Systems Biology Quotes

And as humans, we’re by-products of our upbringings, victims of our lackluster educational systems, and choosers of our behaviors. In short, the reduction of women to something less than men, and the elevation of men to something more than women, is not biological: it’s cultural. And it starts with two words: pink and blue. Everything skyrockets out of control from there.” Speaking

We’re so self-important. Everybody’s going to save something now. “Save the trees, save the bees, save the whales, save those snails.” And the greatest arrogance of all: save the planet. Save the planet, we don’t even know how to take care of ourselves yet. I’m tired of this shit. I’m tired of f-ing Earth Day. I’m tired of these self-righteous environmentalists, these white, bourgeois liberals who think the only thing wrong with this country is that there aren’t enough bicycle paths. People trying to make the world safe for Volvos. Besides, environmentalists don’t give a shit about the planet. Not in the abstract they don’t. You know what they’re interested in? A clean place to live. Their own habitat. They’re worried that some day in the future they might be personally inconvenienced. Narrow, unenlightened self-interest doesn’t impress me. The planet has been through a lot worse than us. Been through earthquakes, volcanoes, plate tectonics, continental drift, solar flares, sun spots, magnetic storms, the magnetic reversal of the poles … hundreds of thousands of years of bombardment by comets and asteroids and meteors, worldwide floods, tidal waves, worldwide fires, erosion, cosmic rays, recurring ice ages … And we think some plastic bags and some aluminum cans are going to make a difference? The planet isn’t going anywhere. WE are! We’re going away. Pack your shit, folks. We’re going away. And we won’t leave much of a trace, either. Maybe a little Styrofoam … The planet’ll be here and we’ll be long gone. Just another failed mutation. Just another closed-end biological mistake. An evolutionary cul-de-sac. The planet’ll shake us off like a bad case of fleas. The planet will be here for a long, long, LONG time after we’re gone, and it will heal itself, it will cleanse itself, ’cause that’s what it does. It’s a self-correcting system. The air and the water will recover, the earth will be renewed. And if it’s true that plastic is not degradable, well, the planet will simply incorporate plastic into a new paradigm: the earth plus plastic. The earth doesn’t share our prejudice toward plastic. Plastic came out of the earth. The earth probably sees plastic as just another one of its children. Could be the only reason the earth allowed us to be spawned from it in the first place. It wanted plastic for itself. Didn’t know how to make it. Needed us. Could be the answer to our age-old egocentric philosophical question, “Why are we here?” Plastic… asshole.

The way fungi and mycorrhizae direct nutrients in biological ecosystems is a case study for how we can direct resources within human economic systems. And in doing this, we cultivate a multitude of business opportunities.

The fundamental claim of intelligent design is straightforward and easily intelligible: namely, there are natural systems that cannot be adequately explained in terms of undirected natural forces and that exhibit features which in any other circumstance we would attribute to intelligence.

In response to threat and injury, animals, including humans, execute biologically based, non-conscious action patterns that prepare them to meet the threat and defend themselves. The very structure of trauma, including activation, dissociation and freezing are based on the evolution of survival behaviors. When threatened or injured, all animals draw from a "library" of possible responses. We orient, dodge, duck, stiffen, brace, retract, fight, flee, freeze, collapse, etc. All of these coordinated responses are somatically based- they are things that the body does to protect and defend itself. It is when these orienting and defending responses are overwhelmed that we see trauma. The bodies of traumatized people portray "snapshots" of their unsuccessful attempts to defend themselves in the face of threat and injury. Trauma is a highly activated incomplete biological response to threat, frozen in time. For example, when we prepare to fight or to flee, muscles throughout our entire body are tensed in specific patterns of high energy readiness. When we are unable to complete the appropriate actions, we fail to discharge the tremendous energy generated by our survival preparations. This energy becomes fixed in specific patterns of neuromuscular readiness. The person then stays in a state of acute and then chronic arousal and dysfunction in the central nervous system. Traumatized people are not suffering from a disease in the normal sense of the word- they have become stuck in an aroused state. It is difficult if not impossible to function normally under these circumstances.

The conclusion of intelligent design flows naturally from the data itself—not from sacred books or sectarian beliefs. Inferring that biochemical systems were designed by an intelligent agent is a humdrum process that requires no new principles of logic or science. It comes simply from the hard work that biochemistry has done over the past forty years, combined with consideration of the way in which we reach conclusions of design every day.

When emotions are expressed...all systems are united and made whole. When emotions are repressed, denied, not allowed to be whatever they may be, our network pathways get blocked, stopping the flow of the vital feel-good, unifying chemicals that run both our biology and our behavior.

[R]eligion was the race's first (and worst) attempt to make sense of reality. It was the best the species could do at a time when we had no concept of physics, chemistry, biology or medicine. We did not know that we lived on a round planet, let alone that the said planet was in orbit in a minor and obscure solar system, which was also on the edge of an unimaginably vast cosmos that was exploding away from its original source of energy. We did not know that micro-organisms were so powerful and lived in our digestive systems in order to enable us to live, as well as mounting lethal attacks on us as parasites. We did not know of our close kinship with other animals. We believed that sprites, imps, demons, and djinns were hovering in the air about us. We imagined that thunder and lightning were portentous. It has taken us a long time to shrug off this heavy coat of ignorance and fear, and every time we do there are self-interested forces who want to compel us to put it back on again.

Stephen Hawking said that his quest is simply "trying to understand the mind of God".

Creatures from another world, only statues when you see them. Lonely Assassins, that's what they used to be called. No one quite knows where they came from, but they're as old as the Universe, or very nearly. And they have survived this long because they have the most perfect defence system ever evolved. They are Quantum Locked. They don't exist when they are being observed. The moment they are seen by any other living creature they freeze into rock. No choice, it's a fact of their biology. In the sight of any living thing, they literally turn into stone. And you can't kill a stone. Of course, a stone can't kill you either, but then you turn your head away. Then you blink. Then, oh yes, it can. That's why they cover their eyes. They're not weeping, they can't risk looking at each other. Their greatest asset is their greatest curse. They can never be seen. Loneliest creatures in the Universe. And I'm sorry. I am very, very sorry. It's up to you now. Don't blink. Don't even blink. Blink and you're dead. They are fast. Faster than you can believe. Don't turn your back, don't look away, and DON'T blink. Good luck.

The brief span of an individual life is misleading. Each one of us is as old as the entire biological kingdom, and our bloodstreams are tributaries of the great sea of its total memory. The uterine odyssey of the growing foetus recapitulates the entire evolutionary past, and its central nervous system is a coded time scale, each nexus of neurones and each spinal level marking a symbolic station, a unit of neuronic time.

To make biological survival possible, Mind at Large has to be funnelled through the reducing valve of the brain and nervous system. What comes out at the other end is a measly trickle of the kind of consciousness which will help us to stay alive on the surface of this particular planet. To formulate and express the contents of this reduced awareness, man has invented and endlessly elaborated those symbol-systems and implicit philosophies which we call languages. Every individual is at once the beneficiary and the victim of the linguistic tradition into which he or she has been born -- the beneficiary inasmuch as language gives access to he accumulated records of other people's experience, the victim in so far as it confirms him in the belief that reduced awareness is the only awareness and as it be-devils his sense of reality, so that he is all too apt to take his concepts for data, his words for actual things.

Molecular biology has shown that even the simplest of all living systems on the earth today, bacterial cells, are exceedingly complex objects. Although the tiniest bacterial cells are incredibly small, weighing less than 10-12 gms, each is in effect a veritable micro-miniaturized factory containing thousands of exquisitely designed pieces of intricate molecular machinery, made up altogether of one hundred thousand million atoms, far more complicated than any machine built by man and absolutely without parallel in the nonliving world.

