Esophageal Cancer Quotes

Before I was diagnosed with esophageal cancer a year and a half ago,” [Christopher] observed in his final column for Vanity Fair, “I rather jauntily told the readers of my memoirs that when faced with extinction I wanted to be fully conscious and awake, in order to ‘do’ death in the active and not the passive sense . . . However, one thing that grave illness does is to make you examine familiar principles and seemingly reliable sayings. And there’s one that I find I am not saying with quite the same conviction as I once used to: In particular, I have slightly stopped issuing the announcement that “Whatever doesn’t kill me makes me stronger.”6

Steve Harmon, thirty-six, had esophageal cancer growing at the inlet of his stomach. For six months, he had soldiered through chemotherapy as if caught in a mythical punishment cycle devised by the Greeks. He was debilitated by perhaps the severest forms of nausea that I had ever encountered in a patient, but he had to keep eating to avoid losing weight. As the tumor whittled him down week by week, he became fixated, absurdly, on the measurement of his weight down to a fraction of an ounce, as if gripped by the fear that he might vanish altogether by reaching zero. Meanwhile, a growing retinue of family members accompanied him to his clinic visits: three children who came with games and books and watched, unbearably, as their father shook with chills one morning; a brother who hovered suspiciously, then accusingly, as we shuffled and reshuffled medicines to keep Steve from throwing up; a wife who bravely shepherded the entire retinue through the whole affair as if it were a family trip gone horribly wrong. One morning, finding Steve alone on one of the reclining chairs of the infusion room, I asked him whether he would rather have the chemotherapy alone, in a private room. Was it, perhaps, too much for his family—for his children? He looked away with a flicker of irritation. “I know what the statistics are.” His voice was strained, as if tightening against a harness. “Left to myself, I would not even try. I’m doing this because of the kids.

Broadly speaking, components of processed foods and animal products, such as saturated fat, trans fat, and cholesterol, were found to be pro-inflammatory, while constituents of whole plant foods, such as fiber and phytonutrients, were strongly anti-inflammatory.938 No surprise, then, that the Standard American Diet rates as pro-inflammatory and has the elevated disease rates to show for it. Higher Dietary Inflammatory Index scores are linked to a higher risk of cardiovascular disease939 and lower kidney,940 lung,941 and liver function.942 Those eating diets rated as more inflammatory also experienced faster cellular aging.943,944 In the elderly, pro-inflammatory diets are associated with impaired memory945 and increased frailty.946 Inflammatory diets are also associated with worse mental health, including higher rates of depression, anxiety, and impaired well-being.947 Additionally, eating more pro-inflammatory foods has been tied to higher prostate cancer risk in men948,949,950 and higher risks of breast cancer,951,952 endometrial cancer,953 ovarian cancer,954 and miscarriages in women. Higher Dietary Inflammatory Index scores are also associated with more risk of esophageal,955 stomach,956 liver,957 pancreatic,958 colorectal,959 kidney,960 and bladder961 cancers, as well as non-Hodgkin lymphoma.962 Overall, eating a more inflammatory diet was associated with 75 percent increased odds of having cancer and 67 percent increased risk of dying from cancer.963 Not surprisingly, those eating more anti-inflammatory diets appear to live longer lives.964,965,966,967 But how does the Dietary Inflammatory Index impact body weight? Obesity and Inflammation:

number of chemotherapy drugs have been developed to restore our bodies’ natural defenses, but their use has been limited due to their high toxicity.107 There are, however, a number of compounds distributed widely throughout the plant kingdom—including beans, greens, and berries—that appear to have the same effect naturally.108 For example, dripping green tea on colon, esophageal, or prostate cancer cells has been shown to reactivate genes silenced by the cancer.109

Instantly, I was overwhelmed with gratitude. I didn't know exactly what I was feeling, but my buddy JD - my best man, whom I had met at Northwestern - has seen his dad go through (and beat) esophageal cancer and explained it to me thusly: "When you have cancer, it's like you're at the bottom of a hole, and you just want to get out. Only it's too big for you to just climb out easily. But every good thing that happens - no matter how small - is like a rock in the side of the hole. You climb up, grabbing one little rock at a time. Had a good doctor's appointment? That's a rock. Feeling a little better today? That's a rock, too. Before you know it, you've climbed out of that hole, one little rock at a time. You just need to find the rocks.

