Alcoholism Is A Disease Quotes

I have this disease late at night sometimes, involving alcohol and the telephone.

Alcoholism is a disease with many faces, and some of them look beautiful.

Whether I or anyone else accepted the concept of alcoholism as a disease didn't matter; what mattered was that when treated as a disease, those who suffered from it were most likely to recover.

As the ACE study has shown, child abuse and neglect is the single most preventable cause of mental illness, the single most common cause of drug and alcohol abuse, and a significant contributor to leading causes of death such as diabetes, heart disease, cancer, stroke, and suicide.

The worst disease which can afflict executives in their work is not, as popularly supposed, alcoholism; it's egotism.

It was the beginning of a lesson her children would learn by heart: Alcoholism is a disease with many faces, and some of them look beautiful.

I grew up in traditional black patriarchal culture and there is no doubt that I’m going to take a great many unconscious, but present, patriarchal complicities to the grave because it so deeply ensconced in how I look at the world. Therefore, very much like alcoholism, drug addiction, or racism patriarchy is a disease and we are in perennial recovery and relapse. So you have to get up every morning and struggle against it.

People with family histories of alcoholism tend to have lower levels of endorphins- the endogenous morphine that is responsible for many of our pleasure responses- than do people genetically disinclined to alcoholism. Alcohol will slightly raise the endorphin level of people without the genetic basis for alcoholism; it will dramatically raise the endorphin level of people with that genetic basis. Specialists spend a lot of time formulating exotic hypotheses to account for substance abuse. Most experts point out, strong motivations for avoiding drugs; but there are also strong motivations for taking them. People who claim not to understand why anyone would get addicted to drugs are usually people who haven't tried them or who are genetically fairly invulnerable to them.

I have this disease late at night sometimes, involving alcohol and the telephone. I get drunk, and I drive my wife away with a breath like mustard gas and roses. And then, speaking gravely and elegantly into the telephone, I ask the telephone operators to connect me with this friend or that one, from whom I have not heard in years.

Alcoholism or addiction is a disease because it fits the definition of disease. It is progressive and chronic, and left untreated, it will kill.

You are not an alcoholic or an addict. You are not incurably diseased. You have merely become dependent on substances or addictive behavior to cope with underlying conditions that you are now going to heal, at which time your dependency will cease completely and forever.

It is difficult to feel sympathy for these people. It is difficult to regard some bawdy drunk and see them as sick and powerless. It is difficult to suffer the selfishness of a drug addict who will lie to you and steal from you and forgive them and offer them help. Can there be any other disease that renders its victims so unappealing? Would Great Ormond Street be so attractive a cause if its beds were riddled with obnoxious little criminals that had “brought it on themselves?

Alcoholism is a disease,” she said. “Like athlete’s foot. Or herpes. It’s nothing to be ashamed of. Luker and I have lots of friends who are alcoholics. And speed freaks too.” “Well,

Other illnesses, from alcoholism to heart disease, mask depression when it causes them; if one takes that into consideration, depression may be the biggest killer on earth.

What Friedan gave to the world was, "the problem that has no name." She not only named it but dissected it. The advances of science, the development of labor-saving appliances, the development of the suburbs: all had come together to offer women in the 1950s a life their mothers had scarcely dreamed of, free from rampant disease, onerous drudgery, noxious city streets. But the green lawns and big corner lots were isolating, the housework seemed to expand to fill the time available, and polio and smallpox were replaced by depression and alcoholism. All that was covered up in a kitchen conspiracy of denial... [i]nstead the problem was with the mystique of waxed floors and perfectly applied lipstick.

Alcohol is the only drug in the world where, when you stop taking it, you are seen as having a disease.

Our story gives a teaching diametrically opposite. It says that where a man’s wound is, that is where his genius will be. Wherever the wound appears in our psyches, whether from alcoholic father, shaming mother, shaming father, abusing mother, whether it stems from isolation, disability, or disease, that is precisely the place for which we will give our major gift to the community.

Alcoholics are, in truth, failures, and their failure is a simple failure of will. They have made bad choices, and they continue to do so every day. By calling them victims of a disease, we magically shift the burden of the problem from choice and personal control, where it belongs, to an impersonal force—disease.

Alcoholism is above all a disease of denial.

America today is a "save yourself" society if there ever was one. But does it really work? The underdeveloped societies suffer from one set of diseases: tuberculosis, malnutrition, pneumonia, parasites, typhoid, cholera, typhus, etc. Affluent America has virtually invented a whole new set of diseases: obesity, arteriosclerosis, heart disease, strokes, lung cancer, venereal disease, cirrhosis of the liver, drug addiction, alcoholism, divorce, battered children, suicide, murder. Take your choice. Labor-saving machines have turned out to be body-killing devices. Our affluence has allowed both mobility and isolation of the nuclear family, and as a result, our divorce courts, our prisons and our mental institutions are flooded. In saving ourselves we have nearly lost ourselves.

Donald Lydecker: Alcoholism is not a disease, it's a failing. You've turned it into a church. You worship the altar of self-pity. I come to these rooms for one reason, to remember what I don't want to become... helpless, impotent, and weak.

Explain to me, if you will, why alcoholism is a disease but can only be treated by attending little spiritual meetings in basements.

As the war progresses, and as population increases to an even more intolerable level stretching resources to impossible lengths, the strong will begin fighting for their very survival. That’s what we’re seeing right now. Society will become more and more stratified into the people who aren’t buying the bullshit in society and those who blindly follow where they are led. Satanists, freethinkers, are a burgeoning minority cause. We have an illness that needs to be recognized just like alcoholism, handicaps, addictive behaviors and AIDS. We suffer from a disease called independence — a pathological aversion to regimentation and institutionalism — which prevents us from getting ‘regular’ jobs and living a ‘normal’ life.

Trauma happens to us, our friends, our families, and our neighbors. Research by the Centers for Disease Control and Prevention has shown that one in five Americans was sexually molested as a child; one in four was beaten by a parent to the point of a mark being left on their body; and one in three couples engages in physical violence. A quarter of us grew up with alcoholic relatives, and one out of eight witnessed their mother being beaten or hit.1

The poison of skepticism becomes, like alcoholism, tuberculosis, and some other diseases, much more virulent in a hitherto virgin soil.

Walk the Bowery under the El at night and all you feel is a sort of cold guilt. Touched for a dime, you try to drop the coin and not touch the hand, because the hand is dirty; you try to avoid the glance, because the glance accuses. This is not so much personal menace as universal — the cold menace of unresolved human suffering and poverty and the advanced stages of the disease alcoholism.

Some men are dedicated to golf like I'm addicted to cheese. We have real problems, but somehow only the alcoholics get to claim a disease.

So this purports to be a disease, alcoholism? A disease like a cold? Or like cancer? I have to tell you, I have never heard of anyone being told to pray for relief from cancer. Outside maybe certain very rural parts of the American South, that is. So what is this? You’re ordering me to pray? Because I allegedly have a disease? I dismantle my life and career and entered nine months of low-income treatment for a disease, and I’m prescribed prayer? Does the word retrograde signify? Am I in a sociohistorical era I don’t know about? What exactly is the story here?

Think about the stigma that is attached to the idea that alcoholism is a disease, an incurable illness, and you have it. That's a terrible thing to inflict on someone. Labeling alcoholism as a disease, a cause unto itself, simply no longer fits with what we know today about its causes.