Once the cells in a biological machine stop working, it can never be started again. It goes into a cascade of decay, falling toward disorder and randomness. Except in the case of viruses. They can turn off and go dead. Then, if they come in contact with a living system, they switch on and multiply. (194)

Humanity has in the course of time had to endure from the hands of science two great outrages upon its naive self-love. The first was when it realized that our earth was not the center of the universe, but only a tiny speck in a world-system of a magnitude hardly conceivable; this is associated in our minds with the name of Copernicus, although Alexandrian doctrines taught something very similar. The second was when biological research robbed man of his peculiar privilege of having been specially created, and relegated him to a descent from the animal world, implying an ineradicable animal nature in him: this transvaluation has been accomplished in our own time upon the instigation of Charles Darwin, Wallace, and their predecessors, and not without the most violent opposition from their contemporaries. But man's craving for grandiosity is now suffering the third and most bitter blow from present-day psychological research which is endeavoring to prove to the ego of each one of us that he is not even master in his own house, but that he must remain content with the veriest scraps of information about what is going on unconsciously in his own mind. We psycho-analysts were neither the first nor the only ones to propose to mankind that they should look inward; but it appears to be our lot to advocate it most insistently and to support it by empirical evidence which touches every man closely.

Random mutations much more easily debilitate genes than improve them, and that this is true even of the helpful mutations. Let me emphasize, our experience with malaria’s effects on humans (arguably our most highly studied genetic system) shows that most helpful mutations degrade genes. What’s more, as a group the mutations are incoherent, meaning that they are not adding up to some new system. They are just small changes - mostly degradative - in pre-existing, unrelated genes. The take-home lesson is that this is certainly not the kind of process we would expect to build the astonishingly elegant machinery of the cell. If random mutation plus selective pressure substantially trashes the human genome, why should we think that it would be a constructive force in the long term? There is no reason to think so.

In fact, biology is chaos. Biological systems are the product not of logic but of evolution, an inelegant process. Life does not choose the logically best design to meet a new situation. It adapts what already exists...The result, unlike the clean straight lines of logic, is often irregular, messy.

‎What color is a chameleon placed on a mirror? ... The chameleon responding to its own shifting image is an apt analog of the human world of fashion. Taken as a whole, what are fads but the response of a hive mind to its own reflection? In a 21st-century society wired into instantaneous networks, marketing is the mirror; the collective consumer is the chameleon.

The same way biodiversity is important to biological ecosystems, business diversity is important to economic ecosystems. It's good to have an abundance of various kinds of businesses. This cultivates resilience in the system.

(Evolution) general condition to which all theories, all hypotheses, all systems must bow and which they must satisfy henceforward if they are to be thinkable and true. Evolution is a light which illuminates all facts, a curve that all lines must follow.

Companies can learn a lot from biological systems. The human immune system for example is adaptive, redundant, diverse, modular, data-driven and network collaborative. A company that desires not just short term profit but also long term resilience should apply these features of the human immune system to it's business models and company structure.

having freed ourselves from the constraints of evolution, humans nevertheless remain dependent on the earth’s biological and geochemical systems. By disrupting these systems—cutting down tropical rainforests, altering the composition of the atmosphere, acidifying the oceans—we’re putting our own survival in danger.

She wanted to tell the girl: It’s complicated. I am now a person I never imagined I would be, and I don’t know how to square that. I would like to be content, but instead I am stuck inside a prison of my own creation, where I torment myself endlessly, until I am left binge-eating Fig Newtons at midnight to keep from crying. I feel as though societal norms, gendered expectations, and the infuriating bluntness of biology have forced me to become this person even though I’m having a hard time parsing how, precisely, I arrived at this place. I am angry all the time. I would one day like to direct my own artwork toward a critique of these modern-day systems that articulates all this, but my brain no longer functions as it did before the baby, and I am really dumb now. I am afraid I will never be smart or happy or thin again. I am afraid I might be turning into a dog. Instead, she said, smiling, I love it. I love being a mom.

Business leaders a hundred years ago thought about business with a very mechanical way of thinking. But today and going forward, business leaders need to think about business with a biological and energetic way of thinking; thinking of business in terms of living systems.

The most essential prediction of Darwinism is that, given an astronomical number of chances, unintelligent processes can make seemingly-designed systems, ones of the complexity of those found in the cell. ID specifically denies this, predicting that in the absence of intelligent input no such systems would develop. So Darwinism and ID make clear, opposite predictions of what we should find when we examine genetic results from a stupendous number of organisms that are under relentless pressure from natural selection. The recent genetic results are a stringent test. The results: 1) Darwinism’s prediction is falsified; 2) Design’s prediction is confirmed.

I am not my opinion of myself, I am not anything I can describe to me. I am only a part of a large system that cannot describe itself fully; therefore, I relax and I am in the point source of consciousness, of delight, of mobility, in the inner spaces. My tasks do not include describing me nor having an opinion about the system in which I live, biological or social or dyadic. I hereby drop that "responsibility". I am much more than I can conceive or judge me to be. Any negative or positive opinions I have of me are false fronts, headlines, limited and unnecessary programmes written on a thin paper blowing about and floating around in the vastness of inner spaces.

Second, nothing about adolescence can be understood outside the context of delayed frontocortical maturation. If by adolescence limbic, autonomic, and endocrine systems are going full blast while the frontal cortex is still working out the assembly instructions, we’ve just explained why adolescents are so frustrating, great, asinine, impulsive, inspiring, destructive, self-destructive, selfless, selfish, impossible, and world changing. Think about this—adolescence and early adulthood are the times when someone is most likely to kill, be killed, leave home forever, invent an art form, help overthrow a dictator, ethnically cleanse a village, devote themselves to the needy, become addicted, marry outside their group, transform physics, have hideous fashion taste, break their neck recreationally, commit their life to God, mug an old lady, or be convinced that all of history has converged to make this moment the most consequential, the most fraught with peril and promise, the most demanding that they get involved and make a difference. In other words, it’s the time of life of maximal risk taking, novelty seeking, and affiliation with peers. All because of that immature frontal cortex.

If biologists have ignored self-organization, it is not because self-ordering is not pervasive and profound. It is because we biologists have yet to understand how to think about systems governed simultaneously by two sources of order, Yet who seeing the snowflake, who seeing simple lipid molecules cast adrift in water forming themselves into cell-like hollow lipid vesicles, who seeing the potential for the crystallization of life in swarms of reacting molecules, who seeing the stunning order for free in networks linking tens upon tens of thousands of variables, can fail to entertain a central thought: if ever we are to attain a final theory in biology, we will surely, surely have to understand the commingling of self-organization and selection. We will have to see that we are the natural expressions of a deeper order. Ultimately, we will discover in our creation myth that we are expected after all.

Hierarchical organization in biological systems thus is characterized by an exquisite array of delicately and intricately interlocked order, steadily increasing in level and complexity and thereby giving rise neogenetically to emergent properties.

No civilization can possibly survive to an interstellar spacefaring phase unless it limits its numbers. Any society with a marked population explosion will be forced to devote all its energies and technological skills to feeding and caring for the population on its home planet. This is a very powerful conclusion and is in no way based on the idiosyncrasies of a particular civilization. On any planet, no matter what its biology or social system, an exponential increase in population will swallow every resource. Conversely, any civilization that engages in serious interstellar exploration and colonization must have exercised zero population growth or something very close to it for many generations.

Because mankind can circumvent evolutionary law, it is incumbent upon him, say evolutionary biologists to develop another law to abide by if he wishes to survive, to not outstrip his food base. He must learn restraint. He must derive some other, wiser way of behaving toward the land. He must be more attentive to the biological imperatives of the system of sun-driven protoplasm upon which he, too, is still dependent. Not because he must, because he lacks inventiveness, but because herein is the accomplishment of the wisdom that for centuries he has aspired to. Having taken on his own destiny, he must now think with critical intelligence about where to defer.

The real potential of Web3 is in allowing businesses and people to collectively function more similarly to biological ecosystems.

our system puts the career clock and the female biological clock in direct conflict.

Resilient strength is the opposite of helplessness. The tree is made strong and resilient by its grounded root system. These roots take nourishment from the ground and grow strong. Grounding also allows the tree to be resilient so that it can yield to the winds of change and not be uprooted. Springiness is the facility to ground and ‘unground’ in a rhythmical way. This buoyancy is a dynamic form of grounding. Aggressiveness is the biological ability to be vigorous and energetic, especially when using instinct and force. In the immobility (traumatized) state, these assertive energies are inaccessible. The restoration of healthy aggression is an essential part in the recovery from trauma. Empowerment is the acceptance of personal authority. It derives from the capacity to choose the direction and execution of one’s own energies. Mastery is the possession of skillful techniques in dealing successfully with threat. Orientation is the process of ascertaining one’s position relative to both circumstance and environment. In these ways the residue of trauma is renegotiated.

