Brain Stimulation Quotes

You were designed to be very smart, Max,' she told me. 'We electrically stimulated your synaptic nerve endings while your brain was developing.' (The director) And yet I still can't program my DVD player,' I said." (Max)

He thinks he's happy but it's just a nerve cell in his brain that's getting too much stimulation or too little stimulation.

- My instructors in science and technology have taught us about how the brain works. It's full of electrical impulses. It's like a computer. If you stimulate one part of the brain with an electrode, it... - They know nothing.

Whenever you squander attention on something that doesn’t put your brain through its paces and stimulate change, your mind stagnates a little and life feels dull.

Books are not something that you just read words in. They're also a tool to adjust your senses. When I'm not feeling well there are times that I can't take in what I read. When that happens, I try to think about what could be hindering my reading. There are books that I can take in smoothly even when I'm not feeling well. I try to think why. It might be something like mental tuning. What's important when you tune is the feeling of the paper that you're touching with your fingers and the momentary stimulation your brain receives when you turn pages...

Given her deafness, the auditory part of the brain, deprived of its usual input, had started to generate a spontaneous activity of its own, and this took the form of musical hallucinations, mostly musical memories from her earlier life. The brain needed to stay incessantly active, and if it was not getting its usual stimulation..., it would create its own stimulation in the form of hallucinations.

Researchers would eventually discover that autistic people stim to reduce anxiety—and also simply because it feels good. In fact, harmless forms of self-stimulation (like flapping and fidgeting) may facilitate learning by freeing up executive-functioning resources in the brain that would otherwise be devoted to suppressing them.

Multitasking has been found to increase the production of the stress hormone cortisol as well as the fight-or-flight hormone adrenaline, which can overstimulate your brain and cause mental fog or scrambled thinking. Multitasking creates a dopamine-addiction feedback loop, effectively rewarding the brain for losing focus and for constantly searching for external stimulation. To make matters worse, the prefrontal cortex has a novelty bias, meaning that its attention can be easily hijacked by something new—the proverbial shiny objects

From dopamine’s point of view, having things is uninteresting. It’s only getting things that matters. If you live under a bridge, dopamine makes you want a tent. If you live in a tent, dopamine makes you want a house. If you live in the most expensive mansion in the world, dopamine makes you want a castle on the moon. Dopamine has no standard for good, and seeks no finish line. The dopamine circuits in the brain can be stimulated only by the possibility of whatever is shiny and new, never mind how perfect things are at the moment. The dopamine motto is “More.

A powerful AI system tasked with ensuring your safety might imprison you at home. If you asked for happiness, it might hook you up to a life support and ceaselessly stimulate your brain's pleasure centers. If you don't provide the AI with a very big library of preferred behaviors or an ironclad means for it to deduce what behavior you prefer, you'll be stuck with whatever it comes up with. And since it's a highly complex system, you may never understand it well enough to make sure you've got it right.

Your body produces some chemicals that stimulate some nerves that send a signal to your brain saying 'Oh my God, I am going to die,' and that's how you get pain.

You hate him worse than me, you viper,’ he whispered as the stimulant cleared his brain. ‘Aye, lord, but here’s the oddity of it - I love him too.’ Morgan replied, her eyes void of all emotion.

Any form of negative rumination—for example, worrying about your financial future or health—will stimulate the release of destructive neurochemicals.

The mind and body are linked together in a meshwork of oxygen, nutrients, hormones, and neuron health. Physical exercise drives that meshwork, stimulating the brain and freeing one’s intellect.

Pull up a weed from the wet soil of the drenched garden and smell the rich life the earthworm has left behind. Just a whiff of it will flood you with a feeling of well-being. The microbes in freshly turned soil stimulate serotonin production, working on the human brain the same way antidepressants do.

The British researchers found that it takes a lot of money to beat out the most rewarding smiles we see. In the case of this study, it took up to 16,000 pounds sterling in cash to generate the same level of brain stimulation as one smile! This

When we constantly fill up all our "empty" time with stimulation in the form of electronic devices, games, and distractions, our brains become disengaged and the thinking process is effectively halted. We never get to hear our own inner voice-we don't develop a relationship with ourselves and our minds. We don't get to know who we are because we're not listening.

Researchers have known for some time now that the cornerstone of all degenerative conditions, including brain disorders, is inflammation. But what they didn’t have documented until now are the instigators of that inflammation—the first missteps that prompt this deadly reaction. And what they are finding is that gluten, and a high-carbohydrate diet for that matter, are among the most prominent stimulators of inflammatory pathways that reach the brain.

Pornography causes release of adrenaline from an area in the brain called the locus coeruleus, and this makes the heart race in those who view, or even anticipate, viewing pornography. The sexual pleasure of pornography may be partially caused by release of dopamine from the ventral tegmental area, and this stimulates the nucleus accumbens, one of the key pleasure centers of the brain.

Every time you take in the sense of feeling safe, satisfied, or connected, you stimulate responsive circuits in your brain.

Though introverts look calm on the surface, our brains are bubbling with activity, and thus we require less external stimulation than extroverts.

Building an Alzheimer’s-resistant brain through cognitive stimulation means learning to play piano, meeting new friends, traveling to a new city, or reading this book. You’re welcome.

The Emory University neuroscientists James Rilling and Gregory Berns found that helping people in need stimulates the same brain region as winning a prize or eating a delicious meal. We also know that depressed (and formerly depressed) people are more likely to see the world from others’ points of view and to experience compassion; conversely, high-empathy people are more likely than others to enjoy sad music.

As we age and plasticity declines, it becomes increasingly difficult for us to change in response to the world, even if we want to. We find familiar types of stimulation pleasurable; we seek out like-minded individuals to associate with, and research shows we tend to ignore or forget, or attempt to discredit, information that does not match our beliefs, or perception of the world, because it is very distressing and difficult to think and perceive in unfamiliar ways. Increasingly the aging individual acts to preserve the structures within, and when there is a mismatch between his internal neurocognitive structures and the world, he seek to change the world. In small ways he begins to micromanage his environment, to control it, and make it familiar. But this process, writ large, often leads whole cultural groups to try to impose their view of the world on other cultures, and they often become violent, especially in the modern world, where globalization has brought different cultures closer together, exacerbating the problem. Wexler's point, then, is that much of the cross-cultural conflict we see is a product of the relative decrease in plasticity. One could add that totalitarian regimes seem to have an intuitive awareness that it becomes hard for people to change after a certain age, which is why so much effort is made to indoctrinate the young from an early age.

Testosterone also increases confidence and optimism, while decreasing fear and anxiety.5 This explains the “winner” effect in lab animals, where winning a fight increases an animal’s willingness to participate in, and its success in, another such interaction. Part of the increased success probably reflects the fact that winning stimulates testosterone secretion, which increases glucose delivery and metabolism in the animal’s muscles and makes his pheromones smell scarier. Moreover, winning increases the number of testosterone receptors in the bed nucleus of the stria terminalis (the way station through which the amygdala communicates with the rest of the brain), increasing its sensitivity to the hormone. Success in everything from athletics to chess to the stock

At the most elementary level of information processing, stimulation is energy, and my brain needed to be protected, and isolated from obnoxious sensory stimulation, which it perceived as noise.

The very definition of an addictive drug is one that stimulates the mesolimbic pathway, but there are three general axioms in psychopharmacology that also apply to all drugs: 1. All drugs act by changing the rate of what is already going on. 2. All drugs have side effects. 3. The brain adapts to all drugs that affect it by counteracting the drug’s effects.

The bottom line is this: environmental toxins are all around us, and they stimulate the production of free radicals, which can cause axidative damage to any kind of cell, be it muscle, nerve, liver, kidney,, heart, brain, and so on, and cause autoimmune disease.

Like a bee in a flower bed, the human brain naturally flits from one thought to the next. In the high-speed workplace, where data and headlines come thick and fast, we are all under pressure to think quickly. Reaction, rather than reflection, is the order of the day. To make the most of our time, and to avoid boredom, we fill up every spare moment with mental stimulation…Keeping the mind active makes poor use of our most precious resource. True, the brain can work wonders in high gear. But it will do so much more if given the chance to slow down from time to time. Shifting the mind into lower gear can bring better health, inner calm, enhanced concentration and the ability to think more creatively.

...ideas are definitely unstable, they not only CAN be misused, they invite misuse--and the better the idea the more volatile it is. That's because only the better ideas turn into dogma, and it is this process whereby a fresh, stimulating, humanly helpful idea is changed into robot dogma that is deadly. In terms of hazardous vectors released, the transformation of ideas into dogma rivals the transformation of hydrogen into helium, uranium into lead, or innocence into corruption. And it is nearly as relentless. The problem starts at the secondary level, not with the originator or developer of the idea but with the people who are attracted by it, who adopt it, who cling to it until their last nail breaks, and who invariably lack the overview, flexibility, imagination, and most importantly, sense of humor, to maintain it in the spirit in which it was hatched. Ideas are made by masters, dogma by disciples, and the Buddha is always killed on the road. There is a particularly unattractive and discouragingly common affliction called tunnel vision, which, for all the misery it causes, ought to top the job list at the World Health Organization. Tunnel vision is a disease in which perception is restricted by ignorance and distorted by vested interest. Tunnel vision is caused by an optic fungus that multiplies when the brain is less energetic than the ego. It is complicated by exposure to politics. When a good idea is run through the filters and compressors of ordinary tunnel vision, it not only comes out reduced in scale and value but in its new dogmatic configuration produces effects the opposite of those for which it originally was intended. That is how the loving ideas of Jesus Christ became the sinister cliches of Christianity. That is why virtually every revolution in history has failed: the oppressed, as soon as they seize power, turn into the oppressors, resorting to totalitarian tactics to "protect the revolution." That is why minorities seeking the abolition of prejudice become intolerant, minorities seeking peace become militant, minorities seeking equality become self-righteous, and minorities seeking liberation become hostile (a tight asshole being the first symptom of self-repression).

The feelings of excitement, enthusiasm, and energy dissipate. Dopamine has shut down. Dopamine circuits don’t process experience in the real world, only imaginary future possibilities. For many people it’s a letdown. They’re so attached to dopaminergic stimulation that they flee the present and take refuge in the comfortable world of their own imagination. “What will we do tomorrow?” they ask themselves as they chew their food, oblivious to the fact that they’re not even noticing this meal they had so eagerly anticipated. To travel hopefully is better than to arrive is the motto of the dopamine enthusiast.

If you want to see philosophy in action, pay a visit to a robo-rat laboratory. A robo-rat is a run-ofthe-mill rat with a twist: scientists have implanted electrodes into the sensory and reward areas in the rat’s brain. This enables the scientists to manoeuvre the rat by remote control. After short training sessions, researchers have managed not only to make the rats turn left or right, but also to climb ladders, sniff around garbage piles, and do things that rats normally dislike, such as jumping from great heights. Armies and corporations show keen interest in the robo-rats, hoping they could prove useful in many tasks and situations. For example, robo-rats could help detect survivors trapped under collapsed buildings, locate bombs and booby traps, and map underground tunnels and caves. Animal-welfare activists have voiced concern about the suffering such experiments inflict on the rats. Professor Sanjiv Talwar of the State University of New York, one of the leading robo-rat researchers, has dismissed these concerns, arguing that the rats actually enjoy the experiments. After all, explains Talwar, the rats ‘work for pleasure’ and when the electrodes stimulate the reward centre in their brain, ‘the rat feels Nirvana’. To the best of our understanding, the rat doesn’t feel that somebody else controls her, and she doesn’t feel that she is being coerced to do something against her will. When Professor Talwar presses the remote control, the rat wants to move to the left, which is why she moves to the left. When the professor presses another switch, the rat wants to climb a ladder, which is why she climbs the ladder. After all, the rat’s desires are nothing but a pattern of firing neurons. What does it matter whether the neurons are firing because they are stimulated by other neurons, or because they are stimulated by transplanted electrodes connected to Professor Talwar’s remote control? If you asked the rat about it, she might well have told you, ‘Sure I have free will! Look, I want to turn left – and I turn left. I want to climb a ladder – and I climb a ladder. Doesn’t that prove that I have free will?

The things most people need to learn in therapy are related to attachment, abandonment, love, and fear. We are trying to access basic emotional processes that are organized in primitive and early-developing parts of the brain. The language of these emotions is also very basic; it is the language of childhood. The more complex the language and ideas you bring into therapy, the more likely you are to stimulate your clients’ intellectualizing defenses.

If you stimulate seizures in an animal every day, the seizures eventually become automatic; the animal will go on having them once a day even if you withdraw the stimulation. In much the same way, the brain that has gone into depression a few times will continue to return to depression over and over. This suggests that depression, even if it is occasioned by external tragedy, ultimately changes the structure, as well as the biochemistry, of the brain.

Recent experiments in neuroscience support the view that it is our physical brain, following the known laws of science, that determines our actions, and not some agency that exists outside those laws. For example, a study of patients undergoing awake brain surgery found that by electrically stimulating the appropriate regions of the brain, one could create in the patient the desire to move the hand, arm or foot, or to move the lips and talk. It is hard to imagine how free will can operate if our behaviour is determined by physical law, so it seems that we are no more than biological machines and that free will is just an illusion.

stimulation of the medial frontal cortex gives one the feeling of the urge to move

Nothing stimulates the brain cells like a desire to wipe out the other side.

. . . never seen him inspired by any more dangerous stimulant than strong coffee, of which he was very fond & of which [he] drank freely. MacIntosh says that the measure of a man's brain is the amount of coffee he can drink with impunity. SARAH HELEN WHITMAN (POE'S FIANCÉE) TO JOHN INGRAM DECEMBER 13, 1874

Doubting free will is not just a philosophical exercise. It has practical implications. If organisms indeed lack free will, it implies that we can manipulate and even control their desires using drugs, genetic engineering or direct brain stimulation.

So, you wanna know what I want? I want it all. I want to be in love so much it hurts. The frissons. The pin pricks. The mind-blowing sex. The connection. And I want to be married with kids I adore and a husband who makes me feel safe, sexy, smart, secure, silly, serious, salacious, sinful, serene, satisfied. I want someone who makes me laugh until milk comes out of my nose (only I don’t drink milk). I want to finish someone’s sentences. I want to believe in someone, in something, in a future that’s not just about laundry and soccer practice and subdivisions and minivans and guilt-tripping grandparents. I want to make someone a better person. I want to be a good example. I want to love some kids into the world. I want someone who stimulates my brain as much as my body. I want to taste everything and go everywhere. I want to give and I want to get. I want too much and I want it all in one person.

Recovery through sleep isn’t going to happen if the majority of the components of your being aren’t getting enough stimulation or resistance to work against. Your brain may be tired after work, but if your body and emotions haven’t been challenged through the day, they’re going to keep irritating you even if you’re asleep. They don’t need rest; they need work for real recovery to take place.

Between the stimulation received from the environment and our response, certain processes had to occur inside the brain, and cognitive researchers revealed the human mind to be a great interpreting machine that made patterns and created sense of the world outside, forming maps of reality.

Cynicism is popular because it stimulates the brain chemicals that make you feel good. It stimulates dopamine by making the world feel predictable. It triggers serotonin by making you feel superior to “the jerks.” It triggers oxytocin by telling you who to trust. You pay a high price for these moments, unfortunately, because cynicism keeps you focused on problems instead of opportunities.

As we age and plasticity declines, it becomes increasingly difficult for us to change in response to the world, even if we want to. We find familiar types of stimulation pleasurable; we seek out like-minded individuals to associate with, and research shows we tend to ignore or forget, or attempt to discredit, information that does not match our beliefs, or perception of the world, because it is very distressing and difficult to think and perceive in unfamiliar ways.

