Neuroscience Brain Quotes

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Neuroscience research shows that the only way we can change the way we feel is by becoming aware of our inner experience and learning to befriend what is going inside ourselves.
Bessel van der Kolk (The Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma)
Any man could, if he were so inclined, be the sculptor of his own brain.
Santiago Ramón y Cajal (Advice for a Young Investigator (Mit Press))
Music, uniquely among the arts, is both completely abstract and profoundly emotional. It has no power to represent anything particular or external, but it has a unique power to express inner states or feelings. Music can pierce the heart directly; it needs no mediation.
Oliver Sacks (Musicophilia: Tales of Music and the Brain)
Oftentimes, those special brains, the ones that are capable of focusing more intently than others, do so at the expense of emotional maturity
Dan Brown (Inferno (Robert Langdon, #4))
Beneath the surface of the protective parts of trauma survivors there exists an undamaged essence, a Self that is confident, curious, and calm, a Self that has been sheltered from destruction by the various protectors that have emerged in their efforts to ensure survival. Once those protectors trust that it is safe to separate, the Self will spontaneously emerge, and the parts can be enlisted in the healing process
Bessel van der Kolk (The Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma)
How can a three-pound mass of jelly that you can hold in your palm imagine angels, contemplate the meaning of infinity, and even question its own place in the cosmos? Especially awe inspiring is the fact that any single brain, including yours, is made up of atoms that were forged in the hearts of countless, far-flung stars billions of years ago. These particles drifted for eons and light-years until gravity and change brought them together here, now. These atoms now form a conglomerate- your brain- that can not only ponder the very stars that gave it birth but can also think about its own ability to think and wonder about its own ability to wonder. With the arrival of humans, it has been said, the universe has suddenly become conscious of itself. This, truly, it the greatest mystery of all.
V.S. Ramachandran (The Tell-Tale Brain: A Neuroscientist's Quest for What Makes Us Human)
Nurturing your own development isn’t selfish. It’s actually a great gift to other people.
Rick Hanson (Buddha's Brain: The Practical Neuroscience of Happiness, Love, and Wisdom)
Psychologists usually try to help people use insight and understanding to manage their behavior. However, neuroscience research shows that very few psychological problems are the result of defects in understanding; most originate in pressures from deeper regions in the brain that drive our perception and attention. When the alarm bell of the emotional brain keeps signaling that you are in danger, no amount of insight will silence it.
Bessel van der Kolk (The Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma)
Vulnerability is the least celebrated emotion in our society
Mohadesa Najumi
The remedy is not to suppress negative experiences; when they happen, they happen. Rather, it is to foster positive experiences—and in particular, to take them in so they become a permanent part of you.
Rick Hanson (Buddha's Brain: The Practical Neuroscience of Happiness, Love, and Wisdom)
All joy in this world comes from wanting others to be happy, and all suffering in this world comes from wanting only oneself to be happy. —Shantideva
Rick Hanson (Buddha's Brain: The Practical Neuroscience of Happiness, Love, and Wisdom)
Imagine for a moment that we are nothing but the product of billions of years of molecules coming together and ratcheting up through natural selection, that we are composed only of highways of fluids and chemicals sliding along roadways within billions of dancing cells, that trillions of synaptic conversations hum in parallel, that this vast egglike fabric of micron-thin circuitry runs algorithms undreamt of in modern science, and that these neural programs give rise to our decision making, loves, desires, fears, and aspirations. To me, that understanding would be a numinous experience, better than anything ever proposed in anyone's holy text.
David Eagleman (Incognito: The Secret Lives of the Brain)
I don't trust anybody who isn't a little bit neurotic
Mohadesa Najumi
The neural processes underlying that which we call creativity have nothing to do with rationality. That is to say, if we look at how the brain generates creativity, we will see that it is not a rational process at all; creativity is not born out of reasoning.
Rodolfo R. Llinás (I of the Vortex: From Neurons to Self)
Only we humans worry about the future, regret the past, and blame ourselves for the present.
Rick Hanson (Buddha's Brain: The Practical Neuroscience of Happiness, Love, and Wisdom)
If our well-being depends upon the interaction between events in our brains and events in the world, and there are better and worse ways to secure it, then some cultures will tend to produce lives that are more worth living than others; some political persuasions will be more enlightened than others; and some world views will be mistaken in ways that cause needless human misery.
Sam Harris (The Moral Landscape: How Science Can Determine Human Values)
There is certainly a universal and unconscious propensity to impose a rhythm even when one hears a series of identical sounds at constant intervals... We tend to hear the sound of a digital clock, for example, as "tick-tock, tick-tock" - even though it is actually "tick tick, tick tick.
Oliver Sacks (Musicophilia: Tales of Music and the Brain)
Those who are nurtured best, survive best.
Louis Cozolino (The Neuroscience of Human Relationships: Attachment And the Developing Social Brain (Norton Series on Interpersonal Neurobiology))
The self is a repeatedly reconstructed biological state.
António R. Damásio (Descartes' Error: Emotion, Reason and the Human Brain)
Science results from a profoundly social process. The common portrayal—that science emerges from a solitary isolated genius, always laboring alone, not owing anything to anyone—is simply wrong.
