Syndrome Down Quotes

I've been doing this a long time- manipulating people to get my way. That's why you think you love me. Because I've broken you down and built you back up to believe it. It wasn't an accident. Once you leave this behind..... you'll see that. -Caleb

Not one day in anyone’s life is an uneventful day, no day without profound meaning, no matter how dull and boring it might seem, no matter whether you are a seamstress or a queen, a shoeshine boy, or a movie star, a renowned philosopher or a Down’s-syndrome child. Because in every day of your life, there are opportunities to perform little kindnesses for others, both by conscious acts of will and unconscious example. Each smallest act of kindness—even just words of hope when they are needed, the remembrance of a birthday, a compliment that engenders a smile—reverberates across great distances and spans of time, affecting lives unknown to the one whose generous spirit was the source of this good echo, because kindness is passed on and grows each time it’s passed, until a simple courtesy becomes an act of selfless courage years later and far away. Likewise, each small meanness, each thoughtless expression of hatred, each envious and bitter act, regardless of how petty, can inspire others, and is therefore the seed that ultimately produces evil fruit, poisoning people whom you have never met and never will. All human lives are so profoundly and intricately entwined—those dead, those living, those generations yet to come—that the fate of all is the fate of each, and the hope of humanity rests in every heart and in every pair of hands. Therefore, after every failure, we are obliged to strive again for success, and when faced with the end of one thing, we must build something new and better in the ashes, just as from pain and grief, we must weave hope, for each of us is a thread critical to the strength—to the very survival of the human tapestry. Every hour in every life contains such often-unrecognized potential to affect the world that the great days and thrilling possibilities are combined always in this momentous day.

In the 1960s, Valerie (Hobson) Profumo became the first show-business mother to talk publicly about Down’s syndrome. She was instrumental in founding Three Roses, England’s first charity to support families with Down’s children.

When you focus on someone's disability you'll overlook their abilities, beauty and uniqueness. Once you learn to accept and love them for who they are, you subconsciously learn to love yourself unconditionally.

The America I know and love is not one in which my parents or my baby with Down syndrome will have to stand in front of Obama’s ‘death panel’ so his bureaucrats can decide, based on a subjective judgment of their ‘level of productivity in society,’ whether they are worthy of health care. Such a system is downright evil.

Part of the function of memory is to forget; the omni-retentive mind will break down and produce at best an idiot savant who can recite a telephone book, and at worst a person to whom every grudge and slight is as yesterday's.

Turn down the volume of your negative inner voice and create a nurturing inner voice to take it’s place. When you make a mistake, forgive yourself, learn from it, and move on instead of obsessing about it. Equally important, don’t allow anyone else to dwell on your mistakes or shortcomings or to expect perfection from you.

Often people ask, "How can you say you're blessed to have a son with Down syndrome?" My outlook on life has forever changed. I see my own challenges differently. He's always showing me that life is so much bigger than self.

My children taught me the true meaning of unconditional love.

What would happen, they conjectured, if they simply went on assuming their children would do everything. Perhaps not quickly. Perhaps not by the book. But what if they simply erased those growth and development charts, with their precise, constricting points and curves? What if they kept their expectations but erased the time line? What harm could it do? Why not try?

I Have a Dream... someday my son, Zyon and ALL individuals with disabilities will be seen as HUMAN beings. I Have a Dream... someday the human & civil rights of individuals with disabilities are honored and they are treated as equals. I Have a Dream... someday ALL parents who have children with disabilities see their child as a blessing and not a burden. I Have a Dream... someday there will be more jobs and opportunities for individuals with disabilities. I Have a Dream... someday there will be UNITY "within" the disabled community. I HAVE A DREAM!!!

Poor innocent me, just going about my business, then you raped me down the ear with your gun." Lindsay nicks the bottle, smirking just slightly, and say's " You loved it, you tart.

Valentine clears his throat. "So. Why can't you just say it?" "Say what?" "You know what." "It's hardly the time or place." "It is if you're dying." "I can't." "You're a dick. Just fucking say it!" "I can't! I'm... English." "What am I, a Martian? I say it all the time. I know you love me, why can't you say it?" "If you know, then why do I have to?" "You're missing the point a bit." "I took your bullet, you little twat, don't you dare question whether I love you." "Yeah, but you could say it." The throb of the gunshots is pounding all down his arm and body. The pain's so bad he wants to cry, like he's five and he's skinned his knee coming off his bike. "Je t'aime," he says, through gritted teeth, to shut the kid up. "Je ne sais pas pourquoi. Tu es... complètement bête, tu t'habilles comme une pute travestie, je hais ta musique, tu es fou, tu me rends fou, mais je suis fou de toi et je pense à toi tout le temps et je t'aime, oui. Tu comprends? Je t'aime. Seulement... pas en anglais. Je ne peux pas." Valentine's shifting about like he's uncomfortable. "I ain't got no idea what you just said but I think I need to change my pants." "Maintenant, ta gueule.

If there are bullets, I’m between you and them. If you get taken, I’m hunting you down till my last breath. And if you end up in hell, I’ll storm the fucking place until the fires go out.

I've never told another soul about the stories I make up while I'm trying to fall asleep, and I would never even consider writing them down. They're just too personal. Nathan fell silent as well, and I realized that maybe I wasn't the only one who felt that way. I wondered how many people in the world have daydreams spinning around in their heads that they would never put into words. Probably more than you would think.

Like Beauty locked up in the Beast’s castle, I developed my own brand of Stockholm syndrome, identifying with my captor.

Being alone can be a very effective way of calming down and is also enjoyable, especially if engaged in a special interest, one of the greatest pleasures in life for someone with Asperger’s syndrome.

Since when do the media care about the disabled? I don’t remember a lot of gnashing of teeth when Fox’s Family Guy made fun of Sarah Palin’s Down syndrome child, Trig. They

I know of other mothers who have children with disabilities,and right away they loved them and decided to fight for them. That isn’t my story.

My faith has strengthen. God has shown me through my son with Down syndrome to not take anything for granted. I'm more grateful.

Dad they think she has Down Syndrome." He smiled genuinely as his eyes welled up with tears. "That's okay. We love her.

Just as when the caterpillar thought the world was over, it became a butterfly.

Nell's husband has short-man syndrome. Eddie is one of those deadly dull people who is so upbeat that I suspect he would subconsciously like to go through the neighborhood, house by house, with a machine gun. He seems oblivious to the effect that his long, rambling monologues have on people - he doesn't notice the blank faces, the fingers flexing like those of people buried alive, the ocular tics. You could write down his words verbatim, show them to him, and he'd probably say, 'I know someone just like that!' Then he'd tell you about that person until your teeth hurt. His hostage-taking is passive-aggressive.