More recently, these electrodes have targeted a new area of the brain (called Brodmann’s area number 25) that is often overactive in depressed patients who do not respond to psychotherapy or drugs. Deep brain stimulation has given almost miraculous relief after decades of torment and agony for these long-suffering patients.

Talking to oneself is a recognized means to learn, in fact, self-speak may be the seed concept behind human consciousness. Private conversation that we hold with ourselves might represent the preeminent means to provoke the speaker into thinking (a form of cognitive auto-stimulation), modify behavior, and perhaps even amend the functional architecture of the plastic human brain. Writing out our private talks with oneself enables a person to “see” what they think, a process that invites reflection, ongoing thoughtful discourse with the self, and refinement of our thinking patterns and beliefs. Internal sotto voice conversations with our private-self provide several advantages, but most people find it difficult to maintain self-speak for an extended period. Internal dialogue must compete with external distractions. Writing allows a person to resume a personal dialogue where they left off before interrupted by outside stimuli. A written disquisition also provides a permanent record that a person can examine, amend, supplement, update, or reject.

Indeed, excessive stimulation seems to impede learning: a recent study found that people learn better after a quiet stroll through the woods than after a noisy walk down a city street. Another study, of 38,000 knowledge workers across different sectors, found that the simple act of being interrupted is one of the biggest barriers to productivity. Even multitasking, that prized feat of modern-day office warriors, turns out to be a myth. Scientists now know that the brain is incapable of paying attention to two things at the same time. What looks like multitasking is really switching back and forth between multiple tasks, which reduces productivity and increases mistakes by up to 50 percent.

As we will see, finding words to describe what has happened to you can be transformative, but it does not always abolish flashbacks or improve concentration, stimulate vital involvement in your life or reduce hypersensitivity to disappointments and perceived injuries.

Dopamine and constant stimulation can impair your ability to think long term

Most children suffer from a crippling lack of stimulation. The brain is like any other muscle; use it, and it develops. Ignore it, and it atrophies.

Minds were human (barely), but they were so much bigger than ordinary brains, they needed stimulation in order to keep from going completely insane.

Surprise stimulates the brain, and research shows that people who do new things and visit new places—even something as modest as a trip to a new restaurant—tend to be happier.

I had a conversation with myself and three other people this morning and I did the talking for all of us. The conscious committee in my head meets once again.

Nothing is more important than your potential. Not your phone, not the TV, not anything that is begging to stimulate your brain’s reward system right now.

By removing every object of attention that’s potentially more stimulating and attractive than what you intend to do, you give your brain no choice but to work on that task.

If organisms indeed lack free will, it implies that we can manipulate and even control their desires using drugs, genetic engineering or direct brain stimulation.

The neuroplastic brain evolved in ambulatory beings who ranged around the world, always having to explore unknown territories. In other words, the brain evolved to learn. As people become immobile, they see less, hear less, and process less new information, and their brains begin to atrophy from the lack of stimulation (unless they are fundamentally thinkers, and even then the neuroplastic systems require physical movement to generate new cells and nerve growth factor).

Exercise has a direct brain connection, when you consider what it actually does. What we tend to overlook are the feedback loops that connect the brain to every cell in the body. Therefore when you throw a ball, run on a treadmill, or jog along the shore, billions of cells are "seeing" the outside world. The chemicals transmitted form the brain are acting the way sense organs do, making contact with the outside world and offering stimulation from that world. This is why the jump from being sedentary to doing a minimal amount of exercise - such as walking, light gardening, and climbing the stairs instead of taking the elevator - is so healthy. Your cells want to be part of the world.

There are already cardiac pacemakers that can sense the beat of the human heart; only when there is the slightest hint of fibrillation does the pacemaker stimulate the heart. This is a mild but very useful sort of machine intelligence. I cannot imagine the wearer of this device resenting its intelligence. I

This is what learning does. It gives us more things to think about so we have less time to get bored, depressed and under-stimulated. It builds on our existing knowledge and expands it. IT leads us to make more connections by linking together more neural pathways. It also connects our brains to other people's brains.

To avoid arousal more generally, women were instructed to get plenty of fresh air, avoid stimulating pastimes like reading and card games, and above all never to use their brains more than was strictly necessary.

Reading allows us to traverse time, space, one’s own consciousness. It engages the mind like nothing else, stimulating every part of the brain and allowing the reader to experience everything as if they were truly there.

Our cells stimulate our pain receptors in order to get our brain to focus and pay attention. Once my brain acknowledges the existence of the pain, then it has served its purpose and either lightens up in intensity, or goes away.

Experiencing empathy, the freedom to explore, trust, and insight can reset your default reactions to a more curious, tolerant, and confident stance. Because our brains are plastic, consistently positive experiences do stimulate existing neurons to adapt and connect in different pathways. Nurturing relationships help us grow psychologically and neurally in ways that are not possible in nonnurturing relationships. As adults, our most important opportunity for a nurturing relationship comes through committed partnership. It’s a breakthrough to realize that the purpose of committed relationship is not to be happy, but to heal. And then you will be happy!

From dopamine’s point of view, having things is uninteresting. It’s only getting things that matters. If you live under a bridge, dopamine makes you want a tent. If you live in a tent, dopamine makes you want a house. If you live in the most expensive mansion in the world, dopamine makes you want a castle on the moon. Dopamine has no standard for good, and seeks no finish line. The dopamine circuits in the brain can be stimulated only by the possibility of whatever is shiny and new, never mind how perfect things are at the moment.

Sex becomes less and less pleasurable in a relationship over time. Your brain gets habituated to the sensual stimulation from your specific partner as you are exposed to it repeatedly. It doesn’t mean that the love is gone from the relationship. Love still exists beyond the barriers of time, in the form of attachment, which becomes independent of sexual intimacy after the euphoric stage of mad love.

People who live with ADHD are at high risk of addiction, especially adolescents, because of their poorly functioning frontal lobes. Years ago, when the illness was less well understood, doctors and parents were reluctant to give these vulnerable children addictive drugs such as Ritalin and amphetamine. It sounded reasonable: don’t give addictive substances to people at risk for addiction. But rigorous testing showed unambiguously that adolescents who were treated with stimulant drugs were less likely to develop addictions. In fact, those who started the drug at the youngest age and took the highest doses were the least likely to develop problems with illicit drugs. Here’s why: if you strengthen the dopamine control circuit, it’s a lot easier to make wise decisions. On the other hand, if effective treatment is withheld, the weakness of the control circuit is not corrected. The desire circuit acts unopposed, increasing the likelihood of high-risk, pleasure-seeking behavior.

It all boils down to stimulation. At its core, the ADHD brain is wired to seek stimulation. We must have it in order to feel “right,” so our brains are always scanning for the bigger, better offer. While the typical understanding of ADHD suggests that people who have it are overstimulated, the ADHD brain is actually chronically understimulated. It just needs more input than a neurotypical brain to keep it humming, so what appears to be a lack of attention or impulse control is really just a desire to get to a baseline level of stimulation that keeps our brains happy.

A person can feel pleasure without any effort, if the appropriate centers in his brain are electrically stimulated, or as a result of the chemical stimulation of drugs. But it is impossible to enjoy a tennis game, a book, or a conversation unless attention is fully concentrated on the activity.

After he had sailed around the Mediterranean in 1869, Mark Twain said that travel was “fatal to prejudice, bigotry, and narrow-mindedness.” Neuroscientists have been trying for years to pin down what it is about travel that alters us, how it effects mental change. Neural pathways become ingrained, automatic, if they operate only by habit. They are highly attuned to alterations, to novelty. New sights, sounds, languages, tastes, smells stimulate different synapses in the brain, different message routes, different webs of connection, increasing our neuroplasticity. Our brains have evolved to notice differences in our environment: it’s how we’re alerted to predators, to potential danger. To be sensitive to change, then, is to ensure survival.

The problem is that we’re finding out that romantic love is kind of like cocaine. Like, frighteningly similar to cocaine. Like, stimulates the exact same parts of your brain as cocaine. Like, gets you high and makes you feel good for a while but also creates as many problems as it solves, as does cocaine.

But the female mind has demonstrated a capacity for all the mental acquirements and achievements of men, and as generations ensue that capacity will be expanded; the average woman will be as well educated as the average man, and then better educated, for the dormant faculties of her brain will be stimulated to an activity that will be all the more intense and powerful because of centuries of repose. Woman will ignore precedent and startle civilization with their progress.

Lithium regulates the proteins that control the body’s inner clock. This clock runs, oddly, on DNA, inside special neurons deep in the brain. Special proteins attach to people’s DNA each morning, and after a fixed time they degrade and fall off. Sunlight resets the proteins over and over, so they hold on much longer. In fact, the proteins fall off only after darkness falls—at which point the brain should “notice” the bare DNA and stop producing stimulants. This process goes awry in manic-depressives because the proteins, despite the lack of sunlight, remain bound fast to their DNA. Their brains don’t realize they should stop revving. Lithium helps cleave the proteins from DNA so people can wind down. Notice that sunlight still trumps lithium during the day and resets the proteins; it’s only when the sunlight goes away at night that lithium helps DNA shake free. Far from being sunshine in a pill, then, lithium acts as “anti-sunlight.” Neurologically, it undoes sunlight and thereby compresses the circadian clock back to twenty-four hours—preventing both the mania bubble from forming and the Black Tuesday crash into depression.

My favorite definition of fear is “False Expectations Appearing Real,” and when I allow myself to remember that all of my thoughts are merely fleeting physiology, I feel less moved when my story-teller goes haywire and my circuitry is triggered. At the same time, when I remember that I am at one with the universe, then the concept of fear loses its power. To help protect myself from having a trigger-happy anger or fear response, I take responsibility for what circuitry I purposely exercise and stimulate. In an attempt to diminish the power of my fear/anger response, I intentionally choose not to watch scary movies or hang out with people whose anger circuitry is easily set off. I consciously make choices that directly impact my circuitry. Since I like being joyful, I hang out with people who value my joy.

There's a reason we can't look away [from water]. Psycologists call it a 'soft fascination': the sight and sound of moving water is sufficiently stimulating to occupy the brain, but irregular enough that it doesn't become hypnotic or monotonous. It hold attention without dominating thought, freeing the mind to swim elsewhere.

I was diagnosed with ADHD in my mid fifties and I was given Ritalin and Dexedrine. These are stimulant medications. They elevate the level of a chemical called dopamine in the brain. And dopamine is the motivation chemical, so when you are more motivated you pay attention. Your mind won't be all over the place. So we elevate dopamine levels with stimulant drugs like Ritalin, Aderall, Dexedrine and so on. But what else elevates Dopamine levels? Well, all other stimulants do. What other stimulants? Cocaine, crystal meth, caffeine, nicotine, which is to say that a significant minority of people that use stimulants, illicit stimulants, you know what they are actually doing? They're self-medicating their ADHD or their depression or their anxiety. So on one level (and we have to go deeper that that), but on one level addictions are about self-medications. If you look at alcoholics in one study, 40% of male adult alcoholics met the diagnostic criteria for ADHD? Why? Because alcohol soothes the hyperactive brain. Cannabis does the same thing. And in studies of stimulant addicts, about 30% had ADHD prior to their drug use. What else do people self-medicate? Someone mentioned depression. So, if you have been treated for depression, as I have been, and you were given a SSRI medication, these medications elevate the level of another brain chemical called serotonin, which is implicated in mood regulation. What else elevates serotonin levels temporarily in the brain? Cocaine does. People use cocaine to self-medicate depression. People use alcohol, cannabis and opiates to self-medicate anxiety. Incidentally people also use gambling or shopping to self-medicate because these activities also elevate dopamine levels in the brain. There is no difference between one addiction and the other. They're just different targets, but the brain systems that are involved and the target chemicals are the same, no matter what the addiction. So people self-medicate anxiety, depression. People self-medicate bipolar disorder with alcohol. People self-medicate Post-Traumatic-Stress-Disorder. So, one way to understand addictions is that they're self-medicating. And that's important to understand because if you are working with people who are addicted it is really important to know what's going on in their lives and why are they doing this. So apart from the level of comfort and pain relief, there's usually something diagnosible that's there at the same time. And you have to pay attention to that. At least you have to talk about it.

The complex tactile movement of writing by hand stimulates our mind more effectively than typing. It activates multiple regions of the brain simultaneously, thereby imprinting what we learn on a deeper level. As a result, we retain information longer than we would by tapping it into an app.18 In one study, college students who were asked to take lecture notes by hand tested better on average than those who had typed out their notes. They were also able to better retain this information long after the exam.

If you strip sex down to its physical components, it’s an act during which a man inserts a rod-shaped mass of engorged tissue into a woman’s lubricated cavity, also made of tissue. A man rubs his rod in and out, stimulating pleasure receptors in his brain until it decides to eject a genetic package that’s important in continuing the species.

Composing artwork stimulates symbolic processing centers in the brain.

Movement stimulates our brains in ways we don't appreciate

48. Why didn’t the lamp sink?

Without an environment with emotional care and cognitive stimulation, the human brain cannot develop normally.

When you’re judging, you’re not listening. And if you’re not listening, you’re missing out on one of the best ways to stimulate your smart vagus pathway and turn down the volume of your stress-response system. But if you’re not judging, you can listen more and feel calmer, and this, in turn, will make interacting with others much easier and judging others less necessary.

mental activity such as directing attention, actually shape the structure of the brain?” As we’ve seen, experience means neural firing. When neurons fire together, the genes in their nuclei—their master control centers—become activated and “express” themselves. Gene expression means that certain proteins are produced. These proteins then enable the synaptic linkages to be constructed anew or to be strengthened. Experience also stimulates the production of myelin, the fatty sheath around axons, resulting in as much as a hundredfold increase in the speed of conduction down the neuron’s length. And as we now know, experience can also stimulate neural stem cells to differentiate into wholly new neurons in the brain. This neurogenesis, along with synapse formation and myelin growth, can take place in response to experience throughout our lives. As discussed before, the capacity of the brain to change is called neuroplasticity We are now discovering how the careful focus of attention amplifies neuroplasticity by stimulating the release of neurochemicals that enhance the structural growth of synaptic linkages among the activated neurons.

Sleep hygiene is a set of practices sleep experts recommend to obtain quality rest on a daily basis. Recommendations include low levels of stimulation in the evening, exercise and exposure to lots of natural light during the day, banning electronics from the bedroom, and sticking to a regular sleep-wake schedule. Children and teens who are stressed tend to have poor sleep hygiene if left to their own devices.

Imagine a brain floating in a tank with millions and millions of electrodes attached to specific nerve centers. Now imagine these electrodes being selectively stimulated by a computer to cause the brain to believe that it was walking down Hollywood Boulevard chomping on a hamburger and checking out the chicks.

Now, if there was a technological foul-up, or if the tapes got jumbled, the brain would suddenly see Jesus Christ pass by down Hollywood Boulevard on his way to Golgotha, pursued by a crowd of angry people, being whipped along by seven Roman Centurions.

The brain would say, "Now hold on there!" And suddenly the entire image would go "pop" and disappear.

I've always had this funny feeling about reality. It just seems very feeble to me sometimes. It doesn't seem to have the substantiality that it's suppose to have.

Winning the love of a higher-status person is a widespread strategy for stimulating serotonin. Of course, we don’t consciously equate love with status. But when a highstatus person of the right gender notices you, your brain lights up. Your neurochemistry screams “Go toward this. It is very good for your survival. ” Even bonobos, the apes known for their sexual dynamism, compete vigorously for high-status partners

a study of patients undergoing awake brain surgery found that by electrically stimulating the appropriate regions of the brain, one could create in the patient the desire to move the hand, arm, or foot, or to move the lips and talk. It is hard to imagine how free will can operate if our behavior is determined by physical law, so it seems that we are no more than biological machines and that free will is just an illusion.