Michael S. Gazzaniga (Tales from Both Sides of the Brain: A Life in Neuroscience)
There are, of course, inherent tendencies to repetition in music itself. Our poetry, our ballads, our songs are full of repetition; nursery rhymes and the little chants and songs we use to teach young children have choruses and refrains. We are attracted to repetition, even as adults; we want the stimulus and the reward again and again, and in music we get it. Perhaps, therefore, we should not be surprised, should not complain if the balance sometimes shifts too far and our musical sensitivity becomes a vulnerability.
Oliver Sacks (Musicophilia: Tales of Music and the Brain)
I take it as a compliment when somebody calls me crazy. I would be offended if I was one of the sheeple, one of the sleepwalkers in the matrix or part of the collective hallucination we call 'normal
Mohadesa Najumi
Life is a useless passion, an exciting journey of a mammal in survival mode. Each day is a miracle, a blessing unexplored and the more you immerse yourself in light, the less you will feel the darkness. There is more to life than nothingness. And cynicism. And nihilism. And selfishness. And glorious isolation. Be selfish with yourself, but live your life through your immortal acts, acts that engrain your legacy onto humanity. Transcend your fears and follow yourself into the void instead of letting yourself get eaten up by entropy and decay. Freedom is being yourself without permission. Be soft and leave a lasting impression on everybody you meet
Mohadesa Najumi
It’s easy to be kind when others treat you well. The challenge is to preserve your loving-kindness when they treat you badly—to preserve goodwill in the face of ill will.
Rick Hanson (Buddha's Brain: The Practical Neuroscience of Happiness, Love, and Wisdom)
I am a habitual rule-breaker
Mohadesa Najumi
Perception is never purely in the present - it has to draw on experience of the past;(...).We all have detailed memories of how things have previously looked and sounded, and these memories are recalled and admixed with every new perception.
Oliver Sacks (Musicophilia: Tales of Music and the Brain)
How about making a personal commitment never to go to sleep without having meditated that day, even if for just one minute?
Rick Hanson (Buddha's Brain: The Practical Neuroscience of Happiness, Love, and Wisdom)
I have been at war with parts of myself for so long
Mohadesa Najumi
Anatomists today would be hard put to identify the brain of a visual artist, a writer or a mathematician - but they would recognize the brain of a professional musician without moment's hesitation.
Oliver Sacks (Musicophilia: Tales of Music and the Brain)
You are not always right. It’s not always about being right. The best thing you can offer others is understanding. Being an active listener is about more than just listening, it is about reciprocating and being receptive to somebody else. Everybody has woes. Nobody is safe from pain. However, we all suffer in different ways. So learn to adapt to each person, know your audience and reserve yourself for people who have earned the depths of you
Mohadesa Najumi
The human brain is a cultural artifact. We don't load culture into a virgin brain like software loading into a computer; rather, culture helps to wire the brain. Brains then become carriers of culture, helping to create and perpetuate it.
Lisa Feldman Barrett (How Emotions Are Made: The Secret Life of the Brain)
Given her deafness, the auditory part of the brain, deprived of its usual input, had started to generate a spontaneous activity of its own, and this took the form of musical hallucinations, mostly musical memories from her earlier life. The brain needed to stay incessantly active, and if it was not getting its usual stimulation..., it would create its own stimulation in the form of hallucinations.
Oliver Sacks (Musicophilia: Tales of Music and the Brain)
[I]f you can be with the pleasant without chasing after it, with the unpleasant without resisting it, and with the neutral without ignoring it - [...] that is an incredible [...] freedom.
Rick Hanson (Buddha's Brain: The Practical Neuroscience of Happiness, Love, and Wisdom)
Maybe the human brain is an object beyond the reach of metaphor, for the simple reason that it is the only object capable of creating metaphors to describe itself. There really is nothing else like it. The human brain creates the human mind, and then the human mind tries to underhand the human brain, however long it takes and whatever the cost.
Luke Dittrich (Patient H.M.: A Story of Memory, Madness, and Family Secrets)
The problem is, when you depend on a substitute for love, you can never get enough.
Louis Cozolino (The Neuroscience of Human Relationships: Attachment And the Developing Social Brain (Norton Series on Interpersonal Neurobiology))
As modern-day neuroscience tells us, we are never in touch with the present, because neural information-processing itself takes time. Signals take time to travel from your sensory organs along the multiple neuronal pathways in your body to your brain, and they take time to be processed and transformed into objects, scenes, and complex situations. So, strictly speaking, what you are experiencing as the present moment is actually the past.
Thomas Metzinger (The Ego Tunnel: The Science of the Mind and the Myth of the Self)
Even though its common knowledge these days, it never ceases to amaze me that all the richness of our mental life - all our feelings, our emotions, our thoughts, our ambitions, our love life, our religious sentiments and even what each of us regards us his own intimate private self - is simply the activity of these little specks of jelly in your head, in your brain. There is nothing else.
