Billion Dollar Brain Quotes

Brain Research Through Advancing Innovative Neurotechnologies (or BRAIN) project announced by President Obama, and the Human Brain Project of the European Union, which will potentially allocate billions of dollars to decode the pathways of the brain, all the way down to the neural level.

A’ight, so what do you think it means?” “You don’t know?” I ask. “I know. I wanna hear what YOU think.” Here he goes. Picking my brain. “Khalil said it’s about what society feeds us as youth and how it comes back and bites them later,” I say. “I think it’s about more than youth though. I think it’s about us, period.” “Us who?” he asks. “Black people, minorities, poor people. Everybody at the bottom in society.” “The oppressed,” says Daddy. “Yeah. We’re the ones who get the short end of the stick, but we’re the ones they fear the most. That’s why the government targeted the Black Panthers, right? Because they were scared of the Panthers?” “Uh-huh,” Daddy says. “The Panthers educated and empowered the people. That tactic of empowering the oppressed goes even further back than the Panthers though. Name one.” Is he serious? He always makes me think. This one takes me a second. “The slave rebellion of 1831,” I say. “Nat Turner empowered and educated other slaves, and it led to one of the biggest slave revolts in history.” “A’ight, a’ight. You on it.” He gives me dap. “So, what’s the hate they’re giving the ‘little infants’ in today’s society?” “Racism?” “You gotta get a li’l more detailed than that. Think ’bout Khalil and his whole situation. Before he died.” “He was a drug dealer.” It hurts to say that. “And possibly a gang member.” “Why was he a drug dealer? Why are so many people in our neighborhood drug dealers?” I remember what Khalil said—he got tired of choosing between lights and food. “They need money,” I say. “And they don’t have a lot of other ways to get it.” “Right. Lack of opportunities,” Daddy says. “Corporate America don’t bring jobs to our communities, and they damn sure ain’t quick to hire us. Then, shit, even if you do have a high school diploma, so many of the schools in our neighborhoods don’t prepare us well enough. That’s why when your momma talked about sending you and your brothers to Williamson, I agreed. Our schools don’t get the resources to equip you like Williamson does. It’s easier to find some crack than it is to find a good school around here. “Now, think ’bout this,” he says. “How did the drugs even get in our neighborhood? This is a multibillion-dollar industry we talking ’bout, baby. That shit is flown into our communities, but I don’t know anybody with a private jet. Do you?” “No.” “Exactly. Drugs come from somewhere, and they’re destroying our community,” he says. “You got folks like Brenda, who think they need them to survive, and then you got the Khalils, who think they need to sell them to survive. The Brendas can’t get jobs unless they’re clean, and they can’t pay for rehab unless they got jobs. When the Khalils get arrested for selling drugs, they either spend most of their life in prison, another billion-dollar industry, or they have a hard time getting a real job and probably start selling drugs again. That’s the hate they’re giving us, baby, a system designed against us. That’s Thug Life.

I am saddened by the fact that the billion-dollar psychotropic pharmaceutical industry is predicated on the idea that people will take a pill to treat symptoms, while the underlying disorder is ignored.

The next time you drive into a Walmart parking lot, pause for a second to note that this Walmart—like the more than five thousand other Walmarts across the country—costs taxpayers about $1 million in direct subsidies to the employees who don’t earn enough money to pay for an apartment, buy food, or get even the most basic health care for their children. In total, Walmart benefits from more than $7 billion in subsidies each year from taxpayers like you. Those “low, low prices” are made possible by low, low wages—and by the taxes you pay to keep those workers alive on their low, low pay. As I said earlier, I don’t think that anyone who works full-time should live in poverty. I also don’t think that bazillion-dollar companies like Walmart ought to funnel profits to shareholders while paying such low wages that taxpayers must pick up the ticket for their employees’ food, shelter, and medical care. I listen to right-wing loudmouths sound off about what an outrage welfare is and I think, “Yeah, it stinks that Walmart has been sucking up so much government assistance for so long.” But somehow I suspect that these guys aren’t talking about Walmart the Welfare Queen. Walmart isn’t alone. Every year, employers like retailers and fast-food outlets pay wages that are so low that the rest of America ponies up a collective $153 billion to subsidize their workers. That’s $153 billion every year. Anyone want to guess what we could do with that mountain of money? We could make every public college tuition-free and pay for preschool for every child—and still have tens of billions left over. We could almost double the amount we spend on services for veterans, such as disability, long-term care, and ending homelessness. We could double all federal research and development—everything: medical, scientific, engineering, climate science, behavioral health, chemistry, brain mapping, drug addiction, even defense research. Or we could more than double federal spending on transportation and water infrastructure—roads, bridges, airports, mass transit, dams and levees, water treatment plants, safe new water pipes. Yeah, the point I’m making is blindingly obvious. America could do a lot with the money taxpayers spend to keep afloat people who are working full-time but whose employers don’t pay a living wage. Of course, giant corporations know they have a sweet deal—and they plan to keep it, thank you very much. They have deployed armies of lobbyists and lawyers to fight off any efforts to give workers a chance to organize or fight for a higher wage. Giant corporations have used their mouthpiece, the national Chamber of Commerce, to oppose any increase in the minimum wage, calling it a “distraction” and a “cynical effort” to increase union membership. Lobbyists grow rich making sure that people like Gina don’t get paid more. The

