized by a new co-ordination of the elements provided—already existing in the form of wholes, though of a lower order—by the processes of the previous level. The sensori-motor schema, the characteristic unit of the system of pre-symbolic intelligence, thus assimilates perceptual schemata and the schemata relating to learned action (these schemata of perception and habit being of the same lower order, since the first concerns the present state of the object and the second only elementary changes of state). The symbolic schema assimilates sensori-motor schemata with differentiation of function; imitative accommodation is extended into imaginal significants and assimilation determines the significates. The intuitive schema is both a co-ordination and a differentiation of imaginal schemata. The concrete operational schema is a grouping of intuitive schemata, which are promoted, by the very fact of their being grouped, to the rank of reversible operations. Finally, the formal schema is simply a system of second-degree operations, and therefore a grouping operating on concrete groupings. Each of the transitions from one of these levels to the next is therefore characterized both by a new co-ordination and by a differentiation of the systems constituting the unit of the preceding level. Now these successive differentiations, in their turn, throw light on the undifferentiated nature of the initial mechanisms, and thus we can conceive both of a genealogy of operational groupings as progressive differentiations, and of an explanation of the pre-operational levels as a failure to differentiate the processes involved. Thus, as we have seen (Chap. 4), sensori-motor intelligence arrives at a kind of empirical grouping of bodily movements, characterized psychologically by actions capable of reversals and detours, and geometrically by what Poincaré called the (experimental) group of displacement. But it goes without saying that, at this elementary level, which precedes all thought, we cannot regard this grouping as an operational system, since it is a system of responses actually effected; the fact is therefore that it is undifferentiated, the displacements in question being at the same time and in every case responses directed towards a goal serving some practical purpose. We might therefore say that at this level spatio-temporal, logico-arithmetical and practical (means and ends) groupings form a global whole and that, in the absence of differentiation, this complex system is incapable of constituting an operational mechanism. At the end of this period and at the beginning of representative thought, on the other hand, the appearance of the symbol makes possible the first form of differentiation: practical groupings (means and ends) on the one hand, and representation on the other. But this latter is still undifferentiated, logico-arithmetical operations not being distinguished from spatio-temporal operations. In fact, at the intuitive level there are no genuine classes or relations because both are still spatial collections as well as spatio-temporal relationships: hence their intuitive and pre-operational character. At 7–8 years, however, the appearance of operational groupings is characterized precisely by a clear differentiation between logico-arithmetical operations that have become independent (classes, relations and despatialized numbers) and spatio-temporal or infra-logical operations. Lastly, the level of formal operations marks a final differentiation between operations tied to real action and hypothetico-deductive operations concerning pure implications from propositions stated as postulates.

Before we conclude that human cognitive mechanisms are riddled with biases and errors of judgment, we need to ask which adaptive problems human cognitive mechanisms evolved to solve and what would be “sound judgment” or “successful reasoning” from an evolutionary perspective. If humans have trouble locating their cars by color at night in parking lots illuminated with sodium vapor lamps, we would not conclude that our visual system is riddled with errors. Our eyes were designed to perceive the color of objects under natural, not artificial, light (Shepard, 1992). Many of the research programs that have documented “biases” in judgment, it turns out, have used artificial, evolutionarily unprecedented experimental stimuli that are analogous to sodium vapor lamps. Many, for example, require subjects to make probability judgments based on a single event (Gigerenzer, 1991, 1998). “Reliable numerical statements about the probability of a single event were rare or nonexistent in the Pleistocene—a conclusion reinforced by the relative poverty of number terms in modern band level societies” (Tooby & Cosmides, 1998 p. 40). A specific woman cannot have a 35 percent chance of being pregnant; she either is pregnant or is not, so probabilities hardly make sense when applied to a single case.

Despite the advancements of systematic experimental pipelines, literature-curated protein-interaction data continue to be the primary data for investigation of focused biological mechanisms. Notwithstanding the variable quality of curated interactions available in public databases, the impact of inspection bias on the ability of literature maps to provide insightful information remains equivocal. The problems posed by inspection bias extend beyond mapping of protein interactions to the development of pharmacological agents and other aspects of modern biomedicine. Essentially the same 10% of the proteome is being investigated today as was being investigated before the announcement of completion of the reference genome sequence. One way forward, at least with regard to interactome mapping, is to continue the transition toward systematic and relatively unbiased experimental interactome mapping. With continued advancement of systematic protein-interaction mapping efforts, the expectation is that interactome 'deserts', the zones of the interactome space where biomedical knowledge researchers simply do not look for interactions owing to the lack of prior knowledge, might eventually become more populated. Efforts at mapping protein interactions will continue to be instrumental for furthering biomedical research.

Perhaps Einstein himself said it best when he said, “I have no special talents.… I am only passionately curious.” In fact, Einstein would confess that he had to struggle with mathematics in his youth. To one group of schoolchildren, he once confided, “No matter what difficulties you may have with mathematics, mine were greater.” So why was Einstein Einstein? First, Einstein spent most of his time thinking via “thought experiments.” He was a theoretical physicist, not an experimental one, so he was continually running sophisticated simulations of the future in his head. In other words, his laboratory was his mind. Second, he was known to spend up to ten years or more on a single thought experiment. From the age of sixteen to twenty-six, he focused on the problem of light and whether it was possible to outrace a light beam. This led to the birth of special relativity, which eventually revealed the secret of the stars and gave us the atomic bomb. From the age of twenty-six to thirty-six, he focused on a theory of gravity, which eventually gave us black holes and the big-bang theory of the universe. And then from the age of thirty-six to the end of his life, he tried to find a theory of everything to unify all of physics. Clearly, the ability to spend ten or more years on a single problem showed the tenacity with which he would simulate experiments in his head.

Einstein’s first public collision with this anti-Semitism came in the summer of 1920. A shady German nationalist named Paul Weyland, an engineer by training, had turned himself into a polemicist with political aspirations. He was an active member of a right-wing nationalistic political party that pledged, in its 1920 official program, to “diminish the dominant Jewish influence showing up increasingly in government and in public.”9 Weyland realized that Einstein, as a highly publicized Jew, had engendered resentment and jealousy. Likewise, his relativity theory was easy to turn into a target, because many people, including some scientists, were unnerved by the way it seemed to undermine absolutes and be built on abstract hypotheses rather than grounded in solid experiment. So Weyland published articles denouncing relativity as “a big hoax” and formed a ragtag (but mysteriously well-funded) organization grandly dubbed the Study Group of German Scientists for the Preservation of a Pure Science. Joining with Weyland was an experimental physicist of modest reputation named Ernst Gehrcke, who for years had been assailing relativity with more vehemence than comprehension. Their group lobbed a few personal attacks at Einstein and the “Jewish nature” of relativity theory, then called a series of meetings around Germany, including a large rally at Berlin’s Philharmonic Hall on August 24.

Once again, he was deducing a theory from principles and postulates, not trying to explain the empirical data that experimental physicists studying cathode rays had begun to gather about the relation of mass to the velocity of particles. Coupling Maxwell’s theory with the relativity theory, he began (not surprisingly) with a thought experiment. He calculated the properties of two light pulses emitted in opposite directions by a body at rest. He then calculated the properties of these light pulses when observed from a moving frame of reference. From this he came up with equations regarding the relationship between speed and mass. The result was an elegant conclusion: mass and energy are different manifestations of the same thing. There is a fundamental interchangeability between the two. As he put it in his paper, “The mass of a body is a measure of its energy content.” The formula he used to describe this relationship was also strikingly simple: “If a body emits the energy L in the form of radiation, its mass decreases by L/V 2.” Or, to express the same equation in a different manner: L=mV 2. Einstein used the letter L to represent energy until 1912, when he crossed it out in a manuscript and replaced it with the more common E. He also used V to represent the velocity of light, before changing to the more common c. So, using the letters that soon became standard, Einstein had come up with his memorable equation: E=mc2

A more complex way to understand this is the method used by Hermann Minkowski, Einstein’s former math teacher at the Zurich Polytechnic. Reflecting on Einstein’s work, Minkowski uttered the expression of amazement that every beleaguered student wants to elicit someday from condescending professors. “It came as a tremendous surprise, for in his student days Einstein had been a lazy dog,” Minkowski told physicist Max Born. “He never bothered about mathematics at all.”63 Minkowski decided to give a formal mathematical structure to the theory. His approach was the same one suggested by the time traveler on the first page of H. G. Wells’s great novel The Time Machine, published in 1895: “There are really four dimensions, three which we call the three planes of Space, and a fourth, Time.” Minkowski turned all events into mathematical coordinates in four dimensions, with time as the fourth dimension. This permitted transformations to occur, but the mathematical relationships between the events remained invariant. Minkowski dramatically announced his new mathematical approach in a lecture in 1908. “The views of space and time which I wish to lay before you have sprung from the soil of experimental physics, and therein lies their strength,” he said. “They are radical. Henceforth space by itself, and time by itself, are doomed to fade away into mere shadows, and only a kind of union of the two will preserve an independent reality.”64 Einstein, who was still not yet enamored of math, at one point described Minkowski’s work as “superfluous learnedness” and joked, “Since the mathematicians have grabbed hold of the theory of relativity, I myself no longer understand it.” But he in fact came to admire Minkowski’s handiwork and wrote a section about it in his popular 1916 book on relativity.