The reason the program is so successful is because alcoholics help other alcoholics. I've never met a Normie (our lingo for a person who doesn't have a problem with drugs and alcohol) who could even conceive of what it's like to be an alcoholic. Normies are always going, 'There's this new pill you can take and you won't want to shoot heroin anymore.' That shows a fundamental misunderstanding of alcoholism and drug addiction. These aren't just physical allergies, they're obsessions of the mind and maladies of the spirit. It's a threefold disease. And if it's partly a spiritual malady, then there's a spiritual cure.

Thinking the day of judgment was imminent, farmers did not plant crops. Many people gave themselves over to alcohol. Civil and economic disruption may have caused as much death as the disease itself.

Resentment is the “number one” offender. It destroys more alcoholics than anything else. From it stem all forms of spiritual disease, for we have been not only mentally and physically ill, we have been spiritually sick. When the spiritual malady is overcome, we straighten out mentally and physically.

Like most people who decide to get sober, I was brought to Alcoholics Anonymous. While AA certainly works for others, its core propositions felt irreconcilable with my own experiences. I couldn't, for example, rectify the assertion that "alcoholism is a disease" with the facts of my own life. The idea that by simply attending an AA meeting, without any consultation, one is expected to take on a blanket diagnosis of "diseased addict" was to me, at best, patronizing. At worst, irresponsible. Irresponsible because it doesn't encourage people to turn toward and heal the actual underlying causes of their abuse of substances. I drank for thirteen years for REALLY good reasons. Among them were unprocessed grief, parental abandonment, isolation, violent trauma, anxiety and panic, social oppression, a general lack of safety, deep existential discord, and a tremendous diet and lifestyle imbalance. None of which constitute a disease, and all of which manifest as profound internal, mental, emotional and physical discomfort, which I sought to escape by taking external substances. It is only through one's own efforts to turn toward life on its own terms and to develop a wiser relationship to what's there through mindfulness and compassion that make freedom from addictive patterns possible. My sobriety has been sustained by facing life, processing grief, healing family relationships, accepting radically the fact of social oppression, working with my abandonment conditioning, coming into community, renegotiating trauma, making drastic diet and lifestyle changes, forgiving, and practicing mindfulness, to name just a few. Through these things, I began to relieve the very real pressure that compulsive behaviors are an attempt to resolve.

There is nearly universal consensus that we should prohibit selling and serving alcohol to minors because wine, beer, and spirits can be addictive and, when used to excess, ruinous for their health. Is excess sugar any different?

But my disease grew upon me—for what disease is like Alcohol!

The results of the study were astoundingly clear: The more childhood trauma someone had suffered, the worse their health outcomes were in adulthood. And their risk for contracting diseases didn’t go up just a few percentage points. People with high ACE scores were about three times as likely to develop liver disease, twice as likely to develop cancer or heart disease, four times as likely to develop emphysema.[2] They were seven and a half times more likely to become alcoholics, four and a half times more likely to suffer from depression, and a whopping twelve times more likely to attempt suicide.[3] Scientists have learned that stress is literally toxic. Stress chemicals like cortisol and adrenaline surging through our bodies are healthy in moderation—you wouldn’t be able to get up in the morning without a good dose of cortisol. But in overwhelming quantities, they become toxic and can change the structure of our brains. Stress and depression wear our bodies out. And childhood trauma affects our telomeres. Telomeres are like little caps on the ends of our strands of DNA that keep them from unraveling. As we get older, those telomeres get shorter and shorter. When they’ve finally disappeared, our DNA itself begins to unravel, increasing our chances of getting cancer and making us especially susceptible to disease. Because of this tendency, telomeres are linked to human lifespan. And studies have shown that people who suffered from childhood trauma have significantly shortened telomeres.[4]

One of the cafés had that brilliant idea of putting up a slogan: 'the best protection against infection is a good bottle of wine', which confirmed an already prevalent opinion that alcohol is a safeguard against infectious disease. Every night, towards 2 a.m., quite a number of drunk men, ejected from the cafés , staggered down the streets, vociferating optimism.

One of the cafés had the brilliant idea of putting up a slogan: “The best protection against infection is a bottle of good wine,” which confirmed an already prevalent opinion that alcohol is a safeguard against infectious disease.

Like diabetes, she referred to it. Diabetics take insulin. In the same way, people with bipolar disorders took lithium, and alcoholics went to AA. Diabetes is the all-purpose analogy in my culture. Everybody has some form of it that needs to be tended on a maintenance basis. No one is ever cured, no one gets all the way well.

But, and here comes the rub, all of us feel that we are in complete control of our desire for things. We would never admit to an ungovernable spirit of covetousness. The problem is that we, like the alcoholic, are unable to recognize the disease once we have been engulfed by it. Only by the help of others are we able to detect the inner spirit that places wealth about God. And we must come to fear the idolatrous state of covetousness because the moment things have priority, radical obedience becomes impossible.

Was Trakl a Christian? Yes, of course, at times he becomes a Christian, among a general confusion of becomings—becoming an animal, becoming a virus, becoming inorganic—just as he was also an antichrist, a poet, a pharmacist, an alcoholic, a drug addict, a psychotic, a leper, a suicide, an incestuous cannibal, a necrophiliac, a rodent, a vampire, and a werewolf. Just as he became his sister, and also a hermaphrodite. Trakl's texts are scrawled over by redemptionist monotheism, just as they are stained by narcotic fluidities, gnawed by rats, cratered by Russian artillery, charred and pitted by astronomical debris. Trakl was a Christian and an atheist and also a Satanist, when he wasn't simply undead, or in some other way inhuman. It is perhaps more precise to say that Trakl never existed, except as a battlefield, a reservoir of disease, the graveyard of a deconsecrated church, as something expiring from a massive cocaine overdose on the floor of a military hospital, cheated by lucidity by the searing onslaught of base difference.

Research has shown that the more connected we are socially, the longer we will live and the faster we will recover when we get ill. In truth, isolation and loneliness puts us at a greater risk for early disease and death than smoking. Authentic social connection has a profound effect on your mental health—it even exceeds the value of exercise and ideal body weight on your physical health. It makes you feel good. Social connection triggers the same reward centers in your brain that are triggered when people do drugs, or drink alcohol, or eat chocolate. In other words, we get sick alone, and we get well together.

I’m telling you, the ingenuity of alcoholics is something else. If only it could be put to some kind of good use. I mean, if you said to an alcoholic, ‘Look, the only way for you to get another drink is to cure cancer,’ the disease would be history in five seconds.

Imagine you are a pregnant young woman with tuberculosis. The father of your unborn child is a short-tempered alcoholic with syphilis, a sexually transmitted disease. You have already had five kids. One is blind, another died young, and a third is deaf and unable to speak. The fourth has tuberculosis—the same disease you have. What would you do in this situation? Should you consider abortion? If you chose to have the abortion, you would have ended a valuable human being—regardless of the possible difficulties it may have brought you. Fortunately, the young woman who was really in this dilemma chose life. Otherwise we would never have heard the Fifth Symphony by Beethoven, for this young woman was his mother.

Alcoholism is...an incurable disease. You will have it for life. Just like you can't turn a pickle back into a cucumber.

Alcoholism is the only disease you get yelled at for having

We are powerless over another’s alcoholism. We didn’t cause the disease. We can’t control it. And we can’t cure it.

On the surface a borderline personality can be very difficult to identify, despite the underlying volcanic turbulence. Unlike many people afflicted with other mental disorders—such as schizophrenia, bipolar (manic-depressive) disease, alcoholism, or eating disorders—the borderline can usually function extremely well in work and social situations without appearing overtly pathological. Indeed, some of the hallmarks of borderline behavior are the sudden, unpredictable eruptions of anger, extreme suspiciousness, or suicidal depression from someone who has appeared so “normal.” The

Duck farming is a 24/7 thing. But that's OK, because I'm a caffeine junky. I'm also addicted to cheese. Why does alcoholism get classified as a disease, but I get no sympathy for fiending for brie?