He tries again, swallowing hard to ease away the painful lump in his throat. "It's just important. I love you. I'm yours. I need people to know." "Alright," Lindsay says suddenly. He leans down to grab at Pip's bag, throwing stuff out onto the carpet, his iPod and phone and wallet and gloves and Attitude magazine until he finds what he's looking for, a green marker pen, and holds it between his teeth while he starts tugging at the hem of Pip's t-shirt. Pip's too surprised to do anything but submit, he lets Lindsay peel off his t-shirt and throw that on top of all the things from his bag then just watches as Lindsay pulls the pen out of the cap in his mouth and signs his name in big green letters on the side of Pip's stomach. He holds his breath, trying not to suck in the belly fat everybody else keeps telling him is imaginary. "There, you're mine, are you fucking happy now?" Lindsay snaps, and throws the recapped pen across the room to get lost in the bookcase somewhere.

These Cro-Magnon people were identical to us: they had the same physique, the same brain, the same looks. And, unlike all previous hominids who roamed the earth, they could choke on food. That may seem a trifling point, but the slight evolutionary change that pushed man's larynx deeper into his throat, and thus made choking a possibility, also brought with it the possibility of sophisticated, well articulated speech. Other mammals have no contact between their air passages and oesophagi. They can breathe and swallow at the same time, and there is no possibility of food going down the wrong way. But with Homo sapiens food and drink must pass over the larynx on the way to the gullet and thus there is a constant risk that some will be inadvertently inhaled. In modern humans, the lowered larynx isn't in position from birth. It descends sometime between the ages of three and five months - curiously, the precise period when babies are likely to suffer from Sudden Infant Death Syndrome. At all events, the descended larynx explains why you can speak and your dog cannot.

I know that when I walk out of the studio someday and there is a child who has Downs Syndrome, for instance, and that child comes up and gives me a hug, I know that that's the field I want to be growing in. Because I see that people who are not the fancy people of this world are the ones who seem to nourish my soul. And I want to learn how to be the best receiver that I can ever be. Because I think graceful receiving is one of the most wonderful gifts we can give anybody.

when describing children with Down's Syndrome, he called a child 'heart spontaneous'.

Some call it Down's Syndrome I call it Up's Syndrome.

Makes sense,” the young woman remarked. “Down here you live life to the fullest, while up there your life is empty, worthless. You need a lot of real time to buy just a minute of dreams.

They’re kind. Content. They don’t judge. They don’t hide their feelings. There’s no hidden agenda. Complete acceptance. If that isn’t grace, I don’t know what is. I’m not saying people with Down syndrome are perfect or always easy. That would be to trivialize them, make them sound like pets. What I am saying is that in my experience they make better humans than most.” He smiled again. “Than me. And I think that’s worth fighting for, don’t you?

For the rest of his life, he realized, he would be torn like this, aware of Phoebe's awkwardness, the difficulties she encountered in the world simply by being different, and ye propelled beyond all this by her direct and guileless love. By her love, yes, and, he realized...by his own new and strangely uncomplicated love for her.

Well, my dear sisters, the gospel is the good news that can free us from guilt. We know that Jesus experienced the totality of mortal existence in Gethsemane. It's our faith that he experienced everything- absolutely everything. Sometimes we don't think through the implications of that belief. We talk in great generalities about the sins of all humankind, about the suffering of the entire human family. But we don't experience pain in generalities. We experience it individually. That means he knows what it felt like when your mother died of cancer- how it was for your mother, how it still is for you. He knows what it felt like to lose the student body election. He knows that moment when the brakes locked and the car started to skid. He experienced the slave ship sailing from Ghana toward Virginia. He experienced the gas chambers at Dachau. He experienced Napalm in Vietnam. He knows about drug addiction and alcoholism. Let me go further. There is nothing you have experienced as a woman that he does not also know and recognize. On a profound level, he understands the hunger to hold your baby that sustains you through pregnancy. He understands both the physical pain of giving birth and the immense joy. He knows about PMS and cramps and menopause. He understands about rape and infertility and abortion. His last recorded words to his disciples were, "And, lo, I am with you always, even unto the end of the world." (Matthew 28:20) He understands your mother-pain when your five-year-old leaves for kindergarten, when a bully picks on your fifth-grader, when your daughter calls to say that the new baby has Down syndrome. He knows your mother-rage when a trusted babysitter sexually abuses your two-year-old, when someone gives your thirteen-year-old drugs, when someone seduces your seventeen-year-old. He knows the pain you live with when you come home to a quiet apartment where the only children are visitors, when you hear that your former husband and his new wife were sealed in the temple last week, when your fiftieth wedding anniversary rolls around and your husband has been dead for two years. He knows all that. He's been there. He's been lower than all that. He's not waiting for us to be perfect. Perfect people don't need a Savior. He came to save his people in their imperfections. He is the Lord of the living, and the living make mistakes. He's not embarrassed by us, angry at us, or shocked. He wants us in our brokenness, in our unhappiness, in our guilt and our grief. You know that people who live above a certain latitude and experience very long winter nights can become depressed and even suicidal, because something in our bodies requires whole spectrum light for a certain number of hours a day. Our spiritual requirement for light is just as desperate and as deep as our physical need for light. Jesus is the light of the world. We know that this world is a dark place sometimes, but we need not walk in darkness. The people who sit in darkness have seen a great light, and the people who walk in darkness can have a bright companion. We need him, and He is ready to come to us, if we'll open the door and let him.

All along I have the answer, it's written in my face, this is neither bad luck nor curse, but a show of God's grace. I may sometimes know why, I may sometimes feel doubt, but I'm not here to fit in, I was born to stand out.

I'd assume love was safe, like ordering the same thing at a restaurant every single time. I didn't realize that it could be a greasy roadside sandwich and vomiting, followed by a conversation that made time slow down and my heart speed up.

they began to kill the innocents in their mother’s womb because these babies are hindering them from achieving what they believe is their self-realization through pleasures, a false freedom, and worldly success. Then they eliminate sick people; then the handicapped, for instance those with Down syndrome, and so on. This is the path of the new dictatorship, patterned after the Nazi dictatorship in Germany and the Communist dictatorship in the Soviet Union. This is a process which leads ultimately to an exasperated egoism, to a cruel and inhuman society.

The idea of living with someone scares me senseless. I‘ve done it before for five years, and I shut down to cope with it. I don‘t want to give up myself again. I hope to find someone who is happy just to continue “as is” without expectations. (Kes)

Every one of us is like the pieces of a puzzle. Each one unique and with our own special place where only we can fit, and without every one of us, the picture wouldn’t be complete.

Life is conceived as a vast supermarket through which one moves with one’s shopping trolley, fetching down ways of life from shelves marked “Existential choices.