The country’s best minds increasingly were leaving, preferring a life in New York or London over the struggles in Malaysia. It was the kind of brain drain that had stunted the growth of nations from India to Indonesia, whose most ambitious citizens gave up on their troubled homeland and sought a better life elsewhere.

perform the equivalent of all human thought over the last ten thousand years (assumed at ten billion human brains for ten thousand years) in ten microseconds.64 If we examine the “Exponential Growth of Computing” chart (p. 70), we see that this amount of computing is estimated to be available for one thousand dollars by 2080.

Today, when we talk about the two atomic bombs* the United States dropped on Japan, we tend to do so in the context of the morality of dropping them. The truth is, the decision makers almost certainly didn’t have the range of options we often assume (or wish) they had. The idea that President Truman could have done something other than use the atomic bomb on Japan is probably a little out of step with the political realities of the time.* As the historian Garry Wills wrote in his book Bomb Power: “If it became known that the United States had a knockout weapon it did not use, the families of any Americans killed after the development of the bomb would be furious. The public, the press, and Congress would turn on the President and his advisors. There would have been a cry to impeach President Truman and court-martial General Groves. The administration would be convicted of spending billions of dollars and draining massive amounts of brain power and manpower from other war projects and all for nothing.

At a young age, Evan would listen in on his father’s long legal calls, which he credits for giving him early business exposure that helped develop his critical thinking and business accumen. He can often become obsessed with ideas, hungrily learning everything he can about them at a rapid pace. Evan is constantly curious and is learning and getting better at being a CEO very quickly. But his two superpowers are (1) his ability to get inside his users’ heads and think like a teenage girl and (2) his knack for attracting brilliant, powerful mentors. Evan loves picking other people’s brains over a walk or a meal. Over the years he has attracted an A-list roster of mentors, including SoftBank’s Nikesh Arora, Twitter’s Jack Dorsey and Google’s Eric Schmidt. He doesn’t just limit these brain dumps to tech luminaries, though, as he often walks and chats with fashion designers, politicians, documentary filmmakers, and other intriguing peers. Often, these impressive people will come speak to Team Snapchat at their Venice headquarters.

The popular 2020 documentary The Social Dilemma illustrates how AI’s personalization will cause you to be unconsciously manipulated by AI and motivated by profit from advertising. The Social Dilemma star Tristan Harris says: “You didn’t know that your click caused a supercomputer to be pointed at your brain. Your click activated billions of dollars of computing power that has learned much from its experience of tricking two billion human animals to click again.” And this addiction results in a vicious cycle for you, but a virtuous cycle for the big Internet companies that use this mechanism as a money-printing machine. The Social Dilemma further argues that this may narrow your viewpoints, polarize society, distort truth, and negatively affect your happiness, mood, and mental health. To put it in technical terms, the core of the issue is the simplicity of the objective function, and the danger from single-mindedly optimizing a single objective function, which can lead to harmful externalities. Today’s AI usually optimizes this singular goal—most commonly to make money (more clicks, ads, revenues). And AI has a maniacal focus on that one corporate goal, without regard for users’ well-being.

