Dna Key Quotes

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Somewhere in our DNA must lie the key mutation (or, more probably, mutations) that set us apart—the mutations that make us the sort of creature that could wipe out its nearest relative, then dig up its bones and reassemble its genome.
Elizabeth Kolbert (The Sixth Extinction: An Unnatural History)
Our choices—the natural consequences of our thoughts and imagination—get “under the skin” of our DNA and can turn certain genes on and off, changing the structure of the neurons in our brains. So our thoughts, imagination, and choices can change the structure and function of our brains on every level:
Caroline Leaf (Switch On Your Brain: The Key to Peak Happiness, Thinking, and Health)
The fact is that when the frequency of your DNA hits the Schumann Resonance, your experience of time stops completely. These are truths that are still experienced and embodied by many of the indigenous cultures alive on our planet today. To live closely to the earth’s natural rhythms is to experience the wisdom and clarity that comes of moving more slowly through the world.
Richard Rudd (The Gene Keys: Embracing Your Higher Purpose)
We are all made from chromosomes and DNA, which themselves are made from a select handful of key elements. We all require a steady intake of water and oxygen to survive (though in varying quantities). We all need food. We all buckle under atmospheres too thick or gravitational fields too strong. We all die in freezing cold or burning heat. We all die, full stop.
Becky Chambers (The Long Way to a Small, Angry Planet (Wayfarers, #1))
What all of this means is that you can never be a victim of your DNA. Neither can you be a victim of fate. You can only be a victim of your attitude.
Richard Rudd (The Gene Keys: Embracing Your Higher Purpose)
Shamanism resembles an academic discipline (such as anthropology or molecular biology); with its practitioners, fundamental researchers, specialists, and schools of thought it is a way of apprehending the world that evolves constantly. One thing is certain: Both indigenous and mestizo shamans consider people like the Shipibo-Conibo, the Tukano, the Kamsá, and the Huitoto as the equivalents to universities such as Oxford, Cambridge, Harvard, and the Sorbonne; they are the highest reference in matters of knowledge. In this sense, ayahuasca-based shamanism is an essentially indigenous phenomenon. It belongs to the indigenous people of Western Amizonia, who hold the keys to a way of knowing that they have practiced without interruption for at least five thousand years. In comparison, the universities of the Western world are less than nine hundred years old.
Jeremy Narby (The Cosmic Serpent: DNA and the Origins of Knowledge)
What you are thinking every moment of every day becomes a physical reality in your brain and body, which affects your optimal mental and physical health. These thoughts collectively form your attitude, which is your state of mind, and it’s your attitude and not your DNA that determines much of the quality of your life.
Caroline Leaf (Switch On Your Brain: The Key to Peak Happiness, Thinking, and Health)
Science has discovered that, like any work of literature, the human genome is a text in need of commentary, for what Eliot said of poetry is also true of DNA: 'all meanings depend on the key of interpretation.' What makes us human, and what makes each of us his or her own human, is not simply the genes that we have buried into our base pairs, but how our cells, in dialogue with our environment, feed back to our DNA, changing the way we read ourselves. Life is a dialectic.
Jonah Lehrer (Proust Was a Neuroscientist)
This is the higher purpose hidden in all human DNA — to hit the speed of Being.
Richard Rudd (The Gene Keys: Embracing Your Higher Purpose)
Ancient DNA has established major migration and mixture between highly divergent populations as a key force shaping human prehistory, and ideologies that seek a return to a mythical purity are flying in the face of hard science.
David Reich (Who We Are and How We Got Here: Ancient DNA and the new science of the human past)
Chapter 1 Summary The debate in science is between the mind being what the brain does versus the brain doing the bidding of the mind. The correct view is that the mind is designed to control the body, of which the brain is a part, not the other way around. Our brain does not control us; we control our brain through our thinking and choosing. We can control our reactions to anything. Choices are real. You are free to make choices about how you focus your attention, and this affects how the chemicals, proteins, and wiring of your brain change and function. Research shows that DNA actually changes shape in response to our thoughts. Stress stage one is normal. Stress stage two and stage three, on the other hand, are our mind and body’s response to toxic thinking—basically normal stress gone wrong. Reaction is the key word here. You cannot control the events or circumstances of your life, but you can control your reactions.
Caroline Leaf (Switch On Your Brain: The Key to Peak Happiness, Thinking, and Health)
The key point here is that large companies typically fail at disruptive innovation because the top management team is dominated by individuals who have been selected for delivery skills, not discovery skills. As a result, most executives at large organizations don’t know how to think different. It isn’t something that they learn within their company, and it certainly isn’t something they are taught in business school. Business schools teach people how to be deliverers, not discoverers.
Clayton M. Christensen (The Innovator's DNA: Mastering the Five Skills of Disruptive Innovators)
It also showed that the only real block to bi-maternal reproduction is the DNA methylation pattern at key genes. It disproved a previous hypothesis that sperm were required because the sperm themselves carried certain necessary accessory factors such as particular proteins or RNA molecules required to kick-start development properly.16
Nessa Carey (Junk DNA: A Journey Through the Dark Matter of the Genome)
Every now and then, you find a book that feels like it was keyed to your DNA.
Alexander Chee
Eric R. Kandel, a Nobel Prize–winning neuropsychiatrist for his work on memory, shows how our thoughts, even our imaginations, get “under the skin” of our DNA and can turn certain genes on and certain genes off, changing the structure of the neurons in the brain.[1] So as we think and imagine, we change the structure and function of our brains. Even Freud speculated back in the 1800s that thought leads to changes in the brain.[2] In recent years, leading neuroscientists like Marion Diamond, Norman Doidge, Joe Dispenza, Jeffrey Schwartz, Henry Markram, Bruce Lipton, and Allan Jones, to name just a few, have shown how our thoughts have remarkable power to change the brain.[3] Our brain is changing moment by moment as we are thinking. By our thinking and choosing, we are redesigning the landscape of our brain.
Caroline Leaf (Switch On Your Brain: The Key to Peak Happiness, Thinking, and Health)
Consider a resident of Berlin, born in 1900 and living to the ripe age of one hundred. She spent her childhood in the Hohenzollern Empire of Wilhelm II; her adult years in the Weimar Republic, the Nazi Third Reich and Communist East Germany; and she died a citizen of a democratic and reunified Germany. She had managed to be a part of five very different sociopolitical systems, though her DNA remained exactly the same. This was the key to Sapiens’ success.
Yuval Noah Harari (Sapiens: A Brief History of Humankind)
The real key to human gene mapping, Botstein had realized, was not finding the gene, but finding the humans. If a large-enough family bearing a genetic trait-any trait-could be found, and if that trait could be correlated with any of the variant markers spread across the genome, then gene mapping would become a trivial task. If all the members of a family affected by cystic fibrosis inevitably "co-inherited" some variant DNA marker, call it Variant-X, located on the tip of chromosome seven, then the cystic fibrosis gene had to sit in proximity to this location.
