Epidemiology Quotes

It seems like it’s been fairly well contained,” but here’s an epidemiological question: if you’re talking about outbreaks of infectious disease, isn’t fairly well contained essentially the same thing as not contained at all?

Given the link between belief and action, it is clear that we can no more tolerate a diversity of religious beliefs than a diversity of beliefs about epidemiology and basic hygiene.

But we've all ended up giving body and soul to Africa, one way or another. Even Adah, who's becoming an expert in tropical epidemiology and strange new viruses. Each of us got our heart buried in six feet of African dirt; we are all co-conspirators here. I mean, all of us, not just my family. So what do you do now? You get to find your own way to dig out a heart and shake it off and hold it up to the light again.

Whether epidemiology alone can, in strict logic, ever prove causality, even in this modern sense, may be questioned, but the same must also be said of laboratory experiments on animals. —Richard Doll

To take care of cancer patients is an enormous privilege, but it also involves deploying everything in your toolbox: the emotional, the psychological, the scientific, the epidemiologic.

Rumors had their own classic epidemiology. Each started with a single germinating event. Information spread from that point, mutating and interbreeding—a conical mass of threads, expanding into the future from the apex of their common birthplace. Eventually, of course, they'd wither and die; the cone would simply dissipate at its wide end, its permutations senescent and exhausted. There were exceptions, of course. Every now and then a single thread persisted, grew thick and gnarled and unkillable: conspiracy theories and urban legends, the hooks embedded in popular songs, the comforting Easter-bunny lies of religious doctrine. These were the memes: viral concepts, infections of conscious thought. Some flared and died like mayflies. Others lasted a thousand years or more, tricked billions into the endless propagation of parasitic half-truths.

From this cascade comes a prediction: getting too little sleep across the adult life span will significantly raise your risk of developing Alzheimer’s disease. Precisely this relationship has now been reported in numerous epidemiological studies, including those individuals suffering from sleep disorders such as insomnia and sleep apnea.VIII Parenthetically, and unscientifically, I have always found it curious that Margaret Thatcher and Ronald Reagan—two heads of state that were very vocal, if not proud, about sleeping only four to five hours a night—both went on to develop the ruthless disease. The current US president, Donald Trump—also a vociferous proclaimer of sleeping just a few hours each night—may want to take note.

Most people do not know what epidemiology is or how it contributes to the health of our society. This fact is somewhat paradoxical, given that epidemiology pervades oir lives.

Poison is a glyph for magical power itself: complex, concentrated, liberated in the hands of the elect, and disastrous in the hands of the fool. Its very nature is transmutative, changing all it touches, the maker and breaker of laws, policies, and epidemiological systems.

Your frequent claim that we must understand religious belief as a “social construct,” produced by “societal causes,” dependent upon “social and cultural institutions,” admitting of “sociological questions,” and the like, while it will warm the hearts of most anthropologists, is either trivially true or obscurantist. It is part and parcel of the double standard that so worries me—the demolition of which is the explicit aim of The Reason Project. Epidemiology is also a “social construct” with “societal causes,” etc.—but this doesn’t mean that the germ theory of disease isn’t true or that any rival “construct”—like one suggesting that child rape will cure AIDS—isn’t a dangerous, deplorable, and unnecessary eruption of primeval stupidity. We either have good reasons or bad reasons for what we believe; we can be open to evidence and argument, or we can be closed; we can tolerate (and even seek) criticism of our most cherished views, or we can hide behind authority, sanctity, and dogma. The main reason why children are still raised to think that the universe is 6,000 years old is not because religion as a “social institution” hasn’t been appropriately coddled and cajoled, but because polite people (and scientists terrified of losing their funding) haven’t laughed this belief off the face of the earth. We did not lose a decade of progress on stem-cell research in the United States because of religion as a “social construct”; we lost it because of the behavioural and emotional consequences of a specific belief. If there were a line in the book of Genesis that read – “The soul enters the womb on the hundredth day (you idiots)” – we wouldn’t have lost a step on stem-cell research, and there would not be a Christian or Jew anywhere who would worry about souls in Petri dishes suffering the torments of the damned. The beliefs currently rattling around in the heads of human beings are some of the most potent forces on earth; some of the craziest and most divisive of these are “religious,” and so-dubbed they are treated with absurd deference, even in the halls of science; this is a very bad combination—that is my point.

In the post-Covid world, the mathematics of chaos theory will experience a greater relevancy as it is applied across a broader set of science disciplines, especially epidemiology, precision medicine and climate science. - Tom Golway

The accelerating pace of zoonotic transmission of novel viruses into humans is attributable to anthropogenic epidemiologic factors. Only behavior modification or medical management of this future health burden will minimize the risks of future zoonoses for human populations.

Changing mainstream media will be hard, but you can help create parallel options. More academics should blog, post videos, post audio, post lectures, offer articles, and more. You’ll enjoy it: I’ve had threats and blackmail, abuse, smears and formal complaints with forged documentation. But it’s worth it, for one simple reason: pulling bad science apart is the best teaching gimmick I know for explaining how good science works.

One thing is clear,” they continued about the two recently published epidemiological studies, “statistical association must not be immediately equated with cause and effect.

The important thing is that, thanks to epidemiological studies, we know that exercise is the most powerful anti-aging tactic we’ve got.

In this, the largest epidemiological study ever conducted, the highest life expectancy is among individuals who are overweight by our current standards and the lowest life expectancy is among those defined as underweight. What’s more, individuals who fit into what is deemed the ideal weight range had a lower life expectancy than some of those who were obese.)

Epidemiology is in fact a mathematical subject,’ he wrote in 1911, ‘and fewer absurd mistakes would be made regarding it (for example, those regarding malaria) if more attention were given to the mathematical study of it.’[28]

The principle of critical mass is so simple that it is no wonder that it shows up in epidemiology, fashion, survival and extinction of species, language systems, racial integration, jaywalking, panic behavior, and political movements.

