Instrumental Variables Quotes

What in water did Bloom, waterlover, drawer of water, watercarrier, returning to the range, admire? Its universality: its democratic equality and constancy to its nature in seeking its own level: its vastness in the ocean of Mercator's projection: its unplumbed profundity in the Sundam trench of the Pacific exceeding 8000 fathoms: the restlessness of its waves and surface particles visiting in turn all points of its seaboard: the independence of its units: the variability of states of sea: its hydrostatic quiescence in calm: its hydrokinetic turgidity in neap and spring tides: its subsidence after devastation: its sterility in the circumpolar icecaps, arctic and antarctic: its climatic and commercial significance: its preponderance of 3 to 1 over the dry land of the globe: its indisputable hegemony extending in square leagues over all the region below the subequatorial tropic of Capricorn: the multisecular stability of its primeval basin: its luteofulvous bed: its capacity to dissolve and hold in solution all soluble substances including millions of tons of the most precious metals: its slow erosions of peninsulas and islands, its persistent formation of homothetic islands, peninsulas and downwardtending promontories: its alluvial deposits: its weight and volume and density: its imperturbability in lagoons and highland tarns: its gradation of colours in the torrid and temperate and frigid zones: its vehicular ramifications in continental lakecontained streams and confluent oceanflowing rivers with their tributaries and transoceanic currents, gulfstream, north and south equatorial courses: its violence in seaquakes, waterspouts, Artesian wells, eruptions, torrents, eddies, freshets, spates, groundswells, watersheds, waterpartings, geysers, cataracts, whirlpools, maelstroms, inundations, deluges, cloudbursts: its vast circumterrestrial ahorizontal curve: its secrecy in springs and latent humidity, revealed by rhabdomantic or hygrometric instruments and exemplified by the well by the hole in the wall at Ashtown gate, saturation of air, distillation of dew: the simplicity of its composition, two constituent parts of hydrogen with one constituent part of oxygen: its healing virtues: its buoyancy in the waters of the Dead Sea: its persevering penetrativeness in runnels, gullies, inadequate dams, leaks on shipboard: its properties for cleansing, quenching thirst and fire, nourishing vegetation: its infallibility as paradigm and paragon: its metamorphoses as vapour, mist, cloud, rain, sleet, snow, hail: its strength in rigid hydrants: its variety of forms in loughs and bays and gulfs and bights and guts and lagoons and atolls and archipelagos and sounds and fjords and minches and tidal estuaries and arms of sea: its solidity in glaciers, icebergs, icefloes: its docility in working hydraulic millwheels, turbines, dynamos, electric power stations, bleachworks, tanneries, scutchmills: its utility in canals, rivers, if navigable, floating and graving docks: its potentiality derivable from harnessed tides or watercourses falling from level to level: its submarine fauna and flora (anacoustic, photophobe), numerically, if not literally, the inhabitants of the globe: its ubiquity as constituting 90 percent of the human body: the noxiousness of its effluvia in lacustrine marshes, pestilential fens, faded flowerwater, stagnant pools in the waning moon.

... since I was still, and must for long remain, in that period of life when one has not yet separated the fact of this sensual pleasure from the various women in whose company one has tasted it, when one has not reduced it to a general idea which makes one regard them thenceforward as the variable instruments of a pleasure that is always the same. Indeed, that pleasure does not exist, isolated and formulated in the consciousness, as the ultimate object with which one seeks a woman's company, or as the cause of the uneasiness which, in anticipation, one then feels. Hardly even does one think of oneself, but only how to escape from oneself.

The powerful effect of female literacy contrasts with the comparatively ineffective roles of, say, male literacy or general poverty reduction as instruments of child mortality reduction. The increase in male literacy over the same range (from 22 to 75 percent) only reduces under-five mortality from 169 per thousand to 141 per thousand. And a 50 percent reduction in the incidence of poverty (from the actual 1981 level) only reduces the predicted value of under-five mortality from 156 per thousand to 153 per thousand. Here again, the message seems to be that some variables relating to women's agency (in this case, female literacy) often play a much more important role in promoting social well-being (in particular, child survival) than variables relating to the general level of opulence in the society. These findings have important practical implications. Both types of variables can be influenced through public action, but respectively require rather different forms of public intervention.