Men are taught over and over when they are boys that a wound that hurts is shameful. A wound that stops you from continuing to play is a girlish wound. He who is truly a man keeps walking, dragging his guts behind. Our story gives a teaching diametrically opposite. It says that where a man's wound is, that is where his genius will be. Wherever the wound appears in our psyches, whether from alcoholic father, shaming mother, shaming father, abusing mother, whether it stems from isolation, disability, or disease, that is precisely the place for which we will give our major gift to the community.

Doing a geographic” is a term alcoholics often use for acting on the impulse to start over by moving to a new town, or state, instead of making any internal changes. It’s the anywhere-but-here part of the disease that says, “Remove yourself from this, go someplace new, and everything will be better.” Two years into our Florida stint, my mother pulled a geographic as radical as the move from Rochester. The new plan was to head for California. She enrolled in the mathematics graduate program at the University of California’s shiny new campus in San Diego, and as soon as our elementary school let out for the summer, she put us into a new Buick station wagon – a gift from her parents – and drove us across the country. You’d think we’d have protested at yet another move. After all, having been duped before, we were in no position to believe that the next move would be any different. But I have no memory of being unhappy about the news. Because that’s what often happens when an alcoholic parent is doing a geographic. She pulls you in and, before you know it, you, too, believe in the promise of the new place.

And yet your shadow isn't following you anymore. At some point your shadow has quietly slipped away. You pretend you don't notice, but you have, you're missing your fucking shadow, though there are plenty of ways to explain it, the angle of the sun, the degree of oblivion induced by the sun beating down on hatless heads, the quantity of alcohol ingested, the movement of something like subterranean tanks of pain, the fear of more contingent things, a disease that begins to become apparent, wounded vanity, the desire just for once in your life to be on time. But the point is, your shadow is lost and you, momentarily, forget it.

Legalism is a more dangerous disease than alcoholism because it doesn’t look like one. Alcoholism makes men fail; legalism helps them succeed in the world. Alcoholism makes men depend on the bottle; legalism makes them self-sufficient, depending on no one. Alcoholism destroys moral resolve; legalism gives it strength. Alcoholics don’t feel welcome in the church; legalists love to hear their morality extolled in church.

You will know if you are too acidic if you get sick often, get urinary tract infections, suffer from headaches, and have bad breath and body odor (when you do not use antiperspirant). Acidosis is the medical term for a blood alkalinity of less than 7.35. A normal reading is called homeostasis. It is not considered a disease; although in and of itself it is recognized as an indicator of disease. Your blood feeds your organs and tissues; so if your blood is acidic, your organs will suffer and your body will have to compensate for this imbalance somehow. We need to do all we can to keep our blood alkalinity high. The way to do this is to dramatically increase our intake of alkaline-rich elements like fresh, clean air; fresh, clean water; raw vegetables (particularly their juices); and sunlight, while drastically reducing our intake of and exposure to acid-forming substances: pollution, cigarettes, hard alcohol, white flour, white sugar, red meat, and coffee. By tipping the scales in the direction of alkalinity through alkaline diet and removal of acid waste through cleansing, and acidic body can become an alkaline one. "Bear in mind that some substances that are alkaline outside the body, like milk, are acidic to the body; meaning that they leave and acid reside in the tissues, just as many substances that are acidic outside the body, like lemons and ripe tomatoes, are alkaline and healing in the body and contribute to the body's critical alkaline reserve.

The pressure to reduce health care costs is aimed only at the treatment of real diseases. There is no pressure to reduce the costs of treating fictitious diseases. On the contrary, there is pressure to define ever more types of undesirable behaviors as mental disorders or addictions and to spend ever more tax dollars on developing new psychiatric diagnoses and facilities for storing and treating the victims of such diseases, whose members now include alcoholics, drug abusers, smokers, overeaters, self-starvers, gamblers, etc.

Alcoholism is a disease of faith. Alcoholics often develop a cynical attitude toward life, not seeing anything to believe in. When you persistently feel the need to change your consciousness through drugs or booze, you are expressing a lack of trust in life itself. And, in some ways, you are expressing a lack of trust in yourself, in your ability to tolerate life undiluted, to find value in your own, unadulterated experience.

Coconut’s distinctive medium-chain composition has been shown to offer protection from heart disease, cancer, diabetes, and many other degenerative illnesses, to improve immune function and fat metabolism, and to protect against liver damage from alcohol and other toxins, and deliver anti-inflammatory and immune-supporting properties.

Alcohol doesn’t benefit anybody except the industry that peddles it. There is no demarcation line between “normal” drinking and problem drinking; it is all part of the same disease. The problem drinker is just at a more advanced stage.

When we attempt to control people and things that we have no business controlling, we are controlled. We forfeit our power to think, feel, and act in accordance with our best interests. We frequently lose control of ourselves. Often, we are being controlled not just by people but by diseases such as alcoholism, eating disorders, and compulsive gambling.

Like alcoholism and drug addiction, nihilism is a disease of the soul. It can never be completely cured, and there is always the possibility of relapse. But there is always a chance for conversion -- a chance for people to believe that there is hope for the future and a meaning to struggle... Nihilism is not overcome by arguments or analyses; it is tamed by love and care.

Depression claims more years than war, cancer, and AIDS put together. Other illnesses, from alcoholism to heart disease, mask depression when it causes them; if one takes that into consideration, depression may be the biggest killer on earth. Treatments

As it happens I am comfortable with the Michael Laskis of this world, with those who live outside rather than in, those in whom the sense of dread is so acute that they turn to extreme and doomed commitments; I know something about dread myself, and appreciate the elaborate systems with which some people manage to fill the void, appreciate all the opiates of the people, whether they are as accessible as alcohol and heroin and promiscuity or as hard to come by as faith in God or History. But of course I did not mention dread to Michael Laski, whose particular opiate is History. I did suggest “depression,” did venture that it might have been “depressing” for him to see only a dozen or so faces at his last May Day demonstration, but he told me that depression was an impediment to the revolutionary process, a disease afflicting only those who do not have ideology to sustain them.

Imagine a person who enjoys alcohol, perhaps a bit too much. He has a quick three or four drinks. His blood alcohol level spikes sharply. This can be extremely exhilarating, particularly for someone who has a genetic predisposition to alcoholism.23 But it only occurs while blood alcohol levels are actively rising, and that only continues if the drinker keeps drinking. When he stops, not only does his blood alcohol level plateau and then start to sink, but his body begins to produce a variety of toxins, as it metabolizes the ethanol already consumed. He also starts to experience alcohol withdrawal, as the anxiety systems that were suppressed during intoxication start to hyper-respond. A hangover is alcohol withdrawal (which quite frequently kills withdrawing alcoholics), and it starts all too soon after drinking ceases. To continue the warm glow, and stave off the unpleasant aftermath, the drinker may just continue to drink, until all the liquor in his house is consumed, the bars are closed and his money is spent. The next day, the drinker wakes up, badly hungover. So far, this is just unfortunate. The real trouble starts when he discovers that his hangover can be “cured” with a few more drinks the morning after. Such a cure is, of course, temporary. It merely pushes the withdrawal symptoms a bit further into the future. But that might be what is required, in the short term, if the misery is sufficiently acute. So now he has learned to drink to cure his hangover. When the medication causes the disease, a positive feedback loop has been established.

Depression can be due to a low endocrine function, nutritional deficiencies, blood sugar problems, food allergies, or systemic yeast infection. Depression can also result from medical illnesses such as stroke, heart attack, cancer, Parkinson's disease, and hormonal disorder. It can also be caused by a serious loss, a difficult relationship, a financial problem, or any stressful, unwelcome life change.