Begin with the soft smelted upturned heart-shaped mouth made for smiling a smile kept for kindness, tenderness, incapable of malice. Am I going too fast for you? The almond eyes see out through their sleepy epicanthic fold. Trusting and calm, if a flicker from slowness, a further flicker from stupidity. Settled in slow-motion beauty, heart-breaking beauty.

The first problem of any kind of even limited success is the unshakable conviction that you are getting away with something, and that at any moment now they will discover you. It's Imposter Syndrome, something my wife Amanda christened The Fraud Police. In my case, I was convinced that there would be a knock on the door, and a man with a clipboard (I don't know why he carried a clipboard, in my head, but he did) would be there, to tell me it was all over, and they had caught up with me, and now I would have to go and get a real job, one that didn't consist of making things up and writing them down, and reading books I wanted to read.

More often than not, a statist's argument against Anarchism boils down to an unwillingness to take control and responsibility for their own lives, actions, and communities. The sad truth is that the human animal has been domesticated to the point where it actually fears Liberty.

I sat on the grocery store floor for a half hour, reading the labels on all the boxes. I was upset Sydney was at risk for something called toxic shock syndrome, so I followed an old lady down the aisle and she showed me female incontinence products. I thought they did the same job. Turns out I was dead wrong.

The last day i was home i took the rental car up old 14 behind the Sandia Mountains. as i drove north toward Santa Fe past Madrid I rolled the window down halfway and let the cold, brisk, February air come into the car. I smelled the pinon trees and the damp earth. The Gray came over me. My life flashed through my heart in one deep rush of feeling. When I made the turn around the mountain to the west, the mesas and valleys spread out before me under the orange and gold horizon. The sun hit me like a wave that flooded out the past and dissolved any idea of the future, and I felt okay and whole for about twenty minutes.

The label neurodiverse includes everyone from people with ADHD, to Down Syndrome, to Obsessive-Compulsive Disorder, to Borderline Personality Disorder. It also includes people with brain injuries or strokes, people who have been labeled “low intelligence,” and people who lack any formal diagnosis, but have been pathologized as “crazy” or “incompetent” throughout their lives. As Singer rightly observed, neurodiversity isn’t actually about having a specific, catalogued “defect” that the psychiatric establishment has an explanation for. It’s about being different in a way others struggle to understand or refuse to accept.

The life of a seamstress is no smaller than the life of a queen, the life of a child with Down syndrome no less filled with promise than the life of a philosopher, because the only significant measure of your life is the positive effect you have on others, either by conscious acts of will or by unconscious example.

How to be there for someone with depression or anxiety 1. Know that you are needed, and appreciated, even if it seems you are not. 2. Listen. 3. Never say ‘pull yourself together’ or ‘cheer up’ unless you’re also going to provide detailed, foolproof instructions. (Tough love doesn’t work. Turns out that just good old ‘love’ is enough.) 4. Appreciate that it is an illness. Things will be said that aren’t meant. 5. Educate yourself. Understand, above all, that what might seem easy to you –going to a shop, for instance –might be an impossible challenge for a depressive. 6. Don’t take anything personally, any more than you would take someone suffering with the flu or chronic fatigue syndrome or arthritis personally. None of this is your fault. 7. Be patient. Understand it isn’t going to be easy. Depression ebbs and flows and moves up and down. It doesn’t stay still. Do not take one happy/ bad moment as proof of recovery/ relapse. Play the long game. 8. Meet them where they are. Ask what you can do. The main thing you can do is just be there. 9. Relieve any work/ life pressure if that is doable. 10. Where possible, don’t make the depressive feel weirder than they already feel. Three days on the sofa? Haven’t opened the curtains? Crying over difficult decisions like which pair of socks to wear? So what. No biggie. There is no standard normal. Normal is subjective. There are seven billion versions of normal on this planet.

It was the reference to Down’s syndrome that most upset him. Mary described it as an ‘awful sickness’. It wasn’t. It was a condition, not an illness. What sort of woman could see it as a threat to her own bloodline? Had she really pulled up the drawbridge on her son’s marriage simply to protect future grandchildren from

Since Roe v. Wade, abortion on demand has become engrained in American society. Not only have we killed at least fifty five million Americans in the womb, and emerging from the womb (not including under-reported abortion estimates), we also now kill over 90% of all Down Syndrome babies, solely because of their disability.

[Patricia Highsmith] was an extremely unbalanced person, extremely hostile and misanthropic and totally incapable of any kind of relationship, not just intimate ones. I felt sorry for her, because it wasn't her fault. There was something in her early days or whatever that made her incapable. She drove everybody away and people who really wanted to be friends ended up putting the phone down on her. It seemed to me as if she had to ape feelings and behaviour, like Ripley. Of course sometimes having no sense of social behaviour can be charming, but in her case it was alarming. I remember once, when she was trying to have a dinner party with people she barely knew, she deliberately leaned towards the candle on the table and set fire to her hair. People didn't know what to do as it was a very hostile act and the smell of singeing and burning filled the room.

A syndrome is small, portable, not weighed down by theory, episodic. You can explain something with it and then discard it. A disposable instrument of cognition. Mine is called Recurrent Detoxification Syndrome. Without the bells and whistles, its description boils down to the insistence of one’s consciousness on returning to certain images, or even the compulsive search for them. It is a variant of the Mean World Syndrome, which has been described fairly exhaustively in neuropsychological studies as a particular type of infection caused by the media. It’s quite a bourgeois ailment, I suppose. Patients spend long hours in front of the TV, thumbing at their remote controls through all the channels till they find the ones with the most horrendous news: wars, epidemics, and disasters. Then, fascinated by what they’re seeing, they can’t tear themselves away. The symptoms themselves

Writing isn’t easy. Writing means telling the truth when I want to lie.

Overstimulated. Light, sound, touch, all had been amped up. He closed his eyes to shut out the excess information and tried to get his senses to slow down.

I remember a woman, the mother of a child with Down syndrome, had come to talk to us about the manner in which the doctors and geneticists had discussed her daughter’s postnatal diagnosis with her, which ranged from heartless to clueless. But then, she said, on the day she and her baby were being discharged, the attending resident had come to say goodbye to them. “Enjoy her,” he had said to this woman. Enjoy her: No one had ever told her that she might delight in her baby, that her baby might be a source not of troubles but of pleasure.

But when you harbor an inner script that treats you like the enemy, it doesn't allow you to soar for very long. Doubts nibble at the edges of your thoughts until they're the only voice left. Imposter syndrome secures its triumph and ushers in an era of self-sabotage. Then the carnival shuts down, packs up, moves to another town. And you're alone, hiding in the dark.