I could believe this all the more readily (and also that the caresses by which she would bring that savour to my senses were themselves of a particular kind, yielding a pleasure which I could never derive from any but herself) since I was still, and must for long remain, in that period of life when one has not yet separated the fact of this sensual pleasure from the various women in whose company one has tasted it, when one has not reduced it to a general idea which makes one regard them thenceforward as the variable instruments of a pleasure that is always the same.

Despite the advancements of systematic experimental pipelines, literature-curated protein-interaction data continue to be the primary data for investigation of focused biological mechanisms. Notwithstanding the variable quality of curated interactions available in public databases, the impact of inspection bias on the ability of literature maps to provide insightful information remains equivocal. The problems posed by inspection bias extend beyond mapping of protein interactions to the development of pharmacological agents and other aspects of modern biomedicine. Essentially the same 10% of the proteome is being investigated today as was being investigated before the announcement of completion of the reference genome sequence. One way forward, at least with regard to interactome mapping, is to continue the transition toward systematic and relatively unbiased experimental interactome mapping. With continued advancement of systematic protein-interaction mapping efforts, the expectation is that interactome 'deserts', the zones of the interactome space where biomedical knowledge researchers simply do not look for interactions owing to the lack of prior knowledge, might eventually become more populated. Efforts at mapping protein interactions will continue to be instrumental for furthering biomedical research.

There was a single upright metal plate, wired to the grid of an enormous vacuum tube. Several smaller tubes behind the detector tube made the instrument more sensitive. "It works," explained Gerry, "like an electric variable condenser --" "But I say, it has only one wall. Surely all condensers have two." "Exactly. Only in this case the second wall is formed by any metallic body which comes within a certain range. When I switch on the current, there'll be a perfect electronic balance in the vacuum-tube set-up. It will be upset by the approach of any metal, which naturally changes the capacity. Any such change is registered on the dial here, and rings an alarm bell." "Very ingenious," drawled Michaels. "Especially for Venus, which is poor in metals. Don't worry, Miss Carlyle; we'll find Mr. Strike all right. That's a pretty tough lad to hurt.

In April 2014 a settlement agreement was reached in court, and Detroit had to pay $85 million to USB AG and Bank of America Corporation to terminate the swaps. The use of variable-rate instruments, such as swaps, to finance debt was the single "biggest contributing factor to the increase in Detroit's legacy expenses.

Whether playing an instrument or listening to the radio, music increases heart-rate variability, though making music has a stronger effect.4 Music engages most of the limbic system, including the hippocampus, anterior cingulate, and nucleus accumbens, which is why it can be motivating and enjoyable and can help regulate your emotions.5 It can also be soothing, lowering blood pressure6 and reducing stress.

The trouble with test-based accountability is that it imposes serious consequences on children, educators, and schools on the basis of scores that may reflect measurement error, statistical error, random variation, or a host of environmental factors or student attributes. None of us would want to be evaluated - with our reputation and livelihood on the line - solely on the basis of an instrument that is prone to error and ambiguity. The tests now in use are not adequate by themselves to the task of gauging the quality of schools or teachers ... they must be used with awareness of their limitations and variability. They were not designed to capture the most important dimensions of education, for which we do not have measures.

[...] it would be far simpler if we could limit ourselves to examining the chemistry and physiology of [the patient's] brain, and to treating mental events as objects alien to our immediate experience, or as mere variables of impersonal statistical formulae. Important as these approaches are for the understanding for human behavior, they cannot alone uncover or explain all the relevant facts.To see into the mind of another, we must repeatedly immerse ourselves in the flood of his associations and feelings; we must be ourselves the instrument that sounds him.

[...] it would be far simpler if we could limit ourselves to examining the chemistry and physiology of [the patient's] brain, and to treating mental events as objects alien to our immediate experience, or as mere variables of impersonal statistical formulae. Important as these approaches are for the understanding for human behavior, they cannot alone uncover or explain all the relevant facts. To see into the mind of another, we must repeatedly immerse ourselves in the flood of his associations and feelings; we must be ourselves the instrument that sounds him.