Edgar Allan Poe was an American poet, short story writer, playwright, editor, critic, essayist and one of the leaders of the American Romantic Movement. Best known for his tales of the macabre and mystery, Poe was one of the early American practitioners of the short story and a progenitor of detective fiction and crime fiction. He is also credited with contributing to the emergent science fiction genre.Poe died at the age of 40. The cause of his death is undetermined and has been attributed to alcohol, drugs, cholera, rabies, suicide (although likely to be mistaken with his suicide attempt in the previous year), tuberculosis, heart disease, brain congestion and other agents. Source: Wikipedia

The first time I heard Robert Anda present the results of the ACE study, he could not hold back his tears. In his career at the CDC he had previously worked in several major risk areas, including tobacco research and cardiovascular health. But when the ACE study data started to appear on his computer screen, he realized that they had stumbled upon the gravest and most costly public health issue in the United States: child abuse. He had calculated that its overall costs exceeded those of cancer or heart disease and that eradicating child abuse in America would reduce the overall rate of depression by more than half, alcoholism by two-thirds, and suicide, IV drug use, and domestic violence by three-quarters. 20 It would also have a dramatic effect on workplace performance and vastly decrease the need for incarceration.

Although my work leads me to spend time with Nazi skinheads, diseased street prostitutes and homeless alcoholics, I do not have the strength of character to be a pathologist.

The ceremonial differentiation of the dietary is best seen in the use of intoxicating beverages and narcotics. If these articles of consumption are costly, they are felt to be noble and honorific. Therefore the base classes, primarily the women, practice an enforced continence with respect to these stimulants, except in countries where they are obtainable at a very low cost. From archaic times down through all the length of the patriarchal regime it has been the office of the women to prepare and administer these luxuries, and it has been the perquisite of the men of gentle birth and breeding to consume them. Drunkenness and the other pathological consequences of the free use of stimulants therefore tend in their turn to become honorific, as being a mark, at the second remove, of the superior status of those who are able to afford the indulgence. Infirmities induced by over-indulgence are among some peoples freely recognised as manly attributes. It has even happened that the name for certain diseased conditions of the body arising from such an origin has passed into everyday speech as a synonym for "noble" or "gentle". It is only at a relatively early stage of culture that the symptoms of expensive vice are conventionally accepted as marks of a superior status, and so tend to become virtues and command the deference of the community; but the reputability that attaches to certain expensive vices long retains so much of its force as to appreciably lesson the disapprobation visited upon the men of the wealthy or noble class for any excessive indulgence. The same invidious distinction adds force to the current disapproval of any indulgence of this kind on the part of women, minors, and inferiors. This invidious traditional distinction has not lost its force even among the more advanced peoples of today. Where the example set by the leisure class retains its imperative force in the regulation of the conventionalities, it is observable that the women still in great measure practise the same traditional continence with regard to stimulants.

What I am saying is, alcohol is addictive to everyone. Yet we’ve created a separate disease called alcoholism and forced it upon the minority of the population who are willing to admit they can’t control their drinking, and because of that, we’ve focused on what’s wrong with those few humans rather than on what’s wrong with our alcohol-centric culture or the substance itself.

For the first time I realized that my life was just full of brokenness. I worked in a broken system of justice. My clients were broken by mental illness, poverty, and racism. They were torn apart by disease, drugs and alcohol, pride, fear, and anger. I thought of Joe Sullivan and of Trina, Antonio, Ian, and dozens of other broken children we worked with, struggling to survive in prison. I thought of people broken by war, like Herbert Richardson; people broken by poverty, like Marsha Colbey; people broken by disability, like Avery Jenkins. In their broken state, they were judged and condemned by people whose commitment to fairness had been broken by cynicism, hopelessness, and prejudice.

At the age of fifty he was beginning to discover, with a sense of panic, that his whole life had been in the nature of a hangover, with faintly unpleasant pleasures being atoned for by the dull unalleviated pain of guilt. Had he the solace of knowing that he was an alcoholic, things would have been brighter, because he had read somewhere that alcoholism was a disease; but he was not, he assured himself, alcoholic, only self-indulgent, and his disease, whatever it was, resided in shadier corners of his soul—where decisions were reached not through reason but by rationalization, and where a thin membranous growth of selfishness always seemed to prevent his decent motives from becoming happy actions.

In the United States we are at such a disadvantage because we do not know how to talk about the genocide inflicted on indigenous people. We do not know how to talk about slavery. Otherwise it would not have been assumed that simply because of the election of one Black man to the presidency we would leap forward into a postracial era. We do not acknowledge that we all live on colonized land. And in the meantime, Native Americans live in impoverished conditions on reservations. They have an extremely high incarceration rate—as a matter of fact, per capita the highest incarceration rate—and they suffer disproportionately from such diseases as alcoholism and diabetes. In the meantime, sports teams still mock indigenous people with racially derogatory names, like the Washington Redskins. We do not know how to talk about slavery, except, perhaps, within a framework of victim and victimizer, one that continues to polarize and implicate.

Dear Pighead,   The reason I am so distant is because, well, there are two reasons actually. The first reason is my drinking. I require alcohol, nightly. And nothing can get in the way. The second reason is your disease. I can’t stand the idea of getting close to you, or closer, only to have you up and die on me, pulling the carpet out from under my life. You’re my best friend. The best friend I ever had. I have to protect that. I don’t call you or see you much because I’m killing you off now, while it’s easier. Because I can still talk to you. It makes sense to me to separate now, while you’re still healthy, as opposed to having it just happen to me one night out of the blue. I’m trying to evenly distribute the pain of loss. As opposed to taking it in one lump sum.

Drinking lots of alcohol makes the gut leakier, allowing microbes to more readily influence the brain. Could that help to explain why alcoholics often experience depression or anxiety? Our diet reshapes the microbes in our gut, could those changes ripple out to affect our minds? The gut microbiome becomes less stable in old age-could that contribute to the rise of brain disease in the elderly? And could our microbes manipulate our food cravings in the first place? If you reach for a burger or a chocolate bar what exactly is pushing that hand forward?

Watching a parent die is a terrible task. My father, faced with something he could not talk down or browbeat into submission, spent his days with the bottle, as if he determined to drink himself to death, as if his alcohol could hold back the disease that swept through his brain.

And yet the king and his people did not love McAllister. In truth, they hated him horribly, and, to my knowledge, the whole population, with the priests at the head, tried vainly for three months to pray him to death. The devil-devils they sent after him were awe-inspiring, but since McAllister did not believe in devil-devils, they were without power over him. With drunken Scotchmen all signs fail. They gathered up scraps of food which had touched his lips, an empty whiskey bottle, a cocoanut from which he had drunk, and even his spittle, and performed all kinds of deviltries over them. But McAllister lived on. His health was superb. He never caught fever; nor coughs nor colds; dysentery passed him by; and the malignant ulcers and vile skin diseases that attack blacks and whites alike in that climate never fastened upon him. He must have been so saturated with alcohol as to defy the lodgment of germs. I used to imagine them falling to the ground in showers of microscopic cinders as fast as they entered his whiskey-sodden aura. No one loved him, not even germs, while he loved only whiskey, and still he lived.

Someone once said that the worst features of an era are accented in the children’s books of that period. Book by book our societal problems were dumped into children’s books. What editors called “realism” is really adult betrayal, violence, sexual indiscretions, alcoholism, and the Big D’s: death, divorce, disease, and drugs. Books with inconsequential plots and characters became thinly disguised “moralisms”—the kind of moralisms that come from a nonjudgmental culture urging readers to suspend judgment, to become understanding and noncondemning, and to realize their sexuality.