You are gonna shoot me," he says. "One day." He's still holding Lindsay's hand, he's looking down at where their fingers are wound together and not at Lindsay's face, but his voice is clear. "I ain't thick. I know you'll get sick of me. You can't just let me go, I know too much, you'd be freaked out forever in case I snitched. You'll get proper sick of me one day, not just annoyed, and then you'll shoot me. It's okay." "I won't get sick of you," Lindsay says. He feels numb and far away, as if its somebody else talking, and almost like he's going to throw up, a sort of lurch in his stomach like when you're at the top of the the Angel tube station escalator and somebody a bit too eager to get on the train shoves you from behind. "Yeah you will. I'm gonna be with you til I die, though. Least I can say that and know its true, how many people can do that? Bit romantic, really. If you squint, and look at it sideways.

The resistance of the medical profession to dietary carbohydrate restriction in the treatment of metabolic syndrome and, more important, to its most obvious risk, diabetes, I find incomprehensible.

The particular kind of rest you need when you have adrenal fatigue comes not so much from lying down, but from standing up for yourself, and from removing or minimizing the harmful stresses in your life.

I think what I really want is to treat life less like a war. Wouldn't we have less Imposter Syndrome and fewer actual imposters if we just lowered our standards a bit? Modern productivity dogma encourages us to act fast, and milk our exceptionalism for all it's worth. Under that kind of pressure, perhaps the truest rebellion is to embrace our ordinariness. In everyday life, if we could not only tolerate the discomfort, but wholeheartedly embrace our own lack of expertise, then we might have a far better chance of showing others the same grace. Then perhaps life might feel, at the very least, less agitating, at most, we might even find peace. How’s this? Let’s stoop below average at 50% of all we do. We’ll relish it, the commonness. Next time we have a question, let’s hold our for as long as we humanly can before googling the answer. It’ll be erotic, like edging before a climax. It’s quite nice, I am learning, just to wonder indefinitely. To never have certain answers. To sit down, be humble, and not even dare to know

Most anyone who has endeavored to maintain the habit of prayer, or making art, or regular exercise...knows the syndrome well. When I sit down to pray or write, a host of thoughts arise. I should call to find out how so-and-so is doing. I should dust and organize my desk, because I will get more work done in a neater space. While I'm at it, I might as well load and start the washing machine. I may truly desire to write, but as I am pulled to one task after another I lose the ability to concentrate on the work at hand. Any activity, even scrubbing the toilet, seems more compelling than sitting down to face the blank page.

In 1945, Yvonne established an Anne de Gaulle Foundation for Down’s syndrome children in a château bought for the purpose outside Paris, and, after his daughter’s death in 1948, de Gaulle kept her framed photograph with him.

One of the problems with shutting down feeling is that we begin to live in our heads. We tell ourselves a story about what we think we’re feeling or what we think we should be feeling rather than feeling our genuine emotions and allowing words to grow out of them so we can accurately describe our inner experience. When we can feel our feelings and then translate them into language, we can use our reasoning ability to play a role in regulating our emotional experience.

HUMAN GIVER SYNDROME In Down Girl: The Logic of Misogyny, philosopher Kate Manne describes a system in which one class of people,7 the “human givers,” are expected to offer their time, attention, affection, and bodies willingly, placidly, to the other class of people, the “human beings.”8 The implication in these terms is that human beings have a moral obligation to be or express their humanity, while human givers have a moral obligation to give their humanity to the human beings. Guess which one women are.

We decided it would be best to just say that our new baby was a girl, and if anyone asked how she was doing, we would then explain, “She has a heart issue, which is very common for babies born with Down syndrome.” I told the older boys, “Guys, the world often defines a person as ‘perfect’ when he or she is pretty, handsome, athletic, intelligent, and wealthy. Yet, these are not the qualities that God judges us on. He looks at our souls because it is the pure souls that experience the eternal glory of heaven.

Not comprehending things the way other people do is fine in academia because we can usually find our own methods, but in social situations, this same tendency plays out differently—we can‘t always impose our own rules and priorities on others. We can‘t research people in everyday conversation the way we research information from books. It is not uncommon for us, when we‘re young, to ask too many questions of others, which makes them uncomfortable. If we could set the tone, we would probably be more comfortable, but we can‘t so we shut down.

Sepsis stimulates a catastrophic response from the immune system called SIRS for Systemic Inflammatory Response Syndrome. The acronym sounds polite but the reality of SIRS is not. At the late stages of sepsis, fluid from the blood stream moves into the body’s tissues, leaving a reduced volume of blood in the arteries and veins. Due to this decrease in volume, the patient’s blood pressure drops, and can keep dropping until there isn’t enough pressure to send blood to every part of the body. When that happens, organs begin to shut down and die. To

I called it the San Clemente Syndrome. Today's Basilica of San Clemente is built on the site of what once was a refuge for persecuted Christians. The home of the Roman consul Titus Flavius Clemens, it was burnt down during Emperor Nero's reign. Next to its charred remains, in what must have been a large, cavernous vault, the Romans built an underground pagan temple dedicated to Mithras, God of the Morning, Light of the World, over whose temple the early Christians built another church, dedicated -coincidentally or not, this is a matter to be further excavated to another Clement, Pope St. Clement, on top of which came yet another church that burnt down and on the site of which stands today's basilica. And the digging could go on and on. Like the subconscious, like love, like memory, like time itself, like every single one of us, the church is built on the ruins of subsequent restorations, there is no rock bottom, there is no first anything, no last anything, just layers and secret passageways and interlocking chambers, like the Christian Catacombs, and right along these, even a Jewish Catacomb.

I definitely think mothers of children with disabilities have to have extraordinary courage every day...Because we all know our children have value and worth and potential, but the everyday world sometimes doesn’t.' —Linda Strobel in Up: A Love Letter to the Down Syndrome Community

In 1996, the artist Gunter Demnig started laying stolpersteine, or "stumbling blocks" -- cobblestone-sized, brass memorials -- in front of houses where victims of the Nazis used to live. Now in over 800 German towns and villages, they make the number of victims palpable: In some streets there are stolpersteine in front of every other house, sometimes with a single name, sometimes with the names of an entire family. On these streets it would have been glaringly obvious that some neighbors were missing: the Jewish family, the girl with Down syndrome, the homosexual, the communist.

I also thought about that seminar classmate on Adam's ninth birthday. Adam had insisted on going to a pizza-and-games arcade for his party. The only person he'd invited besides his sisters was someone I'll call Lonnie, whom Adam claimed to be his girlfriend. Although I had often heard Adam sing about Lonnie, I had never met her, or seen Adam interact with any girl. I was afraid that he would start humping her leg the second she came in range. These were fears I'd sustained since before he was born; I though all people with Down syndrome were grossly overaffectionate. I was grossly wrong.

