Influenza Quotes

This emotion I'm feeling now, this is love, right?" "I don't know. Is it a longing? Is it a giddy stupid happiness just because you're with me?" "Yes," she said. "That's influenza," said Miro. "Watch for nausea or diarrhea within a few hours.

Influenza killed more people in a year than the Black Death of the Middle Ages killed in a century; it killed more people in twenty-four weeks than AIDS has killed in twenty-four years.

The education bestowed on Flora Poste by her parents had been expensive, athletic and prolonged; and when they died within a few weeks of one another during the annual epidemic of the influenza or Spanish Plague which occurred in her twentieth year, she was discovered to possess every art and grace save that of earning her own living.

Society cannot function if it is every man for himself. By definition, civilization cannot survive that. Those in authority must retain the public's trust. The way to do that is to distort nothing, to put the best face on nothing, to try to manipulate no one.

She murmured, We could always blame the stars. I beg your pardon, Doctor? That's what influenza means, she said. Influenza delle stelle—the influence of the stars. Medieval Italians thought the illness proved that the heavens were governing their fates, that people were quite literally star-crossed. I pictured that, the celestial bodies trying to fly us like upsidedown kites. Or perhaps just yanking on us for their obscure amusement.

You don't manage the truth. You tell the truth.

Eat good dinners and drink good wine; read good novels if you have the leisure and see good plays; fall in love, if there is no reason why you should not fall in love; but do not pore over influenza statistics.

Consider how common illness is, how tremendous the spiritual change that it brings, how astonishing, when the lights of health go down, the undiscovered countries that are then disclosed, what wastes and deserts of the soul a slight attack of influenza brings to view, what precipices and lawns sprinkled with bright flowers a little rise of temperature reveals, what ancient and obdurate oaks are uprooted in us by the act of sickness, how we go down in the pit of death and feel the waters of annihilation close above our heads and wake thinking to find ourselves in the presence of the angels and the harpers when we have a tooth out and come to the surface in the dentist's arm-chair and confuse his "Rinse the mouth-rinse the mouth" with the greeting of the Deity stooping from the floor of Heaven to welcome us - when we think of this, as we are so frequently forced to think of it, it becomes strange indeed that illness has not taken its place with love and battle and jealousy among the prime themes of literature

The foundation of morality is to have done, once and for all, with lying.

Guai a coloro, dissi, che si servono dell'influenza che hanno su di un cuore per rapirgli le semplici gioie che esso sa procurare a se stesso!

Following this logic, the millions of people who perished during epidemics of influenza in the early twentieth century should have really pulled themselves together, instead of making all this fuss and dying in the most inconsiderate manner.

Do you think that they, with their Battles, Famine, Black Death and Serfdom, were less enlightened than we are, with our Wars, Blockade, Influenza, and Conscription.

I saw kids die of tuberculosis, influenza, pneumonia and broken hearts at St. Jerome’s.

Influenza delle stelle—the influence of the stars.

That’s what influenza means, she said. Influenza delle stelle—the influence of the stars. Medieval Italians thought the illness proved that the heavens were governing their fates, that people were quite literally star-crossed.

Teenage crush is like flu. If you find a remedy for it, it lasts for a couple of days. If you don't, it still lasts for a couple of days.

The two most important questions in science are “What can I know?” and “How can I know it?

The fear, not the disease, threatened to break the society apart.

The three most acute months of the Spanish influenza crisis left the survivors of Linares and of the whole world with scars that would never heal and voids that would never be filled.

What’s true of all the evils in the world is true of plague as well. It helps men to rise above themselves.

His hand was a claw, sharp enough to open her. She would be like all the others—Ruta Badowski, in her broken dancing shoes. Tommy Duffy, still with the dirt of his last baseball game under his nails. Gabriel Johnson, taken on the best day of his life. Or even Mary White, holding out for a future that never arrived. She’d be like all those beautiful, shining boys marching off to war, rifles at their hips and promises on their lips to their best girls that they’d be home in time for Christmas, the excitement of the game showing in their bright faces. They’d come home men, heroes with adventures to tell about, how they’d walloped the enemy and put the world right side up again, funneled it into neat lines of yes and no. Black and white. Right and wrong. Here and there. Us and them. Instead, they had died tangled in barbed wire in Flanders, hollowed by influenza along the Western Front, blown apart in no-man’s-land, writhing in trenches with those smiles still in place, courtesy of the phosgene, chlorine, or mustard gas. Some had come home shell-shocked and blinking, hands shaking, mumbling to themselves, following orders in some private war still taking place in their minds. Or, like James, they’d simply vanished, relegated to history books no one bothered to read, medals put in cupboards kept closed. Just a bunch of chess pieces moved about by unseen hands in a universe bored with itself.