V.S. Ramachandran (A Brief Tour of Human Consciousness: From Impostor Poodles to Purple Numbers)
One of the key practical lessons of modern neuroscience is that the power to direct our attention has within it the power to shape our brain’s firing patterns, as well as the power to shape the architecture of the brain itself.
Daniel J. Siegel (Mindsight: The New Science of Personal Transformation)
Every time you take in the good, you build a little bit of neural structure. Doing this a few times a day—for months and even years—will gradually change your brain, and how you feel and act, in far-reaching ways.
Rick Hanson (Buddha's Brain: The Practical Neuroscience of Happiness, Love, and Wisdom)
However, narrating what you remember, telling it to someone, does something else. The more a person recalls a memory, the more they change it. Each time they put it into language, it shifts. The more you describe a memory, the more likely it is that you are making a story that fits your life, resolves the past, creates a fiction you can live with. It’s what writers do. Once you open your mouth, you are moving away from the truth of things. According to neuroscience. The safest memories are locked in the brains of people who can’t remember. Their memories remain the closest replica of actual events. Underwater. Forever.
Lidia Yuknavitch (The Chronology of Water)
...there will never be enough drug, because the brain's capacity to learn and adapt is basically infinite.
Judith Grisel (Never Enough: The Neuroscience and Experience of Addiction)
Fairytales are healthy for the children. As they grow up, the magical thinking wears off, but the fairytale-induced creative brain circuits stay forever.
Abhijit Naskar
Your fear of becoming a cliche is what turns you into one. If you remove the fear, we are all really walking contradictions, hypocrites and paradoxical cliches
Mohadesa Najumi
If we could read the secret history of our enemies, we should find in each [person’s] life sorrow and suffering enough to disarm any hostility. —Henry Wadsworth Longfellow
Rick Hanson (Buddha's Brain: The Practical Neuroscience of Happiness, Love, and Wisdom)
Stereotypes could be straitjackening our flexible, plastic brains. So, yes, challenging them does matter.
Gina Rippon (The Gendered Brain: The New Neuroscience That Shatters the Myth of the Female Brain)
What have we learned so far about the human brain? It messes with memories, it jumps at shadows, it's terrified of harmless things, it screws with our diet, our sleeping, our movement, it convinces us we're brilliant when we're not, it makes up half the stuff we perceive, it gets us to do irrational things when emotional, it causes us to make friends incredibly quickly and turn on them in an instant. A worrying list. What's even more worrying, it does all of this when it's working properly.
Dean Burnett (The Idiot Brain: A Neuroscientist Explains What Your Head Is Really Up To)
Resentment is when I take poison and wait for you to die.
Rick Hanson (Buddha's Brain: The Practical Neuroscience of Happiness, Love, and Wisdom)
Taking in the good is not about putting a happy shiny face on everything, nor is it about turning away from the hard things in life. It's about nourishing well-being, contentment, and peace inside that are refuges you can always come from and return to.
Rick Hanson (Buddha's Brain: The Practical Neuroscience of Happiness, Love, and Wisdom)
First darts are unpleasant to be sure. But then we add our reactions to them. These reactions are “second darts”—the ones we throw ourselves. Most of our suffering comes from second darts.
Rick Hanson (Buddha's Brain: The Practical Neuroscience of Happiness, Love, and Wisdom)
I do not see emotions and feelings as the intangible and vaporous qualities that many presume them to be. Their subject matter is concrete, and they can be related to specific systems in body and brain, no less so than vision or speech.
António R. Damásio (Descartes' Error: Emotion, Reason and the Human Brain)
The purpose of all of this (left hemisphere's way of choosing denial or repression over considering an anomaly) is to impose stability on behavior and to prevent vacillation because indecisiveness doesn't serve any purpose. Any decision, so long as it is probably correct, is better than no decision at all. A perpetually fickle general will never win a war.
V.S. Ramachandran (Phantoms in the Brain: Probing the Mysteries of the Human Mind)
Oxytocin, a hormone and neuropeptide ... plays a major role in attachment processes and serves several purposes: It causes women to go into labor, strengthens attachment, and ... [increases] trust and cooperation. We get a boost of oxytocin in our brain during orgasm and even when we cuddle -- which is why it's been tagged the "cuddle hormone." How is oxytocin related to conflict reduction? Sometimes we spend less quality time with our partner -- especially when other demands on us are pressing. However, neuroscience findings suggest that we should change our priorities. By forgoing closeness with our partners, we are also missing our oxytocin boost -- making us less agreeable to the world around us and more vulnerable to conflict.
Amir Levine (Attached: The New Science of Adult Attachment and How It Can Help You Find—and Keep—Love)
Neuroscience tells us that it is highly improbable that we have souls, as everything we think and feel is no more or no less than the electrochemical chatter of our nerve cells. Our sense of self, our feelings and our thoughts, our love for others, our hopes and ambitions, our hates and fears all die when our brains die. Many people deeply resent this view of things, which not only deprives us of life after death but also seems to downgrade thought to mere electrochemistry and reduces us to mere automata, to machines. Such people are profoundly mistaken, since what it really does is upgrade matter into something infinitely mysterious that we do not understand. There are one hundred billion nerve cells in our brains. Does each one have a fragment of consciousness within it? How many nerve cells do we require to be conscious or to feel pain? Or does consciousness and thought reside in the electrochemical impulses that join these billions of cells together? Is a snail aware? Does it feel pain when you crush it underfoot? Nobody knows.