That’s because I believe in what I call consequential epidemiology. That is, by attempting to change what could happen if we don’t act, we can positively alter the course of history, rather than merely record and explain it retrospectively.

These epidemiological and experimental studies have provided evidence for a dietary pattern that is associated with reduced risk of developing cancer, atherosclerosis and cardiovascular disease, hypertension and stroke, and type II diabetes.

NBC News "Lead from gasoline blunted the IQ of about half the U.S. population, study says" by Elizabeth Chuck …on a population basis, shifting the average IQ down even a small amount could have large consequences, said Sung Kyun Park, an associate professor of epidemiology and environmental health sciences at the University of Michigan School of Public Health. The entire bell curve shifts, he explained, with more of the population at what was once the extreme low end of IQ scores.

Center for Disease Control in Atlanta is a striking case in point. Its network of sample hospitals allowed it to first “discover”—in the epidemiological sense—such hitherto unknown diseases as toxic shock syndrome, Legionnaire’s disease, and AIDS.

In his airport bestseller from 2018, Enlightenment Now, Steven Pinker, the leading voice in the choir of bourgeois optimism, revelled in the ‘conquest of infectious disease’ all over the globe – Europe, America, but above all the developing countries – as proof that ‘a rich world is a healthier world’, or, in transparent terms, that a world under the thumb of capital is the best of all possible worlds. ‘ “Smallpox was an infectious disease” ’, Pinker read on Wikipedia – ‘yes, “smallpox was” ’; it exists no more, and the diseases not yet obliterated are being rapidly decimated. Pinker closed the book on the subject by confidently predicting that no pandemic would strike the world in the foreseeable future. Had he cared to read the science, he would have known that waves from a rising tide were already crashing against the fortress he so dearly wished to defend. He could, for instance, have opened the pages of Nature, where a team of scientists in 2008 analysed 335 outbreaks of ‘emerging infectious diseases’ since 1940 and found that their number had ‘risen significantly over time’.

...because she remembered saying It seems like it's been fairly well contained, but here's an epidemiological question: if you're talking about outbreaks of infectious disease, isn't fairly well contained essentially the same thing as not contained at all? ... A virus is either contained or it isn't. It's a binary condition.

A number of prominent epidemiological studies have reported that nighttime shift work, and the disruption to circadian rhythms and sleep that it causes, up your odds of developing numerous different forms of cancer considerably. To date, these include associations with cancer of the breast, cancer of the prostate, cancer of the uterus wall or the endometrium, and cancer of the colon.

To comprehend the interactions between Homo sapiens and the vast and diverse microbial world, perspectives must be forged that meld such disparate fields as medicine, environmentalism, public health, basic ecology, primate biology, human behavior, economic development, cultural anthropology, human rights law, entomology, parasitology, virology, bacteriology, evolutionary biology, and epidemiology.

Gilligan makes it very clear what the most powerful generator of shame and humiliation is in human culture, according to his extensive study. As corroborated by others in epidemiological research, socioeconomic inequality appears to be the greatest driver of behavioral violence in general. Gilligan states, “Worldwide, the most powerful predictor of the murder rate is the size of the gap in income and wealth between the rich and the poor. The most powerful predictor of the rate of national or collective violence—war, civil insurrection, and terrorism—is the size of the gap between income and wealth between the rich and poor nations.”46 This is a troubling finding as wealth inequity is a textbook characteristic of capitalism, effectively making capitalism itself a precondition for war and violence.

How do you know?" Red repeated each word slowly, enunciating every consonant. "If the CDC brewed up something in their lab and it accidentally was let loose in the world, do you think they would tell you?

Many women, worried about breast cancer, have adopted vegetarian diets in an attempt to reduce their risk. Unfortunately, it may be that these grain- and starch-based diets actually increase the risk of breast cancer, because they elevate insulin—which, in turn, increases IGF-1 and lowers IGFBP-3. A large epidemiological study of Italian women, led by Dr. Silvia Franceschi, has shown that eating large amounts of pasta and refined bread raises the risk of developing both breast and colorectal cancer. Most vegetarian diets are based on starchy grains and legumes. Sadly—despite continuing perceptions of these as healthy foods—vegetarian diets don’t reduce the risk of cancer. In the largest-ever study comparing the causes of death in more than 76,000 people, it was decisively shown that there were no differences in death rates from breast, prostate, colorectal, stomach, or lung cancer between vegetarians and meat eaters. Cancer is a complex process involving many genetic and environmental factors. It is almost certain that no single dietary element is responsible for all cancers. However, with the low-glycemic Paleo Diet, which is also high in lean protein and health-promoting fruits and vegetables, your risk of developing many types of cancer may be very much reduced.

[...] I’m very grateful to all the many companies and people who, by their optimistically bad behaviour under fire, have given narrative colour to what might otherwise have been some very dry explanations of basic statistical principles.

By the end of 1986, the Liquidators had decontaminated more than 600 villages and towns. Army troops travelling in armoured vehicles washed Kiev’s buildings continually throughout May and June, and it became a crime to own a personal dosimeter in the city for more than two years after the accident. The government placed strict controls on the sale of fresh food; open-air stalls were banned. These restrictions lead the Head of the Central Sanitary and Epidemiological Service of the Ukraine to remark that, “thousands of ice cream, cake and soft drink stalls have vanished from the streets of Kiev.228

increases of the infectivity rate may lead to large epidemics.” This quiet warning has echoed loudly ever since. It’s a cardinal truth, over which public health officials obsess each year during influenza season. Another implication was that epidemics don’t end because all the susceptible individuals are either dead or recovered. They end because susceptible individuals are no longer sufficiently dense within the population. W. H. Hamer had said so in 1906, remember? Ross had made the same point in 1916. But the paper by Kermack and McKendrick turned it into a working principle of mathematical epidemiology.