Siddhartha Mukherjee (The Gene: An Intimate History)
Biochemist David Goodsell describes the problem, “The key molecular process that makes modern life possible is protein synthesis, since proteins are used in nearly every aspect of living. The synthesis of proteins requires a tightly integrated sequence of reactions, most of which are themselves performed by proteins.”41 Or as Jacques Monod noted in 1971: “The code is meaningless unless translated. The modern cell’s translating machinery consists of at least fifty macromolecular components which are themselves coded in DNA: the code cannot be translated otherwise than by products of
Stephen C. Meyer (Signature in the Cell: DNA and the Evidence for Intelligent Design)
As more and more data flows from your body and brain to the smart machines via the biometric sensors, it will become easy for corporations and government agencies to know you, manipulate you, and make decisions on your behalf. Even more importantly, they could decipher the deep mechanisms of all bodies and brains, and thereby gain the power to engineer life. If we want to prevent a small elite from monopolising such godlike powers, and if we want to prevent humankind from splitting into biological castes, the key question is: who owns the data? Does the data about my DNA, my brain and my life belong to me, to the government, to a corporation, or to the human collective?
Yuval Noah Harari (21 Lessons for the 21st Century)
What is that 95 percent? Some is junk—remnants of pseudogenes inactivated by evolution.fn4,3 But buried in that are the keys to the kingdom, the instruction manual for when to transcribe particular genes, the on/off switches for gene transcription. A gene doesn’t “decide” when to be photocopied into RNA, to generate its protein. Instead, before the start of the stretch of DNA coding for that gene is a short stretch called a promoterfn5—the “on” switch. What turns the promoter switch on? Something called a transcription factor (TF) binds to the promoter. This causes the recruitment of enzymes that transcribe the gene into RNA. Meanwhile, other transcription factors deactivate genes.
Robert M. Sapolsky (Behave: The Biology of Humans at Our Best and Worst)
[I]nclusion, not assimilation, should be the key concept in seeking, ever seeking, a more perfect national union. Our own history has shown that we are stronger as a mosaic than a melting pot. Our nation is bound together more by ideals than by blood or land, and inclusion is in our cultural DNA. We should feel proud that we are not all the same, and that we can share our differences under the common umbrella of humanity.
Dan Rather (What Unites Us: Reflections on Patriotism)
Al Hershey had sent me a long letter from Cold Spring Harbor summarizing the recently completed experiments by which he and Martha Chase established that a key feature of the infection of a bacterium by a phage was the injection of the viral DNA into the host bacterium. Most important, very little protein entered the bacterium. Their experiment was thus a powerful new proof that DNA is the primary genetic material. Nonetheless, almost no one in the audience of over four hundred microbiologists seemed interested as I read long sections of Hershey’s letter. Obvious exceptions were André Lwoff, Seymour Benzer, and Gunther Stent, all briefly over from Paris. They knew that Hershey’s experiments were not trivial and that from then on everyone was going to place more emphasis on DNA. To most of the spectators, however, Hershey’s name carried no weight.
James D. Watson (The Double Helix: A Personal Account of the Discovery of the Structure of DNA)
Consider a resident of Berlin, born in 1900 and living to the ripe age of one hundred. She spent her childhood in the Hohenzollern Empire of Wilhelm II; her adult years in the Weimar Republic, the Nazi Third Reich and Communist East Germany; and she died a citizen of a democratic and reunified Germany. She had managed to be a part of five very different sociopolitical systems, though her DNA remained exactly the same. This was the key to Sapiens’ success. In a one-on-one brawl, a Neanderthal would probably have beaten a Sapiens. But in a conflict of hundreds, Neanderthals wouldn’t stand a chance. Neanderthals could share information about the whereabouts of lions, but they probably could not tell – and revise – stories about tribal spirits. Without an ability to compose fiction, Neanderthals were unable to cooperate effectively in large numbers, nor could they adapt their social behaviour to rapidly changing challenges.
Yuval Noah Harari (Sapiens: A Brief History of Humankind)
The basic elements of DNA—hydrogen, nitrogen, oxygen, and carbon—translate directly to key letters of the Hebrew and Arabic alphabets. In these languages, our genetic code spells the ancient name of God. The same name lives within all humans, regardless of their beliefs, actions, lifestyle, religion, or heritage. This relationship was described in sacred texts, such as the Hebrew Sepher Yetzirah, at least 1,000 years before modern science verified such connections.
Gregg Braden (The God Code: The Secret of Our Past, the Promise of Our Future)
Frequency is translated into chemistry. The vibratory pitch of your attitude at any given moment is transferred to your DNA and quickly becomes your reality. Knowing this you have the freedom to choose how you design your life. It is you who designs your own health, your own relationships, and your own inner fulfilment. The second golden rule comes in the form of another caution; that we need to be very careful about using our knowledge (consciously or unconsciously) as a weapon. In our relationships we can all too easily point out the Shadows of others. Our ego can get a hold of knowledge and use it to try and help someone else, when in fact your urge to help the other has become a distraction from your own process. If you wish to truly help others, then you would do best to forget their Shadows altogether and contemplate their Gifts and Siddhis. If they are caught in a Shadow pattern then give them the frequency of their Siddhi as a response. Model the higher frequencies of others for others. The Shadows are for you alone!
Richard Rudd (Love: A guide to your Venus Sequence (The Gene Keys Golden Path Book 2))
The incredible specified complexity of life becomes obvious when one considers the message found in the DNA of a one-celled amoeba (a creature so small, several hundred could be lined up in an inch). Staunch Darwinist Richard Dawkins, professor of zoology at Oxford University, admits that the message found in just the cell nucleus of a tiny amoeba is more than all thirty volumes of the Encyclopedia Britannica combined, and the entire amoeba has as much information in its DNA as 1,000 complete sets of the Encyclopedia Britannica!2 In other words, if you were to spell out all of the A, T, C, and G in the unjustly called primitive amoeba (as Dawkins describes it), the letters would fill 1,000 complete sets of an encyclopedia! Now, we must emphasize that these 1,000 encyclopedias do not consist of random letters but of letters in a very specific orderjust like real encyclopedias. So heres the key question for Darwinists like Dawkins: if simple messages such as Take out the garbageMom, Mary loves Scott, and Drink Coke require an intelligent being, then why doesnt a message 1,000 encyclopedias long require one?
Norman L. Geisler (I Don't Have Enough Faith to Be an Atheist)
The key of brotherhood and sisterhood is that brothers and sisters carry the same genetic code. Together, united, they carry the legacy of their forefathers. Our bond (through our shared blood/DNA) as Ba Ga Mohlala family/clan is our insurance for the future. As Ba Ga Mohlala we can have our own Law firms, Auditing Firms, Doctors's Medical Surgeries, Private School, Private Clinics or Private Hospital, farms and lot of small to medium manufacturing, service, retail and wholesale companies and become self relient. All it takes to achieve that is unity, willpower and commitment.