Work is hazardous to your health, to borrow a book title. In fact, work is mass murder or genocide. Directly or indirectly, work will kill most of the people who read these words... Even if you aren't killed or crippled while actually working, you very well might be while going to work, coming from work, looking for work, or trying to forget about work. The vast majority of victims of the automobile are either doing one of these work-obligatory activities or else fall afoul of those who do them. To this augmented body-count must be added the victims of auto-industrial pollution and work-induced alcoholism and drug addiction. Both cancer and heart disease are modern afflictions normally traceable, directly, or indirectly, to work. Work, then, institutionalizes homicide as a way of life... We kill people in the six-figure range (at least) in order to sell Big Macs and Cadillacs to the survivors. Our forty or fifty thousand annual highway fatalities are victims, not martyrs. They died for nothing -- or rather, they died for work.

Substance abusers lie about everything, and usually do an awesome job of it." Stephen King once wrote. "It's the liar's disease." Nic once told me, quoting an AA platitude, "An alcoholic will steal your wallet and lie about it. A drug addict will steal your wallet and then help you look for it." Part of me is convinced that he actually believes that he will find it for you.

God healed everything in my life from a non-curable disease, bad programming from child sexual abuse, father and mother wounds, bitterness, hatred, rage, rejection, nightmares from the sex industry, sleep disorder, early cervical cancer in 2001, post traumatic stress disorder, alcoholism, mental disorders, and more. God also restored my marriage and relationships with my extended family. Even my mother-in-law loved me now!

nonalcoholic fatty liver disease has become the most common chronic liver disease in the world, increasing from 25 percent of the global population in 1990 to close to 40 percent by 2019. NAFLD is full-blown metabolic dysfunction in kids and adults, representing liver cells filling with fat, which worsens insulin resistance. Key contributors are processed foods, refined sugars, refined grains, sweet beverages, high-fructose corn syrup, fast food, low fiber and phytochemical intake, habitual eating close to bedtime, sedentary behavior, and oxidative stress. Liver transplants have gone up close to 50 percent in the past fifteen years, and while alcohol and hepatitis C used to be the leading causes, now NAFLD is taking the lead in women as the cause of liver failure and is a top cause for men. Fatty liver disease is now the most common cause of liver transplant in young adults in the United States. We are failing our children.

My vocation in life is to wonder about at the nature of the universe. This leads me into philosophy, psychology, religion, and mysticism, not only as subjects to be discussed but also as things to be experienced, and thus I make an at least tacit claim to be a philosopher and a mystic. Some people, therefore, expect me to be their guru or messiah or exemplar, and are extremely disconcerted when they discover my “wayward spirit” or element of irreducible rascality, and say to their friends, “How could he possibly be a genuine mystic and be so addicted to nicotine and alcohol?” Or have occasional shudders of anxiety? Or be sexually interested in women? Or lack enthusiasm for physical exercise? Or have any need for money? Such people have in mind an idealized vision of the mystic as a person wholly free from fear and attachment, who sees within and without, and on all sides, only the translucent forms of a single divine energy which is everlasting love and delight, as which and from which he effortlessly radiates peace, charity, and joy. What an enviable situation! We, too, would like to be one of those, but as we start to meditate and look into ourselves we find mostly a quaking and palpitating mess of anxiety which lusts and loathes, needs love and attention, and lives in terror of death putting an end to its misery. So we despise that mess, and look for ways of controlling it and putting “how the true mystic feels” in its place, not realizing that this ambition is simply one of the lusts of the quaking mess, and that this, in turn, is a natural form of the universe like rain and frost, slugs and snails, flies and disease. When the “true mystic” sees flies and disease as translucent forms of the divine, that does not abolish them. I—making no hard-and-fast distinction between inner and outer experience—see my quaking mess as a form of the divine, and that doesn’t abolish it either. But at least I can live with it.

We continue drinking unchecked, often overlooking the danger of addiction, because we have come to believe alcoholism can only happen to other people. By the time we realize we have a problem, we are faced with self-diagnosing a fatal and incurable illness or admitting to being weak-willed and lacking self-control. We tend to avoid this horrific diagnosis until things have gotten so out of control we can no longer avoid the problem. In some ways this approach has defined alcoholism as a disease of denial.

Control: May 5 Many of us have been trying to keep the whole world in orbit with sheer and forceful application of mental energy. What happens if we let go, if we stop trying to keep the world orbiting and just let it whirl? It’ll keep right on whirling. It’ll stay right on track with no help from us. And we’ll be free and relaxed enough to enjoy our place on it. Control is an illusion, especially the kind of control we’ve been trying to exert. In fact, controlling gives other people, events, and diseases, such as alcoholism, control over us. Whatever we try to control does have control over us and our life. I have given this control to many things and people in my life. I have never gotten the results I wanted from controlling or trying to control people. What I received for my efforts is an unmanageable life, whether that unmanageability was inside me or in external events. In recovery, we make a trade-off. We trade a life that we have tried to control, and we receive in return something better—a life that is manageable. Today, I will exchange a controlled life for one that is manageable.

Neither Xerxes nor Artabanus, therefore, would have passed F. Scott Fitzgerald’s test, from 1936, for a first-rate intelligence: “the ability to hold two opposed ideas in the mind at the same time, and still retain the ability to function.” 21 Fitzgerald may have intended nothing more than a reproach to himself. His writing career had stalled by then, and four years later he would die, of alcoholism, heart disease, and an obscurity made all the more painful by his earlier fame. He was only forty-four. 22 But the cryptic capaciousness of his aphorism, like Berlin’s on foxes and hedgehogs, has made it immortal. The Delphic oracle would have been envious. 23 One possible meaning for Fitzgerald’s opposites could be taking the best from contradictory approaches while rejecting the worst: precisely the compromise that Xerxes and Artabanus failed to reach twenty-four centuries earlier. How, though, might you do that? It’s easy to see how two minds can reach opposite conclusions, but can opposites coexist peacefully within one? They certainly didn’t in Fitzgerald’s, whose life was as tortured as Tolstoy’s, and half the length.

Billions of dollars, trying unsuccessfully to keep drugs out of the world’s most porous border? One-tenth of the anti-drug budget going into education and treatment, nine-tenths of those billions into interdiction? And not enough money from anywhere going into the root causes of the drug problem itself. And the billions spent keeping drug offenders locked up in prison, the cells now so crowded we have to give early release to murderers. Not to mention the fact that two-thirds of all the “non-drug” offenses in America are committed by people high on dope or alcohol. And our solutions are the same futile non-solutions—build more prisons, hire more police, spend more and more billions of dollars not curing the symptoms while we ignore the disease. Most people in my area who want to kick drugs can’t afford to get into a treatment program unless they have blue-chip health insurance, which most of them don’t. And there’s a six-month-to-two-year waiting list to get a bed in a subsidized treatment program. We’re spending almost $2 billion poisoning cocaine crops and kids over here, while there’s no money at home to help someone who wants to get off drugs. It’s insanity.