In fact, biology is chaos. Biological systems are the product not of logic but of evolution, an inelegant process. Life does not choose the logically best design to meet a new situation. It adapts what already exists...The result, unlike the clean straight lines of logic, is often irregular, messy.

a spider and a fly i heard a spider and a fly arguing wait said the fly do not eat me i serve a great purpose in the world you will have to show me said the spider i scurry around gutters and sewers and garbage cans said the fly and gather up the germs of typhoid influenza and pneumonia on my feet and wings then i carry these germs into households of men and give them diseases all the people who have lived the right sort of life recover from the diseases and the old soaks who have weakened their systems with liquor and iniquity succumb it is my mission to help rid the world of these wicked persons i am a vessel of righteousness scattering seeds of justice and serving the noblest uses it is true said the spider that you are more useful in a plodding material sort of way than i am but i do not serve the utilitarian deities i serve the gods of beauty look at the gossamer webs i weave they float in the sun like filaments of song if you get what i mean i do not work at anything i play all the time i am busy with the stuff of enchantment and the materials of fairyland my works transcend utility i am the artist a creator and demi god it is ridiculous to suppose that i should be denied the food i need in order to continue to create beauty i tell you plainly mister fly it is all damned nonsense for that food to rear up on its hind legs and say it should not be eaten you have convinced me said the fly say no more and shutting all his eyes he prepared himself for dinner and yet he said i could have made out a case for myself too if i had had a better line of talk of course you could said the spider clutching a sirloin from him but the end would have been just the same if neither of us had spoken at all boss i am afraid that what the spider said is true and it gives me to think furiously upon the futility of literature archy

Shells, gas clouds, and flotillas of tanks - shattering, corroding, death. Dysentery, influenza, typhus - scalding, choking, death.

Every age has its signature afflictions. Thus, a bacterial age existed; at the latest, it ended with the discovery of antibiotics. Despite widespread fear of an influenza epidemic, we are not living in a viral age. Thanks to immunological technology, we have already left it behind. From a pathological standpoint, the incipient twenty-first century is determined neither by bacteria nor by viruses, but by neurons. Neurological illnesses such as depression, attention deficit hyperactivity disorder (ADHD), borderline personality disorder (BPD), and burnout syndrome mark the landscape of pathology at the beginning of the twenty-first century.

looked up and found the Great Bear. I told her, In Italy, they used to blame the influence of the constellations for making them sick—that’s where influenza comes from. Bridie took that notion in stride. As if, when it’s your time, your star gives you a yank—

influenza means, she said. Influenza delle stelle—the influence of the stars. Medieval Italians thought the illness proved that the heavens were governing their fates, that people were quite literally star-crossed.

Shut your eyes,” said Miss Tanner. “Oh no,” said Miranda, “for then I see worse things…

Our life alternates between billets and the front. We have almost grown accustomed to it; war is the cause of death like cancer and tuberculosis, like influenza and dysentery. The deaths are merely more frequent, more varied and terrible.

Considering how common illness is, how tremendous the spiritual change it brings, how astonishing, when the lights of health go down, the undiscovered countries that are then disclosed, what wastes and deserts of the soul a slight attack of influenza brings to view, what precipices and lawns sprinkled with bright flowers a little rise of temperature reveals, what ancient and obdurate oaks are uprooted in us by the act of sickness…it is strange indeed that illness has not taken its place with love and battle and jealousy among the prime themes of literature.” from her essay, On Being Ill

Awas! Cinta itu pembawa virus gila!

Epidemiologists have computed that measles requires an unvaccinated population of at least half a million people living in fairly close contact to continue to exist.

The influenza pandemic of 1918 killed more people than the First World War—an estimated 3 to 6 per cent of the human race.

How about a global pandemic? A novel strain of influenza for which we humans have no natural defense.

That’s what influenza means, she said. Influenza delle stelle—the influence of the stars.

The greatest single epidemic in human history was the one of influenza that killed 21 million people at the end of the First World War.

Poverty is apt to strike suddenly like influenza, it is well to have a few memories of extravagance in store for bad times.

I had an uneasy feeling we might be asked to spend the approaching Christmas with Beatrice. Perhaps I could have influenza.

The Spanish Influenza did not originate in Spain. In fact the first recorded case was in the United States, in Kansas, on March 9th, 1918. Beware the Ides of March. But because Spain was neutral in World War I, it did not sensor reports of the disease to the public. To tell the truth then, is to risk being remembered by its fiction. Countless countries laid blame to one another. What the US called the Spanish Influenza, Spain called the French Flu, or the Naples Soldier. What Germans dubbed the Russian Pest, the Russians called Chinese Flu.

Our life alternates between billets and the front. We have almost grown accustomed to it; war is the cause of death like cancer and tuberculosis, like influenza and dysentery. The deaths are merely

As terrifying the disease was, the press made it more so. They terrified by making little of it, for what officials and the press said bore no relationship to what people saw and touched and smelled and endured. People could not trust what they read. Uncertainty follows distrust, fear follow uncertainty, and, under conditions such as these, terror follows fear.

So the final lesson of 1918, a simple one yet one most difficult to execute, is that those who occupy positions of authority must lessen the panic that can alienate all within a society. Society cannot function if it is every man for himself. By definition, civilization cannot survive that. Those in authority must retain the public’s trust. The way to do that is to distort nothing, to put the best face on nothing, to try to manipulate no one. Lincoln said that first, and best. A leader must make whatever horror exists concrete. Only then will people be able to break it apart.

Ebola is a zoonosis. So is bubonic plague. So was the so-called Spanish influenza of 1918–1919, which had its ultimate source in a wild aquatic bird and, after passing through some combination of domesticated animals (a duck in southern China, a sow in Iowa?) emerged to kill as many as 50 million people before receding into obscurity.