Lithium regulates the proteins that control the body’s inner clock. This clock runs, oddly, on DNA, inside special neurons deep in the brain. Special proteins attach to people’s DNA each morning, and after a fixed time they degrade and fall off. Sunlight resets the proteins over and over, so they hold on much longer. In fact, the proteins fall off only after darkness falls—at which point the brain should “notice” the bare DNA and stop producing stimulants. This process goes awry in manic-depressives because the proteins, despite the lack of sunlight, remain bound fast to their DNA. Their brains don’t realize they should stop revving.

mothers suffered from major nausea and vomiting during pregnancy. When the children reached school age, 21 percent scored 130 or more points on a standard IQ test, a level considered gifted. If their mothers had no morning sickness, only 7 percent of kids did that well. The researchers have a theory—still to be proven—about why. Two hormones that stimulate a woman to vomit may also act like neural fertilizer for the developing brain.

Over the years, I've moved through alternating cycles of personal neglect and nourishment. Sometimes it's just easier to give in and allow my life to become utterly consumed by the menial and trivial than to justify or assert my individual needs. Then, disgusted with my malaise, I rise up, spurred to action by a resurgence of energy, determined to find new ways of incorporating creative expression into my life without upsetting the domestic applecart. Like a salmon's impulse to swim upstream, the urge to improve my mind and keep my brain stimulated with fresh experiences and challenges seems innate, almost primal. Struggling for my inner life, I know I must keep oxygen flowing through my intellectual gills or I will die. Pushing against stagnation and opposing currents, I swim for mental survival, obsessed with reaching some instinctual goal and preserving my sanity.

If thou fill thy brain with Boston and New York, with fashion and covetousness, and wilt stimulate thy jaded senses with wine and French coffee, thou shalt find no radiance of wisdom in the lonely waste of the pinewoods.

Environmental influences also affect dopamine. From animal studies, we know that social stimulation is necessary for the growth of the nerve endings that release dopamine and for the growth of receptors that dopamine needs to bind to in order to do its work. In four-month-old monkeys, major alterations of dopamine and other neurotransmitter systems were found after only six days of separation from their mothers. “In these experiments,” writes Steven Dubovsky, Professor of Psychiatry and Medicine at the University of Colorado, “loss of an important attachment appears to lead to less of an important neurotransmitter in the brain. Once these circuits stop functioning normally, it becomes more and more difficult to activate the mind.” A neuroscientific study published in 1998 showed that adult rats whose mothers had given them more licking, grooming and other physical-emotional contact during infancy had more efficient brain circuitry for reducing anxiety, as well as more receptors on nerve cells for the brain’s own natural tranquilizing chemicals. In other words, early interactions with the mother shaped the adult rat’s neurophysiological capacity to respond to stress. In another study, newborn animals reared in isolation had reduced dopamine activity in their prefrontal cortex — but not in other areas of the brain. That is, emotional stress particularly affects the chemistry of the prefrontal cortex, the center for selective attention, motivation and self-regulation. Given the relative complexity of human emotional interactions, the influence of the infant-parent relationship on human neurochemistry is bound to be even stronger. In the human infant, the growth of dopamine-rich nerve terminals and the development of dopamine receptors is stimulated by chemicals released in the brain during the experience of joy, the ecstatic joy that comes from the perfectly attuned mother-child mutual gaze interaction. Happy interactions between mother and infant generate motivation and arousal by activating cells in the midbrain that release endorphins, thereby inducing in the infant a joyful, exhilarated state. They also trigger the release of dopamine. Both endorphins and dopamine promote the development of new connections in the prefrontal cortex. Dopamine released from the midbrain also triggers the growth of nerve cells and blood vessels in the right prefrontal cortex and promotes the growth of dopamine receptors. A relative scarcity of such receptors and blood supply is thought to be one of the major physiological dimensions of ADD. The letters ADD may equally well stand for Attunement Deficit Disorder.

According to Genevieve, men viewed women with lips like Francine’s as more sensual than women with Genevieve’s average lips. She’d dismissed the male interest as reptilian brain activity and a lack of frontal lobe stimulation.

First, when you try to restrict calories and exercise more, your body is hardwired to perceive a starvation situation. That makes you tired (so you move less and conserve energy) and hungry (so you eat more), and it slows down your metabolism (so you don’t die!). This “eat less, exercise more” formula is not too successful for most people. It can work for a short time, certainly, but less than 10 percent of people lose weight and keep it off for a year;4 you will almost always rebound and gain back the weight. Second, when you eat carbs and sugar, insulin spikes and your blood sugar drops. The insulin drives most of the available fuel in your bloodstream into fat cells, especially the fat cells around your middle, otherwise known as belly fat. So your body is starved of fuel, and this stimulates your brain5 to make you eat more.6 You could have a year’s worth of stored energy in your fat tissue and yet feel like you are starving. The only thing that can stop this vicious cycle is eating a lot of fat and cutting out the refined carbs and sugar. A high-fat, low-carb diet leads to a faster metabolism and sustained weight loss.

Another experiment, conducted by Pascual-Leone when he was a researcher at the National Institutes of Health, provides even more remarkable evidence of the way our patterns of thought affect the anatomy of our brains. Pascual-Leone recruited people who had no experience playing a piano, and he taught them how to play a simple melody consisting of a short series of notes. He then split the participants into two groups. He had the members of one group practice the melody on a keyboard for two hours a day over the next five days. he had the members of the other group sit in front of a keyboard for the same amount of time but only imagine playing the song--without ever touching the keys. Using a technique called transcranial magnetic stimulation, or TMS, Pascual-Leone mapped the brain activity of all the participants before, during, and after the test. he found that the people who had only imagined playing the notes exhibited precisely the same changes in their brains as those who had actually pressed the keys. Their brains had changed in response to actions that took place purely in their imaginations--in response, that is, to their thoughts. Descartes may have been wrong about dualism, but he appears to have been correct in believing that our thoughts can exert a physical influence on, or at least cause a physical reaction in, our brains. We become, neurologically, what we think. (p33)

quite opposite to Descartes’s organ metaphor, our global neuronal workspace does not operate in an input-output manner, waiting to be stimulated before producing its outputs. On the contrary, even in full darkness, it ceaselessly broadcasts global patterns of neural activity, causing what William James called the “stream of consciousness”—an uninterrupted flow of loosely connected thoughts, primarily shaped by our current goals and only occasionally seeking information in the senses. René Descartes could not have imagined a machine of this sort, where intentions, thoughts, and plans continually pop up to shape our behavior. The outcome, I argue, is a “free-willing” machine that resolves Descartes’s challenge

Human desire tends to be insatiable. We are so anxious for pleasure that we can never get enough of it. We stimulate our sense organs until they become insensitive, so that if pleasure is to continue they must have stronger and stronger stimulants. In self-defense the body gets ill from the strain, but the brain wants to go on and on. The brain is in pursuit of happiness, and because the brain is much more concerned about the future than the present, it conceives happiness as the guarantee of an indefinitely long future of pleasures. Yet the brain also knows that it does not have an indefinitely long future, so that, to be happy, it must try to crowd all the pleasures of Paradise and eternity into the span of a few years.

This cycle puts the Intuitive-Sensitive in a difficult position. In order to avoid a system ‘shut-down’ they need to recover from the stimulation overload, yet they are faced with their biggest fear in another person – anger. They feel emotionally responsible for others and don’t want an argument, yet feel they need to ‘solve’ anger in another person. And if they can’t fix it, they will leave: they can only compromise themselves for so long before a survival mechanism directed towards self-preservation kicks in.

The essence of the adolescent brain changes that are the essence of healthy ways of living throughout the life span spell the word essence itself: ES: Emotional Spark—honoring these important internal sensations that are more intense during adolescence but serve to create meaning and vitality throughout our lives. SE: Social Engagement—the important connections we have with others that support our journeys through life with meaningful, mutually rewarding relationships. N: Novelty—how we seek out and create new experiences that engage us fully, stimulating our senses, emotions, thinking, and bodies in new and challenging ways. CE: Creative Explorations—the conceptual thinking, abstract reasoning, and expanded consciousness that create a gateway to seeing the world through new lenses.

Emotional interactions stimulate or inhibit the growth of nerve cells and circuits by complicated processes that involve the release of natural chemicals. To give a somewhat simplified example, when “happy” events are experienced by the infant, endorphins—“reward chemicals,” the brain’s natural opioids—are released. Endorphins encourage the growth and connections of nerve cells. Conversely, in animal studies, chronically high levels of stress hormones such as cortisol have been shown to cause important brain centres to shrink.

[...] A diet of constant, stimulating activity is the best prescription for our troubles. It keeps the brain in a state of constant change, flow, confirmation, and anticipation, thereby reducing the noise, fragility, self-doubt, and stagnation with which we all have to contend.

One of the reasons for learning about type is to recognize that we are constantly motivated, simply by the way we’ve established our neural networks, to shape reality along particular functional lines. Another is to recognize the possibilities for growth and change that exist within—and apart from—the framework we have created for ourselves. Even small changes in our usual way of doing things can make big differences in the way our brain is operating. We develop the ability to think in new ways, and this stimulates creative change in all areas of our lives.

A neurosurgeon once told me about operating on the brain of a young man with epilepsy. As is customary in this kind of operation, the patient was wide awake, under only local anesthesia, while the surgeon delicately explored his exposed cortex, makingsure that the parts tentatively to be removed were not absolutely vital by stimulating them electrically and asking the patient what he experienced. Some stimulations provoked visual flashes or hand-raisings, others a sort of buzzing sensation, but one spot produced a delighted response from the patient: "It's 'Outta Get Me' by Guns N' Roses. my favorite heavy metal band!" I asked the neurosurgeon If he had asked the patient to sing or hum along with the music, since it would be fascinating to learn how "high fidelity" the provoked memory was, would it be in exactly the same key and tempo as the record? Such a song (unliken"Silent Night") has one canonical version. so we could simply have superimposed a recording of the patients humming with the standard record and compared the results. Unfortunately, even though a tape recorder had been running during the operation, thesurgeon hadn't asked the patient to sing along. ''Why not?" I asked, and he replied: "I hate rock music!' Later in the conversation the neurosurgeon happened to remark that he was going to have to operate again on the same young man. and I expressed the hope that he would just check to see if he could restimulate the rock music, and this time ask the fellow to sing along. "I can't do it." replied the neurosurgeon. "since I cut out that part." "It was part of the epileptic focus?" I asked. "No,'' the surgeon replied, ''I already told you — I hate rock music.

It is noteworthy, however, that this areas also contains neurons which when stimulated can trigger female sexual posturing (Benson, 1988; Rose, 1990); i.e. the lordosis (or "doggie") position. These latter neurons are interconnected with the amygdala and ventromedial hypothalamus--nuclei

p 16 ...although our limbic system [eg. attention, fear, rage....] functions throughout our lifetime, it does not mature. As a result, when our emotional "buttons" are pushed, we retain the ability to react to incoming stimulation as though we were a two-year-old, even when we are adults.

People want to make this out to be a great American failing, but try this experiment: Take one hundred kids from that age group from any country, separate them on islands, give them the cocktail of constant affirmation and stimulation these kids were getting pumped through their brains, and one hundred times out of one hundred you have bloodshed. I guarantee it. Put yourself in the shoes of any of these kids, with their peers yelling “kill or be killed” in their ear, coaxing them, begging them to swing that sword or shoot that arrow or … or stab that other kid tied up and …

Peter Müller (1801–1858) had noticed something puzzling. If he shone light in the eye, put pressure on the eye, or electrically stimulated the nerves of the eye, all of these led to similar sensations of vision—that is, a sensation of light rather than of pressure or electricity. This suggested to him that we are not directly aware of the outside world, but instead only of the signals in the nervous system.8 In other words, when the nervous system tells you that something is “out there”—such as a light—that is what you will believe, irrespective of how the signals get there.

Caffeine has a calming effect on the ADHD brain. The theory is that the brain of people who suffer from the disorder has an overabundance of dopamine transporters, or re-uptake inhibitors. They carry away dopamine too fast, creating a shortage of it. In turn, that affects serotonin and norepinephrine. The combined effect is a reduced ability to focus, especially on tasks that the person doesn’t enjoy, a lesser ability to control impulsivity, and it even messes with the awareness of time. Caffeine stimulates dopamine production in the brain, temporarily filling up the gap created by the rapid

the body is equipped with what Cannon named the stress response, also known as the fight-or-flight response, a survival mechanism that gets flipped on when your brain perceives a threat. When this hormonal cascade is triggered by a thought or emotion in the mind, such as fear, the hypothalamic-pituitary-adrenocortical (HPA) axis activates, thereby stimulating the sympathetic nervous system to race into overdrive, pumping up the body’s cortisol and adrenaline levels. Over time, filling the body with these stress hormones can manifest as physical symptoms, predisposing the body to disease over time.

According to evolutionary theory, the brain is designed to pay special attention to what catches us off-guard, so we can be better prepared to meet the world next time. It even has a built-in novelty detector, a part that sends chemical signals to stimulate memory when new and different things happen.

It makes sense. It's all there. Everything that's beautiful or wise or significant has been written down at some time or other. How can anybody have the gall or the self-satisfaction to ignore all that? Who would want to? You read to feel alive, to bring things to life in yourself that you didn't know were there. All those folds and creases in your brain have some function, some potential, all the nerve endings are waiting to be stimulated. And it's all in the books. Everything. The whole fucking world is there if you know how to find it. Reading isn't an escape from life. It is life. It creates life.

Very well. Now, if you stimulate those damaged places in your brain again, you run the risk of opening up the old wounds. I mean, that if you get nerve-sensations of any kind producing the reactions which we call horror, fear, and sense of responsibility, they may go on to make disturbance right along the old channel, and produce in their turn physical changes which you will call by the names you were accustomed to associate with them—dread of German mines, responsibility for the lives of your men, strained attention and the inability to distinguish small sounds through the overpowering noise of guns.”   “I

Gordon Shepherd MD and PhD at Yale School of Medicine, said this: “The industry is geared to over-stimulating the senses of the consumer so that they eat more. The goal is to activate the parts of the brain that are susceptible to being conditioned to finding a product desirable and then wanting more of it.

Attentional amplification of sensory awareness in any sensory medium is achieved by top-down signals from prefrontal cortex that modulate activity of single neurons in sensory brain areas in the absence of any sensory stimulation and significantly increase baseline activity in the corresponding target region.

The only other consistently noted glandular change is in the thyroid. The work of several Soviet groups and one American team in the 1970s has clearly shown that radio and microwave frequencies, at power densities well below the American safety guideline of 10,000 microwatts, stimulate the thyroid gland and thus increase the basal metabolic rate. ELF fields at 50 hertz, on the other hand, have depressed thyroid activity in several experiments on rats. It isn't yet known whether this is a direct effect on the thyroid or whether, like the stress response, it's at least partly caused by alterations in brain function.

You can use cordyceps or baikal skullcap or rhodiola infusions to stimulate the production of root tissues in plants—including the root brain—sida acuta infusions to fight bacterial infections, isatis infusions to fight viral infections, or even plants high in brassinosteroids to help a plant’s immune function.

Do you know novelty can not only keep us engaged, but also serve as a source of motivation? When we are exposed to novelty, the dopamine pathway (the “pleasure/reward center” in our brain) is activated. Our brain is stimulated with a little rush of motivation, since it anticipates a potential reward and wants to explore further.

... They figured they would eat in California. Which would make them hungry, but Reacher didn't mind being hungry. he believed hunger kept him sharp. He believed is stimulated creativity in the brain. Another old evolutionary legacy. If you're hungry, you work out a smarter way to get the next woolly mammoth, today, not tomorrow.