You wonder what had happened, when a feller like that, in a place like that, talked of a childhood that might have as easily belonged to a millionaire, a lawyer, a schoolteacher, you. You had to think he was defective somehow, or had fucked up not once, not twice, but again and again, a peculiar resolve to his life. That was the thing, that resolve. We didn’t credit it. You looked at him and your brain said he was on the losing end of one of the two bargains that America made with you. There was the romantic one, that of the rambler, the man out seeking his destiny, living by his wits, all that horseshit. Then there was the classical American dare, that you could risk all, take an internal grudge and make of it a billion dollars and get a monumental tomb in the bargain. But the truth was neither. America was a grindstone. She used those notions as twin abrasives to wear you down into a dutiful drudge walking the straight and narrow. But there was something in the hearts of the some men, some of whom became Fritz, that wouldn’t accept that. These men in crummy bars, some of them, most of them, they were main-chance fellers. You could take ten of these wrecks and offer them a salesman’s job, a dozen white shirts and ties, forty Gs a year and perks, a neat house on a quiet street, a yard, a car, a dog, a wife, an expense account, a Chinese laundryman, membership in a church, grandkids who’d bounce on their knees, and you’d be lucky if one or two took you up on it. And those two would be the most defeated, the most broken and worn down. Take the same ten and offer them eight dollars a day to be litter bearers on a great adventure, a hike after a lost civilization, a one in hundred shot at survival, a one in thousand shot at a fabulous fortune of jewels and gold, and if you provided rum along the way, nine of the ten would sign up. I guarantee it. I guarantee too that the one or two who took the salesman’s job—within a year or two or three, he’d be fucking up again and again, no matter how many chances you gave him. He’s a main-chance feller, and even if he didn’t have the brains or the luck to make it work, he still couldn’t abide the line others toed, even if he couldn’t think of anything else to do with his life but the miserable American two step—toe the line, fuck up, toe the line, fuck up....

To their surprise, they found that dopamine actively regulates both the formation and the forgetting of new memories. In the process of creating new memories, the dCA1 receptor was activated. By contrast, forgetting was initiated by the activation of the DAMB receptor. Previously, it was thought that forgetting might be simply the degradation of memories with time, which happens passively by itself. This new study shows that forgetting is an active process, requiring intervention by dopamine. To prove their point, they showed that by interfering with the action of the dCA1 and DAMB receptors, they could, at will, increase or decrease the ability of fruit flies to remember and forget. A mutation in the dCA1 receptor, for example, impaired the ability of the fruit flies to remember. A mutation in the DAMB receptor decreased their ability to forget. The researchers speculate that this effect, in turn, may be partially responsible for savants’ skills. Perhaps there is a deficiency in their ability to forget. One of the graduate students involved in the study, Jacob Berry, says, “Savants have a high capacity for memory. But maybe it isn’t memory that gives them this capacity; maybe they have a bad forgetting mechanism. This might also be the strategy for developing drugs to promote cognition and memory—what about drugs that inhibit forgetting as a cognitive enhancers?” Assuming that this result holds up in human experiments as well, it could encourage scientists to develop new drugs and neurotransmitters that are able to dampen the forgetting process. One might thus be able to selectively turn on photographic memories when needed by neutralizing the forgetting process. In this way, we wouldn’t have the continuous overflow of extraneous, useless information, which hinders the thinking of people with savant syndrome. What is also exciting is the possibility that the BRAIN project, which is being championed by the Obama administration, might be able to identify the specific pathways involved with acquired savant syndrome. Transcranial magnetic fields are still too crude to pin down the handful of neurons that may be involved. But using nanoprobes and the latest in scanning technologies, the BRAIN project might be able to isolate the precise neural pathways that make possible photographic memory and incredible computational, artistic, and musical skills. Billions of research dollars will be channeled into identifying the specific neural pathways involved with mental disease and other afflictions of the brain, and the secret of savant skills may be revealed in the process. Then it might be possible to take normal individuals and make savants out of them. This has happened many times in the past because of random accidents. In the future, this may become a precise medical process.

