Lipid Profile Quotes

blood sugar values go down, blood pressure drops, chronic pain decreases or disappears, lipid profiles improve, inflammatory markers improve, energy increases, weight decreases, sleep is improved, IBS [irritable bowel syndrome] symptoms are lessened, etc. Medication is adjusted downward, or even eliminated, which reduces the side-effects for patients and the costs to society. The results we achieve with our patients are impressive and durable.

Most people now have the ‘LDL-C is bad and HDL-C is good’ concept down pat. But there is more to the story. It is well established that not all LDL particles are created equal. Moreover, certain types of LDL have been shown to correlate with abnormal lipid profiles and promote atherosclerosis. As noted previously, the larger more buoyant LDL particles are less harmful than smaller ones. Small LDL particles reside in the circulation longer, have greater susceptibility to oxidative damage by free radicals, and more easily penetrate the arterial wall, contributing to atherosclerosis. No matter what your total LDL-C concentration, if you have relatively more small particles (referred to as Pattern B) it puts you at a several-fold higher risk for heart disease compared to people with larger LDL particles (Pattern A)[49]. And once again, this is independent of your LDL-C concentration.

Part One—The Lipid Panel. Used to evaluate heart health, this panel comprises of four biological markers representing the four types of fat found in the blood—triglycerides, total cholesterol, high-density lipoprotein (HDL), and low-density lipoprotein (LDL). Two additional measures of cardiovascular health, homocysteine and c-reactive protein (CRP), may also be measured as part of a more comprehensive profile. These two labs are discussed in Part Six, “Optional Tests” (see page 8). •  Part Two—The Basic Metabolic Panel. The labs used to evaluate metabolism measure blood sugar regulation, electrolyte and fluid balance, and kidney function. Biomarkers included in this panel are glucose, calcium, sodium, potassium, blood urea nitrogen (BUN), and creatinine. •  Part Three—The Hepatic Function Panel. This panel determines how well your liver is functioning by measuring levels of different proteins produced and processed by the liver, like albumin and globulin, as well as liver enzymes. •  Part Four—The Complete Blood Count (CBC) Panel. The lab values measured in the complete blood count (CBC) panel include red blood cells, white blood cells, platelets, and hemoglobin. Maintaining healthy levels of these biomarkers affect your vitality and energy, immune system, and cardiovascular health. •  Part Five—Hormones. Although they are not always included in a routine blood test, hormones should be periodically tested, especially in aging adults. Hormones such as estrogen, testosterone, progesterone, DHEA, and prostate specific antigen (PSA) play an integral role in reproductive wellness and affect other aspects of health. Maintaining balanced levels can slow down the aging process, for instance. Hormones involved in metabolism, like the thyroid hormones and the stress hormone cortisol, are also discussed in this section. •  Part Six—Optional Tests. This final part of the book highlights four tests—homocysteine, c-reactive protein (CRP), vitamin D, and magnesium—that are not typically measured unless requested, or if a standard blood test shows an abnormality that requires a more in-depth analysis. These tests can provide a more complete picture of heart health, immunity, calcium absorption, blood sugar regulation, and a number of other vital processes.

The association between high triglycerides and heart disease is very well established. Even the National Lipid Association, from which this study and statement originate, acknowledges an independent association with triglycerides: “…triglycerides are the third component of the lipid profile and are an independent and compounding risk factor for heart disease, the leading cause of death in the U.S. Studies have shown that the risk of developing heart disease doubles when triglyceride levels are above 200 mg/dL. When triglycerides are above 200 mg/dL and HDL cholesterol is below 40 mg/dL, a person is at four times the risk of developing heart disease.

Estradiol—Estradiol is the strongest estrogen; it helps you think clearly. It is produced in the ovaries and has many protective effects, including maintaining bone density, improving growth hormone production and cardiovascular function, keeping your blood from getting “sticky,” supporting cognitive function and mood, assisting in growth hormone release, and improving your lipids profile. Too much estradiol can be associated with estrogen-related cancers, but deficiencies can lead to osteoporosis, heart disease, dementia, and other diseases of aging. Estradiol keeps you looking and feeling young and vibrant. It also provides antiaging protection for the skin. And it even helps prevent weight gain. Researchers at Yale University have found that estradiol suppresses appetite using the same pathways in the brain as leptin, which is one of the hormones that regulate appetite.

That’s the thing Neeti, most of us get put on medication a tad bit aggressively. By that I mean that we are put on medication the minute one blood test shows that TSH is higher than 5 and in some cases just higher than 3, even when t4 and t3 readings are in range, and also the lipid profile or the glycaemic control is measured as HbA1c. We start the medication in full faith but fail to correct the lifestyle factors that caused the TSH to go up in the first place. What is required really is extensive counselling for a complete lifestyle overhaul and that starts with one step

Here’s the list of the tests you need to make sure your doctor orders: lipid profile (LDL-C, HDL-C, TG), homocysteine (Hcy) level, alanine aminotransferase and aspartate aminotransferase (ALT and AST), uric acid, fasting insulin, fasting glucose, and hemoglobin A1c.