For example, the euphoria brought on by DMT helped volunteers more unflinchingly look at their lives and conflicts. These ecstatic feelings may be, in part, related to the powerful DMT-induced surge of the morphinelike brain chemical beta-endorphin. DMT also stimulated a massive rise in the brain hormones vasopressin and prolactin. Scientists believe these compounds are important in feelings of bonding, attachment, and comfort with other members of the species. Perhaps the elevations in these brain chemicals made it easier for our volunteers to trust us, relax into the drug effects, and share powerfully personal issues in ways that previously were impossible.

So when nobody's watching, is the rainbow there? No, it is not. Your eyes are needed to complete the geometry. The triad of Sun, water droplets, and observer are all required for a rainbow. When no one is present, we can picture the situation as an infinity of potential rainbows, each slightly offset from the others with various color emphases (since bigger droplets produce more vivid rainbows but rob them of blue). Moreover, only when neurons in the retina and brain are stimulated by light's invisible magnetic and electrical pulses do they conjure the subjective experience of spectral colors. For both reasons, we are as necessary for rainbows as the Sun and the rain.

Bruce has wrestled with his moods, and a psyche genetically prone to extremes, for most of his adult life. Decades of psychotherapy helped reveal and cast light on some of his most primal traumas and conflicts, but his raw moods, and occasional descents into full-blown depression, never quite went away. "You go through periods of being good, then something stimulates it," he says. "The clock, some memory. You never know. The mind wants to link all your feelings to a cause. I'm feeling that because I'm doing this, or because that happened." Eventually Bruce realized that his worst moods had nothing to do with what was actually taking place in his life. Awful, stressful things could happen - conflicts, stress, disappointments, death - and he'd be unflappable. Then things would be peaceful and easy and he'd find himself on his knees. "You're going along fine, and then boom, it hits you. Things that just come from way down in the well. Completely noncasual, but it's part of your DNA, part of the way your body cycles." Bruce knows his particular brain chemistry will never leave him completely in the clear. "You manage it, you learn and evolve, but another recognition you gotta have is that these are the cards you were dealt," he says. "These things are never going to be out of your life. You gotta be constantly vigilant and realistic about these things.

How can two mutually exclusive behaviors—mating and fighting—be mediated by the same population of neurons? Anderson found that the difference hinges on the intensity of the stimulus applied. Weak sensory stimulation, such as foreplay, activates mating, whereas stronger stimulation, such as danger, activates aggression. In 1952 Meyer Schapiro paid

Though diagnosis is unquestionably critical in treatment considerations for many severe conditions with a biological substrate (for example, schizophrenia, bipolar disorders, major affective disorders, temporal lobe epilepsy, drug toxicity, organic or brain disease from toxins, degenerative causes, or infectious agents), diagnosis is often counterproductive in the everyday psychotherapy of less severely impaired patients. Why? For one thing, psychotherapy consists of a gradual unfolding process wherein the therapist attempts to know the patient as fully as possible. A diagnosis limits vision; it diminishes ability to relate to the other as a person. Once we make a diagnosis, we tend to selectively inattend to aspects of the patient that do not fit into that particular diagnosis, and correspondingly overattend to subtle features that appear to confirm an initial diagnosis. What’s more, a diagnosis may act as a self-fulfilling prophecy. Relating to a patient as a “borderline” or a “hysteric” may serve to stimulate and perpetuate those very traits. Indeed, there is a long history of iatrogenic influence on the shape of clinical entities, including the current controversy about multiple-personality disorder and repressed memories of sexual abuse. And keep in mind, too, the low reliability of the DSM personality disorder category (the very patients often engaging in longer-term psychotherapy).

There may be a genetic basis to how much dopamine each of our brains produces. The gene that codes for the production of dopamine is called DRD4 (dopamine receptor D4) and is located on the short arm of the eleventh chromosome. When dopamine is released by certain neurons in the brain it is picked up by other neurons that are receptive to its chemical structure, thereby establishing dopamine pathways that stimulate organisms to become more active and reward certain behaviors that then get repeated. If you knock out dopamine from either a rat or a human, for example, they will become catatonic. If you overstimulate the production of dopamine, you get frenetic behavior in rats and schizophrenic behavior in humans.

Every waking moment, our brains and bodies assimilate a myriad of sensory stimulation from the environment, as well as images, thoughts, emotions, body sensations, and movements from our internal state. In a millisecond, through operations so complex that they elude the full understanding of even the most brilliant minds, our brains compare this wealth of current data to memories of past experience. The most critical purpose of this comparison is to predict the next moment with sufficient accuracy so that we can make an adaptive physical action (Llinas, 2001). What we expect to happen in the very next instant determines the immediate action we make, whether it is reaching out to another person or for an object, such as a cup of tea.

no pain is localizable. The cutting of a finger andthe pain it brings seems localized, but it is simply a co-activation of pain, the emotional state, and general tactile stimulation. The unpleasantness of pain is an emotional state generated by the brain (Tolle et al. 1999; Treede et al. 1999), not an event that somehow resides at a particular body location (Greenfield 1995).

eat a little fat twenty-five minutes before your meal (70 calories or so of fat in the form of six walnut halves, twelve almonds, or twenty peanuts), you’ll stimulate a chemical that will both communicate with your brain and slow your stomach from emptying to keep you feeling full. (It takes about twenty-five minutes to kick in and takes about 65 calories of fat to stimulate.)

Doubting free will is not just a philosophical exercise. It has practical implications. If organisms indeed lack free will, it implies we could manipulate and even control their desires using drugs, genetic engineering or direct brain stimulation. If you want to see philosophy in action, pay a visit to a robo-rat laboratory. A robo-rat is a run-of-the-mill rat with a twist: scientists have implanted electrodes into the sensory and reward areas in the rat’s brain. This enables the scientists to manoeuvre the rat by remote control. After short training sessions, researchers have managed not only to make the rats turn left or right, but also to climb ladders, sniff around garbage piles, and do things that rats normally dislike, such as jumping from great heights.

Neural pathways become ingrained, automatic, if they operate only by habit. They are highly attuned to alterations, to novelty. New sights, sounds, languages, tastes, smells stimulate different synapses in the brain, different message routes, different webs of connection, increasing our neuroplasticity. Our brains have evolved to notice differences in our environment: it’s how we’re alerted to predators, to potential danger. To be sensitive to change, then, is to ensure survival. Professor Adam Galinsky, an American social psychologist who has studied the connection between creativity and international travel, says that ‘Foreign experiences increase both cognitive flexibility and depth and integrativeness of thought, the ability to make deep connections between disparate forms.

But Nozick did think long and hard about the relationship between hedonism and happiness. He once devised a thought experiment called the Experience Machine. Imagine that “superduper neuropsychologists” have figured out a way to stimulate a person’s brain in order to induce pleasurable experiences. It’s perfectly safe, no chance of a malfunction, and not harmful to your health. You would experience constant pleasure for the rest of your life. Would you do it? Would you plug into the Experience Machine? If not, argued Nozick, then you’ve just proved that there is more to life than pleasure. We want to achieve our happiness and not just experience it. Perhaps we even want to experience unhappiness, or at least leave open the possibility of unhappiness, in order to truly appreciate happiness.

In the Awakenings movie I found it very interesting that the most profound awakenings in the catatonic patients occurred in 1969, the year that the Aurora Borealis was seen from N.Y. to Louisiana. It seems the patients were getting environmental radiation stimulation in addition to their L-Dopa drug that year. L-Dopa plus radiation therapy may eventually be proven to be a very potent brain stimulant.

So let’s consider an alternative diet, say 1200 kcal consisting of 30% protein, 15% carbs (i.e., 180 kcal or 45 grams), and 55% fat. After a week or two of getting adapted (during which you may experience some of the fuel limitation symptoms discussed above), your serum ketones rise up in the range (1-2 millimolar) where they meet at least half of the brain’s fuel supply. Now if you go for that 5 mile run, almost all of your body’s muscle fuel comes from fat, leaving your dietary carb intake plus gluconeogenesis from protein to meet the minor fraction of your brain’s energy need not provided from ketones. And, oh yes, after your run while on the low carb diet, your ketone levels actually go up a bit (not dangerously so), further improving fuel flow to your brain. So what does this mean for the rest of us who are not compulsive runners? Well, this illustrates that the keto-adapted state allows your body more flexibility in meeting its critical organ energy needs than a ‘balanced’ but energy-restricted diet. And in particular, this also means that your brain is a “carbohydrate dependent organ” (as claimed by the USDA Dietary Guidelines Advisory Committee as noted in Chapter 3) ONLY when you are eating a high carbohydrate diet. When carbohydrate is restricted as in the example above, your body’s appropriate production of ketones frees the brain from this supposed state of ‘carbohydrate dependency’. And because exercise stimulates ketone production, your brain’s fuel supply is better supported during and after intense exercise when on a low carbohydrate diet than when your carbohydrate intake is high (see below).

Learning also increases dopamine firing in the brain. Female rats housed for three months in a diverse, novel, and stimulating environment show a proliferation of dopamine-rich synapses in the brain’s reward pathway compared to rats housed in standard laboratory cages. The brain changes that occur in response to a stimulating and novel environment are similar to those seen with high-dopamine (addictive) drugs.

Nietzsche wrote, “All truly great thoughts are conceived while walking,” and his observation is backed up by science; exercise-induced brain chemicals help people think clearly. In fact, just stepping outside clarifies thinking and boosts energy. Light deprivation is one reason that people feel tired, and even five minutes of daylight stimulates production of serotonin and dopamine, brain chemicals that improve mood.

Against bad diet.-- Phooey on the meals people cook these days, in restaurants as well as everywhere society's well-to-do class resides! Even when scholars of the highest reputation come together, they load their table according to the same custom as the banker loads his: following the principle of "much too much" and "ever such variety"-- from which it follows that the dishes are prepared with an eye to their effect instead of their efficacy, and stimulating drinks have to assist in driving out the heaviness from both stomach and brain. Phooey, what widespread dissoluteness and over-excitability as the inevitable consequence! Phooey, what dreams these people must have! Phooey, what arts and which books will be the desert of such dinners! And no matter what they do: pepper or contradiction or world-weariness will rule their actions!

Brain-imaging research is showing that glowing screens - like those of iPads - are as stimulating to the brain's pleasure centre and as able to increase levels of dopamine (the primary feel-good neurotransmitter) as much as sex does. This brain-orgasm effect is what makes screen so addictive for adults, but even more so for children with still-developing brains that just aren't equipped to handle that level of stimulation

I used to feel you in night. How the clouds touched the waves and the way you said alright. I still feel your hair, I still see you there. In corners of doorways, wandering to wander. It was never about you. It was never about I. It was about we. The stimulation of brains to pulse towards. Some things seem of importance to some while importance lies in the eyes of the beholder. Neither are wrong, but time is only enough for some.

Understand that bodies are shaped by culture from the very get-go,” explains Fausto-Sterling. “If you neglect a child at birth, their brain stops developing and they’re pretty messed up. If you highly stimulate a child, if they’re within a normal developmental range, they now develop all sorts of capacities you didn’t know they had or didn’t have the potential to develop. So the question always goes back to how development works.

Bristol-Meyers Squibb has reported success with monatomic ruthenium to correct cancer cells. Same with platinum and iridium, according to Platinum Metals Review. These atoms actually make the DNA strand correct itself, rebuilding without drugs or radiation. Iridium has been shown to stimulate the pineal gland and appears to fire up ‘junk DNA,’ leading to the possibility of increased longevity and reopening aging pathways in the brain.

Though we feel that we can choose what we do, our understanding of the molecular basis of biology shows that biological processes are governed by the laws of physics and chemistry and therefore are as determined as the orbits of the planets. Recent experiments in neuroscience support the view that it is our physical brain, following the known laws of science, that determines our actions, and not some agency that exists outside those laws. For example, a study of patients undergoing awake brain surgery found that by electrically stimulating the appropriate regions of the brain, one could create in the patient the desire to move the hand, arm, or foot, or to move the lips and talk. It is hard to imagine how free will can operate if our behavior is determined by physical law, so it seems that we are no more than biological machines and that free will is just an illusion.

When looking at the brains of injured patients, Paul Broca (1824–1880) discovered that the left temporal cortex was responsible for speech. When Penfield electrically stimulated the brains of patients undergoing surgery, he confirmed the function of speech was in the left temporal lobe. We know that the motor cortex lies at the front of the brain in a strip along the midline. Sensory processing from the skin lies just to the back of the

Being around other people and developing close relationships feels good for a reason, and that reason is dopamine. Thus it’s not surprising that dopamine and oxytocin interact with each other. Dopamine neurons connect to the part of the hypothalamus where oxytocin is produced, and oxytocin stimulates the area of the brain stem where dopamine is produced. In addition, the dopamine-rich nucleus accumbens receives input from oxytocin neurons.

In addition to localized neural networks, hallucinogenic drugs have been documented to trigger such preternatural experiences, such as the sense of floating and flying stimulated by atropine and other belladonna alkaloids. These can be found in mandrake and jimsonweed and were used by European witches and American Indian shamans, probably for this very purpose.32 Dissociative anesthetics such as the ketamines are also known to induce out-of-body experiences. Ingestion of methylenedioxyamphetamine (MDA) may bring back long-forgotten memories and produce the feeling of age regression, while dimethyltryptamine (DMT)—also known as “the spirit molecule”—causes the dissociation of the mind from the body and is the hallucinogenic substance in ayahuasca, a drug taken by South American shamans. People who have taken DMT report “I no longer have a body,” and “I am falling,” “flying,” or “lifting up.

You’ve probably also noted the impacts of virtual distraction on your own and others’ behaviors: memory loss, inability to concentrate, being asked to repeat what you just said, miscommunication the norm, getting lost online and wasting time you don’t have, withdrawing from the real world. The list of what’s being lost is a description of our best human capacities—memory, meaning, relating, thinking, learning, caring. There is no denying the damage that’s been done to humans as technology took over—our own Progress Trap. The impact on children’s behavior is of greatest concern for its present and future implications. Dr. Nicolas Kardaras, a highly skilled physician in rehabilitation, is author of Glow Kids: How Screen Addiction Is Hijacking Our Kids—and How to Break the Trance. He describes our children’s behavior in ways that I notice in my younger grandchildren: “We see the aggressive temper tantrums when the devices are taken away and the wandering attention spans when children are not perpetually stimulated by their hyper-arousing devices. Worse, we see children who become bored, apathetic, uninteresting and uninterested when not plugged in.”17 These very disturbing behaviors are not just emotional childish reactions. Our children are behaving as addicts deprived of their drug. Brain imaging studies show that technology stimulates brains just like cocaine does.

Many of those skilled in technological warfare believe that physical training and discipline are unnecessary. With turbolasers, hyperdrives, armor plating and the mental resources to direct them, muscular strength and agility are thought to be merely conceits. They are wrong. The mind and body are linked together in a meshwork of oxygen, nutrients, hormones and neuron health. Physical exercise drives that meshwork, stimulating the brain and freeing one's intellect.

Instagram and Facebook, she’d found out, literally rewired your brain. Likes and comments on a user’s post were found to release bursts of dopamine, which made the user happy. That made sense; everyone enjoyed getting likes on a Facebook post. But this essentially turned the phone into a personal dopamine stimulator. Brain scans showed that in cases of people who were addicted to social media, the brain rewired itself, making them desire more likes, or retweets, or smiling emojis.