Epidemiologists-scientists who study the spread of disease-use a special number to describe how contagious a virus is. It's called the basic reproduction number, or R0 for short. It's complicated to calculate but simple to understand-it counts how many people one sick person is expected to infect over the course of his or her illness. If I'm sick with a cold and I make two other people sick, the R0 of my virus is 2. Colds and seasonal flus typically have R0 values of around 1.5 to 2. The 1918 flu pandemic R0 was estimated to be 2 to 3, while diseases like polio and small pox have R0 values of around 5 to 7.

Krieger took the first scientific step by partnering with physician Stephen Sidney to specifically measure research participants’ exposure to racial discrimination and test its association with high blood pressure. Instead of treating race as a biological risk factor, as was typical in epidemiological research, Krieger zoomed in on racism as a cause of disease and developed a fledgling methodology to measure its health impact directly. Her findings, published in the American Journal of Public Health in 1996, were the first to show that experiencing racial discrimination raises the risk of high blood pressure.

For some reason there is a tendency to assume that one wild animal is a suitable model for another related species, whereas similar evidence would not be acceptable in human or veterinary medicine. For example, Shulaw etal. (1986) developed a serologic test to detect antibodies to Mycobacterium aviumssp. paratuberculosisin white-tailed deer, but determined the validity of the test “in deer” by using samples from infected sika and fallow deer. It is doubtful that a test developed to detect disease in humans would be accepted for use in public health circles, if its validity had been established by using squirrel monkeys and baboons!

The power of a study typically should be set at 80% or greater, so if there is truly a difference in treatments, the chances are 80% or greater that your research project will identify this fact. Power = 1 - beta. Beta is the probability of making a Type II error (accepting the null hypothesis when in fact it is incorrect).

Let’s start with “leaner.” Legions of Atkins and Paleo dieters—as well as obesity experts—fiercely contest the superiority of a plant-based diet for making you “leaner.” Like all nutrition science, the science of weight loss is complicated and uncertain. The relative effectiveness of moderate exercise, long thought a key component in reducing obesity rates, is now under scrutiny. (A recent editorial in the International Journal of Epidemiology is titled “Physical activity does not influence obesity risk: time to clarify the public health message.”) Even the wisdom of gradual weight loss is questionable, in light of a new study that suggests crash dieters don’t gain back weight any more than dieters who drop pounds gradually.

One of the central elements of resilience, Bonanno has found, is perception: Do you conceptualize an event as traumatic, or as an opportunity to learn and grow? “Events are not traumatic until we experience them as traumatic,” Bonanno told me, in December. “To call something a ‘traumatic event’ belies that fact.” He has coined a different term: PTE, or potentially traumatic event, which he argues is more accurate. The theory is straightforward. Every frightening event, no matter how negative it might seem from the sidelines, has the potential to be traumatic or not to the person experiencing it. Take something as terrible as the surprising death of a close friend: you might be sad, but if you can find a way to construe that event as filled with meaning—perhaps it leads to greater awareness of a certain disease, say, or to closer ties with the community—then it may not be seen as a trauma. The experience isn’t inherent in the event; it resides in the event’s psychological construal. It’s for this reason, Bonanno told me, that “stressful” or “traumatic” events in and of themselves don’t have much predictive power when it comes to life outcomes. “The prospective epidemiological data shows that exposure to potentially traumatic events does not predict later functioning,” he said. “It’s only predictive if there’s a negative response.” In other words, living through adversity, be it endemic to your environment or an acute negative event, doesn’t guarantee that you’ll suffer going forward. What matters is whether that adversity becomes traumatizing.

The Company We Keep So now we have seen that our cells are in relationship with our thoughts, feelings, and each other. How do they factor into our relationships with others? Listening and communicating clearly play an important part in healthy relationships. Can relationships play an essential role in our own health? More than fifty years ago there was a seminal finding when the social and health habits of more than 4,500 men and women were followed for a period of ten years. This epidemiological study led researchers to a groundbreaking discovery: people who had few or no social contacts died earlier than those who lived richer social lives. Social connections, we learned, had a profound influence on physical health.9 Further evidence for this fascinating finding came from the town of Roseto, Pennsylvania. Epidemiologists were interested in Roseto because of its extremely low rate of coronary artery disease and death caused by heart disease compared to the rest of the United States. What were the town’s residents doing differently that protected them from the number one killer in the United States? On close examination, it seemed to defy common sense: health nuts, these townspeople were not. They didn’t get much exercise, many were overweight, they smoked, and they relished high-fat diets. They had all the risk factors for heart disease. Their health secret, effective despite questionable lifestyle choices, turned out to be strong communal, cultural, and familial ties. A few years later, as the younger generation started leaving town, they faced a rude awakening. Even when they had improved their health behaviors—stopped smoking, started exercising, changed their diets—their rate of heart disease rose dramatically. Why? Because they had lost the extraordinarily close connection they enjoyed with neighbors and family.10 From studies such as these, we learn that social isolation is almost as great a precursor of heart disease as elevated cholesterol or smoking. People connection is as important as cellular connections. Since the initial large population studies, scientists in the field of psychoneuroimmunology have demonstrated that having a support system helps in recovery from illness, prevention of viral infections, and maintaining healthier hearts.11 For example, in the 1990s researchers began laboratory studies with healthy volunteers to uncover biological links to social and psychological behavior. Infected experimentally with cold viruses, volunteers were kept in isolation and monitored for symptoms and evidence of infection. All showed immunological evidence of a viral infection, yet only some developed symptoms of a cold. Guess which ones got sick: those who reported the most stress and the fewest social interactions in their “real life” outside the lab setting.12 We Share the Single Cell’s Fate Community is part of our healing network, all the way down to the level of our cells. A single cell left alone in a petri dish will not survive. In fact, cells actually program themselves to die if they are isolated! Neurons in the developing brain that fail to connect to other cells also program themselves to die—more evidence of the life-saving need for connection; no cell thrives alone. What we see in the microcosm is reflected in the larger organism: just as our cells need to stay connected to stay alive, we, too, need regular contact with family, friends, and community. Personal relationships nourish our cells,

