Chronic Kidney Disease Quotes

Health outcomes for black people are worse across the board during non-pandemic times. Black women are 22% more likely to die from heart disease than white women and 71% more likely to die from cervical cancer. Blacks are diagnosed with diabetes at a 71% higher rate than whites. Minorities receive lower quality care for their diabetes, resulting in more complications, such as chronic kidney disease and amputations. The list of conditions which Blacks suffer more extend to mental health, cancer, and heart disease.

Some diseases, such as HIV/AIDS, have slid down the list, but among the diseases whose incidence has increased the most over the past generation is chronic kidney disease. The number of deaths has doubled.14 This has been blamed on our “meat-sweet” diet.15 Excess table sugar and high-fructose corn syrup consumption is associated with increased blood pressure and uric acid levels, both of which can damage the kidney. The saturated fat, trans fat, and cholesterol found in animal products and junk food are also associated with impaired kidney function, and meat protein increases the acid load to the kidneys, boosting ammonia production and potentially damaging our sensitive kidney cells.16 This is why a restriction of protein intake is often recommended to chronic kidney disease patients to

After years of intense research, I could come to only one conclusion: People whose diets are high in animal protein have significantly higher rates of chronic diseases: hypertension, cancer, diabetes, heart disease, and many, many others, including cataracts, diverticulitis, diverticulosis, inflammatory bowel disease, gall bladder disorders, gout, hypertension, irritable bowel syndrome, kidney stones, and rheumatoid arthritis.

When Franklin D. Roosevelt signed the Social Security Act in 1935, old age was defined as sixty-five years, yet estimated life expectancy in the United States at the time was sixty-one years for males and sixty-four years for females.62 A senior citizen today, however, can expect to live eighteen to twenty years longer. The downside is that he or she also should expect to die more slowly. The two most common causes of death in 1935 America were respiratory diseases (pneumonia and influenza) and infectious diarrhea, both of which kill rapidly. In contrast, the two most common causes of death in 2007 America were heart disease and cancer (each accounted for about 25 percent of total deaths). Some heart attack victims die within minutes or hours, but most elderly people with heart disease survive for years while coping with complications such as high blood pressure, congestive heart failure, general weakness, and peripheral vascular disease. Many cancer patients also remain alive for several years following their diagnosis because of chemo-therapy, radiation, surgery, and other treatments. In addition, many of the other leading causes of death today are chronic illnesses such as asthma, Alzheimer’s, type 2 diabetes, and kidney disease, and there has been an upsurge in the occurrence of nonfatal but chronic illnesses such as osteoarthritis, gout, dementia, and hearing loss.63 Altogether, the growing prevalence of chronic illness among middle-aged and elderly individuals is contributing to a health-care crisis because the children born during the post–World War II baby boom are now entering old age, and an unprecedented percentage of them are suffering from lingering, disabling, and costly diseases. The term epidemiologists coined for this phenomenon is the “extension of morbidity.

me!” For Alexandra sitting beside him, unable to help, each cry seemed a sword thrust into the bottom of her heart. Almost worse for the Empress than the actual episodes of bleeding was the terrible Damoclean uncertainty of hemophilia. Other chronic diseases may handicap a child and dismay the mother, but in time both learn to adjust their lives to the medical facts. In hemophilia, however, there is no status quo. One minute Alexis could be playing happily and normally. The next, he might stumble, fall and begin a bleeding episode that would take him to the brink of death. It could strike at any time in any part of the body: the head, nose, mouth, kidneys, joints, or muscles. Like Queen Victoria’s, Alexandra’s natural reaction was to overprotect her child. The royal family of Spain put its hemophilic sons in padded suits and padded the trees in the park when they went out to play. Alexandra’s solution was to assign the two sailors to hover so closely over Alexis that they could reach out and catch him before he fell. Yet, as Gilliard pointed out to the Empress, this kind of protection can stifle the spirit, producing a dependent, warped and crippled mind. Alexandra responded gallantly, withdrawing the two guardians to permit her son to make his own mistakes, take his own steps and—if necessary—fall and bruise. But it was she who accepted the risk and who bore the additional burden of guilt when an accident followed. To

