Parkinson's Day Quotes

The other day as I was stepping out of Star Grocery on Claremont Avenue with some pork ribs under my arm, the Berkeley sky cloudless, a smell of jasmine in the air, a car driving by with its window rolled down, trailing a sweet ache of the Allman Brothers' "Melissa," it struck me that in order to have reached only the midpoint of my life I will need to live to be 92. That's pretty old. If you live to be ninety-two, you've done well for yourself. I'd like to be optimistic, and I try to take care of my health, but none of my grandparents even made it past 76, three killed by cancer, one by Parkinson's disease. If I live no longer than any of them did, I have at most thirty years left, which puts me around sixty percent of the way through my time. I am comfortable with the idea of mortality, or at least I always have been, up until now. I never felt the need to believe in heaven or an afterlife. It has been decades since I stopped believing-a belief that was never more than fitful and self-serving to begin with-in the possibility of reincarnation of the soul. I'm not totally certain where I stand on the whole "soul" question. Though I certainly feel as if I possess one, I'm inclined to disbelieve in its existence. I can live with that contradiction, as with the knowledge that my time is finite, and growing shorter by the day. It's just that lately, for the first time, that shortening has become perceptible. I can feel each tiny skyward lurch of the balloon as another bag of sand goes over the side of my basket.

The solution is really simple: Figure out what time you can carve out, what time you can steal, and stick to your routine. Do the work every day, no matter what. No holidays, no sick days. Don’t stop. What you’ll probably find is that the corollary to Parkinson’s Law is usually true: Work gets done in the time available.

An apple a day might have kept the doctor away prior to the industrialization of food growing and preparation. But, according to research compiled by the United States Drug Administration (USDA) today’s apple contains residue of eleven different neurotoxins—azinphos, methyl chloripyrifos, diazinon, dimethoate, ethion, omthoate, parathion, parathion methyl, phosalone, and phosmet — and the USDA was testing for only one category of chemicals known as organophosphate insecticides. That doesn’t sound too appetizing does it? The average apple is sprayed with pesticides seventeen times before it is harvested.

If you don’t drink coffee, you should think about two to four cups a day. It can make you more alert, happier, and more productive. It might even make you live longer. Coffee can also make you more likely to exercise, and it contains beneficial antioxidants and other substances associated with decreased risk of stroke (especially in women), Parkinson’s disease, and dementia. Coffee is also associated with decreased risk of abnormal heart rhythms, type 2 diabetes, and certain cancers.12, 13 Any one of those benefits of coffee would be persuasive, but cumulatively they’re a no-brainer. An hour ago I considered doing some writing for this book, but I didn’t have the necessary energy or focus to sit down and start working. I did, however, have enough energy to fix myself a cup of coffee. A few sips into it, I was happier to be working than I would have been doing whatever lazy thing was my alternative. Coffee literally makes me enjoy work. No willpower needed. Coffee also allows you to manage your energy levels so you have the most when you need it. My experience is that coffee drinkers have higher highs and lower lows, energywise, than non–coffee drinkers, but that trade-off works. I can guarantee that my best thinking goes into my job, while saving my dull-brain hours for household chores and other simple tasks. The biggest downside of coffee is that once you get addicted to caffeine, you can get a “coffee headache” if you go too long without a cup. Luckily, coffee is one of the most abundant beverages on earth, so you rarely have to worry about being without it. Coffee costs money, takes time, gives you coffee breath, and makes you pee too often. It can also make you jittery and nervous if you have too much. But if success is your dream and operating at peak mental performance is something you want, coffee is a good bet. I highly recommend it. In fact, I recommend it so strongly that I literally feel sorry for anyone who hasn’t developed the habit.

Scientists induced Parkinson’s in rats by killing the dopamine cells in their basal ganglia, and then forced half of them to run on a treadmill twice a day in the ten days following the “onset” of the disease. Incredibly, the runners’ dopamine levels stayed within normal ranges and their motor skills didn’t deteriorate. In one study on people with Parkinson’s, intensive activity improved motor ability as well as mood, and the positive effects lasted for at least six weeks after they stopped exercising.