Sit down before a fact as a little child, be prepared to give up every preconceived notion. Follow humbly wherever and to whatever abysses nature leads, or you shall learn nothing.” He also believed that learning had purpose, stating, “The great end of life is not knowledge but action.

No other disease, no war, no natural disaster, no famine comes close to the great pandemic. In the space of eighteen months in 1918–1919, about 500 million people, one-third of the human race at the time, came down with influenza. The exact total of lives lost will never be known. An early estimate, made in 1920, claimed 21.5 million died worldwide. Since then, researchers have been continually raising the number as they find new information. Today, the best estimate of flu deaths in 1918–1919 is between 50 million and 100 million worldwide, and probably closer to the latter figure. 7

biology is chaos. Biological systems are the product not of logic but of evolution, an inelegant process.

Emerson said that an institution is the lengthened shadow of one man,

He advised, “Whenever you fall, pick up something.

We today can recognize the antiquity of astrology in words such as disaster, which is Greek for “bad star,” influenza, Italian for (astral) “influence”; mazeltov, Hebrew—and, ultimately, Babylonian—for “good constellation,” or the Yiddish word shlamazel, applied to someone plagued by relentless ill-fortune, which again traces to the Babylonian astronomical lexicon. According to Pliny, there were Romans considered sideratio, “planet-struck.” Planets were widely thought to be a direct cause of death. Or consider consider: it means “with the planets,” evidently a prerequisite for serious reflection.

Yet institutions are human as well. They reflect the cumulative personalities of those within them, especially their leadership. They tend, unfortunately, to mirror less admirable human traits, developing and protecting self-interest and even ambition. Institutions almost never sacrifice. Since they live by rules, they lack spontaneity. They try to order chaos not in the way an artist or scientist does, through a defining vision that creates structure and discipline, but by closing off and isolating themselves from that which does not fit. They become bureaucratic.

Atahuallpa’s presence at Cajamarca thus highlights one of the key factors in world history: diseases transmitted to peoples lacking immunity by invading peoples with considerable immunity. Smallpox, measles, influenza, typhus, bubonic plague, and other infectious diseases endemic in Europe played a decisive role in European conquests, by decimating many peoples on other continents.

Hunger reduces one to an utterly spineless, brainless condition, more like the after-effects of influenza than anything else. It is as though one had been turned into a jellyfish, or as though all one’s blood had been pumped out and lukewarm water substituted.

There were no rules when it came to writing, he said. Take a close look at the lives of poets and novelists, and what you wound up with was unalloyed chaos, an infinite jumble of exceptions. That was because writing was a disease, Tom continued, what you might call an infection or influenza of the spirit, and therefore it could strike anyone at any time. The young and the old, the strong and the weak, the drunk and the sober, the sane and the insane. Scan the roster of the giants and semi-giants, and you would discover writers who embraced every sexual proclivity, every political bent, and every human attribute — from the loftiest idealism to the most insidious corruption. They were criminals and lawyers, spies and doctors, soldiers and spinsters, travelers and shut-ins.

The end of the war brought the closing of the borders cutting off Austria’s coal supply from Czechoslovakia, leaving the Austrians at peace but hungry, cold, and vulnerable to tuberculosis and a virulent form of influenza (Grosskurth, 1991, p. 82). Writer Stefan Zweig described postwar Vienna as “an uncertain, gray, and lifeless shadow of the former imperial monarchy” (qtd. in Gay, 1988, p. 380).

The influenza has busted me a good deal; I have no spring; and am headachy. So as my good Red Lion Counter begged me for another Butcher's Boy--I turned me to- what thinkest 'ou--to Tushery, by the mass! Ay, friend, a whole tale of tushery. And every tusher tushes me so free, that may I be tushed if the whole thing is worth a tush. The Black Arrow: A Tale of Tunstall Forest is his name: tush! a poor thing!

In the United States, influenza death rates were so high that the average life span fell by twelve years, from fifty-one in 1917 to thirty-nine in 1918. If you were a “doughboy”—slang for an American soldier—you had a better chance of dying in bed from flu or flu-related complications than from enemy action.

The dancing sickness took place during the latter part of the fifteenth century. Bubonic plague--the black death--decimated Europe near the end of the fourteenth. Whooping cough near the end of the seventeenth, and the first known outbreaks of influenza near the end of the nineteenth. We've become so used to the idea of the flu--it seems almost like the common cold to us, doesn't it?--that no one but the historians seem to know that a hundred years ago it didn't exist.

Certainty creates strength. Certainty gives one something upon which to lean. Uncertainty creates weakness. Uncertainty makes one tentative if not fearful, and tentative steps, even when in the right direction, may not overcome significant obstacles.

Throughout the pandemic, the nation lacked a uniform policy about gathering places, and there was no central authority with the power to make and enforce rules that everyone had to obey. Each community acted on its own, doing as its elected officials thought best.12

A randomized study by the American College of Physicians Public Health Emergency Collection published on June 24, 2020, concluded “randomized trials in community settings found possibly no difference between N95 versus surgical masks and probably no difference between surgical versus no mask in risk for influenza or influenza-like (respiratory) illness.”146

فيروس الزكام من السهل إلتقاطه لكن من الصعب العثور عليه !