At the same time, such technology—from the television to the computer and phone—can put pressure on the brain by presenting it with more information, and of a type of information, that makes it hard for us to keep up. That is particularly true of interactive electronics, delivering highly relevant, stimulating social content, and with increasing speed. The onslaught taxes our ability to attend, to pay attention, arguably among the most important, powerful, and uniquely human of our gifts.

brain researcher Arash Javanbakht notes . . . In a world where we are simultaneously bombarded with a great deal of stimulation, we learn to focus our attention on important stimuli, while filtering out (gating) less relevant stimuli. Sensory gating (SG) is a way of habituation to repetitious and unimportant stimuli for the brain to reserve its limited resources to focus on important stimuli that need processing.3 It helps us focus on what we have determined, through experience, schooling, and cultural habituation, to be important.

Most people are shocked to hear that a video game can actually be more potent than morphine. While this is a phenomenal advance in pain-management medicine and treatment of burn victims, it begs the question: just what effect is this digital drug—which is more powerful than morphine—having on the brains and nervous systems of seven-year-olds—or fourteen year-olds—who are ingesting very similar digital drugs via their glowing screens? And, further, if stimulating screens are indeed more powerful than morphine, can they be just as addicting?

are biased toward studying individual organisms. It is often difficult for scientists to grasp the idea that individual brains do not exist in nature. As much as one may adhere to the notion of the isolated self, humans have evolved as social creatures and are constantly regulating one another’s biology. Without mutually stimulating interactions, people (and neurons for that matter) wither and die. In neurons this process is called apoptosis (programmed cell death); in humans it is called failure to thrive, depression, or dying of a broken heart.

Again as during fetal development, synapses that underlie cognitive and other abilities stick around if they’re used but wither if they’re not. The systematic elimination of unused synapses, and thus unused circuits, presumably results in greater efficiency for the neural networks that are stimulated—the networks that support, in other words, behaviors in which the adolescent is actively engaged. Just as early childhood seems to be a time of exquisite sensitivity to the environment (remember the babies who dedicate auditory circuits only to the sounds of their native language, eliminating those for phonemes that they do not hear), so may adolescence. The teen years are, then, a second chance to consolidate circuits that are used and prune back those that are not—to hard-wire an ability to hit a curve ball, juggle numbers mentally, or turn musical notation into finger movements almost unconsciously. Says Giedd, “Teens have the power to determine their own brain development, to determine which connections survive and which don’t, [by] whether they do art, or music, or sports, or videogames.

Hermione. “I confiscated that too. None of these things actually works you know —” “Dragon claw does work!” said Ron. “It’s supposed to be incredible, really gives your brain a boost, you come over all cunning for a few hours — Hermione, let me have a pinch, go on, it can’t hurt —” “This stuff can,” said Hermione grimly. “I’ve had a look at it, and it’s actually dried doxy droppings.” This information took the edge off Harry and Ron’s desire for brain stimulants. They received their examination schedules and details of the procedure for O.W.L.s during their next

The beauty of exercise is that it attacks the problem from both directions at the same time. It gets us moving, naturally, which stimulates the brain stem and gives us more energy, passion, interest, and motivation. We feel more vigorous. From above, in the prefrontal cortex, exercise shifts our self-concept by adjusting all the chemicals I’ve mentioned, including serotonin, dopamine, norepinephrine, BDNF, VEGF, and so on. And unlike many antidepressants, exercise doesn’t selectively influence anything—it adjusts the chemistry of the entire brain to restore normal signaling.

Subject: SELF WORTH (Very Deep!!!) In a brief conversation, a man asked a woman he was pursuing the question: 'What kind of man are you looking for?' She sat quietly for a moment before looking him in the eye & asking, 'Do you really want to know?' Reluctantly, he said, 'Yes. She began to expound, 'As a woman in this day & age, I am in a position to ask a man what can you do for me that I can't do for myself? I pay my own bills. I take care of my household without the help of any man... or woman for that matter. I am in the position to ask, 'What can you bring to the table?' The man looked at her. Clearly he thought that she was referring to money. She quickly corrected his thought & stated, 'I am not referring to money. I need something more. I need a man who is striving for excellence in every aspect of life. He sat back in his chair, folded his arms, & asked her to explain. She said, 'I need someone who is striving for excellence mentally because I need conversation & mental stimulation. I don't need a simple-minded man. I need someone who is striving for excellence spiritually because I don't need to be unequally yoked...believers mixed with unbelievers is a recipe for disaster. I need a man who is striving for excellence financially because I don't need a financial burden. I need someone who is sensitive enough to understand what I go through as a woman, but strong enough to keep me grounded. I need someone who has integrity in dealing with relationships. Lies and game-playing are not my idea of a strong man. I need a man who is family-oriented. One who can be the leader, priest and provider to the lives entrusted to him by God. I need someone whom I can respect. In order to be submissive, I must respect him. I cannot be submissive to a man who isn't taking care of his business. I have no problem being submissive...he just has to be worthy. And by the way, I am not looking for him...He will find me. He will recognize himself in me. Hey may not be able to explain the connection, but he will always be drawn to me. God made woman to be a help-mate for man. I can't help a man if he can't help himself. When she finished her spill, she looked at him. He sat there with a puzzled look on his face. He said, 'You are asking a lot. She replied, "I'm worth a lot". Send this to every woman who's worth a lot.... and every man who has the brains to understand!!

ASPARTAME AND MSG: EXCITOTOXINS Aspartame is, in fact, an excitotoxin, one of a group of substances, usually acidic amino acids, that in high amounts react with specialized receptors in the brain, causing destruction of certain types of neurons. A growing number of neurosurgeons and neurologists are convinced that excitotoxins play a critical role in the development of several neurological disorders, including migraines, seizures, learning disorders in children, and neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and amyotrophic lateral sclerosis (ALS).1 Glutamate and aspartate are two powerful amino acids that act as neurotransmitters in the brain in very small concentrations, but they are also commonly available in food additives. Glutamate is in MSG, a flavor enhancer, and in hydrolyzed vegetable protein, found in hundreds of processed foods. Aspartate is one of three components of aspartame (NutraSweet, Equal), a sugar substitute. In higher concentrations as food additives, these chemicals constantly stimulate brain cells and can cause them to undergo a process of cell death known as excitotoxicity—the cells are excited to death.

After all, across the population there are slight differences in brain function, and sometimes these translate directly into different ways of experiencing the world. And each individual believes his way is reality. To get a sense of this, imagine a world of magenta Tuesdays, tastes that have shapes, and wavy green symphonies. One in a hundred otherwise normal people experience the world this way, because of a condition called synesthesia (meaning “joined sensation”).5 In synesthetes, stimulation of a sense triggers an anomalous sensory experience: one may hear colors, taste shapes, or systematically experience other sensory blendings. For example, a voice or music may not only be heard but also seen, tasted, or felt as a touch. Synesthesia is a fusion of different sensory perceptions: the feel of sandpaper might evoke an F-sharp, the taste of chicken might be accompanied by a feeling of pinpoints on the fingertips, or a symphony might be experienced in blues and golds. Synesthetes are so accustomed to the effects that they are surprised to find that others do not share their experiences. These synesthetic experiences are not abnormal in any pathological sense; they are simply unusual in a statistical sense.

Perhaps the most exasperating cliche is about children being forced to memorize, not think. But memorization is not an abomination in itself, though the mnemic pressure on our species has dropped. Memorization is, de facto, exercise for the mind. Neuroscience shows an active hippocampus stimulates cerebral activity. We have often observed how the most profound and creative pupils are those who know the most things, though their usefulness is not always apparent. No question is more insinuating stupid than 'What good will it do to me?' In certain teaching contexts, it is not wrong to ask pupils to memorize. While it is not the only goal the idea that memorizing is useless since information is available online is also wrong and falsely self-obvious. It denotes a misunderstanding of how our mind works. Our brains are not computers, our memory can't be replaced by external HDDs. Each piece of info we memorize is integrated, albeit minimally, as living memory is active, while digital memory is passive. Strange as some may find it, memorizing can stimulate thinking as few other things can. What impairs thinking is the lack of the habit to reflect, the custom of stopping our mind's flow to go back to what we've learned.

Walking into a bookshop is a depressing thing. It’s not the pretentious twats, browsing books as part of their desirable lifestyle. It’s not the scrubby members of staff serving at the counter: the pseudo-hippies and fucking misfits. It’s not the stink of coffee wafting out from somewhere in the building, a concession to the cult of the coffee bean. No, it’s the books. I could ignore the other shit, decide that maybe it didn’t matter too much, that when consumerism meets culture, the result is always going to attract wankers and everything that goes with them. But the books, no, they’re what make your stomach sink and that feeling of dark syrup on the brain descend. Look around you, look at the shelves upon shelves of books – for years, the vessels of all knowledge. We’re part of the new world now, but books persist. Cheap biographies, pulp fiction; glossy covers hiding inadequate sentiments. Walk in and you’re surrounded by this shit – to every side a reminder that we don’t want stimulation anymore, we want sedation. Fight your way through the celebrity memoirs, pornographic cook books, and cheap thrills that satisfy most and you get to the second wave of vomit-inducing product: offerings for the inspired and arty. Matte poetry books, classics, the finest culture can provide packaged and wedged into trendy coverings, kidding you that you’re buying a fashion accessory, not a book. But hey, if you can stomach a trip further into the shop, you hit on the meatier stuff – history, science, economics – provided they can stick ‘pop.’ in front of it, they’ll stock it. Pop. psychology, pop. art, pop. life. It’s the new world – we don’t want serious anymore, we want nuggets of almost-useful information. Books are the past, they’re on the out. Information is digital now; bookshops, they’re somewhere between gallery and museum.

I have already told you about experiments where babies are taught the meaning of a new word, such as “wog.” If the infants can follow the speaker’s gaze toward the so-called wog, they have no trouble learning this word in just a few trials—but if wog is repeatedly emitted by a loudspeaker, in direct relation to the same object, no learning occurs. The same goes for learning phonetic categories: a nine-month-old American child who interacts with a Chinese nanny for only a few weeks acquires Chinese phonemes—but if he receives exactly the same amount of linguistic stimulation from a very high-quality video, no learning occurs.

The Seeking system was discovered when the psychologists James Olds and Peter Milner implanted an electrode into the middle of a rat brain, hooked it up to a lever in a Skinner box, and found that the rat would press the lever to stimulate its own brain until it dropped of exhaustion.53 Originally they thought they had found the pleasure center in the brain, but neuroscientists today believe that the system underlies wanting or craving rather than actual pleasure. (The major realization of adulthood, that you should be careful about what you want because when you get it you may not enjoy it, has a basis in the anatomy of the brain.)

The ability to draw a connection between two things that had previously appeared to be unrelated is an important part of creativity, and it appears that it can be enhanced by electrical stimulation. Compared to participants who were given fake tDCS, those who got electricity created more unusual analogies—that is, analogies between things that seemed very unlike one another. Nevertheless, these highly creative analogies were just as accurate as the more obvious ones created by the participants whose devices were secretly turned off. Dopaminergic drugs can do the same thing. Although some patients who take dopaminergic drugs for Parkinson’s disease develop devastating compulsions, others experience enhanced creativity. One patient who came from a family of poets had never done any creative writing. After starting dopamine-boosting drugs for his Parkinson’s disease, he wrote a poem that won the annual contest of the International Association of Poets. Painters treated with Parkinson’s medication often increase their use of vivid color. One patient who developed a new style after being treated said, “The new style is less precise but more vibrant. I have a need to express myself more. I just let myself go.” Just like Winnie-the-Pooh: “It is the best way to write poetry, letting things come.

There's a psychologist called Mary & Diamond who at Brooklyn in California, in the 80s studied rats. And they took rats at different ages. Newborns, some of whom they deliberately brain damaged, adult, middle-aged, elderly rats. And they exposed these rats to different levels of environmental stimulation, better food, more playmates, toys to play with and so on. They found out a couple of months later that the rats, at any age, including the brain-damaged rats, who had the better stimulation, they were smarter. But in the autopsy then they also found that in the front part of their brain they had larger nerve-cells with more connections with other nerve-cells and richer blood supply. In other words that environmental stimulation actually caused a change in the state of the brain, even in the older rats. And that's called neuroplasticity. The capacity of the brain to develop new circuits. So whether it comes to ADHD, addiction, depression or other childhood disorders or any other issue with adults as well, if we recognize them not as ingrained, genetically-determined diseases, but as problems of development, then the question becomes very different. Then the question becomes not just "how do we treat the symptoms?" (and addiction itself is a symptom, depression is a symptom), but "how do we help people develop out of these conditions?" In other words, it is not a medical question, purely, but a developmental question. And development always requires the right environment. Now, if you're a gardener you know that. If you are growing plants in your backyard and you want them to grow into healthy, functioning beings, botanical beings, you want to provide them with the right nurturing, the right nutrition, minerals, water, sunlight and so on. So the real question is how do we provide the conditions for further development for people whose development was impaired in the first place? Now we know how to do that. We are just not doing it.

higher states of arousal come with decreased abilities to self-quiet. Elevated states of arousal are further coupled with a reduced ability to self-stimulate and self-entertain. This includes reduced abilities to observe, integrate information, and to be creative. In essence, we have less ability to sustain focus on the normal, the baseline, including states of observation, contemplation, and transitions from which ideas spark — what many under the age of twenty now consider a void, proclaiming boredom. We now feel agitated when not externally stimulated; we need to be occupied, entertained. We also have greater troubles quieting, including reaching states of repose, satisfaction, and restorative sleep.

He postulated that many neurons can combine into a coalition, becoming a single processing unit. The connection patterns of these units, which can change, make up the algorithms (which can also change with the changing connection patterns) that determine the brain’s response to a stimulus. From this idea came the mantra “Cells that fire together wire together.” According to this theory, learning has a biological basis in the “wiring” patterns of neurons. Hebb noted that the brain is active all the time, not just when stimulated; inputs from the outside can only modify that ongoing activity. Hebb’s proposal made sense to those designing artificial neural networks, and it was put to use in computer programs.

One of the most remarkable properties of our brain is its capacity to change and adapt to our individual world. Neurons and neural networks actually make physical changes when stimulated; this is called neuroplasticity. The way they become stimulated is through our particular experiences: The brain changes in a “use dependent” way. The neural networks involved in piano playing, for example, will make changes when activated by a child practicing her piano. These experience-dependent changes translate into better piano playing. This aspect of neuroplasticity—repetition leads to change—is well known and is why practice in sports, arts, and academics can lead to improvement. A key principle of neuroplasticity is specificity. In order to change any part of the brain, that specific part of the brain must be activated. If you want to learn to play the piano, you can’t simply read about piano playing, or watch and listen to YouTube clips of other people playing piano. You must put your hands on the keys and play; you have to stimulate the parts of the brain involved in piano playing in order to change them. This principle of “specificity” applies to all brain-mediated functions, including the capacity to love. If you have never been loved, the neural networks that allow humans to love will be undeveloped, as in Gloria’s case. The good news is that with use, with practice, these capabilities can emerge. Given love, the unloved can become loving.

