Diabetes Related Quotes

Since I’ve met you exactly five times so far, and during two of those you suffered from some diabetes-related complication that required my help.” “Eight more and I get a free sub?” He snorts a laugh. “With this level of self-sabotaging, you don’t need outside help.

Judging Natalie as my mother had judged me was, I felt like telling her son, just my ass-backward way of showing love. I'd spent my life trying to translate that language, and now I realized I had come to speak it fluently. When was it that you realized the thread woven through your DNA carried the relationship deformities of your blood relatives as much as it did their diabetes and bone density?

Associated with this weight gain are increased risks in adulthood for joint problems, angina, high blood pressure, heart attacks, strokes, type 2 diabetes and, ultimately, premature death. Outside of the human costs, health experts estimate that treating adult obesity-related ailments will cost the American economy nearly $150 billion in 2009.

It’s the combination of fat and a relatively high intake of carbohydrates—particularly refined ones—that can become a deadly recipe for obesity, diabetes, cardiovascular disease, and a host of other ills.

Stress can be bad for you. We no longer die of smallpox or the plague and instead die of stress-related diseases of lifestyle, like heart disease or diabetes, where damage slowly accumulates over time. It is understood how stress can cause or worsen disease or make you more vulnerable to other risk factors. Much of this is even understood on the molecular level. Stress can even cause your immune system to abnormally target hair follicles, causing your hair to turn gray.

The risks for heart disease, stroke, depression, diabetes, asthma, and even many cancers are all affected by trauma-related changes in the stress response system. Empathy and connection affect physical—not just mental—wellness and health.

Another, related issue is that longevity itself, and healthspan in particular, doesn’t really fit into the business model of our current healthcare system. There are few insurance reimbursement codes for most of the largely preventive interventions that I believe are necessary to extend lifespan and healthspan. Health insurance companies won’t pay a doctor very much to tell a patient to change the way he eats, or to monitor his blood glucose levels in order to help prevent him from developing type 2 diabetes. Yet insurance will pay for this same patient’s (very expensive) insulin after he has been diagnosed. Similarly, there’s no billing code for putting a patient on a comprehensive exercise program designed to maintain her muscle mass and sense of balance while building her resistance to injury. But if she falls and breaks her hip, then her surgery and physical therapy will be covered. Nearly all the money flows to treatment rather than prevention—and when I say “prevention,” I mean prevention of human suffering.

the odds are overwhelming that you will die as a result of one of the chronic diseases of aging that I call the Four Horsemen: heart disease, cancer, neurodegenerative disease, or type 2 diabetes and related metabolic dysfunction. To achieve longevity—to live longer and live better for longer—we must understand and confront these causes of slow death.

I should also add something about weight here, because we all know that there’s often a relationship between weight and risk for diabetes. If the risk for Alzheimer’s disease goes up with metabolic disorders, then it makes sense that the risk also rises with unhealthy weight gain that has metabolic consequences. The science now speaks to this fact. Carrying extra weight around the abdomen has been shown to be particularly harmful to the brain. One study that garnered lots of media attention looked at over six thousand individuals aged forty to forty-five and measured the size of their bellies between 1964 and 1973.11 A few decades later, they were evaluated to see who had developed dementia and how that related to their waist size at the start of the study. The correlation between risk of dementia and thicker midsections twenty-seven years earlier was remarkable: Those with the highest level of abdominal fat had an increased risk of dementia of almost three-fold in comparison to those with the lowest abdominal weight. There is plenty of evidence that managing your weight now will go a long way toward preventing brain decline later.

The mummified remains of Queen Nefertiti suggest that she most likely had diabetes. The legendary queen was not the only one with problems related to her grain-heavy diet. In fact, oatmeal has been associated with dental problems even in modern times.

Your waist size is such an important predictor of health because the type of fat that is stored around your waistline—called “visceral fat” or “belly fat”—is related to the release of proteins and hormones that cause inflammation, which can in turn damage your arteries and affect how you metabolize sugars and fats. For this reason, visceral fat is strongly linked to type 2 diabetes, heart disease, stroke, Alzheimer’s, and other chronic diseases. Seeing your waist size come down is a great indicator of improving health.

There is no such thing as protein deficiency in the United States. How many people do you know who were hospitalized last year for protein deficiency? Zero! Now, how many people do you know who were hospitalized for heart disease, cancer, diabetes, or obesity related ailments? Probably lots

Calorie restriction extends the life span of every organism so far tested, including yeast, worms, flies, rodents, and monkeys. It also slows or even prevents age-related diseases, including dementia, diabetes, cardiovascular and coronary disease, neurodegenerative disorders, and several types of cancer.

overwhelming that you will die as a result of one of the chronic diseases of aging that I call the Four Horsemen: heart disease, cancer, neurodegenerative disease, or type 2 diabetes and related metabolic dysfunction. To achieve longevity—to live longer and live better for longer—we must understand and confront these causes of slow death.

Virtually every person who uses the WFPB diet loses weight, reduces their blood sugar and insulin levels, and resolves diabetes and related diseases. A plant protein–based diet (as in the high-carb WFPB diet) also decreases total blood cholesterol and the formation of plaques that lead to heart disease, effects not seen from a low-carb, animal protein–based diet.

Homelessness was fed by racism, income inequality, and a cascade of other related forces. These included insufficient investments in public housing, as well as tax and zoning codes that had spurred widespread gentrification and driven up rents. Many poor and moderately poor Americans lived with the fear of losing housing, which can itself harm bodies and minds as well as social relations in families. One recent study had found that “unstable housing” was accompanied by a twofold increase in diabetic emergencies. Illnesses such as diabetes, and all sorts of accidents and injuries, could lead to homelessness, which itself bred other illnesses, such as PTSD—redefined by one practitioner of street medicine as “persistent traumatic stress disorder.

Nobody is ever made happy by winning the lottery, buying a house, getting a promotion or even finding true love. People are made happy by one thing and one thing only – pleasant sensations in their bodies. A person who just won the lottery or found new love and jumps from joy is not really reacting to the money or the lover. She is reacting to various hormones coursing through her bloodstream and to the storm of electric signals flashing between different parts of her brain. Unfortunately for all hopes of creating heaven on earth, our internal biochemical system seems to be programmed to keep happiness levels relatively constant. There's no natural selection for happiness as such - a happy hermit's genetic line will go extinct as the genes of a pair of anxious parents get carried on to the next generation. Happiness and misery play a role in evolution only to the extent that they encourage or discourage survival and reproduction. Perhaps it's not surprising, then, that evolution has moulded us to be neither too miserable nor too happy. It enables us to enjoy a momentary rush of pleasant sensations, but these never last for ever. Sooner of later they subside and give place to unpleasant sensations. (...) Some scholars compare human biochemistry to an air-conditioning system that keeps the temperature constant, come heatwave or snowstorm. Events might momentarily change the temperature, but the air-conditioning system always returns the temperature to the same set point. Some air-conditioning systems are set at twenty-five degrees Celsius. Others are set at twenty degrees. Human happiness conditioning systems also differ from person to person. On a scale from one to ten, some people are born with a cheerful biochemical system that allows their mood to swing between levels six and ten, stabilising with time at eight. Such a person is quite happy even if she lives in an alienating big city, loses all her money in a stock-exchange crash and is diagnosed with diabetes. Other people are cursed with a gloomy biochemistry that swings between three and seven and stabilises at five. Such an unhappy person remains depressed even if she enjoys the support of a tight-knit community, wins millions in the lottery and is as healthy as an Olympic athlete (...) incapable of experiencing anything beyond level seven happiness. Her brain is simply not built for exhilaration, come what may. (...) Buying cars and writing novels do not change our biochemistry. They can startle it for a fleeting moment, but it is soon back to the set point.