The theory of relativity is a beautiful example of the basic character of the modern development of theory. That is to say, the hypotheses from which one starts become ever more abstract and more remote from experience. But in return one comes closer to the preeminent goal of science, that of encompassing a maximum of empirical contents through logical deduction with a minimum of hypotheses or axioms. The intellectual path from the axioms to the empirical contents or to the testable consequences becomes, thereby, ever longer and more subtle. The theoretician is forced, ever more, to allow himself to be directed by purely mathematical, formal points of view in the search for theories, because the physical experience of the experimenter is not capable of leading us up to the regions of the highest abstraction. Tentative deduction takes the place of the predominantly inductive methods appropriate to the youthful state of science. Such a theoretical structure must be quite thoroughly elaborated in order for it to lead to consequences that can be compared with experience. It is certainly the case that here, as well, the empirical fact is the all-powerful judge. But its judgment can be handed down only on the basis of great and difficult intellectual effort that first bridges the wide space between the axioms and the testable consequences. The theorist must accomplish this Herculean task with the clear understanding that this effort may only be destined to prepare the way for a death sentence for his theory. One should not reproach the theorist who undertakes such a task by calling him a fantast; instead, one must allow him his fantasizing, since for him there is no other way to his goal whatsoever. Indeed, it is no planless fantasizing, but rather a search for the logically simplest possibilities and their consequences.

One of the earliest studies found that using an iPad—an electronic tablet enriched with blue LED light—for two hours prior to bed blocked the otherwise rising levels of melatonin by a significant 23 percent. A more recent report took the story several concerning steps further. Healthy adults lived for a two-week period in a tightly controlled laboratory environment. The two-week period was split in half, containing two different experimental arms that everyone passed through: (1) five nights of reading a book on an iPad for several hours before bed (no other iPad uses, such as email or Internet, were allowed), and (2) five nights of reading a printed paper book for several hours before bed, with the two conditions randomized in terms of which the participants experienced as first or second. Compared to reading a printed book, reading on an iPad suppressed melatonin release by over 50 percent at night. Indeed, iPad reading delayed the rise of melatonin by up to three hours, relative to the natural rise in these same individuals when reading a printed book. When reading on the iPad, their melatonin peak, and thus instruction to sleep, did not occur until the early-morning hours, rather than before midnight. Unsurprisingly, individuals took longer to fall asleep after iPad reading relative to print-copy reading. But did reading on the iPad actually change sleep quantity/quality above and beyond the timing of melatonin? It did, in three concerning ways. First, individuals lost significant amounts of REM sleep following iPad reading. Second, the research subjects felt less rested and sleepier throughout the day following iPad use at night. Third was a lingering aftereffect, with participants suffering a ninety-minute lag in their evening rising melatonin levels for several days after iPad use ceased—almost like a digital hangover effect. Using LED devices at night impacts our natural sleep rhythms, the quality of our sleep, and how alert we feel during the day.

Try opening it.” He was doing that as she spoke, gently twisting the acorn in its cup without any success. It didn’t unscrew, so he tried harder, and then tried to pull it, but that didn’t work either. “Try twisting the other way,” said Asta. “That would just do it up tighter,” he said, but he tried, and it worked. The thread was the opposite way. “I never seen that before,” said Malcolm. “Strange.” So neatly and finely made were the threads that he had to turn it a dozen times before the two parts fell open. There was a piece of paper inside, folded up as small as it could go: that very thin kind of paper that Bibles were printed on. Malcolm and Asta looked at each other. “This is someone else’s secret,” he said. “We ought not to read it.” He opened it all the same, very carefully so as not to tear the delicate paper, but it wasn’t delicate at all: it was tough. “Anyone might have found it,” said Asta. “He’s lucky it was us.” “Luckyish,” said Malcolm. “Anyway, he’s lucky he hadn’t got it on him when he was arrested.” Written on the paper in black ink with a very fine pen were the words: We would like you to turn your attention next to another matter. You will be aware that the existence of a Rusakov field implies the existence of a related particle, but so far such a particle has eluded us. When we try measuring one way, our substance evades it and seems to prefer another, but when we try a different way, we have no more success. A suggestion from Tokojima, although rejected out of hand by most official bodies, seems to us to hold some promise, and we would like you to inquire through the alethiometer about any connection you can discover between the Rusakov field and the phenomenon unofficially called Dust. We do not have to remind you of the danger should this research attract the attention of the other side, but please be aware that they are themselves beginning a major program of inquiry into this subject. Tread carefully. “What does it mean?” said Asta. “Something to do with a field. Like a magnetic field, I s’pose. They sound like experimental theologians.” “What d’you think they mean by ‘the other side’?” “The CCD. Bound to be, since it was them chasing the man.

To wit, researchers recruited a large group of college students for a seven-day study. The participants were assigned to one of three experimental conditions. On day 1, all the participants learned a novel, artificial grammar, rather like learning a new computer coding language or a new form of algebra. It was just the type of memory task that REM sleep is known to promote. Everyone learned the new material to a high degree of proficiency on that first day—around 90 percent accuracy. Then, a week later, the participants were tested to see how much of that information had been solidified by the six nights of intervening sleep. What distinguished the three groups was the type of sleep they had. In the first group—the control condition—participants were allowed to sleep naturally and fully for all intervening nights. In the second group, the experimenters got the students a little drunk just before bed on the first night after daytime learning. They loaded up the participants with two to three shots of vodka mixed with orange juice, standardizing the specific blood alcohol amount on the basis of gender and body weight. In the third group, they allowed the participants to sleep naturally on the first and even the second night after learning, and then got them similarly drunk before bed on night 3. Note that all three groups learned the material on day 1 while sober, and were tested while sober on day 7. This way, any difference in memory among the three groups could not be explained by the direct effects of alcohol on memory formation or later recall, but must be due to the disruption of the memory facilitation that occurred in between. On day 7, participants in the control condition remembered everything they had originally learned, even showing an enhancement of abstraction and retention of knowledge relative to initial levels of learning, just as we’d expect from good sleep. In contrast, those who had their sleep laced with alcohol on the first night after learning suffered what can conservatively be described as partial amnesia seven days later, forgetting more than 50 percent of all that original knowledge. This fits well with evidence we discussed earlier: that of the brain’s non-negotiable requirement for sleep the first night after learning for the purposes of memory processing. The real surprise came in the results of the third group of participants. Despite getting two full nights of natural sleep after initial learning, having their sleep doused with alcohol on the third night still resulted in almost the same degree of amnesia—40 percent of the knowledge they had worked so hard to establish on day 1 was forgotten.

Burbank's power of love, reported Hall, "greater than any other, was a subtle kind of nourishment that made everything grow better and bear fruit more abundantly. Burbank explained to me that in all his experimentation he took plants into his confidence, asked them to help, and assured them that he held their small lives in deepest regard and affection." Helen Keller, deaf and blind, after a visit to Burbank, wrote in Out­ look for the Blind: "He has the rarest of gifts, the receptive spirit of a child. When plants talk to him, he listens. Only a wise child can understand the language of flowers and trees." Her observation was particularly apt since all his life Burbank loved children. In his essay "Training of the Human Plant," later published as a book, he an­ticipated the more humane attitudes of a later day and shocked authori­tarian parents by saying, "It is more important for a child to have a good nervous system than to try to 'force' it along the line of book knowledge at the expense of its spontaneity, its play. A child should learn through a medium of pleasure, not of pain. Most of the things that are really useful in later life come to the children through play and through association with nature." Burbank, like other geniuses, realized that his successes came from having conserved the exuberance of a small boy and his wonder for everything around him. He told one of his biographers: 'Tm almost seventy-seven, and I can still go over a gate or run a foot race or kick the chandelier. That's because my body is no older than my mind-and my mind is adolescent. It has never grown up and I hope it never will." It was this quality which so puzzled the dour scientists who looked askance at his power of creation and bedeviled audiences who expected him to be explicit as to how he produced so many horticultural wonders. Most of them were as disappointed as the members of the American Pomological Society, gathered to hear Burbank tell "all" during a lecture entitled "How to Produce New Fruits and Flowers," who sat agape as they heard him say: In pursuing the study of any of the universal and everlasting laws of nature, whether relating to the life, growth, structure and movements of a giant planet, the tiniest plant or of the psychological movements of the human brain, some conditions are necessary before we can become one of nature's interpreters or the creator of any valuable work for the world. Preconceived notions, dogmas and all personal prejudice and bias must be laid aside. Listen patiently, quietly and reverently to the lessons, one by one, which Mother Nature has to teach, shedding light on that which was before a mystery, so that all who will, may see and know. She conveys her truths only to those who are passive and receptive. Accepting these truths as suggested, wherever they may lead, then we have the whole universe in harmony with us. At last man has found a solid foundation for science, having discovered that he is part of a universe which is eternally unstable in form, eternally immutable in substance.