Aveva abbandonato ogni piano d'azione; l'amore è la cosa migliore.

All positive knowledge obtained . . . has resulted from the accurate observation of facts.

When the next pandemic comes, as it surely will someday, perhaps we will be ready to meet it. If we are not, the outcome will be very, very, very dreadful.

Influenza. If you close your eyes and say the word aloud, it sounds lovely. It would make a good name for a pleasant, ancient Italian village.

Huxley did not look the warrior. But he had a warrior’s ruthlessness. His dicta included the pronouncement: “The foundation of morality is to have done, once and for all, with lying.

There comes a time when the fall of snow is no longer the start of a marvellous adventure. There comes a time when it means scraping your windscreen and hoping your car starts. It means aching joints and throbbing sinuses and cold hands and feet. It means taking longer to get to work and spending all day sitting in an office where the heating isn’t on. Grey slush and cracked pipes, cancelled trains and influenza, that’s what snow means. You’ll wake up feeling like that, one day, and it will mean you are grown up. I hope that day doesn’t come soon.

With influenza and many other diseases the order is reversed, high infectivity preceding symptoms by a matter of days. A perverse pattern: the danger, then the warning. That probably helped account for the scale of worldwide misery and death during the 1918–1919 influenza: high infectivity among cases before they experienced the most obvious and debilitating stages of illness.

We could always blame the stars. I beg your pardon, Doctor? That’s what influenza means, she said. Influenza delle stelle—the influence of the stars. Medieval Italians thought the illness proved that the heavens were governing their fates, that people were quite literally star-crossed. I pictured that, the celestial bodies trying to fly us like upside-down kites. Or perhaps just yanking on us for their obscure amusement

A zoonosis is an animal infection transmissible to humans. There are more such diseases than you might expect. AIDS is one. Influenza is a whole category of others. Pondering them as a group tends to reaffirm the old Darwinian truth (the darkest of his truths, well known and persistently forgotten) that humanity is a kind of animal, inextricably connected with other animals: in origin and in descent, in sickness and in health.

However, as bad as things were, the worst was yet to come, for germs would kill more people than bullets. By the time that last fever broke and the last quarantine sign came down, the world had lost 3-5% of its population.

For the influenza pandemic that erupted in 1918 was the first great collision between nature and modern science. It was the first great collision between a natural force and a society that included individuals who refused either to submit to that force or to simply call upon divine intervention to save themselves from it, individuals who instead were determined to confront this force directly, with a developing technology and with their minds.

Hamer was especially interested in why diseases such as influenza, diphtheria, and measles seem to mount into major outbreaks in a cyclical pattern—rising to a high case count, fading away, rising again after a certain interval

Aue sent an office boy with a message to the company’s original accountant, a Polish Jew named Itzhak Stern, who was at home with influenza. Aue was a political appointee with little accounting experience. He wanted Stern to come into the office and resolve the impasse over the bolts of linen. He had just sent the message off to Stern’s house in Podgórze when his secretary came into the office and announced that a Herr Oskar Schindler was waiting outside, claiming to have an appointment. Aue went into the outer room and saw a tall young man, placid as a large dog, tranquilly smoking. The two had met at a party the night before. Oskar had been there with a Sudeten German girl named Ingrid, Treuhänder, or supervisor, of a Jewish hardware company, just as Aue was Treuhänder of Buchheister’s. They were a glamorous couple, Oskar and this Ingrid, frankly in love, stylish, with lots of friends in the Abwehr.

Viruses are themselves an enigma that exist on the edges of life. They are not simply small bacteria. Bacteria consist of only one cell, but they are fully alive. Each has a metabolism, requires food, produces waste, and reproduces by division. Viruses do not eat or burn oxygen for energy. They do not engage in any process that could be considered metabolic. They do not produce waste. They do not have sex. They make no side products, by accident or design. They do not even reproduce independently. They are less than a fully living organism but more than an inert collection of chemicals.

Another explanation for the failure of logic and observation alone to advance medicine is that unlike, say, physics, which uses a form of logic - mathematics - as its natural language, biology does not lend itself to logic. Leo Szilard, a prominent physicist, made this point when he complained that after switching from physics to biology he never had a peaceful bath again. As a physicist he would soak in the warmth of a bathtub and contemplate a problem, turn it in his mind, reason his way through it. But once he became a biologist, he constantly had to climb out of the bathtub to look up a fact.

White Christians often explained the disaster in a time-honored way: it was God's punishment of humanity for its sings. To the seven deadly sins--anger, greed, lust, envy, pride, laziness, gluttony--they added an eighth sin: 'worshiping science.