Both vitamin pills and vegetables are loaded with essential nutrients, but not in the same combinations. Spinach is a good source of both vitamin C and iron. As it happens, vitamin C boosts iron absorption, allowing the body to take in more of it than if the mineral were introduced alone. When I first started studying nutrition, I became fascinated with these coincidences, realizing of course they're not coincidences. Human bodies and their complex digestive chemistry evolved over millenia in response to all the different foods--mostly plants--they raised or gathered from the land surrounding them. They may have died young from snakebite or blunt trauma, but they did not have diet-related illnesses like heart disease and Type II diabetes that are prevalent in our society now, even in some young adults and children. [from an entry by Barbara Kingsolver's daughter Camille]

Human evolution is not over, but the chances of natural selection adapting our species in dramatic, major ways to common non-infectious mismatch diseases are remote unless conditions change dramatically. One reason is that many of these diseases have little to no effect on fertility. Type 2 diabetes, for example, generally develops after people have reproduced, and even then, it is highly manageable for many years.8 Another consideration is that natural selection can act only on variations that affect reproductive success and that are also genetically passed from parent to offspring. Some obesity-related illnesses can hinder reproductive function, but these problems have strong environmental causes.9 Finally, although culture sometimes spurs selection, it is also a powerful buffer. Every year new products and therapies are being developed that allow people with common mismatch diseases to cope better with their symptoms. Whatever selection is operating is probably occurring at a pace too slow to measure in our lifetimes.

HUNGER AND OBESITY The change in diets around the world is also creating a global obesity epidemic—and in its wake a global diabetes epidemic—even as more than 900 million people in the world still suffer from chronic hunger. In the United States, where many global trends begin, the weight of the average American has increased by approximately twenty pounds in the last forty years. A recent study projects that half the adult population of the United States will be obese by 2030, with one quarter of them “severely obese.” At a time when hunger and malnutrition are continuing at still grossly unacceptable levels in poor countries around the world (and in some pockets within developed countries), few have missed the irony that simultaneously obesity is at record levels in developed countries and growing in many developing countries. How could this be? Well, first of all, it is encouraging to note that the world community has been slowly but steadily decreasing the number of people suffering from chronic hunger. Secondly, on a global basis, obesity has more than doubled in the last thirty years. According to the World Health Organization, almost 1.5 billion adults above the age of twenty are overweight, and more than a third of them are classified as obese. Two thirds of the world’s population now live in countries where more people die from conditions related to being obese and overweight than from conditions related to being underweight. Obesity represents a major risk factor for the world’s leading cause of death—cardiovascular diseases, principally heart disease and stroke—and is the major risk factor for diabetes, which has now become the first global pandemic involving a noncommunicable disease.* Adults with diabetes are two to four times more likely to suffer heart disease or a stroke, and approximately two thirds of those suffering from diabetes die from either stroke or heart disease.† The tragic increase in obesity among children is particularly troubling; almost 17 percent of U.S. children are obese today, as are almost 7 percent of all children in the world. One respected study indicates that 77 percent of obese children will suffer from obesity as adults. If there is any good news in the latest statistics, it is that the prevalence of obesity in the U.S. appears to be reaching a plateau, though the increases in childhood obesity ensure that the epidemic will continue to grow in the future, both in the U.S. and globally. The causes of this surge in obesity are both simple—in that people are eating too much and exercising

Genes can be activated or turned off by factors in the environment. In the Cree population of northwestern Ontario, for example, diabetes is found at a rate five times the Canadian national average, despite the traditionally low incidence of diabetes among native peoples. The genetic makeup of the Cree people cannot have changed in a few generations. The destruction of the Crees’ traditional physically active ways of life, the substitution of high-calorie diets for their previous low-fat, low-carbohydrate eating patterns and greatly increased stress levels are responsible for the alarming rise in diabetes rates. Although heredity is involved in diabetes, it cannot possibly account for the pandemic among Canada’s native peoples, or among the rest of the North American population, for that matter. We will see that in similar ways changes in society are causing more and more children to be affected by attention deficit disorder. It is easy to jump to hasty conclusions about genetic information. Some studies have identified certain genes, for example, that are said to be more common among people with attention deficit disorder or with other related conditions, such as depression, alcoholism or addiction. But even if the existence of these genes is proven, there is no reason to suppose that they can, on their own, induce the development of ADD or any other disorder. First, not everyone with these genes will have the disorders. Second, not everyone with the disorders will be shown to carry the genes.

Just as calories differ according to how they affect the body, so too do carbohydrates. All carbohydrates break down into sugar, but the rate at which this occurs in the digestive tract varies tremendously from food to food. This difference forms the basis for the glycemic index (GI). The GI ranks carbohydrate-containing foods according to how they affect blood glucose, from 0 (no affect at all) to 100 (equal to glucose). Gram for gram, most starchy foods raise blood glucose to very high levels and therefore have high GI values. In fact, highly processed grain products – like white bread, white rice, and prepared breakfast cereals – and the modern white potato digest so quickly that their GI ratings are even greater than table sugar (sucrose). So for breakfast, you could have a bowl of cornflakes with no added sugar, or a bowl of sugar with no added cornflakes. They would taste different but, below the neck, act more or less the same. A related concept is the glycemic load (GL), which accounts for the different carbohydrate content of foods typically consumed. Watermelon has a high GI, but relatively little carbohydrate in a standard serving, producing a moderate GL. In contrast, white potato has a high GI and lots of carbohydrate in a serving, producing a high GL. If this sounds a bit complicated, think of GI as describing how foods rank in a laboratory setting, whereas GL as applying more directly to a real-life setting. Research has shown that the GL reliably predicts, to within about 90 percent, how blood glucose will change after an actual meal – much better than simply counting carbohydrates as people with diabetes have been taught to do.