Kristen needs time in the morning to shower and get ready for work. Compared to the more advanced topics on the list, such as Be more present in our family’s moments and Take a break from your own head once in a while, the shower-time thing seemed relatively easy to master. I’d start there. Normally on workdays, Kristen would wake up at five thirty or six, a few minutes before the kids, and try to take a quick shower. Inevitably the shower would wake up Emily because her room was next to our bathroom. Emily would toddle past me, sound asleep in my bed, to join Kristen in the bathroom until she finished showering. Then they’d wake up Parker and go downstairs for breakfast. After breakfast (so I’m told) Kristen would play with the kids before returning to our bathroom to finish getting ready, while they crowded her and played at her feet. All I ever saw of this process was the tail end, when Kristen would emerge from the bathroom to kiss me good-bye and tell me she was taking the kids next door to Mary’s. That’s when my day would begin. How can I make time for her to get ready without interfering with my own routine? I wondered, sitting down on the edge of our bed. Maybe she could wake up a half hour earlier, say five A.M.? I didn’t think that would work.

Oh! I see it!’ I say. ‘I’m sitting, yes, I’m definitely sitting down on a chair with, let’s see, with my dad in front of me, who’s suddenly developed symptoms of Nutcase Syndrome, and… oh wait, that’s the here and now.’ I’m about to push his hands away from me. ‘I’m starting to think it’s you who needs to go to the hos-

I always got the feeling with John Paul that if he could have narrowed down the people he met and blessed those he loved the most, they would not be cardinals, princes, or congressman, but nuns from obscure convents and Down syndrome children, especially the latter. Because they have suffered, and because in some serious and amazing way the love of God seems more immediately available to them. Everyone else gets themselves tied up in ambition and ideas and bustle, all the great distractions, but the modest and unwell are so often unusually open to this message: God loves us, his love is all around us, he made us to love him and be happy

Most notably, perhaps, children with Down syndrome have an extraordinary sweetness of temperament, as if in inheriting an extra chromosome they had acquired a concomitant loss of cruelty and malice (if there is any doubt that genotypes can influence temperament or personality, then a single encounter with a Down child can lay that idea to rest).

The three rules for getting control of your diet. Rule 1. If you’re OK, you’re OK. Rule 2. If you want to lose weight: Don’t eat. If you have to eat, don’t eat carbs. If you have to eat carbs, eat low-glycemic index carbs. Rule 3. If you have diabetes or metabolic syndrome, carbohydrate restriction is the “default” approach, that is, the one to try first.

Look at us,” he said. His speech was difficult to understand, thick and slow as a warped record. His two friends in the picture had Down’s syndrome. All three of them looked extremely pleased with themselves. I admired the picture and then handed it back to him. He stopped, so I stopped, too. He pointed to his own image. “That,” he said, “is one cool man.

It was something I thought of when I was talking with my sister,” he says. Derek’s sister teaches children born with Down syndrome. “She mentioned that some parents don’t want to push their kids too much, because they’re afraid of exposing them to the possibility of failure. The parents mean well, but they’re keeping their kids from reaching their full potential when they coddle them.

I think one of the things I’ve learned as a writer...is that speech is a form of power in this world. As a writer, being able to articulate what other people may be feeling but perhaps struggle to put into words themselves, it is valued. But I also believe we—all of us—communicate in silence, in energy, in a love that extends from our hearts. And, to me, this is another form of inner power.

To this day, I am embarrassed to admit that I still deeply struggle with get-yo-ass-up syndrome. At least back then, my dad was still down to be my human alarm clock. When all other tactics failed to get the job done- tickling me, pulling the covers off of my virtually comatose body, shouting- my dad made up a wake-up song that he sang to me nearly every morning for sixteen years: "Lainey Flainey, give me your answer true. I'm half crazy over the likes of you." He'd saunter into my room and sit on the edge of my bed, tap, tap, tapping my tiny body to the beat until I finally woke up. Looking back, it was the most loving, patient act of parenting in the universe. Of course, at the time, it was simply annoying as hell. "And we're off like a herd of turtles!" he'd say. Every. Single. Day.

They laughed good-humoredly, mocking the sense of placelessness that comes when a child’s development is not sheltered under the great umbrella of the bell curve. In the big world and even in this little red schoolhouse, Nathaniel was not an average kid but an outlier, at the map’s edge where ships fall off the flat Earth and dragons roam. Suddenly I wished for a child with Down syndrome so he would not be peerless, in a class by himself.

Maslow used an apt term for this evasion of growth, this fear of realizing one's own fullest powers. He called it the "Jonah Syndrome." He understood the syndrome as the evasion of the full intensity of life: We are just not strong enough to endure more! It is just too shaking and wearing. So often people in...ecstatic moments say, "It's too much," or "I can't stand it," or "I could die"....Delirious happiness cannot be borne for long. Our organisms are just too weak for any large doses of greatness.... The Jonah Syndrome, then, seen from this basic point of view, is "partly a justified fear of being torn apart, of losing control, of being shattered and disintegrated, eve of being killed by the experience." And the result of this syndrome is what we would expect a weak organism to do: to cut back the full intensity of life: For some people this evasion of one's own growth, setting low levels of aspiration, the fear of doing what one is capable of doing, voluntary self-crippling, pseudo-stupidity, mock-humility are in fact defenses against grandiosity... It all boils down to a simple lack of strength to bear the superlative, to open oneself to the totality of experience-an idea that was well appreciated by William James and more recently was developed in phenomenological terms in the classic work of Rudolf Otto. Otto talked about the terror of the world, the feeling of overwhelming awe, wonder, and fear in the face of creation-the miracle of it, the mysterium tremendum et fascinosum of each single thing, of the fact that there are things at all. What Otto did was to get descriptively at man's natural feeling of inferiority in the face of the massive transcendence of creation; his real creature feeling before the crushing negating miracle of Being.

blood sugar values go down, blood pressure drops, chronic pain decreases or disappears, lipid profiles improve, inflammatory markers improve, energy increases, weight decreases, sleep is improved, IBS [irritable bowel syndrome] symptoms are lessened, etc. Medication is adjusted downward, or even eliminated, which reduces the side-effects for patients and the costs to society. The results we achieve with our patients are impressive and durable.

