Ankylosing Spondylitis Quotes

People with certain rheumatic diseases, such as rheumatoid arthritis, systemic lupus erythematosus (commonly called lupus), or ankylosing spondylitis (spinal arthritis) may be more likely to have fibromyalgia, too. Several studies indicate that women

In fact, acetaminophen is currently the leading cause of acute liver failure in both the United States

Autoimmune Disease—the “Leak” in Your Gut Autoimmune diseases are a disaster and there are no good medicines available (steroids work, but the treatment is worse than the disease). They’ve been around for centuries, but there’s been a clear uptick in the last fifty years. Why? Two hypotheses have been proffered to explain it: the barrier hypothesis (our skin or lungs are letting in antigens) and the hygiene hypothesis (we don’t eat dirt and are too hygienic). But in fact, in the gut, they’re the same thing; because the gut is the dirtiest place in the world—one hundred trillion bacteria to have to fend off at all times—you don’t need an intestine, you need a fortress. We’ve known for a while that leaky gut is akin to chinks in the walls of that fortress. Antigens, like enemy soldiers, escape through those chinks into the bloodstream, where T cells and antibodies react against them. But in a case of mistaken identity, these immune cells then accidentally identify parts of your body as foreign invaders and generate an immune response to kill them off, a process termed molecular mimicry. Then there are two new twists. First, it appears that one autoimmune disease, called ankylosing spondylitis, produces antibodies to a gut bacterium called Klebsiella pneumoniae. Conversely, a different autoimmune disease called rheumatoid arthritis produces antibodies to a second gut bacterium called Proteus mirabilis. Now, this might not seem that earth-shattering, but recent work has shown that the refined carbohydrates in processed food feed those two bacteria in particular, and that carbohydrate restriction improves both of these diseases. Indeed, a low-sugar, high-fiber Mediterranean diet has been shown to be efficacious at prevention and treatment of rheumatoid arthritis. Furthermore, introduction of fiber to the diet appears to improve asthma (frequently an autoimmune disease), likely by improving gut function and reducing inflammation.

In 1964 following a very stressful trip to Russia, [Cousins] was diagnosed with ankylosing spondylitis (a degenerative disease causing the breakdown of collagen), which left him in almost constant pain and motivated his doctor to say he would die within a few months. He disagreed and reasoned that if stress had somehow contributed to his illness (he was not sick before the trip to Russia), then positive emotions should help him feel better. With his doctors’ consent, he checked himself out of the hospital and into a hotel across the street and began taking extremely high doses of vitamin C while exposing himself to a continuous stream of humorous films and similar “laughing matters.” He later claimed that 10 minutes of belly rippling laughter would give him two hours of pain-free sleep, when nothing else, not even morphine, could help him. His condition steadily improved and he slowly regained the use of his limbs. Within six months he was back on his feet, and within two years he was able to return to his full-time job at the Saturday Review. His story baffled the scientific community and inspired a number of research projects.

In his well-known book The Anatomy of an Illness, Norman Cousins described how he overcame one of these autoimmune disorders, ankylosing spondylitis (a form of rheumatoid arthritis), by recognizing that it was emotionally induced and introducing a kind of humor therapy plus vitamin C.

Then there are two new twists. First, it appears that one autoimmune disease, called ankylosing spondylitis, produces antibodies to a gut bacterium called Klebsiella pneumoniae. Conversely, a different autoimmune disease called rheumatoid arthritis produces antibodies to a second gut bacterium called Proteus mirabilis. Now, this might not seem that earth-shattering, but recent work has shown that the refined carbohydrates in processed food feed those two bacteria in particular, and that carbohydrate restriction improves both of these diseases. Indeed, a low-sugar, high-fiber Mediterranean diet has been shown to be efficacious at prevention and treatment of rheumatoid arthritis. Furthermore, introduction of fiber to the diet appears to improve asthma (frequently an autoimmune disease), likely by improving gut function and reducing inflammation.