The impact of second-class treatment on black people’s bodies is devastating. It is manifested not only in the black–white death gap but also in the drastic measures required when chronic disease is left unmanaged. Black patients are less likely than whites to be referred to kidney and liver transplant wait lists and are more likely to die while waiting for a transplant.68 If they are lucky enough to get a donated kidney or liver, blacks are sicker than whites at the time of transplantation and less likely to survive afterward. “Take a look at all the black amputees,” said a caller to a radio show I was speaking on, identifying the remarkable numbers of people with amputated legs you see in poor black communities as a sign of health inequities. According to a 2008 nationwide study of Medicare claims, whites in Louisiana and Mississippi have a higher rate of leg amputation than in other states, but the rate for blacks is five times higher than for whites.69 An earlier study of Medicare services found that physicians were less likely to treat their black patients with aggressive, curative therapies such as hospitalization for heart disease, coronary artery bypass surgery, coronary angioplasty, and hip-fracture repair.70 But there were two surgeries that blacks were far more likely to undergo than whites: amputation of a lower limb and removal of the testicles to treat prostate cancer. Blacks are less likely to get desirable medical interventions and more likely to get undesirable interventions that good medical care would avoid.

Protein and the Story of the AGEs Advanced glycation end-products (AGEs) can do some serious damage, especially over time. An article in The Clinical Journal of the American Society of Nephrology makes several important points about protein and its relationship to many of the diseases of aging: • Human studies indicate that excess dietary protein promotes progressive kidney damage by increasing the AGE burden. • A prudent approach is to recommend that people with chronic kidney disease achieve the recommended dietary allowance of protein—0.8 g/kg per day, or about 10 percent of total caloric intake— with an emphasis on high-quality protein, low in AGEs. • Conversely, very low dietary protein intake may lead to malnutrition, especially in those with advanced chronic kidney disease. • The dietary AGE load can be minimized by consuming nonmeat proteins. • There are several culinary methods that reduce AGE formation during cooking—steaming, poaching, boiling, and stewing. Frying, broiling, or grilling should be avoided, as they promote AGE formation. • Limitation of dietary AGEs seems prudent in those with obesity, diabetes, and other risk factors for chronic kidney disease.i With the gradual onset of kidney failure, acidosis again ensues and will lead to all types of inflammation and metabolic abnormalities. The preceding recommendations for how to avoid turning a meal into AGEs should become a major agingmanagement technology for Baby Boomers everywhere. — Leonard Smith, M.D.

Calcification is the hardening of body tissues by calcium salts or deposits. Although calcification itself is not considered a disease, it has been shown to be a significant contributing factor in nearly every known illness and aging condition, including heart disease, kidney stones, gallstones, chronic inflammation, arthritis, cancers, cataracts, eczema, psoriasis, and even wrinkles.

Primary hyperparathyroidism Primary hyperparathyroidism is caused by autonomous secretion of PTH, usually by a single parathyroid adenoma which can vary in diameter from a few millimetres to several centimetres. It should be distinguished from secondary hyperparathyroidism, in which there is a physiological increase in PTH secretion to compensate for prolonged hypocalcaemia (such as in vitamin D deficiency, p. 1121), and tertiary hyperparathyroidism, in which continuous stimulation of the parathyroids over a prolonged period of time results in adenoma formation and autonomous PTH secretion (Box 20.37). This is most commonly seen in individuals with advanced chronic kidney disease (p. 487).

Magnesium’s role in bone health is multifaceted. • Adequate levels of magnesium are essential for the absorption and metabolism of calcium. • Magnesium stimulates a particular hormone, calcitonin, that helps to preserve bone structure and draws calcium out of the blood and soft tissues back into the bones, preventing some forms of arthritis and kidney stones. • Magnesium suppresses another bone hormone called parathyroid, preventing it from breaking down bone. • Magnesium converts vitamin D into its active form so that it can help calcium absorption. • Magnesium is required to activate an enzyme that is necessary to form new bone. • Magnesium regulates active calcium transport. With all these roles for magnesium to play, it is no wonder that even a mild deficiency can be a risk factor for osteoporosis. Further, if there is too much calcium in the body, especially from calcium supplementation, as in Muriel’s case, magnesium absorption can be greatly impaired, resulting in worsening osteoporosis and the likelihood of kidney stones, arthritis, and heart disease. A chance meeting in a hotel with a woman whose lymphoma worsened immediately after being prescribed 2,500 mg of calcium, but no magnesium, for her osteoporosis made me consider that excess calcium can also deposit in cancerous tumors. Other factors that are important in the development of osteoporosis include diet, drugs, endocrine imbalance, allergies, vitamin D deficiency, and lack of exercise. A detailed review of the osteoporosis literature shows that chronically low intake of magnesium, vitamin D, boron, and vitamins K, B12, B6, and folic acid leads to osteoporosis.