Originally, the word power meant able to be. In time, it was contracted to mean to be able. We suffer the difference. Iwas waiting for a plane when I overheard two businessmen. One was sharing the good news that he had been promoted, and the other, in congratulation, said, “More power to you.” I've heard this expression before, but for some reason, I heard it differently this time and thought, what a curious sentiment. As a good wish, the assumption is that power is the goal. Of course, it makes a huge difference if we are wishing others worldly power or inner power. By worldly power, I mean power over things, people, and situations—controlling power. By inner power, I mean power that comes from being a part of something larger—connective power. I can't be certain, but I'm fairly sure the wish here was for worldly power, for more control. This is commonplace and disturbing, as the wish for more always issues from a sense of lack. So the wish for more power really issues from a sense of powerlessness. It is painfully ironic that in the land of the free, we so often walk about with an unspoken and enervating lack of personal freedom. Yet the wish for more controlling power will not set us free, anymore than another drink will quench the emptiness of an alcoholic in the grip of his disease. It makes me think of a game we played when I was nine called King of the Hill, in which seven or eight of us found a mound of dirt, the higher the better, and the goal was to stand alone on top of the hill. Once there, everyone else tried to throw you off, installing themselves as King of the Hill. It strikes me now as a training ground for worldly power. Clearly, the worst position of all is being King of the Hill. You are completely alone and paranoid, never able to trust anyone, constantly forced to spin and guard every direction. The hills may change from a job to a woman to a prized piece of real estate, but those on top can be so enslaved by guarding their position that they rarely enjoy the view. I always hated King of the Hill—always felt tense in my gut when king, sad when not, and ostracized if I didn't want to play. That pattern has followed me through life. But now, as a tired adult, when I feel alone and powerless atop whatever small hill I've managed to climb, I secretly long for anyone to join me. Now, I'm ready to believe there's more power here together.

study of thirty thousand elderly people in fifty-two countries found that switching to an overall healthy lifestyle—eating a diet rich in fruits and vegetables, not smoking, exercising moderately, and not drinking too much alcohol—lowered heart disease rates by approximately 50 percent.14 Reducing exposure to carcinogens, such as tobacco and sodium nitrite, have been shown to decrease the incidence of lung and stomach cancers, and it is likely (more evidence is needed) that lowering exposures to other known carcinogens, such as benzene and formaldehyde, will reduce the incidence of other cancers. Prevention really is the most powerful medicine, but we as a species consistently lack the political or psychological will to act preventively in our own best interests. It is worthwhile to ask to what extent efforts to treat the symptoms of common mismatch diseases have the effect of promoting dysevolution by taking attention and resources away from prevention. On an individual level, am I more likely to eat unhealthy foods and exercise insufficiently if I know I’ll have access to medical care to treat the symptoms of the diseases these choices cause many years later? More broadly within our society, is the money we allocate to treating diseases coming at the expense of money to prevent them?

I'm going to throw some suggestions at you now in rapid succession, assuming you are a father of one or more boys. Here we go: If you speak disparagingly of the opposite sex, or if you refer to females as sex objects, those attitudes will translate directly into dating and marital relationships later on. Remember that your goal is to prepare a boy to lead a family when he's grown and to show him how to earn the respect of those he serves. Tell him it is great to laugh and have fun with his friends, but advise him not to be "goofy." Guys who are goofy are not respected, and people, especially girls and women, do not follow boys and men whom they disrespect. Also, tell your son that he is never to hit a girl under any circumstances. Remind him that she is not as strong as he is and that she is deserving of his respect. Not only should he not hurt her, but he should protect her if she is threatened. When he is strolling along with a girl on the street, he should walk on the outside, nearer the cars. That is symbolic of his responsibility to take care of her. When he is on a date, he should pay for her food and entertainment. Also (and this is simply my opinion), girls should not call boys on the telephone-at least not until a committed relationship has developed. Guys must be the initiators, planning the dates and asking for the girl's company. Teach your son to open doors for girls and to help them with their coats or their chairs in a restaurant. When a guy goes to her house to pick up his date, tell him to get out of the car and knock on the door. Never honk. Teach him to stand, in formal situations, when a woman leaves the room or a table or when she returns. This is a way of showing respect for her. If he treats her like a lady, she will treat him like a man. It's a great plan. Make a concerted effort to teach sexual abstinence to your teenagers, just as you teach them to abstain from drug and alcohol usage and other harmful behavior. Of course you can do it! Young people are fully capable of understanding that irresponsible sex is not in their best interest and that it leads to disease, unwanted pregnancy, rejection, etc. In many cases today, no one is sharing this truth with teenagers. Parents are embarrassed to talk about sex, and, it disturbs me to say, churches are often unwilling to address the issue. That creates a vacuum into which liberal sex counselors have intruded to say, "We know you're going to have sex anyway, so why not do it right?" What a damning message that is. It is why herpes and other sexually transmitted diseases are spreading exponentially through the population and why unwanted pregnancies stalk school campuses. Despite these terrible social consequences, very little support is provided even for young people who are desperately looking for a valid reason to say no. They're told that "safe sex" is fine if they just use the right equipment. You as a father must counterbalance those messages at home. Tell your sons that there is no safety-no place to hide-when one lives in contradiction to the laws of God! Remind them repeatedly and emphatically of the biblical teaching about sexual immorality-and why someone who violates those laws not only hurts himself, but also wounds the girl and cheats the man she will eventually marry. Tell them not to take anything that doesn't belong to them-especially the moral purity of a woman.

no matter how you look at the issue, prevention is a fundamentally preferable and more cost-effective way to promote health and longevity. Most people agree that we invest insufficiently in prevention, but they would also surmise that it is difficult to get young, healthy people to avoid behaviors that increase their risk of future illness. Consider smoking, which causes more preventable deaths than any major risk factor (the other big ones being physical inactivity, poor diet, and alcohol abuse). After prolonged legal battles, public health efforts to discourage smoking have managed to halve the percentage of Americans who smoke since the 1950s.19 Yet 20 percent of Americans still smoke, causing 443,000 premature deaths in 2011 at a direct cost of $96 billion per year. Likewise, most Americans know they should be physically active and eat a healthy diet, yet only 20 percent of Americans meet the government’s recommendations for physical activity, and fewer than 20 percent meet government dietary guidelines.20 There are many, diverse reasons we are bad at persuading, nudging, or otherwise encouraging people to use their bodies more as they evolved to be used (more on this later), but one contributing factor could be that we are still following in the footsteps of the marquis de Condorcet, waiting for the next promised breakthrough. Scared of death and hopeful about science, we spend billions of dollars trying to figure out how to regrow diseased organs, hunting for new drugs, and designing artifical body parts to replace the ones we wear out. I am in no way suggesting that we cease investing in these and other areas. Quite the contrary: let’s spend more! But let’s not do so in a way that promotes the pernicious feedback loop of just treating mismatch diseases rather than preventing them. In practical

Perfectionists are working not to improve the world but to keep it under control. They do everything perfectly not for the satisfaction of a job well done but as a way of camouflaging addiction’s presence in the family. By keeping everything orderly, they’re trying to make the disease less noticeable. They work tirelessly to create a perfect family life but are rarely cognizant of what motivates their obsession. Through their eyes, perfectionism is their finest quality. It’s the way they provide the ones they love with the very best. They have no idea that perfectionism is an outgrowth of fear and that it’s more about looking happy than being happy. The compulsion to have the cleanest house, cook the best meals, plant the perfect garden, and always look perfectly coiffed is, for the perfectionist, a way to stay safe. After all, when the house is well kept, the children are properly dressed, and everyone has good manners, how can

The strongest evidence yet was published in 2010. In a painstaking long-term study, much larger and more thorough than anything done previously, an international team of researchers tracked one thousand children in New Zealand from birth until the age of thirty-two. Each child’s self-control was rated in a variety of ways (through observations by researchers as well as in reports of problems from parents, teachers, and the children themselves). This produced an especially reliable measure of children’s self-control, and the researchers were able to check it against an extraordinarily wide array of outcomes through adolescence and into adulthood. The children with high self-control grew up into adults who had better physical health, including lower rates of obesity, fewer sexually transmitted diseases, and even healthier teeth. (Apparently, good self-control includes brushing and flossing.) Self-control was irrelevant to adult depression, but its lack made people more prone to alcohol and drug problems. The children with poor self-control tended to wind up poorer financially. They worked in relatively low-paying jobs, had little money in the bank, and were less likely to own a home or have money set aside for retirement. They also grew up to have more children being raised in single-parent households, presumably because they had a harder time adapting to the discipline required for a long-term relationship. The children with good self-control were much more likely to wind up in a stable marriage and raise children in a two-parent home. Last, but certainly not least, the children with poor self-control were more likely to end up in prison. Among those with the lowest levels of self-control, more than 40 percent had a criminal conviction by the age of thirty-two, compared with just 12 percent of the people who had been toward the high end of the self-control distribution in their youth.