There’s another level at which attention operates, this has to do with leadership, I argue that leaders need three kinds of focus, to be really effective, the first is an inner focus, let me tell you about a case that’s actually from the annals of neurology, there was a corporate lawyer, who unfortunately had a small prefrontal brain tumour, it was discovered early, operated successfully, after the surgery though it was a very puzzling picture, because he was absolutely as smart as he had been before, a very high IQ, no problem with attention or memory, but he couldn’t do his job anymore, he couldn’t do any job, in fact he ended up out of work, his wife left him, he lost his home, he’s living in his brother spare bedroom and in despair he went to see a famous neurologist named Antonio Damasio. Damasio specialized in the circuitry between the prefrontal area which is where we consciously pay attention to what matters now, where we make decisions, where we learn and the emotional centers in the midbrain, particularly the amygdala, which is our radar for danger, it triggers our strong emotions. They had cut the connection between the prefrontal area and emotional centers and Damasio at first was puzzled, he realized that this fellow on every neurological test was perfectly fine but something was wrong, then he got a clue, he asked the lawyer when should we have our next appointment and he realized the lawyer could give him the rational pros and cons of every hour for the next two weeks, but he didn’t know which is best. And Damasio says when we’re making a decision any decision, when to have the next appointment, should I leave my job for another one, what strategy should we follow, going into the future, should I marry this fellow compared to all the other fellows, those are decisions that require we draw on our entire life experience and the circuitry that collects that life experience is very base brain, it’s very ancient in the brain, and it has no direct connection to the part of the brain that thinks in words, it has very rich connectivity to the gastro- intestinal tract, to the gut, so we get a gut feeling, feels right, doesn’t feel right. Damasio calls them somatic markers, it’s a language of the body and the ability to tune into this is extremely important because this is valuable data too - they did a study of Californian entrepreneurs and asked them “how do you make your decisions?”, these are people who built a business from nothing to hundreds of millions or billions of dollars, and they more or less said the same strategy “I am a voracious gatherer of information, I want to see the numbers, but if it doesn’t feel right, I won’t go ahead with the deal”. They’re tuning into the gut feeling. I know someone, I grew up in farm region of California, the Central Valley and my high school had a rival high school in the next town and I met someone who went to the other high school, he was not a good student, he almost failed, came close to not graduating high school, he went to a two-year college, a community college, found his way into film, which he loved and got into a film school, in film school his student project caught the eye of a director, who asked him to become an assistant and he did so well at that the director arranged for him to direct his own film, someone else’s script, he did so well at that they let him direct a script that he had written and that film did surprisingly well, so the studio that financed that film said if you want to do another one, we will back you. And he, however, hated the way the studio edited the film, he felt he was a creative artist and they had butchered his art. He said I am gonna do the film on my own, I’m gonna finance it myself, everyone in the film business that he knew said this is a huge mistake, you shouldn’t do this, but he went ahead, then he ran out of money, had to go to eleven banks before he could get a loan, he managed to finish the film, you may have seen

Vast populations in parasitic hot zones are without hospitals, doctors, drugs, or surgical equipment. Meanwhile, often directed at the very same underserved regions, wealthy countries are throwing billions of dollars into campaigns aimed at containing wars ignited by ethnic hatred and religious intolerance, not to mention dealing with the refugee crises and other tragedies this violence has spawned. By investing more in health care up front, Thornhill’s model predicts, Western countries might not have to spend so much on warfare later—and may ultimately reduce human suffering far more effectively.

When using this technique, it’s important to refrain from projecting bias onto the subject of your concentration. If you choose to focus your attention on a person, don’t rush to judge that person as being good or bad. In many ways, the concepts of good and bad are just tools that our self-centered minds use to sort through sensory data. For example, a controlled fire at a comfortable distance feels warm, so your brain thinks that’s good. An uncontrolled fire that’s burning your hand hurts, so that’s bad. It’s the effect the fire has on you that makes your brain think it’s good or bad, not the simple fact that it’s a fire. Non-judgmental concentration trains your brain to realize that the people and things in your life don’t exist relative to you; they simply exist. If you can take yourself out of the equation, you’ll have a much clearer view. Uncluttered by judgmentalism, you can work more efficiently, because you won’t be as distracted, and you can think more objectively, too.

Your focus is a scarce asset, which is why marketers spend billions of dollars to attract your attention. Many apps are designed to hook you. Social media companies like YouTube, Facebook, and Instagram know that the more time you spend on their platforms, the more money they make through advertising. Perhaps one of their greatest recent discoveries is the use of notifications. How many times have you opened an app just because a red notification pops up on your screen? And how much time did you waste subsequently? I wouldn’t be surprised if it ran into hundreds of hours each year.

The development of AI is driven by market forces and the defense industry—billions of dollars are now pouring into constructing smart household assistants, robot supersoldiers, and supercomputers that mimic the workings of the human brain.

Your focus is a scarce asset, which is why marketers spend billions of dollars to attract your attention.

Cymbalta, an antidepressant that sold well over a billion dollars’ worth of pills,25 even though it has never been shown to be superior to older antidepressants like Prozac, for which much cheaper generics are available.

Three billion of the people on the planet – approximately half – are destitute. They live in shocking poverty. There are 10 million children dying of easily preventable causes every year - things like starvation, thirst, cholera. Billions of people lack any form of health care. Billions of people lack access to basics like clean water, adequate food and safe housing. Environmentally, we are raping the planet in hundreds of ways. A mass extinction event is looming on the horizon, yet we appear unmotivated to do anything at all to prevent it. Humans are constantly at war, constantly killing one another somewhere in the world. Crime seems rampant. In the United states, over two million citizens are incarcerated. We have thousands of nuclear warheads, enough to kill all of humanity many times over, all loaded into rockets that we can launch at a moment's notice simply by pushing a few buttons. We have spent trillions of dollars building and stockpiling conventional weapons designed to kill fellow humans in a thousand different ways. We can shoot them, bomb them, grenade them, poison them, burn them, etc. Humans often seem intent on bringing misery to other humans: terrorism, dictatorships, warlords, slavery, torture, unjust imprisonment, sweatshops, corruption, murder, mayhem, crime, etc. can be found all over the planet. The concentration of wealth is extreme and seems unstoppable, so a very small percentage of the planet's population owns half of the planet's wealth, while billions of others have nothing. In many cases and at many different levels we seem unable to control ourselves or to stop ourselves even when we know we are wrong.