And, even more important for our purposes, these facts are sturdy enough that we can build a sensible diet upon them. Here they are: FACT 1. Populations that eat a so-called Western diet—generally defined as a diet consisting of lots of processed foods and meat, lots of added fat and sugar, lots of refined grains, lots of everything except vegetables, fruits, and whole grains—invariably suffer from high rates of the so-called Western diseases: obesity, type 2 diabetes, cardiovascular disease, and cancer. Virtually all of the obesity and type 2 diabetes, 80 percent of the cardiovascular disease, and more than a third of all cancers can be linked to this diet. Four of the top ten killers in America are chronic diseases linked to this diet. The arguments in nutritional science are not about this well-established link; rather, they are all about identifying the culprit nutrient in the Western diet that might be responsible for chronic diseases. Is it the saturated fat or the refined carbohydrates or the lack of fiber or the transfats or omega-6 fatty acids—or what? The point is that, as eaters (if not as scientists), we know all we need to know to act: This diet, for whatever reason, is the problem. FACT 2. Populations eating a remarkably wide range of traditional diets generally don’t suffer from these chronic diseases. These diets run the gamut from ones very high in fat (the Inuit in Greenland subsist largely on seal blubber) to ones high in carbohydrate (Central American Indians subsist largely on maize and beans) to ones very high in protein (Masai tribesmen in Africa subsist chiefly on cattle blood, meat, and milk), to cite three rather extreme examples. But much the same holds true for more mixed traditional diets. What this suggests is that there is no single ideal human diet but that the human omnivore is exquisitely adapted to a wide range of different foods and a variety of different diets. Except, that is, for one: the relatively new (in evolutionary terms) Western diet that most of us now are eating. What an extraordinary achievement for a civilization: to have developed the one diet that reliably makes its people sick! (While it is true that we generally live longer than people used to, or than people in some traditional cultures do, most of our added years owe to gains in infant mortality and child health, not diet.) There is actually a third, very hopeful fact that flows from these two: People who get off the Western diet see dramatic improvements in their health. We have good research to suggest that the effects of the Western diet can be rolled back, and relatively quickly.

There is no such thing as protein deficiency in the United States. How many people do you know who were hospitalized last year for protein deficiency? Zero! Now, how many people do you know who were hospitalized for heart disease, cancer, diabetes, or obesity-related ailments? Probably lots.

Now, I know that people with diabetes have heard over and over that they must limit rice, pasta, and other starchy foods. But keep in mind that diabetes—and overweight—has been rare in countries that have made these foods their staples. The plan does have rules about carbohydrates, but they relate mainly to which ones you choose, not how much. In our studies, we have found that people who include plenty of healthy carbohydrates in their diets do better, not worse.

Normally, when sugar enters the bloodstream from our gut, the pancreas secretes insulin into the bloodstream, and the insulin then travels to three main places: fat cells, muscle cells, and neurons. Insulin’s primary job is to open the door to any cell to allow glucose to enter and provide fuel, particularly to three important types of cells. 1. IN FAT CELLS, insulin attaches to a docking port on a fat cell membrane and flips a switch that tells the fat cell to convert that glucose to fat and store it. When insulin has done its job, it separates from the docking port and no more sugar can enter the cell. 2. IN MUSCLE CELLS, insulin unlocks the door to the cell and ushers in glucose to be used as fuel. 3. NERVE CELLS (neurons) also require insulin to admit glucose through their cell membrane. The fact that neurons require insulin to get glucose is a relatively new finding, and we now know that insulin resistance also occurs in the brain and nerves—it is called type 3 diabetes. Once insulin docks in the appropriate ports and releases information, the fat, muscle, or nerve cells tell the hormone that the message has been received. The hormone then backs out of the docking port, leaving it ready and available for the next hormone to attach.

One way to quantify the extension of morbidity currently occurring is a metric known as disability-adjusted life years (DALYs), which measures a disease’s overall burden as the number of years lost to ill health plus death.65 According to an impressive recent analysis of medical data worldwide from between 1990 and 2010, the burden of disability caused by communicable and nutrition-related diseases has plunged by more than 40 percent, while the burden of disability caused by noncommunicable diseases has risen, especially in developed nations. As examples, DALYs have risen by 30 percent for type 2 diabetes, by 17 percent for neurological disorders, such as Alzheimer’s, by 17 percent for chronic kidney disease, by 12 percent for musculoskeletal disorders, such as arthritis and back pain, by 5 percent for breast cancer, and by 12 percent for liver cancer.66 Even after factoring in population growth, more people are experiencing more chronic disability that results from noncommunicable diseases. For the diseases just mentioned, the number of years a person can expect to live with cancer has increased by 36 percent, with heart and circulatory diseases by 18 percent, with neurological diseases by 12 percent, with diabetes by 13 percent, and with musculoskeletal diseases by 11 percent.67 To many, old age is now equated with various disabilities (and

LESSONS FROM A WHEAT-FREE EXPERIMENT An interesting fact: Whole wheat bread (glycemic index 72) increases blood sugar as much as or more than table sugar, or sucrose (glycemic index 59). (Glucose increases blood sugar to 100, hence a glycemic index of 100. The extent to which a particular food increases blood sugar relative to glucose determines that food’s glycemic index.) So when I was devising a strategy to help my overweight, diabetes-prone patients reduce blood sugar most efficiently, it made sense to me that the quickest and simplest way to get results would be to eliminate the foods that caused their blood sugar to rise most profoundly: in other words, not sugar, but wheat.

A study of diabetes (a lifestyle-related epidemic in our nation) published in the Journal of Internal Medicine showed that lifestyle-change programs achieved the same beneficial result as drug treatment at a cost of $8,800 versus $29,900—a 70 percent reduction. How often do you get something for 70 percent off?

High unmitigated communion is associated with poor adjustment, both physically and psychologically, and is linked to heart disease, diabetes, and cancer, perhaps because the focus on others keeps those high on the scale from attending to themselves. Helgeson and Fritz speculate that the gender difference here explains women’s greater propensity to anxiety and depression, a conclusion that meshes with the proposal by Barbara Oakley, who, drawing on work on “pathological altruism,” notes, “It’s surprising how many diseases and syndromes commonly seen in women seem to be related to women’s generally stronger empathy for and focus on others.

the Horsemen: cardiovascular and cerebrovascular disease, cancer, Alzheimer’s disease and related neurodegenerative conditions, and type 2 diabetes and related metabolic dysfunction.

Another, related issue is that longevity itself, and healthspan in particular, doesn’t really fit into the business model of our current healthcare system. There are few insurance reimbursement codes for most of the largely preventive interventions that I believe are necessary to extend lifespan and healthspan. Health insurance companies won’t pay a doctor very much to tell a patient to change the way he eats, or to monitor his blood glucose levels in order to help prevent him from developing type 2 diabetes. Yet insurance will pay for this same patient’s (very expensive) insulin after he has been diagnosed.

you’re diabetic, you never want your insulin levels to get too low—cells are deprived of energy, circulating glucose levels get too high. But you don’t want to take too much insulin. For complex reasons, this deprives the brain of energy, potentially putting you into shock or a coma and damaging neurons.

How does chronic stress affect this process? First, the hormones of the stress-response cause even more glucose and fatty acids to be mobilized into the bloodstream. For a juvenile diabetic, this increases the likelihood of the now-familiar pathologies of glucose and fatty acids gumming up in the wrong places.