Between 1995 and 1997 the California-based healthcare network Kaiser Permanente gave more than 17,000 patients a questionnaire to assess the level of trauma in their childhoods. Questions included whether the patients' parents had been mentally or physically abusive or neglectful and whether their parents were divorced or had abused substances. This was called the Adverse Childhood Experiences (ACE) study. After taking the questionnaire, patients were given an ACE score on a scale of 0 to 10. The higher the score, the more trauma a person experienced in childhood. The results of the study were astoundingly clear: The more childhood trauma someone had suffered, the worse their health outcomes were in adulthood. And their risk for contracting diseases didn't go up just a few percentage points. People with high ACE scores were about three times as likely to develop liver disease, twice as likely to develop cancer or heart disease, four times as likely to develop emphysema. They were seven and a half times more likely to become alcoholics, four and a half times more likely to suffer from depression, and a whopping twelve times more likely to attempt suicide. Scientists have learned that stress is literally toxic. Stress chemicals surging through our bodies like cortisol and adrenaline are healthy in moderation—you wouldn't be able to get up in the morning without a good dose of cortisol. But in overwhelming quantities, they become toxic and can change the structure of our brains. Stress and depression wear our bodies out. And childhood trauma affects our telomeres. Telomeres are like little caps on the ends of our strands of DNA that keep them from unraveling. As we get older, those telomeres get shorter and shorter. When they've finally disappeared, our DNA itself begins to unravel, increasing our chances of getting cancer and making us especially susceptible to disease. Because of this, telomeres are linked to human lifespan. And studies have shown that people who have suffered from childhood trauma have significantly shortened telomeres. In the end, these studies claimed that having an ACE score of 6 or higher takes twenty years off your life expectancy. The average life expectancy for someone with 6 or more ACEs is sixty years old.

tried to go to a counselor, but it was just too weird. Talking to some stranger about my feelings made me want to vomit. I did go to the library, and I learned that behavior I considered commonplace was the subject of pretty intense academic study. Psychologists call the everyday occurrences of my and Lindsay’s life “adverse childhood experiences,” or ACEs. ACEs are traumatic childhood events, and their consequences reach far into adulthood. The trauma need not be physical. The following events or feelings are some of the most common ACEs: •​being sworn at, insulted, or humiliated by parents •​being pushed, grabbed, or having something thrown at you •​feeling that your family didn’t support each other •​having parents who were separated or divorced •​living with an alcoholic or a drug user •​living with someone who was depressed or attempted suicide •​watching a loved one be physically abused. ACEs happen everywhere, in every community. But studies have shown that ACEs are far more common in my corner of the demographic world. A report by the Wisconsin Children’s Trust Fund showed that among those with a college degree or more (the non–working class), fewer than half had experienced an ACE. Among the working class, well over half had at least one ACE, while about 40 percent had multiple ACEs. This is really striking—four in every ten working-class people had faced multiple instances of childhood trauma. For the non–working class, that number was 29 percent. I gave a quiz to Aunt Wee, Uncle Dan, Lindsay, and Usha that psychologists use to measure the number of ACEs a person has faced. Aunt Wee scored a seven—higher even than Lindsay and me, who each scored a six. Dan and Usha—the two people whose families seemed nice to the point of oddity—each scored a zero. The weird people were the ones who hadn’t faced any childhood trauma. Children with multiple ACEs are more likely to struggle with anxiety and depression, to suffer from heart disease and obesity, and to contract certain types of cancers. They’re also more likely to underperform in school and suffer from relationship instability as adults. Even excessive shouting can damage a kid’s sense of security and contribute to mental health and behavioral issues down the road. Harvard pediatricians have studied the effect that childhood trauma has on the mind. In addition to later negative

The clinical hallmark of manic-depressive illness is its recurrent, episodic nature. Byron had this in an almost textbook manner, showing frequent and pronounced fluctuations in mood, energy, sleep patterns, sexual behavior, alcohol and other drug use, and weight (Byron also exhibited extremes in dieting, obsession with his weight, eccentric eating patterns, and excessive use of epsom salts). Although these changes in mood and behavior were dramatic and disruptive when they occurred, it is important to note that Byron was clinically normal most of the time; this, too, is highly characteristic of manic-depressive illness. An inordinate amount of confusion about whether someone does or does not have manic-depressive illness stems from the popular misconception that irrationality of mood and reason are stable rather than fluctuating features of the disease. Some assume that because an individual such as Byron was sane and in impressive control of his reason most of the time, that he could not have been "mad" or have suffered from a major mental illness. Lucidity and normal functioning are, however, perfectly consistent with-indeed, characteristic of-the phasic nature of manic-depressive illness. This is in contrast to schizophrenia, which is usually a chronic and relatively unrelenting illness characterized by, among other things, an inability to reason clearly.

Outlawing drugs in order to solve drug problems is much like outlawing sex in order to win the war against AIDS. We recognize that people will continue to have sex for nonreproductive reasons despite the laws and mores. Therefore, we try to make sexual practices as safe as possible in order to minimize the spread of the AIDS viruses. In a similar way, we continually try to make our drinking water, foods, and even our pharmaceutical medicines safer. The ubiquity of chemical intoxicants in our lives is undeniable evidence of the continuing universal need for safer medicines with such applications. While use may not always be for an approved medical purpose, or prudent, or even legal, it is fulfilling the relentless drive we all have to change the way we feel, to alter our behavior and consciousness, and, yes, to intoxicate ourselves. We must recognize that intoxicants are medicines, treatments for the human condition. Then we must make them as safe and risk free and as healthy as possible. Dream with me for a moment. What would be wrong if we had perfectly safe intoxicants? I mean drugs that delivered the same effects as our most popular ones but never caused dependency, disease, dysfunction, or death. Imagine an alcohol-type substance that never caused addiction, liver disease, hangovers, impaired driving, or workplace problems. Would you care to inhale a perfumed mist that is as enjoyable as marijuana or tobacco but as harmless as clean air? How would you like a pain-killer as effective as morphine but safer than aspirin, a mood enhancer that dissolves on your tongue and is more appealing than cocaine and less harmful than caffeine, a tranquilizer less addicting than Valium and more relaxing than a martini, or a safe sleeping pill that allows you to choose to dream or not? Perhaps you would like to munch on a user friendly hallucinogen that is as brief and benign as a good movie? This is not science fiction. As described in the following pages, there are such intoxicants available right now that are far safer than the ones we currently use. If smokers can switch from tobacco cigarettes to nicotine gum, why can’t crack users chew a cocaine gum that has already been tested on animals and found to be relatively safe? Even safer substances may be just around the corner. But we must begin by recognizing that there is a legitimate place in our society for intoxication. Then we must join together in building new, perfectly safe intoxicants for a world that will be ready to discard the old ones like the junk they really are. This book is your guide to that future. It is a field guide to that silent spring of intoxicants and all the animals and peoples who have sipped its waters. We can no more stop the flow than we can prevent ourselves from drinking. But, by cleaning up the waters we can leave the morass that has been the endless war on drugs and step onto the shores of a healthy tomorrow. Use this book to find the way.