Pekwa Nicholas Mohlala
while the behaviour patterns of archaic humans remained fixed for tens of thousands of years, Sapiens could transform their social structures, the nature of their interpersonal relations, their economic activities and a host of other behaviours within a decade or two. Consider a resident o Berlin, born in 1900 and living to the ripe age of one hundred. She spent her childhood in the Hohenzollern Empire of Wilhelm II; her adult years in the Weimar Republic, the Nazi Third Reich and Communist East Germany; and she died a citizen of a democratic and reunified Germany. She had managed to be a part of five very different sociopolitical systems, though her DNA remained exactly the same. This was the key to Sapiens' success. In a one-on-one brawl, a Neanderthal would probably have beaten a Sapiens. But in a conflict of hundreds, Neanderthals wouldn't stand a chance. Neanderthals could share information about the whereabouts of lions, but they probably could not tell - and revise - stories about tribal spirits. Without an ability to compose fiction, Neanderthals were unable to cooperate effectively in large numbers, nor could they adapt their social behaviour to rapidly changing challenging. (p. 38)
Yuval Noah Harari (Sapiens: A Brief History of Humankind)
That's the beauty of discipline. It trumps everything. A lot of us are born with minimal talent, unhappy in our own skin and with the genetic makeup with which we were born. We have fucked-up parents, grow up bullied and abused, or are diagnosed with learning disabilities. We hate our hometown, our teachers, our families, and damn near everything about ourselves. We wish we could be born again as some other motherfucker in some other time and place. Well, I am proof that rebirth is possible through discipline, which is the only thing capable of altering your DNA. It is the skeleton key that can get you past all the gatekeepers and into each and every room you wish to enter. Even the ones built to keep you the fuck out! ... Discipline builds mental endurance because when effort is your main priority, you stop looking for everything to be enjoyable. Our phones and social media have turned too many of us inside out with envy and greed as we get inundated with other people's success, their new cars and houses, big contracts, resort vacations, and romantic getaways. We see how much fun everyone else is having and feel like the world is passing us by, so we bitch about it and then wonder why we are not where we want to be. When you become disciplined, you don't have time for that bullshit. p140
David Goggins (Never Finished: Unshackle Your Mind and Win the War Within)
The key point is that these patterns, while mostly stable, are not permanent: certain environmental experiences can add or subtract methyls and acetyls, changing those patterns. In effect this etches a memory of what the organism was doing or experiencing into its cells—a crucial first step for any Lamarck-like inheritance. Unfortunately, bad experiences can be etched into cells as easily as good experiences. Intense emotional pain can sometimes flood the mammal brain with neurochemicals that tack methyl groups where they shouldn’t be. Mice that are (however contradictory this sounds) bullied by other mice when they’re pups often have these funny methyl patterns in their brains. As do baby mice (both foster and biological) raised by neglectful mothers, mothers who refuse to lick and cuddle and nurse. These neglected mice fall apart in stressful situations as adults, and their meltdowns can’t be the result of poor genes, since biological and foster children end up equally histrionic. Instead the aberrant methyl patterns were imprinted early on, and as neurons kept dividing and the brain kept growing, these patterns perpetuated themselves. The events of September 11, 2001, might have scarred the brains of unborn humans in similar ways. Some pregnant women in Manhattan developed post-traumatic stress disorder, which can epigenetically activate and deactivate at least a dozen genes, including brain genes. These women, especially the ones affected during the third trimester, ended up having children who felt more anxiety and acute distress than other children when confronted with strange stimuli. Notice that these DNA changes aren’t genetic, because the A-C-G-T string remains the same throughout. But epigenetic changes are de facto mutations; genes might as well not function. And just like mutations, epigenetic changes live on in cells and their descendants. Indeed, each of us accumulates more and more unique epigenetic changes as we age. This explains why the personalities and even physiognomies of identical twins, despite identical DNA, grow more distinct each year. It also means that that detective-story trope of one twin committing a murder and both getting away with it—because DNA tests can’t tell them apart—might not hold up forever. Their epigenomes could condemn them. Of course, all this evidence proves only that body cells can record environmental cues and pass them on to other body cells, a limited form of inheritance. Normally when sperm and egg unite, embryos erase this epigenetic information—allowing you to become you, unencumbered by what your parents did. But other evidence suggests that some epigenetic changes, through mistakes or subterfuge, sometimes get smuggled along to new generations of pups, cubs, chicks, or children—close enough to bona fide Lamarckism to make Cuvier and Darwin grind their molars.
Sam Kean (The Violinist's Thumb: And Other Lost Tales of Love, War, and Genius, as Written by Our Genetic Code)
Staying at Home during this lockdown period is the right time to find your life purpose within Ba Ga Mohlala family/clan. This is an opportunity to know yourself better and to understand what motivates and feeds your mind and your soul, and also to find out as to where you fit in the bigger Ba Ga Mohlala family/clan. All members of each family/clan possess characteristics, abilities, and qualities specific to that family/clan. It is up to the family/clan to distinguish itself amongst other families/clans. Ba Ga Mohlala has become an institution to build cooperation in order to build and forge unity for social and economic benefits for Ba Ga Mohlala and Banareng in general. An institution is social structure in which people cooperate and which influences the behavior of people and the way they live. intelligence and assertiveness comes to us as our nature, it is in our blood (DNA) and all there is for us to do is to nature it and it will shine, otherwise it will gather dust and rust in us. The key of brotherhood and sisterhood is that brothers and sisters carry the same genetic code. Together, united, they carry the legacy of their forefathers. Our bond (through our shared blood/DNA) as Ba Ga Mohlala family/clan is our insurance for the future. As Ba Ga Mohlala we can have our own Law firms, Auditing Firms, Doctors's Medical Surgeries, Private School, Private Clinics or Private Hospital, farms and lot of small to medium manufacturing, service, retail and wholesale companies and become self relient. All it takes to achieve that is unity, willpower and commitment.
Pekwa Nicholas Mohlala
Braid groups have many important practical applications. For example, they are used to construct efficient and robust public key encryption algorithms.7 Another promising direction is designing quantum computers based on creating complex braids of quantum particles known as anyons. Their trajectories weave around each other, and their overlaps are used to build “logic gates” of the quantum computer.8 There are also applications in biology. Given a braid with n threads, we can number the nails on the two plates from 1 to n from left to right. Then, connect the ends of the threads attached to the nails with the same number on the two plates. This will create what mathematicians call a “link”: a union of loops weaving around each other. In the example shown on this picture, there is only one loop. Mathematicians’ name for it is “knot.” In general, there will be several closed threads. The mathematical theory of links and knots is used in biology: for example, to study bindings of DNA and enzymes.9 We view a DNA molecule as one thread, and the enzyme molecule as another thread. It turns out that when they bind together, highly non-trivial knotting between them may occur, which may alter the DNA. The way they entangle is therefore of great importance. It turns out that the mathematical study of the resulting links sheds new light on the mechanisms of recombination of DNA. In mathematics, braids are also important because of their geometric interpretation. To explain it, consider all possible collections of n points on the plane. We will assume that the points are distinct; that is, for any two points, their positions on the plane must be different. Let’s choose one such collection; namely, n points arranged on a straight line, with the same distance between neighboring points. Think of each point as a little bug. As we turn on the music, these bugs come alive and start moving on the plane. If we view the time as the vertical direction, then the trajectory of each bug will look like a thread. If the positions of the bugs on the plane are distinct at all times – that is, if we assume that the bugs don’t collide – then these threads will never intersect. While the music is playing, they can move around each other, just like the threads of a braid. However, we demand that when we stop the music after a fixed period of time, the bugs must align on a straight line in the same way as at the beginning, but each bug is allowed to end up in a position initially occupied by another bug. Then their collective path will look like a braid with n threads. Thus, braids with n threads may be viewed as paths in the space of collections of n distinct points on the plane.10
Edward Frenkel (Love and Math: The Heart of Hidden Reality)
The stuff of life, in other words, arose in places and times somewhat more accessible to our telescopic investigations. Since most of us spend our lives confined to a narrow strip near Earth’s surface, we tend to think of the cosmos as a lofty, empyrean realm far beyond our reach and relevance. We forget that only a thin sliver of atmosphere separates us from the rest of the universe. But science continues to show just how intimately connected life on Earth is to extraterrestrial processes. In particular, several recent findings have further illuminated the cosmic origins of life’s key ingredients. Take the element phosphorus, for example. It is a critical constituent of DNA, as well as of our cells, teeth and bones. Astronomers have long struggled to trace its buildup through cosmic history, because the imprint of phosphorus is difficult to discern in old, cool stars in the outskirts of our galaxy. (Some of these stellar “time capsules” contain the ashes of their forebears, the very first generation of stars that formed near the dawn of time.) But in a paper published in December in The Astrophysical Journal Letters, a research team reported that it had measured the abundance of phosphorus in 13 such stars, using data taken with the Hubble Space Telescope. Their findings highlight the dominant role of so-called hypernovae, explosions even more energetic than supernovae that spell the demise of massive stars, in making the elements
Anonymous
We human beings are following different vectors through time and space and each of our paths must at some time converge at this single point deep inside the body. There is a place inside your DNA whose sole purpose is to trigger this awakening.
