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On the other hand, when you mismanage your genes with poor dietary habits or chronic exercise patterns, you will likely suffer from obesity (through the chronic overproduction of insulin), fatigue (poor sleep habits disturbing optimal hormone balance), and systemic inflammation and burnout (chronic production of “fight or flight” hormones in the face of unrelenting environmental stressors).
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Mark Sisson (The Primal Blueprint 21-Day Total Body Transformation: A complete, step-by-step, gene reprogramming action plan)