Migraines are described as “one of the most common” pain syndromes, affecting as much as 12 percent of the population.63 That’s common? How about menstrual cramps, which plague up to 90 percent of younger women?64 Can ginger help? Even just one-eighth of a teaspoon of ginger powder three times a day dropped pain from an eight to a six on a scale of one to ten, and down further to a three in the second month.65 And these women hadn’t been taking ginger all month; they started the day before their periods began, suggesting that even if it doesn’t seem to help much the first month, women should try sticking with it. What about the duration of pain? A quarter teaspoon of ginger powder three times a day was found to not only drop the severity of menstrual pain from about seven down to five but decrease the duration from a total of nineteen hours in pain down to about fifteen hours,66 significantly better than the placebo, which were capsules filled with powdered toast. But women don’t take bread crumbs for their cramps. How does ginger compare to ibuprofen? Researchers pitted one-eighth of a teaspoon of powdered ginger head-to-head against 400 mg of ibuprofen, and the ginger worked just as effectively as this leading drug.67 Unlike the drug, ginger can also reduce the amount of menstrual bleeding, from around a half cup per period down to a quarter cup.68 What’s more, ginger intake of one-eighth of a teaspoon twice daily started a week before your period can yield a significant drop in premenstrual mood, physical, and behavioral symptoms.69 I like sprinkling powdered ginger on sweet potatoes or using it fresh to make lemon-ginger apple chews as an antinausea remedy. (Ever since I was a little kid, I’ve suffered from motion sickness.) There is an array of powerful antinausea

What time did you finally put the book down last night?” Lindsey glanced at the floor, where the book she’d been reading had landed when she’d fallen asleep. “One thirty, maybe two.” “In the morning?” Sully asked. He ran a hand through his reddish brown hair, making the curly waves stand on end. “I was suffering from OMC syndrome,” she said. “OMC, is that some sort of insomnia?” “Sort of. It stands for one more chapter.” “Book nerd,” Sully teased.

Failures weigh people down. Writing reports of all the cases I was unable to solve, however, had helped me to tell stories, or at least get them down on paper, as they say. Whether I was obeying or taming language is not important.... Sometimes failures push us to open the door of a run-down old house, to clean the dust off the unused furniture and find a drawer where an old typewriter hides. Failures force us to reflect, and reflection, with any luck, may lead us to a coastal city and a pile of blank pages.

The breaking point for Foege came in 1983, after the CDC’s researchers established a connection between aspirin and Reye’s syndrome in children. When given to children suffering from flu or measles, aspirin could trigger swelling in the liver and the brain and, in rare cases, death. Companies that manufactured aspirin petitioned the White House. “The White House called and told us to cease and desist,” recalled Foege. “Do a new study.” The aspirin makers had been able to force the CDC to scrap its findings and slow down science.

Let’s say you are 31 and you undergo the cell-free fetal DNA screening. With a good result on this, the baby’s risk of having Down syndrome is around 1 in 100,000. The risk of miscarriage from the amniocentesis or CVS test is around 1 in 800. What you need to decide for yourself is whether having a baby with Down syndrome unexpectedly would be more than 125 times worse than having a miscarriage (that is, 100,000 divided by 800). If yes, then skip right to the invasive test—probably CVS given the timing. If no, then stick with the noninvasive screen.

Ionizing radiation takes three principal forms: alpha particles, beta particles, and gamma rays. Alpha particles are relatively large, heavy, and slow moving and cannot penetrate the skin; even a sheet of paper could block their path. But if they do manage to find their way inside the body by other means—if swallowed or inhaled—alpha particles can cause massive chromosomal damage and death. Radon 222, which gathers as a gas in unventilated basements, releases alpha particles into the lungs, where it causes cancer. Polonium 210, a powerful alpha emitter, is one of the carcinogens in cigarette smoke. It was also the poison slipped into the cup of tea that killed former FSB agent Alexander Litvinenko in London in 2006. Beta particles are smaller and faster moving than alpha particles and can penetrate more deeply into living tissue, causing visible burns on the skin and lasting genetic damage. A piece of paper won’t provide protection from beta particles, but aluminum foil—or separation by sufficient distance—will. Beyond a range of ten feet, beta particles can cause little damage, but they prove dangerous if ingested in any way. Mistaken by the body for essential elements, beta-emitting radioisotopes can become fatally concentrated in specific organs: strontium 90, a member of the same chemical family as calcium, is retained in the bones; ruthenium is absorbed by the intestine; iodine 131 lodges particularly in the thyroid of children, where it can cause cancer. Gamma rays—high-frequency electromagnetic waves traveling at the speed of light—are the most energetic of all. They can traverse large distances, penetrate anything short of thick pieces of concrete or lead, and destroy electronics. Gamma rays pass straight through a human being without slowing down, smashing through cells like a fusillade of microscopic bullets. Severe exposure to all ionizing radiation results in acute radiation syndrome (ARS), in which the fabric of the human body is unpicked, rearranged, and destroyed at the most minute levels. Symptoms include nausea, vomiting, hemorrhaging, and hair loss, followed by a collapse of the immune system, exhaustion of bone marrow, disintegration of internal organs, and, finally, death.

Are you calling me weak?' 'No.' Mira squeezes my hand. 'Just... fragile.' 'That's not any better.' Dragons don't bond fragile women. They incinerate them. 'So she's small.' Mom scans me up and down, taking in the generous fit of the cram belted tunic and pants I selected this morning for my potential execution. I snort. 'Are we just listing my faults now?' 'I never said it was a fault.' Mom turns to my sister. 'Mira, Violet deals with more pain before lunch than you do in an entire week. If any of my children is capable of surviving the Rider's Quadrant, it's her.

16Most anyone who has endeavored to maintain the habit of prayer, or making art, or regular exercise...knows the syndrome well. When I sit down to pray or write, a host of thoughts arise. I should call to find out how so-and-so is doing. I should dust and organize my desk, because I will get more work done in a neater space. While I'm at it, I might as well load and start the washing machine. I may truly desire to write, but as I am pulled to one task after another I lose the ability to concentrate on the work at hand. Any activity, even scrubbing the toilet, seems more compelling than sitting down to face the blank page.

Why is it that women are the only ones who will write perfect men into fiction? It's strange. If a man portrayed his fictional men as archangels, the feminists would throw back their heads and howl, "UNFAIR!" but we women will create our own Mr. Darcy's and Mr. Knightley's and defy anyone who would point out their unrealistic points. The men aren't the ones crazy about Pride and Prejudice. Obviously they don't find perfect men realistic and honest enough to bother reading about. We don't write perfect women characters, do we? No. Our women all have bad tempers, or resentful hearts, or scabby pasts, or hidden fears--things that make them real. It's because we're easy on ourselves and aren't trying to boast perfection because we know we don't measure up. Then why do we hold men to a different standard?..... I'd caution all writers to make sure that your male "hero" in your story has his own flaws. You don't want a one-dimensional character. You don't want a perfect man that will drive away other men from reading the book. Look to the men in your life. The men around you. Look to your brothers and fathers and pastors and neighbors. Your uncles and the guy down the street. Goodness--look to Taylor the Latte Boy if you must, but let's cast aside the Perfect-Man syndrome.