It is difficult to overstate the importance of understanding mirror neurons and their function. They may well be central to social learning, imitation, and the cultural transmission of skills and attitudes—perhaps even of the pressed-together sound clusters we call words. By hyperdeveloping the mirror-neuron system, evolution in effect turned culture into the new genome. Armed with culture, humans could adapt to hostile new environments and figure out how to exploit formerly inaccessible or poisonous food sources in just one or two generations—instead of the hundreds or thousands of generations such adaptations would have taken to accomplish through genetic evolution. Thus culture became a significant new source of evolutionary pressure, which helped select brains that had even better mirror-neuron systems and the imitative learning associated with them. The result was one of the many self-amplifying snowball effects that culminated in Homo sapiens, the ape that looked into its own mind and saw the whole cosmos reflected inside.

The administrative and hierarchic aspects seem to be crucial in the evolution of belief systems. The truth is first revealed to all men, but very quickly individuals appear claiming sole authority and a duty to interpret, administer and, if need be, alter this truth in the name of the common good. To this end they establish a powerful and potentially repressive organisation. This phenomenon, which biology shows us is common to any social group, soon transforms the doctrine into a means of achieving control and political power. Divisions, wars and break-ups become inevitable. Sooner or later, the word becomes flesh and the flesh bleeds.

To draw for a moment from an entirely different corner of my life, that part of me still attached to the biological sciences, there is ample evidence that animals — rats and monkeys, for example — that are forced into a subordinate status within their social systems adapt their brain chemistry accordingly, becoming 'depressed' in humanlike ways. Their behavior is anxious and withdrawn; the level of serotonin (the neurotransmitter boosted by some antidepressants) declines in their brains. And — what is especially relevant here — they avoid fighting even in self-defense ... My guess is that the indignities imposed on so many low-wage workers — the drug tests, the constant surveillance, being 'reamed out' by managers — are part of what keeps wages low. If you're made to feel unworthy enough, you may come to think that what you're paid is what you are actually worth.

A happy mood loosens the control of System 2 over performance: when in a good mood, people become more intuitive and more creative but also less vigilant and more prone to logical errors. Here again, as in the mere exposure effect, the connection makes biological sense. A good mood is a signal that things are generally going well, the environment is safe, and it is all right to let one’s guard down. A bad mood indicates that things are not going very well, there may be a threat, and vigilance is required.

Look at any randomly selected piece of your world. Encoded deep in the biology of every cell in every blade of grass, in every insect’s wing, in every bacterium cell, is the history of the third planet from the Sun in a Solar System making its way lethargically around a galaxy called the Milky Way. Its shape, form, function, colour, smell, taste, molecular structure, arrangement of atoms, sequence of bases, and possibilities for the future are all absolutely unique. There is nowhere else in the observable Universe where you will see precisely that little clump of emergent, living complexity. It is wonderful.

We still don’t have a clue about what’s going on in the human brain. We have theories; we just don’t know for sure. We can’t build an electrical circuit, digital or analogue or other, that mimics the biological system. We can’t emulate the behavior. One day in the future, we think we can.

Janx Spirit : Janx Spirit is a rather potent alcoholic beverage, and is used heavily in drinking games that are played in the hyperspace ports that serve the madranite mining belts in the star system of Orion Beta. The game is not unlike the Earth game called Indian Wrestling, and is played like this: Two contestants sit at either side of a table, with a glass in front of each of them. Between them would be placed a bottle of Janx Spirit — as immortalized in that ancient Orion mining song : “Oh don’t give me no more of that Old Janx Spirit No, don’t you give me no more of that Old Janx Spirit For my head will fly, my tongue will lie, my eyes will fry and I may die Won’t you pour me one more of that sinful Old Janx Spirit” Each of the two contestants would then concentrate their will on the bottle and attempt to tip it and pour spirit into the glass of his opponent – who would then have to drink it. The bottle would then be refilled. The game would be played again. And again. Once you started to lose you would probably keep losing, because one of the effects of Janx spirit is to depress telepsychic power. As soon as a predetermined quantity had been consumed, the final loser would have to perform a forfeit, which was usually obscenely biological.

Women do not decide at some time in adulthood that they would like other people to understand them to be women, because being a woman is not an ‘identity’. Women’s experience does not resemble that of men who adopt the ‘gender identity’ of being female or being women in any respect. The idea of ‘gender identity’ disappears biology and all the experiences that those with female biology have of being reared in a caste system based on sex.

Individual humans are not super, but the organism of which we are all tiny cellular parts is most certainly that. The life-form that's so big we forget it's there, that turns minerals on its planet into tools to touch the infinite black gap between stars or probe the obliterating pressures at the bottom of the oceans. We are already part of a superbeing, a monster, a god, a living process that is so all encompassing that it is to an individual life what water is to a fish. We are cells in the body of a three-billion-year-old life-form whose roots are in the Precambrian oceans and whose genetic wiring extends through the living structures of everything on the planet, connecting everything that has ever lived in one immense nervous system.

about the biology of stress and recovery, stress seems to have an effect on the brain similar to that of vaccines on the immune system. In limited doses, it causes brain cells to overcompensate and thus gird themselves against future demands. Neuroscientists call this phenomenon stress inoculation.

Finally, our new brain needs a purpose. A purpose is expressed as a series of goals. In the case of our biological brains, our goals are established by the pleasure and fear centers that we have inherited from the old brain. These primitive drives were initially set by biological evolution to foster the survival of species, but the neocortex has enabled us to sublimate them. Watson’s goal was to respond to Jeopardy! queries. Another simply stated goal could be to pass the Turing test. To do so, a digital brain would need a human narrative of its own fictional story so that it can pretend to be a biological human. It would also have to dumb itself down considerably, for any system that displayed the knowledge of, say, Watson would be quickly unmasked as nonbiological.

Armed with all the powers, enjoying all the wealth they owe to science, our societies are still trying to practice and to teach systems of values already destroyed at the roots by that very science. Man knows at last that he is alone in the indifferent immensity of the universe, whence which he has emerged by chance. His duty, like his fate, is written nowhere.

Many people believe that gender identity...is rooted in biology...Many other people understand that gender is more like language than like biology; that is, while they understand us humans to have a biological capacity to use language, they point out we are not born with a hard-wired language "preinstalled" in our brains. Likewise, while we have a biological capacity to identify with and learn to "speak" from a particular location in a cultural gender system, we don't come into the world with a predetermined gender identity.

I explained my opinion of the ship’s logic. “That is a strange designation,” said the ship. “While I have certain organic elements incorporated into my substructure and decentralized DNA computing components, I am not—in the strictest sense of the term—a biological organism. I have no digestive system. No need for elimination, other than the occasional waste gas and passenger effluvium. Therefore, I have no anus in either real or figurative terms. Therefore, I hardly believe I could qualify to be called an …” “Shut up,” I said.

How Smart Is a Rock? To appreciate the feasibility of computing with no energy and no heat, consider the computation that takes place in an ordinary rock. Although it may appear that nothing much is going on inside a rock, the approximately 1025 (ten trillion trillion) atoms in a kilogram of matter are actually extremely active. Despite the apparent solidity of the object, the atoms are all in motion, sharing electrons back and forth, changing particle spins, and generating rapidly moving electromagnetic fields. All of this activity represents computation, even if not very meaningfully organized. We’ve already shown that atoms can store information at a density of greater than one bit per atom, such as in computing systems built from nuclear magnetic-resonance devices. University of Oklahoma researchers stored 1,024 bits in the magnetic interactions of the protons of a single molecule containing nineteen hydrogen atoms.51 Thus, the state of the rock at any one moment represents at least 1027 bits of memory.

Eyes often have an implicit censorious power.22 Post a large picture of a pair of eyes at a bus stop (versus a picture of flowers), and people become more likely to clean up litter. Post a picture of eyes in a workplace coffee room, and the money paid on the honor system triples. Show a pair of eyes on a computer screen and people become more generous in online economic games.

There are no inherent barriers to our being able to reverse engineer the operating principles of human intelligence and replicate these capabilities in the more powerful computational substrates that will become available in the decades ahead. The human brain is a complex hierarchy of complex systems, but it does not represent a level of complexity beyond what we are already capable of handling.

In terms of biological systems, efficiency is a matter of life or death. And the same is true in terms of business systems.

