Medical Biochemistry Quotes

Next is diet or nutrition—or as I prefer to call it, nutritional biochemistry. The third domain is sleep, which has gone underappreciated by Medicine 2.0 until relatively recently. The fourth domain encompasses a set of tools and techniques to manage and improve emotional health. Our fifth and final domain consists of the various drugs, supplements, and hormones that doctors learn about in medical school and beyond. I lump these into one bucket called exogenous molecules, meaning molecules we ingest that come from outside the body.

The detox phenomenon is interesting because it represents one of the most grandiose innovations of marketers, lifestyle gurus, and alternative therapists: the invention of a whole new physiological process. In terms of basic human biochemistry, detox is a meaningless concept. It doesn’t cleave nature at the joints. There is nothing on the “detox system” in a medical textbook. That burgers and beer can have negative effects on your body is certainly true, for a number of reasons; but the notion that they leave a specific residue, which can be extruded by a specific process, a physiological system called detox, is a marketing invention.

And it wasn’t just Marla. I witnessed similar transformations in dozens of patients. I finally realized that the medical establishment’s nearly exclusive focus on the biochemistry of the patient’s body, often to the exclusion of the health of the patient’s mind, was doing our patients a grave disservice.

depression can occur because of biological factors such as genetic predispositions, hormonal changes (including menopause, childbirth or thyroid problems) and differences in biochemistry (an imbalance of naturally occurring substances called neurotransmitters in the brain and spinal cord). In other cases, depression is caused by psychological factors, severe life stressors, substance abuse and certain medical conditions that affect the way your brain regulates your moods.

The night before a biochemistry class, I read the last year's lecture notes. I look at the pictures in the book. Now, I've got the general concept. Sure...There's a couple of details to fill in and a a few things to memorize. But that's no big deal. I've got the big picture, and that's all I need. Bring it on professor, I'm ready. That's right. The next day, I'm a goalie sitting in the front row. "Nothin gets past me." My ability to comprehend a biochemistry lecture just went from 30% to 95%. I went on to score 780 out of a possible 800 on the medical school boards exam in biochemistry. Given that the 99th percentile began around 690, this was one of the highest scores in the USA, perhaps the highest.

REPROGRAMMING MY BIOCHEMISTRY A common attitude is that taking substances other than food, such as supplements and medications, should be a last resort, something one takes only to address overt problems. Terry and I believe strongly that this is a bad strategy, particularly as one approaches middle age and beyond. Our philosophy is to embrace the unique opportunity we have at this time and place to expand our longevity and human potential. In keeping with this health philosophy, I am very active in reprogramming my biochemistry. Overall, I am quite satisfied with the dozens of blood levels I routinely test. My biochemical profile has steadily improved during the years that I have done this. For boosting antioxidant levels and for general health, I take a comprehensive vitamin-and-mineral combination, alpha lipoic acid, coenzyme Q10, grapeseed extract, resveratrol, bilberry extract, lycopene, silymarin (milk thistle), conjugated linoleic acid, lecithin, evening primrose oil (omega-6 essential fatty acids), n-acetyl-cysteine, ginger, garlic, l-carnitine, pyridoxal-5-phosphate, and echinacea. I also take Chinese herbs prescribed by Dr. Glenn Rothfeld. For reducing insulin resistance and overcoming my type 2 diabetes, I take chromium, metformin (a powerful anti-aging medication that decreases insulin resistance and which we recommend everyone over 50 consider taking), and gymnema sylvestra. To improve LDL and HDL cholesterol levels, I take policosanol, gugulipid, plant sterols, niacin, oat bran, grapefruit powder, psyllium, lecithin, and Lipitor. To improve blood vessel health, I take arginine, trimethylglycine, and choline. To decrease blood viscosity, I take a daily baby aspirin and lumbrokinase, a natural anti-fibrinolytic agent. Although my CRP (the screening test for inflammation in the body) is very low, I reduce inflammation by taking EPA/DHA (omega-3 essential fatty acids) and curcumin. I have dramatically reduced my homocysteine level by taking folic acid, B6, and trimethylglycine (TMG), and intrinsic factor to improve methylation. I have a B12 shot once a week and take a daily B12 sublingual. Several of my intravenous therapies improve my body’s detoxification: weekly EDTA (for chelating heavy metals, a major source of aging) and monthly DMPS (to chelate mercury). I also take n-acetyl-l-carnitine orally. I take weekly intravenous vitamins and alpha lipoic acid to boost antioxidants. I do a weekly glutathione IV to boost liver health. Perhaps the most important intravenous therapy I do is a weekly phosphatidylcholine (PtC) IV, which rejuvenates all of the body’s tissues by restoring youthful cell membranes. I also take PtC orally each day, and I supplement my hormone levels with DHEA and testosterone. I take I-3-C (indole-3-carbinol), chrysin, nettle, ginger, and herbs to reduce conversion of testosterone into estrogen. I take a saw palmetto complex for prostate health. For stress management, I take l-theonine (the calming substance in green tea), beta sitosterol, phosphatidylserine, and green tea supplements, in addition to drinking 8 to 10 cups of green tea itself. At bedtime, to aid with sleep, I take GABA (a gentle, calming neuro-transmitter) and sublingual melatonin. For brain health, I take acetyl-l-carnitine, vinpocetine, phosphatidylserine, ginkgo biloba, glycerylphosphorylcholine, nextrutine, and quercetin. For eye health, I take lutein and bilberry extract. For skin health, I use an antioxidant skin cream on my face, neck, and hands each day. For digestive health, I take betaine HCL, pepsin, gentian root, peppermint, acidophilus bifodobacter, fructooligosaccharides, fish proteins, l-glutamine, and n-acetyl-d-glucosamine. To inhibit the creation of advanced glycosylated end products (AGEs), a key aging process, I take n-acetyl-carnitine, carnosine, alpha lipoic acid, and quercetin. MAINTAINING A POSITIVE “HEALTH SLOPE” Most important,