The rise of the Rockefeller family was made possible from two angles by the Rothschilds. One was by the large subsidies placed on transports of Rockefeller oil. The documents of the American trade register prove that the Rothschilds, since 1896, have owned ninety-six percent of the American railways. This made it possible to transport oil on rail. When John D. Rockefeller wanted to expand, he received the financial support he needed to do so from the Rothschilds through their National City Bank of Cleveland. In exchange, the Rockefellers had to transport their oil via the Rothschilds railways. An illegal agreement saw to it that the Rockefellers received a bonus for the amount of oil they transported by train. Because of this agreement nobody could compete with the Rothschilds in transporting Rockefeller oil. This was all arranged by Jacob Schiff, of the company Kuhn & Loeb, the brain behind the foundation of the Rockefeller imperium. Under the authority of the Rothchilds, Kuhn, Loeb & Co. continue to manage the Rockefeller capital, which is valued at over 400 billion dollars. In 1950 the New York Times reported L.L. Strauss, a partner with Kuhn, Loeb & Co., as the financial adviser to the Rockefeller estate. Because of this, every investment had to be approved and signed by a partner of Kuhn, Loeb & Co. According to the periodical Fortune in 1985, the wealth of the Rockefellers was spread amongst more than 200 companies. These companies include six of the largest industrial companies in America, six of the largest banks, five of the largest insurance companies and three of the largest companies from different branches (electricity, water, infrastructure, fruits, oil, gold, and others). Not including the remaining 180 other companies, the total assets of these twenty giants amount to 460 billion dollars.

One of the most studied ideas as to what causes schizophrenia is the 'chemical imbalance theory,' which derives psychiatric pharmaceuticals themselves. Though the 'mechanism of action' of drugs marketed for their 'antipsychotic' properties isn't understood--plainly, drug companies believe these drugs are effective in lessening psychiatric symptoms, but they don't actually know why--what is known is that they affect chemical levels in the brain. It's therefore supposed that abnormal chemical levels might somehow be crucial to understanding what's different about the brains of people diagnosed with schizophrenia. Testing chemical levels inside brains remains impossible. Despite billions of dollars of investigation, the chemical imbalance theory has never been confirmed.

You mean you kidnap them, brainwash them with a dangerous drug that kills some and leaves others brain-damaged, then send the ones who are lucky enough to survive back to betray their friends so you can make a few more billion dollars? You're one sick weirdo.

So far, the smallest memory device known to be evolved and used in the wild is the genome of the bacterium Candidatus Carsonella ruddii, storing about 40 kilobytes, whereas our human DNA stores about 1.6 gigabytes, comparable to a downloaded movie. As mentioned in the last chapter, our brains store much more information than our genes: in the ballpark of 10 gigabytes electrically (specifying which of your 100 billion neurons are firing at any one time) and 100 terabytes chemically/biologically (specifying how strongly different neurons are linked by synapses). Comparing these numbers with the machine memories shows that the world’s best computers can now out-remember any biological system—at a cost that’s rapidly dropping and was a few thousand dollars in 2016.

Even if just equal in capacity to our own brains, this nonbiological portion of our intelligence will be more powerful because it will combine the pattern-recognition powers of human intelligence with the memory- and skill-sharing ability and memory accuracy of machines. The nonbiological portion will always operate at peak capacity, which is far from the case for biological humanity today; the 10²⁶ cps represented by biological human civilization today is poorly utilized. This state of computation in the early 2030s will not represent the Singularity, however, because it does not yet correspond to a profound expansion of our intelligence. By the mid-2040s, however, that one thousand dollars’ worth of computation will be equal to 10²⁶ cps, so the intelligence created per year (at a total cost of about $10¹²) will be about one billion times more powerful than all human intelligence today.⁶⁶ That will indeed represent a profound change, and it is for that reason that I set the date for the Singularity—representing a profound and disruptive transformation in human capability—as 2045. Despite the clear predominance of nonbiological intelligence by the mid-2040s, ours will still be a human civilization. We will transcend biology, but not our humanity.