Embryo Transfer Day Quotes

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It is undignified to inject yourself with hormones designed to slow or enhance ovarian production. It is undignified to have your ovaries monitored by transvaginal ultrasound; to be sedated so that your eggs can be aspirated into a needle; to have your husband emerge sheepishly from a locked room with the β€œsample” that will be combined with your eggs under supervision of an embryologist. The grainy photo they hand you on transfer day, of your eight-celled embryo (which does not look remotely like a baby), is undignified, and so is all the waiting and despairing that follows.
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Belle Boggs (The Art of Waiting: On Fertility, Medicine, and Motherhood)
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Can embryo fall out of the uterus after its transfer? IVF is a complicated assisted reproductive technique, which not only has the patients spend a lot but also takes an emotional toll. The two week wait period after the implantation of the embryo seems to be like a roller coaster ride time for the couples, as it seems to decide the fate of the cycle. As the embryo is transferred into the uterus by artificial means, the biggest fear that plagues the couple is that it might fall out of the uterus after the transfer. The fear might be so great that normal activities like standing up, walking, having sex, peeing, coughing, sneezing and laughing might be seen as sinful ones by the prospective parents. Though people without medical background are justified in thinking that embryo can make its way out from the same route it went in, thankfully, the apprehension is baseless. For understanding why you need not be scared of such a possibility, it is necessary to comprehend how things actually work when the embryo implants itself into the uterus and what happens after that. What happens during and after embryo transfer? The primary step of IVF is embryo culture, during which eggs are combined with sperms in a lab dish and made to reach the embryo stage (a 3 day or 5 day culture depending upon the clinic protocol). The best amongst the cultured embryos is selected for uterine transfer. The embryologist first takes out the chosen embryo from the incubator and then transfers the same into the uterine cavity with the help of a thin and soft catheter. The right placement of embryo is ensured by using ultrasound guidance as the catheter is threaded through the cervix. Once the embryo is transferred into the uterus, the patient is generally made to lie on her back for an hour or so. Since the process is ultrasound guided, the same is done with full bladder as a protocol of the scanning procedure. This means that the patient would need to urinate at the end of the transfer. Scary as it may sound, peeing after the transfer would not flush out the embryo from the uterus. Though the doctors would not stop you from standing and doing all normal activities after the transfer, strenuous workout and lifting heavy objects need to be avoided and so do hot baths and Jacuzzis. During the two week wait, the woman needs to abstain from smoking, alcohol, caffeine and all other potential threats to the pregnancy. Though best efforts are made for choosing the healthiest amongst the embryos and ensuring its proper placement during the IVF, nature takes its course once the transfer has been done. Nothing can be done to influence the implantation of the embryo in the uterus, as it takes some time to develop and stick to the uterine walls and will do it successfully if it is meant to. Is it possible for the embryo to fall out of the uterus? The uterus can be pictured as a cavity, an empty space, within which the embryo(s) would be deposited and would roll around as the woman would stand up and walk around. In fact, it is quite possible for the woman to be obsessed about taking bed rest to maximize the chances of the embryo settling down and sticking to the uterine walls. The truth, however, is that the uterus is a potential cavity rather than a true one. It is a muscular organ, which originally has its walls touching each other and it increases in size as the embryo grows. So practically, the tiny embryo would have a snug fit within the uterine walls and there is no chance that it would get dislodged and fall out. For a woman with receptive endometrial lining and healthy embryo, there is hardly a reason why pregnancy would not take place. No external influence such as exercise, walking or sneezing can interfere with the process of the embryo sticking to the wall. This is the miracle of nature which cannot be matched even by the most amazing innovations in science and technology.
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gaudiumivfcentre
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Embryo Culture: Are my embryos in safe hands? Pregnancy starts with the fertilization of an egg with a sperm to form an embryo, which implants itself to the uterine lining. Therefore, it would not be wrong to say that the embryo is the building block of pregnancy, whether natural or assisted. In context of the commonly used artificial reproductive technique IVF, embryo culture implies the formation of zygote and its growth into a embryo. IVF starts with egg retrieval from the ovaries of the patient and these eggs are fertilized with sperms to form a zygote. The zygote is then allowed to grow by placing it in an artificial medium and under favorable conditions. The growth of zygote into embryo, or embryo culture, takes 2 to 5 days to be completed. The embryo is then placed into the uterus for the pregnancy to continue in the normal manner. The success of IVF greatly depends upon the conditions made available for embryo culture, because it is actually a healthy embryo which generates a healthy pregnancy. Therefore, IVF patients need to ensure that the procedure of embryo culture should be carried out to perfection and the embryos remain safe while they are in the lab, before being transferred to the uterus. Understanding Embryo Culture- The Procedure Embryo culture is one of the most vital and delicate steps involved in IVF as it requires a great degree of skill and expertise to be completed successfully. A process of 2 to 5 days, it is carried out in a series of steps. Fertilization: The Formation of Zygote The procedure begins as soon as the follicular fluid is aspirated from the ovaries of the patient. It is carried to the lab, where the embryologist makes its microscopic examination for identifying the eggs present in it. A special medium is used to wash away the toxins as well as impurities around the egg and the surrounding cells. From here, they are taken into carbon dioxide filled incubators, where they are placed in separate dishes. The eggs are then allowed to mature for fertilization, a process taking 2-6 hours in all. Once the eggs are mature for fertilization, they are made to combine with the male sperms, which too have been washed. This process is carried out in a dish which contains a culture medium, a fluid comprising of salt, proteins and antibiotics. This medium, known as Human Tubal Fluid (HTF) medium, is specially formulated to facilitate the cell division and fulfill the metabolic needs of the growing embryo. Once set for fertilization, the dish makes it way back into the incubator. Monitoring of the Embryos Embryo culture is not just about synthesis of the embryos in the lab, but they also have to be monitored carefully to ensure their quality. The embryo requires a controlled environment to grow and flourish into a healthy one and has to be monitored carefully by a qualified embryologist. The next growth milestone is achieved by the embryo after a period of 18 hours. The stage reached is called the pronuclei stage and it is characterized by the formation of two clear bubbles in the embryo. This is the time where the embryologist discards the embryos without the pronunlei. The embryos are given another 24 hours to develop and from here on, monitoring is done for cell division. This is the time when the embryos would divide into two to four cells (cleavage stage which comes after 2-4 days), a stage considered favorable for the implant by some clinics. On the other hand, some clinics transfer the embryos later, when they reach the blastocyst stage (after 5 days). The decision is based on factors like the health conditions of the patients and the protocol followed by the clinic. What is the right time duration of embryo culture? Another factor which is used to determine the success rate of embryo culture and the safety of the embryos in the lab is the time duration of the procedure. Basically, it can vary from patient to patient, depending upon the reproductive history of both the partners.
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gaudiumivfcentre