In adult-onset diabetes (type 2, non-insulin-dependent diabetes), the trouble is not too little insulin, but the failure of the cells to respond to insulin. Another name for the disorder is thus insulin-resistant diabetes.

Migraine, like my patient Sarah had, also correlates closely to poor metabolic health. In the ENT otology clinic, we often saw this condition and had limited success in treating it. Sufferers of this debilitating neurological disease—about 12 percent of people in the United States—tend to have higher insulin levels and insulin resistance. A comprehensive review of fifty-six research articles identified links between migraine and poor metabolic health, pointing out that “migraine sufferers tend to have impaired insulin sensitivity.” The review supports the “neuro-energetic” theory of migraine. Additionally, evidence suggests that micronutrient deficiencies in key mitochondrial cofactors may also be a contributing factor of migraine. Research has suggested that migraines could be treated by restoring levels of vitamins B and D, magnesium, CoQ10, alpha lipoic acid, and L-carnitine. Vitamin B12, for instance, is involved in the electron transport chain responsible for the final steps of ATP generation in the mitochondria, and studies have indicated that high doses of B12 can help prevent migraine. These micronutrients usually have fewer side effects than other drugs used to treat migraines, making them a promising option for relief, which can be obtained through a diet rich in these micronutrients, or supplementation. Having high markers of oxidative stress, a key Bad Energy feature, is associated with a significantly higher risk of migraine in women, with some studies suggesting that migraine attacks are a symptomatic response to increased levels of oxidative stress. Less painful and more common tension-type headaches are also linked to high variability (excess peaks and crashes) in blood sugar. Hearing Loss The same story of metabolic ignorance in the ENT department unfolded for auditory problems and hearing loss, one of the most common issues presented to our ENT clinic. We’d typically tell our patients that their auditory decline was inevitable, due to aging and loud concerts in their youth, and we would suggest interventions like hearing aids. Yet insulin resistance is a little-known link to hearing problems. If you have insulin resistance, you are more likely to lose hearing as you age because of poor energy production in the delicate hearing cells and blockage of the small blood vessels that supply the inner ear. One study showed that insulin resistance is associated with age-related hearing loss, even when controlling for weight and age. The likely mechanism for this is that the auditory system requires high energy utilization for its complex signal processing. In the case of insulin resistance, glucose metabolism is disturbed, leading to decreased energy generation. The impact of Bad Energy on hearing is not subtle: A study showed that the prevalence of high-frequency hearing impairment among subjects with elevated fasting glucose levels was 42 percent compared to 24 percent in those with normal fasting glucose. Moreover, insulin resistance is associated with high-frequency mild hearing impairment in the male population under seventy years of age, even before the onset of diabetes. These papers suggest that assessing early metabolic function and levels of insulin resistance is essential in the ENT clinic and counseling individuals on the potential warning signs is paramount.

Diabetes – the physical costs Hypertension: 70% of diabetics also require medication for blood pressure. Cholesterol: 65% of diabetics require medication to reduce their cholesterol. Heart attacks: Diabetics, even when on full medication, are twice as likely to be hospitalised, crippled or die from a heart attack. Strokes: Diabetics are 1.5 times more likely to suffer a debilitating stroke. Blindness and Eye Problems: Diabetes is the number one cause of preventable blindness in the developed world. Impotence: Diabetes is also the number one cause of impotence. Dementia: Having diabetes doubles your risk of dementia. Kidney disease: Diabetes is the cause of kidney failure in half of all new cases; most people on dialysis are diabetics. Amputations: There are over 7000 diabetes-related amputations done every year in the UK and over 73,000 in the US.

In 2012, the U.S. Food and Drug Administration announced newly mandated safety labeling on statin drugs to warn doctors and patients about their potential for brain-related side effects, such as memory loss and confusion. Statin drugs also appeared to increase the risk of developing diabetes.37 In 2013, a study of several thousand breast cancer patients reported that long-term use of statins may as much as double a woman’s risk of invasive breast cancer.

Those with cardiovascular disease not identified with diabetes are simply undiagnosed. Dr. Stout in 1977 identified the origin of the pathology of type 2 diabetes as vascular (arterial), directly related to hyperinsulinemia and not to hypergly-cemia.

If you’re like most people, a string of nerve-racking incidents keeps you in fight-or-flight response—and out of homeostasis—a large part of the time. Maybe the car cutting you off is the only actual life-threatening situation you encounter all day, but the traffic on the way to work, the pressure of preparing for a big presentation, the argument you had with your spouse, the credit-card bill that came in the mail, the crashing of your computer hard drive, and the new gray hair you noticed in the mirror keep the stress hormones circulating in your body on a near-constant basis. Between remembering stressful experiences from the past and anticipating stressful situations coming up in your future, all these repetitive short-term stresses blur together into long-term stress. Welcome to the 21st-century version of living in survival mode. In fight-or-flight mode, life-sustaining energy is mobilized so that the body can either run or fight. But when there isn’t a return to homeostasis (because you keep perceiving a threat), vital energy is lost in the system. You have less energy in your internal environment for cell growth and repair, long-term building projects on a cellular level, and healing when that energy is being channeled elsewhere. The cells shut down, they no longer communicate with one another, and they become “selfish.” It’s not time for routine maintenance (let alone for making improvements); it’s time for defense. It’s every cell for itself, so the collective community of cells working together becomes fractured. The immune and endocrine systems (among others) become weakened as genes in those related cells are compromised when informational signals from outside the cells are turned off. It’s like living in a country where 98 percent of the resources go toward defense, and nothing is left for schools, libraries, road building and repair, communication systems, growing of food, and so on. Roads develop potholes that aren’t fixed. Schools suffer budget cuts, so students wind up learning less. Social welfare programs that took care of the poor and the elderly have to close down. And there’s not enough food to feed the masses. Not surprisingly, then, long-term stress has been linked to anxiety, depression, digestive problems, memory loss, insomnia, hypertension, heart disease, strokes, cancer, ulcers, rheumatoid arthritis, colds, flu, aging acceleration, allergies, body pain, chronic fatigue, infertility, impotence, asthma, hormonal issues, skin rashes, hair loss, muscle spasms, and diabetes, to name just a few conditions (all of which, by the way, are the result of epigenetic changes). No organism in nature is designed to withstand the effects of long-term stress.