My mitochondria comprise a very large proportion of me. I cannot do the calculation, but I suppose there is almost as much of them in sheer dry bulk as there is the rest of me. Looked at in this way, I could be taken for a very large, motile colony of respiring bacteria, operating a complex system of nuclei, microtubules, and neurons for the pleasure and sustenance of their families, and running, at the moment, a typewriter.

The woman who later became his wife was sleeping in his bed, her face buried in the pillows and her feet crossed on top of each other like a child's. He watched her sleep and struggled to see her as she was, but what he saw instead were her muscles and bones. He saw right through the skin to where her femur connected to her tibia by way of the ligaments, to the hair web of nerves and the delicate forest of her lungs, to the abstract heart pumping blood through her arteries. It terrified him how easily these systems could fail her.

The offspring cannot rely on its parents for disinterested guidance. One expects the offspring to be preprogrammed to resist some parental manipulation while being open to other forms. When the parent imposes an arbitrary system of reinforcement (punishment and reward) in order to manipulate the offspring to act against its own best interests, selection will favor offspring that resist such schedules of reinforcement.

A lot of business opportunities exist at the intersection of synthetic biology and material ecology. And when that's applied at global systems level scale, it has multiplicative value effect for humanity as a whole.

The systems we will be exploring in order are: ● Breeding Targets: Arousal patterns tied to systems meant to get our ancestors to have sex with things that might bear offspring (e.g., arousal from things like penises, the female form, etc.). ● Inverse Systems: Arousal patterns that arise from a neural mix-up, causing something that disgusts the majority of the population to arouse a small portion of it (e.g., arousal from things like being farted on, dead bodies, having insects poured on one’s face, etc.). ● Emotional States and Concepts / Dominance and Submission: Arousal patterns that stem from either emotional concepts (such as betrayal, transformation, being eaten, etc.) or dominance and submission pathways. ● Emotional Connections to People: While emotional connections do not cause arousal in and of themselves, they do lower the threshold for arousal (i.e., you may become more aroused by a moderately attractive person you love than a very attractive stranger). ● Trope Attraction: Arousal patterns that are enhanced through a target’s adherence to a specific trope (a nurse, a goth person, a cheerleader, etc.). ● Novelty: Arousal patterns tied to the novelty of a particular stimulus. ● Pain and Asphyxiation: Arousal patterns associated with or enhanced by pain and oxygen deprivation. ● Basic Instincts: Remnants of our pre-cognitive mating instincts running off of a “deeper” autopilot-like neurological system (dry humping, etc.) that compel mating behavior without necessarily generating a traditional feeling of arousal. ● Physical Stimuli: Arousal patterns derived from physical interaction (kissing, touching an erogenous zone, etc.). ● Conditioned Responses: Arousal patterns resulting from conditioning (arousal from shoes, doorknobs, etc.).

At its heart, Codependency is a set of behaviors developed to manage the anxiety that comes when our primary attachments are formed with people who are inconsistent or unavailable in their response to us. Our anxiety-based responses to life can include over-reactivity, image management, unrealistic beliefs about our limits, and attempts to control the reality of others to the point where we lose our boundaries, self-esteem, and even our own reality. Ultimately, Codependency is a chronic stress disease, which can devastate our immune system and lead to systemic and even life-threatening illness.

People carry around with them internalization's fixed-feature space learned early in life. Man is like other members of the animal kingdom , first, last and always a prisoner of his biological organism. No matter how hard he tries, it is impossible for him to the best himself of his own culture, where it has penetrated to the roots of his nervous system and determines how he perceives the world.

An organization, a social artifact, is very different from a biological organism. Yet it stands under the law that governs the structure and size of animals and plants: The surface goes up with the square of the radius, but the mass grows with the cube. The larger the animal becomes, the more resources have to be devoted to the mass and to the internal tasks, to circulation and information, to the nervous system, and so on.

The chief causes of the environmental destruction that faces us today are not biological, or the product of individual human choice. They are social and historical, rooted in the productive relations, technological imperatives, and historically conditioned demographic trends that characterize the dominant social system. Hence, what is ignored or downplayed in most proposals to remedy the environmental crisis is the most critical challenge of all: the need to transform the major social bases of environmental degradation, and not simply to tinker with its minor technical bases. As long as prevailing social relations remain unquestioned, those who are concerned about what is happening are left with few visible avenues for environmental action other than purely personal commitments to recycling and green shopping, socially untenable choices between jobs and the environment, or broad appeals to corporations, political policy-makers, and the scientific establishment--the very interests most responsible for the current ecological mess.

For those scientists who take it seriously, Darwinian evolution has functioned more as a philosophical belief system than as a testable scientific hypothesis. This quasi-religious function of the theory is, I think, what lies behind many of the extreme statements that you have doubtless encountered from some scientists opposing any critical analysis of neo-Darwinism in the classroom. It is also why many scientists make public statements about the theory that they would not defend privately to other scientists like me.

... Because the staging of human embryos is complex, owing to the continuous process of change during development, it is proposed that a new system of classification could be developed using the terms mentioned in the Qur'an and Sunnah. The proposed system is simple, comprehensive, and conforms with present embryological knowledge.287 (Dr. Keith L. Moore, Professor Emeritus, Department of Anatomy and Cell Biology, University of Toronto)

If you will not reveal yourself to others, you cannot reveal yourself to yourself. That does not only mean that you suppress who you are, although it also means that. It means that so much of what you could be will never be forced by necessity to come forward. This is a biological truth, as well as a conceptual truth. When you explore boldly, when you voluntarily confront the unknown, you gather information and build your renewed self out of that information. That is the conceptual element. However, researchers have recently discovered that new genes in the central nervous system turn themselves on when an organism is placed (or places itself) in a new situation. These genes code for new proteins. These proteins are the building blocks for new structures in the brain. This means that a lot of you is still nascent, in the most physical of senses, and will not be called forth by stasis. You have to say something, go somewhere and do things to get turned on.

The lessons of relationship that our primordial ancestors learned are deeply encoded in the genetics of our neurobiological circuits of love. They are present from the moment we are born and activated at puberty by the cocktail of neurochemicals. It’s an elegant synchronized system. At first our brain weighs a potential partner, and if the person fits our ancestral wish list, we get a spike in the release of sex chemicals that makes us dizzy with a rush of unavoidable infatuation. It’s the first step down the primeval path of pair-bonding.

The anthropologist Ashley Montagu was among the first to argue that race is a human invention, a social construct, not a biological one, and that in seeking to understand the divisions and disparities in the United States, we have typically fallen into the quicksand and mythology of race. “When we speak of the race problem in America,” he wrote in 1942, “what we really mean is the caste system and the problems which that caste system creates in America.

The anxiety of anger and other “negative” emotions like sadness and rejection may become deeply bound in the body. Eventually it is transmuted into biological changes through the multiple and infinitely subtle cross-connections of the PNI apparatus, the unifying nexus of body/mind. This is the route that leads to organic disease. When anger is disarmed, so is the immune system. Or when the aggressive energy of anger is diverted inward, the immune system becomes confused. Our physiological defences no longer protect us or may even turn mutinous, attacking the body.

Obviously, oxytocin and vasopressin are the grooviest hormones in the universe. Pour them into the water supply, and people will be more charitable, trusting, and empathic. We'd be better parents and would make love, not war (mostly platonic love, though, since people in relationships would give wide berths to everyone else). Best of all, we'd buy all sorts of useless crap, trusting the promotional banners in stores once oxytocin starts spraying out of the ventilation system.

The living cell is the most complex system of its size known to mankind. Its host of specialized molecules, many found nowhere else but within living material, are themselves already enormously complex. They execute a dance of exquisite fidelity, orchestrated with breathtaking precision. Vastly more elaborate than the most complicated ballet, the dance of life encompasses countless molecular performers in synergetic coordination. Yet this is a dance with no sign of a choreographer. No intelligent supervisor, no mystic force, no conscious controlling agency swings the molecules into place at the right time, chooses the appropriate players, closes the links, uncouples the partners, moves them on. The dance of life is spontaneous, self-sustaining, and self-creating.

