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Four years ago, about 4,900 ninth grades began their high school career in the Boston Public schools. Today there are about 3,400 twelth graders. Nearly one third -- 1500 students -- have dropped out of the class in three and a half years. Almost half of the group that hopes to graduate (1,648) in six months' time has not passed the required standardized test (MCAS).
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Tony Wagner (Making the Grade: Reinventing America's Schools)
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like many MCAS patients, she had a complicated, virtually life-long history of multisystem unwellness of a generally inflammatory theme.
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Lawrence B. Afrin (Never Bet Against Occam: Mast Cell Activation Disease and the Modern Epidemics of Chronic Illness and Medical Complexity)
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It really all rides (see Chapter 27, Research Needs in MCAS) on whether we are able to confirm the preliminary findings reported twice now by Dr. Molderings’ group that mutations are commonly present in the mast cell regulatory elements of MCAS patients and that such mutations are the principal drivers of the aberrant mast cell activation in such patients.
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Lawrence B. Afrin (Never Bet Against Occam: Mast Cell Activation Disease and the Modern Epidemics of Chronic Illness and Medical Complexity)
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commonly found amongst the extensive problem lists most MCAS patients acquire as they meander through the halls of medicine in search of a sensible unifying explanation for their assorted ills.
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Lawrence B. Afrin (Never Bet Against Occam: Mast Cell Activation Disease and the Modern Epidemics of Chronic Illness and Medical Complexity)
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The severity of MCAS often permanently “steps up” to a higher baseline level following severe stress.
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Lawrence B. Afrin (Never Bet Against Occam: Mast Cell Activation Disease and the Modern Epidemics of Chronic Illness and Medical Complexity)
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many MCAS patients have been so ill for so long that they have come to accept various aspects of their illness as a baseline “healthy” (or at least “normal”) state for them.
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Lawrence B. Afrin (Never Bet Against Occam: Mast Cell Activation Disease and the Modern Epidemics of Chronic Illness and Medical Complexity)
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Hello Boeing 737 Max, goodbye world.
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Steven Magee