Parkinson’s Law: If you have only one letter to write, it will take all day to do it. If you have twenty letters to write, you’ll get them done in one day.

COACHING TIPS • Give yourself permission to “waste” a little time. If you’re not spending 5 percent of your day building relationships, you’re doing something wrong. • Define your work hours and stick with them. Remember Parkinson’s Law: “Work expands to fill the time available.” This isn’t to say there won’t be times when you must work overtime, but if you’re consistently the last one left at the office, there’s something wrong with that picture.

This kind of pragmatism has become a hallmark of our psychological culture. In the mid-1990s, I described how it was commonplace for people to “cycle through” different ideas of the human mind as (to name only a few images) mechanism, spirit, chemistry, and vessel for the soul.14 These days, the cycling through intensifies. We are in much more direct contact with the machine side of mind. People are fitted with a computer chip to help with Parkinson’s. They learn to see their minds as program and hardware. They take antidepressants prescribed by their psychotherapists, confident that the biochemical and oedipal self can be treated in one room. They look for signs of emotion in a brain scan. Old jokes about couples needing “chemistry” turn out not to be jokes at all.

Once, on the road, Prim met a meditating sage who had spent most of his life on top of a flat rock. They had black bread and shared some ajash, as was custom. The sage was thankful, as the road was not very frequently traveled in those days and he was very near the point of starvation. During his conversation, he was delighted to learn of Prim’s extensive mastery of Empty Palms and the fifty five earthly purities. Delighted, and as payment for his meal, he taught Prim the meaning of watchfulness. This was the old breathing and cold-atum technique often used by warrior monks in those days. It ran through the following methodology: Build a tower, and make it impregnable. Make every stone so tightly sealed that no insect can squeeze through, no grain of sand can make it inside. Your tower must have no windows or doors. It must not accept passage by friend or foe. No weapon, no act of violence, and not one mote of love may penetrate its stony interior. “Why build the tower this way?” said Prim? “It will make you invincible,” said the sage, “This is the way of Ya-at slave monks. Their skin is like iron, and so are their hearts. They are inured to death and fear. Grief shall never find them, and neither shall weakness.” Prim thought a moment, and came upon a realization, for she was wise, obedient, and an excellent daughter. “If a man built a tower this way, he would quickly starve, no matter how strong he became.” The sage was even more delighted. “Yes,” he said, “There is a better way, and I will teach it to you: Once you have built your tower, you must deconstruct it, brick by brick, stone by stone. You must do it meticulously and carefully, so that while you leave no physical trace of it remaining, your tower is still built in your mind and your heart, ready to spring anew at a moment’s notice. You can enjoy the fresh air, and eat fine meals, and enjoy a good drink with your friends, but all the while your tower remains standing. You are both prisoner and warden. This is the hardest way, but the strongest.” Prim saw the wisdom in this, and quickly made to return to the road, but the sage stopped her before she left. “As you to your earlier remark,” the sage said, “The man who builds his tower but cannot take it apart again – that man is at the pinnacle of his strength. But that man will surely perish.” – Prim Masters the Road

It is possible that drinking three or four cups of coffee a day may protect against Alzheimer’s, as it was shown to protect against Parkinson’s.

Coffee If you don’t drink coffee, you should think about two to four cups a day. It can make you more alert, happier, and more productive. It might even make you live longer. Coffee can also make you more likely to exercise, and it contains beneficial antioxidants and other substances associated with decreased risk of stroke (especially in women), Parkinson’s disease, and dementia. Coffee is also associated with decreased risk of abnormal heart rhythms, type 2 diabetes, and certain cancers.12, 13 Any one of those benefits of coffee would be persuasive, but cumulatively they’re a no-brainer. An hour ago I considered doing some writing for this book, but I didn’t have the necessary energy or focus to sit down and start working. I did, however, have enough energy to fix myself a cup of coffee. A few sips into it, I was happier to be working than I would have been doing whatever lazy thing was my alternative. Coffee literally makes me enjoy work. No willpower needed. Coffee also allows you to manage your energy levels so you have the most when you need it. My experience is that coffee drinkers have higher highs and lower lows, energywise, than non–coffee drinkers, but that trade-off works. I can guarantee that my best thinking goes into my job, while saving my dull-brain hours for household chores and other simple tasks. The biggest downside of coffee is that once you get addicted to caffeine, you can get a “coffee headache” if you go too long without a cup. Luckily, coffee is one of the most abundant beverages on earth, so you rarely have to worry about being without it. Coffee costs money, takes time, gives you coffee breath, and makes you pee too often. It can also make you jittery and nervous if you have too much. But if success is your dream and operating at peak mental performance is something you want, coffee is a good bet. I highly recommend it. In fact, I recommend it so strongly that I literally feel sorry for anyone who hasn’t developed the habit. Pleasure