Yoel Goldenberg makes exhibitions, photographs, models and media craftsmanship. His works are an examination of ideas, for example, validness and objectivity by utilizing an exhaustive methodology and semi exploratory exactness and by referencing documentaries, 'actuality fiction' and prominent experimental reciprocals. Yoel Goldenberg as of now lives and works in Brooklyn. By challenging the division between the domain of memory and the domain of experience, Goldenberg formalizes the circumstantial and underlines the procedure of synthesis that is behind the apparently arbitrary works. The manners of thinking, which are probably private, profoundly subjective and unfiltered in their references to dream universes, are much of the time uncovered as collections. His practice gives a valuable arrangement of metaphorical instruments for moving with a pseudo-moderate approach in the realm of execution: these fastidiously arranged works reverberate and resound with pictures winnowed from the fantastical domain of creative energy. By trying different things with aleatoric procedures, Yoel Goldenberg makes work in which an interest with the clarity of substance and an uncompromising demeanor towards calculated and insignificant workmanship can be found. The work is detached and deliberate and a cool and unbiased symbolism is utilized. His works are highlighting unplanned, unintentional and sudden associations which make it conceivable to overhaul craftsmanship history and, far and away superior, to supplement it. Consolidating random viewpoints lead to astounding analogies. With a theoretical methodology, he ponders the firmly related subjects of file and memory. This regularly brings about an examination of both the human requirement for "definitive" stories and the inquiry whether tales "fictionalize" history. His gathered, changed and own exhibitions are being faced as stylishly versatile, specifically interrelated material for memory and projection. The conceivable appears to be genuine and reality exists, yet it has numerous countenances, as Hanna Arendt refers to from Franz Kafka. By exploring dialect on a meta-level, he tries to approach a wide size of subjects in a multi-layered route, likes to include the viewer in a way that is here and there physical and has faith in the thought of capacity taking after structure in a work. Goldenberg’s works are straightforwardly a reaction to the encompassing environment and uses regular encounters from the craftsman as a beginning stage. Regularly these are confined occasions that would go unnoticed in their unique connection. By utilizing a regularly developing file of discovered archives to make self-ruling works of art, he retains the convention of recognition workmanship into every day hone. This individual subsequent and recovery of a past custom is vital as a demonstration of reflection. Yoel’s works concentrate on the powerlessness of correspondence which is utilized to picture reality, the endeavor of dialog, the disharmony in the middle of structure and content and the dysfunctions of dialect. To put it plainly, the absence of clear references is key components in the work. With an unobtrusive moderate methodology, he tries to handle dialect. Changed into craftsmanship, dialect turns into an adornment. Right then and there, loads of ambiguities and indistinctnesses, which are intrinsic to the sensation, rise up to the top

ESTABLISH STABLE ANCHORS OF ATTENTION Mindfulness meditation typically involves something known as an anchor of attention—a neutral reference point that helps support mental stability. An anchor might be the sensation of our breath coming in and out of the nostrils, or the rising and falling of our abdomen. When we become lost in thought during practice, we can return to our anchor, fixing our attention on the stimuli we’ve chosen. But anchors can also intensify trauma. The breath, for instance, is far from neutral for many survivors. It’s an area of the body that can hold tension related to a trauma and connect to overwhelming, life-threatening events. When Dylan paid attention to the rising and falling of his abdomen, he would be swamped with memories of mocking faces while walking down the hallway. Other times, feeling a constriction of his breath in the chest echoed a feeling of immobility, which was a traumatic reminder. For Dylan, the breath simply wasn’t a neutral anchor. As a remedy, we can encourage survivors to establish stabilizing anchors of attention. This means finding a focus of attention that supports one’s window of tolerance—creating stability in the nervous system as opposed to dysregulation. Each person’s anchor will vary: for some, it could be the sensations of their hands resting on their thighs, or their buttocks on the cushion. Other stabilizing anchors might include another sense altogether, such as hearing or sight. When Dylan and I worked together, it took a while until he could find a part of his body that didn’t make him more agitated. He eventually found that the sense of hearing was a neutral anchor of attention. At my office, he’d listen for the sound of the birds or the traffic outside, which he found to be stabilizing. “It’s subtle,” he said to me, opening his eyes and rubbing the back of his neck with his hand. “But it is a lot less charged. I’m not getting riled up the same way, which is a huge relief.” In sessions together, Dylan’s anchor was a spot he’d rest his attention on at the beginning of a session or a place to return to if he felt overwhelmed. If he practiced meditation at home—I’d recommended short periods if he could stay in his window of tolerance—he used hearing as an anchor, or “home base” as he called it. “I finally feel like I can access a kind of refuge,” he said quietly, placing his hand on his belly. “My body hasn’t felt safe in so long. It’s a relief to finally feel like I’m learning how to be in here.” Anchors of attention you can offer students and clients practicing mindfulness—besides the sensation of the breath in the abdomen or nostrils—include different physical sensations (feet, buttocks, back, hands) and other senses (seeing, smelling, hearing). One client of mine had a soft blanket that she would touch slowly as an anchor. Another used a candle. For some, walking meditation is a great way to develop more stable anchors of attention, such as the feeling of one’s feet on the ground—whatever supports stability and one’s window of tolerance. Experimentation is key. Using subtler anchors does come with benefits and drawbacks. One advantage to working with the breath is that it is dynamic and tends to hold our attention more easily. When we work with a sense that’s less tactile—hearing, for instance—we may be more prone to drifting off into distraction. The more tangible the anchor, the easier it is to return to it when attention wanders.

Fortunately, 5-htp is relatively cheap and with few side-effects, so there is rarely little to lose by trying it out. I usually recommend starting on 100mg a day (50mg after lunch and 50mg before bed), before slowly moving up to 200mg a day. The optimum dosage for 5-htp is also unpredictable, so some experimentation may be required to get the dose correct.

How is regeneration of the spinal cord in the salamander related to its initial development ? There is now evidence that in the salamander, the steps of progenitor cell-patterning and controlled neurogenesis that naturally regenerate a severed tail largely recapitulate the steps followed during early embryonic development to initially build the central nervous system. For example, ependymal cells are descendants of radial glial cells retained from the earliest developmental stages in regenerating vertebrates. The ependymal tube that gives rise to regenerated spinal cord following salamander tail amputation is very similar in appearance to the early structure of the neural tube of developing amniotes. But how does that recapitulation occur ? By using a transgenic axolotl that expresses green fluorescent proteins (GFPs), they further examined the regenerated spinal cord by replacing a segment of the spinal cord from a typical animal with a piece of the spinal cord from a GFP-expressing animal - that is, one with green fluorescent cells. They found that the implanted cells in the experimental animals regenerated a green spinal cord ! Thus, regeneration may be a more neural stem-cell like, or pluripotent, state as a response to injury.

I walked out onto the stage and I started telling the tale of the “Untold Story of the Origin of Zombies.” And it went like this: Where do Zombies come from? Not many people know. But after some extensive investigative Zombie journalism, we’ve discovered the truth. It all began when the human government decided that they wanted to create stronger soldiers. They had lost too many battles, and now they wanted to win every war that they fought. So they approached some soldiers in their army to join a special secret project. The only requirement was that the soldiers they chose had no living relatives. This way, no one could claim their bodies in case something went wrong. So, they exposed these soldiers to an experimental virus to enhance their abilities and make them into super soldiers. The experiment seemed to be working. But then, something terrible happened... The soldiers went crazy, and they were horribly disfigured. Ultimately, the experiment claimed their lives. But, when the soldiers were being prepared for burial, they suddenly came to life. They were not only walking, but they had enhanced strength, enhanced sense of smell and enhanced hearing. They attacked the soldiers in charge of burying them. And the recently bitten soldiers also transformed into the living dead. Before long, the entire army base was contaminated with the virus. Once everyone in the base was exposed, the virus mutated and the soldiers began having an overwhelming craving for something warm and mushy. They longed for brains! Soon, the army of the living dead found their way to the next unsuspecting town in search of brains. They attacked that town, biting anything that moved both human and animal. Soon that town was overrun. The virus spread from town to town, and city to city, until the entire world was contaminated. It was the first Zombie Apocalypse. After hundreds of years had passed, the Zombies started to evolve and began developing intelligent thoughts. They began forming villages, and then towns, and then entire cities of Zombies were created. The Zombies made great advances in health and science, and became highly advanced technologically. But, eventually the Zombies’ appetite for brains and warm flesh gave way to an even greater craving... The craving for CAKE! Their overwhelming desire for cake resulted in an explosive rise in the baking industry. Cake shops began springing up on every corner of every Zombie city street. They just couldn’t get enough! The human race began growing again, too. Human villages of farmers and miners began springing up. And because the Zombies were a peaceful race, they coexisted with the humans by staying away from them. But soon, the Zombie’s resources began to become scarce, especially the cake. So Zombies began scaring villagers in order to get the supplies they needed, especially the highly valued resource of cake. Now Zombies send their kids to Scare School to train their children from a very young age. They train them on how to effectively scare humans in order to get their needed supplies, especially cake. And so it has been until today. Thank you.