Richard Rudd (The Gene Keys: Embracing Your Higher Purpose)
Ancel Keys conducted research on the diets of people from 22 countries to observe the relationship between cholesterol intake and cardiovascular disease. He started publishing results as of 1955. In his findings however, he only presented data from 7 countries that proved a linear relationship (apparently causal) between the two parameters.                 When other researchers started accessing the same databases that Keys did, and when they plugged-in the data from all 22 countries, they observe no relationship between cholesterol intake and heart disease whatsoever [70]. But it was too late at that point, because the harm was made. Keys gained a lot of influence and may have participated in the fat phobia that emerged once his misleading study was out.
Cristian Vlad Zot (Periodic Fasting: Repair your DNA, Grow Younger, and Learn to Appreciate your Food)
Ironically, the modern era of molecular biology, and all the extraordinary DNA technology that it entails, arguably began with a physicist, specifically with the publication of Erwin Schrödinger’s book What is Life? in 1944. Schrödinger made two key points: first, that life somehow resists the universal tendency to decay, the increase in entropy (disorder) that is stipulated by the second law of thermodynamics; and second, that the trick to life’s local evasion of entropy lies in the genes. He proposed that the genetic material is an ‘aperiodic’ crystal, which does not have a strictly repeating structure, hence could act as a ‘code-script’ – reputedly the first use of the term in the biological literature. Schrödinger himself assumed, along with most biologists at the time, that the quasicrystal in question must be a protein; but within a frenzied decade, Crick and Watson had inferred the crystal structure of DNA itself.
Nick Lane (The Vital Question: Why is life the way it is?)
Outsider music sometimes develops naturally. In other cases, it could be the product of damaged DNA, psychotic seizures, or alien abduction. Perhaps medical malpractice, incarceration, or simple drug-fry triggers its evolution. Maybe shrapnel in the head. Possession by the devil-or submission to Jesus. Chalk it up to communal upbringing or bad beer. There's no universal formula.
Irwin Chusid (Songs in the Key of Z: The Curious Universe of Outsider Music)
Eric R. Kandel, a Nobel Prize–winning neuropsychiatrist for his work on memory, shows how our thoughts, even our imaginations, get “under the skin” of our DNA and can turn certain genes on and certain genes off, changing the structure of the neurons in the brain.[1] So as we think and imagine, we change the structure and function of our brains. Even
Caroline Leaf (Switch On Your Brain: The Key to Peak Happiness, Thinking, and Health)
A team from Sydney, Australia, has lowered levels of these proteins using light. They implanted human genes associated with Alzheimer’s into mouse DNA, so that the animals developed abnormal tau proteins and amyloid plaques. Then they treated them for a month with low-level light therapy, simply by holding the light one to two centimeters above the animals’ heads. Using the same spectrum of near-infrared light that has helped in traumatic brain injury, Parkinson’s disease, and retinal damage, they lowered both the pathological tau proteins and the amyloid plaques by 70 percent in key brain areas that Alzheimer’s affects. Thereafter signs of “rusting” decreased, and the mitochondria, the powerhouses of the cells, improved their function.
Norman Doidge (The Brain's Way of Healing: Remarkable Discoveries and Recoveries from the Frontiers of Neuroplasticity)
In this model, there is a vicious cycle of events that results in the generation of a more and more repressed state. One of the predictions from this model is that repressive histone modifications attract DNA methyltransferases, which deposit DNA methylation near those histones. This methylation in turn attracts more repressive histone modifying enzymes, creating a self-perpetuating cycle that leads to an increasingly hostile region for gene expression. Experimental data suggest that in many cases this model seems to be right. Repressive histone modifications can act as the bait to attract DNA methylation to the promoter of a tumour suppressor gene. A key example of this is an epigenetic enzyme we met in the previous chapter, called EZH2. The EZH2 protein adds methyl groups to the lysine amino acid at position 27 on histone H3. This amino acid is known as H3K27. K is the single letter code for lysine (L is the code for a different amino acid called leucine).
Nessa Carey (The Epigenetics Revolution: How Modern Biology is Rewriting our Understanding of Genetics, Disease and Inheritance)
ncRNAs have recently been implicated in Lamarckian transmission of inherited characteristics. In one example, fertilised mouse eggs were injected with a miRNA which targeted a key gene involved in growth of heart tissue. The mice which developed from these eggs had enlarged hearts (cardiac hypertrophy) suggesting that the early injection of the miRNA disturbed the normal developmental processes. Remarkably, the offspring of these mice also had a high frequency of cardiac hypertrophy. This was apparently because the abnormal expression of the miRNA was recreated during generation of sperm in these mice. There was no change in the DNA code of the mice, so this was a clear case of a miRNA driving epigenetic inheritance
Nessa Carey (The Epigenetics Revolution: How Modern Biology is Rewriting our Understanding of Genetics, Disease and Inheritance)
All these experiments suggest two similar conclusions, which are the crux of this book: There is something “out there”: the matrix of an energy that connects any one thing with everything else in the universe. This connective field accounts for the unexpected results of the experiments. The DNA in our bodies gives us access to the energy that connects our universe, and emotion is the key to tapping in to the field.
Gregg Braden (The Divine Matrix: Bridging Time, Space, Miracles, and Belief)
At a quantum level, your environment is your attitude. What all of this means is that you can never be a victim of your DNA. Neither can you be a victim of fate. You can only be a victim of your attitude.
Richard Rudd (The Gene Keys: Embracing Your Higher Purpose)
imagine that your DNA is like a piano buried deep in your cells. The keys on the piano are your genes, which can be played in a variety of ways. Some keys will never be pressed. Others will be struck frequently and in steady combinations. Part of what distinguishes me from you and you from everyone else in the world is how these keys are pressed. That’s gene expression. It’s the genetic recital within your cells that plays a role in forming how your body and mind work. Our inner voice, it turns out, likes to tickle our genetic ivories. The way we talk to ourselves can influence which keys get played. The UCLA professor of medicine Steve Cole has spent his career studying how nature and nurture collide in our cells. Over the course of numerous studies he and his colleagues discovered that experiencing chatter-fueled chronic threat influences how our genes are expressed. When our internal conversations activate our threat system frequently over time, they send messages to our cells that trigger the expression of inflammation genes, which are meant to protect us in the short term but cause harm in the long term. At the same time, the cells carrying out normal daily functions, like warding off viral pathogens, are suppressed, opening the way for illnesses and infections. Cole calls this effect of chatter “death at the molecular level.