In 2017, researchers reconstructed the diets of Neanderthals, cousins of modern humans who went extinct approximately 50,000 years ago. They found that an individual with a dental abscess had been eating a type of fungus – a penicillin-producing mould – implying knowledge of its antibiotic properties. There are other less ancient examples, including the Iceman, an exquisitely well-preserved Neolithic corpse found in glacial ice, dating from around 5,000 years ago. On the day he died, the Iceman was carrying a pouch stuffed with wads of the tinder fungus (Fomes fomentarius) that he almost certainly used to make fire, and carefully prepared fragments of the birch polypore mushroom (Fomitopsis betulina) most probably used as a medicine. The indigenous peoples of Australia treated wounds with moulds harvested from the shaded side of eucalyptus trees. Ancient Egyptian papyruses from 1500 BCE refer to the curative properties of mould, and in 1640, the King’s herbalist in London, John Parkinson, described the use of moulds to treat wounds.

Parkinson’s Law dictates that a task will swell in (perceived) importance and complexity in relation to the time allotted for its completion. It is the magic of the imminent deadline. If I give you 24 hours to complete a project, the time pressure forces you to focus on execution, and you have no choice but to do only the bare essentials. If I give you a week to complete the same task, it’s six days of making a mountain out of a molehill. If I give you two months, God forbid, it becomes a mental monster. The end product of the shorter deadline is almost inevitably of equal or higher quality due to greater focus.

There’s a principle called Parkinson’s Law, after the man who coined it, Professor Cyril Northcote Parkinson. Parkinson’s Law goes like this: “Work expands to fill the time available for its completion.” Here’s how that looks when you apply it to the world of personal finances: Whatever I have, I spend. Actually, in today’s world it usually means something more like this: Whatever I have, I spend that—plus a little more. How hard is it to put aside a few dollars a day, or a little each week? Ridiculously easy. Yet most of us don’t do it. The United States has one of the highest per capita income rates in the world—and one of the lowest savings rates. Why is that?

In universities and pharmaceutical labs around the world, computer scientists and computational biologists are designing algorithms to sift through billions of gene sequences, looking for links between certain genetic markers and diseases. The goal is to help us sidestep the diseases we're most likely to contract and to provide each one of us with a cabinet of personalized medicines. Each one should include just the right dosage and the ideal mix of molecules for our bodies. Between these two branches of research, genetic and behavioral, we're being parsed, inside and out. Even the language of the two fields is similar. In a nod to geneticists, Dishman and his team are working to catalog what they call our "behavioral markers." The math is also about the same. Whether they're scrutinizing our strands of DNA or our nightly trips to the bathroom, statisticians are searching for norms, correlations, and anomalies. Dishman prefers his behavioral approach, in part because the market's less crowded. "There are a zillion people looking at biology," he says, "and too few looking at behavior." His gadgets also have an edge because they can provide basic alerts from day one. The technology indicating whether a person gets out of bed, for example, isn't much more complicated than the sensor that automatically opens a supermarket door. But that nugget of information is valuable. Once we start installing these sensors, and the electronics companies get their foot in the door, the experts can start refining the analysis from simple alerts to sophisticated predictions-perhaps preparing us for the onset of Parkinson's disease or Alzheimer's.

