Immunotherapy Quotes

If you change the way you look at things, the things you look at change. -Max Planck

Chance favors the prepared mind. - Louis Pasteur

You believed, or you didn't; it all came down to which studies you chose to believe, and how you decided to interpret them.

Then, too, while gene editing is capable of repairing DNA in cultured human cells, it will be years before its efficacy is (or is not) demonstrated in human patients, and the few clinical successes that have been achieved so far with cancer immunotherapy and HIV might or might not be accurate predictors of other successes to come.

You can visit the department of allergy & immunotherapy at MyBaby Hospital if you are looking for allergy asthma specialist in Jaipur for your child’s treatment. The specialists here hold great experience in treating all kinds of child problems. They provide the most suitable treatment and medications after analysing and diagnosing the health of the patient.

A month later Dr. Cartwright sends me a note of congratulations. He has been able to make an arrangement with Merck, the pharmaceutical giant, for access to the immunotherapy drug here at Duke, and the news fills me with a bright hope. No more 3:45 a.m. wakeups. No more hours on the phone with airline companies, trying to fix a haywire flight--- or relying on donations to afford the flights in the first place. A painful chapter of my life will finally close.

You have another young patient on immunotherapy? Here at Duke?" I repeat slowly, as Dr. Cartwright chats amicably about how he managed to secure the same drug for him too. Months ago. Months I have spent traveling to Atlanta, whittling down my family's savings and relying on the charity of others. Months of arguing with insurance companies---because treatment was administered out of state---contesting payments and fielding phone calls with bill collectors over clerical errors. I have been hooked to a bag of chemotherapy fluid that could have been administered by pills? I have been getting on a plane when I could have been walking down the hallway in my own institution?

It can be challenging to decipher what causes fatigue. One way to understand fatigue during immunotherapy is to look at it as a natural consequence of the way in which immunotherapy works (Abdel-Rahmen et al, 2016). Think back to the last time you were sick with a bad cold or stomach bug. You probably spent a large portion of your day in bed, feeling exhausted. Being tired when we’re sick is common, and even adaptive; when our immune system works hard, our body shifts our energy resources to prioritize the healing process. As you’ve learned, immunotherapy works by enhancing our immune system so that it can successfully fight cancer. Therefore, it makes sense that fatigue should accompany this process.

immunotherapy making use of Lymphokine Activated Killer Cells. These LAK cells, as they became known, were derived from a patient’s own blood. When grown in the laboratory with some special proteins, they had the ability to selectively attack solid tumor cancers, regardless of type, and destroy them with only minimal side effects. In short, it was the ideal treatment for persons afflicted with this terrible disease. “Unfortunately, there were two problems; only thirty-nine percent of the patients treated responded to the therapy, and the process of collecting and growing the killer cells in the laboratory was time consuming and incredibly expensive. Then, with Doctor Steinberg’s death, and the drying up of government funding, this work at NIH ceased.

Long story short: The next three and a half years were a blur of treatment and recovery, with occasional flashes of hope illuminating dark tunnels of anxiety. She had surgery to remove her infected lymph nodes and the metastases in her liver and stomach. The surgery was followed by radiation, which was excruciating, turning her skin black in places and leaving behind nasty scars to go with the ones she’d collected in the operating room. She also learned there were different kinds of melanoma, even for those with stage IV, which led to different treatment options. In her case, that meant immunotherapy, which seemed to work for a couple of years, until it finally didn’t.

But with antibiotics and technology came great expectations, of being able to keep our children safe, of living long and healthy lives, relaxed and content and able to keep up the car payments. Even with the Internet, deciphering the genetic code, and great advances in immunotherapy, life is frequently confusing at best, and guaranteed to be hard and weird and sad at times.