Original Statement by Hunger Strikers to Psychiatric Association, National Alliance for the Mentally Ill and the U.S. Office of the Surgeon General 1. A Hunger Strike to Challenge International Domination by Biopsychiatry. This fast is about human rights in mental health. The psychiatric pharmaceutical complex is heedless of its oath to “first do no harm.” Psychiatrists are able with impunity to: Incarcerate citizens who have committed crimes against neither persons nor property. Impose diagnostic labels on people that stigmatize and defame them. Induce proven neurological damage by force and coercion with powerful psychotropic drugs. Stimulate violence and suicide with drugs promoted as able to control these activities. Destroy brain cells and memories with an increasing use of electroshock (also known as electro-convulsive therapy). Employ restraint and solitary confinement—which frequently cause severe emotional trauma, humiliation, physical harm, and even death—in preference to patience and understanding. Humiliate individuals already damaged by traumatizing assaults to their self-esteem. These human rights violations and crimes against human decency must end. While the history of psychiatry offers little hope that change will arrive quickly, initial steps can and must be taken. At the very least, the public has the right to know IMMEDIATELY the evidence upon which psychiatry bases its spurious claims and treatments, and upon which it has gained and betrayed the trust and confidence of the courts, the media, and the public.21

The concept of “brain plasticity” refers to the ongoing capacity of the brain and the nervous system to change itself. Everything that we do, think, feel, and experience changes our brain. A stroke or a traumatic brain injury can affect brain plasticity, and plasticity may also be associated with such developmental disorders as autism. Increased brain plasticity may also potentially endow a person with unanticipated new abilities, as John appears to have experienced in this book. TMS, or transcranial magnetic stimulation, the intervention that John undergoes, provides a unique opportunity for us to learn about the mechanisms of plasticity, and to identify alterations in the brain’s networks that may be responsible for a patient’s problematic symptoms, and also for recovery.

She zips out the Congressional Record from February 24, 1972, and reads the testimony of Dr. Jose Delgado from Yale University, who was arguing against the proposed discontinuation of research into psychosurgery:            We need a program of psychosurgery for political control of our society. The purpose is physical control of the mind. Everyone who deviates from the given norm can be surgically mutilated. The individual may think that the most important reality is his own existence, but this is only his personal view. This lacks historical perspective. Man does not have the right to develop his own mind. This kind of liberal orientation has great appeal. We must electrically control the brain. Someday armies and generals will be controlled by electric stimulation of the brain.

Practical affairs task the human brain throughout the day. At night, the mind takes a deserved hiatus to consider the impossible and the absurd. In the carnage of our nighttime sleep tussles, the colored liqueurs of the true, the possible, fantasy, and the mythic beliefs become intermixed. Eyelets of the commonsensical and the imaginative are incorporated, and a new realism emerges out of our distilled perception of the veridical derived from the phenomenal realm of sensory reality and the philosophic world of ideals contained in the noumenal realm. The resultant psychobiologic vision immerses us in bouts of intoxicating inspiration and artistic stimulation and leaves us rickety boned and weakened after enduring a dreaded hangover of perpetual doubt laced with vagueness and insecurity.

The firm’s fourth partner, Jeff Nussbaum, had carved out a niche writing jokes for public figures. It was he who taught me about the delicate balance all public-sector humorists hope to strike. Writing something funny for a politician, I learned, is like designing something stunning for Marlon Brando past his prime. The qualifier is everything. At first I didn’t understand this. In June, President Obama’s speechwriters asked Jeff to pitch jokes for an upcoming appearance at the Radio and Television Correspondents’ Dinner. I sent him a few ideas, including one about the president and First Lady’s recent trip to see a Broadway show: “My critics are upset it cost taxpayer dollars to fly me and Michelle to New York for date night. But let me be clear. That wasn’t spending. It was stimulus.” Unsurprisingly, my line about stimulating America’s first couple didn’t make it into the script. But others did. The morning after the speech, I watched on YouTube as President Obama turned to NBC reporter Chuck Todd. “Chuck embodies the best of both worlds: he has the rapid-fire style of a television correspondent, and the facial hair of a radio correspondent.” That was my joke! I grabbed the scroll bar and watched again. The line wasn’t genius. The applause was largely polite. Still, I was dumbfounded. A thought entered my brain, and then, just a few days later, exited the mouth of the president of the United States. This was magic. Still, even then, I had no illusions of becoming a presidential speechwriter. When friends asked if I hoped to work in the White House, I told them Obama had more than enough writers already. I meant it.

The psychologist Geoffrey Miller, when pondering why we haven’t come across any alien species as yet, decided that they were probably all addicted to video games and are thus brought to an extreme state of apathy—the exploratory opposite of the heroes in Star Trek who spend all their time seeking out “new life and new civilizations.” The aliens “forget to send radio signals or colonize space,” he wrote in Seed magazine, because they’re too busy with runaway consumerism and virtual-reality narcissim. They don’t need Sentinels to enslave them in a Matrix; they do it to themselves, just as we are doing today. . . . They become like a self-stimulating rat, pressing a bar to deliver electricity to its brain’s ventral tegmental area, which stimulates its nucleus accumbens to release dopamine, which feels . . . ever so good.

listening to stories while looking at pictures stimulates children’s deep brain networks, fostering their optimal cognitive development. Further, the companionable experience of shared reading cultivates empathy, dramatically accelerates young children’s language acquisition, and vaults them ahead of their peers when they get to school. The rewards of early reading are astonishingly meaningful: toddlers who have lots of stories read to them turn into children who are more likely to enjoy strong relationships, sharper focus, and greater emotional resilience and self-mastery. The evidence has become so overwhelming that social scientists now consider read-aloud time one of the most important indicators of a child’s prospects in life. It would be a mistake, though, to relegate reading aloud solely to the realm of childhood.

Remember, never give up on love. It is easier to give up in search of a better prize, because the brain always keeps craving for new stimulants, but this way you only keep on searching, never to find peace in love. Let me tell you a story. There was a student who asked his teacher, what is love. The teacher said go into the field and bring me the most beautiful flower. The student returned with no flower at hand and said, I found the most beautiful flower in the field but I didn't pick it up for I might find a better one, but when I returned to the place, it was gone. We always look for the best in life. When we finally see it, we take it for granted and after some time start expecting a better one, not knowing that it's the best. Seek for your love, and once you have it never ever give up on it, no matter the situations.

Philosophy is the creative art of cunning 'Demons' -- it is going to fill human brain and heart with doubt in everything. Even the fact that you do really exist in reality, which seems so obvious and undeniable, becomes a matter of doubt. How can you definitely insist that you are not only bodies brain under the stimulation in such a way that some external being(s) -- supernatural or natural -- feed your brain with the illusory ideas that you are real, and perhaps you are sitting in front of the computer, and reading what is written there. And there is no definite fact that this is not the case, but instead, it is very, very difficult to resist the temptation of philosophical thinking in that direction -- therefore, sooner or later you are going to be involved in such kind of 'demonic' activity, if you are really determined to penetrate deep into mind-blowing questions of philosophy.

Such networks of neurons are built following the principle that “cells that fire together, wire together” (Hebb’s rule). In short, neurons that are frequently active at the same time tend to become associated and end up connecting with one another. This principle has major implications for brain fitness. First, the more a network of neurons is activated (i.e., the more often the neurons fire together), the stronger the connections become. If a network supporting a brain function is repeatedly stimulated through practice and training, it will become stronger, contributing to the optimization of that brain function. Second, by contrast, the less a network of neurons is activated the weaker the connections become, and weak connections end up dying. This accounts for the popular idea “use it or lose it” – brain functions that are not stimulated end up losing their efficiency since the neural networks supporting them weaken or dissipate.

These genetic malfunctions are unlikely to produce schizophrenia in an individual unless they are stimulated by environmental conditions. By far the most causative environmental factor is stress, especially during gestation in the womb, early childhood, and adolescence—stages in which the brain is continually reshaping itself, and thus vulnerable to disruption. Stress can take the form of a person's enduring sustained anger, fear, or anxiety, or a combination of these. Stress works its damage by prompting an oversupply of cortisol, the normally life sustaining “stress hormone” that converts high energy glycogen to glucose in liver and in muscle tissue. Yet when it is called upon to contain a rush of glycogen, cortisol can transform itself into “Public Enemy Number One,” as one health advocate put it. The steroid hormone swells to flood levels and triggers weight gain, high blood pressure, heart disease, damage to the immune system, and an overflow of cholesterol. Stress is likely a trigger for schizophrenia.

The areas of the cortex responsible for attention and self-regulation develop in response to the emotional interaction with the person whom we may call the mothering figure. Usually this is the birth mother, but it may be another person, male or female, depending on circumstances. The right hemisphere of the mother’s brain, the side where our unconscious emotions reside, programs the infant’s right hemisphere. In the early months, the most important communications between mother and infant are unconscious ones. Incapable of deciphering the meaning of words, the infant receives messages that are purely emotional. They are conveyed by the mother’s gaze, her tone of voice and her body language, all of which reflect her unconscious internal emotional environment. Anything that threatens the mother’s emotional security may disrupt the developing electrical wiring and chemical supplies of the infant brain’s emotion-regulating and attention-allocating systems. Within minutes following birth, the mother’s odors stimulate the branching of millions of nerve cells in the newborn’s brain. A six-day-old infant can already distinguish the scent of his mother from that of other women. Later on, visual inputs associated with emotions gradually take over as the major influences. By two to seven weeks, the infant will orient toward the mother’s face in preference to a stranger‘s — and also in preference to the father’s, unless the father is the mothering adult. At seventeen weeks, the infant’s gaze follows the mother’s eyes more closely than her mouth movements, thus fixating on what has been called “the visible portion of the mother’s central nervous system.” The infant’s right brain reads the mother’s right brain during intense eye-to-eye mutual gaze interactions. As an article in Scientific American expressed it, “Embryologically and anatomically the eye is an extension of the brain; it is almost as if a portion of the brain were in plain sight.” The eyes communicate eloquently the mother’s unconscious emotional states.

For example, when I observe something unusual in an experiment, it reverberates in my brain for a long while. Many circuits, especially the giant recurrent network of the hippocampus, can generate large numbers of neuronal trajectories without any signals from outside the brain. Even cultured brain tissue in a dish can induce a variety of spontaneous events. That is what neuronal circuits do.38 They do not just sit and wait to be stimulated. Based on these examples, now we may consider the possibility that learning is not an outside-in superimposition process where new neuronal sequences are built up with each novel experience. Instead, learning may be an inside-out matching process: when a spontaneously occurring neuronal trajectory, drawn from the available huge repertoire of trajectories, coincides with a useful action, that trajectory acquires meaning to the brain. The richer the experience, the higher the fraction of the meaningful trajectories, but there is always a large reservoir of available patterns.

I define responsibility (response-ability) as the ability to choose how we respond to stimulation coming in through our sensory systems at any moment in time. Although there are certain limbic system (emotional) programs that can be triggered automatically, it takes less than 90 seconds for one of these programs to be triggered, surge through our body, and then be completely flushed out of our blood stream. My anger response, for example, is a programmed response that can be set off automatically. Once triggered, the chemical released by my brain surges through my body and I have a physiological experi-ence. Within 90 seconds from the initial trigger, the chemical component of my anger has completely dissipated from my blood and my automatic response is over. If, however, I remain angry after those 90 seconds have passed, then it is because I have chosen to let that circuit continue to run. Moment by moment, I make the choice to either hook into my neurocircuitry or move back into the present moment, allowing that reaction to melt away as fleeting physiology.

Blaine: THE HAND-SCAN SPECTRUM MAGNIFIER IS A DIAGNOSTIC TOOL ALSO CAPABLE OF ADMINISTERING MINOR FIRST AID, SUCH AS I HAVE PERFORMED ON YOU. IT IS ALSO A NUTRIENT DELIVERY SYSTEM, A BRAIN-PATTERN RECORDING DEVICE, A STRESS-ANALYZER, AND AN EMOTION-ENHANCER WHICH CAN NATURALLY STIMULATE THE PRODUCTION OF ENDORPHINS. HAND-SCAN IS ALSO CAPABLE OF CREATING VERY BELIEVABLE ILLUSIONS AND HALLUCINATIONS. WOULD YOU CARE TO HAVE YOUR FIRST SEXUAL EXPERIENCE WITH A NOTED SEX-GODDESS FROM YOUR LEVEL OF THE TOWER, JAKE OF NEW YORK? PERHAPS MARILYN MONROE, RAQUEL WELCH, OR EDITH BUNKER? Jake: (laughter; guessing that laughing at Blaine might be risky, but this time he cannot help it) There IS no Edith Bunker. She's just a character on a TV show. The actress's name is, um, Jean Stapleton. Also, she looks like Mrs. Shaw. She's our housekeeper. Nice, but not--you know--a babe. Blaine: (silence) I CRY YOUR PARDON, JAKE OF NEW YORK. I ALSO WITHDRAW MY OFFER OF A SEXUAL EXPERIENCE. Jake: (sounding suitably humble hopefully) That's okay, Blaine. I think I'm still a little young for that, anyway.

neurophysiologist Olaf Blanke, who came across the phenomenon unexpectedly. He had triggered it with electrical stimulation to the temporal parietal cortex of a patient’s brain while trying to locate the focus of a seizure.8 He has also studied a bevy of patients who complain of an FoP. He found that lesions in the frontoparietal area are specifically associated with the phenomenon and are on the opposite side of the body from the presence.9 This location suggested to him that disturbances in sensorimotor processing and multisensory integration may be responsible. While we are conscious of our location in space, we are unaware of the multitude of processes (vision, sound, touch, proprioception, motor movement, etc.) that, when normally integrated, properly locate us there. If there is a disorder in the processing, errors can occur and our brains can misinterpret our location. Blanke and his colleagues have found that one such error manifests itself as an FoP. Recently, they cleverly induced the FoP in healthy subjects by disordering their sensory processing with the help of a robotic arm.10

I believe that social media, and the internet as a whole, have negatively impacted our ability to both think long-term and to focus deeply on the task in front of us. It is no surprise, therefore, that Apple CEO, Steve Jobs, prohibited his children from using phones or tablets—even though his business was to sell millions of them to his customers! The billionaire investor and former senior executive at Facebook, Chamath Palihapitiya, argues that we must rewire our brain to focus on the long term, which starts by removing social media apps from our phones. In his words, such apps, “wire your brain for super-fast feedback.” By receiving constant feedback, whether through likes, comments, or immediate replies to our messages, we condition ourselves to expect fast results with everything we do. And this feeling is certainly reinforced through ads for schemes to help us “get rich quick”, and through cognitive biases (i.e., we only hear about the richest and most successful YouTubers, not about the ones who fail). As we demand more and more stimulation, our focus is increasingly geared toward the short term and our vision of reality becomes distorted. This leads us to adopt inaccurate mental models such as: Success should come quickly and easily, or I don’t need to work hard to lose weight or make money. Ultimately, this erroneous concept distorts our vision of reality and our perception of time. We can feel jealous of people who seem to have achieved overnight success. We can even resent popular YouTubers. Even worse, we feel inadequate. It can lead us to think we are just not good enough, smart enough, or disciplined enough. Therefore, we feel the need to compensate by hustling harder. We have to hurry before we miss the opportunity. We have to find the secret that will help us become successful. And, in this frenetic race, we forget one of the most important values of all: patience. No, watching motivational videos all day long won’t help you reach your goals. But, performing daily consistent actions, sustained over a long period of time will. Staying calm and focusing on the one task in front of you every day will. The point is, to achieve long-term goals in your personal or professional life, you must regain control of your attention and rewire your brain to focus on the long term. To do so, you should start by staying away from highly stimulating activities.

As information processing machines, our ability to process data about the external world begins at the level of sensory perception. Although most of us are rarely aware of it, our sensory receptors are designed to detect information at the energy level. Because everything around us - the air we breathe, even the materials we use to build with, are composed of spinning and vibrating atomic particles, you and I are literally swimming in a turbulent sea of electromagnetic fields. We are part of it. We are enveloped within in, and through our sensory apparatus we experience what is. Each of our sensory systems is made up of a complex cascade of neurons that process the incoming neural code from the level of the receptor to specific areas within the brain. Each group of neurons along the cascade alters or enhances the code, and passes it on to the next set of cells in the system, which further defines and refines the message. By the time the code reaches the outermost portion of our brain, the higher levels of the cerebral cortex, we become conscious of the stimulation. However, if any of the cells along the pathway fail in their ability to function normally, then the final perception is skewed away from normal reality.