Henry Marsh (Do No Harm: Stories of Life, Death, and Brain Surgery)
I learned an important lesson: Never take the obvious for granted. Once upon a time, it was so obvious that a four-pound rock would plummet earthward twice as fast as a two-pound rock that no one ever bothered to test it. That is, until Galileo Galilei came along and took ten minutes to perform an elegantly simple experiment that yielded a counterintuitive result and changed the course of history.
V.S. Ramachandran (The Tell-Tale Brain: A Neuroscientist's Quest for What Makes Us Human)
Just a dozen of high quality qudits will be sufficient to simulate the state of 100 billion neurons of human brain for quantum machine learning.
Amit Ray (Quantum Computing Algorithms for Artificial Intelligence)
And now all those brain cells are dead – and my mother – who in a sense was the complex electrochemical interaction of all these millions of neurons – is no more. In neuroscience it is called ‘the binding problem’ – the extraordinary fact, which nobody can even begin to explain, that mere brute matter can give rise to consciousness and sensation. I had such a strong sensation, as she lay dying, that some deeper, ‘real’ person was still there behind the death mask.
Henry Marsh (Do No Harm: Stories of Life, Death and Brain Surgery)
...what draws us into a story and keeps us there is the firing of our dopamine neurons, signaling that intriguing information is on the way.
Lisa Cron (Wired for Story: The Writer's Guide to Using Brain Science to Hook Readers from the Very First Sentence)
Because vision appears so effortless, we are like fish challenged to understand water.
David Eagleman (Incognito: The Secret Lives of the Brain)
the study of psychophysics proves that it is impossible to bore a German.” Thankfully,
Michael S. Gazzaniga (Tales from Both Sides of the Brain: A Life in Neuroscience)
The cause-effect sequences in our brains are just as determining, just as inescapable, as anywhere else in Nature.
Corliss Lamont
Our inability to understand our own minds is the price we pay for the ability to question it in the first place.
Helen Thomson (Unthinkable: What the World's Most Extraordinary Brains Can Teach Us About Our Own)
Whatever positive facts you find, bring a mindful awareness to them—open up to them and let them affect you. It’s like sitting down to a banquet: don’t just look at it—dig in!
Rick Hanson (Buddha's Brain: The Practical Neuroscience of Happiness, Love, and Wisdom)
I believe that things just happen in life, and pretty much after the fact, we make up a story to make it all seem rational. We all like simple stories that suggest a causal chain to life’s events. Yet randomness is ever present.
Michael S. Gazzaniga (Tales from Both Sides of the Brain: A Life in Neuroscience)
Recent brain scans have shed light on how the brain simulates the future. These simulation are done mainly in the dorsolateral prefrontal cortex, the CEO of the brain, using memories of the past. On one hand, simulations of the future may produce outcomes that are desirable and pleasurable, in which case the pleasure centers of the brain light up (in the nucleus accumbens and the hypothalamus). On the other hand, these outcomes may also have a downside to them, so the orbitofrontal cortex kicks in to warn us of possible dancers. There is a struggle, then, between different parts of the brain concerning the future, which may have desirable and undesirable outcomes. Ultimately it is the dorsolateral prefrontal cortex that mediates between these and makes the final decisions. (Some neurologists have pointed out that this struggle resembles, in a crude way, the dynamics between Freud's ego, id, and superego.)
Michio Kaku (The Future of the Mind: The Scientific Quest to Understand, Enhance, and Empower the Mind)
What makes human life meaningful? I still felt literature provided the best account of the life of the mind, while neuroscience laid down the most elegant rules of the brain.
Paul Kalanithi (When Breath Becomes Air)
Call it order, call it chaos, it’s all in the brain.
Abhijit Naskar (Mission Reality)
If you change the way your brain processes an event, you change the duration of the ‘now.’ You actually change the point at which the present becomes the past.
Blake Crouch (Recursion)
It's impossible to change the past or the present: you can only accept all that as it is.
Rick Hanson (Buddha's Brain: The Practical Neuroscience of Happiness, Love, and Wisdom)
When a monkey loses a banana to a rival, he feels bad, but he doesn't expand the problem by thinking about it over and over. He looks for another banana. He ends up feeling rewarded rather than harmed. Humans use their extra neurons to construct theories about bananas and end up constructing pain.
Loretta Graziano Breuning (Habits of a Happy Brain: Retrain Your Brain to Boost Your Serotonin, Dopamine, Oxytocin, & Endorphin Levels)
Barry L. Jacobs and colleagues from the neuroscience program at Princeton University showed that when mice ran every day on an exercise wheel, they developed more brain cells and they learned faster than sedentary controls. I believe in mice.