Ethan Kross
Once superintelligent AI has settled another solar system or galaxy, bringing humans there is easy — if humans have succeeded in programming the AI with this goal. All the necessary information about humans can be transmitted at the speed of light, after which the AI can assemble quarks and electrons into the desired humans. This could be done either in a low-tech way by simply transmitting the 2 gigabytes of information needed to specify a person’s DNA and then incubating a baby to be raised by the AI, or the AI could assemble quarks and electrons into full-grown people who would have all the memories scanned from their originals back on Earth. This means that if there’s an intelligence explosion, the key question isn’t if intergalactic settlement is possible, but simply how fast it can proceed. Since all the ideas we've explored above come from humans, they should be viewed as merely lower limits on how fast life can expand; ambitious superintelligent life can probably do a lot better, and it will have a strong incentive to push the limits, since in the race against time and dark energy, every 1% increase in average settlement speed translates into 3% more galaxies colonized. For example, if it takes 20 years to travel 10 light-years to the next star system with a laser-sail system, and then another 10 years to settle it and build new lasers and seed probes there, the settled region will be a sphere growing in all directions at a third of the speed of light on average. In a beautiful and thorough analysis of cosmically expanding civilizations in 2014, the American physicist Jay Olson considered a high-tech alternative to the island-hopping approach, involving two separate types of probes: seed probes and expanders. The seed probes would slow down, land and seed their destination with life. The expanders, on the other hand, would never stop: they'd scoop up matter in flight, perhaps using some improved variant of the ramjet technology, and use this matter both as fuel and as raw material out of which they'd build expanders and copies of themselves. This self-reproducing fleet of expanders would keep gently accelerating to always maintain a constant speed (say half the speed of light) relative to nearby galaxies, and reproduce often enough that the fleet formed an expanding spherical shell with a constant number of expanders per shell area. Last but not least, there’s the sneaky Hail Mary approach to expanding even faster than any of the above methods will permit: using Hans Moravec’s “cosmic spam” scam from chapter 4. By broadcasting a message that tricks naive freshly evolved civilizations into building a superintelligent machine that hijacks them, a civilization can expand essentially at the speed of light, the speed at which their seductive siren song spreads through the cosmos. Since this may be the only way for advanced civilizations to reach most of the galaxies within their future light cone and they have little incentive not to try it, we should be highly suspicious of any transmissions from extraterrestrials! In Carl Sagan’s book Contact, we earthlings used blueprints from aliens to build a machine we didn’t understand — I don’t recommend doing this ... In summary, most scientists and sci-fi authors considering cosmic settlement have in my opinion been overly pessimistic in ignoring the possibility of superintelligence: by limiting attention to human travelers, they've overestimated the difficulty of intergalactic travel, and by limiting attention to technology invented by humans, they've overestimated the time needed to approach the physical limits of what's possible.
Max Tegmark (Leben 3.0: Mensch sein im Zeitalter Künstlicher Intelligenz)
An interesting point: A cell in your brain and a cell in your kidney contain the exact same DNA. And while in utero (in the womb), the nascent (emerging, developing) cells differentiate into either a brain cell or a kidney cell only when crucial epigenetic processes turn the right genes on or off. So God has designed perfectly timed epigenetic signals to switch on in the womb as the baby is developing. “Before I formed you in the womb I knew you” (Jer. 1:5). Our
Caroline Leaf (Switch On Your Brain: The Key to Peak Happiness, Thinking, and Health)
Human Cloning: The Least Interesting Application of Cloning Technology One of the most powerful methods of applying life’s machinery involves harnessing biology’s own reproductive mechanisms in the form of cloning. Cloning will be a key technology—not for cloning actual humans but for life-extension purposes, in the form of “therapeutic cloning.” This process creates new tissues with “young” telomere-extended and DNA-corrected cells to replace without surgery defective tissues or organs. All responsible ethicists, including myself, consider human cloning at the present time to be unethical. The reasons, however, for me have little to do with the slippery-slope issues of manipulating human life. Rather, the technology today simply does not yet work reliably. The current technique of fusing a cell nucleus from a donor to an egg cell using an electric spark simply causes a high level of genetic errors.57 This is the primary reason that most of the fetuses created by this method do not make it to term. Even those that do make it have genetic defects. Dolly the Sheep developed an obesity problem in adulthood, and the majority of cloned animals produced thus far have had unpredictable health problems.58
Ray Kurzweil (The Singularity is Near: When Humans Transcend Biology)
Liberal politics is based on the idea that the voters know best, and there is no need for Big Brother to tell us what is good for us. Liberal economics is based on the idea that the customer is always right. Liberal art declares that beauty is in the eye of the beholder. Students in liberal schools and universities are taught to think for themselves. Commercials urge us to ‘Just do it.’ Action films, stage dramas, soap operas, novels and catchy pop songs indoctrinate us constantly: ‘Be true to yourself’, ‘Listen to yourself’, ‘Follow your heart’. Jean-Jacques Rousseau stated this view most classically: ‘What I feel to be good – is good. What I feel to be bad – is bad.’ People who have been raised from infancy on a diet of such slogans are prone to believe that happiness is a subjective feeling and that each individual best knows whether she is happy or miserable. Yet this view is unique to liberalism. Most religions and ideologies throughout history stated that there are objective yardsticks for goodness and beauty, and for how things ought to be. They were suspicious of the feelings and preferences of the ordinary person. At the entrance of the temple of Apollo at Delphi, pilgrims were greeted by the inscription: ‘Know thyself!’ The implication was that the average person is ignorant of his true self, and is therefore likely to be ignorant of true happiness. Freud would probably concur.fn1 And so would Christian theologians. St Paul and St Augustine knew perfectly well that if you asked people about it, most of them would prefer to have sex than pray to God. Does that prove that having sex is the key to happiness? Not according to Paul and Augustine. It proves only that humankind is sinful by nature, and that people are easily seduced by Satan. From a Christian viewpoint, the vast majority of people are in more or less the same situation as heroin addicts. Imagine that a psychologist embarks on a study of happiness among drug users. He polls them and finds that they declare, every single one of them, that they are only happy when they shoot up. Would the psychologist publish a paper declaring that heroin is the key to happiness? The idea that feelings are not to be trusted is not restricted to Christianity. At least when it comes to the value of feelings, even Darwin and Dawkins might find common ground with St Paul and St Augustine. According to the selfish gene theory, natural selection makes people, like other organisms, choose what is good for the reproduction of their genes, even if it is bad for them as individuals. Most males spend their lives toiling, worrying, competing and fighting, instead of enjoying peaceful bliss, because their DNA manipulates them for its own selfish aims. Like Satan, DNA uses fleeting pleasures to tempt people and place them in its power.