This has given rise to a misconception known as ‘Occam’s razor’ (named after the fourteenth-century philosopher William of Occam, but dating back to antiquity), namely that one should always seek the ‘simplest explanation’. One statement of it is ‘Do not multiply assumptions beyond necessity.’ However, there are plenty of very simple explanations that are nevertheless easily variable (such as ‘Demeter did it’). And, while assumptions ‘beyond necessity’ make a theory bad by definition, there have been many mistaken ideas of what is ‘necessary’ in a theory. Instrumentalism, for instance, considers explanation itself unnecessary, and so do many other bad philosophies of science, as I shall discuss in Chapter 12

Taking quick looks behind him on the trail, Lew Basnight was apt to see things that weren’t necessarily there. Mounted figure in a black duster and hat, always still, turned sidewise in the hard, sunlit distance, horse bent to the barren ground. No real beam of attention, if anything a withdrawal into its own lopsided star-shaped silhouette, as if that were all it had ever aspired to. It did not take long to convince himself that the presence behind him now, always just out of eyeball range, belonged to one and the same subject, the notorious dynamiter of the San Juans known as the Kieselguhr Kid. The Kid happened to be of prime interest to White City Investigations. Just around the time Lew was stepping off the train at the Union Station in Denver, and the troubles up in the Coeur d’Alene were starting to bleed over everywhere in the mining country, where already hardly a day passed without an unscheduled dynamite blast in it someplace, the philosophy among larger, city-based detective agencies like Pinkerton’s and Thiel’s began to change, being as they now found themselves with far too much work on their hands. On the theory that they could look at their unsolved cases the way a banker might at instruments of debt, they began selling off to less-established and accordingly hungrier outfits like White City their higher-risk tickets, including that of the long-sought Kieselguhr Kid. It was the only name anybody seemed to know him by, “Kieselguhr” being a kind of fine clay, used to soak up nitroglycerine and stabilize it into dynamite. The Kid’s family had supposedly come over as refugees from Germany shortly after the reaction of 1849, settling at first near San Antonio, which the Kid-to-be, having developed a restlessness for higher ground, soon left, and then after a spell in the Sangre de Cristos, so it went, heading west again, the San Juans his dream, though not for the silver-mine money, nor the trouble he could get into, both of those, he was old enough by then to appreciate, easy enough to come by. No, it was for something else. Different tellers of the tale had different thoughts on what. “Don’t carry pistols, don’t own a shotgun nor a rifle—no, his trade-mark, what you’ll find him packing in those tooled holsters, is always these twin sticks of dynamite, with a dozen more—” “Couple dozen, in big bandoliers across his chest.” “Easy fellow to recognize, then.” “You’d think so, but no two eyewitnesses have ever agreed. It’s like all that blasting rattles it loose from everybody’s memory.” “But say, couldn’t even a slow hand just gun him before he could get a fuse lit?” “Wouldn’t bet on it. Got this clever wind-proof kind of striker rig on to each holster, like a safety match, so all’s he has to do’s draw, and the ‘sucker’s all lit and ready to throw.” “Fast fuses, too. Some boys down the Uncompahgre found out about that just last August, nothin left to bury but spurs and belt buckles. Even old Butch Cassidy and them’ll begin to coo like a barn full of pigeons whenever the Kid’s in the county.” Of course, nobody ever’d been sure about who was in Butch Cassidy’s gang either. No shortage of legendary deeds up here, but eyewitnesses could never swear beyond a doubt who in each case, exactly, had done which, and, more than fear of retaliation—it was as if physical appearance actually shifted, causing not only aliases to be inconsistently assigned but identity itself to change. Did something, something essential, happen to human personality above a certain removal from sea level? Many quoted Dr. Lombroso’s observation about how lowland folks tended to be placid and law-abiding while mountain country bred revolutionaries and outlaws. That was over in Italy, of course. Theorizers about the recently discovered subconscious mind, reluctant to leave out any variable that might seem helpful, couldn’t avoid the altitude, and the barometric pressure that went with it. This was spirit, after all.