In universities and pharmaceutical labs around the world, computer scientists and computational biologists are designing algorithms to sift through billions of gene sequences, looking for links between certain genetic markers and diseases. The goal is to help us sidestep the diseases we're most likely to contract and to provide each one of us with a cabinet of personalized medicines. Each one should include just the right dosage and the ideal mix of molecules for our bodies. Between these two branches of research, genetic and behavioral, we're being parsed, inside and out. Even the language of the two fields is similar. In a nod to geneticists, Dishman and his team are working to catalog what they call our "behavioral markers." The math is also about the same. Whether they're scrutinizing our strands of DNA or our nightly trips to the bathroom, statisticians are searching for norms, correlations, and anomalies. Dishman prefers his behavioral approach, in part because the market's less crowded. "There are a zillion people looking at biology," he says, "and too few looking at behavior." His gadgets also have an edge because they can provide basic alerts from day one. The technology indicating whether a person gets out of bed, for example, isn't much more complicated than the sensor that automatically opens a supermarket door. But that nugget of information is valuable. Once we start installing these sensors, and the electronics companies get their foot in the door, the experts can start refining the analysis from simple alerts to sophisticated predictions-perhaps preparing us for the onset of Parkinson's disease or Alzheimer's.

lots of fruit and vegetables gives us all the vitamins we need. A lot is said about anti-oxidants these days. I do agree with the beneficial effects they might have on our health, and the possible need to have a good intake of them on a daily basis. As I have said, I eat a very healthy diet, with lots of fresh vegetables and fruit. I have never taken any anti-oxidant supplements, other than garlic pills, but am considering doing so. There is no proof that these anti-oxidants get through the blood-brain barrier, so they may not actually help us. I feel that a controlled double-blind study should be done on this subject. There

Continuation of Andy’s comments   Young, this is how I remember that incident:               When we entered the visitors’ lounge, that arrogant nitwit was smoking his pipe. The way he stared at you made me cringe. God only knows what would’ve happened if I weren’t with you. He would have molested you without reservation.               When he catechized your “formidable” counterproposal, which you had every right to stipulate, I was ready to punch that fool in the face. He was lucky I held back and did not allow my rage to cloud my better judgment. Otherwise, I would had knocked him out cold! I don’t think Dr. Dean Higgins would have appreciated a dead aristocrat on the school’s floor.☺               I was relieved when I read of his demise from Parkinson’s disease back in 1980. To this day, I’m still grateful for Uncle James’ timely warning to beware of this sanctimonious hypocrite.               My dear fella, I’m glad this despotic fascist is no longer living in our midst.               Andy XOXOXO

Again and again you will destroy yourselves until you are mere hunks of flesh, crippled wrecks of meat. And there will come a day when you have become so ruined that even I will be able to best you in combat, and you will submit to my peace.

Regular coffee consumption is associated with a decreased risk of several cancers (including breast, prostate, colorectal, and endometrial), cardiovascular disease, type 2 diabetes, Parkinson’s disease, dementia, and possibly depression and suicide. (Though high doses can produce nervousness and anxiety, and chances of committing suicide climb among those who drink eight or more cups a day.)

Yes, Dad— I liked that call we had yesterday. It carried me hundreds of miles away to a creek bed in Tennessee. To those days when we knew just what to do with the fragile things. Those days when your pick was steady.

Medical Benefits of Fasting Here are a few medical benefits from an article from John Hopkins Health Review Spring Summer 2016. Mark Mattson is a professor of neuroscience at the Johns Hopkins School of Medicine and also serves as chief of the Laboratory of Neurosciences at the National Institute on Aging. According to the research conducted by him and others, cutting your energy intake by fasting several days a week might help your brain ward off neurodegenerative diseases like Alzheimer’s and Parkinson’s while at the same time improving memory and mood. Mattson explains that every time you eat, glucose is stored in your liver as glycogen, which takes about 10 to 12 hours to be depleted. After the glycogen is used up, your body starts burning fats, which are converted to ketone bodies, acidic chemicals used by neurons as energy. Ketones promote positive changes in the structure of synapses important for learning, memory, and overall brain health. But if you eat three meals a day with snacks between, your body doesn’t have the chance to deplete the glycogen stores in your liver, and the ketones aren’t produced.