Cognitive scientists recognize two types of rationality: instrumental and epistemic. The simplest definition of instrumental rationality-the one that emphasizes most that it is grounded in the practical world-is: Behaving in the world so that you get exactly what you most want, given the resources (physical and mental) available to you. Somewhat more technically, we could characterize instrumental rationality as the optimization of the individual's goal fulfillment. Economists and cognitive scientists have refined the notion of optimization of goal fulfillment into the technical notion of expected utility. The model of rational judgment used by decision scientists is one in which a person chooses options based on which option has the largest expected utility.' One discovery of modern decision science is that if people's preferences follow certain patterns (the so-called axioms of choice) then they are behaving as if they are maximizing utility-they are acting to get what they most want. This is what makes people's degrees of rationality measurable by the experimental methods of cognitive science. The deviation from the optimal choice pattern is an (inverse) measure of the degree of rationality. The other aspect of rationality studied by cognitive scientists is termed epistemic rationality. This aspect of rationality concerns how well beliefs map onto the actual structure of the world.' The two types of rationality are related. Importantly, a critical aspect of beliefs that enter into instrumental calculations (that is, tacit calculations) is the probabilities of states of affairs in the world.

While this signifier can be difficult to pin down with precision, it can clearly be heard in the records of Duane Eddy and many other guitarists of the period. It usually involves a relatively nondistorted electric guitar timbre articulated with a strong attack and a melody played on the lower strings. Reverberation is ubiquitous, and almost equally common were echo, amplifier tremolo, and use of the guitar’s vibrato bar. This overall guitar sound is often called a Fender sound, but that is a bit misleading, since Gretsch guitars were equally specialized for the purpose, and many other brands were also used. What makes the twang guitar interesting in topical terms is that it not only signified the western topic but also was key to a linked set of genres that intersect one another in complex ways: western, spy, and surf. Because these were all signified by overlapping musical features and in turn resemble one another in some of their broader connotations, we could speak of a twang guitar continuum: a range of topics that coalesced only shortly before psychedelia and were cognate with it in a variety of ways. Philip Tagg and Bob Clarida point out that the twang guitar, often in a minor mode with a flat seventh, was a common factor between spaghetti western and Bond/spy scores in the late 1950s and early 1960s. I would add surf guitar to the list, with its sonic experimentation and general relationship to fun, escape, and exoticism: “[The twang guitar] probably owes some of its immediate success as a spy sound to its similarity with various pre-rock ‘Viennese intrigue’ sounds like Anton Karas’s Third Man zither licks (1949). But in the 1962–64 period that produced The Virginian (1962), Dr. No (1963) and Leone’s A Fistful of Dollars (1964), steely Fender guitar was well on its way to becoming an all-purpose excitement/adventure timbre” (Tagg and Clarida 2003, 367).

Singh then experimented on a vast number of species, such as com­ mon asters, petunias, cosmos, and white spider lilies, along with such economic plants as onions, sesame, radishes, sweet potatoes, and tapioca. Each of these species Singh entertained for several weeks just before sunrise with more than half a dozen separate ragas, one per experiment, played on the flute, violin, harmonium, and veena; the music lasted a half hour daily, scaled at a high pitch, with frequencies between one hundred and six hundred cycles per second. From all this experimenta­tion Singh was able to state, in the magazine of the Bihar Agricultural College at Sabour, that he had "proven beyond any shadow of doubt that harmonic sound waves affect the growth, flowering, fruiting, and seed-yields of plants.

Leor Zmigrod, Peter Jason Rentfrow, and Trevor W. Robbins, “The Partisan Mind: Is Extreme Political Partisanship Related to Cognitive Inflexibility?” Journal of Experimental Psychology: General 149, no. 3.

Yet as we saw subjects treat contribution and punishment differently. After the initial rounds in the standard public goods without punishment game, experimental subjects decline to contribute altruistically but once punishment is permitted they avidly engage in the altruistic activity of punishing low contributors. Part of the reason for the difference is that people have an intrinsic motivation to punish shirkers, not simply an instrumental desire to alter their behavior or to affect the distribution of payoffs to either reduce unfairness or enhance one’s own relative payoffs.

We may still insist that space, although mainly emptiness, is completely “contaminated” by all the forces in the Universe—particles, waves, and so on. Still, based on this deduction or inference, we cannot prove that what is curved is space since nothing remains nothing and cannot be transformed into something based on the laws of physics. If the Nothing does not convert into something, the curvature of space is impossible. To prove the curvature of nothing (space), we must prove that nothing can transform itself into something based on the laws of physics. Suppose we further insist that this is only a problem of linguistics and philosophy and not physics since we stated that space is how we define it and not as it is. This reasoning would be insufficient because we must first prove that actual space is what it is and not what we say it is to fit our arguments. There can be no answers to the most critical questions of contemporary science, physics, philosophy, and even religions if we are not as precise as possible, linguistically, experimentally, or in any other way. These questions appear to be self-evident, self-explanatory truths and axioms, yet they are neither self-evident nor clear and precise to reflect the actual underlying reality. If we are not as precise as possible, we create theories and paradigms presented as facts, although the starting premises are undefined and unanswered. However, if we do not answer the starting causes and premises, we cannot adequately describe the laws of nature, nor can we understand them. Regardless of how sure we are about space and the curvature of space, we still cannot claim we are correct without describing the nature of nothing. Without the Nothing, there can be no space. There will be an immediate argument, though, that the Nothing has no nature and, therefore, there is nothing to describe. The answer is that its passivity and lack of properties are its most potent “property” because they enable creation and existence. Without the Nothing or void, there is no creation and no existence. We converted nothing into something by our thoughts and language, using deduction or inference, and concluded that space is the consequence of this thought process, not the actual process. We applied our definite language to our indefinite “understanding,” ideas, or reasoning to prove the “fact.” However, the fact is or is not, regardless of our ideas, language, or reasoning. We must use the opposite and apply language to the facts rather than our understanding. Our understanding is limited, and facts are impersonal and independent of our knowledge. We cannot falsify the language to fit and understand the facts better. We cannot change facts or affect them with our ideas, but facts are verifiable up to a point. There are facts beyond the verifiable point by humans since human beings are limited. Still, language is verifiable, and our theories are both falsifiable and verifiable to a large extent.

nutritional supplement worth considering is 5-HTP (5-hydroxytryptophan). It has been shown to be highly effective in moderating many behavior problems, including aggression, with far fewer or less problematic side effects than the heavy-duty prescription medications. It is surprising that veterinarians are not more familiar with this supplement, and that they do not take greater advantage of it, given its effectiveness, its relatively low cost and that it works as soon as it is taken (unlike many medications, which can take weeks to build up an effect). It should not be used in conjunction with medications that affect serotonin activity. The correct dosage is determined experimentally. If the dose is slightly high, the dog may be initially nauseous. If the dose is too low, no effects will be achieved. The dose used at Tufts University School of Veterinary Medicine for addressing aggression is 2 mg/kg, administered orally every 12 hours. If 5-HTP is used, you should watch for signs of serotonin syndrome (caused by an excess of serotonin activity in the brain). These include confusion/disorientation, agitation/irritability, low responsiveness/coma, anxiety, hypomania (elevated mood and increased activity), lethargy and seizures (Sorenson, 2002). You should also be on the lookout for these signs with the use of medications that influence serotonin activity.

We have to deal with rather than anesthetizing tension with TV or video games. It’s easier to bypass relational snags with a convenient distraction, forfeiting the chance to improve problem solving and listening skills. I don’t want my kids to be more comfortable interacting with a computer screen than a human being. We stay the course until we’ve resolved an issue, not allowing “Phineas & Ferb” to fill the space instead. This is harder and requires more time, but my kids will marry people and have bosses and children. Learning healthy relational skills is now or never.

But if ncRNAs are so important for cellular function, surely we would expect to find that sometimes diseases are caused by problems with them. Shouldn’t there be lots of examples where defects in production or expression of ncRNAs lead to clinical disorders, aside from the imprinting or X inactivation conditions? Well, yes and no. Because these ncRNAs are predominantly regulatory molecules, acting in networks that are rich in compensatory mechanisms, defects may only have relatively subtle impacts. The problem this creates experimentally is that most genetic screens are good at detecting the major phenotypes caused by mutations in proteins, but may not be so useful for more subtle effects.