And although better coverage of the outbreak’s evolution in the press couldn’t have stopped the influenza virus, a single newspaper headline in Philadelphia saying “Don’t Go to Any Parades; for the Love of God Cancel Your Stupid Parade” could have saved hundreds of lives. It would have done a lot more than those telling people, “Don’t Get Scared!” Telling people that things are fine is not the same as making them fine. This failure is in the past. Journalists and editors had their reasons. Risking jail time is no joke. But learning from this breakdown in truth-telling is important because the fourth estate can’t fail again. We are fortunate today to have organizations like the Centers for Disease Control and Prevention and the World Health Organization that track how diseases are progressing and report these findings. In the event of an outbreak similar to the Spanish flu, they will be wonderful resources. I hope we’ll be similarly lucky to have journalists who will be able to share necessary information with the public. The public is at its strongest when it is well informed. Despite Lippmann’s claims to the contrary, we are smart, and we are good, and we are always stronger when we work together. If there is a next time, it would be very much to our benefit to remember that.

overstate to make a point—warned, civilization could have disappeared within a few more weeks. So the final lesson of 1918, a simple one yet one most difficult to execute, is that those who occupy positions of authority must lessen the panic that can alienate all within a society. Society cannot function if it is every man for himself. By definition, civilization cannot survive that. Those in authority must retain the public’s trust. The way to do that is to distort nothing, to put the best face on nothing, to try to manipulate no one. Lincoln said that first, and best. A leader must make whatever horror exists concrete. Only then will people be able to break it apart.

When we think of a pandemic, we often conjure images of deadly infectious diseases that spread rapidly across countries causing unimaginable human suffering (like the Black Death, the Spanish influenza, AIDS, or the ongoing COVID-19 crisis). The West is currently suffering from such a devastating pandemic, a collective malady that destroys people’s capacity to think rationally. Unlike other pandemics where biological pathogens are to blame, the current culprit is composed of a collection of bad ideas, spawned on university campuses, that chip away at

But it’s not just me, you know. The whole world’s sad,” I said. “It’s like a virus. It’s going to end badly. Glaciers melting, ozone depleted. Terrorists blowing up buildings, nuclear rods infecting the aqueducts. Influenza hopping from the pigeons to the humans, killing millions. Billions. People rotting in the street. The sun bursting open, shattering us eight minutes later. If not that, starvation. Cannibalism. Freakish mutated babies with eyeballs in their navels. It’s a terrible place to bring a child into,” I said. “This world. It is terrible. Just terrible.” I

Surgeon General’s Advice to Avoid Influenza Avoid needless crowding. . . . Smother your coughs and sneezes. . . . Your nose not your mouth was made to breathe thru. . . . Remember the 3 Cs, clean mouth, clean skin, and clean clothes. . . . Food will win the war. . . . [H]elp by choosing and chewing your food well. . . . Wash your hands before eating. . . . Don’t let the waste products of digestion accumulate. . . . Avoid tight clothes, tight shoes, tight gloves—seek to make nature your ally not your prisoner. . . . When the air is pure breathe all of it you can—breathe deeply.

As it does today, malaria played a huge role in the past—a role unlike that of other diseases, and arguably larger. When Europeans brought smallpox and influenza to the Americas, they set off epidemics: sudden outbursts that shot through Indian towns and villages, then faded. Malaria, by contrast, became endemic, an ever-present, debilitating presence in the landscape. Socially speaking, malaria—along with another mosquito-borne disease, yellow fever—turned the Americas upside down. Before these maladies arrived, the most thickly inhabited terrain north of Mexico was what is now the southeastern United States, and the wet forests of Mesoamerica and Amazonia held millions of people. After malaria and yellow fever, these previously salubrious areas became inhospitable. Their former inhabitants fled to safer lands; Europeans who moved into the emptied real estate often did not survive a year.

Ho voglia di scuoterlo, di fargli capire che mi sono reso vulnerabile davanti a lui perché ho bisogno di sapere quello che mi nasconde, perché sono certo che questo suo segreto avrà un'influenza su noi due e ne ho paura. Ho paura di quello che provo per lui, paura di non essere pronto a questa separazione che si avvicina e che so essere inevitabile. Non mi riconosco più da quando è entrato nella mia vita e tutto questo mi fa paura. Questo non sono io, io non provo niente, io sfuggo le persone e la sorgente dei problemi che si trascinano dietro, non considero il mio futuro con qualcuno, non dico “ti amo.

Edward Jenner’s discovery of vaccination drew harsh criticism from the pulpit. Clergymen denounced the doctor for having put himself above God. Only the Almighty, they said, sends illness and only the Almighty cures it. Vaccination, critics charged, was “a diabolical operation,” and its inventor was “flying in the face of Providence

new influenza virus emerges, it is highly competitive, even cannibalistic. It usually drives older types into extinction. This happens because infection stimulates the body’s immune system to generate all its defenses against all influenza viruses to which the body has ever been exposed. When older viruses attempt to infect someone, they cannot gain a foothold. They cease replicating. They die out. So, unlike practically every other known virus, only one type—one swarm or quasi species—of influenza virus dominates at any given time. This itself helps prepare the way for a new pandemic, since the more time passes, the fewer people’s immune systems will recognize other antigens.

Several possibilities came to mind. 1. She was living in a suburb of the city of Utashinai on Hokkaido. 2. She had married and changed her name to 'Ito.' 3. She kept her number unlisted to protect her privacy. 4. She had died in the spring two years earlier from a virulent influenza. There must have been any number of possibilities beside these.