Roughly 25 percent of humanity is Muslim. For every Jew, there are roughly one hundred twenty-five Muslims. Judaism is about 2500 years older than Islam, and yet it has not been able to attract nearly as many followers. If we construe religions as memeplexes (a collection of interconnected memes), to borrow Richard Dawkin's term, the Islamic memeplex has been extraordinarily more successful than its Jewish counterpart (from an epidemiological perspective, that is). Why is that? To answer this important question, we must look at the contents of the two respective memeplexes to examine why one is more "infectious" than the other. Let us explore the rules for converting into the two religions and apostatizing out of them. In Judaism, the religious process for conversion is onerous, requiring several years of commitment and an absence of ulterior motive. (For example, converting to Judaism because you are marrying a Jewish person is considered an ulterior motive). Not surprisingly, given the barriers to entry, relatively few people convert to Judaism. On the other hand, to convert to Islam simply requires that one proclaim openly the sentence, the shahada (the testimony): "There is no true god but Allah, and Muhammad is the Messenger of Allah." It does not require a sophisticated epidemiological model to predict which memeplex will spread more rapidly. Let us now suppose that one wishes to leave the religion. While the Old Testament does mention the death penalty for apostasy, it has seldom been applied throughout Jewish history, whereas to this day apostasy from Islam does lead to the death penalty in several Islamic countries. But perhaps the most important difference is that Judaism does not promote or encourage proselytizing, whereas it is a central religious obligation in Islam. According to Islam, the world is divided into dar al-hard (the house of war) and dar al-Islam (the house of Islam). Peace will arrive when the entire world is united under the flag of Allah. Hence, it is imperative to Islamize the nations within dar al-harb. There is only one Jewish country in the world, Israel, and it has a sizeable non-Jewish minority. But there are fifty-seven member states of the Organization of Islamic Cooperation.

In April, Dr. Vladimir (Zev) Zelenko, M.D., an upstate New York physician and early HCQ adopter, reproduced Dr. Didier Raoult’s “startling successes” by dramatically reducing expected mortalities among 800 patients Zelenko treated with the HCQ cocktail.29 By late April of 2020, US doctors were widely prescribing HCQ to patients and family members, reporting outstanding results, and taking it themselves prophylactically. In May 2020, Dr. Harvey Risch, M.D., Ph.D. published the most comprehensive study, to date, on HCQ’s efficacy against COVID. Risch is Yale University’s super-eminent Professor of Epidemiology, an illustrious world authority on the analysis of aggregate clinical data. Dr. Risch concluded that evidence is unequivocal for early and safe use of the HCQ cocktail. Dr. Risch published his work—a meta-analysis reviewing five outpatient studies—in affiliation with the Johns Hopkins Bloomberg School of Public Health in the American Journal of Epidemiology, under the urgent title, “Early Outpatient Treatment of Symptomatic, High-Risk COVID-19 Patients that Should be Ramped-Up Immediately as Key to Pandemic Crisis.”30 He further demonstrated, with specificity, how HCQ’s critics—largely funded by Bill Gates and Dr. Tony Fauci31—had misinterpreted, misstated, and misreported negative results by employing faulty protocols, most of which showed HCQ efficacy administered without zinc and Zithromax which were known to be helpful. But their main trick for ensuring the protocols failed was to wait until late in the disease process before administering HCQ—when it is known to be ineffective. Dr. Risch noted that evidence against HCQ used late in the course of the disease is irrelevant. While acknowledging that Dr. Didier Raoult’s powerful French studies favoring HCQ efficacy were not randomized, Risch argued that the results were, nevertheless, so stunning as to far outweigh that deficit: “The first study of HCQ + AZ [ . . . ] showed a 50-fold benefit of HCQ + AZ vs. standard of care . . . This is such an enormous difference that it cannot be ignored despite lack of randomization.”32 Risch has pointed out that the supposed need for randomized placebo-controlled trials is a shibboleth. In 2014 the Cochrane Collaboration proved in a landmark meta-analysis of 10,000 studies, that observational studies of the kind produced by Didier Raoult are equal

A 2009 study in the American Journal of Epidemiology called “Life-Course Socioeconomic Position and Incidence of Coronary Heart Disease” found that the longer a person remains in poverty, the more likely he or she is to develop heart disease.133 People who were economically disadvantaged throughout life were more likely to smoke, be obese, and have poor diets and the like. In an earlier study by epidemiologist Dr. Ralph R. Frerichs, focusing specifically on the socioeconomic divide in the city of Los Angeles, CA, found that the death rate from heart disease was 40 percent higher for poor men over all than for wealthier ones.134

In spite of the weakness of the epidemiological evidence linking nitrites to cancer, and the established fact that 95 per cent of all the nitrite we ingest comes from bacterial conversion of nitrates naturally found in vegetables, many consumers have a lingering concern about eating nitrite-cured processed meats. But one person’s concern is another’s business opportunity.

According to recent epidemiological data, the “lifetime incidence” of anxiety disorder is more than 25 percent—which, if true, means that one in four of us can expect to be stricken by debilitating anxiety at some point in our lifetimes. And it is debilitating: Recent academic papers have argued that the psychic and physical impairment tied to living with an anxiety disorder is equivalent to living with diabetes—usually manageable, sometimes fatal, and always a pain to deal with.