In 1996, when Senator Bob Dole runs against President Clinton, it’s a historic moment for people with disabilities. No one with a visible disability has run for the high office since Franklin Roosevelt—and unlike Roosevelt, Dole is forthcoming about his impairment (an arm injured in wartime). It sets a political conundrum for some in the movement: Dole may be one of us, and may have been an early supporter of the ADA, but aren’t Democrats better for disenfranchised minorities? That same year, a woman with Down syndrome becomes the first person with that diagnosis to receive a heart and lung transplant. She’d been turned down at first, but hospital administrators cave to activists. These and other

Of that first decade, Neil said I would have this recurring fantasy in which there would be a knock on the door, and I would go down, and there would be somebody wearing a suit – not an expensive suit, just the kind of suit that showed they had a job – and they would be holding a clipboard, and they'd have a paper on the clipboard, and I'd open the door and they'd say, „Hello, excuse me, I'm afraid I am here on official business. Are you Neil Gaiman?” And I would say yes. „Well, it says here that you are a writer and that you don't have to get up in the morning at any particular time, that you just write each day as much you want.” And I'd go „That's right.” "And that you enjoy writing. And it says here that all the books you want – they are just sent to you and you don't have to buy them. And films: it says here that you just go to see films. If you want to see them you just call up the person who runs the films." And I say, „Yes, that's right.” And that people like what you do and they give you money for just writing things down." And I'd say yes. And he'd say, „Well, I'm afraid we are on to you. We've caught up with you. And I'm afraid you are now going to have to go out and get a proper job.” At which point in my fantasy my heart would always sink, and I'd go, „Okay,” and I'd go and buy a cheap suit and I'd start applying to real jobs. Because once they've caught up with you, you can't argue with this: they've caught up with you. So that was the thing in my head.

Premenstrual syndrome (PMS) is a collection of symptoms that can include among other things: mood swings, anxiety, breast tenderness, bloating, acne, headaches, stomach pain and sleep problems. PMS affects 90% of women, but is chronically under-studied: one research round-up found five times as many studies on erectile dysfunction than on PMS.88 And yet while a range of medication exists to treat erectile dysfunction89 there is very little available for women, to the extent that over 40% of women who have PMS don’t respond to treatments currently available. Sufferers are still sometimes treated with hysterectomies; in extreme cases, women have tried to kill themselves.90 But researchers are still being turned down for research grants on the basis that ‘PMS does not actually exist’.91

I may appear to suffer from some sort of compulsive repetition syndrome, but these rituals are important to me. I have many places where I sit and think, “I have been here before, I am here now, and I will be here again.” Sometimes, lost in reverie, I remember myself approaching across the same green, or down the same footpath, in 1962 or 1983, or many other times. Sometimes Chaz comes along on my rituals, but just as often I go alone. Sometimes Chaz will say she’s going shopping, or visiting a friend, or just staying in the room and reading in bed. “Why don’t you go and touch your bases?” she’ll ask me. I know she sympathizes. These secret visits are a way for me to measure the wheel of the years and my passage through life. Sometimes on this voyage through life we need to sit on the deck and regard the waves.

If at all possible, a boy should stay home with one of his parents or a close relative until about age three. Daycare of the institutional kind does not suit boys’ nature during these very early years. Many studies have shown that boys are more prone than girls to separation anxiety and to becoming emotionally shut down as a result of feeling abandoned. Also, a boy of this age may cope with his anxiety by becoming restless or aggressive. Experienced caregivers talk about the “sad/angry boy syndrome”—a little boy who feels abandoned and anxious and converts that into hitting and hurting behavior. He may carry this behavior into school and later life. Care by a loving relative is far better than an institutional situation for toddlers under three. Children under three need to spend the long days of childhood with people to whom they are very special.

It was a sad fact that the commonest complaint in the outpatient department was “Rasehn . . . libehn . . . hodehn,” literally, “My head . . . my heart . . . and my stomach,” with the patient’s hand touching each part as she pronounced the words. Ghosh called it the RLH syndrome. The RLH sufferers were often young women or the elderly. If pressed to be more specific, the patients might offer that their heads were spinning (rasehn yazoregnal) or burning (yakatelegnal ), or their hearts were tired (lib dekam), or they had abdominal discomfort or cramps (hod kurteth), but these symptoms were reported as an aside and grudgingly, because rasehn-libehn-hodehn should have been enough for any doctor worth his salt. It had taken Matron her first year in Addis to understand that this was how stress, anxiety, marital strife, and depression were expressed in Ethiopia—somatization was what Ghosh said the experts called this phenomenon. Psychic distress was projected onto a body part, because culturally it was the way to express that kind of suffering. Patients might see no connection between the abusive husband, or meddlesome mother-in-law, or the recent death of their infant, and their dizziness or palpitations. And they all knew just the cure for what ailed them: an injection. They might settle for mistura carminativa or else a magnesium trisilicate and belladonna mixture, or some other mixture that came to the doctor’s mind, but nothing cured like the marfey—the needle. Ghosh was dead against injections of vitamin B for the RLH syndrome, but Matron had convinced him it was better for Missing to do it than have the dissatisfied patient get an unsterilized hypodermic from a quack in the Merkato. The orange B-complex injection was cheap, and its effect was instantaneous, with patients grinning and skipping down the hill. T

Triglyceride-to-HDL Ratio After assessing each of these five biomarkers, there is one more step: calculate your triglyceride-to-HDL ratio to better understand insulin sensitivity. Simply divide your triglycerides by your HDL. Interestingly, studies have shown that this value correlates well with underlying insulin resistance. So even if you are unable to access a fasting insulin test, the triglyceride-to-HDL ratio can give you a general sense of where you’re at. According to Dr. Mark Hyman, “the triglyceride-to-HDL ratio is the best way to check for insulin resistance other than the insulin response test. According to a paper published in Circulation, the most powerful test to predict your risk of a heart attack is the ratio of your triglycerides to HDL. If the ratio is high, your risk for a heart attack increases sixteen-fold—or 1,600 percent! This is because triglycerides go up and HDL (or ‘good cholesterol’) goes down with diabesity.” Dr. Robert Lustig agrees: “The triglyceride-to-HDL ratio is the best biomarker of cardiovascular disease and the best surrogate marker of insulin resistance and metabolic syndrome.” In children, higher triglyceride-to-HDL is significantly correlated with mean insulin, waist circumferences, and insulin resistance. In adults, the ratio has shown a positive association with insulin resistance across normal weight and overweight people and significantly tracks with insulin levels, insulin sensitivity, and prediabetes. Perplexingly, the triglyceride-to-HDL ratio is not a metric used in standard clinical practice. If you remember one thing from this chapter, remember this: you need to know your insulin sensitivity. It can give you lifesaving clues about early dysfunction and Bad Energy brewing in your body, and is best assessed by a fasting insulin test, discussed below. Right now, this is not a standard test offered to you at your annual physical. I implore you to find a way to get a fasting insulin test or to calculate your triglyceride-to-HDL ratio every year. Do this for your children, as well. And take the steps outlined in the following chapters to ensure it does not start creeping up. RANGES: Range considered “normal” by standard criteria: none specified in standard criteria Optimal range: Anything above a ratio of 3 is strongly suggestive of insulin resistance. You want to shoot for less than 1.5, although lower is better. I recommend aiming for less than 1.