Influenza is caused by three types of viruses, of which the most worrisome and widespread is influenza A. Viruses of that type all share certain genetic traits: a single-stranded RNA genome, which is partitioned into eight segments, which serve as templates for eleven different proteins. In other words, they have eight discrete stretches of RNA coding, linked together like eight railroad cars, with eleven different deliverable cargoes. The eleven deliverables are the molecules that comprise the structure and functional machinery of the virus. They are what the genes make. Two of those molecules become spiky protuberances from the outer surface of the viral envelope: hemagglutinin and neuraminidase. Those two, recognizable by an immune system, and crucial for penetrating and exiting cells of a host, give the various subtypes of influenza A their definitive labels: H5N1, H1N1, and so on. The term “H5N1” indicates a virus featuring subtype 5 of the hemagglutinin protein combined with subtype 1 of the neuraminidase protein. Sixteen different kinds of hemagglutinin, plus nine kinds of neuraminidase, have been detected in the natural world. Hemagglutinin is the key that unlocks a cell membrane so that the virus can get in, and neuraminidase is the key for getting back out. Okay so far? Having absorbed this simple paragraph, you understand more about influenza than 99.9 percent of the people on Earth. Pat yourself on the back and get a flu shot in November. At

Her mother, an unshapely, chubby-cheeked creature from the rural gentry of Styria, permanently lost her hair at the age of forty after being treated for influenza by her husband, and prematurely withdrew from society. She and her husband were able to live in the Gentzgasse thanks to her mother's fortune, which derived from the family estates in Styria and then devolved upon her. She provided for everything, since her husband earned nothing as a doctor. He was a socialite, what is known as a beau, who went to all the big Viennese balls during the carnival season and throughout his life was able to conceal his stupidity behind a pleasingly slim exterior. Throughout her life Auersberger's mother-in-law had a raw deal from her husband, but was content to accept her modest social station, not that of a member of the nobility, but one that was thoroughly petit bourgeois. Her son-in-law, as I suddenly recalled, sitting in the wing chair, made a point of hiding her wig from time to time--whenever the mood took him--both in the Gentzgasse and at the Maria Zaal in Styria, so that the poor woman was unable to leave the house. It used to amuse him, after he had hidden her wig, to drive his mother-in-law up the wall, as they say. Even when he was going on forty he used to hide her wigs--by that time she has provided herself with several--which was a symptom of his sickness and infantility. I often witnessed this game of hide-and-seek at Maria Zaal and in the Gentzgasse, and I honestly have to say that I was amused by it and did not feel in the least bit ashamed of myself. His mother-in-law would be forced to stay at home because her son-in-law had hidden her wigs, and this was especially likely to happen on public holidays. In the end he would throw the wig in her face. He needed his mother-in-law's humiliation, I reflected, sitting in the wing chair and observing him in the background of the music room, just as he needed the triumph that this diabolical behavior brought him.

«Passi la vita a mercanteggiare?» rilancia sospirando. Sorrido ancora di più, e ancora non ha visto tutto. Mi raddrizzo per rispondergli. «Amo negoziare, la vita è fatta di negoziati, di compromessi, di scelte, di scambi e di esperienze. Secondo me, non si può avere l’uno senza avere l'altro. Guardaci, hai fatto la scelta di prendermi con te pur non avendo l'aria di un ragazzo che imbarca il primo venuto. Ho fatto un compromesso affinché non dovessimo litigare di brutto in ogni momento. Vedi, questo è solo una parte di quello che è la vita. Ma la vita è piena di stupidi, di imbecilli, di regole stereotipate su come devono essere gli uomini, come devono comportarsi, che aspetto devono avere, a quale categoria devono appartenere. Anche quello che compriamo è deciso dalla società che ci circonda. La vita è anche fatta di incontri interessanti, di delusioni, di amicizie, di amori, un lavoro, una famiglia, un passato, un futuro, e l'influenza che ha tutto questo mix di cose sul nostro presente. Qualche volta la vita è noiosa, imperfetta, dura e triste, ma è comunque appassionante. La vita è l'uomo, e studiare la vita dell'uomo, il suo comportamento, le situazioni, il sapere il come e il perché, è capire cosa genererà su qualcuno la scelta che ha fatto in un preciso istante. Tutto questo è appassionante. La vita è appassionante, Travis, e sì, amo mercanteggiare, amo scambiare, e vivere di esperienze. Forse mi sono un po’ perso… ma sono così, parlo, parlo, spesso vado troppo lontano, e faccio fatica a fermarmi»

No medicine and none of the vaccines developed then could prevent influenza. The masks worn by millions were useless as designed and could not prevent influenza. Only preventing exposure to the virus could. Nothing today can cure influenza, although vaccines can provide significant—but nowhere near complete—protection, and several antiviral drugs can mitigate its severity. Places that isolated themselves—such as Gunnison, Colorado, and a few military installations on islands—escaped. But the closing orders that most cities issued could not prevent exposure; they were not extreme enough. Closing saloons and theaters and churches meant nothing if significant numbers of people continued to climb onto streetcars, continued to go to work, continued to go to the grocer. Even where fear closed down businesses, where both store owners and customers refused to stand face-to-face and left orders on sidewalks, there was still too much interaction to break the chain of infection. The virus was too efficient, too explosive, too good at what it did. In the end the virus did its will around the world.