Epidemiologic theory. As a phrase, it sounds at once dry and arcane.Yet, in reality, it is vital and engaging. Epidemiologic theory is about explaining the people’s health. It is about life and death. It is about biology and society. It is about ecology and the economy. It is about how the myriad activities and meanings of people’s lives—involving work, dignity, desire, love, play, confl ict, discrimination, and injustice—become literally incorporated into our bodies—that is, embodied—and manifest in our health status, individually and collectively. It is about why rates of disease and death change over time and vary geographically. It is about why different societies—and within societies, why different societal groups—have better or worse health than others. And it is about essential knowledge critical for improving the people’s health and minimizing inequitable burdens of disease, disability, and death

A recent study in the American Journal of Epidemiology followed 123,216 subjects over fourteen years and found that men who spent more than 6 hours a day sitting were 17 percent more likely to die during that time than men who sat for less than 3 hours. For women, the increased risk of death was 34 percent. This increased mortality persisted regardless of whether the participants smoked, were overweight, and—this shocked me—regardless of how much they exercised. Humans aren’t built to sit all day.

Cardiovascular Morbidity and Obstructive Sleep Apnea Robert C. Basner, M.D. | 1405 words Volume 370:2339-2341 Number 24 June 12, 2014 Obstructive sleep apnea, a relatively common disorder in adults, is characterized by sleep-related periodic breathing, upper-airway obstruction and asphyxia, sleep disruption, and acute autonomic, arterial, and hemodynamic perturbations. Epidemiologic data show a strong association between untreated obstructive sleep apnea and incident cardiovascular morbidity and mortality. 1, 2 It is implicit that obstructive sleep apnea causes or propagates adverse cardiovascular outcomes and that its treatment may have a mitigating effect, and there are numerous instances in which explicit data have documented the efficacy of the treatment of obstructive sleep apnea in preventing or attenuating such outcomes. However, obstructive sleep apnea is typically identified along with cardiovascular, metabolic, and inflammatory disorders, and this “complicit” association confounds interpretation of the implicit and explicit associations between the treatment of obstructive sleep apnea and cardiovascular risk and outcomes.

Retrospective epidemiological studies report that 20% of the general population qualifies for a current psychiatric diagnosis and 50% for a lifetime one.4 Prospective epidemiological studies double these rates and suggest that mental disorder is becoming virtually ubiquitous.5, 6 During the past

western notions of medicine were based largely on superstition and exorcism in contrast to the Arab’s advanced clinical training and understanding of surgery, pharmacology and epidemiology. Westerners had no knowledge of ‘hygiene’ and sanitation’.

A common feature of epidemiological data is that they are almost certain to be biased, of doubtful quality, or incomplete (and sometimes all three),” explained the epidemiologist John Bailar

Krauss and his colleagues concluded that “saturated fat was not associated with an increased risk” for heart disease or stroke. This was the first time a researcher had analyzed all the epidemiological studies together, and Krauss found that they amounted to an absence of incriminating evidence.

work and a minority that is too ill to work. The latter

The inattention to disability within this topic area can be traced to a view dominated by the medical model in which disability is seen as a condition inherent in the individual.

Public health historically has used a linear model focusing exclusively on the body functions or dysfunctions of the person and that assumes the person's body dysfunctions and activity limitations are totally responsible for the individual's lack of involvement in the society

Traditionally, because disability has been seen as a problem or an outcome, less attention has been paid to the lives of individuals with impairments or disabilities

Brown (2001) summarizes, the domain of disability has shifted from the old paradigm wherein disability was a medical "problem" involving accessibility, accommodations, and equity to a new paradigm that emphasizes disability as a socio-environmental issue.

For many persons with disabilities, public attitudes, emotions, stigma, stereotypes, lack of access to rehabilitation, and occupational barriers are more limiting than the physical impairment.

Women with disabilities outnumber males in every race and ethnic group except Native Americans in which the gender rates are nearly equal (fans & Stoddard).

As compared to White-Americans, a larger percentage of African-American applicants to the vocational rehabilitation system are denied acceptance. Of the applicants accepted for service, a larger percentage of African-American cases are closed without being rehabilitated.

To be sure, the early days of the Industrial Revolution were rough going, but within a few generations, innovations in technology, medicine, government, and public health led to effective solutions for many of the mismatch diseases caused by the Agricultural Revolution, especially the burden of infectious disease from living at higher population densities with animals and in unsanitary conditions. Not all of these advances, however, are available to people unfortunate enough to live in poverty, especially in less developed nations. In addition, the progress made over the last 150 years has also come with some consequential drawbacks for people’s health. Most essentially, there has been an epidemiological transition. As fewer people succumb to diseases from malnutrition and infections, especially when they are young, more people are developing other kinds of noncommunicable diseases as they age. This transition is still ongoing: in the forty years between 1970 and 2010, the percentage of deaths worldwide from infectious disease and malnutrition fell by 17 percent and life expectancy increased by eleven years, while the percentage of deaths from noncommunicable diseases rose by 30 percent.61 As more people live longer, more of them are suffering from disability. In technical terms, lower rates of mortality have been accompanied by higher rates of morbidity (defined as a state of ill health from any form of disease).

Such narratives were recalled in Canada in 2009 amid public-health responses to the H1N1 epidemic, after federal agencies delivered to rural northern Native communities vaccine and face masks accompanied by unmandated body bags. Outraged community health leaders deplored this as a sign that the very agencies charged with protecting them had given up and were being readied for their deaths. Here, an epidemiological reading that public-health measures cannot prevent epidemic in rural northern Native communities appears as the rationalizing logic of a settler colonial biopolitics.