Beyond One-Way ANOVA The approach described in the preceding section is called one-way ANOVA. This scenario is easily generalized to accommodate more than one independent variable. These independent variables are either discrete (called factors) or continuous (called covariates). These approaches are called n-way ANOVA or ANCOVA (the “C” indicates the presence of covariates). Two way ANOVA, for example, allows for testing of the effect of two different independent variables on the dependent variable, as well as the interaction of these two independent variables. An interaction effect between two variables describes the way that variables “work together” to have an effect on the dependent variable. This is perhaps best illustrated by an example. Suppose that an analyst wants to know whether the number of health care information workshops attended, as well as a person’s education, are associated with healthy lifestyle behaviors. Although we can surely theorize how attending health care information workshops and a person’s education can each affect an individual’s healthy lifestyle behaviors, it is also easy to see that the level of education can affect a person’s propensity for attending health care information workshops, as well. Hence, an interaction effect could also exist between these two independent variables (factors). The effects of each independent variable on the dependent variable are called main effects (as distinct from interaction effects). To continue the earlier example, suppose that in addition to population, an analyst also wants to consider a measure of the watershed’s preexisting condition, such as the number of plant and animal species at risk in the watershed. Two-way ANOVA produces the results shown in Table 13.4, using the transformed variable mentioned earlier. The first row, labeled “model,” refers to the combined effects of all main and interaction effects in the model on the dependent variable. This is the global F-test. The “model” row shows that the two main effects and the single interaction effect, when considered together, are significantly associated with changes in the dependent variable (p < .000). However, the results also show a reduced significance level of “population” (now, p = .064), which seems related to the interaction effect (p = .076). Although neither effect is significant at conventional levels, the results do suggest that an interaction effect is present between population and watershed condition (of which the number of at-risk species is an indicator) on watershed wetland loss. Post-hoc tests are only provided separately for each of the independent variables (factors), and the results show the same homogeneous grouping for both of the independent variables. Table 13.4 Two-Way ANOVA Results As we noted earlier, ANOVA is a family of statistical techniques that allow for a broad range of rather complex experimental designs. Complete coverage of these techniques is well beyond the scope of this book, but in general, many of these techniques aim to discern the effect of variables in the presence of other (control) variables. ANOVA is but one approach for addressing control variables. A far more common approach in public policy, economics, political science, and public administration (as well as in many others fields) is multiple regression (see Chapter 15). Many analysts feel that ANOVA and regression are largely equivalent. Historically, the preference for ANOVA stems from its uses in medical and agricultural research, with applications in education and psychology. Finally, the ANOVA approach can be generalized to allow for testing on two or more dependent variables. This approach is called multiple analysis of variance, or MANOVA. Regression-based analysis can also be used for dealing with multiple dependent variables, as mentioned in Chapter 17.

usually does not present much of a problem. Some analysts use t-tests with ordinal rather than continuous data for the testing variable. This approach is theoretically controversial because the distances among ordinal categories are undefined. This situation is avoided easily by using nonparametric alternatives (discussed later in this chapter). Also, when the grouping variable is not dichotomous, analysts need to make it so in order to perform a t-test. Many statistical software packages allow dichotomous variables to be created from other types of variables, such as by grouping or recoding ordinal or continuous variables. The second assumption is that the variances of the two distributions are equal. This is called homogeneity of variances. The use of pooled variances in the earlier formula is justified only when the variances of the two groups are equal. When variances are unequal (called heterogeneity of variances), revised formulas are used to calculate t-test test statistics and degrees of freedom.7 The difference between homogeneity and heterogeneity is shown graphically in Figure 12.2. Although we needn’t be concerned with the precise differences in these calculation methods, all t-tests first test whether variances are equal in order to know which t-test test statistic is to be used for subsequent hypothesis testing. Thus, every t-test involves a (somewhat tricky) two-step procedure. A common test for the equality of variances is the Levene’s test. The null hypothesis of this test is that variances are equal. Many statistical software programs provide the Levene’s test along with the t-test, so that users know which t-test to use—the t-test for equal variances or that for unequal variances. The Levene’s test is performed first, so that the correct t-test can be chosen. Figure 12.2 Equal and Unequal Variances The term robust is used, generally, to describe the extent to which test conclusions are unaffected by departures from test assumptions. T-tests are relatively robust for (hence, unaffected by) departures from assumptions of homogeneity and normality (see below) when groups are of approximately equal size. When groups are of about equal size, test conclusions about any difference between their means will be unaffected by heterogeneity. The third assumption is that observations are independent. (Quasi-) experimental research designs violate this assumption, as discussed in Chapter 11. The formula for the t-test test statistic, then, is modified to test whether the difference between before and after measurements is zero. This is called a paired t-test, which is discussed later in this chapter. The fourth assumption is that the distributions are normally distributed. Although normality is an important test assumption, a key reason for the popularity of the t-test is that t-test conclusions often are robust against considerable violations of normality assumptions that are not caused by highly skewed distributions. We provide some detail about tests for normality and how to address departures thereof. Remember, when nonnormality cannot be resolved adequately, analysts consider nonparametric alternatives to the t-test, discussed at the end of this chapter. Box 12.1 provides a bit more discussion about the reason for this assumption. A combination of visual inspection and statistical tests is always used to determine the normality of variables. Two tests of normality are the Kolmogorov-Smirnov test (also known as the K-S test) for samples with more than 50 observations and the Shapiro-Wilk test for samples with up to 50 observations. The null hypothesis of

Thus arises the second tendency, which consists in regarding logical and mathematical relations as irreducible, and in making an analysis of the higher intellectual functions depend on an analysis of them. But it is questionable whether logic, regarded as something eluding the attempts of experimental psychology to explain it, can in its turn legitimately explain anything in psychological experience.

Non-locality. One of the most troubling aspects of field collapse is that it is instantaneous and occurs at the same time at widely separated points. Physicists call this non-locality. This is especially bothersome when the sudden change involves two entangled field quanta. Einstein argued vehemently against the idea of non-locality, claiming that it violated a result of his Principle of Relativity - that nothing can be transmitted faster than the speed of light. Now Einstein's postulate (which we must remember was only a guess) is indeed valid in relation to the evolution and propagation of fields as described by the field equations. However field collapse is not described by the field equations, so there is no reason to expect or to insist that it falls in the domain of Einstein's postulate. Non-locality is a fact; it has been experimentally documented. Nor does it lead to any paradoxes or inconsistencies. Even those who believe in particles as the ultimate reality acknowledge that something happens non-locally. Just as we said, "So the earth is round, not flat; that's surprising but I can live with it", so we can say, "Fields suddenly collapse. It's not what I expected but I can live with it." There are no logical contradictions involved.

Aluminum Hulls In 1931 England, aluminum was used in the construction of the Diana II, a 55 foot express cruiser, which is still in use. Aluminum is non-magnetic and is almost never found in the elemental state. As a ductile metal it is malleable and has about one-third the density and stiffness of steel. Aluminum is a corrosion resistant, easily machined, cast, drawn and extruded, however the procedure to weld it is more difficult and different from other metals. In 1935 the Bath Iron Works in Maine, built an experimental hull for Alcoa. Named the Alumette, it was floated to the James River in Newport News, Virginia for the purpose of testing its structural properties. The MV Sacal Borincano was an all-aluminum constructed Roll on Roll off, or Ro-Ro ship, designed to carry 40 highway trailers between Miami, FL and San Juan. PR. The relatively small ship was 226 feet in length and has a displacement of 2000 tons. The South Atlantic and Caribbean Line Inc. operated the vessel which was constructed by American Marine in 1967, with help from the Reynolds Metal Company. The vessel was constructed completely of heli-arced aluminum plates to achieve a working speed of 14 knots with a diesel electric power plant of 3000 hp generating 2240kW.

Notice that the p value works by assuming there is no difference between your experimental groups. This is a counterintuitive feature of significance testing: if you want to prove that your drug works, you do so by showing the data is inconsistent with the drug not working. Because of this, p values can be extended to any situation where you can mathematically express a hypothesis you want to knock down. But p values have their limitations. Remember, p is a measure of surprise, with a smaller value suggesting that you should be more surprised. It’s not a measure of the size of the effect. You can get a tiny p value by measuring a huge effect — “This medicine makes people live four times longer” — or by measuring a tiny effect with great certainty. And because any medication or intervention usually has some real effect, you can always get a statistically significant result by collecting so much data that you detect extremely tiny but relatively unimportant differences. As Bruce Thompson wrote, Statistical significance testing can involve a tautological logic in which tired researchers, having collected data on hundreds of subjects, then conduct a statistical test to evaluate whether there were a lot of subjects, which the researchers already know, because they collected the data and know they are tired. This tautology has created considerable damage as regards the cumulation of knowledge.1

April 8 His Resurrection Destiny Ought not Christ to have suffered these things, and to enter into His glory? Luke 24:26 Our Lord’s Cross is the gateway into His life: His Resurrection means that He has power now to convey His life to me. When I am born again from above (rv mg), I receive from the risen Lord His very life. Our Lord’s Resurrection destiny is to bring “many sons unto glory.” The fulfilling of His destiny gives Him the right to make us sons and daughters of God. We are never in the relationship to God that the Son of God is in; but we are brought by the Son into the relation of sonship. When Our Lord rose from the dead, He rose to an absolutely new life, to a life He did not live before He was incarnate. He rose to a life that had never been before; and His resurrection means for us that we are raised to His risen life, not to our old life. One day we shall have a body like unto His glorious body, but we can know now the efficacy of His resurrection and walk in newness of life. I would know Him in “the power of His resurrection.” “As Thou hast given Him power over all flesh, that He should give eternal life to as many as Thou hast given Him.” “Holy Spirit” is the experimental name for Eternal Life working in human beings here and now. The Holy Spirit is the Deity in proceeding power Who applies the Atonement to our experience. Thank God it is gloriously and majestically true that the Holy Ghost can work in us the very nature of Jesus if we will obey Him.