On the other hand it is possible that human control over the machines may be retained. In that case the average man may have control over certain private machines of his own, such as his car of his personal computer, but control over large systems of machines will be in the hands of a tiny elite -- just as it is today, but with two difference. Due to improved techniques the elite will have greater control over the masses; and because human work will no longer be necessary the masses will be superfluous, a useless burden on the system. If the elite is ruthless the may simply decide to exterminate the mass of humanity. If they are humane they may use propaganda or other psychological or biological techniques to reduce the birth rate until the mass of humanity becomes extinct, leaving the world to the elite. Or, if the elite consist of soft-hearted liberals, they may decide to play the role of good shepherds to the rest of the human race. They will see to it that everyone's physical needs are satisfied, that all children are raised under psychologically hygienic conditions, that everyone has a wholesome hobby to keep him busy, and that anyone who may become dissatisfied undergoes "treatment" to cure his "problem." Of course, life will be so purposeless that people will have to be biologically or psychologically engineered either to remove their need for the power process or to make them "sublimate" their drive for power into some harmless hobby. These engineered human beings may be happy in such a society, but they most certainly will not be free. They will have been reduced to the status of domestic animals.

Well, I do feel like I should mention that I think virginity in general is an arbitrary construct designed by men as a system of control and fear. And it’s heteronormative. And limiting, because why do certain sexual acts preserve virginity and some destroy it? What if I fucked a dildo every night, but I hadn’t fucked a man? Why doesn’t anal sex count? And what if I was with someone and penetration wasn’t an option, for any number of biological or emotional or identity reasons—would that make our sex less somehow? I’d be a virgin forever?

In order to survive, all systems must evolve by providing greater and greater access to the currents that flow through them. This applies to all physical, biological and social systems that survive and thrive.... But let’s take that one step forward... the systems just described are ... constantly evolving. This suggests another design principle: ... design for evolution rather than creating a static design optimizing for the present.

Molecular machines display a key signature or hallmark of design, namely, irreducible complexity. In all irreducibly complex systems in which the cause of the system is known by experience or observation, intelligent design or engineering played a role in the origin of the system... We find such systems within living organisms.

Stress can be bad for you. We no longer die of smallpox or the plague and instead die of stress-related diseases of lifestyle, like heart disease or diabetes, where damage slowly accumulates over time. It is understood how stress can cause or worsen disease or make you more vulnerable to other risk factors. Much of this is even understood on the molecular level. Stress can even cause your immune system to abnormally target hair follicles, causing your hair to turn gray.

The intensive studies of the Qur'an and Hadith in the last four years have revealed a system of classifying human embryos that is amazing since it was recorded in the seventh century A.D... the descriptions in the Qur'an cannot be based on scientific knowledge in the seventh century...288 (Dr. Keith L. Moore, Professor Emeritus, Department of Anatomy and Cell Biology, University of Toronto)

Another flaw of the system is the fact that various danger fronts often require very different firmaments. As a logical superstructure is built upon each, there follow clashes of incommensurable modes of feeling and thought. Then despair can enter through the rifts. In such cases, a person may be obsessed with destructive joy, dislodging the whole artificial apparatus of his life and starting with rapturous horror to make a clean sweep of it. The horror stems from the loss of all sheltering values, the rapture from his by now ruthless identification and harmony with our nature’s deepest secret, the biological unsoundness, the enduring disposition for doom.

In the discoveries of science the harmony of the spheres is also now the harmony of life. And as the eerie illumination of science penetrates evermore deeply into the order of nature, the cosmos appears increasingly to be a vast system finely tuned to generate life and organisms of biology very similar, perhaps identical, to ourselves. All the evidence available in the biological sciences supports the core proposition of traditional natural theology - that the cosmos is a specially designed whole with life and mankind as a fundamental goal and purpose, a whole in which all facets of reality, from the size of galaxies to the thermal capacity of water, have their meaning and explanation in this central fact. Four centuries after the scientific revolution apparently destroyed irretrievably man's special place in the universe, banished Aristotle, and rendered teleological speculation obsolete, the relentless stream of discovery has turned dramatically in favor of teleology and design, and the doctrine of the microcosm is reborn. As I hope the evidence presented in this book has shown, science, which has been for centuries the great ally of atheism and skepticism, has become at last, in the final days of the second millennium, what Newton and many of its early advocates had so fervently wished - the "defender of the anthropocentric faith.

Quantum physicists discovered that physical atoms are made up of vortices of energy that are constantly spinning and vibrating; each atom is like a wobbly spinning top that radiates energy. Because each atom has its own specific energy signature (wobble), assemblies of atoms (molecules) collectively radiate their own identifying energy patterns. So every material structure in the universe, including you and me, radiates a unique energy signature. If it were theoretically possible to observe the composition of an actual atom with a microscope, what would we see? Imagine a swirling dust devil cutting across the desert’s floor. Now remove the sand and dirt from the funnel cloud. What you have left is an invisible, tornado-like vortex. A number of infinitesimally small, dust devil–like energy vortices called quarks and photons collectively make up the structure of the atom. From far away, the atom would likely appear as a blurry sphere. As its structure came nearer to focus, the atom would become less clear and less distinct. As the surface of the atom drew near, it would disappear. You would see nothing. In fact, as you focused through the entire structure of the atom, all you would observe is a physical void. The atom has no physical structure—the emperor has no clothes! Remember the atomic models you studied in school, the ones with marbles and ball bearings going around like the solar system? Let’s put that picture beside the “physical” structure of the atom discovered by quantum physicists. No, there has not been a printing mistake; atoms are made out of invisible energy not tangible matter! So in our world, material substance (matter) appears out of thin air. Kind of weird, when you think about it. Here you are holding this physical book in your hands. Yet if you were to focus on the book’s material substance with an atomic microscope, you would see that you are holding nothing. As it turns out, we undergraduate biology majors were right about one thing—the quantum universe is mind-bending. Let’s look more closely at the “now you see it, now you don’t” nature of quantum physics. Matter can simultaneously be defined as a solid (particle) and as an immaterial force field (wave). When scientists study the physical properties of atoms, such as mass and weight, they look and act like physical matter. However, when the same atoms are described in terms of voltage potentials and wavelengths, they exhibit the qualities and properties of energy (waves). (Hackermüller, et al, 2003; Chapman, et al, 1995; Pool 1995) The fact that energy and matter are one and the same is precisely what Einstein recognized when he concluded that E = mc2. Simply stated, this equation reveals that energy (E) = matter (m, mass) multiplied by the speed of light squared (c2). Einstein revealed that we do not live in a universe with discrete, physical objects separated by dead space. The Universe is one indivisible, dynamic whole in which energy and matter are so deeply entangled it is impossible to consider them as independent elements.

Here is the essence of mankind's creative genius: not the edifices of civilization nor the bang-flash weapons which can end it, but the words which fertilize new concepts like spermatoza attacking an ovum. It might be argued that the Siamese-twin infants of word/idea are the only contribution the human species can, will, or should make to the reveling cosmos. (Yes, our DNA is unique, but so is a salamander's. Yes, we construct artifacts, but so have species ranging from beavers to the architecture ants... Yes, we weave real fabric things from the dreamstuff of mathematics, but the universe is hardwired with arithmetic. Scratch a circle and pi peeps out. Enter a new solar system and Tycho Brahe's formulae lie waiting under the black velvet cloak of space/time. But where has the universe hidden a word under its outer layer of biology, geometry, or insensate rock?)

Every day, hundreds of observations and experiments pour into the hopper of the scientific literature. Many of them don't have much to do with evolution - they're observations about the details of physiology, biochemistry, development, and so on - but many of them do. And every fact that has something to do with evolution confirms its truth. Every fossil that we find, every DNA molecule that we sequence, every organ system that we dissect, supports the idea that species evolved from common ancestors. Despite innumerable possible observations that could prove evolution untrue, we don't have a single one. We don't find mammals in Precambrian rocks, humans in the same layers as dinosaurs, or any other fossils out of evolutionary order. DNA sequencing supports the evolutionary relationships of species originally deduced from the fossil record. And, as natural selection predicts, we find no species with adaptations that only benefit a different species. We do find dead genes and vestigial organs, incomprehensible under the idea of special creation. Despite a million chances to be wrong, evolution always comes up right. That is as close as we can get to a scientific truth.

But the end does happen. Unavoidably. All relationships between living beings end somewhere, somehow. That’s just the way it is. One party dies, or is called away by other biological needs. Emotions are transient by nature. They’re temporary states brought on by neurophysiological changes that aren’t meant to be long-lasting. The nervous system must revert back to homeostasis. All relationships associated with affective events are destined to end.