A Family Affair: Essential Fatty Acids More chemical clues to the nature of alcoholism come from research focusing on alcoholics with at least one grandparent who was Welsh, Irish, Scottish, Scandinavian, or native American. Typically, these alcoholics have a history of depression going back to childhood and close relatives who suffered from depression or schizophrenia. Some may have relatives who committed suicide. There also may be a family history of eczema, cystic fibrosis, premenstrual syndrome, diabetes, irritable bowel syndrome, or benign breast disease. The common denominator here is a genetic abnormality in the way the body handles certain essential fatty acids (EFAs) derived from foods. Normally, these EFAs are converted in the brain to various metabolites such as prostaglandin E1 (PGE1), which plays a vital role in the prevention of depression, convulsions, and hyperexcitability. When the EFA conversion process is defective, brain levels of prostaglandin E1 are lower than normal, which results in depression. In affected individuals, alcohol acts as a double-edged sword. It activates the PGE1 within the brain, which immediately lifts depression and creates feelings of well-being. Because the brain cannot make new PGE1 efficiently, its meager supply of PGE1 is gradually depleted. Over time, the ability of alcohol to lift depression slowly diminishes. Several years ago, researchers hit upon a solution to this problem. They discovered that a natural substance, oil of evening primrose, contains large amounts of gamma-linolenic acid (GLA), which can help the brain convert EFAs to PGE1. The results are quite dramatic. In a recent study in Scotland, researcher David Horrobin, M.D., matched two groups of alcoholics whose EFA levels were 50 percent below normal. The first group got EFA replacement, the second, a placebo. Marked differences between the two groups emerged in the withdrawal stage. The group that got EFA replacement had far fewer symptoms, while the placebo group displayed the full range of withdrawal symptoms associated with prostaglandin deficiency: tremors, irritability, tension, hyperexcitability, and convulsions. At the outset of the study, members of both groups had some degree of alcohol-related liver damage. Three months later, the researchers found that liver function among the EFA replacement group was almost normal. There was no significant improvement among the placebo group. A year later, the placebo group was still deficient in the natural ability to convert essential fatty acids into PGE1. What’s more, only 28 percent of this group had remained sober; the rest had resumed drinking. Results were dramatically better among the EFA replacement group: 83 percent remained sober and depression free.

Excessive chemicals eventually inhibit your immune system (the defence against infections and illnesses) making you vulnerable to viruses of every shape and size. They will lower the production of serotonin (making you feel listless and joyless as in depression) and can eventually, if they remain virulent, cause heart disease, hardening of the arteries, type 2 diabetes and certain cancers. Inadvertently stress will destroy you both mentally and physically unless you change the way you think about it and relate to it. With

Reduced Disease Risk Factors: Ditching grains, sugars, other simple carbs, and processed foods, especially “bad fats” (trans and partially-hydrogenated), will reduce your production of hormone-like messengers that instruct genes to make harmful pro-inflammatory protein agents. These agents increase your risk for arthritis, diabetes, cancer, heart disease, and many other inflammation-related health problems.

state of calm produced by meditation, yoga, and breathing exercises—actually switched on genes that are related to augmenting our immune system, reducing inflammation, and fighting a range of conditions from arthritis to high blood pressure to diabetes. So with all these results, it’s no surprise that, according to another study, meditation correlates to reduced yearly medical costs. It

What causes insulin resistance? Typically, it is a combination of genetics (heredity) and lifestyle (the way we live). Having blood relatives (parents, siblings) with type 2 diabetes greatly increases the risk. Certain ethnic groups, including Native Americans and people of African, Hispanic, Asian, and Pacific Island descent, are also at high risk. The aging process plays a role as well. The older we get, the more insulin resistant we tend to become.

China is perhaps the best-studied example. There, a transition away from the country’s traditional, plant-based diet was accompanied by a sharp rise in diet-related chronic diseases, such as obesity, diabetes, cardiovascular diseases, and cancer.38

Many years later, research by Keiko Hayashi, Ph.D., of the University of Tsukuba in Japan showed the same thing. 12 In Hayashi’s study, diabetic patients watching an hour-long comedy program upregulated a total of 39 genes, 14 of which were related to natural killer cell activity. While none of these genes were directly involved in blood-glucose regulation, the patients’ blood-glucose levels were better controlled than after they listened to a diabetes health lecture on a different day. Researchers surmised that laughter influences many genes involved with immune response, which in turn contributed to the improved glucose control. The elevated emotion, triggered by the patients’ brains, turned on the genetic variations, which activated the natural killer cells and also somehow improved their glucose response—probably in addition to many other beneficial effects. As Cousins said of placebos back in 1979, “The process works not because of any magic in the tablet, but because the human body is its own best apothecary and because the most successful prescriptions are filled by the body itself.

The coast of Austria-Hungary yielded what people called cappuzzo, a leafy cabbage. It was a two-thousand-year-old grandparent of modern broccoli and cauliflower, that was neither charismatic nor particularly delicious. But something about it called to Fairchild. The people of Austria-Hungary ate it with enthusiasm, and not because it was good, but because it was there. While the villagers called it cappuzzo, the rest of the world would call it kale. And among its greatest attributes would be how simple it is to grow, sprouting in just its second season of life, and with such dense and bulky leaves that in the biggest challenge of farming it seemed to be how to make it stop growing. "The ease with which it is grown and its apparent favor among the common people this plant is worthy a trial in the Southern States," Fairchild jotted. It was prophetic, perhaps, considering his suggestion became reality. Kale's first stint of popularity came around the turn of the century, thanks to its horticultural hack: it drew salt into its body, preventing the mineralization of soil. Its next break came from its ornamental elegance---bunches of white, purple, or pink leaves that would enliven a drab garden. And then for decades, kale kept a low profile, its biggest consumers restaurants and caterers who used the cheap, bushy leaves to decorate their salad bars. Kale's final stroke of luck came sometime in the 1990s when chemists discovered it had more iron than beef, and more calcium, iron, and vitamin K than almost anything else that sprouts from soil. That was enough for it to enter the big leagues of nutrition, which invited public relations campaigns, celebrity endorsements, and morning-show cooking segments. American chefs experimented with the leaves in stews and soups, and when baked, as a substitute for potato chips. Eventually, medical researchers began to use it to counter words like "obesity," "diabetes," and "cancer." One imagines kale, a lifetime spent unnoticed, waking up one day to find itself captain of the football team.

Supplements may hinder autophagy. When fasting for metabolic reasons (meaning insulin resistance–related conditions such as type 2 diabetes, obesity, PCOS, and nonalcoholic fatty liver disease), the effectiveness of supplements is questionable. Most vitamins are fat soluble, but if you’re not taking in fat they won’t be as effective. Probiotics are fine to continue taking while fasting.

In 1940 the famed diabetologist Elliott Joslin estimated that about one person in every three to four hundred was diabetic, representing an enormous increase from just a few decades earlier, but it was still relatively uncommon.

One quick note: diabetes ranks as only the seventh or eighth leading cause of death in the United States, behind things like kidney disease, accidents, and Alzheimer’s disease. In 2020, a little more than one hundred thousand deaths were attributed to type 2 diabetes, a fraction of the number due to either cardiovascular disease or cancer. By the numbers, it barely qualifies as a Horseman. But I believe that the actual death toll due to type 2 diabetes is much greater and that we undercount its true impact. Patients with diabetes have a much greater risk of cardiovascular disease, as well as cancer and Alzheimer’s disease and other dementias; one could argue that diabetes with related metabolic dysfunction is one thing that all these conditions have in common.