The value of using models rather than the real thing in experimentation is twofold. First, it can reduce the cost of an experiment-it can be much cheaper to crash a simulated BMW than a real one. Second, it can make experimental results clearer by making them simpler or otherwise different than real life. If one is trying to test the effect of a small change on car safety, for example, it can be helpful to remove everything not related to that change from the experiment. For example, if one is testing the way a particular wheel suspension structure deforms in a crash, one does not have to know (or spend time computing) how a taillight lens will react in the crash. Also, in a real crash things happen only once and happen very fast. In a virtual crash executed by computer, on the other hand, one can repeat the

a series of well-founded critiques were marshalled from within the new left, prompted partly by the experiences of women in activist groups, who found their voices continued to be marginalised even in allegedly radical organisations. More hierarchical organisational forms, such as parties or traditional union organisations, continued to entrench the predominant patriarchal and sexist social relations prevalent in broader society. Considerable experimentation was therefore conducted to produce new organisational forms that could work against this social repression. This included the use of consensus decision-making and horizontal debating structures that would later come to worldwide fame with the Occupy Wall Street movement.35

Unification of our theories of the Core interactions-strong, weak, and electromagnetic-into a single unified theory involves some guesswork, but the principles are clear. Quantum mechanics, special relativity, and (local) symmetry fit together smoothly. Using them, we can make definite suggestions for experimental exploration, including quantitative estimates of what to expect. Unification with gravity also looks good, at the level of comparing the fundamental strength of all the interactions, as we've seen. But with gravity our ideas about what the unified theory is are nowhere near as concrete. The ferment of ideas around super-string theory seems promising, but no one's been able to pull these ideas together enough to suggest specifically what new effects to expect.

MASS INCREASES The final paradox of relativity is the increase in mass due to motion. Mass increase has been observed experimentally in particle accelerators, with increases as great as 3000% for particles traveling at over 99.9% the speed of light. How can the mass of an object get bigger just because it's moving? Intuitive explanation. As we saw in Chapter 2, mass means inertia - i.e., resistance to acceleration. If you push something and it doesn't respond much, then by definition it has a large mass or inertia. Now we just saw that pushing on something that is traveling at close to the speed of light has little effect on its speed because the underlying fields are already moving almost as fast as they can. Thus its resistance to acceleration has become greater and this means its mass has increased. Mass increase is just another way of saying that fields can't propagate faster than c.

In this chapter we will look at the entire edifice of QFT. We will see that it is based on three simple principles. We will also list some of its achievements, including some new insights and understandings not previously mentioned. THE FOUNDATION QFT is an axiomatic theory that rests on a few basic assumptions. Everything you have learned so far, from the force of gravity to the spectrum of hydrogen, follows almost inevitably from these three basic principles. (To my knowledge, Julian Schwinger is the only person who has presented QFT in this axiomatic way, at least in the amazing courses he taught at Harvard University in the 1950's.) 1. The field principle. The first pillar is the assumption that nature is made of fields. These fields are embedded in what physicists call flat or Euclidean three-dimensional space-the kind of space that you intuitively believe in. Each field consists of a set of physical properties at every point of space, with equations that describe how these particles or field intensities influence each other and change with time. In QFT there are no particles, no round balls, no sharp edges. You should remember, however, that the idea of fields that permeate space is not intuitive. It eluded Newton, who could not accept action-at-a-distance. It wasn't until 1845 that Faraday, inspired by patterns of iron filings, first conceived of fields. The use of colors is my attempt to make the field picture more palatable. 2. The quantum principle (discetization). The quantum principle is the second pillar, following from Planck's 1900 proposal that EM fields are made up of discrete pieces. In QFT, all physical properties are treated as having discrete values. Even field strengths, whose values are continues, are regarded as the limit of increasingly finer discrete values. The principle of discretization was discovered experimentally in 1922 by Otto Stern and Walther Gerlach. Their experiment (Fig. 7-1) showed that the angular momentum (or spin) of the electron in a given direction can have only two values: +1/2 or -1/2 (Fig. 7-1). The principle of discretization leads to another important difference between quantum and classical fields: the principle of superposition. Because the angular momentum along a certain axis can only have discrete values (Fig. 7-1), this means that atoms whose angular momentum has been determined along a different axis are in a superposition of states defined by the axis of the magnet. This same superposition principle applies to quantum fields: the field intensity at a point can be a superposition of values. And just as interaction of the atom with a magnet "selects" one of the values with corresponding probabilities, so "measurement" of field intensity at a point will select one of the possible values with corresponding probability (see "Field Collapse" in Chapter 8). It is discretization and superposition that lead to Hilbert space as the mathematical language of QFT. 3. The relativity principle. There is one more fundamental assumption-that the field equations must be the same for all uniformly-moving observers. This is known as the Principle of Relativity, famously enunciated by Einstein in 1905 (see Appendix A). Relativistic invariance is built into QFT as the third pillar. QFT is the only theory that combines the relativity and quantum principles.

Over a year ago, Heather had read an article on quantum twins. Quantum theory predicted and experimentation had shown it possible to produce a pair of particles that shared the same quantum state. If something was done to one of the particles that changed its state, the state of the other particle changed at exactly the same time. This was true no matter how much distance separated the pair, something that at first glance appeared to violate the special theory of relativity’s prohibition on any information traveling faster than the speed of light. But the twin particles were bound together as if by magic.

In Depth Types of Effect Size Indicators Researchers use several different statistics to indicate effect size depending on the nature of their data. Roughly speaking, these effect size statistics fall into three broad categories. Some effect size indices, sometimes called dbased effect sizes, are based on the size of the difference between the means of two groups, such as the difference between the average scores of men and women on some measure or the differences in the average scores that participants obtained in two experimental conditions. The larger the difference between the means, relative to the total variability of the data, the stronger the effect and the larger the effect size statistic. The r-based effect size indices are based on the size of the correlation between two variables. The larger the correlation, the more strongly two variables are related and the more of the total variance in one variable is systematic variance related to the other variable. A third category of effect sizes index involves the odds-ratio, which tells us the ratio of the odds of an event occurring in one group to the odds of the event occurring in another group. If the event is equally likely in both groups, the odds ratio is 1.0. An odds ratio greater than 1.0 shows that the odds of the event is greater in one group than in another, and the larger the odds ratio, the stronger the effect. The odds ratio is used when the variable being measured has only two levels. For example, imagine doing research in which first-year students in college are either assigned to attend a special course on how to study or not assigned to attend the study skills course, and we wish to know whether the course reduces the likelihood that students will drop out of college. We could use the odds ratio to see how much of an effect the course had on the odds of students dropping out. You do not need to understand the statistical differences among these effect size indices, but you will find it useful in reading journal articles to know what some of the most commonly used effect sizes are called. These are all ways of expressing how strongly variables are related to one another—that is, the effect size. Symbol Name d Cohen’s d g Hedge’s g h 2 eta squared v 2 omega squared r or r 2 correlation effect size OR odds ratio The strength of the relationships between variables varies a great deal across studies. In some studies, as little as 1% of the total variance may be systematic variance, whereas in other contexts, the proportion of the total variance that is systematic variance may be quite large,

In many experiments, the boundary between seeing and not seeing is relatively sharp: an image is downright invisible when presented for 40 milliseconds, but is easily seen, on most trials, when the duration is increased to 60 milliseconds. This fonding justifies the use of the words subliminal (below threshhold) and supraliminal (above threshhold). Metaphorically, the gateway to consciousness is a well-defined threshhold, and a flashed image is either in or out. The length of the threshhold varies across subjects, but it always falls close to 50 milliseconds. At this duration, one perceives the flashed image about half the time. Presenting visual stimuli at threshhold therefore offers a wonderfully controlled experimental paradigm: the objective stimulus is constant, yet its subjective perception varies from trial to trial.

Nothing is more natural than the stagnation of experimental sciences in an era overly preoccupied with logic. There is something so absolute in the study of logical relations, since man cannot think outside them, that studying and handling them seems equivalent to possessing the entire world. The spirit that orders, places, and arranges logical concepts feels master of thought and the world.

The conventional explanation is that Raphael, Mendel, and Bach were always creative, only their reputation changed with the vagaries of social recognition. But the systems model recognizes the fact that creativity cannot be separated from its recognition. Mendel was not creative during his years of relative obscurity because his experimental findings were not that important until a group of British geneticists, at the end of the nineteenth century, recognized their implications for evolution.

In general the relation of the experimental sciences to life's question may be expressed thus: Question: "Why do I live?" Answer: "In infinite space, in infinite time, infinitely small particles change their forms in infinite complexity, and when you have understood the laws of those mutations of form you will understand why you live on the earth.