Over time, the active verbs of the Shema-recite, walk, talk, lie down, rise, bind, fix, write, all in the service of love-become too much for us to imagine, let alone perform. Our search for superpowers has created many of the most pressing problems of our time. The defining mental activity of our time is scrolling Our capacities of attention, memory, and concentration are diminishing; to compensate, we toggle back and forth between infinite feeds of news, posts, images, episodes - taking shallow hits of trivia, humor, and outrage to make up for the depths of learning, joy, and genuine lament that now feel beyond our reach. The defining illness of our time is metabolic syndrome, the chronic combination of high weight, high cholesterol, high blood pressure, and high blood sugar that is the hallmark of an inactive life. Our strength is atrophying and our waistline expanding, and to compensate, we turn to the superpowers of the supermarket with the aisles of salt and fat convincing our bodies’ reward systems, one bite at a time, that we have never been better in our life. The defining emotional challenge of our time is anxiety, the fear of what might be instead of the courageous pursuit of what could be. Once, we lived with allness of heart, with a boldness of quest that was too in love with the good to call off the pursuit when we encountered risk. Now we live as voyeurs, pursuing shadowy vestiges of what we desire from behind the one-way mirror of a screen, invulnerable but alone. And, of course, the soul is the plane of human ex- istence that our technological age neglects most of all. Jesus asked whether it was worth gaining the whole world at the cost of losing one's soul. But in the era of superpowers, we have not only lost a great deal of our souls-we have lost much of the world as well. We are rarely overwhelmed by wind or rain or snow. We rarely see, let alone name, the stars. We have lost the sense that we are both at home and on a pilgrimage in the vast, mysterious cosmos, anchored in a rich reality beyond ourselves. We have lost our souls without even gaining the world. So it is no wonder that the defining condition of our time is a sense of loneliness and alienation. For if human flourishing requires us to love with all our hearts, souls, minds, and strength, what happens When nothing in our lives develops those capacities? With what, exactly, will we love?

While the visual areas of the brain are active, other areas involved with smell, taste, and touch are largely shut down. Almost all the images and sensations processed by the body are self-generated, originating from the electromagnetic vibrations from our brain stem, not from external stimuli. The body is largely isolated from the outside world. Also, when we dream, we are more or less paralyzed. (Perhaps this paralysis is to prevent us from physically acting out our dreams, which could be disastrous. About 6 percent of people suffer from “sleep paralysis” disorder, in which they wake up from a dream still paralyzed. Often these individuals wake up frightened and believing that there are creatures pinning down their chest, arms, and legs. There are paintings from the Victorian era of women waking up with a terrifying goblin sitting on their chest glaring down at them. Some psychologists believe that sleep paralysis could explain the origin of the alien abduction syndrome.) The hippocampus is active when we dream, suggesting that dreams draw upon our storehouse of memories. The amygdala and anterior cingulate are also active, meaning that dreams can be highly emotional, often involving fear. But more revealing are the areas of the brain that are shut down, including the dorsolateral prefrontal cortex (which is the command center of the brain), the orbitofrontal cortex (which can act like a censor or fact-checker), and the temporoparietal region (which processes sensory motor signals and spatial awareness). When the dorsolateral prefrontal cortex is shut down, we can’t count on the rational, planning center of the brain. Instead, we drift aimlessly in our dreams, with the visual center giving us images without rational control. The orbitofrontal cortex, or the fact-checker, is also inactive. Hence dreams are allowed to blissfully evolve without any constraints from the laws of physics or common sense. And the temporoparietal lobe, which helps coordinate our sense of where we are located using signals from our eyes and inner ear, is also shut down, which may explain our out-of-body experiences while we dream. As we have emphasized, human consciousness mainly represents the brain constantly creating models of the outside world and simulating them into the future. If so, then dreams represent an alternate way in which the future is simulated, one in which the laws of nature and social interactions are temporarily suspended

To their surprise, they found that dopamine actively regulates both the formation and the forgetting of new memories. In the process of creating new memories, the dCA1 receptor was activated. By contrast, forgetting was initiated by the activation of the DAMB receptor. Previously, it was thought that forgetting might be simply the degradation of memories with time, which happens passively by itself. This new study shows that forgetting is an active process, requiring intervention by dopamine. To prove their point, they showed that by interfering with the action of the dCA1 and DAMB receptors, they could, at will, increase or decrease the ability of fruit flies to remember and forget. A mutation in the dCA1 receptor, for example, impaired the ability of the fruit flies to remember. A mutation in the DAMB receptor decreased their ability to forget. The researchers speculate that this effect, in turn, may be partially responsible for savants’ skills. Perhaps there is a deficiency in their ability to forget. One of the graduate students involved in the study, Jacob Berry, says, “Savants have a high capacity for memory. But maybe it isn’t memory that gives them this capacity; maybe they have a bad forgetting mechanism. This might also be the strategy for developing drugs to promote cognition and memory—what about drugs that inhibit forgetting as a cognitive enhancers?” Assuming that this result holds up in human experiments as well, it could encourage scientists to develop new drugs and neurotransmitters that are able to dampen the forgetting process. One might thus be able to selectively turn on photographic memories when needed by neutralizing the forgetting process. In this way, we wouldn’t have the continuous overflow of extraneous, useless information, which hinders the thinking of people with savant syndrome. What is also exciting is the possibility that the BRAIN project, which is being championed by the Obama administration, might be able to identify the specific pathways involved with acquired savant syndrome. Transcranial magnetic fields are still too crude to pin down the handful of neurons that may be involved. But using nanoprobes and the latest in scanning technologies, the BRAIN project might be able to isolate the precise neural pathways that make possible photographic memory and incredible computational, artistic, and musical skills. Billions of research dollars will be channeled into identifying the specific neural pathways involved with mental disease and other afflictions of the brain, and the secret of savant skills may be revealed in the process. Then it might be possible to take normal individuals and make savants out of them. This has happened many times in the past because of random accidents. In the future, this may become a precise medical process.