Unlocking the Benefits of Continuous Glucose Monitors: A Comprehensive Guide Continuous Glucose Monitors (CGMs) have revolutionized diabetes management, offering real-time insights into blood sugar levels like never before. As the prevalence of diabetes continues to rise globally, understanding the significance of CGMs becomes paramount. Let's delve into the world of CGMs, exploring their benefits, functionality, and impact on diabetes care. What are Continuous Glucose Monitors? Continuous Glucose Monitors are wearable devices that continuously track glucose levels throughout the day and night. Unlike traditional glucose meters, CGMs provide real-time data, offering a comprehensive view of glucose fluctuations and trends. Benefits of Continuous Glucose Monitors Continuous Monitoring CGMs provide a continuous stream of glucose data, empowering individuals to make informed decisions about their diet, exercise, and medication. Early Detection CGMs can detect both hypo- and hyperglycemic episodes before they become severe, enabling prompt intervention. Improved Diabetes Management By providing insights into how different factors affect blood sugar levels, CGMs facilitate personalized diabetes management strategies. Enhanced Quality of Life CGMs reduce the need for frequent fingerstick testing, minimizing discomfort and improving overall quality of life for individuals with diabetes. Remote Monitoring CGMs can be integrated with smartphone apps, allowing caregivers and healthcare providers to remotely monitor glucose levels and provide timely assistance. How do Continuous Glucose Monitors Work? CGMs consist of three main components: a sensor, transmitter, and receiver/display device. Measurement of glucose levels in the interstitial fluid is performed by the sensor, which is commonly inserted beneath the skin. The transmitter sends this data to the receiver/display device, where users can view real-time glucose readings and trends. Conclusion Continuous Glucose Monitors represent a significant advancement in diabetes management, offering unparalleled insights and convenience. With their ability to provide continuous glucose monitoring, early detection of fluctuations, and personalized insights, CGMs are transforming the lives of individuals with diabetes worldwide. Embracing this technology can lead to better diabetes management, improved quality of life, and reduced risk of diabetes-related complications.

from human studies of the Horsemen: cardiovascular and cerebrovascular disease, cancer, Alzheimer’s disease and related neurodegenerative conditions, and type 2 diabetes and related metabolic dysfunction.

driving, the odds are overwhelming that you will die as a result of one of the chronic diseases of aging that I call the Four Horsemen: heart disease, cancer, neurodegenerative disease, or type 2 diabetes and related metabolic dysfunction. To achieve longevity—to live

10 Common Reasons for IVF Failure  In-vitro fertilization or IVF provides a means towards parenthood to couples struggling with natural pregnancy. Although IVF is a successful, safe, and effective technique some couples may struggle with multiple IVF failures. According to Dr Vandana Narula, MBBS, MD (Obstetrics & Gynaecology), a lot of factors contribute to the success or failure of IVF. The best infertility specialist in sector 43 Chandigarh advises you to not lose hope and discuss the opportunities with your doctor. 10 Common Reasons for IVF Failure The infertility & IVF specialist in Mohali gives the following common reasons for IVF failure: 1. Poor Sperm Quality The quality of sperm determines the quality of the embryo. Men with certain medical conditions including azoospermia or diabetes may procedure poor quality and quantity of sperm. This can either hamper the development of the embryo or lead to an abnormal embryo. 2. Low Anti-Mullerian Hormone (AMH) Values AMH is a hormone secreted by cells in the egg. A good level of AMH in the woman’s blood indicates good ovarian reserve. Women with low AMH values may procedure unhealthy eggs that may not be implanted. 3. Implantation Failure Implantation failure is one of the common causes of IVF failures. It is usually caused by: A non-receptive uterus lining, thin lining, or lining affected by genital tuberculosis. Prevailing immunological conditions make the uterine environment hostile for the embryos. The endometrium has an inbuilt mechanism to reject poor-quality embryos. 4. Poor Quality of Eggs and Embryos The quality of eggs plays a significant role in IVF failure. The quality of eggs is directly related to the age of a woman and her health. The human egg consists of 23 chromosomes. If any of these chromosomes are missing or arranged incorrectly, they can produce abnormal embryos. A woman’s age also plays a key role in the egg quality. With advancing age, the eggs become less healthy and are prone to genetic abnormalities. This can make it difficult for them to be fertilized by sperm and lead to abnormal embryos.

In recent years, Continuous Glucose Monitoring (CGM) devices have emerged as a game-changer in diabetes management, offering patients a real-time view of their glucose levels and revolutionizing the way they monitor their condition. Among the pioneers in providing these life-changing devices, Med Supply US stands out as a reliable source, offering CGMs from various renowned brands like Abbott, Dexcom, and more. This article explores the significance of CGM devices and highlights the contribution of Med Supply US in making them accessible to those in need. Understanding CGM Devices: For individuals living with diabetes, maintaining optimal blood glucose levels is crucial to prevent serious health complications. Traditionally, this involved frequent finger-prick tests, which could be inconvenient and sometimes inaccurate. CGM devices, however, have transformed this process by providing continuous and real-time glucose level readings. These devices consist of a small sensor inserted under the skin that measures glucose levels in the interstitial fluid. The data collected is then transmitted to a receiver or a smartphone app, allowing users to track their glucose levels throughout the day and night. Benefits of CGM Devices: The introduction of CGM devices has brought about a paradigm shift in diabetes management due to their numerous benefits: Real-time Monitoring: CGM devices offer a real-time insight into glucose trends, enabling users to make informed decisions about their diet, exercise, and insulin dosages. This real-time feedback empowers individuals to take timely action to maintain their glucose levels within a healthy range. Reduced Hypoglycemia and Hyperglycemia: By providing alerts for both low and high glucose levels, CGMs help users avoid dangerous hypoglycemic episodes and hyperglycemic spikes. This is particularly beneficial during sleep when such episodes might otherwise go unnoticed. Data-Driven Insights: CGM devices generate a wealth of data, including glucose trends, patterns, and even predictive alerts for potential issues. This information can be shared with healthcare providers to tailor treatment plans for optimal diabetes management. Enhanced Quality of Life: The convenience of CGM devices reduces the need for frequent finger pricks, leading to an improved quality of life for individuals managing diabetes. The constant insights also alleviate anxiety related to unpredictable glucose fluctuations. Med Supply US: Bringing Hope to Diabetes Management: Med Supply US has emerged as a prominent supplier of CGM devices, offering a range of options from reputable brands such as Abbott and Dexcom. The availability of CGMs through Med Supply US has made these cutting-edge devices accessible to a wider demographic, bridging the gap between technology and healthcare. Med Supply US not only provides access to CGM devices but also plays a crucial role in educating individuals about their benefits. Through informative resources, they empower users to make informed choices based on their specific needs and preferences. Furthermore, their commitment to customer support ensures that users can seamlessly integrate CGM devices into their daily routines.