When Franklin D. Roosevelt signed the Social Security Act in 1935, old age was defined as sixty-five years, yet estimated life expectancy in the United States at the time was sixty-one years for males and sixty-four years for females.62 A senior citizen today, however, can expect to live eighteen to twenty years longer. The downside is that he or she also should expect to die more slowly. The two most common causes of death in 1935 America were respiratory diseases (pneumonia and influenza) and infectious diarrhea, both of which kill rapidly. In contrast, the two most common causes of death in 2007 America were heart disease and cancer (each accounted for about 25 percent of total deaths). Some heart attack victims die within minutes or hours, but most elderly people with heart disease survive for years while coping with complications such as high blood pressure, congestive heart failure, general weakness, and peripheral vascular disease. Many cancer patients also remain alive for several years following their diagnosis because of chemo-therapy, radiation, surgery, and other treatments. In addition, many of the other leading causes of death today are chronic illnesses such as asthma, Alzheimer’s, type 2 diabetes, and kidney disease, and there has been an upsurge in the occurrence of nonfatal but chronic illnesses such as osteoarthritis, gout, dementia, and hearing loss.63 Altogether, the growing prevalence of chronic illness among middle-aged and elderly individuals is contributing to a health-care crisis because the children born during the post–World War II baby boom are now entering old age, and an unprecedented percentage of them are suffering from lingering, disabling, and costly diseases. The term epidemiologists coined for this phenomenon is the “extension of morbidity.

This is something that has been going on forever,” Craig Spencer, the director of global health in emergency medicine at Columbia University, says about the variability of human response to infection. “I wouldn’t be surprised if people are walking about with long Epstein-Barr virus, or long influenza. We all know someone who is low energy, who’s told to work harder. We have all heard about chronic Lyme sufferers, and those with ME/CFS. But they get written off.” Spencer understands something about how infections can do long-term damage, because he contracted Ebola while working in Guinea, fell ill upon his return to New York City, and then struggled with the virus’s ongoing effects. (Studies have suggested that the Ebola virus may linger in the body for years.) The difference between long COVID and other infection-associated illnesses is that it is happening “on such a huge scale—unlike anything we’ve seen before. It is harder for the medical community to write off,” Spencer told me. Indeed, many researchers I spoke with for this book hope that the race to understand long COVID will advance our understanding of other chronic conditions that follow infection, transforming medicine in the process.

increases of the infectivity rate may lead to large epidemics.” This quiet warning has echoed loudly ever since. It’s a cardinal truth, over which public health officials obsess each year during influenza season. Another implication was that epidemics don’t end because all the susceptible individuals are either dead or recovered. They end because susceptible individuals are no longer sufficiently dense within the population. W. H. Hamer had said so in 1906, remember? Ross had made the same point in 1916. But the paper by Kermack and McKendrick turned it into a working principle of mathematical epidemiology.

in a letter to the New York Times, Dr. Hans Neumann from the New Haven Department of Health noted that based on the projected scale of the immunizations, within two days of getting a flu shot, about 2,300 people would have a stroke and 7,000 would have a heart attack. “Why?” he asked. “Because that is the number statistically expected, flu shots or no flu shots.” Likewise, in the week following a flu vaccine, another 9,000 people would contract pneumonia, of whom 900 would die. These would certainly occur after a flu shot, but not as a consequence of it. “Yet,” wrote Neumann, “can one expect a person who received a flu shot at noon and who that same night had a stroke not to associate somehow the two in his mind?” Grandma got the flu vaccine in the morning, and she was dead in the afternoon. Although association does not equal causation, this thinking could lead to a public backlash against vaccinations that would threaten future programs.

On the landing yesterday’s poster hooked my attention ‘Would they be dead if they’d stayed in bed?’ I had an impulse to rip it down, but that probably constituted conduct unbecoming to a nurse, as well as treason. ‘Yes, they’d be bloody dead,’ I ranted silently. ‘Dead in their beds or at the kitchen table eating their onion a day. Dead on the tram, falling down in the street, whenever the bone-man happened to catch up with them. Blame the germs, the unburied corpses, the dust of war, the circulation of wind and weather, but Lord God Almighty, blame the stars, just don’t blame the dead, because none of them wished this on themselves.

Flu pandemics are nothing new. Medical historians think the first one struck in 1510, infecting Asia, Africa, Europe, and the New World. Between the years 1700 and 1900, there were at least sixteen pandemics, some of them killing up to one million people. Yet these were tame compared to the 1918 calamity. It was by far the worst thing that has ever happened to humankind; not even the Black Death of the Middle Ages comes close in the number of lives it took. A 1994 report by the World Health Organization pulled no punches. The 1918 pandemic, it said, “killed more people in less time than any other disease before or since.” It was the “most deadly disease event in the history of humanity.

relationship with nature, modern humanity has generally been the aggressor, and a daring one at that, altering the flow of rivers, building upon geological faults, and, today, even engineering the genes of existing species. Nature has generally been languid in its response, although contentious once aroused and occasionally displaying a flair for violence. By 1918 humankind was fully modern, and fully scientific, but too busy fighting itself to aggress against nature. Nature, however, chooses its own moments. It chose this moment to aggress against man, and it did not do so prodding languidly. For the first time, modern humanity, a humanity practicing the modern scientific method, would confront nature in its fullest rage.