Bernd Heinrich (Why We Run: A Natural History)
A person cannot direct his emotional life in the way he bids his motor system to reach for a cup. He cannot will himself to want the right thing or to love the right person or to be happy after a disappointment, or even to be happy in happy times. People lack this capacity not through a deficiency of discipline but because the jurisdiction of will is limited to the latest brain and to those functions within its purview. Emotional life can be influenced, but it cannot be commanded.
Thomas Lewis (A General Theory of Love)
When you're anxious, don't immediately trust your automatic thoughts because oftentimes these thoughts are irrational. Thoughts are not facts. They're just thoughts and sometimes don't need to be given so much importance.
John Tsilimparis (Retrain Your Anxious Brain: Practical and Effective Tools to Conquer Anxiety)
It is difficult to overstate the importance of understanding mirror neurons and their function. They may well be central to social learning, imitation, and the cultural transmission of skills and attitudes—perhaps even of the pressed-together sound clusters we call words. By hyperdeveloping the mirror-neuron system, evolution in effect turned culture into the new genome. Armed with culture, humans could adapt to hostile new environments and figure out how to exploit formerly inaccessible or poisonous food sources in just one or two generations—instead of the hundreds or thousands of generations such adaptations would have taken to accomplish through genetic evolution. Thus culture became a significant new source of evolutionary pressure, which helped select brains that had even better mirror-neuron systems and the imitative learning associated with them. The result was one of the many self-amplifying snowball effects that culminated in Homo sapiens, the ape that looked into its own mind and saw the whole cosmos reflected inside.
V.S. Ramachandran (The Tell-Tale Brain: A Neuroscientist's Quest for What Makes Us Human)
Fighting the Blues with Greens Here’s a statistic you probably haven’t heard: Higher consumption of vegetables may cut the odds of developing depression by as much as 62 percent.26 A review in the journal Nutritional Neuroscience concluded that, in general, eating lots of fruits and veggies may present “a non-invasive, natural, and inexpensive therapeutic means to support a healthy brain.
Michael Greger (How Not to Die: Discover the Foods Scientifically Proven to Prevent and Reverse Disease)
It’s a remarkable fact that the people who have gone the very deepest into the mind—the sages and saints of every religious tradition—all say essentially the same thing: your fundamental nature is pure, conscious, peaceful, radiant, loving, and wise, and it is joined in mysterious ways with the ultimate underpinnings of reality, by whatever name we give That.
Rick Hanson (Buddha's Brain: The Practical Neuroscience of Happiness, Love, and Wisdom)
Recent experiments in neuroscience support the view that it is our physical brain, following the known laws of science, that determines our actions, and not some agency that exists outside those laws. For example, a study of patients undergoing awake brain surgery found that by electrically stimulating the appropriate regions of the brain, one could create in the patient the desire to move the hand, arm or foot, or to move the lips and talk. It is hard to imagine how free will can operate if our behaviour is determined by physical law, so it seems that we are no more than biological machines and that free will is just an illusion.
Stephen Hawking (The Grand Design)
Brené Brown writes: In a 2011 study funded by the National Institute on Drug Abuse, researchers found that, as far as the brain is concerned, physical pain and intense experiences of social rejection hurt in the same way…Neuroscience advances confirm what we’ve known all along: emotions can hurt and cause pain. And just as we often struggle to define physical pain, describing emotional pain is difficult. Shame is particularly hard because it hates having words wrapped around it. It hates being spoken.
Amanda Palmer (The Art of Asking; or, How I Learned to Stop Worrying and Let People Help)
The act of reading together secures people to one another, creating order and connection, as if we were quilt squares tacked together with threads made of stories. That's not just another metaphor, as a team of neuroscientists at Princeton has discovered. Even as reader and listener are enjoying their bouquet of neurochemicals ... their brain activity is synchronizing, creating literal order and connection in a process known as neural coupling.
Meghan Cox Gurdon (The Enchanted Hour: The Miraculous Power of Reading Aloud in the Age of Distraction)
From a neuroscience perspective we are all divided and discontinuous. The mental processes underlying our sense of self-- feelings, thoughts, memories-- are scattered through different zones of the brain. There is no special point of convergence. No cockpit of the soul. No soul-pilot. They come together in a work of fiction. A human being is a story-telling machine. The self is a story.
Paul Broks (Into the Silent Land: Travels in Neuropsychology)
Neuro-nonsense occurs when people take on board the supposed discoveries of neuroscience – all these brain images that tell us, for instance, that we’ve discovered now exactly what love is, it’s this little bit in the hippocampus, so we have no need to question what the meaning of these things is. But these images have no meaning, any more than a chemical reaction in a test-tube has a meaning. All kinds of nonsense comes into being as a result of this, the nonsense being essentially what happens when our own human nature is confiscated from us by science or pseudosciences which claim to explain us without really going into the question of what we are.
Roger Scruton (The Soul of the World)
What we found was that rather than being haphazardly arranged or independent pathways, we find that all of the pathways of the brain taken together fit together in a single exceedingly simple structure. They basically look like a cube. They basically run in three perpendicular directions, and in each one of those three directions the pathways are highly parallel to each other and arranged in arrays. So, instead of independent spaghettis, we see that the connectivity of the brain is, in a sense, a single coherent structure.