Even if we have a reliable criterion for detecting design, and even if that criterion tells us that biological systems are designed, it seems that determining a biological system to be designed is akin to shrugging our shoulders and saying God did it. The fear is that admitting design as an explanation will stifle scientific inquiry, that scientists will stop investigating difficult problems because they have a sufficient explanation already. But design is not a science stopper. Indeed, design can foster inquiry where traditional evolutionary approaches obstruct it. Consider the term "junk DNA." Implicit in this term is the view that because the genome of an organism has been cobbled together through a long, undirected evolutionary process, the genome is a patchwork of which only limited portions are essential to the organism. Thus on an evolutionary view we expect a lot of useless DNA. If, on the other hand, organisms are designed, we expect DNA, as much as possible, to exhibit function. And indeed, the most recent findings suggest that designating DNA as "junk" merely cloaks our current lack of knowledge about function. For instance, in a recent issue of the Journal of Theoretical Biology, John Bodnar describes how "non-coding DNA in eukaryotic genomes encodes a language which programs organismal growth and development." Design encourages scientists to look for function where evolution discourages it. Or consider vestigial organs that later are found to have a function after all. Evolutionary biology texts often cite the human coccyx as a "vestigial structure" that hearkens back to vertebrate ancestors with tails. Yet if one looks at a recent edition of Gray’s Anatomy, one finds that the coccyx is a crucial point of contact with muscles that attach to the pelvic floor. The phrase "vestigial structure" often merely cloaks our current lack of knowledge about function. The human appendix, formerly thought to be vestigial, is now known to be a functioning component of the immune system.

Owing to the shape of a bell curve, the education system is geared to the mean. Unfortunately, that kind of education is virtually calculated to bore and alienate gifted minds. But instead of making exceptions where it would do the most good, the educational bureaucracy often prefers not to be bothered. In my case, for example, much of the schooling to which I was subjected was probably worse than nothing. It consisted not of real education, but of repetition and oppressive socialization (entirely superfluous given the dose of oppression I was getting away from school). Had I been left alone, preferably with access to a good library and a minimal amount of high-quality instruction, I would at least have been free to learn without useless distractions and gratuitous indoctrination. But alas, no such luck. Let’s try to break the problem down a bit. The education system […] is committed to a warm and fuzzy but scientifically counterfactual form of egalitarianism which attributes all intellectual differences to environmental factors rather than biology, implying that the so-called 'gifted' are just pampered brats who, unless their parents can afford private schooling, should atone for their undeserved good fortune by staying behind and enriching the classroom environments of less privileged students. This approach may appear admirable, but its effects on our educational and intellectual standards, and all that depends on them, have already proven to be overwhelmingly negative. This clearly betrays an ulterior motive, suggesting that it has more to do with social engineering than education. There is an obvious difference between saying that poor students have all of the human dignity and basic rights of better students, and saying that there are no inherent educationally and socially relevant differences among students. The first statement makes sense, while the second does not. The gifted population accounts for a very large part of the world’s intellectual resources. As such, they can obviously be put to better use than smoothing the ruffled feathers of average or below-average students and their parents by decorating classroom environments which prevent the gifted from learning at their natural pace. The higher we go on the scale of intellectual brilliance – and we’re not necessarily talking just about IQ – the less support is offered by the education system, yet the more likely are conceptual syntheses and grand intellectual achievements of the kind seldom produced by any group of markedly less intelligent people. In some cases, the education system is discouraging or blocking such achievements, and thus cheating humanity of their benefits.

Anti-feminism is not sexism. It does not defend the various types of physical, sexual and moral violence against women in the family and society. It does not claim to violate the natural rights of women, which is expressed in the constitution and the legal system as a whole. Instead, anti-feminism supports the innate biological differences among men and women, and as a final result it is directed against gender-blindness -- a unisex trend that artificially increases due to feminism in modern global civilization. To protect the natural rights of women, you don't need to be a feminist, you have to be a humanist who has devoted himself or herself to protecting all humans.

The fact is that hundreds of trillions of microbial “invaders,” mostly in our gut, are absolutely necessary for our survival, and there are ten times more of them than cells in the human body. Because the body cannot survive without its microbes (collectively called the “microbiome”), they are the functional equivalent of any of our other vital organ systems. In (belated) recognition of the importance of the microbiome, humans and most other organisms are now properly defined as superorganisms (complex organisms composed of many smaller organisms). (Saey

Were we dealing with a spectrum-based system that described male and female sexuality with equal accuracy, data taken from gay males would look similar to data taken from straight females—and yet this is not what we see in practice. Instead, the data associated with gay male sexuality presents a mirror image of data associated with straight males: Most gay men are as likely to find the female form aversive as straight men are likely to find the male form aversive. In gay females we observe a similar phenomenon, in which they mirror straight females instead of appearing in the same position on the spectrum as straight men—in other words, gay women are just as unlikely to find the male form aversive as straight females are to find the female form aversive. Some of the research highlighting these trends has been conducted with technology like laser doppler imaging (LDI), which measures genital blood flow when individuals are presented with pornographic images. The findings can, therefore, not be written off as a product of men lying to hide middling positions on the Kinsey scale due to a higher social stigma against what is thought of in the vernacular as male bisexuality/pansexuality. We should, however, note that laser Doppler imaging systems are hardly perfect, especially when measuring arousal in females. It is difficult to attribute these patterns to socialization, as they are observed across cultures and even within the earliest of gay communities that emerged in America, which had to overcome a huge amount of systemic oppression to exist. It’s a little crazy to argue that the socially oppressed sexuality of the early American gay community was largely a product of socialization given how much they had overcome just to come out. If, however, one works off the assumptions of our model, this pattern makes perfect sense. There must be a stage in male brain development that determines which set of gendered stimuli is dominant, then applies a negative modifier to stimuli associated with other genders. This stage does not apparently take place during female sexual development. 

In America, Rousseauism has turned Freud’s conflict-based psychoanalysis into weepy hand-holding. Contemporary liberalism is untruthful about cosmic realities. Therapy, defining anger and hostility in merely personal terms, seeks to cure what was never a problem before Rousseau. Mediterranean, as well as African-American, culture has a lavish system of language and gesture to channel and express negative emotion. Rousseauists who take the Utopian view of personality are always distressed or depressed over world outbreaks of violence and anarchy. But because, as a Sadean, I believe history is in nature and of it, I tend to be far more cheerful and optimistic than my liberal friends. Despite crime’s omnipresence, things work in society, because biology compels it. Order eventually restores itself, by psychic equilibrium. Films like Seven Samurai (1954) and Two Women (1961) accurately show the breakdown of social controls as a regression to animal-like squalor.

Cambridge philosopher, Dr. C. D. Broad, “that we should do well to consider much more seriously than we have hitherto been inclined to do the type of theory which Bergson put forward in connection with memory and sense perception. The suggestion is that the function of the brain and nervous system and sense organs is in the main eliminative and not productive. Each person is at each moment capable of remembering all that has ever happened to him and of perceiving everything that is happening everywhere in the universe. The function of the brain and nervous system is to protect us from being overwhelmed and confused by this mass of largely useless and irrelevant knowledge, by shutting out most of what we should otherwise perceive or remember at any moment, and leaving only that very small and special selection which is likely to be practically useful.” According to such a theory, each one of us is potentially Mind at Large. But in so far as we are animals, our business is at all costs to survive. To make biological survival possible, Mind at Large has to be funneled through the reducing valve of the brain and nervous system. What comes out at the other end is a measly trickle of the kind of consciousness which will help us to stay alive on the surface of this particular planet. To formulate and express the contents of this reduced awareness, man has invented and endlessly elaborated those symbol-systems and implicit philosophies which we call languages.