On Sunday, November 10, Kaiser Wilhelm II was dethroned, and he fled to Holland for his life. Britain’s King George V, who was his cousin, told his diary that Wilhelm was “the greatest criminal known for having plunged the world into this ghastly war,” having “utterly ruined his country and himself.” Keeping vigil at the White House, the President and First Lady learned by telephone, at three o’clock that morning, that the Germans had signed an armistice. As Edith later recalled, “We stood mute—unable to grasp the significance of the words.” From Paris, Colonel House, who had bargained for the armistice as Wilson’s envoy, wired the President, “Autocracy is dead. Long live democracy and its immortal leader. In this great hour my heart goes out to you in pride, admiration and love.” At 1:00 p.m., wearing a cutaway and gray trousers, Wilson faced a Joint Session of Congress, where he read out Germany’s surrender terms. He told the members that “this tragical war, whose consuming flames swept from one nation to another until all the world was on fire, is at an end,” and “it was the privilege of our own people to enter it at its most critical juncture.” He added that the war’s object, “upon which all free men had set their hearts,” had been achieved “with a sweeping completeness which even now we do not realize,” and Germany’s “illicit ambitions engulfed in black disaster.” This time, Senator La Follette clapped. Theodore Roosevelt and Senator Lodge complained that Wilson should have held out for unconditional German surrender. Driven down Capitol Hill, Wilson was cheered by joyous crowds on the streets. Eleanor Roosevelt recorded that Washington “went completely mad” as “bells rang, whistles blew, and people went up and down the streets throwing confetti.” Including those who had perished in theaters of conflict from influenza and other diseases, the nation’s nineteen-month intervention in the world war had levied a military death toll of more than 116,000 Americans, out of a total perhaps exceeding 8 million. There were rumors that Wilson planned to sail for France and horse-trade at the peace conference himself. No previous President had left the Americas during his term of office. The Boston Herald called this tradition “unwritten law.” Senator Key Pittman, Democrat from Nevada, told reporters that Wilson should go to Paris “because there is no man who is qualified to represent him.” The Knickerbocker Press of Albany, New York, was disturbed by the “evident desire of the President’s adulators to make this war his personal property.” The Free Press of Burlington, Vermont, said that Wilson’s presence in Paris would “not be seemly,” especially if the talks degenerated into “bitter controversies.” The Chattanooga Times called on Wilson to stay home, “where he could keep his own hand on the pulse of his own people” and “translate their wishes” into action by wireless and cable to his bargainers in Paris.

It may seem paradoxical to claim that stress, a physiological mechanism vital to life, is a cause of illness. To resolve this apparent contradiction, we must differentiate between acute stress and chronic stress. Acute stress is the immediate, short-term body response to threat. Chronic stress is activation of the stress mechanisms over long periods of time when a person is exposed to stressors that cannot be escaped either because she does not recognize them or because she has no control over them. Discharges of nervous system, hormonal output and immune changes constitute the flight-or-fight reactions that help us survive immediate danger. These biological responses are adaptive in the emergencies for which nature designed them. But the same stress responses, triggered chronically and without resolution, produce harm and even permanent damage. Chronically high cortisol levels destroy tissue. Chronically elevated adrenalin levels raise the blood pressure and damage the heart. There is extensive documentation of the inhibiting effect of chronic stress on the immune system. In one study, the activity of immune cells called natural killer (NK) cells were compared in two groups: spousal caregivers of people with Alzheimer’s disease, and age- and health-matched controls. NK cells are front-line troops in the fight against infections and against cancer, having the capacity to attack invading micro-organisms and to destroy cells with malignant mutations. The NK cell functioning of the caregivers was significantly suppressed, even in those whose spouses had died as long as three years previously. The caregivers who reported lower levels of social support also showed the greatest depression in immune activity — just as the loneliest medical students had the most impaired immune systems under the stress of examinations. Another study of caregivers assessed the efficacy of immunization against influenza. In this study 80 per cent among the non-stressed control group developed immunity against the virus, but only 20 per cent of the Alzheimer caregivers were able to do so. The stress of unremitting caregiving inhibited the immune system and left people susceptible to influenza. Research has also shown stress-related delays in tissue repair. The wounds of Alzheimer caregivers took an average of nine days longer to heal than those of controls. Higher levels of stress cause higher cortisol output via the HPA axis, and cortisol inhibits the activity of the inflammatory cells involved in wound healing. Dental students had a wound deliberately inflicted on their hard palates while they were facing immunology exams and again during vacation. In all of them the wound healed more quickly in the summer. Under stress, their white blood cells produced less of a substance essential to healing. The oft-observed relationship between stress, impaired immunity and illness has given rise to the concept of “diseases of adaptation,” a phrase of Hans Selye’s. The flight-or-fight response, it is argued, was indispensable in an era when early human beings had to confront a natural world of predators and other dangers. In civilized society, however, the flight-fight reaction is triggered in situations where it is neither necessary nor helpful, since we no longer face the same mortal threats to existence. The body’s physiological stress mechanisms are often triggered inappropriately, leading to disease. There is another way to look at it. The flight-or-fight alarm reaction exists today for the same purpose evolution originally assigned to it: to enable us to survive. What has happened is that we have lost touch with the gut feelings designed to be our warning system. The body mounts a stress response, but the mind is unaware of the threat. We keep ourselves in physiologically stressful situations, with only a dim awareness of distress or no awareness at all.