Ray Kurzweil (How to Create a Mind: The Secret of Human Thought Revealed)
one of the surprises that has shaken the very foundations of neuroscience is the discovery that the brain is actually “plastic,” or moldable. This means that the brain physically changes throughout the course of our lives, not just in childhood, as we had previously assumed. What molds our brain? Experience. Even into old age, our experiences actually change the physical structure of the brain.
Daniel J. Siegel (The Whole-Brain Child: 12 Revolutionary Strategies to Nurture Your Child's Developing Mind)
Anxiety is a complex emotional response that’s similar to fear. Both arise from similar brain processes and cause similar physiological and behavioral reactions; both originate in portions of the brain designed to help all animals deal with danger. Fear and anxiety differ, however, in that fear is typically associated with a clear, present, and identifiable threat, whereas anxiety occurs in the absence of immediate peril.
Catherine M. Pittman (Rewire Your Anxious Brain: How to Use the Neuroscience of Fear to End Anxiety, Panic, and Worry)
The very definition of an addictive drug is one that stimulates the mesolimbic pathway, but there are three general axioms in psychopharmacology that also apply to all drugs: 1. All drugs act by changing the rate of what is already going on. 2. All drugs have side effects. 3. The brain adapts to all drugs that affect it by counteracting the drug’s effects.
Judith Grisel (Never Enough: The Neuroscience and Experience of Addiction)
The part of my brain that was responsible for creating the world I lived and moved in and for taking the raw data that came in through my senses and fashioning it into a meaningful universe: that part of my brain was down, and out. And yet despite all of this, I had been alive, and aware, truly aware, in a universe characterized above all by love, consciousness, and reality. There was, for me, simply no arguing this fact. I knew it so completely that I ached.
Eben Alexander
Speechlessness, however, affirmed in the diagnosis, is carefully based on the facts of the examination, as we see by rendering the statements concerned, just as they stand in examination and diagnosis: "If thou examinest a man having a wound in the temple, ...; if thou ask of him concerning his malady and he speak not to thee; ...; thou shouldst say concerning him, 'One having a wound in his temple, ... (and) he is speechless'.
James Henry Breasted (The Edwin Smith Surgical Papyrus, Vol 1: Hieroglyphic Transliteration, Translation and Commentary)
Genetics, accidents of birth or events in early childhood have left criminals' brains and bodies with measurable flaws predisposing them to committing assault, murder and other antisocial acts. .... Many offenders also have impairments in their autonomic nervous system, the system responsible for the edgy, nervous feeling that can come with emotional arousal. This leads to a fearless, risk-taking personality, perhaps to compensate for chronic under-arousal. Many convicted criminals, like the Unabomber, have slow heartbeats. It also gives them lower heart rates, which explains why heart rate is such a good predictor of criminal tendencies. The Unabomber, Ted Kaczynski, for example, had a resting heart rate of just 54 beats per minute, which put him in the bottom 3 per cent of the population.
Adrian Raine
Our metaphors for the operation of the brain are frequently drawn from the production line. We think of the brain as a glorified sausage machine, taking in information from the senses, processing it and regurgitating it in a different form, as thoughts or actions. The digital computer reinforces this idea because it is quite explicitly a machine that does to information what a sausage machine does to pork. Indeed, the brain was the original inspiration and metaphor for the development of the digital computer, and early computers were often described as 'giant brains'. Unfortunately, neuroscientists have sometimes turned this analogy on its head, and based their models of brain function on the workings of the digital computer (for example by assuming that memory is separate and distinct from processing, as it is in a computer). This makes the whole metaphor dangerously self-reinforcing.
Steve Grand (Creation: Life and How to Make It)
The lessons of relationship that our primordial ancestors learned are deeply encoded in the genetics of our neurobiological circuits of love. They are present from the moment we are born and activated at puberty by the cocktail of neurochemicals. It’s an elegant synchronized system. At first our brain weighs a potential partner, and if the person fits our ancestral wish list, we get a spike in the release of sex chemicals that makes us dizzy with a rush of unavoidable infatuation. It’s the first step down the primeval path of pair-bonding.
Abhijit Naskar (What is Mind?)
The disappearance of medial prefrontal activation could explain why so many traumatized people lose their sense of purpose and direction. I used to be surprised by how often my patients asked me for advice about the most ordinary things, and then by how rarely they followed it. Now I understood that their relationship with their own inner reality was impaired. How could they make decisions, or put any plan into action, if they couldn't define what they wanted or, to be more precise, what the sensations in their bodies, the basis of all emotions, were trying to tell them?