I didn’t invent my regimen from whole cloth. It’s built on a foundation of scientific data generated by leading medical professionals and other experts in the field: people like Dr. Neal Barnard, founder and president of the Physicians Committee for Responsible Medicine, and T. Colin Campbell, professor emeritus of nutritional biochemistry at Cornell University and author of The China Study, a groundbreaking book published in 2005 that examines the close relationship between the consumption of animal proteins and the onset of chronic and degenerative illnesses such as cancer, heart disease, and obesity. In one of the largest epidemiological studies ever conducted, Professor Campbell and his peers determined that a plant-based, whole-food diet can minimize and actually reverse the development of these chronic diseases. Equally influential is Dr. Caldwell Esselstyn’s book Prevent and Reverse Heart Disease. A former surgeon at the Cleveland Clinic, as well as a Yale-trained rower who garnered Olympic gold at the 1956 Melbourne Summer Games, Dr. Esselstyn concludes from a twenty-year nutritional study that a plant-based, whole-food diet can not only prevent and stop the progression of heart disease, but also reverse its effects.

The word psychiatry derives from Greek roots meaning “soul doctoring”—a noble enterprise. Sadly, psychiatry today has lost touch with its roots. It is now dominated by the biomedical model, which attributes all disturbances of mental and emotional health to imbalances of brain biochemistry, correctable by medication. Big Pharma has taken great advantage of this by marketing an array of drugs to treat depression, anxiety, and major mental illnesses.

Putting terms aside, we’ll see that the ancient biosynthetic Krebs cycle was fixing CO2 a billion years before rubisco and the evolution of photosynthesis in the cyanobacterial ancestors of plant chloroplasts. When it first emerged, the reverse Krebs cycle had little to do with energy generation, instead providing the carbon skeletons needed for biosynthesis. This perspective elucidates the deep metabolism of cells, yet it is still largely missing from the more medically oriented textbooks. It’s a serious omission.

The medical cure for Corona Virus can be sought keeping in view the viral behaviour in bio-chemistry. But, the cure for purifying human soul lies in looking beyond viral, bacterial, cellular and animal behaviour and paying attention to goodness in behaviour urged by the conscience in human soul.

The night before a biochemistry class, I read the lecture notes from last year. I look at the pictures in the book. I read some of the book. Now, I've got the general concept. Sure...There's a couple of details to fill in and a few things to memorize. but that's no big deal. I've got the big picture and that's all I need. Bring it on professor. I'm ready. That's right. The next day, I'm a goalie sitting in the front row. Nothin gets past me... My ability to comprehend a biochemistry lecture just went up from 30% to 95%. I went on to score 780 out of a possible 800 on the medical school biochemistry boards exam (USMLE 1). Given that the 99th percentile began around 690, this was one of the highest scores in the USA, perhaps the highest.