For Dawkins, atheism is a necessary consequence of evolution. He has argued that the religious impulse is simply an evolutionary mistake, a ‘misfiring of something useful’, it is a kind if virus, parasitic on cognitive systems naturally selected because they had enabled a species to survive. Dawkins is an extreme exponent of the scientific naturalism, originally formulated by d’Holbach, that has now become a major worldview among intellectuals. More moderate versions of this “scientism” have been articulated by Carl Sagan, Steven Weinberg, and Daniel Dennett, who have all claimed that one has to choose between science and faith. For Dennett, theology has been rendered superfluous, because biology can provide a better explanation of why people are religious. But for Dawkins, like the other “new atheists” – Sam Harris, the young American philosopher and student of neuroscience, and Christopher Hitchens, critic and journalist – religion is the cause of the problems of our world; it is the source of absolute evil and “poisons everything.” They see themselves in the vanguard of a scientific/rational movement that will eventually expunge the idea of God from human consciousness. But other atheists and scientists are wary of this approach. The American zoologist Stephen Jay Gould (1941-2002) followed Monod in his discussion of the implications of evolution. Everything in the natural world could indeed be explained by natural selection, but Gould insisted that science was not competent to decide whether God did or did not exist, because it could only work with natural explanations. Gould had no religious axe to grind; he described himself as an atheistically inclined agnostic, but pointed out that Darwin himself had denied he was an atheist and that other eminent Darwinians - Asa Gray, Charles D. Walcott, G. G. Simpson, and Theodosius Dobzhansky - had been either practicing Christians or agnostics. Atheism did not, therefore, seem to be a necessary consequence of accepting evolutionary theory, and Darwinians who held forth dogmatically on the subject were stepping beyond the limitations that were proper to science.

Throughout the human life span there remains a constant two-way interaction between psychological states and the neurochemistry of the frontal lobes, a fact that many doctors do not pay enough attention to. One result is the overreliance on medications in the treatment of mental disorders. Modern psychiatry is doing too much listening to Prozac and not enough listening to human beings; people’s life histories should be given at least as much importance as the chemistry of their brains. The dominant tendency is to explain mental conditions by deficiencies of the brain’s chemical messengers, the neurotransmitters. As Daniel J. Siegel has sharply remarked, “We hear it said everywhere these days that the experience of human beings comes from their chemicals.” Depression, according to the simple biochemical model, is due to a lack of serotonin — and, it is said, so is excessive aggression. The answer is Prozac, which increases serotonin levels in the brain. Attention deficit is thought to be due in part to an undersupply of dopamine, one of the brain’s most important neurotransmitters, crucial to attention and to experiencing reward states. The answer is Ritalin. Just as Prozac elevates serotonin levels, Ritalin or other psychostimulants are thought to increase the availability of dopamine in the brain’s prefrontal areas. This is believed to increase motivation and attention by improving the functioning of areas in the prefrontal cortex. Although they carry some truth, such biochemical explanations of complex mental states are dangerous oversimplifications — as the neurologist Antonio Damasio cautions: "When it comes to explaining behavior and mind, it is not enough to mention neurochemistry... The problem is that it is not the absence or low amount of serotonin per se that “causes” certain manifestations. Serotonin is part of an exceedingly complicated mechanism which operates at the level of molecules, synapses, local circuits, and systems, and in which sociocultural factors, past and present, also intervene powerfully. The deficiencies and imbalances of brain chemicals are as much effect as cause. They are greatly influenced by emotional experiences. Some experiences deplete the supply of neurotransmitters; other experiences enhance them. In turn, the availability — or lack of availability — of brain chemicals can promote certain behaviors and emotional responses and inhibit others. Once more we see that the relationship between behavior and biology is not a one-way street.

To be human is the only way out of being human. An alternative exit— either by unbinding sentience from sapience or by circumventing sapience in favour of a direct engagement with the technological artefact—cannot go beyond the human. Rather it leads to a culture of cognitive pettiness and self-deception that is daily fodder for the most parochial and utilitarian political systems that exist on the planet. In delivering sentience from its so-called sapient yoke, one does not become posthuman, or even animal, but falls back on an ideologically charged ‘biological chauvinism’ that sapience ought to overcome, for it is the very idea of humanist conservatism that misrepresents what is accidental and locally contingent as what is necessary and universal. In discarding the human in the hope of an immediate contact with superintelligence or a self-realization of the technological artefact, one either surreptitiously subjects the future to the predetermined goals of conservative humanism, or subscribes to a future that is simply the teleological actualization of final causes and thus a resurrection of the well-worn Aristotelian fusion of reasons and causes. Human sapience is the only project of exit.

More daunting for those who hope for scientific and social progress, the genetic argument is easily used to justify all kinds of inequalities and injustices that are otherwise hard to defend. It serves a deeply conservative function: if a phenomenon like addiction is determined mostly by biological heredity, we are spared from having to look at how our social environment supports, or does not support, the parents of young children and at how social attitudes, prejudices, and policies burden, stress, and exclude certain segments of the population and thereby increase their propensity for addiction. The writer Louis Menand said it well in a New Yorker article: “It’s all in the genes”: an explanation for the way things are that does not threaten the way things are. Why should someone feel unhappy or engage in antisocial behavior when that person is living in the freest and most prosperous nation on earth? It can’t be the system! There must be a flaw in the wiring somewhere.

The pineal gland is activated by light and controls the body's bio- rhythms in concert with the hypothalamus gland which regulates hunger, thirst, sexual desire and the biological clock that dictates how fast we age. Look at the potential for mass control if you can externally suppress and manipulate the pineal and hypothalamus glands alone. You can make it much harder to perceive beyond the five senses, decide how quickly people age, how much they want sex, when they are hungry and thirsty and for how long. This is the key reason for putting sodium fluoride into water supplies and toothpaste. The pineal gland absorbs more fluoride than any other part of the body and becomes calcified by this highly-damaging toxin. Sodium fluoride is an appalling waste product of the aluminum industry and has been used in rat poison. It causes cancer, genetic damage, Alzheimer's disease, disrupts the endocrine system and dumbs down the brain. It was added to drinking water in the Nazi concentration camps to make the inmates more acquiescent and docile.

Whey protein Whey protein has got more bad press than whisky, gin, rum, wine, beer, and even grass. Whey protein is a powder made from milk which you mix with water to turn into a drink. It has the best biological value of protein; which means that almost every gram of whey you consume gets used for its intended purpose and is absorbed by the body. Whey isolate, made from whey protein is a boon for lactose intolerant vegetarians like me as it doesn’t irritate the stomach or the intestines. Whey protein has been accused of affecting the kidney, liver and heart but this isn’t true. Although superstars, cricketers and doctors advertise for the so called ‘Protein drinks’, (especially for children, easy targets perhaps, not to mention their parents’ obsession with their height), the reality is that these drinks are so loaded in sugar and have such miniscule amounts of protein (not to mention poor biological value too) that they really do much more harm than any good. And a nutrient is never specifically beneficial for a particular age group. Whey protein on the other hand is easy on the system, has zero sugar, and is easy to digest. If you weight train regularly or run long distances, whey protein will become a necessity. (It also comes in all flavours: chocolate, vanilla, strawberry and many more.) Word of caution: whey protein is a supplement. It is not supposed to be used as an alternative to eating correctly. Consuming adequate protein, carbs and fat by means of a well-balanced diet is a must. Only then can whey protein be of any help. Like with everything else, if you overdo it or depend on it alone to provide you with protein, you stand to lose out on its considerable benefits.

There is a significant hereditary contribution to ADD but I do not believe any genetic factor is decisive in the emergence of ADD traits in any child. Genes are codes for the synthesis of the proteins that give a particular cell its characteristic structure and function. They are, as it were, alive and dynamic architectural and mechanical plans. Whether the plan becomes realized depends on far more than the gene itself. It is determined, for the most part, by the environment. To put it differently, genes carry potentials inherent in the cells of a given organism. Which of multiple potentials become expressed biologically is a question of life circumstances. Were we to adopt the medical model — only temporarily, for the sake of argument — a genetic explanation by itself would still be unsuitable. Medical conditions for which genetic inheritance are fully or even mostly responsible, such as muscular dystrophy, are rare. “Few diseases are purely genetic,” says Michael Hayden, a geneticist at the University of British Columbia and a world-renowned researcher into Huntington’s disease. “The most we can say is that some diseases are strongly genetic.” Huntington’s is a fatal degeneration of the nervous system based on a single gene that, if inherited, will almost invariably cause the disease. But not always. Dr. Hayden mentions cases of persons with the gene who live into ripe old age without any signs of the disease itself. “Even in Huntington’s, there must be some protective factor in the environment,” Dr. Hayden says.