Bessel van der Kolk (The Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma)
The word “coherence” literally means holding or sticking together, but it is usually used to refer to a system, an idea, or a worldview whose parts fit together in a consistent and efficient way. Coherent things work well: A coherent worldview can explain almost anything, while an incoherent worldview is hobbled by internal contradictions. … Whenever a system can be analyzed at multiple levels, a special kind of coherence occurs when the levels mesh and mutually interlock. We saw this cross-level coherence in the analysis of personality: If your lower-level traits match up with your coping mechanisms, which in turn are consistent with your life story, your personality is well integrated and you can get on with the business of living. When these levels do not cohere, you are likely to be torn by internal contradictions and neurotic conflicts. You might need adversity to knock yourself into alignment. And if you do achieve coherence, the moment when things come together may be one of the most profound of your life. … Finding coherence across levels feels like enlightenment, and it is crucial for answering the question of purpose within life. People are multilevel systems in another way: We are physical objects (bodies and brains) from which minds somehow emerge; and from our minds, somehow societies and cultures form. To understand ourselves fully we must study all three levels—physical, psychological, and sociocultural. There has long been a division of academic labor: Biologists studied the brain as a physical object, psychologists studied the mind, and sociologists and anthropologists studied the socially constructed environments within which minds develop and function. But a division of labor is productive only when the tasks are coherent—when all lines of work eventually combine to make something greater than the sum of its parts. For much of the twentieth century that didn’t happen — each field ignored the others and focused on its own questions. But nowadays cross-disciplinary work is flourishing, spreading out from the middle level (psychology) along bridges (or perhaps ladders) down to the physical level (for example, the field of cognitive neuroscience) and up to the sociocultural level (for example, cultural psychology). The sciences are linking up, generating cross-level coherence, and, like magic, big new ideas are beginning to emerge. Here is one of the most profound ideas to come from the ongoing synthesis: People gain a sense of meaning when their lives cohere across the three levels of their existence.
Jonathan Haidt (The Happiness Hypothesis: Finding Modern Truth in Ancient Wisdom)
You might think my chosen career would lend me insight…. But while I can tell you about the brain as a physical object…, beyond that I am a glorified techie. I know the nuts and bolts and can diagnose flaws within the mainframe. While I can identify and sometimes fix structural maladies within that organ, I do not remotely understand it. That is an impossible task, like trying to guess the path rainwater will take down a windowpane. There is simply no way to know with any accuracy what is happening inside someone else’s head. I only faintly comprehend what is going on inside my own.
Craig Davidson (The Saturday Night Ghost Club)
Each electrical pulse—and resulting squirt of neurotransmitter—is not an order commanding the next neuron’s actions; it is more like a vote on what the next neuron should do. The whole pattern of activity is like a presidential election. Everyone votes on who the president should be, and depending on those votes, the country veers off in one direction or another. If you can change the number of votes in a few key swing states by only a few percentage points, you can dramatically change the course of the country. The same is true of the brain. By changing the firing rate of neurons in a few key regions, you can influence the pattern of activity in the entire brain.
Alex Korb (The Upward Spiral: Using Neuroscience to Reverse the Course of Depression, One Small Change at a Time)
Stage one—you’re caught in a second-dart reaction and don’t even realize it: your partner forgets to bring milk home and you complain angrily without seeing that your reaction is over the top. Stage two—you realize you’ve been hijacked by greed or hatred (in the broadest sense), but cannot help yourself: internally you’re squirming, but you can’t stop grumbling bitterly about the milk. Stage three—some aspect of the reaction arises, but you don’t act it out: you feel irritated but remind yourself that your partner does a lot for you already and getting cranky will just make things worse. Stage four—the reaction doesn’t even come up, and sometimes you forget you ever had the issue: you understand that there’s no milk, and you calmly figure out what to do now with your partner. In education, these are known succinctly as unconscious incompetence, conscious incompetence, conscious competence, and unconscious competence. They’re useful
Rick Hanson (Buddha's Brain: The Practical Neuroscience of Happiness, Love, and Wisdom)
Were we dealing with a spectrum-based system that described male and female sexuality with equal accuracy, data taken from gay males would look similar to data taken from straight females—and yet this is not what we see in practice. Instead, the data associated with gay male sexuality presents a mirror image of data associated with straight males: Most gay men are as likely to find the female form aversive as straight men are likely to find the male form aversive. In gay females we observe a similar phenomenon, in which they mirror straight females instead of appearing in the same position on the spectrum as straight men—in other words, gay women are just as unlikely to find the male form aversive as straight females are to find the female form aversive. Some of the research highlighting these trends has been conducted with technology like laser doppler imaging (LDI), which measures genital blood flow when individuals are presented with pornographic images. The findings can, therefore, not be written off as a product of men lying to hide middling positions on the Kinsey scale due to a higher social stigma against what is thought of in the vernacular as male bisexuality/pansexuality. We should, however, note that laser Doppler imaging systems are hardly perfect, especially when measuring arousal in females. It is difficult to attribute these patterns to socialization, as they are observed across cultures and even within the earliest of gay communities that emerged in America, which had to overcome a huge amount of systemic oppression to exist. It’s a little crazy to argue that the socially oppressed sexuality of the early American gay community was largely a product of socialization given how much they had overcome just to come out. If, however, one works off the assumptions of our model, this pattern makes perfect sense. There must be a stage in male brain development that determines which set of gendered stimuli is dominant, then applies a negative modifier to stimuli associated with other genders. This stage does not apparently take place during female sexual development. 