Hunter-gatherers who survive childhood typically live to be old: their most common age of death is between sixty-eight and seventy-two, and most become grandparents or even great-grandparents.70 They most likely die from gastrointestinal or respiratory infections, diseases such as malaria or tuberculosis, or from violence and accidents.71 Health surveys also indicate that most of the noninfectious diseases that kill or disable older people in developed nations are rare or unknown among middle-aged and elderly hunter-gatherers.72 These admittedly limited studies have found that hunter-gatherers rarely if ever get type 2 diabetes, coronary heart disease, hypertension, osteoporosis, breast cancer, asthma, and liver disease. They also don’t appear to suffer much from gout, myopia, cavities, hearing loss, collapsed arches, and other common ailments. To be sure, hunter-gatherers don’t live in perpetually perfect health, especially since tobacco and alcohol have become increasingly available to them, but the evidence suggests that they are healthy compared to many older Americans today despite never having received any medical care. In short, if you were to compare contemporary health data from people around the world with equivalent data from hunter-gatherers, you would not conclude that rising rates of common mismatch diseases such as heart disease and type 2 diabetes are straightforward, inevitable by-products of economic progress and increased longevity. Moreover,

Here’s how I’ve always pictured mitigated free will: There’s the brain—neurons, synapses, neurotransmitters, receptors, brainspecific transcription factors, epigenetic effects, gene transpositions during neurogenesis. Aspects of brain function can be influenced by someone’s prenatal environment, genes, and hormones, whether their parents were authoritative or their culture egalitarian, whether they witnessed violence in childhood, when they had breakfast. It’s the whole shebang, all of this book. And then, separate from that, in a concrete bunker tucked away in the brain, sits a little man (or woman, or agendered individual), a homunculus at a control panel. The homunculus is made of a mixture of nanochips, old vacuum tubes, crinkly ancient parchment, stalactites of your mother’s admonishing voice, streaks of brimstone, rivets made out of gumption. In other words, not squishy biological brain yuck. And the homunculus sits there controlling behavior. There are some things outside its purview—seizures blow the homunculus’s fuses, requiring it to reboot the system and check for damaged files. Same with alcohol, Alzheimer’s disease, a severed spinal cord, hypoglycemic shock. There are domains where the homunculus and that brain biology stuff have worked out a détente—for example, biology is usually automatically regulating your respiration, unless you must take a deep breath before singing an aria, in which case the homunculus briefly overrides the automatic pilot. But other than that, the homunculus makes decisions. Sure, it takes careful note of all the inputs and information from the brain, checks your hormone levels, skims the neurobiology journals, takes it all under advisement, and then, after reflecting and deliberating, decides what you do. A homunculus in your brain, but not of it, operating independently of the material rules of the universe that constitute modern science. That’s what mitigated free will is about. I see incredibly smart people recoil from this and attempt to argue against the extremity of this picture rather than accept its basic validity: “You’re setting up a straw homunculus, suggesting that I think that other than the likes of seizures or brain injuries, we are making all our decisions freely. No, no, my free will is much softer and lurks around the edges of biology, like when I freely decide which socks to wear.” But the frequency or significance with which free will exerts itself doesn’t matter. Even if 99.99 percent of your actions are biologically determined (in the broadest sense of this book), and it is only once a decade that you claim to have chosen out of “free will” to floss your teeth from left to right instead of the reverse, you’ve tacitly invoked a homunculus operating outside the rules of science. This is how most people accommodate the supposed coexistence of free will and biological influences on behavior. For them, nearly all discussions come down to figuring what our putative homunculus should and shouldn’t be expected to be capable of.

Every so often, the gods stop laughing long enough to do something terrible. There are few facts that are not brutal. The bitter, insufficient truth is that God recovered, but fun is dead. Alcohol: the antidote to civilization. Alcoholism is a fatal disease. But then I am not a member of Alcoholics Anonymous, because I don't want to be cured. Alcoholism is suicide with training wheels. I watch myself sinking, an inch at a time, and I spit into the eye of fate, like Doc Holliday, who died too weak to lift a playing card. My traitorous and degenerate attitude is sort of my book review of the world we live in. I resign from the human race. I declare myself null and void; folded, spindled, and mutilated. . . .This bar is an oasis for the night people, the street people, the invisible tribe, the people who simply do not exist in the orderly world we see in Time - the weekly science fiction magazine published by the Pentagon - an orderly world which is a sanitized Emerald City populated by contented Munchkins who pay taxes to buy tanks, nerve gas, and bombers and not a world which is a bus-station toilet where the air is a chemical cocktail of cancer-causing agents, children are starving, and the daily agenda is kill or be killed. When the world demands that you be larger than life, and you are finding it hard enough just being life-size, you can come here, in the messy hemorrhaging of reality, let your hair down, take your girdle off, and not be embarrassed by your wounds and deformities. Here among the terminally disenchanted you are graded not by the size of the car on display in your driveway but by the size of your courage in the face of nameless things. . . .Half of these people look like they just came back from the moon, and all of them are sworn witnesses for the prosecution on the charge that Earth serves as Hell for some other planet.

What, then, is addiction? In the words of a consensus statement by addiction experts in 2001, addiction is a “chronic neurobiological disease… characterized by behaviors that include one or more of the following: impaired control over drug use, compulsive use, continued use despite harm, and craving.” The key features of substance addiction are the use of drugs or alcohol despite negative consequences, and relapse. I’ve heard some people shrug off their addictive tendencies by saying, for example, “I can’t be an alcoholic. I don’t drink that much…” or “I only drink at certain times.” The issue is not the quantity or even the frequency, but the impact. “An addict continues to use a drug when evidence strongly demonstrates the drug is doing significant harm…. If users show the pattern of preoccupation and compulsive use repeatedly over time with relapse, addiction can be identified.” Helpful as such definitions are, we have to take a broader view to understand addiction fully. There is a fundamental addiction process that can express itself in many ways, through many different habits. The use of substances like heroin, cocaine, nicotine and alcohol are only the most obvious examples, the most laden with the risk of physiological and medical consequences. Many behavioural, nonsubstance addictions can also be highly destructive to physical health, psychological balance, and personal and social relationships. Addiction is any repeated behaviour, substance-related or not, in which a person feels compelled to persist, regardless of its negative impact on his life and the lives of others. Addiction involves: 1. compulsive engagement with the behaviour, a preoccupation with it; 2. impaired control over the behaviour; 3. persistence or relapse, despite evidence of harm; and 4. dissatisfaction, irritability or intense craving when the object — be it a drug, activity or other goal — is not immediately available. Compulsion, impaired control, persistence, irritability, relapse and craving — these are the hallmarks of addiction — any addiction. Not all harmful compulsions are addictions, though: an obsessive-compulsive, for example, also has impaired control and persists in a ritualized and psychologically debilitating behaviour such as, say, repeated hand washing. The difference is that he has no craving for it and, unlike the addict, he gets no kick out of his compulsion. How does the addict know she has impaired control? Because she doesn’t stop the behaviour in spite of its ill effects. She makes promises to herself or others to quit, but despite pain, peril and promises, she keeps relapsing. There are exceptions, of course. Some addicts never recognize the harm their behaviours cause and never form resolutions to end them. They stay in denial and rationalization. Others openly accept the risk, resolving to live and die “my way.