Yuval Noah Harari (Sapiens: A Brief History of Humankind)
Where carbon comes from in the universe is also a deep function of quantum physics. Like all the heavier elements, it us produced via nucleosynthesis (from nuclear fusion) in stars. But the high abundance of carbon (it comes in fourth in the count of atoms in today's universe, after hydrogen, helium, and oxygen) relies on several key properties of the cosmos. Most carbon forms through the triple-alpha process: the fusion of two helium nuclei into a beryllium-8 nucleus, followed by the fusion of the beryllium nucleus and another helium nucleus into carbon. This would be a horribly inefficient way to make carbon, except for some subtle coincidences. These coincidences are pretty technical, and may only be truly relished by nuclear physicists, but they're worth knowing about because they can help you grasp the connections between fundamental physics and us. The first coincidence is that in a star's interior, the combined energy of a beryllium-8 nucleus and a helium nucleus can closely match that of an energized carbon-12 atomic nucleus. This "resonance" in energies is key; it greatly enhances the rate of the next fusion step-making carbon-12. The second coincidence is that the nuclei of beryllium-8 just happen to be stable for long enough for them to have a good chance of catching one of those helium nuclei as they buzz around. And finally, the new carbon-12 nucleus is not efficient about immediately fusing with any spare helium nuclei to make a heavier oxygen nucleus-the carbon doesn't get gobbled up into oxygen, and lives to build your DNA a few billion years later.
Caleb Scharf (The Zoomable Universe: An Epic Tour Through Cosmic Scale, from Almost Everything to Nearly Nothing)
New York Times article from March 8, 1953, titled “Looking Back Two Billion Years.” “Obviously,” Edmond said, “this experiment raised some eyebrows. The implications could have been earth-shattering, especially for the religious world. If life magically appeared inside this test tube, we would know conclusively that the laws of chemistry alone are indeed enough to create life. We would no longer require a supernatural being to reach down from heaven and bestow upon us the spark of Creation. We would understand that life simply happens…as an inevitable by-product of the laws of nature. More importantly, we would have to conclude that because life spontaneously appeared here on earth, it almost certainly did the same thing elsewhere in the cosmos, meaning: man is not unique; man is not at the center of God’s universe; and man is not alone in the universe.” Edmond exhaled. “However, as many of you may know, the Miller-Urey experiment failed. It produced a few amino acids, but nothing even closely resembling life. The chemists tried repeatedly, using different combinations of ingredients, different heat patterns, but nothing worked. It seemed that life—as the faithful had long believed—required divine intervention. Miller and Urey eventually abandoned their experiments. The religious community breathed a sigh of relief, and the scientific community went back to the drawing board.” He paused, an amused glimmer in his eyes. “That is, until 2007…when there was an unexpected development.” Edmond now told the tale of how the forgotten Miller-Urey testing vials had been rediscovered in a closet at the University of California in San Diego after Miller’s death. Miller’s students had reanalyzed the samples using far more sensitive contemporary techniques—including liquid chromatography and mass spectrometry—and the results had been startling. Apparently, the original Miller-Urey experiment had produced many more amino acids and complex compounds than Miller had been able to measure at the time. The new analysis of the vials even identified several important nucleobases—the building blocks of RNA, and perhaps eventually…DNA. “It was an astounding science story,” Edmond concluded, “relegitimizing the notion that perhaps life does simply happen…without divine intervention. It seemed the Miller-Urey experiment had indeed been working, but just needed more time to gestate. Let’s remember one key point: life evolved over billions of years, and these test tubes had been sitting in a closet for just over fifty. If the timeline of this experiment were measured in miles, it was as if our perspective were limited to only the very first inch…” He let that thought hang in the air. “Needless to say,” Edmond went on, “there was a sudden resurgence in interest surrounding the idea of creating life in a lab.” I remember that, Langdon thought. The Harvard biology faculty had thrown
Dan Brown (Origin (Robert Langdon, #5))
Ten is formed from two pentagons and ten life-invoking pentagons sit perfectly arpund a decagon, and DNA, appropriately as the key to the reproduction of life, has ten steps for each turn of its double helix, so appears in cross-section as a tenfold rosette.
John Martineau (Quadrivium: The Four Classical Liberal Arts of Number, Geometry, Music, & Cosmology)
The key to Linus’ success was his reliance on the simple laws of structural chemistry. The α-helix had not been found by only staring at X-ray pictures; the essential trick, instead, was to ask which atoms like to sit next to each other. In place of pencil and paper, the main working tools were a set of molecular models superficially resembling the toys of preschool children
James D. Watson (The Double Helix: A Personal Account of the Discovery of the Structure of DNA)
A second key trait is to love and to connect the arts and sciences. Whenever Steve Jobs launched a new product such as the iPod or iPhone, his presentation ended with street signs that showed an intersection of Liberal Arts Street and Technology Street. “It’s in Apple’s DNA that technology alone is not enough,” he said at one of these presentations. “We believe that it’s technology married with the humanities that yields us the result that makes our heart sing.
Jeff Bezos (Invent and Wander: The Collected Writings of Jeff Bezos)
It is not only microbes that are benefiting from sharing our bodies, but us too. Our relationship with them is not just one of tolerance, but encouragement. This realisation, combined with the technical power of DNA sequencing and germ-free mouse studies, began a revolution in science. The Human Microbiome Project, run by the United States’ National Institutes for Health, alongside many other studies in laboratories around the world, has revealed that we utterly depend on our microbes for health and happiness.
Alanna Collen (10% Human: How Your Body’s Microbes Hold the Key to Health and Happiness)
This study showed that thinking and feeling anger, fear, and frustration caused DNA to change shape according to thoughts and feelings. The DNA responded by tightening up and becoming shorter, switching off many DNA codes, which reduced quality expression. So we feel shut down by negative emotions, and our body feels this too.
Caroline Leaf (Switch On Your Brain: The Key to Peak Happiness, Thinking, and Health)
Although the nucleus might have been recognized by Antonie van Leeuwenhoek in the late 17th century, it was not until 1831 that it was reported as a specific structure in orchid epidermal cells by a Scottish botanist, Robert Brown (better known for recognizing ‘Brownian movement’ of pollen grains in water). In 1879, Walther Flemming observed that the nucleus broke down into small fragments at cell division, followed by re-formation of the fragments called chromosomes to make new nuclei in the daughter cells. It was not until 1902 that Walter Sutton and Theodor Boveri independently linked chromosomes directly to mammalian inheritance. Thomas Morgan’s work with fruit flies (Drosophila) at the start of the 20th century showed specific characters positioned along the length of the chromosomes, followed by the realization by Oswald Avery in 1944 that the genetic material was DNA. Some nine years later, James Watson and Francis Crick showed the structure of DNA to be a double helix, for which they shared the Nobel Prize in 1962 with Maurice Wilkins, whose laboratory had provided the evidence that led to the discovery. Rosalind Franklin, whose X-ray diffraction images of DNA from the Wilkins lab had been the key to DNA structure, died of cancer aged 37 in 1958, and Nobel Prizes are not awarded posthumously. Watson and Crick published the classic double helix model in 1953. The final piece in the jigsaw of DNA structure was produced by Watson with the realization that the pairing of the nucleotide bases, adenine with thymine and guanine with cytosine, not only provided the rungs holding the twisting ladder of DNA together, but also provided a code for accurate replication and a template for protein assembly. Crick continued to study and elucidate the base pairing required for coding proteins, and this led to the fundamental ‘dogma’ that ‘DNA makes RNA and RNA makes protein’. The discovery of DNA structure marked an enormous advance in biology, probably the most significant since Darwin’s publication of On the Origin of Species .
Terence Allen (The Cell: A Very Short Introduction)
Breakthrough neuroscientific research is confirming daily what we instinctively knew all along: What you are thinking every moment of every day becomes a physical reality in your brain and body, which affects your optimal mental and physical health. These thoughts collectively form your attitude, which is your state of mind, and it’s your attitude and not your DNA that determines much of the quality of your life.