One way to quantify the extension of morbidity currently occurring is a metric known as disability-adjusted life years (DALYs), which measures a disease’s overall burden as the number of years lost to ill health plus death.65 According to an impressive recent analysis of medical data worldwide from between 1990 and 2010, the burden of disability caused by communicable and nutrition-related diseases has plunged by more than 40 percent, while the burden of disability caused by noncommunicable diseases has risen, especially in developed nations. As examples, DALYs have risen by 30 percent for type 2 diabetes, by 17 percent for neurological disorders, such as Alzheimer’s, by 17 percent for chronic kidney disease, by 12 percent for musculoskeletal disorders, such as arthritis and back pain, by 5 percent for breast cancer, and by 12 percent for liver cancer.66 Even after factoring in population growth, more people are experiencing more chronic disability that results from noncommunicable diseases. For the diseases just mentioned, the number of years a person can expect to live with cancer has increased by 36 percent, with heart and circulatory diseases by 18 percent, with neurological diseases by 12 percent, with diabetes by 13 percent, and with musculoskeletal diseases by 11 percent.67 To many, old age is now equated with various disabilities (and

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However, Pauling’s interest in these carotenoids and flavonoids was confined to their chemical structures and the influence of structure on optical properties; he did not address their health functions. In 1941 Pauling was diagnosed with Bright’s disease, or glomerulonephritis, which was at the time an often-fatal kidney disorder. On the advice of physicians at the Rockefeller Institute, he went to San Francisco for treatment by Thomas Addis, an innovative Stanford nephrologist. Addis prescribed a diet low in salt and protein, plenty of water, and supplementary vitamins and minerals that Pauling followed for nearly 14 years and completely recovered. This was dramatic firsthand experience of the therapeutic value of the diet. Revelations When Pauling cast about for a new research direction in the 1950s, he realized that mental illness was a significant public health problem that had not been sufficiently addressed by scientists. Perhaps his mother’s megaloblastic madness and premature death caused by B12 deficiency underlay this interest. At about this time, Pauling’s eldest son, Linus Jr., began a residency in psychiatry, which undoubtedly prompted Pauling to consider the nature of mental illness. Thanks to funding from the Ford Foundation, Pauling investigated the role of enzymes in brain function but made little progress. When he came across a copy of Niacin Therapy in Psychiatry (1962) by Abram Hoffer in 1965, Pauling was astonished to learn that simple substances needed in minute amounts to prevent deficiency diseases could have therapeutic application in unrelated diseases when given in very large amounts. This serendipitous and key event was critically responsible for Pauling’s seminal paper in his emergent medical field. Later, Pauling was especially excited by Hoffer’s observations on the survival of patients with advanced cancer who responded well to his micronutrient and dietary regimen, originally formulated to help schizophrenics manage their illness.19,20 The regimen includes large doses of B vitamins, vitamin C, vitamin E, beta-carotene, selenium, zinc, and other micronutrients. About 40 percent of patients treated adjunctively with Hoffer’s regimen lived, on average, five or more years, and about 60 percent survived four times longer than controls. These results were even better than those achieved by Scottish surgeon Ewan Cameron, Pauling’s close clinical collaborator, in Scotland. After a long and extremely productive career at Caltech,

Chronic Kidney Disease Karma Ayurveda is an ancient Ayurveda company which provides many valuable natural remedies for kidney patients which help to keep kidney problem under control.Karma Ayurveda medicine reduces dialysis, frequency at first, and sometime kidneys can be brought to its normal function.

I was riddled with memory issues that became so severe at the age of 45 that I had to apply for disability benefits. At the age of 50, my mental functioning was in decline with severe short term memory issues, concentration problems and chronic fatigue. My kidneys were testing bad on blood tests. The USA has refused all applications for occupational disease and disability benefits.

A Protein Is Not a Protein Companies are touting protein as a cure-all and for weight loss/muscle gain. They’re selling protein shakes, protein cookies, protein snack bars, even protein coffee. It’s true that protein is neither carbohydrate nor sugar nor fat, and you need it to maintain normal growth. However, your kidneys have a limited capacity to excrete the metabolic by-products of protein metabolism, and overexcretion can cause kidney damage. Therefore, protein quality is as important as protein quantity. For example, eggs and beans both contain protein, but are very different in quality. Dietary protein is made up of twenty separate amino acids strung together in different combinations and amounts. One of those amino acids, tryptophan, is rarer and therefore more important than others, because it’s the precursor of serotonin, an important brain neurotransmitter (see Chapter 19). Eggs, poultry, and fish are the best sources of this amino acid, while beans have very little. On the other hand, additional protein is needed if you’re building muscle, especially branched-chain amino acids (BCAAs; leucine, isoleucine, valine), which are 20 percent of muscle (see Chapter 18). BCAAs are in high concentration in corn products, and are what’s in those tubs of protein powder at the health food store. If you’re a bodybuilder, you need them; if you’re not a gym rat and consume excess BCAAs, your liver will take the amino groups off and turn them into organic acids, which will either be diverted into liver fat (through DNL) or into excess glucose, either of which can generate hyperinsulinemia and drive chronic disease. The goal is to get more tryptophan and less BCAAs in the protein you consume.