Despite the intervening six decades of scientific inquiry since Selye’s groundbreaking work, the physiological impact of the emotions is still far from fully appreciated. The medical approach to health and illness continues to suppose that body and mind are separable from each other and from the milieu in which they exist. Compounding that mistake is a definition of stress that is narrow and simplistic. Medical thinking usually sees stress as highly disturbing but isolated events such as, for example, sudden unemployment, a marriage breakup or the death of a loved one. These major events are potent sources of stress for many, but there are chronic daily stresses in people’s lives that are more insidious and more harmful in their long-term biological consequences. Internally generated stresses take their toll without in any way seeming out of the ordinary. For those habituated to high levels of internal stress since early childhood, it is the absence of stress that creates unease, evoking boredom and a sense of meaninglessness. People may become addicted to their own stress hormones, adrenaline and cortisol, Hans Selye observed. To such persons stress feels desirable, while the absence of it feels like something to be avoided. When people describe themselves as being stressed, they usually mean the nervous agitation they experience under excessive demands — most commonly in the areas of work, family, relationships, finances or health. But sensations of nervous tension do not define stress — nor, strictly speaking, are they always perceived when people are stressed. Stress, as we will define it, is not a matter of subjective feeling. It is a measurable set of objective physiological events in the body, involving the brain, the hormonal apparatus, the immune system and many other organs. Both animals and people can experience stress with no awareness of its presence. “Stress is not simply nervous tension,” Selye pointed out. “Stress reactions do occur in lower animals, and even in plants, that have no nervous systems…. Indeed, stress can be produced under deep anaesthesia in patients who are unconscious, and even in cell cultures grown outside the body.” Similarly, stress effects can be highly active in persons who are fully awake, but who are in the grip of unconscious emotions or cut off from their body responses. The physiology of stress may be triggered without observable effects on behaviour and without subjective awareness, as has been shown in animal experiments and in human studies.

We have good news and bad news. The good news is that the dismal vision of human sexuality reflected in the standard narrative is mistaken. Men have not evolved to be deceitful cads, nor have millions of years shaped women into lying, two-timing gold-diggers. But the bad news is that the amoral agencies of evolution have created in us a species with a secret it just can’t keep. Homo sapiens evolved to be shamelessly, undeniably, inescapably sexual. Lusty libertines. Rakes, rogues, and roués. Tomcats and sex kittens. Horndogs. Bitches in heat.1 True, some of us manage to rise above this aspect of our nature (or to sink below it). But these preconscious impulses remain our biological baseline, our reference point, the zero in our own personal number system. Our evolved tendencies are considered “normal” by the body each of us occupies. Willpower fortified with plenty of guilt, fear, shame, and mutilation of body and soul may provide some control over these urges and impulses. Sometimes. Occasionally. Once in a blue moon. But even when controlled, they refuse to be ignored. As German philosopher Arthur Schopenhauer pointed out, Mensch kann tun was er will; er kann aber nicht wollen was er will. (One can choose what to do, but not what to want.) Acknowledged or not, these evolved yearnings persist and clamor for our attention. And there are costs involved in denying one’s evolved sexual nature, costs paid by individuals, couples, families, and societies every day and every night. They are paid in what E. O. Wilson called “the less tangible currency of human happiness that must be spent to circumvent our natural predispositions.”2 Whether or not our society’s investment in sexual repression is a net gain or loss is a question for another time. For now, we’ll just suggest that trying to rise above nature is always a risky, exhausting endeavor, often resulting in spectacular collapse. Any attempt to understand who we are, how we got to be this way, and what to do about it must begin by facing up to our evolved human sexual predispositions. Why do so many forces resist our sustained fulfillment? Why is conventional marriage so much damned work? How has the incessant, grinding campaign of socio-scientific insistence upon the naturalness of sexual monogamy combined with a couple thousand years of fire and brimstone failed to rid even the priests, preachers, politicians, and professors of their prohibited desires? To see ourselves as we are, we must begin by acknowledging that of all Earth’s creatures, none is as urgently, creatively, and constantly sexual as Homo sapiens.

The world has been changing even faster as people, devices and information are increasingly connected to each other. Computational power is growing and quantum computing is quickly being realised. This will revolutionise artificial intelligence with exponentially faster speeds. It will advance encryption. Quantum computers will change everything, even human biology. There is already one technique to edit DNA precisely, called CRISPR. The basis of this genome-editing technology is a bacterial defence system. It can accurately target and edit stretches of genetic code. The best intention of genetic manipulation is that modifying genes would allow scientists to treat genetic causes of disease by correcting gene mutations. There are, however, less noble possibilities for manipulating DNA. How far we can go with genetic engineering will become an increasingly urgent question. We can’t see the possibilities of curing motor neurone diseases—like my ALS—without also glimpsing its dangers. Intelligence is characterised as the ability to adapt to change. Human intelligence is the result of generations of natural selection of those with the ability to adapt to changed circumstances. We must not fear change. We need to make it work to our advantage. We all have a role to play in making sure that we, and the next generation, have not just the opportunity but the determination to engage fully with the study of science at an early level, so that we can go on to fulfil our potential and create a better world for the whole human race. We need to take learning beyond a theoretical discussion of how AI should be and to make sure we plan for how it can be. We all have the potential to push the boundaries of what is accepted, or expected, and to think big. We stand on the threshold of a brave new world. It is an exciting, if precarious, place to be, and we are the pioneers. When we invented fire, we messed up repeatedly, then invented the fire extinguisher. With more powerful technologies such as nuclear weapons, synthetic biology and strong artificial intelligence, we should instead plan ahead and aim to get things right the first time, because it may be the only chance we will get. Our future is a race between the growing power of our technology and the wisdom with which we use it. Let’s make sure that wisdom wins.

Order Out of Chaos ... At the right temperature ... two peptide molecules will stay together long enough on average to find a third. Then the little trio finds a fourth peptide to attract into the little huddle, just through the random side-stepping and tumbling induced by all the rolling water molecules. Something extraordinary is happening: a larger structure is emerging from a finer system, not in spite of the chaotic and random motion of that system but because of it. Without the chaotic exploration of possibilities, the rare peptide molecules would never find each other, would never investigate all possible ways of aggregating so that the tape-like polymers emerge as the most likely assemblies. It is because of the random motion of all the fine degrees of freedom that the emergent, larger structures can assume the form they do. Even more is true when the number of molecules present becomes truly enormous, as is automatically the case for any amount of matter big enough to see. Out of the disorder emerges a ... pattern of emergent structure from a substrate of chaos.... The exact pressure of a gas, the emergence of fibrillar structures, the height in the atmosphere at which clouds condense, the temperature at which ice forms, even the formation of the delicate membranes surrounding every living cell in the realm of biology -- all this beauty and order becomes both possible and predictable because of the chaotic world underneath them.... Even the structures and phenomena that we find most beautiful of all, those that make life itself possible, grow up from roots in a chaotic underworld. Were the chaos to cease, they would wither and collapse, frozen rigid and lifeless at the temperatures of intergalactic space. This creative tension between the chaotic and the ordered lies within the foundations of science today, but it is a narrative theme of human culture that is as old as any. We saw it depicted in the ancient biblical creation narratives of the last chapter, building through the wisdom, poetic and prophetic literature. It is now time to return to those foundational narratives as they attain their climax in a text shot through with the storm, the flood and the earthquake, and our terrifying ignorance in the face of a cosmos apparently out of control. It is one of the greatest nature writings of the ancient world: the book of Job.

There are, as you have just seen, two agendas being pursued here tonight," the Countess lectured amiably. "The political one of the old men—an annual renewal of the forms of the Vor—and the genetic agenda of the old women. The men imagine theirs is the only one, but that's just an ego-serving self-delusion. The whole Vor system is founded on the women's game, underneath. The old men in government councils spend their lives arguing against or scheming to fund this or that bit of off-planet military hardware. Meanwhile, the uterine replicator is creeping in past their guard, and they aren't even conscious that the debate that will fundamentally alter Barrayar's future is being carried on right now among their wives and daughters. To use it, or not to use it? Too late to keep it out, it's already here. The middle classes are picking it up in droves. Every mother who loves her daughter is pressing for it, to spare her the physical dangers of biological childbearing. They're fighting not the old men, who haven't got a clue, but an old guard of their sisters who say to their daughters, in effect, We had to suffer, so must you! Look around tonight, Mark. You're witnessing the last generation of men and women on Barrayar who will dance this dance in the old way. The Vor system is about to change on its blindest side, the side that looks to—or fails to look to—its foundation. Another half generation from now, it's not going to know what hit it.