Oh, and if you’re afraid that the cholesterol in eggs will increase your risk of heart disease, this myth has been thoroughly debunked by both epidemiological and clinicalresearch.4 With

After years of examining the accumulating evidence, eight top health organizations joined forces and agreed to encourage Americans to eat more unrefined plant food and less food from animal sources, as revealed in the dietary guidelines published in the Journal of the American Heart Association. These authorities are the Nutrition Committee of the American Heart Association, the American Cancer Society, the American Academy of Pediatrics, the Council on Cardiovascular Disease in the Young, the Council on Epidemiology and Prevention, the American Dietetic Association, the Division of Nutrition Research of the National Institutes of Health, and the American Society for Clinical Nutrition. Their unified guidelines are a giant step in the right direction. Their aim is to offer protection against the major chronic diseases in America, including heart disease and cancer. “The emphasis is on eating a variety of foods, mostly fruits and vegetables, with very little simple sugar or high-fat foods, especially animal foods,” said

The putative abortion and breast cancer link is a notable example of Internet disinformation. Flawed studies led some authors without medical or epidemiological training to conclude that abortion increases the risk of subsequent breast cancer; large, national studies free of recall bias refute any such link.37,38 Despite the conclusion of objective medical organizations, such as the World Health Organization and the National Cancer Institute, the disinformation campaign is unrelenting.

I am very fortunate to know T. Colin Campbell, PhD, professor emeritus of Cornell University and coauthor of the ground-breaking The China Study. I strongly recommend this book; it’s an expansive and hugely informative work on the effects of food on health. Campbell’s work is regarded by many as the definitive epidemiological examination of the relationship between diet and disease. He has received more than seventy grant years of peer-reviewed research funding (the gold standard of research), much of it from the National Institutes of Health (NIH), and he has authored more than 300 research papers. Dr. Campbell grew up on a dairy farm and believed wholeheartedly in the health value of eating animal protein. Indeed, he set out in his career to investigate how to produce more and better animal protein. Troublesome to his preconceived opinion about the goodness of dairy, Campbell kept running up against results that pointed to a different truth: that animal protein is disastrous to human health. Through a variety of experimental study designs, epidemiological evidence (studies of what affects the illness and health of populations), and observation of real-life conditions that had rational, biological explanations, Dr. Campbell has made a direct and powerful correlation between cancer and animal protein. For this book I asked Dr. Campbell to explain a little about how and why nutrition (both good and bad) affects cancer in our bodies.

Subspecialty : Botany Studies : plants Subspecialty : Zoology Studies : animals Subspecialty : Marine biology Studies : organisms living in and around oceans, and seas Subspecialty : Fresh water biology Studies : organisms living in and around freshwater lakes, streams, rivers, ponds, etc. Subspecialty : Microbiology Studies : microorganisms Subspecialty : Bacteriology Studies : bacteria Subspecialty : Virology Studies : viruses ( see Figure below ) Subspecialty : Entomology Studies : insects Subspecialty : Taxonomy Studies : the classification of organisms Subspecialty : Studies : Life Science : Cell biology What it Examines : cells and their structures (see Figure below ) Life Science : Anatomy What it Examines : the structures of animals Life Science : Morphology What it Examines : the form and structure of living organisms Life Science : Physiology What it Examines : the physical and chemical functions of tissues and organs Life Science : Immunology What it Examines : the mechanisms inside organisms that protect them from disease and infection Life Science : Neuroscience What it Examines : the nervous system Life Science : Developmental biology and embryology What it Examines : the growth and development of plants and animals Life Science : Genetics What it Examines : the genetic make up of all living organisms (heredity) Life Science : Biochemistry What it Examines : the chemistry of living organisms Life Science : Molecular biology What it Examines : biology at the molecular level Life Science : Epidemiology What it Examines : how diseases arise and spread Life Science : What it Examines : Life Science : Ecology What it Examines : how various organisms interact with their environments Life Science : Biogeography What it Examines : the distribution of living organisms (see Figure below ) Life Science : Population biology What it Examines : the biodiversity, evolution, and environmental biology of populations of organisms Life Science : What it Examines :

Both experimental and epidemiological studies show that the driving impairments caused by talking on a cell phone are comparable to the effects of driving while legally intoxicated.

population subsets.

willingness of the scientists to abandon the traditional rules of evidence known as Koch’s postulates. Instead, AIDS researchers, including the ones at the amfAR forum, were willing to “revise Koch’s in a more permissive direction: it would no longer be necessary to find the microbe in all cases of the disease. Mere correlations between microbial antibodies and the progression of the disease would be sufficient. HIV could be proved ‘epidemiologically’ to be the cause of AIDS.” (PBP p.145)

still up at Medium. Again, it’s your alignment that makes you right, not your credentials or the quality of your arguments. Take Knut Wittkowski, for example, one of the victims of YouTube censorship mentioned above. He’s the former head of Biostatistics, Epidemiology and Research Design at Rockefeller University’s Center for Clinical and Translational Science. He has a Ph.D. in computer science from the University of Stuttgart and a Doctor of Science degree in medical biometry from the University of Tübingen, both top German universities. He has as much expertise as anyone from WHO. But he was a staunch critic of the lockdowns and the logic behind them. That made him one of the wrong people.

inherently political and the politics of AIDS science are both antigay and racist. Antigayness and racism are hardwired into the epidemiology and pseudoscience of AIDS in the same way that antisemitism was hardwired into Nazi science. I came up with the term “homodemiology” to describe the kind of antigay epidemiology and science that blames diseases and epidemics on gays and cherry-picks or distorts data to support unwarranted and bigoted conclusions. (“Afrodemiology” is my word for the racist version of the same concept.) In the so-called AIDS epidemic, “public health” is the mask that homodemiology and Afrodemiology wear.

progressives. Nobody expects otherwise. In early May, Knut M. Wittkowski, who specialized in biostatistics and epidemiology for twenty years at Rockefeller University, posted a video on YouTube. He offered sane and sober arguments against the American lockdown. YouTube memory-holed it.20 In April, when Wittkowski first began speaking out, his former employer felt compelled to respond, announcing that his views “do not represent the views of The Rockefeller University, its leadership, or its faculty.”21 Now, that normally goes without saying. We’re not aware of any university that says their faculty speak for it. But in the age of social mania, many universities fear the diverse and critical dialog that used to be the essence of higher education. Evidently, Rockefeller University is one of them.