Queer contagion, including the anxiety triggered by gender nonnormativity, found its viral materiality in the early 1980s. The diagnosis of gay cancer, or GRID (gay-related immune disorder), the original name for AIDS, was a vengeful nomenclature for the perversion of existing in a world held together, at least in part, by trans/queer undoing. Found by chance, queers began showing symptoms of unexplainable illnesses such as Kaposi's sarcoma (KS) and Pneumocystis carinii pneumonia (PCP). Unresponsive to the most aggressive treatments, otherwise healthy, often well-resourced and white, young men were deteriorating and dying with genocidal speed. Without remedy, normative culture celebrated its triumph in knowing the tragic ends they always imagined queers would meet. This, while the deaths of Black, Brown, and Indigenous trans and cis women (queer or otherwise) were unthought beyond the communities directly around them. These women, along with many others, were stripped of any claim to tragedy under the conditions of trans/misogyny. Among the architects of this silence was then-President Ronald Reagan, who infamously refused to mention HIV/AIDS in public until 1986. By then, at least 16,000 had died in the U.S. alone. Collective fantasies of mass disappearance through the pulsing death of trans/queer people, Haitians, and drug users - the wish fulfillment of a nightmare world concertized the rhetoric that had always been spoken from the lips of power. The true terror of this response to HIV/AIDS was not only its methodological denial but its joyful humor. In Scott Calonico's experimental short film, "When AIDS Was Funny", a voice-over of Reagan's press secretary Larry Speakes is accompanied by iconic still images of people close to death in hospital beds. LESTER KINSOLVING: "Over a third of them have died. It's known as a 'gay plague.' [Press pool laughter.] No, it is. It's a pretty serious thing. One in every three people that get this have died. And I wonder if the president was aware of this." LARRY SPEAKES: "I don't have it. [Press pool laughter.] Do you?" LESTER KINSOLVING: "You don't have it? Well, I'm relieved to hear that, Larry!" [Press pool laughter.] LARRY SPEAKES: "Do you?" LESTER KINSOLVING: "No, I don't.

Kolb’s experiential learning cycle is a widely used explanation on how effective learning takes place (Kolb, 1983; Zull, 2002). Kolb’s cycle has four stages – namely, the concrete experience stage, reflective observation stage, abstract conceptualisation stage, and active experimentation stage. All four stages play important roles in accomplishing successful and effective learning. Kolb’s theory explains how different parts of the brain function together to affect effective learning; concrete experience is sensed through the sensory cortex; reflective observation is performed using the back integrative cortex; abstract conceptualisation is done using the frontal integrative cortex; and active experimentation is performed using motor cortex (Zull, 2002).

Using the characterisation of left and right hemispheric functions of the brain (Silverman, 2002), we can infer that concrete experience and active experimentation tasks mainly use the left hemisphere of our brain, while reflective observation and abstract conceptualisation activities use the right hemisphere; former functions may require detailed descriptions and a sense of time, while the latter probably needs to understand the big picture in the process of integrating and may not need to be concerned about the time or sequencing. In other words, we can infer that those who prefer auditory-sequential learning may prefer the concrete experience and active experimentation stages of the Kolb cycle, while visual-spatial learners may prefer the reflective observation and abstract conceptualisation stages.

Science is not only laboratory experimentation, spiritualism, society, field work, politics, arts, history, engineering and management, medicine everything is science. Star gazing is a science, sun gazing is a science, understanding animals and insects is science, understanding static and dynamic mechanisms of humans, living and non living things on universe and beyond is science. Understanding a women is science, understanding a men is science. Everything under umbrella of universal science. Who said christianity or islam is not related India and who said Vedas were written only by hindus? Who said himalayan monks are Indians? See Understanding myself is very simple if you are good I will be good, if you are bad I will be bad, If you play I will also play but personally I will not accept because you have so good, bad plays so I can not trust on you. And without trust I may consider you as a human being, if little care is there then friend or sister or brother not close friend or love because you already lost the trust when I gave a chance. I give chances to find purity and loyalty and I will not care afterwards and you will get hurt after sometime and you will miss after sometime, but I will not be there

The predictions of general relativity have been uniformly confirmed. There is no longer any doubt that Einstein's description of gravity is not only compatible with special relativity, but yields predictions closer to experimental results than those of Newton's theory.

use four-dimensional Riemannian geometry for his famed theory of relativity. Within seven decades, Theodr Kaluza at the University of Königsberg, Germany, would use five-dimensional Riemannian geometry to integrate both gravity and light. Light is now viewed as a vibration in the fifth dimension. Oskar Klein made several improvements, including the calculation of the size of the fifth dimension—the Planck length, which is 10-33 centimeters, much too small to detect experimentally. One hundred thirty years after Riemann’s famous lecture, physicists would extend the Kaluza-Klein constructs to develop ten-

Two men are travelling together along a road. One of them believes that it leads to a Celestial City, the other that it leads nowhere; but since this is the only road there is, both must travel it. Neither has been this way before, and therefore neither is able to say what they will find around each next comer. During their journey they meet both with moments of refreshment and delight, and with moments of hardship and danger. All the time one of them thinks of his journey as a pilgrimage to the Celestial City and interprets the pleasant parts as encouragements and the obstacles as trials of his purpose and lessons in endurance, prepared by the king of that city and designed to make of him a worthy citizen of the place when at last he arrives there. The other, however, believes none of this and sees their journey as an unavoidable and aimless ramble. Since he has no choice in the matter, he enjoys the good and endures the bad. But for him there is no Celestial City to be reached, no all-encompassing purpose ordaining their journey; only the road itself and the luck of the road in good weather and in bad. During the course of the journey the issue between them is not an experimental one. They do not entertain different expectations about the corning details of the road, but only about its ultimate destination. And yet when they do turn the last corner of it will be apparent that one of them has been right all the time and the other wrong. Thus although the issue between them has not been experimental, it has nevertheless from the start been a real issue. They have not merely felt differently about the road; for one was feeling appropriately and the other inappropriately in relation to the actual state of affairs. Their opposed interpretations of the road constituted genuinely rival assertions, though assertions whose assertion-status has the peculiar characteristic of being guaranteed retrospectively by a future crux.

The same pattern of movements may be performed by a swarm of fireflies, a flock of birds, a number of toy balloons or perhaps a flight of aeroplanes; the same machine, a bicycle or a cotton gin, a lathe, a telephone exchange or an adding machine, can be constructed from a large variety of materials and yet remains the same kind of machine within which elements of different individual properties will perform the same functionsyIn the same sense the peculiar properties of the elementary neural events which are the terms of the mental order have nothing to do with that order itself. What we have called physical properties of those events are those properties which will appear if they are placed in a variety of experimental relations to different other kinds of events. The mental properties are those which they possess only as a part of the particular structure and which may be largely independent of the former. It is at least conceivable that the particular kind of order which we call mind might be built up from anyone of several kinds of different elements — electrical, chemical, or what not; all that is required is that by the simple relationship of being able to evoke each other in a certain order they correspond to the structure which we call mind.

Like Lagrange, Michelson himself had already contributed unwittingly to the new system – in this case with an experimental result. In 1887 he and his colleague Edward Morley had observed that the speed of light relative to an observer remains constant when the observer moves.

The "pragmatic" position taken by many scientists and humanists who cannot be troubled to think about ultimate things--the position that these principles are no more than experimental hypotheses which collective experience finds reliable--is surely unsatisfactory; it may offer a psychological explanation of the faith these principles inspire, but since it does not establish the foundation of that faith in truth, it leaves the whole scientific edifice on shifting sands and provides no sure defense against the irrational winds that periodically attack it. [...] Every man, as we have seen, lives by faith; likewise every man--something less obvious but no less certain--is a metaphysician. The claim to any knowledge whatever--and no living man can refrain from this claim--implies a theory and standard of knowledge, and a notion of what is ultimately knowable and true. This ultimate truth, [...] is a metaphysical first principle, an absolute truth. But with the acknowledgement, logically unavoidable, of such a principle, the theory of the "relativity of truth" collapses, it itself being revealed as a selfcontradictory absolute.

The sources of covert racial bias are found all around us and are parts of US history. They are not particular to the criminal justice system, but given the powerful effects of race on criminal justice matters, and the over-representation of minorities in the criminal justice system, there should be no surprise that many associate crime with minorities, particularly young males. Crucially, according to the accumulated social psychological literature, no one growing up in mainstream US culture would be immune to these pressures (see for example Gillian and Iyengar 2000). Furthermore, within the police profession, there is ample reason to expect that such biases may be especially strong. In particular, as relates to the decision to shoot or not to shoot a hypothetical suspect in an ambiguous experimental setting, the black suspects are typically shot in a higher percentage of the cases than an identically situated white suspect (see for example Correll et al. 2002; Correll et al. 2007; Correll 2009).

Plasticity of neuroendocrine-thymus interactions during aging N.Fabris12E.Mocchegiani2M.Provinciali2 Abstract Thymic regrowth and reactivation of thymic endocrine activity may be achieved even in old animals by different endocrinological or nutritional manipulations such as, (a) intrathymic transplantation of pineal gland or treatment with melatonin, (b) implantation of a growth hormone (GH) secreting tumor cell line or treatment with exogenous GH, (c) castration or treatment with exogenous luteinizing hormone-releasing hormone (LH-RH), (d) treatment with exogenous thyroxine or triiodothyronine, and (e) nutritional interventions such as arginine or zinc supplementation. These data strongly suggest that thymic involution is a phenomenon secondary to age-related alterations in neuroendocrine-thymus interactions and that it is the disruption of such interactions in old age that is responsible for age-associated dysfunction. Melatonin or other pineal factors may act through specific receptors, but experimental evidence is still lacking. The role of zinc, whose turnover is usually reduced in old age, is diverse. The effects range from the reactivation of zinc-dependent enzymes, required for both cell proliferation and apoptosis, to the reactivation of thymulin, a zinc-dependent thymic hormone. The role of zinc may even be more crucial. According to recent preliminary data obtained both in animal and human studies, it appears that the above reported endocrinological manipulations capable of restoring thymic activity in old age, may act also by normalizing the altered zinc pool.