My general philosophy regarding endurance contains four key points: 1. Build a great aerobic base. This essential physical and metabolic foundation helps accomplish several important tasks: it prevents injury and maintains a balanced physical body; it increases fat burning for improved stamina, weight loss, and sustained energy; and it improves overall health in the immune and hormonal systems, the intestines and liver, and throughout the body. 2. Eat well. Specific foods influence the developing aerobic system, especially the foods consumed in the course of a typical day. Overall, diet can significantly influence your body’s physical, chemical, and mental state of fitness and health. 3. Reduce stress. Training and competition, combined with other lifestyle factors, can be stressful and adversely affect performance, cause injuries, and even lead to poor nutrition because they can disrupt the normal digestion and absorption of nutrients. 4. Improve brain function. The brain and entire nervous system control virtually all athletic activity, and a healthier brain produces a better athlete. Improved brain function occurs from eating well, controlling stress, and through sensory stimulation, which includes proper training and optimal breathing.

are out of balance, your life quality diminishes substantially. The hormones estrogen, progesterone, and testosterone make us men and women. Every woman and man has different hormonal requirements. That’s why there is no “one pill fits all” solution. Your hormonal requirements are unique. What you need is different from what I need. This is what hormones “do”; now you might be wondering what they are made of—what they are exactly? A hormone is a chemical substance produced in your body by your glands. They are a complex combination of chemical keys that turn important metabolic locks in our cells, tissues, and organs. All the approximately sixty to ninety trillion cells in our bodies are influenced to some degree by these amazing hormonal keys. The turning on of these “locks” stimulates activity within the cells of our brain, intestines, muscles, genital organs, and skin. As such, hormones determine the rate at which our cells burn up nutrients and other food substances, release energy, and determine whether our cells should produce milk, hair, secretions, enzymes, or some other metabolic (life) product. Hormones affect virtually every function in your body. They affect your mood, how you cope, your sexuality, your sex drive. We all have hormones and without them

When applied to the prefrontal lobes, TMS has been shown to enhance the speed and agility of cognitive processing. The TMS bursts are like a localized jolt of caffeine, but nobody knows for sure how the magnets actually do their work.” These experiments hint, but by no means prove, that silencing a part of the left frontotemporal region could initiate some enhanced skills. These skills are a far cry from savant abilities, and we should also be careful to point out that other groups have looked into these experiments, and the results have been inconclusive. More experimental work must be done, so it is still too early to render a final judgment one way or the other. TMS probes are the easiest and most convenient instrument to use for this purpose, since they can selectively silence various parts of the brain at will without relying on brain damage and traumatic accidents. But it should also be noted that TMS probes are still crude, silencing millions of neurons at a time. Magnetic fields, unlike electrical probes, are not precise but spread out over several centimeters. We know that the left anterior temporal and orbitofrontal cortices are damaged in savants and likely responsible, at least in some part, for their unique abilities, but perhaps the specific area that must be dampened is an even smaller subregion. So each jolt of TMS might inadvertently deactivate some of the areas that need to remain intact in order to produce savantlike skills. In the future, with TMS probes we might be able to narrow down the region of the brain involved with eliciting savant skills. Once this region is identified, the next step would be to use highly accurate electrical probes, like those used in deep brain stimulation, to dampen these areas even more precisely. Then, with the push of a button, it might be possible to use these probes to silence this tiny portion of the brain in order to bring out savantlike skills. FORGETTING TO FORGET AND PHOTOGRAPHIC MEMORY Although savant skills may be initiated by some sort of injury to the left brain (leading to right brain compensation), this still does not explain precisely how the right brain can perform these miraculous feats of memory. By what neural mechanism does photographic memory emerge? The answer to this question may determine whether we can become savants. Until recently, it was thought that photographic memory was due to the special ability of certain brains to remember. If so, then it might be difficult for the average person to learn these memory skills, since only exceptional brains are capable of them. But in 2012, a new study showed that precisely the opposite may be true. The key to photographic memory may not be the ability of remarkable brains to learn; on the contrary, it may be their inability to forget. If this is true, then perhaps photographic memory is not such a mysterious thing after all.

Also bearing witness to the unbearable nature of the vulnerability experienced by peer-oriented kids is the preponderance of vulnerability-quelling drugs. Peer-oriented kids will do anything to avoid the human feelings of aloneness, suffering, and pain, and to escape feeling hurt, exposed, alarmed, insecure, inadequate, or self-conscious. The older and more peer-oriented the kids, the more drugs seem to be an inherent part of their lifestyle. Peer orientation creates an appetite for anything that would reduce vulnerability. Drugs are emotional painkillers. And, in another way, they help young people escape from the benumbed state imposed by their defensive emotional detachment. With the shutdown of emotions come boredom and alienation. Drugs provide an artificial stimulation to the emotionally jaded. They heighten sensation and provide a false sense of engagement without incurring the risks of genuine openness. In fact, the same drug can play seemingly opposite functions in an individual. Alcohol and marijuana, for example, can numb or, on the other hand, free the brain and mind from social inhibitions. Other drugs are stimulants — cocaine, amphetamines, and ecstasy; the very name of the latter speaks volumes about exactly what is missing in the psychic life of our emotionally incapacitated young people. The psychological function served by these drugs is often overlooked by well-meaning adults who perceive the problem to be coming from outside the individual, through peer pressure and youth culture mores. It is not just a matter of getting our children to say no. The problem lies much deeper. As long as we do not confront and reverse peer orientation among our children, we are creating an insatiable appetite for these drugs. The affinity for vulnerability-reducing drugs originates from deep within the defended soul. Our children's emotional safety can come only from us: then they will not be driven to escape their feelings and to rely on the anesthetic effects of drugs. Their need to feel alive and excited can and should arise from within themselves, from their own innately limitless capacity to be engaged with the universe. This brings us back to the essential hierarchical nature of attachment. The more the child needs attachment to function, the more important it is that she attaches to those responsible for her. Only then can the vulnerability that is inherent in emotional attachment be endured. Children don't need friends, they need parents, grandparents, adults who will assume the responsibility to hold on to them. The more children are attached to caring adults, the more they are able to interact with peers without being overwhelmed by the vulnerability involved. The less peers matter, the more the vulnerability of peer relationships can be endured. It is exactly those children who don't need friends who are more capable of having friends without losing their ability to feel deeply and vulnerably. But why should we want our children to remain open to their own vulnerability? What is amiss when detachment freezes the emotions in order to protect the child?

Scholars once proclaimed that the agricultural revolution was a great leap forward for humanity. They told a tale of progress fuelled by human brain power. Evolution gradually produced ever more intelligent people. Eventually, people were so smart that they were able to decipher nature’s secrets, enabling them to tame sheep and cultivate wheat. As soon as this happened, they cheerfully abandoned the gruelling, dangerous, and often spartan life of hunter-gatherers, settling down to enjoy the pleasant, satiated life of farmers. Map 2. Locations and dates of agricultural revolutions. The data is contentious, and the map is constantly being redrawn to incorporate the latest archaeological discoveries.1 {Maps by Neil Gower} That tale is a fantasy. There is no evidence that people became more intelligent with time. Foragers knew the secrets of nature long before the Agricultural Revolution, since their survival depended on an intimate knowledge of the animals they hunted and the plants they gathered. Rather than heralding a new era of easy living, the Agricultural Revolution left farmers with lives generally more difficult and less satisfying than those of foragers. Hunter-gatherers spent their time in more stimulating and varied ways, and were less in danger of starvation and disease. The Agricultural Revolution certainly enlarged the sum total of food at the disposal of humankind, but the extra food did not translate into a better diet or more leisure. Rather, it translated into population explosions and pampered elites. The average farmer worked harder than the average forager, and got a worse diet in return. The Agricultural Revolution was history’s biggest fraud.2 Who was responsible? Neither kings, nor priests, nor merchants. The culprits were a handful of plant species, including wheat, rice and potatoes. These plants domesticated Homo sapiens, rather than vice versa.

The brain is wired to minimize loss . . . [and] to keep you alive. [It] makes the assumption that because you were alive yesterday, what you did previously is safe. Therefore, repeating the past is good for survival. As a result, doing things differently, even if it seems like an improvement, is risky. Perpetuating past behaviors, from the brain’s reptilian perspective, is the safest way. This is why innovation is difficult for most individuals and organizations. Put another way, the brain wants its problems and predicaments solved first because it can’t deal with anything new or different until they are addressed. The brain has no incentive to come up with new ideas if it doesn’t have to. As long as your brain knows you have another out, it will always be content with keeping you alive by coming up with the same ideas that it used before. This suggests that when you decide to get scrappy, a shift occurs and seems to unlock a door. Once that new door opens, you are more capable than ever of getting innovative because your brain has been activated to manage discomfort or challenges first. You’re able to work on a new, perhaps more advanced, level with heightened energy and focus. It’s that initial commitment, that literal act of saying, “I’m going for it!” that stimulates your mind in new and clever ways and ultimately leads to the generation of fresh ideas. Let’s go back to the Greg Hague story. 1. He had a huge goal, which was to pass the Arizona state bar exam. 2. There was a limited time frame as he had only four and a half months to study. 3. He was all in: “I flat out made up my mind I was going to pass.” He decided to go despite the odds. 4. He had to figure out a way to learn a ton of information in a short period of time. His brain adapted, shifted, and developed an entirely new learning system in order to absorb more material, which helped him to pass the Arizona bar and get the top score in the state. It’s weird, right? But it happened.

As respects its isolation and its indifference to the basic requirements of all organic activity, the pecuniary power complex discloses a startling resemblance to a newly discovered center in the brain-that which is called the pleasure center. So far as is known, this pleasure center performs no useful function in the organism, unless it should prove that in some still obscure way it plays a part in more functional pleasure reactions. But in laboratory monkeys this localized center can be penetrated by electrodes which permit a micro-current to stimulate the nervous tissue in such a fashion that the flow of current-and hence the intensity of pleasure-can be regulated by the animal himself. Apparently the stimulation of this pleasure center is so rewarding that the animal will continue to press the current regulator for an indefinite length of time, regardless of every other impulse or physiological need, even that for food, and even to the point of starvation. The intensity of this abstract stimulus produces something like a total neurotic insensibility to life needs. The power complex seems to operate on the same principle. The magical electronic stimulus is money. What increases the resemblance between this pecuniary motivation and that of the cerebral pleasure center is that both centers, unlike virtually all organic reactions, recognize no quantitative limits. What has always been true of money, among those susceptible to its influence, applies equally to the other components of the power complex: the abstraction replaces the concrete reality, and therefore those who seek to increase it never know when they have had enough. Each of these drives, for power, for goods, for fame, for pleasure, may-it goes without saying-have as useful a part to play in the normal economy of a community as in the human body itself. It is by their detachment, their isolation, their quantitative over-concentration, and their mutual re-enforcement that they become perverse and life-corroding.

Nobel laureate Richard Feynman, always curious about new phenomena, once placed himself in a sensory deprivation tank and tried to leave his physical body. He was successful. He would later write that he felt that he had left his body, drifted into space, and saw his motionless body when he looked back. However, Feynman later concluded that this was probably just his imagination, caused by sensory deprivation. Neurologists who have studied this phenomenon have a more prosaic explanation. Dr. Olaf Blanke and his colleagues in Switzerland may have located the precise place in the brain that generates out-of-body experiences. One of his patients was a forty-three-year-old woman who suffered from debilitating seizures that came from her right temporal lobe. A grid of about one hundred electrodes was placed over her brain in order to locate the region responsible for her seizures. When the electrodes stimulated the area between the parietal and temporal lobes, she immediately had the sensation of leaving her body. “I see myself lying in bed, from above, but I only see my legs and lower trunk!” she exclaimed. She felt she was floating six feet above her body. When the electrodes were turned off, however, the out-of-body sensation disappeared immediately. In fact, Dr. Blanke found that he could turn the out-of-body sensation on and off, like a light switch, by repeatedly stimulating this area of the brain. As we saw in Chapter 9, temporal lobe epileptic lesions can induce the feeling that there are evil spirits behind every misfortune, so the concept of spirits leaving the body is perhaps part of our neural makeup. (This may also explain the presence of supernatural beings. When Dr. Blanke analyzed a twenty-two-year-old woman who was suffering from intractable seizures, he found that, by stimulating the temporoparietal area of the brain, he could induce the sensation that there was a shadowy presence behind her. She could describe this person, who even grabbed her arms, in detail. His position would change with each appearance, but he would always appear behind her.)

This curious effect was noticed as far back as 1892, when textbooks on mental illness noted a link between “religious emotionalism” and epilepsy. It was first clinically described in 1975 by neurologist Norman Geschwind of Boston Veterans Administration Hospital. He noticed that epileptics who had electrical misfirings in their left temporal lobes often had religious experiences, and he speculated that the electrical storm in the brain somehow was the cause of these religious obsessions. Dr. V. S. Ramachandran estimates that 30 to 40 percent of all the temporal lobe epileptics whom he has seen suffer from hyperreligiosity. He notes, “Sometimes it’s a personal God, sometimes it’s a more diffuse feeling of being one with the cosmos. Everything seems suffused with meaning. The patient will say, ‘Finally, I see what it is all really about, Doctor. I really understand God. I understand my place in the universe—the cosmic scheme.’ ” He also notes that many of these individuals are extremely adamant and convincing in their beliefs. He says, “I sometimes wonder whether such patients who have temporal lobe epilepsy have access to another dimension of reality, a wormhole of sorts into a parallel universe. But I usually don’t say this to my colleagues, lest they doubt my sanity.” He has experimented on patients with temporal lobe epilepsy, and confirmed that these individuals had a strong emotional reaction to the word “God” but not to neutral words. This means that the link between hyperreligiosity and temporal lobe epilepsy is real, not just anecdotal. Psychologist Michael Persinger asserts that a certain type of transcranial electrical stimulation (called transcranial magnetic simulation, or TMS) can deliberately induce the effect of these epileptic lesions. If this is so, is it possible that magnetic fields can be used to alter one’s religious beliefs? In Dr. Persinger’s studies, the subject places a helmet on his head (dubbed the “God helmet”), which contains a device that can send magnetism into particular parts of the brain. Afterward, when the subject is interviewed, he will often claim that he was in the presence of some great spirit. David Biello, writing in Scientific American, says, “During the three-minute bursts of stimulation, the affected subjects translated this perception of the divine into their own cultural and religious language—terming it God, Buddha, a benevolent presence, or the wonder of the universe.” Since this effect is reproducible on demand, it indicates that perhaps the brain is hardwired in some way to respond to religious feelings.