vitamin K also makes the mitochondria function better. That is a good thing because the longer our mitochondria remain healthy, the slower we age.163 That is also one reason that sufficient intake of vitamin K decreases the risk of typical aging-related diseases, such as Alzheimer’s disease, diabetes, and cardiovascular disease.164

Exploring the Benefits of Continuous Glucose Monitors (CGMs) In the world of diabetes management, Continuous Glucose Monitors (CGMs) have emerged as a game-changing technology. These small devices are designed to provide real-time data on blood glucose levels, offering numerous advantages for individuals living with diabetes. In this article, we'll delve into the benefits of CGMs and why they are becoming an indispensable tool for managing diabetes. Real-Time Monitoring: Continuous Glucose Monitors provide a continuous stream of data, allowing users to monitor their glucose levels 24/7. This real-time feedback helps individuals make informed decisions about their diet, exercise, and insulin administration. Improved Glycemic Control: With constant glucose tracking, users can spot trends and patterns in their blood sugar levels. This insight enables them to make proactive adjustments to their diabetes management plan, leading to better glycemic control. Reduced Hypoglycemia and Hyperglycemia: CGMs can provide early warnings of impending hypoglycemia (low blood sugar) or hyperglycemia (high blood sugar), reducing the risk of severe blood sugar fluctuations and related complications.

Oxidation burns things gradually and steadily. Just as oxidation causes metal to rust and apple flesh to brown, it damages cells throughout the body by zapping DNA, scarring the walls of arteries, inactivating enzymes, and mangling proteins. Paradoxically, the more oxygen we use, the more we generate reactive oxygen species, so theoretically vigorous physical activities that consume lots of oxygen should accelerate senescence. A related driver of senescence is mitochondrial dysfunction. Mitochondria are the tiny power plants in cells that burn fuel with oxygen to generate energy (ATP). Cells in energy-hungry organs like muscles, the liver, and the brain can have thousands of mitochondria. Because mitochondria have their own DNA, they also play a role in regulating cell function, and they produce proteins that help protect against diseases like diabetes and cancer.29 Mitochondria, however, burn oxygen, creating reactive oxygen species that, unchecked, cause self-inflicted damage. When mitochondria cease to function properly or dwindle in number, they cause senescence and illness.30

the odds are overwhelming that you will die as a result of one of the chronic diseases of aging that I call the Four Horsemen: heart disease, cancer, neurodegenerative disease, or type 2 diabetes and related metabolic dysfunction. To achieve longevity—to live longer and live better for longer—we must understand and confront these causes of slow death. Longevity has two components. The first is how long you live, your chronological lifespan, but the second and equally important part is how well you live—the quality of your years. This is called healthspan,

Taken together, then, what do these two monkey studies have to tell us about nutritional biochemistry? Avoiding diabetes and related metabolic dysfunction—especially by eliminating or reducing junk food—is very important to longevity. There appears to be a strong link between calories and cancer, the leading cause of death in the control monkeys in both studies. The CR monkeys had a 50 percent lower incidence of cancer. The quality of the food you eat could be as important as the quantity. If you’re eating the SAD, then you should eat much less of it. Conversely, if your diet is high quality to begin with, and you are metabolically healthy, then only a slight degree of caloric restriction—or simply not eating to excess—can still be beneficial.

While it’s tricky to impossible to avoid or prevent the genetic mutations that help give rise to cancer, it is relatively easy to address the metabolic factors that feed it. I’m not suggesting that it’s possible to “starve” cancer or that any particular diet will magically make cancer go away; cancer cells always seem to be able to obtain the energy supply they need. What I am saying is that we don’t want to be anywhere on that spectrum of insulin resistance to type 2 diabetes, where our cancer risk is clearly elevated. To me, this is the low-hanging fruit of cancer prevention, right up there with quitting smoking. Getting our metabolic health in order is essential to our anticancer strategy.

While heart disease is the most prevalent age-related condition, it is also more easily prevented than either cancer or Alzheimer’s disease. We know a lot about how and why it begins and the manner in which it progresses. While it can’t exactly be cured or reversed the way type 2 diabetes (sometimes) can, it is relatively easy to delay if you’re smart and you get on the case early.

The medical name for this condition is Non-Alcoholic Fatty Liver Disease (NAFLD) and it describes a range of conditions in which the liver tests are abnormal in people who drink little or no alcohol. It ranges from a mild condition in which excess fat is deposited in the liver causing slightly abnormal liver tests to a more serious condition in which the fat in the liver leads to inflammation, scarring and cirrhosis, which is irreversible liver damage. NAFLD is very common and may be found in up to 1 in 5 adults. Of those with NAFLD, about 1 in 4 will develop the more serious form leading to cirrhosis. This is a very slow process and may progress over years to liver failure. It is related to obesity and as in the metabolic syndrome (see previous question) insulin resistance is the underlying cause. There

She looked exhausted. Her skin was sallow. “Are you diabetic?” I asked, studying her. “No.” She sniffed. “Are you sure?” She ate a french fry slowly. “Yes.” “Does diabetes run in your family? Do any of your relatives have it?” “I know what ‘runs in the family’ means,” she snapped. She shot me a glare and I smiled, happy she had moved from hypoglycemic to just plain hangry. “And no, nobody has it. And neither do I.” I put the straw in the top of her orange juice and handed it to her. “How do you know?” “Because I don’t have time to be diabetic, Joshua.” I scoffed. Of course.

Even vegetarians can suffer high rates of chronic disease, though, if they eat a lot of processed foods. Take India, for example. This country’s rates of diabetes, heart disease, obesity, and stroke have increased far faster than might have been expected given its relatively small increase in per capita meat consumption. This has been blamed on the decreasing “whole plant food content of their diet,” including a shift from brown rice to white and the substitution of other refined carbohydrates, packaged snacks, and fast-food products for India’s traditional staples of lentils, fruits, vegetables, whole grains, nuts, and seeds.40

For about 60 years type 1 diabetics were treated with insulin extracted from the pancreas of pigs. This wasn’t ideal as the insulin was a relatively minor component of all the proteins in the pig pancreas and required a lot of expensive purification to produce a relatively small amount of the drug. The pig insulin wasn’t quite identical to the normal human version and it wasn’t suitable for some patients. It was also very difficult to ramp up supply quickly when demand increased. In the 1980s, the drug firm Eli Lilly produced and sold human insulin that had been created in genetically modified bacteria. Now, virtually all insulin is made in bacteria or yeast.

Avi-Dekel This CBD strain has a 15.8% CBD level and 1% THC level, and with an indica-to-sativa ratio of 60:40, it delivers medicinal benefits without making the patient high. The Avi-Dekel CBD strain is relatively new and a product of Northern Israel. It is characterized by the gold-colored nuggets and olive green tones of the plant. The Avi-Dekel refreshes the body, relieves pain, and improves the mood, causing a feeling of happiness in the patient. The Avi-Dekel strain is recommended for those suffering from rheumatoid arthritis, colitis, diabetes, digestive problems, sleep disorders, and liver inflammation. The strain has a pleasant and earthy aroma, with nutty and chestnut flavors. Patients can still function normally een after taking Avi-Dekel because it does not cause drowsiness.