I was fortunate I had uncovered the protein intolerance before I became too sick to research it. I only uncovered it so quickly because it had coincided with research I was doing on hypoxic kidney damage and I was aware of the link to protein in urine. Had I gone back into a state of permanent chronic fatigue, I would have needed to move in with my parents.

What are the various kidney disorders and the treatment for them? There are many kidney-related diseases and the treatment options for kidney disease are listed below: 1. Chronic kidney disease: Treatment for CKD concentrates on controlling the root of the problem, reducing the severity of the condition, and managing symptoms. It involves changes to lifestyles including a healthy and balanced eating plan.

In Canada, an estimated one in three people lives with at least one chronic disease. Conditions that appeared to increase the risk and severity of COVID-19 included type 2 diabetes, obesity, high blood pressure and other heart conditions, chronic obstructive pulmonary disease (COPD), chronic kidney disease and cancer. All of these conditions have been shown to be associated with inadequate diets and malnutrition, either as a cause or consequence of the disease. We normally associate the word "malnutrition" with undernutrition or starvation. However, malnutrition also applies to overconsumption of calories, protein or fat and frequently results in overweight or obesity. A well-primed immune response depends on good nutrition to function, and malnutrition is known to increase susceptibility to infections. In turn, infection can aggravate malnutrition, since it increases the body's demand for nutrients. This creates a vicious cycle, further increasing vulnerability to infection. In Canada, malnutrition is much more widespread than we would like to believe. A cross-Canada study conducted in eighteen hospitals screened patients for malnutrition on admission and found 45 per cent of them to be malnourished. Those who were malnourished had significantly longer hospital stays than those who were not.

PHYSICIAN DR. J, M.D. FACP. Dr. J is an American Board Certified physician with extensive training in both outpatient and inpatient medicine. Dr. J is affiliated with all major Central Florida hospitals and also has admitting privileges to all those hospitals. In his outpatient practice, he sees patients with acute and chronic medical problems. He specializes in the management of hypertension, diabetes, hyperlipidemia, chronic kidney disease, and heart disease.

The toxic effects of acetaminophen are accelerated by alcohol use. Chronic acetaminophen use and chronic alcohol abuse have been separately linked to kidney and liver disease, according to Dr. Martin Zand, medical director of the kidney and pancreas transplant programs at the University of Rochester Medical Center in New York. If you want to give your liver a break, avoid acetaminophen.

The sheer numbers associated with chronic disease, the magnitude of the medical and financial iceberg, make a mockery of this approach. The toll of the seven most common chronic diseases, in costs and lost productivity, was $4.2 trillion in the United States in 2012, up from $1.3 trillion in 2003.4 Chronic diseases account for more than 65% of corporate health-care costs. In a single year, there were almost 0.5 million new diabetes diagnoses for Americans ages twenty to forty-four, and 1 million new diabetics aged forty-five to sixty-five. Those are just the people who felt bad enough to see a doctor. The Centers for Disease Control estimate that 79 million Americans are pre-diabetic, which means their bodies are teetering on the edge of a disease that leads to blindness, kidney failure, nerve damage, and limb amputations if it isn’t controlled.5 Those people can be pulled back from the brink to some kind of normal future if they decide to make some significant changes in their lives. Unfortunately, 65% of employers in a large 2011 survey cited the difficulty of motivating employees to change their behavior as their top health-care challenge.

Low-cost, high-frequency expenditures are those that need to be undertaken for common illnesses that occur periodically or those for the prevention and early treatment of conditions such as chronic kidney disease, cervical cancer, pre-eclampsia, suicide mortality and damage due to glaucoma. These represent small expenditures that are affordable to most people but are often not incurred by individuals either because of the twin phenomena of distorted perception and behaviour, and a gap in understanding about what they need, or because of gaps in health services delivery or access to basic financial services.