Once You’re in Keto, How Can You Keep It Going Without Fasting? The short answer is: Eat a boatload of fat (~1.5 to 2.5 g per kilogram of body weight), next-to-no carbs, and moderate protein (1 to 1.5 g per kilogram of body weight) each day. We’ll look at Dom’s typical meals and day in a minute, but a few critical notes first: High protein and low fat doesn’t work. Your liver will convert excess amino acids into glucose and shut down ketogenesis. Fat as 70 to 85% of calories is required. This doesn’t mean you always have to eat rib eye steaks. A chicken breast by itself will kick you out of ketosis, but a chicken breast cut up into a green leafy salad with a lot of olive oil, feta cheese, and some Bulletproof Coffee (for example) can keep you in ketosis. One of the challenges of keto is the amount of fat one needs to consume to maintain it. Roughly 70 to 80% of your total calories need to come from fat. Rather than trying to incorporate fat bombs into all meals (one does get tired of fatty steak, eggs, and cheese over and over again), Dom will both drink fat between meals (e.g., coconut milk—not water—in coffee) and add in supplemental “ice cream,” detailed on page 29. Dom noticed that dairy can cause lipid profile issues (e.g., can spike LDL) and has started to minimize things like cream and cheese. I experienced the same. It’s easy to eat a disgusting amount of cheese to stay in keto. Consider coconut milk (Aroy-D Pure Coconut Milk) instead. Dom doesn’t worry about elevated LDL as long as other blood markers aren’t out of whack (high CRP, low HDL, etc.). From Dom: “The thing that I focus on most is triglycerides. If your triglycerides are elevated, that means your body is just not adapting to the ketogenic diet. Some people’s triglycerides are elevated even when their calories are restricted. That’s a sign that the ketogenic diet is not for you. . . . It’s not a one-size-fits-all diet.

Beaudart, C., et al. (2017), Nutrition and physical activity in the prevention and treatment of sarcopenia: Systematic review, Osteoporosis International 28:1817–33; Lozano-Montoya, I. (2017), Nonpharmacological interventions to treat physical frailty and sarcopenia in older patients: A systematic overview—the SENATOR Project ONTOP Series, Clinical Interventions in Aging 12:721–40. 55. Fiatarone, M. A., et al. (1990), High-intensity strength training in nonagenarians: Effects on skeletal muscle, Journal of the American Medical Association 263:3029–34. 56. Donges, C. E., and Duffield, R. (2012), Effects of resistance or aerobic exercise training on total and regional body composition in sedentary overweight middle-aged adults, Applied Physiology, Nutrition, and Metabolism 37:499–509; Mann, S., Beedie, C., and Jimenez, A. (2014), Differential effects of aerobic exercise, resistance training, and combined exercise modalities on cholesterol and the lipid profile: Review, synthesis, and recommendations, Sports Medicine 44:211–21. 57. Phillips, S. M., et al. (1997), Mixed muscle protein synthesis and breakdown after resistance exercise in humans, American Journal of Physiology 273:E99–E107; McBride, J. M. (2016), Biomechanics of resistance exercise, in Haff and Triplett, Essentials of Strength Training and Conditioning, 19–42.

Pattern A and B are called lipid subfractions. Unfortunately, this test isn’t standardized and there are three competing methods: Ion Mobility (IM), Nuclear Magnetic Resonance (NMR), and Vertical Auto Profile (VAP). We prefer them in that order. They don’t yield identical results, but are close.

Insulin sensitivity is affected by zinc levels, so if yours is below 100, try 20 mg to 50 mg of zinc picolinate daily, then recheck your glucose after two months. High hemoglobin A1c reflects poor glucose control, which is affected by low magnesium. If your RBC magnesium is less than 5.2, try magnesium glycinate (500 mg per day) or magnesium threonate (2 g per day). Cinnamon turns out to be a wonderful way to improve glycemic control. You need only ¼ teaspoon each day, sprinkled on food, or you can easily take it as 1-gram capsules. Cinnamon also improves lipid profiles in people with type 2 diabetes.3 Alpha-lipoic acid is an antioxidant. Most people use 60 mg to 100 mg daily. Chromium picolinate also lowers blood glucose, and 400 micrograms to 1 milligram daily is the typical dosage. Berberine lowers blood glucose, and is usually taken at 300 to 500 milligrams three times per day. Your physician may also prescribe metformin to reduce blood glucose.

Laboratory Fatty liver disease ALT >25 in Caucasians, >20 in African Americans, >30 in Latinos GGT >35 Uric acid > 5.5 Glucose intolerance Fasting glucose > 100 or 2-hour glucose > 140; HbA1c > 6.0 percent Type 2 diabetes mellitus Fasting glucose > 125 or 2-hour glucose > 200; HbA1c > 6.5 percent Dyslipidemia and heart disease Lipid profile: TG > 150, HDL < 40, TG:HDL > 2.5, LDL-C >300, LDL-P >1000 Homocysteine > 15 Insulin resistance Fasting insulin > 15 Insulin hypersecretion 3-hour OGTT with insulin levels; measure insulin secretion and resistance indices