In 2003, epidemiologists from the Centers for Disease Control, led by Eugenia Calle, published an analysis in The New England Journal of Medicine reporting that cancer mortality in the United States was clearly associated with obesity and overweight. The heaviest men and women, they reported, were 50 and 60 percent more likely, respectively, to die from cancer than the lean. This increased risk of death held true for a host of common cancers—esophageal, colorectal, liver, gallbladder, pancreatic, and kidney cancers, as well as, in women, cancers of the breast, uterus, cervix, and ovary. In 2004, the CDC followed up with an analysis linking cancer to diabetes, particularly pancreatic, colorectal, liver, bladder, and breast cancers. Cancer researchers trying to make sense of this association would later say that something about cancer seems to thrive on the metabolic environment of the obese and the diabetic. One conspicuous clue as to what that something might be was that the same association was seen with people who weren’t obese and diabetic (or at least not yet) but suffered only from metabolic syndrome and thus were insulin-resistant. The higher their levels of circulating insulin, and that of a related hormone known as insulin-like growth factor, the greater the likelihood that they would get cancer.

Gout Every single year, thousands upon thousands of people are diagnosed with, and suffer from a condition known as gout. Gout is basically a form of severe arthritis, in various joints on the body. The ankle for instance, is especially susceptible to gout, making it a very painful condition to have to deal with. It is brought on by elevated levels of uric acid levels in the blood stream. This acid actually crystallizes, forming crystal deposits on the various joints in the body. Kind of like lime scale affects shower heads, and heating elements. There are pharmaceutical medicines and lotions etc out there, many of which are basically useless and only mildly effective at best. Many of these medicines are based on pain relief, meaning that they only mask the problems, rather than curing them. The good news is that natural remedies have been proven to be especially effective when treating gout, specifically, apple cider vinegar. A normal and perfectly healthy range of uric acid in the blood should be between 3.6 mg/dL and 8.3 mg/dL. This uric acid is perfectly normal, and all bodies produce it, the problems occur when the body can no longer remove excess levels of the acid, once it is produced. Apple cider vinegar is a proven natural remedy for a whole host of other health and beauty related conditions, and gout is no exception. With its anti-bacterial, anti-viral, and anti-fungal properties, it is being hailed by some people as a medical wonder. Apple cider vinegar helps to increase your PH levels, making your body more alkaline, this makes it especially effective at eliminating uric acid, which can lead to gout. The Malic acid contained in apple cider vinegar, helps to dissolve sodium urate crystals, the same crystals responsible for gout. To help rid you of painful gout like symptoms, how about you: Drink the water and vinegar solution at least three times daily - Simply mix three table spoons full of vinegar, with a glass of water, or even apple juice if you wish, and chug it down. Try

Glucose monitoring device A glucose monitoring device is a medical device that measures the amount of glucose in the blood. This information can be used to help people with diabetes manage their condition. There are two main types of glucose monitoring devices: blood glucose meters and continuous glucose monitors (CGMs). Blood glucose meters are the most common type of glucose monitoring device. They require a fingerstick to obtain a blood sample, which is then analyzed by the meter. Blood glucose meters are relatively inexpensive and easy to use. However, they only provide a snapshot of blood sugar levels at a particular time. CGMs are more advanced than blood glucose meters. They measure glucose levels continuously and provide real-time updates to a receiver or smartphone. CGMs can be more expensive than blood glucose meters, but they can provide valuable information about blood sugar trends that can help people with diabetes make better treatment decisions. Med Supply US offers a variety of glucose monitoring devices, including blood glucose meters and CGMs. The company's blood glucose meters are affordable and easy to use, while its CGMs provide accurate and real-time glucose readings. Med Supply US also offers a variety of accessories for glucose monitoring devices, such as lancets, test strips, and infusion sets.

Four Horsemen: heart disease, cancer, neurodegenerative disease, or type 2 diabetes and related metabolic dysfunction. To achieve longevity—to live longer and live better for longer—we must understand and confront these causes of slow death.

When should you be skeptical? Any time you see a report that a single food, beverage, supplement, food product, or ingredient causes or reduces the risk for obesity, heart disease, type 2 diabetes, or cancer, it is a good idea to envision a red warning flag flying high in the air. The studies may have identified associations between the food factor and the disease, but associations can be due to any number of other causes. Dietary patterns, not single factors, are what matter to health. Look out for words like “miracle” or “breakthrough.” Science tends to proceed in small increments and rarely works that way. And please be especially skeptical of “everything you thought you knew about nutrition is wrong.” Science does not work that way, either. Whenever you see “may” or “might”—as in “may reduce the risk of heart disease” or “might improve cognition in the elderly”—recognize that these also mean “may not” or “might not.” Overall, it is always a good idea to ask whether study results seem plausible in the light of everything else you know. As an eater, you should be wary of media hype about whether fat or sugar is a more important cause of health problems. This question ignores basic principles of nutrition: we eat foods, not nutrients, and how much we eat is often just as important as what we eat. Diets of enormous variety, from Asian diets traditionally based on rice (carbohydrates that convert to sugar in the body) to Mediterranean diets rich in olive oil (fat), can all promote long and healthy lives. The basic principles of eating healthfully have remained remarkably constant over the years: eat a wide variety of relatively unprocessed foods in reasonable amounts. Note that these same dietary principles apply to prevention of the entire range of diet-related chronic diseases. If an industry-funded study claims miraculous benefits from the sponsor’s products, think, “Advertising.

the odds are overwhelming that you will die as a result of one of the chronic diseases of aging that I call the Four Horsemen: heart disease, cancer, neurodegenerative disease, or type 2 diabetes and related metabolic dysfunction.

I learn that, in simple terms, the cells in the nerves that lead from my brain to my ear have been attacked by a virus. This has resulted in the loss of my ability to hear middle and bottom frequencies. If I’d dealt with it immediately—with a dose of my old friend cortisone, there’s the possibility of kick-starting the cells’ regeneration—it might have been different. But I left it too late, in true Collins tradition. It’s what killed my dad in the end, him not dealing with his diabetes and heart condition. Now, because this is a viral infection, the noise blast in the headphones was probably not the cause. However, as the months and years pass, it’s the only hearing-related experience I have that’s out of the ordinary, so I can’t help but feel it’s partly to blame.

Potential benefits of NMN (based on research): ● Increase energy levels and stamina ● Improve muscle strength and function ● Improve cognitive function and memory ● Protects against age-related diseases (e. g heart disease, diabetes, Alzheimer's) ● Slows down its own aging process

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metabolic syndrome of noncommunicable diseases (NCDs), account for the death of 89% of us. Fifty percent of us will die from the big two: cancer and heart disease; the rest from dementia, obesity, and diabetes-related complications, etc.

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