Caroline Leaf (Switch On Your Brain: The Key to Peak Happiness, Thinking, and Health)
The technically incorrect It’s me and That’s me have been part of our DNA since as long as English has been recorded. There’s something nice and low-key about them. Maybe we just crave a simple English equivalent of the French C’est moi.
Constance Hale (Sin and Syntax: How to Craft Wicked Good Prose)
The other theory argues that replication based on nucleic acids (RNA and/or DNA) came after biological entities could support metabolism. Günter Wächtershäuser proposed a version of this metabolism-first theory in which hot water from volcanoes flowed over mineral-rich rocks to ignite (catalyze) chemical reactions that fused simple carbon-based compounds into larger ones. While catalytic enzymes, which are proteins, did not yet exist, minerals, such as those in rocks, can and do function as prebiotic catalysts for chemical reactions. According to this theory, a key step occurred when, through a series of these prebiotic reactions, the circle was closed by the regeneration of the original compound. Through such a process, complex biological molecules (proteins, nucleotides, lipids, and carbohydrates) could be made, forming the basis of simple protocells that made energy and replicated.
Joseph E. LeDoux (The Deep History of Ourselves: The Four-Billion-Year Story of How We Got Conscious Brains)
One way to think about this is to imagine that your DNA is like a piano buried deep in your cells. The keys on the piano are your genes, which can be played in a variety of ways. Some keys will never be pressed. Others will be struck frequently and in steady combinations. Part of what distinguishes me from you and you from everyone else in the world is how these keys are pressed. That’s gene expression. It’s the genetic recital within your cells that plays a role in forming how your body and mind work.
Ethan Kross (Chatter: The Voice in Our Head, Why It Matters, and How to Harness It)
Through the magnetism of your living aura, you draw in or limit the frequencies of light deep into the cellular structure of your body. If you live your life out of fear, magnetically speaking you limit the amount of light that touches your DNA. The more open-hearted you are, the more you magnetise higher frequencies into that very same DNA. It is only at certain frequencies that particular codes can be activated.
Richard Rudd (The Gene Keys: Embracing Your Higher Purpose)
So when we make a poor-quality decision—when we choose to engage toxic thoughts (for example, unforgiveness, bitterness, irritation, or feelings of not coping)—we change the DNA and subsequent genetic expression, which then changes the shape of our brain wiring in a negative direction.
Caroline Leaf (Switch On Your Brain: The Key to Peak Happiness, Thinking, and Health)
Local and Nonlocal Effects of Coherent Heart Frequencies on Conformational Changes of DNA.” This study showed that thinking and feeling anger, fear, and frustration caused DNA to change shape according to thoughts and feelings. The DNA responded by tightening up and becoming shorter, switching off many DNA codes, which reduced quality expression. So we feel shut down by negative emotions, and our body feels this too. But here’s the great part: the negative shutdown or poor quality of the DNA codes was reversed by feelings of love, joy, appreciation, and gratitude!
Caroline Leaf (Switch On Your Brain: The Key to Peak Happiness, Thinking, and Health)
it is not uncommon for experts in DNA analysis to testify at a criminal trial that a DNA sample taken from a crime scene matches that taken from a suspect. How certain are such matches? When DNA evidence was first introduced, a number of experts testified that false positives are impossible in DNA testing. Today DNA experts regularly testify that the odds of a random person’s matching the crime sample are less than 1 in 1 million or 1 in 1 billion. With those odds one could hardly blame a juror for thinking, throw away the key. But there is another statistic that is often not presented to the jury, one having to do with the fact that labs make errors, for instance, in collecting or handling a sample, by accidentally mixing or swapping samples, or by misinterpreting or incorrectly reporting results. Each of these errors is rare but not nearly as rare as a random match. The Philadelphia City Crime Laboratory, for instance, admitted that it had swapped the reference sample of the defendant and the victim in a rape case, and a testing firm called Cellmark Diagnostics admitted a similar error.20 Unfortunately, the power of statistics relating to DNA presented in court is such that in Oklahoma a court sentenced a man named Timothy Durham to more than 3,100 years in prison even though eleven witnesses had placed him in another state at the time of the crime. It turned out that in the initial analysis the lab had failed to completely separate the DNA of the rapist and that of the victim in the fluid they tested, and the combination of the victim’s and the rapist’s DNA produced a positive result when compared with Durham’s. A later retest turned up the error, and Durham was released after spending nearly four years in prison.21 Estimates of the error rate due to human causes vary, but many experts put it at around 1 percent. However, since the error rate of many labs has never been measured, courts often do not allow testimony on this overall statistic. Even if courts did allow testimony regarding false positives, how would jurors assess it? Most jurors assume that given the two types of error—the 1 in 1 billion accidental match and the 1 in 100 lab-error match—the overall error rate must be somewhere in between, say 1 in 500 million, which is still for most jurors beyond a reasonable doubt. But employing the laws of probability, we find a much different answer. The way to think of it is this: Since both errors are very unlikely, we can ignore the possibility that there is both an accidental match and a lab error. Therefore, we seek the probability that one error or the other occurred. That is given by our sum rule: it is the probability of a lab error (1 in 100) + the probability of an accidental match (1 in 1 billion). Since the latter is 10 million times smaller than the former, to a very good approximation the chance of both errors is the same as the chance of the more probable error—that is, the chances are 1 in 100. Given both possible causes, therefore, we should ignore the fancy expert testimony about the odds of accidental matches and focus instead on the much higher laboratory error rate—the very data courts often do not allow attorneys to present! And so the oft-repeated claims of DNA infallibility are exaggerated.
Leonard Mlodinow (The Drunkard's Walk: How Randomness Rules Our Lives)
Flagyl was clearly effective in the treatment of Lyme disease. But how did it work? As early as 1967 The British Journal of Venereal Diseases had published a study showing Flagyl to be effective in certain cases of syphilis, and that it had an effect on bacterial DNA and RNA irrespective of bacterial replication. Could this be the mechanism of Flagyl’s action against Burrelia burgdorferi? The key to Flagyl’s effectiveness on Lyme, however, was not reported until several months after my study was presented. Dr. O. Brorson, a Norwegian researcher, published a paper on Flagyl and its effect on the cystic forms of Lyme disease six months after I presented my research. The cystic form of Lyme disease, it turns out, is one mechanism that Borrelia burgdorferi utilizes to persist in the body. Dr. Brorson reported that Flagyl would cause Borrelia cysts to rupture, and he went on to publish that he could see under the microscope the cell wall forms of Borrelia burgdorferi (helical/spiral–shaped organisms) transform into cystic forms, and under proper conditions convert back into mobile spirochetes. A review of the medical literature revealed that these cystic forms had, in fact, been reported in syphilis. No one had clearly made the link between Borrelia and a cystic form of the organism that could persist for long periods of time in a dormant state. It was a highly evolved survival mechanism that would allow the organism to reemerge when conditions were optimal. My patient, Mary, had been treated initially with Plaquenil, which according to Dr. Brorson’s research also affects the cystic forms, yet it appeared that it was not powerful enough to destroy the dormant forms and prevent a relapse, or to prevent her from passing it on to her fetus. She had also been treated with drugs that addressed the cell wall and intracellular forms of Lyme. Although Plaquenil has some effect on cystic forms, it is often primarily used in antibiotic regimens with Lyme disease to alkalize the intracellular compartment, modulate autoimmune reactions, and affect essential enzymes necessary for bacterial replication. Clearly, however, it is not powerful enough to destroy enough of the
Richard I. Horowitz (Why Can't I Get Better? Solving the Mystery of Lyme and Chronic Disease)
How did nature manage to evolve such complicated architecture? Mandelbrot's point is that the complications exist only in the context of traditional Euclidean geometry. As fractals, branching structures can be described with transparent simplicity, with just a few bits of information. Perhaps the simplest transformations that gave rise to the shapes devised by Koch, Peano, and Sierpinski have their analogue in the coded instructions of an organism's genes. DNA surely cannot specify the vast number of bronchi, bronchioles, and alveoli or the particular spatial structure of the resulting tree, but it can specify a repeating process of bifurcation and development. Such processes suit nature's purposes. When E.I. Dupont de Nemours & Company and the United States Army finally began to produce a synthetic match for goose down, it was by finally realizing that the phenomenal air-trapping ability of the natural product came from the fractal nodes and branches of down's key protein, keratin. Mandelbrot glided matter-of-factly from pulmonary and vascular trees to real botanical trees, trees that need to capture sun and resist wind, with fractal branches and fractal leaves. And theoretical biologists began to speculate that fractal scaling was not just common but universal in morphogenesis. They argued that understanding how such patterns were encoded and processed had become a major challenge to biology.