Another study, following 7,504 men over 30 years, found a 2.3-fold increase in Parkinson’s in men who consumed more than 16 ounces of milk a day, compared to those who consumed none. “Contamination of milk with neurotoxins may be of critical importance,” the scientists wrote.

so fast these days, it’s

Parkinson’s Law states that “work expands so as to fill the time available for its completion.” If you give yourself 2 hours to finish a task, you’ll take 2 hours to finish it. Give yourself 45 minutes and set a timer, and you’ll likely finish it in that amount of time.

Good News for Coffee Lovers For years many people who love a strong cup of freshly brewed coffee have felt guilty about what coffee might be doing to their health. A growing body of research studies, however, now suggests that drinking up to 3 to 5 cups of coffee a day plays a potential role in preventing a range of disorders, including type 2 diabetes, Parkinson’s disease, Alzheimer’s disease, cancer, and cardiovascular disease.

The Nursing Home There was an old man in a nursing home who had felt lonely since his wife had passed, and everyday he would sit at the same bench and stare at the trees in the yard. And elderly woman walked up to him one day and began to talk to him. She heard his story and was saddened by it, and asked if there was anything she could do to cheer him up. "Actually," the old man said, "you could hold my penis." At first the lady thought this was strange, but she figured since she wasn’t doing anything bad, just holding his penis. No harm done. Day after day, she’d meet the guy and hold his penis and they would talk for hours on end. She began to enjoy the time and thought nothing about the penis holding. One day she went to the spot to find that the man was not there. For the next week she didn’t see her friend at the bench and began to worry. She found a nurse and asked, "Did he pass away?" The woman held her breath, afraid of the answer. But the nurse responded, "Oh, no! He's been by the pool everyday for about a week now." The elderly lady didn't quite understand why, but she walked over to the pool to find him. When she got there, she saw him sitting next to the pool with another woman holding his penis! The woman was irate. "What's this?" she yelled at him. "Was my company not good enough for you? What does this woman have that I don't?" The man looked up with a smile and said, "Parkinson’s.

Luckily, human physiology offers one more pathway to power our brains. When food is no longer available, after about three days, the liver begins to use body fat to create those ketones. This is when beta-HBA serves as a highly efficient fuel source for the brain, allowing us to function cognitively for extended periods during food scarcity. Such an alternative fuel source helps reduce our dependence on gluconeogenesis and, therefore, preserves our muscle mass. But more than this, as Harvard Medical School professor George F. Cahill stated, “Recent studies have shown that beta-hydroxybutyrate, the principal ketone, is not just a fuel, but a superfuel, more efficiently producing ATP energy than glucose. It has also protected neuronal cells in tissue cultures against exposure to toxins associated with Alzheimer’s or Parkinson’s.”2

If you don’t drink coffee, you should think about two to four cups a day. It can make you more alert, happier, and more productive. It might even make you live longer. Coffee can also make you more likely to exercise, and it contains beneficial antioxidants and other substances associated with decreased risk of stroke (especially in women), Parkinson’s disease, and dementia. Coffee is also associated with decreased risk of abnormal heart rhythms, type 2 diabetes, and certain cancers.12

The drugs we use to treat Parkinson’s disease are indiscriminate, flooding the brain with dopamine without consideration to the delicate balance of the basal ganglia. A side effect of some of these dopaminergic drugs is a sort of hedonism, a compulsion to engage in addictive behaviors—sex, eating, gambling, shopping. The patients described in early reports on this phenomenon were nurses and pastors, computer programmers and car dealers. They were middle-aged and happily married before they began treating their Parkinson’s disease. Like the rats who learned to pull a lever for a rush of dopamine, they favored slot machines for the immediate payoff. After starting a dopaminergic medication, one patient reported that he felt an “incredible compulsion” to gamble, even when he “logically knew it was time to quit.” One sixty-eight-year-old man lost hundreds of thousands of dollars at casinos over six months, gambling for days at a time; his compulsion to gamble stopped entirely six months after stopping his medication. Another man gained fifty pounds and developed an addiction to pornography that stopped a month after he stopped his medications.