In game theory, as in applications of other technologies that use RPT [Revealed Preference Theory], the purpose of the machinery is to tell us what happens when patterns of behavior instantiate some particular strategic vector, payoff matrix, and distribution of information—for example, a PD [Prisoner's Dilemma]—that we’re empirically motivated to regard as a correct model of a target situation. The motivational history that produced this vector in a given case is irrelevant to which game is instantiated, or to the location of its equilibrium or equilibria. As Binmore (1994, pp. 95–256) emphasizes at length, if, in the case of any putative PD, there is any available story that would rationalize cooperation by either player, then it follows as a matter of logic that the modeler has assigned at least one of them the wrong utility function (or has mistakenly assumed perfect information, or has failed to detect a commitment action) and so made a mistake in taking their game as an instance of the (one-shot) PD. Perhaps she has not observed enough of their behavior to have inferred an accurate model of the agents they instantiate. The game theorist’s solution algorithms, in themselves, are not empirical hypotheses about anything. Applications of them will be only as good, for purposes of either normative strategic advice or empirical explanation, as the empirical model of the players constructed from the intentional stance is accurate. It is a much-cited fact from the experimental economics literature that when people are brought into laboratories and set into situations contrived to induce PDs, substantial numbers cooperate. What follows from this, by proper use of RPT, not in discredit of it, is that the experimental setup has failed to induce a PD after all. The players’ behavior indicates that their preferences have been misrepresented in the specification of their game as a PD. A game is a mathematical representation of a situation, and the operation of solving a game is an exercise in deductive reasoning. Like any deductive argument, it adds no new empirical information not already contained in the premises. However, it can be of explanatory value in revealing structural relations among facts that we otherwise might not have noticed.

Professional surveys that establish that the position that DID "does not exist" or that there is "no evidence" for the diagnosis are minority opinions, particularly among those who have any experience with alleged dissociative symptoms [12,13]. The related belief that traumatic memories cannot be forgotten is held by fewer than 10% of experimental psychologists and fewer than 5% of clinical psychologists [14].

He was, I realize now, one of the least ideological people I ever met: everything that happened to him he took as a particular case, unable or unwilling to generalize from it. He lost his livelihood but did not lose faith in his country. The education system failed him but he still revered it and placed all his hopes for his children in it. His relations with women were mostly disastrous but he did not hate women. In his mind he did not marry a black girl, he married "Yvonne," and he did not have an experimental set of mixed-race children, he had me and my brother Ben and my brother Luke. How rare such people are! I am not so naive even now as to believe we have enough of them at any one time in history to form a decent and tolerant society. But neither will I ever deny their existence or the possibility of lives like his. He was a member of the white working class, a man often afflicted by despair who still managed to retain a core optimism. Perhaps in a different time under different cultural influences living in a different society he would have become one of the rabid old angry white men of whom the present left is so afeared. As it was, born in 1925 and dying in 2006, he saw his children benefit from the civilized postwar protections of free education and free health care, and felt he had many reasons to be grateful.

Tufts will always be a second banana to Harvard in the Boston area, but given the Hub’s runaway popularity among college students, second is not so bad. Best-known for international relations, Tufts is also strong in engineering and health-related fields. In the Experimental College, students can take off-thewall courses for credit. (Rising Stars - Tufs University)

From where did all the initial matter and material processes through which we explain the recipe of life come from? All that we have done through science is to use the pre-existing matter inside the universe in ways that benefit us by exploiting the cause and effect relations from observation and experimentation.

The original Asch studies involved a group of seven to nine people sitting in a semi-circle taking it in turn to declare which of three simultaneously presented stimulus lines was the same length as a standard comparison line. Only the last person to respond was a true naïve subject, all the others, unbeknown to the subject, were confederates of the experimenter. … The results revealed that subjects registered incredulity and gave signs of distress and anxiety. Only 25 per cent managed to resist the group pressure throughout, 33 per cent conformed on half or more of the focal trials, and 5 per cent conformed on all of them. All in all subjects yielded on about 33 per cent of trials. Asch reasoned that since the stimuli were unambiguous subjects could not be using the others’ judgements as information about the correct response, rather they were conforming in order not to appear different or in order to avoid censure and rejection by the other members of the group

In answer to an inquiry Wilbur sent to the United States Weather Bureau in Washington about prevailing winds around the country, they were provided extensive records of monthly wind velocities at more than a hundred Weather Bureau stations, enough for them to take particular interest in a remote spot on the Outer Banks of North Carolina called Kitty Hawk, some seven hundred miles from Dayton. Until then, the farthest the brothers had been from home was a trip to Chicago for the Columbian Exposition of 1893. And though they had “roughed it” some on a few camping trips, it had been nothing like what could be expected on the North Carolina coast. To be certain Kitty Hawk was the right choice, Wilbur wrote to the head of the Weather Bureau station there, who answered reassuringly about steady winds and sand beaches. As could be plainly seen by looking at a map, Kitty Hawk also offered all the isolation one might wish for to carry on experimental work in privacy. Still further encouragement came when, on August 18, 1900, the former postmaster at Kitty Hawk, William J. Tate, sent a letter saying: Mr. J. J. Dosher of the Weather Bureau here has asked me to answer your letter to him, relative to the fitness of Kitty Hawk as a place to practice or experiment with a flying machine, etc. In answering I would say that you would find here nearly any type of ground you could wish; you could, for instance, get a stretch of sandy land one mile by five with a bare hill in center 80 feet high, not a tree or bush anywhere to break the evenness of the wind current. This in my opinion would be a fine place; our winds are always steady, generally from 10 to 20 miles velocity per hour. You can reach here from Elizabeth City, N.C. (35 miles from here) by boat . . . from Manteo 12 miles from here by mail boat every Mon., Wed., & Friday. We have telegraph communication & daily mails. Climate healthy, you could find good place to pitch tent & get board in private family provided there were not too many in your party; would advise you to come anytime from September 15 to October 15. Don’t wait until November. The autumn generally gets a little rough by November. If you decide to try your machine here and come, I will take pleasure in doing all I can for your convenience and success and pleasure, and I assure you you will find a hospitable people when you come among us. That decided the matter. Kitty Hawk it would be.

From ancient times and into the Middle Ages, man had dreamed of taking to the sky, of soaring into the blue like the birds. One savant in Spain in the year 875 is known to have covered himself with feathers in the attempt. Others devised wings of their own design and jumped from rooftops and towers—some to their deaths—in Constantinople, Nuremberg, Perugia. Learned monks conceived schemes on paper. And starting about 1490, Leonardo da Vinci made the most serious studies. He felt predestined to study flight, he said, and related a childhood memory of a kite flying down onto his cradle. According to brothers Wilbur and Orville Wright of Dayton, Ohio, it began for them with a toy from France, a small helicopter brought home by their father, Bishop Milton Wright, a great believer in the educational value of toys. The creation of a French experimenter of the nineteenth century, Alphonse Pénaud, it was little more than a stick with twin propellers and twisted rubber bands, and probably cost 50 cents. “Look here, boys,” said the Bishop, something concealed in his hands. When he let go it flew to the ceiling. They called it the “bat.” Orville’s first teacher in grade school, Ida Palmer, would remember him at his desk tinkering with bits of wood. Asked what he was up to, he told her he was making a machine of a kind that he and his brother were going to fly someday.

The study of stem cell niches in mammalian systems presents an 'arduous endeavor'; in comparison, the fly germarium is relatively easy to manipulate. In the 1990s, H. Lin, A.C. Spradling, and others used of a number of approaches to study Drosophilia GSCs and their niche, including killing specific cells in the germarium with precisely directed lasers; transplantation of cells from the ovary of one fly to another; and genetic perturbations that included the dialing up or down of Hh pathway signaling. The researchers found that following laser ablation of cells surrounding the GSCs - that is killing the niche cells - all the GSCs went on to form eggs, and the system was quickly depleted of its GSC reserve. Moreover, through genetic analyses the researchers identified specific genes required in the niche cells to maintain GSCs within the niche, as would be deduced for a gene that, when disrupted in niche cells, has the same effect as laser ablation of those cells. These studies are credited with providing the first clear experimental evidence of a stem cell niche, as well as defining what genes - what signaling pathways and other cellular activities - are important to the process. Many of the same pathways relevant in other cell types proved relevant to communication between the niche and GSCs, including the Hh pathway. The genes required for suppression of transposon mobilization by the piRNA system also have relevance to the GSC niche; disruption of the piwi gene, for example, can lead to uncontrolled proliferation of GSCs.

One of the things that a Mastermind promises to do is to allow every participant to make rapid progress, whether it relates to her/ his professional activity or to her/ his personal development. And we don’t believe that can be accomplished by avoiding the mention of the weak points that we perceive in others, or in their work, since we want to help everyone quickly. As partners in responsibility, the participants should, therefore, offer one another honest, sincere feedback that will help unleash some quantum leaps. A Mastermind group is a space where lightning fast experimentation and learning takes place. Participants’ feedback should also be lightning fast.