In early May, Knut M. Wittkowski, who specialized in biostatistics and epidemiology for twenty years at Rockefeller University, posted a video on YouTube. He offered sane and sober arguments against the American lockdown. YouTube memory-holed it.20 In April, when Wittkowski first began speaking out, his former employer felt compelled to respond, announcing that his views “do not represent the views of The Rockefeller University, its leadership, or its faculty.”21 Now, that normally goes without saying. We’re not aware of any university that says their faculty speak for it. But in the age of social mania, many universities fear the diverse and critical dialog that used to be the essence of higher education. Evidently, Rockefeller University is one of them.

In other cases, the reasons for forgetting are more prosaic, more epidemiological, more related to numbers: the particular pandemic disease was not fatal enough (2009 H1N1 influenza), or it did not afflict enough people because it was not infectious enough (MERS), or it burned out too fast (SARS-1), or it afflicted a confined subgroup of the human population (Ebola), or it was brought low by a vaccine (measles and polio), or by treatment (HIV), or by eradication (smallpox), allowing most people to simply push the disease out of their minds. While the way we have come to live in the time of the COVID-19 pandemic might feel alien and unnatural, it is actually neither of those things. Plagues are a feature of the human experience. What happened in 2020 was not new to our species. It was just new to us.

One of the most important problems in epidemiology is to ascertain whether this termination occurs only when no susceptible individuals are left, or whether the interplay of the various factors of infectivity, recovery and mortality, may result in termination, whilst many susceptible individuals are still present in the unaffected population.

The evidence to support cutting out meat consumption is very strong. From studies showing pathophysiologic changes (doctor-speak for “bad stuff happening in the body”) associated with animal consumption that hypothetically could cause heart disease, to epidemiologic studies to randomized control trials, it’s easy to see that the less animal protein, the happier your heart.

Public health was and is where the largest numbers of lives are saved, usually by understanding the epidemiology of a disease—its patterns, where and how it emerges and spreads—and attacking it at its weak points. This usually means prevention. Science had first contained smallpox, then cholera, then typhoid, then plague, then yellow fever, all through large-scale public health measures, everything from filtering water to testing and killing rats to vaccination. Public health measures lack the drama of pulling someone back from the edge of death, but they save lives by the millions.

way stress impedes healing.49 Kiecolt-Glaser and colleagues have also examined how stress affects aging—at the cellular level. At the ends of each of our forty-six chromosomes, which house our DNA, are structures called telomeres. As we age, the telomeres become shorter and shorter. Once they become too short, mistakes start creeping into the way our DNA replicates, which is the leading edge of the aging process. Kiecolt-Glaser points out that there is “ample epidemiological data that stressed caregivers die sooner than people not in that role.” So she and her team compared various elements of the immune response as seen in the blood, as well as telomere lengths in circulating blood cells, in forty-one caregivers and forty-one matched controls.50 As you might suspect, not only was immune function off in the caregivers, but their telomeres were shorter. This shows that stress can age people at the very level of their cells, thereby potentially shaving years off their lives.

Epidemiological evidence suggests that a new influenza virus originated in Haskell County, Kansas, early in 1918. Evidence further suggests that this virus traveled east across the state to a huge army base, and from there to Europe. Later it began its sweep through North America, through Europe, through South America, through Asia and Africa, through isolated islands in the Pacific, through all the wide world. In its wake followed a keening sound that rose from the throats of mourners like the wind. The evidence comes from Dr. Loring Miner.

More generally, religious pilgrimages rivaled warfare in provoking epidemic infection. The doctrine that disease came from God could easily be interpreted to mean that it was impious to interfere with God's purposes by trying to take conscious precaution against disease, either in war or on pilgrimage. Part of the meaning of pilgrimage was the taking of risks in pursuit of holiness. To die en route was, for the pious, and act of God whereby He deliberately translated the pilgrim from the hardships of life on earth into His presence. Disease and pilgrimage were thus psychologically as well as epidemiologically complementary. The same may be said of war, where risk of sudden death -one's own or the enemy's- was at the very core of the enterprise.

But influenza is not simply a bad cold. It is a quite specific disease, with a distinct set of symptoms and epidemiological behavior. In humans the virus directly attacks only the respiratory system, and it becomes increasingly dangerous as it penetrates deeper into the lungs. Indirectly it affects many parts of the body, and even a mild infection can cause pain in muscles and joints, intense headache, and prostration.

Epidemiological evidence suggests that a new influenza virus originated in Haskell County, Kansas, early in 1918. Evidence further suggests that this virus traveled east across the state to a huge army base, and from there to Europe. Later it began its sweep through North America, through Europe, through South America, through Asia and Africa, through isolated islands in the Pacific, through all the wide world.

Epidemiological evidence suggests that a new influenza virus originated in Haskell County, Kansas, early in 1918. Evidence further suggests that this virus traveled east across the state to a huge army base, and from there to Europe. Later it began its sweep through North America, through Europe, through South America, through Asia and Africa, through isolated islands in the Pacific, through all the wide world. In its wake followed a keening sound that rose from the throats of mourners like the wind.

There are three essentials for good public health programs. The first is the conviction that the basis for public health is to achieve health equity; therefore, the bottom line is social justice in health. Second is the understanding that the science base is epidemiology. It is epidemiology that determines the gaps in social justice, identifies the groups with poor health outcomes, discovers the details of disease causation, and provides clues to how corrective action might improve health. The third essential is the need for good management for efficient implementation of corrective actions.