One mechanism is that zolpidem (and probably other sleeping pills) relax the stomach sphincter and cause gastro-esophageal regurgitation. The acid irritation may lead to infection. Incidentally, acid regurgitation may also lead to esophageal cancer, which is one of the cancers most greatly increased among sleeping pill users. At

disease76 375,000 2. Lung diseases (lung cancer,77 COPD, and asthma78) 296,000 3. You’ll be surprised! (see chapter 15) 225,000 4. Brain diseases (stroke79 and Alzheimer’s80) 214,000 5. Digestive cancers (colorectal, pancreatic, and esophageal)81 106,000 6. Infections (respiratory and blood)82 95,000 7. Diabetes83 76,000 8. High blood pressure84 65,000 9. Liver disease (cirrhosis and cancer)85 60,000 10. Blood cancers (leukemia, lymphoma, and myeloma)86 56,000 11. Kidney disease87 47,000 12. Breast cancer88 41,000 13. Suicide89 41,000 14. Prostate cancer90 28,000 15. Parkinson’s disease91 25,000

Can Strawberries Reverse the Development of Esophageal Cancer? Esophageal cancer joins pancreatic cancer as one of the gravest diagnoses imaginable. The five-year survival rate is less than 20 percent,124 with most people dying within the first year after diagnosis.125 This underscores the need to prevent, stop, or reverse the disease process as early as possible. Researchers decided to put berries to the test. In a randomized clinical trial of powdered strawberries in patients with precancerous lesions in their esophagus, subjects ate one to two ounces of freeze-dried strawberries every day for six months—that’s the daily equivalent of about a pound of fresh strawberries.126 All of the study participants started out with either mild or moderate precancerous disease, but, amazingly, the progression of the disease was reversed in about 80 percent of the patients in the high-dose strawberry group. Most of these precancerous lesions either regressed from moderate to mild or disappeared entirely. Half of those on the high-dose strawberry treatment walked away disease-free.127

sometimes find a way to turn them off. A number of chemotherapy drugs have been developed to restore our bodies’ natural defenses, but their use has been limited due to their high toxicity.107 There are, however, a number of compounds distributed widely throughout the plant kingdom—including beans, greens, and berries—that appear to have the same effect naturally.108 For example, dripping green tea on colon, esophageal, or prostate cancer cells has been shown to reactivate genes silenced by the cancer.109 This hasn’t just been demonstrated in a petri dish, though. Three hours after eating a cup of broccoli sprouts, the enzyme that cancers use to help silence our defenses is suppressed in your bloodstream110 to an extent equal to or greater than the chemotherapy agent specifically designed for that purpose,111 without the toxic side effects.112

In 2003, epidemiologists from the Centers for Disease Control, led by Eugenia Calle, published an analysis in The New England Journal of Medicine reporting that cancer mortality in the United States was clearly associated with obesity and overweight. The heaviest men and women, they reported, were 50 and 60 percent more likely, respectively, to die from cancer than the lean. This increased risk of death held true for a host of common cancers—esophageal, colorectal, liver, gallbladder, pancreatic, and kidney cancers, as well as, in women, cancers of the breast, uterus, cervix, and ovary. In 2004, the CDC followed up with an analysis linking cancer to diabetes, particularly pancreatic, colorectal, liver, bladder, and breast cancers. Cancer researchers trying to make sense of this association would later say that something about cancer seems to thrive on the metabolic environment of the obese and the diabetic. One conspicuous clue as to what that something might be was that the same association was seen with people who weren’t obese and diabetic (or at least not yet) but suffered only from metabolic syndrome and thus were insulin-resistant. The higher their levels of circulating insulin, and that of a related hormone known as insulin-like growth factor, the greater the likelihood that they would get cancer.

Here are the odds of five-year survival for several common cancers: Cancer Type Odds If Localized If Spread to Lymph Nodes Odds If Metastatic Chance of Getting It Chance of Dying From It Malignant Melanoma 90% 10% 2.5% 0.5% Squamous Cell Skin Cancer ~100% 10% 7.5% 0.01% Bladder Cancer 88% 55% 15% 2.5% 0.6% Breast Cancer ~100% 72% 22% 12% 3% Prostate Cancer ~100% ~100% 28% 15% 2.6% Colorectal Cancer 92% 65% 11% 4.6% 1.9% Esophageal Cancer 40% 21% 4% 0.9% 0.7% Lung Cancer 31% 15% 2% 6.8% 5.8% Pancreatic Cancer 14% 7% 1% 1.5% 1.35% Liver Cancer 28% 7% 2% Leukemia Varies Varies Varies 1.4% 0.8%