Simone Collins (The Pragmatist’s Guide to Sexuality: What Turns People On, Why, and What That Tells Us About Our Species (The Pragmatist's Guide))
Meditation has also been proven scientifically to untangle and rewire the neurological pathways in the brain that make up the conditioned personality. Buddhist monks, for example, have had their brains scanned by scientists as they sat still in deep altered states of consciousness invoked by transcendental meditation and the scientists were amazed at what they beheld. The frontal lobes of the monks lit up as bright as the sun! They were in states of peace and happiness the scientists had never seen before. Meditation invokes that which is known in neuroscience as neuroplasticity; which is the loosening of the old nerve cells or hardwiring in the brain, to make space for the new to emerge. Meditation, in this sense, is a fire that burns away the old or conditioned self, in the Bhagavad Gita, this is known as the Yajna; “All karma or effects of actions are completely burned away from the liberated being who, free from attachment, with his physical mind enveloped in wisdom (the higher self), performs the true spiritual fire rite.
Craig Krishna (The Labyrinth: Rewiring the Nodes in the Maze of your Mind)
It might weigh little over a kilogram but, taken on its own scale, the brain is unimaginably vast. One cubic millimetre contains between twenty and twenty-five thousand neurons. It has eighty-six billion of these cells, and each one is complex as a city and is in contact with ten thousand other neurons just like it. Within just one cubic centimetre of brain tissue, there is the same number of connections as there are stars in the Milky Way. Your brain contains a hundred trillion of them. Information in the form of electricity and chemicals flows around these paths in great forking trails and in circuits and feedback loops and fantastical storms of activity tat bloom to life speeds of up to a hundred and twenty metres per second. According to the neuroscientist V. S. Ramachandran, 'The number of permutations and combinations of activity that are theoretically possible exceeds the number of elementary particles in the universe.' And yet, he continues, 'We know so little about it that even a child's questions should be seriously entertained.
Will Storr (The Unpersuadables: Adventures wiith the Enemies of Science)
Since then neuroscience research has shown that we possess two distinct forms of self-awareness: one that keeps track of the self across time and one that registers the self in the present moment. The first, our autobiographical self, creates connections among experiences and assembles them into a coherent story. This system is rooted in language. Our narratives change with the telling, as our perspective changes and as we incorporate new input. The other system, moment-to-moment self-awareness, is based primarily in physical sensations, but if we feel safe and are not rushed, we can find words to communicate that experience as well. These two ways of knowing are localized in different parts of the brain that are largely disconnected from each other.10 Only the system devoted to self-awareness, which is based in the medial prefrontal cortex, can change the emotional brain. In the groups I used to lead for veterans, I could sometimes see these two systems working side by side. The soldiers told horrible tales of death and destruction, but I noticed that their bodies often simultaneously radiated a sense of pride and belonging.
Bessel van der Kolk (The Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma)
... [O]ne of the most influential approaches to thinking about memory in recent years, known as connectionism, has abandoned the idea that a memory is an activated picture of a past event. Connectionist or neural network models are based on the principle that the brain stores engrams by increasing the strength of connections between different neurons that participate in encoding an experience. When we encode an experience, connections between active neurons become stronger, and this specific pattern of brain activity constitutes the engram. Later, as we try to remember the experience, a retrieval cue will induce another pattern of activity in the brain. If this pattern is similar enough to a previously encoded pattern, remembering will occur. The "memory" in a neural network model is not simply an activated engram, however. It is a unique pattern that emerges from the pooled contributions of the cue and the engram. A neural network combines information in the present environment with patterns that have been stored in the past, and the resulting mixture of the two is what the network remembers... When we remember, we complete a pattern with the best match available in memory; we do not shine a spotlight on a stored picture.
Daniel L. Schacter (Searching for Memory: The Brain, the Mind, and the Past)
It is important to note that the design of an entire brain region is simpler than the design of a single neuron. As discussed earlier, models often get simpler at a higher level—consider an analogy with a computer. We do need to understand the detailed physics ofsemiconductors to model a transistor, and the equations underlying a single real transistor are complex. A digital circuit that multiples two numbers requires hundreds of them. Yet we can model this multiplication circuit very simply with one or two formulas. An entire computer with billions of transistors can be modeled through its instruction set and register description, which can be described on a handful of written pages of text and formulas. The software programs for an operating system, language compilers, and assemblers are reasonably complex, but modeling a particular program—for example, a speech recognition programbased on hierarchical hidden Markov modeling—may likewise be described in only a few pages of equations. Nowhere in such a description would be found the details ofsemiconductor physics or even of computer architecture. A similar observation holds true for the brain. A particular neocortical pattern recognizer that detects a particular invariant visualfeature (such as a face) or that performs a bandpass filtering (restricting input to a specific frequency range) on sound or that evaluates the temporal proximity of two events can be described with far fewer specific details than the actual physics and chemicalrelations controlling the neurotransmitters, ion channels, and other synaptic and dendritic variables involved in the neural processes. Although all of this complexity needs to be carefully considered before advancing to the next higher conceptual level, much of it can be simplified as the operating principles of the brain are revealed.
Ray Kurzweil (How to Create a Mind: The Secret of Human Thought Revealed)