One hundred percent of the nearly 1 million pounds of chloroform released in Mobile County in 1988 was released in Africatown. Chloroform is classified as a probable carcinogen by the EPA. Chronic long-term exposure, such as one would experience living in the shadow of two paper mills, can cause liver disease and affect the central nervous system. One hundred percent of the chlorine dioxide in the county was released in Africatown. Nearly all of the 1.8 million pounds of hydrochloric acid released in the county in 1988 was released in Africatown. Nearly all of the acetone, methanol, xylene, chlorine, methyl ethyl ketone, and toluene released in the county were released in Africatown. The chemicals are linked to cancer, birth defects, fertility problems, kidney and liver damage, nose and throat irritation, asthma, and loss of hearing and color vision.

In late 1985, the Reagan White House blocked the use of CDC money for education, leaving the US behind other Western nations in telling its citizens how to avoid contracting the virus. Many Americans still thought you could get AIDS from a toilet seat or a glass of water. According to one poll, the majority of Americans supported quarantining AIDS patients. This heightened awareness set off waves of anxiety across the country, which was often express through jokes (Q: What do you call Rock Hudson in a wheelchair? A: Roll-AIDS!) and violence. Between the years 1985 and 1986, anti-gay violence increased by 42 percent in the US. Even in San Francisco, where Greyhound buses still dropped off gay men and women taking refuge from the prejudice of their hometowns, carloads of teenagers would drive through the Castro looking for targets. In December 1985, a group of teenagers, shouting “diseased faggot” and “you’re killing us all,” dragged a man named David Johnson from his car in a San Francisco parking lot. While his lover looked on in horror, the teenagers kicked and beat Johnson with their skateboards, breaking three of his ribs, bruising his kidneys, an gashing his face and neck with deep fingernail scratches.

Acidosis can lead to chronic headaches, sleepiness or even insomnia, vertigo, seizures, diarrhoea, shortness of breath, chronic cough, palpitation, indigestion, reflux, heartburn, loss of calcium in the body, weakness in the bones, dry skin and other skin disorders including rashes, acne, body odour, increased risk of formation of kidney and bladder stones, accelerated ageing, degenerative diseases, fatigue and hormonal and glandular disorders. And I have only just scraped the surface here. When

Microvascular health would not show up on a scan, but there is an interesting blood number we can use: creatinine. Creatinine is naturally produced bodily junk and one of the kidney’s tasks is to get rid of it.

Now the microvascular health of the kidneys is going to be very similar to the microvascular health everywhere else. So this one measurement is going to give us the big picture—microvascularly speaking. A creatinine level at or above about 1.2 mg/dl is bad.

The full-body scan will reveal these: Amount of heart calcium—the best non-invasive measurement of atherosclerosis. Bone density—how far are you from osteoporosis? 
 Colon problems—any early signs of colon cancer. Thoracic or abdominal aneurisms—these can be fatal and ~4% of people over 65 have one. Cancers or pre-cancerous condition in various organs—includes lungs, liver, gall bladder, spleen, kidneys, adrenal glands, etc.

These are the risk factors: chronic depression; eating disorders (anorexia nervosa, bulimia); family history of a first-degree relative with osteoporosis; in men, delayed puberty, diminished libido, erectile dysfunction, low testosterone; in women, late menarche, loss of or irregular menstrual periods, or early menopause (estrogen deficiency); low body weight (less than 127 pounds); maternal history of hip fracture; personal history of fracture related to mild-to-moderate trauma as an adult; poor health; chronic disease of the kidneys, gastrointestinal system, or lungs; sedentary lifestyle; and unhealthy lifestyle (tobacco smoke, excessive alcohol, or poor eating habits).

As we become ever more insulin-resistant and glucose-intolerant, as our blood sugar gets higher along with our insulin levels, as our blood pressure elevates and we get ever fatter, we are more likely to be diagnosed as diabetic and manifest the diseases and conditions that associate with diabetes. These include not just heart disease, gout, cancer, Alzheimer’s, and the cluster of Western diseases that Burkitt and Trowell included in their provisional list, but all the conditions typically perceived as complications of diabetes: blood-vessel (vascular) complications that lead to strokes, dementia, and kidney disease; retinopathy (blindness) and cataracts; neuropathies (nerve disorders); plaque deposits in the arteries of the heart (leading to heart attacks) or the legs and feet (leading to amputations); accumulation of advanced glycation end products, AGEs, in the collagen of our skin that can make diabetics look prematurely old, and that in joints, arteries, and the heart and lungs can cause the loss of elasticity as we age. It’s this premature aging of the skin, arteries, and joints that has led some diabetes researchers to think of the disease as a form of accelerated aging. But increasing our risk of contracting all these other chronic conditions means we’re also likely to get these ailments at ever-younger ages and thus, effectively, age faster.