James Gleick (Chaos: Making a New Science)
At a quantum level, your environment is your attitude. What all of this means is that you can never be a victim of your DNA. Neither can you be a victim of fate. You can only be a victim of your attitude. Every thought you think, every feeling you have, every word you utter and every action you take directly programs your genes and therefore your reality. Consequently, at a quantum level, you create the environment that programs your genes.
Richard Rudd (The Gene Keys: Embracing Your Higher Purpose)
That the essential code for the 64 Gene Keys lies at the root of both our DNA and all computer programming is an indication of how profound and real these 64 codes of consciousness really are.
Richard Rudd (The Gene Keys: Embracing Your Higher Purpose)
Encrypted digital watermarking,” explains Balthazar. “Information gets hidden in information, like a code inside the pixels. Only visible with the right kind of key. It’s called steganography. Here,” pointing at the cylinder, “they’re using a similar technique, but done at the nano-level, with DNA as the information carrier. GFP is green fluorescent protein, in this case jellyfish genes woven into the atoms of the metal. The heat from your hand is the key.
Steven Kotler (Last Tango in Cyberspace)
What most people don’t realise is that as a salt, DNA is a natural conductor of electricity. It is extremely sensitive to electromagnetic waves. Even a slight shift in your mood will create enough of an environmental signal to trigger a response from your DNA. Likewise a negative or a positive thought will generate a subtle electromagnetic current throughout your body that will stir your DNA into some form of biological response. Most of us are completely unaware of how our moods, thoughts, beliefs and general attitude literally mould our bodies.
Richard Rudd (The Gene Keys: Embracing Your Higher Purpose)
The key finding was that the sequences of DNA generated implied that the human that led to us diverged from those who led to the Neanderthals around 500,000 years ago.
Adam Rutherford (A Brief History of Everyone Who Ever Lived: The Human Story Retold Through Our Genes)
Indigenous peoples' DNA is seen as a resource for use in medical, behavioral, anthropological, and genetic variation studies. Kanaka Maoli DNA has been sought for research at UH. For example, Dr. Charles Boyd, who was a researcher at UH's Pacific Biomedical Research Center, drafted a proposal for a Hawaiian Genome Project seeking $5–10 million to produce an annotated map of the entire genetic makeup of the Hawaiian people. Boyd stated, “There are many communities now with their own unique genetic history imprinted into their genomes and these include Asians, Europeans and the peoples of Oceania. The Hawaiian genome represents an important example of one of these communities of the Oceania people.”12 Boyd was hoping to target residents of the Hawaiian Homestead communities because they are seen as being the most purebred native Hawaiians. He hoped to find a genetic basis for the high rate of obesity, diabetes, renal disease, and hypertension in Kanaka Maoli.13 This type of research essentializes the role of genes, while devaluing key environmental and lifestyle factors, including the role dispossession of land has had in traditional diet and activities.
Noelani Goodyear-Ka‘ōpua (A Nation Rising: Hawaiian Movements for Life, Land, and Sovereignty (Narrating Native Histories))
But in the years that followed, science journalists the world over began expressing their disappointment in the contribution that knowledge of our complete DNA sequence had made to medicine. Although decoding our own instruction book is an irrefutable achievement that has made a difference to treatments for several important illnesses, it has not revealed as much as we expected about the causes of many common diseases. Searching for genetic differences in common to people with a particular disease did not throw up straightforward links for as many conditions as had been expected. Often, conditions were weakly linked to tens or hundreds of gene variants, but rarely was it the case that possessing a given gene variant would lead directly to a given disease.
Alanna Collen (10% Human: How Your Body's Microbes Hold the Key to Health and Happiness)
69. When You’re Going Through Hell, Keep Going Whether I have been in the middle of a dusty, barren desert, stuck in a mosquito-infested swamp, or freezing cold and wet in the middle of the ocean, there is always one thing I tell myself above everything else (and it is an easy one to remember, even when you are dog tired and not feeling particularly brave or strong). It’s this… …just keep going. JKG. Winston Churchill said it in one of the darkest moments of World War Two, when the outlook was as bleak as it had ever been. On 10 May 1940, the British looked to be finished. They stood alone against the vicious and victorious Nazis. Two weeks after Churchill came to power, France was knocked out of the war, and 340,000 British troops had to scramble to escape over the beaches at Dunkirk. The Germans had absolute control of all of Europe. It seemed impossible that Britain could survive. What was Churchill’s response? ‘When you’re going through hell, keep going.’ It is reassuring to know that the real heart of survival is as simple as this. All you have to do is to keep putting one foot in front of the other. Even if you don’t make much progress, you just have to keep going. It is not only the heart of survival, it is also the key to success. It’s really not that different when we face traumas elsewhere in our lives. Bereavement, illness and heartbreak are part of every human life. Sometimes the emotional impact of these events can bring us to our knees. But the way through is always the same: keep going. When we give up, we know our destiny. When we keep going, we earn the right to choose our fate. Ingrain it in your DNA: JKG.
Bear Grylls (A Survival Guide for Life: How to Achieve Your Goals, Thrive in Adversity, and Grow in Character)
No investigation of the human story in the Americas [...] can ignore the role of Siberia as a crossroads in the migrations of our ancestors. Moreover, despite the fact that only a tiny fraction of its vast area has yet been sampled by archaeologists, we already know that anatomically modern humans were present in both western and Arctic Siberia at least as far back as 45,000 years ago. We know, too, that DNA studies have revealed close genetic relationships between Native Americans and Siberians that speak to a deep and ancient connection.
Graham Hancock (America Before: The Key to Earth's Lost Civilization)
Because of the heightened sensitivity of your DNA, everything in your life, from the food you eat to the people you live with, is co-creating your body via your attitude. Your attitude determines the nature of the electromagnetic signals that reach your DNA.
Richard Rudd (The Gene Keys: Embracing Your Higher Purpose)