Scientists have found that there are two important genes, the CREB activator (which stimulates the formation of new connections between neurons) and the CREB repressor (which suppresses the formation of new memories). Dr. Jerry Yin and Timothy Tully of Cold Spring Harbor have been doing interesting experiments with fruit flies. Normally it takes ten trials for them to learn a certain task (e.g., detecting an odor, avoiding a shock). Fruit flies with an extra CREB repressor gene could not form lasting memories at all, but the real surprise came when they tested fruit flies with an extra CREB activator gene. They learned the task in just one session. “This implies these flies have a photographic memory,” says Dr. Tully. He said they are just like students “who could read a chapter of a book once, see it in their mind, and tell you that the answer is in paragraph three of page two seventy-four.” This effect is not just restricted to fruit flies. Dr. Alcino Silva, also at Cold Spring Harbor, has been experimenting with mice. He found that mice with a defect in their CREB activator gene were virtually incapable of forming long-term memories. They were amnesiac mice. But even these forgetful mice could learn a bit if they had short lessons with rest in between. Scientists theorize that we have a fixed amount of CREB activator in the brain that can limit the amount we can learn in any specific time. If we try to cram before a test, it means that we quickly exhaust the amount of CREB activators, and hence we cannot learn any more—at least until we take a break to replenish the CREB activators. “We can now give you a biological reason why cramming doesn’t work,” says Dr. Tully. The best way to prepare for a final exam is to mentally review the material periodically during the day, until the material becomes part of your long-term memory. This may also explain why emotionally charged memories are so vivid and can last for decades. The CREB repressor gene is like a filter, cleaning out useless information. But if a memory is associated with a strong emotion, it can either remove the CREB repressor gene or increase levels of the CREB activator gene. In the future, we can expect more breakthroughs in understanding the genetic basis of memory. Not just one but a sophisticated combination of genes is probably required to shape the enormous capabilities of the brain. These genes, in turn, have counterparts in the human genome, so it is a distinct possibility that we can also enhance our memory and mental skills genetically. However, don’t think that you will be able to get a brain boost anytime soon. Many hurdles still remain. First, it is not clear if these results apply to humans.

Dr. Hobson (with Dr. Robert McCarley) made history by proposing the first serious challenge to Freud’s theory of dreams, called the “activation synthesis theory.” In 1977, they proposed the idea that dreams originate from random neural firings in the brain stem, which travel up to the cortex, which then tries to make sense of these random signals. The key to dreams lies in nodes found in the brain stem, the oldest part of the brain, which squirts out special chemicals, called adrenergics, that keep us alert. As we go to sleep, the brain stem activates another system, the cholinergic, which emits chemicals that put us in a dream state. As we dream, cholinergic neurons in the brain stem begin to fire, setting off erratic pulses of electrical energy called PGO (pontine-geniculate-occipital) waves. These waves travel up the brain stem into the visual cortex, stimulating it to create dreams. Cells in the visual cortex begin to resonate hundreds of times per second in an irregular fashion, which is perhaps responsible for the sometimes incoherent nature of dreams. This system also emits chemicals that decouple parts of the brain involved with reason and logic. The lack of checks coming from the prefrontal and orbitofrontal cortices, along with the brain becoming extremely sensitive to stray thoughts, may account for the bizarre, erratic nature of dreams. Studies have shown that it is possible to enter the cholinergic state without sleep. Dr. Edgar Garcia-Rill of the University of Arkansas claims that meditation, worrying, or being placed in an isolation tank can induce this cholinergic state. Pilots and drivers facing the monotony of a blank windshield for many hours may also enter this state. In his research, he has found that schizophrenics have an unusually large number of cholinergic neurons in their brain stem, which may explain some of their hallucinations. To make his studies more efficient, Dr. Allan Hobson had his subjects put on a special nightcap that can automatically record data during a dream. One sensor connected to the nightcap registers the movements of a person’s head (because head movements usually occur when dreams end). Another sensor measures movements of the eyelids (because REM sleep causes eyelids to move). When his subjects wake up, they immediately record what they dreamed about, and the information from the nightcap is fed into a computer. In this way, Dr. Hobson has accumulated a vast amount of information about dreams. So what is the meaning of dreams? I asked him. He dismisses what he calls the “mystique of fortune-cookie dream interpretation.” He does not see any hidden message from the cosmos in dreams. Instead, he believes that after the PGO waves surge from the brain stem into the cortical areas, the cortex is trying to make sense of these erratic signals and winds up creating a narrative out of them: a dream.

It’s a perspective on story that may also shed light on why you and I and everyone else spend a couple of hours each day concocting tales that we rarely remember and more rarely share. By day I mean night, and the tales are those we produce during REM sleep. Well over a century since Freud’s The Interpretation of Dreams, there is still no consensus on why we dream. I read Freud’s book for a junior-year high school class called Hygiene (yes, that’s really what it was called), a somewhat bizarre requirement taught by the school’s gym teachers and sports coaches that focused on first aid and common standards of cleanliness. Lacking material to fill an entire semester, the class was padded by mandatory student presentations on topics deemed loosely relevant. I chose sleep and dreams and probably took it all too seriously, reading Freud and spending after-school hours combing through research literature. The wow moment for me, and for the class too, was the work of Michel Jouvet, who in the late 1950s explored the dream world of cats.32 By impairing part of the cat brain (the locus coeruleus, if you like that sort of thing), Jouvet removed a neural block that ordinarily prevents dream thoughts from stimulating bodily action, resulting in sleeping cats who crouched and arched and hissed and pawed, presumably reacting to imaginary predators and prey. If you didn’t know the animals were asleep, you might think they were practicing a feline kata. More recently, studies on rats using more refined neurological probes have shown that their brain patterns when dreaming so closely match those recorded when awake and learning a new maze that researchers can track the progress of the dreaming rat mind as it retraces its earlier steps.33 When cats and rats dream it surely seems they’re rehearsing behaviors relevant to survival. Our common ancestor with cats and rodents lived some seventy or eighty million years ago, so extrapolating a speculative conclusion across species separated by tens of thousands of millennia comes with ample warning labels. But one can imagine that our language-infused minds may produce dreams for a similar purpose: to provide cognitive and emotional workouts that enhance knowledge and exercise intuition—nocturnal sessions on the flight simulator of story. Perhaps that is why in a typical life span we each spend a solid seven years with eyes closed, body mostly paralyzed, consuming our self-authored tales.34 Intrinsically, though, storytelling is not a solitary medium. Storytelling is our most powerful means for inhabiting other minds. And as a deeply social species, the ability to momentarily move into the mind of another may have been essential to our survival and our dominance. This offers a related design rationale for coding story into the human behavioral repertoire—for identifying, that is, the adaptive utility of our storytelling instinct.

This transmutation of the reproductive energy gives great vitality to those practicing it. They will be filled with great vital force, which will radiate from them and will manifest in what has been called "personal magnetism." The energy thus transmuted may be turned into new channels and used to great advantage. Nature has condensed one of its most powerful manifestations of prana into reproductive energy, as its purpose is to create. The greatest amount of vital force is concentrated in the smallest area. The reproductive organism is the most powerful storage battery in animal life, and its force can be drawn upward and used, as well as expended in the ordinary functions of reproduction, or wasted in riotous lust. The majority of our students know something of the theories of regeneration; and we can do little more than to state the above facts, without attempting to prove them. The Yogi exercise for transmuting reproductive energy is simple. It is coupled with rhythmic breathing, and can be easily performed. It may be practiced at any time, but is specially recommended when one feels the instinct most strongly, at which time the reproductive energy is manifesting and may be most easily transmuted for regenerative purposes. The exercise is as follows: Keep the mind fixed on the idea of Energy, and away from ordinary sexual thoughts or imaginings. If these thoughts come into the mind do not be discouraged, but regard them as manifestations of a force which you intend using for the purposes of strengthening the body and mind. Lie passively or sit erect, and fix your mind on the idea of drawing the reproductive energy upward to the Solar Plexus, where it will be transmuted and stored away as a reserve force of vital energy. Then breathe rhythmically, forming the mental image of drawing up the reproductive energy with each inhalation. With each inhalation make a command of the Will that the energy be drawn upward from the reproductive organization to the Solar Plexus. If the rhythm is fairly established and the mental image is clear, you will be conscious of the upward passage of the energy, and will feel its stimulating effect. If you desire an increase in mental force, you may draw it up to the brain instead of to the Solar Plexus, by giving the mental command and holding the mental image of the transmission to the brain. The man or woman doing metal creative work, or bodily creative work, will be able to use this creative energy in their work by following the above exercise, drawing up the energy with the inhalation and sending it forth with the exhalation. In this last form of exercise, only such portions as are needed in the work will pass into the work being done, the balance remaining stored up in the Solar Plexus. You will understand, of course, that it is not the reproductive fluids which are drawn up and used, but the etheripranic energy which animates the latter, the soul of the reproductive organism, as it were. It is usual to allow the head to bend forward easily and naturally during the transmuting exercise.

All the substances that are the main drugs of abuse today originate in natural plant products and have been known to human beings for thousands of years. Opium, the basis of heroin, is an extract of the Asian poppy Papaver somniferum. Four thousand years ago, the Sumerians and Egyptians were already familiar with its usefulness in treating pain and diarrhea and also with its powers to affect a person’s psychological state. Cocaine is an extract of the leaves of Erythroxyolon coca, a small tree that thrives on the eastern slopes of the Andes in western South America. Amazon Indians chewed coca long before the Conquest, as an antidote to fatigue and to reduce the need to eat on long, arduous mountain journeys. Coca was also venerated in spiritual practices: Native people called it the Divine Plant of the Incas. In what was probably the first ideological “War on Drugs” in the New World, the Spanish invaders denounced coca’s effects as a “delusion from the devil.” The hemp plant, from which marijuana is derived, first grew on the Indian subcontinent and was christened Cannabis sativa by the Swedish scientist Carl Linnaeus in 1753. It was also known to ancient Persians, Arabs and Chinese, and its earliest recorded pharmaceutical use appears in a Chinese compendium of medicine written nearly three thousand years ago. Stimulants derived from plants were also used by the ancient Chinese, for example in the treatment of nasal and bronchial congestion. Alcohol, produced by fermentation that depends on microscopic fungi, is such an indelible part of human history and joy making that in many traditions it is honoured as a gift from the gods. Contrary to its present reputation, it has also been viewed as a giver of wisdom. The Greek historian Herodotus tells of a tribe in the Near East whose council of elders would never sustain a decision they made when sober unless they also confirmed it under the influence of strong wine. Or, if they came up with something while intoxicated, they would also have to agree with themselves after sobering up. None of these substances could affect us unless they worked on natural processes in the human brain and made use of the brain’s innate chemical apparatus. Drugs influence and alter how we act and feel because they resemble the brain’s own natural chemicals. This likeness allows them to occupy receptor sites on our cells and interact with the brain’s intrinsic messenger systems. But why is the human brain so receptive to drugs of abuse? Nature couldn’t have taken millions of years to develop the incredibly intricate system of brain circuits, neurotransmitters and receptors that become involved in addiction just so people could get “high” to escape their troubles or have a wild time on a Saturday night. These circuits and systems, writes a leading neuroscientist and addiction researcher, Professor Jaak Panksepp, must “serve some critical purpose other than promoting the vigorous intake of highly purified chemical compounds recently developed by humans.” Addiction may not be a natural state, but the brain regions it subverts are part of our central machinery of survival.

For instance, emotional memories are stored in the amygdala, but words are recorded in the temporal lobe. Meanwhile, colors and other visual information are collected in the occipital lobe, and the sense of touch and movement reside in the parietal lobe. So far, scientists have identified more than twenty categories of memories that are stored in different parts of the brain, including fruits and vegetables, plants, animals, body parts, colors, numbers, letters, nouns, verbs, proper names, faces, facial expressions, and various emotions and sounds. Figure 11. This shows the path taken to create memories. Impulses from the senses pass through the brain stem, to the thalamus, out to the various cortices, and then to the prefrontal cortex. They then pass to the hippocampus to form long-term memories. (illustration credit 5.1) A single memory—for instance, a walk in the park—involves information that is broken down and stored in various regions of the brain, but reliving just one aspect of the memory (e.g., the smell of freshly cut grass) can suddenly send the brain racing to pull the fragments together to form a cohesive recollection. The ultimate goal of memory research is, then, to figure out how these scattered fragments are somehow reassembled when we recall an experience. This is called the “binding problem,” and a solution could potentially explain many puzzling aspects of memory. For instance, Dr. Antonio Damasio has analyzed stroke patients who are incapable of identifying a single category, even though they are able to recall everything else. This is because the stroke has affected just one particular area of the brain, where that certain category was stored. The binding problem is further complicated because all our memories and experiences are highly personal. Memories might be customized for the individual, so that the categories of memories for one person may not correlate with the categories of memories for another. Wine tasters, for example, may have many categories for labeling subtle variations in taste, while physicists may have other categories for certain equations. Categories, after all, are by-products of experience, and different people may therefore have different categories. One novel solution to the binding problem uses the fact that there are electromagnetic vibrations oscillating across the entire brain at roughly forty cycles per second, which can be picked up by EEG scans. One fragment of memory might vibrate at a very precise frequency and stimulate another fragment of memory stored in a distant part of the brain. Previously it was thought that memories might be stored physically close to one another, but this new theory says that memories are not linked spatially but rather temporally, by vibrating in unison. If this theory holds up, it means that there are electromagnetic vibrations constantly flowing through the entire brain, linking up different regions and thereby re-creating entire memories. Hence the constant flow of information between the hippocampus, the prefrontal cortex, the thalamus, and the different cortices might not be entirely neural after all. Some of this flow may be in the form of resonance across different brain structures.

10 Practical Strategies to Improve Your Critical Thinking Skills and Unleash Your Creativity In today's rapidly changing world, the ability to think critically and creatively has become more important than ever. Whether you're a student looking to excel academically, a professional striving for success in your career, or simply someone who wants to navigate life's challenges with confidence, developing strong critical thinking skills is crucial. In this blog post, we will explore ten practical strategies to help you improve your critical thinking abilities and unleash your creative potential. 1. Embrace open-mindedness: One of the cornerstones of critical thinking is being open to different viewpoints and perspectives. Cultivate a willingness to listen to others, consider alternative opinions, and challenge your own beliefs. This practice expands your thinking and encourages creative problem-solving. 2. Ask thought-provoking questions: Asking insightful questions is a powerful way to stimulate critical thinking. By questioning assumptions, seeking clarity, and exploring deeper meanings, you can uncover new insights and perspectives. Challenge yourself to ask thought-provoking questions regularly. 3. Practice active listening: Listening actively involves not just hearing, but also understanding, interpreting, and empathizing with the speaker. By honing your active listening skills, you can better grasp complex ideas, identify underlying assumptions, and engage in more meaningful discussions. 4. Seek diverse sources of information: Expand your knowledge base by seeking information from a wide range of sources. Engage with diverse perspectives, opinions, and ideas through books, articles, podcasts, and documentaries. This habit broadens your understanding and encourages critical thinking by exposing you to different viewpoints. 5. Develop analytical thinking skills: Analytical thinking involves breaking down complex problems into smaller components, examining relationships and patterns, and drawing logical conclusions. Enhance your analytical skills by practicing activities like puzzles, riddles, and brain teasers. This will sharpen your ability to analyze information and think critically. 6. Foster a growth mindset: A growth mindset is the belief that your abilities can be developed through dedication and hard work. Embracing this mindset encourages you to view challenges as opportunities for growth, rather than obstacles. By persisting through difficulties, you build resilience and enhance your critical thinking abilities. 7. Engage in collaborative problem-solving: Collaborating with others on problem-solving tasks can spark creativity and strengthen critical thinking skills. Seek out group projects, brainstorming sessions, or online forums where you can exchange ideas, challenge each other's thinking, and find innovative solutions together. 8. Practice reflective thinking: Taking time to reflect on your thoughts, actions, and experiences allows you to gain deeper insights and learn from past mistakes. Regularly engage in activities like journaling, meditation, or self-reflection exercises to develop your reflective thinking skills. This practice enhances your critical thinking abilities by promoting self-awareness and self-improvement. 9. Encourage creativity through experimentation: Creativity and critical thinking often go hand in hand. Give yourself permission to experiment and explore new ideas without fear of failure. Embrace a "what if" mindset and push the boundaries of your thinking. This willingness to take risks and think outside the box can lead to breakthroughs in critical thinking. 10. Continuously learn and adapt: Critical thinking is a skill that can be honed throughout your life. Commit to lifelong learning and seek opportunities to expand your knowledge and skills. Stay curious, be open to new experiences, and embrace change.