Biotechnology Knowledge Quotes

To see the future of science, take a peek inside a lab at the Manchester Institute of Biotechnology, where a robot by the name of Adam is hard at work figuring out which genes encode which enzymes in yeast. Adam has a model of yeast metabolism and general knowledge of genes and proteins. It makes hypotheses, designs experiments to test them, physically carries them out, analyzes the results, and comes up with new hypotheses until it’s satisfied. Today, human scientists still independently check Adam’s conclusions before they believe them, but tomorrow they’ll leave it to robot scientists to check each other’s hypotheses.

Just as no one in 1900 could have foreseen the consequences of innovations made during the twentieth century – including whole new fields such as nuclear physics, computer science and biotechnology – so our own future will be shaped by knowledge that we do not yet have.

P2 - We are well on the way in a number of areas. Both billionaires and big Pharma are getting increasingly interested and money is starting to pour into research because it is clear we can see the light at the end of the tunnel which to investors equates to return on investment. Numerous factors will drive things forward and interest and awareness is increasing rapidly among both scientists, researchers and the general population as well as wealthy philanthropists. The greatest driving force of all is that the baby boomers are aging and this will place increasing demands on healthcare systems. Keep in mind that the average person costs more in medical expenditure in the last year of their life than all the other years put together. Also, the number of workers is declining in most developed countries which means that we need to keep the existing population working and productive as long as possible. Below are a list which are basically all technologies potentially leading to radical life extension with number 5 highlighted which I assume might well be possible in the second half of the century: 1. Biotechnology - e.g stem cell therapies, enhanced autophagy, pharmaceuticals, immunotherapies, etc 2. Nanotechnology - Methods of repairing the body at a cellular and molecular level such as nanobots. 3. Robotics - This could lead to the replacement of increasing numbers of body parts and tends to go hand in hand with AI and whole brain emulation. It can be argued that this is not life extension and that it is a path toward becoming a Cyborg but I don’t share that view because even today we don’t view a quadriplegic as less human if he has four bionic limbs and this will hold true as our technology progresses. 4. Gene Therapies - These could be classified under the first category but I prefer to look at it separately as it could impact the function of the body in very dramatic ways which would suppress genes that negatively impact us and enhance genes which increase our tendency toward longer and healthier lives. 5. Whole brain emulation and mindscaping - This is in effect mind transfer to a non biological host although it could equally apply to uploading the brain to a new biological brain created via tissue engineering this has the drawback that if the original brain continues to exist the second brain would have a separate existence in other words whilst you are identical at the time of upload increasing divergence over time will be inevitable but it means the consciousness could never die provided it is appropriately backed up. So what is the chance of success with any of these? My answer is that in order for us to fail to achieve radical life extension by the middle of the century requires that all of the above technologies must also fail to progress which simply won't happen and considering the current rate of development which is accelerating exponentially and then factoring in that only one or two of the above are needed to achieve life extension (although the end results would differ greatly) frankly I can’t see how we can fail to make enough progress within 10-20 years to add at least 20 to 30 years to current life expectancy from which point progress will rapidly accelerate due to increased funding turning aging at the very least into a manageable albeit a chronic incurable condition until the turn of the 22nd century. We must also factor in that there is also a possibility that we could find a faster route if a few more technologies like CRISPR were to be developed. Were that to happen things could move forward very rapidly. In the short term I'm confident that we will achieve significant positive results within a year or two in research on mice and that the knowledge acquired will then be transferred to humans within around a decade. According to ADG, a dystopian version of the post-aging world like in the film 'In Time' not plausible in the real world: "If you CAREFULLY watch just the first

Robert Freitas estimates that eliminating a specific list comprising 50 percent of medically preventable conditions would extend human life expectancy to over 150 years.39 By preventing 90 percent of medical problems, life expectancy grows to over five hundred years. At 99 percent, we’d be over one thousand years. We can expect that the full realization of the biotechnology and nanotechnology revolutions will enable us to eliminate virtually all medical causes of death. As we move toward a nonbiological existence, we will gain the means of “backing ourselves up” (storing the key patterns underlying our knowledge, skills, and personality), thereby eliminating most causes of death as we know it.

The task of wealth generation for the nation has to be woven around national competencies. The Technology Information, Forecasting and Assessment Council (TIFAC) task team has identified core areas that will spearhead our march towards becoming a knowledge society. The areas are: information technology, biotechnology, space technology, weather forecasting, disaster management, tele-medicine and tele-education, technologies utilizing traditional knowledge, service sector and infotainment which is the emerging area resulting from the convergence of information and entertainment.