... When infectious diseases lost their hold as the major causes of death, the industrialised world underwent a shift, known as the 'epidemiological transition' and chronic diseases, such as heart disease and cancer, replaced infections as the major causes of death and poor health.

The medical basis for the preventorium was a new understanding of the epidemiology of tuberculosis made possible by Koch’s tuberculin skin test.

Epidemiological evidence suggests that a new influenza virus originated in Haskell County, Kansas, early in 1918. Evidence further suggests that this virus traveled east across the state to a huge army base, and from there to Europe. Later it began its sweep through North America, through Europe, through South America, through Asia and Africa, through isolated islands in the Pacific, through all the wide world. In its wake followed a keening sound that rose from the throats of mourners like the wind. The evidence comes from Dr. Loring Miner. •

Ironically, given the high-tech quality of the diagnostic and monitoring effort, the containment policies were based on traditional methods dating from the public health strategies against bubonic plague of the seventeenth century and the foundation of epidemiology as a discipline in the nineteenth century—case tracking, isolation, quarantine, the cancellation of mass gatherings, the surveillance of travelers, recommendations to increase personal hygiene, and barrier protection by means of masks, gowns, gloves, and eye protection. Although SARS affected twenty-nine countries and five continents, the containment operation successfully limited the outbreak primarily to hospital settings, with only sporadic community involvement. By July 5, 2003, WHO could announce that the pandemic was over.

Until the Indian Plague Commission in 1908–1909 established the complex role of rats and fleas, the epidemiology of the disease therefore remained a mystery.

A common feature of epidemiological data is that they are almost certain to be biased, of doubtful quality, or incomplete (and sometimes all three),” explained the epidemiologist John Bailar in The New England Journal of Medicine in 1980. “Problems do not disappear even if one has flawless data, since the statistical associations in almost any nontrivial set of observations are subject to many interpretations. This ambiguity exists because of the difficulty of sorting out causes, effects, concomitant variables, and random fluctuations when the causes are multiple or diffuse, the exposure levels low, irregular, or hard to measure, and the relevant biologic mechanisms poorly understood. Even when the data are generally accepted as accurate, there is much room for individual judgment, and the considered conclusions of the investigators on these matters determine what they will label ‘cause’…

Inhabitants of isolated or remote regions where there has been little or no contact with the outside world are often described as “epidemiologically naive.” What this means is that they have limited immunity to diseases like influenza and measles that are endemic in other parts of the world, and when exposed to them they often suffer high rates of death. One of the best-known examples comes from the pandemic of 1918, in which certain populations, notably indigenous Alaskans and Pacific Islanders, died at rates that were four, five, and in some cases even ten times those of other populations. The pandemic is thought to have killed between 3 and 6 percent of the global population; in Western Samoa, 20 percent of the population died. In the nineteenth-century Pacific, this scenario played itself out over and over.

Based on epidemiological studies of average sleep time, millions of individuals unwittingly spend years of their life in a sub-optimal state of psychological and physiological functioning, never maximizing their potential of mind or body due to their blind persistence in sleeping too little.

Widening the lens of focus, there are more than twenty large-scale epidemiological studies that have tracked millions of people over many decades, all of which report the same clear relationship: the shorter your sleep, the shorter your life. The leading causes of disease and death in developed nations—diseases that are crippling health-care systems, such as heart disease, obesity, dementia, diabetes, and cancer—all have recognized causal links to a lack of sleep.

Global poverty is half what it was twenty years ago. Violent crimes have abated dramatically in the US, declining from 1993’s high of 79.8 victims per thousand people to our current level of 23.2.2 Per the American Journal of Epidemiology, DUIs are down, likely thanks to chatty drunks opting for rideshare services.3 Bottom line? The data supports that these are the best of times. So . . . why the hell does it feel like the end of days? Why does it seem like it’s about to rain locusts?

Epidemiology

FDA used the same playbook in 2002 to isolate, silence, and drive from government service its star epidemiologist, Dr. Bart Classen, when his massive epidemiologic studies, the largest ever performed, linked Hib vaccines to the juvenile diabetes epidemic. FDA ordered Dr. Classen to refrain from publishing the government-funded studies, forbade him from talking publicly about the alarming outbreak, and eventually forced him out of government service.

Columbus’s fateful voyage was inspired by his study of a map by Paolo Toscanelli. But there was also the 1854 cholera outbreak in London, which killed hundreds of people until a physician, John Snow, drew a map demonstrating that a single contaminated water pump was the source of the illness, thereby founding the science of epidemiology. There was the 1944 invasion at Normandy, which succeeded only because of the unheralded contribution of mapmakers who had stolen across the English Channel by night for months before D-Day and mapped the French beaches.* Even the moon landing was a product of mapping. In 1961, the United States Geological Survey founded a Branch of Astrogeology, which spent a decade painstakingly assembling moon maps to plan the Apollo missions. The Apollo 11 crew pored over pouches of those maps as their capsule approached the lunar surface, much as Columbus did during his voyage. It seems that the greatest achievements in human history have all been made possible by the science of cartography.

In most cases, the infection is asymptomatic and the patient is unaware of its presence. It is critical to the epidemiology of polio, however, that such people nevertheless shed the virus and function as asymptomatic carriers.

the process of reverse transcription is central to the epidemiology of HIV/AIDS because it is highly prone to error. Thus it causes mutations with great frequency, creating varieties, or “clades,” of HIV and underlying the development of drug resistance.

Snow published his findings and the maps that illustrated them in his major work of 1855 On the Mode of Communication of Cholera, which is now widely considered the foundational text of epidemiology as a discipline. During Snow’s lifetime, although the book kept the emerging germ theory in public view, it failed to persuade the medical profession. Anticontagionism and miasmatism persisted as orthodoxy with regard to cholera.