P2 - We are well on the way in a number of areas. Both billionaires and big Pharma are getting increasingly interested and money is starting to pour into research because it is clear we can see the light at the end of the tunnel which to investors equates to return on investment. Numerous factors will drive things forward and interest and awareness is increasing rapidly among both scientists, researchers and the general population as well as wealthy philanthropists. The greatest driving force of all is that the baby boomers are aging and this will place increasing demands on healthcare systems. Keep in mind that the average person costs more in medical expenditure in the last year of their life than all the other years put together. Also, the number of workers is declining in most developed countries which means that we need to keep the existing population working and productive as long as possible. Below are a list which are basically all technologies potentially leading to radical life extension with number 5 highlighted which I assume might well be possible in the second half of the century: 1. Biotechnology - e.g stem cell therapies, enhanced autophagy, pharmaceuticals, immunotherapies, etc 2. Nanotechnology - Methods of repairing the body at a cellular and molecular level such as nanobots. 3. Robotics - This could lead to the replacement of increasing numbers of body parts and tends to go hand in hand with AI and whole brain emulation. It can be argued that this is not life extension and that it is a path toward becoming a Cyborg but I don’t share that view because even today we don’t view a quadriplegic as less human if he has four bionic limbs and this will hold true as our technology progresses. 4. Gene Therapies - These could be classified under the first category but I prefer to look at it separately as it could impact the function of the body in very dramatic ways which would suppress genes that negatively impact us and enhance genes which increase our tendency toward longer and healthier lives. 5. Whole brain emulation and mindscaping - This is in effect mind transfer to a non biological host although it could equally apply to uploading the brain to a new biological brain created via tissue engineering this has the drawback that if the original brain continues to exist the second brain would have a separate existence in other words whilst you are identical at the time of upload increasing divergence over time will be inevitable but it means the consciousness could never die provided it is appropriately backed up. So what is the chance of success with any of these? My answer is that in order for us to fail to achieve radical life extension by the middle of the century requires that all of the above technologies must also fail to progress which simply won't happen and considering the current rate of development which is accelerating exponentially and then factoring in that only one or two of the above are needed to achieve life extension (although the end results would differ greatly) frankly I can’t see how we can fail to make enough progress within 10-20 years to add at least 20 to 30 years to current life expectancy from which point progress will rapidly accelerate due to increased funding turning aging at the very least into a manageable albeit a chronic incurable condition until the turn of the 22nd century. We must also factor in that there is also a possibility that we could find a faster route if a few more technologies like CRISPR were to be developed. Were that to happen things could move forward very rapidly. In the short term I'm confident that we will achieve significant positive results within a year or two in research on mice and that the knowledge acquired will then be transferred to humans within around a decade. According to ADG, a dystopian version of the post-aging world like in the film 'In Time' not plausible in the real world: "If you CAREFULLY watch just the first

depression. It can be challenging to decipher what causes fatigue. One way to understand fatigue during immunotherapy is to look at it as a natural consequence of the way in which immunotherapy works (Abdel-Rahmen et al, 2016). Think back to the last time you were sick with a bad cold or stomach bug. You probably spent a large portion of your day in bed, feeling exhausted. Being tired when we’re sick is common, and even adaptive; when our immune system works hard, our body shifts our energy resources to prioritize the healing process. As you’ve learned, immunotherapy works by enhancing our immune system so that it can successfully fight cancer. Therefore, it makes sense that fatigue should accompany this process.

Fundamental mysteries remained, of course. How this system achieved the acrobatic balancing act between generating a forceful immune response against pathogens, while ensuring that same response did not turn on our own bodies—how the Kampf against microbial invaders did not degenerate into the civil war of horror autotoxicus—was still somewhat of a profound riddle (in Sam P.’s case, we could never control the autoimmune hepatitis induced by the cancer-rejecting immunotherapy).

Saturate the body politic with the chemotherapy or immunotherapy of antiracist policies that shrink the tumors of racial inequities, that kill undetectable cancer cells. Remove any remaining racist policies, the way surgeons remove the tumors. Ensure there are clear margins, meaning no cancer cells of inequity left in the body politic, only the healthy cells of equity. Encourage the consumption of healthy foods for thought and the regular exercising of antiracist ideas, to reduce the likelihood of a recurrence. Monitor the body politic closely, especially where the tumors of racial inequity previously existed. Detect and treat a recurrence early, before it can grow and threaten the body politic.

Right now, there are only two hospitals in the world that offer the Gerson Therapy, though there are countless centers that have integrated its nutrition and detox plan into their kitchens and protocols. One is located in Mexico. The other is in Hungary. Why only two? The reasons for this are…very complicated. When it comes to cancer, physicians in North America are legally obligated to recommend chemo, surgery, radiation, or sometimes gene therapy or immunotherapy.

As I wrote in my original report, “we have learned the immune system is not static, it changes with age according to environmental toxins, infections, and vaccinations. Vaccines are immunotherapy. That is, they are designed to alter the immune response to an antigen/infection. We have long recognized that the reasons some individuals react badly to immunotherapies, including vaccines, while the majority of people who are treated/vaccinated do not, has much to do with the recipient’s genetics and the status of the recipient’s health and immune system at the time of administration of the immunotherapy/vaccination.”12

today the idea of interrupting the dialogue between the tumor and its host environment underlies targeted therapy, immunotherapy, and nearly every active cancer research program. The company that developed Avastin was called Genentech. Between the day the company first announced the data and the day the FDA approved the drug, its market value increased by $38 billion, a rough measure of the value of the drug. (Folkman owned no stock in the company; he routinely donated any financial stakes and prize money he received to his hospital.) Later, Folkman would say, “You can tell a leader by counting the number of arrows in his ass.

The potential utility of therapeutic gene editing goes far beyond simply reverting mutated genes back to their healthy states. Some scientists are employing CRISPR in human cells to block viral infections, just like this molecular defense system naturally evolved to do in bacteria. In fact, the first clinical trials to use gene editing are aimed at curing HIV/AIDS by editing a patient’s own immune cells so the virus can’t penetrate them. And in another landmark effort, the first human life was saved by gene editing in combination with another emerging breakthrough in medicine: cancer immunotherapy, in which the body’s own immune system is trained to hunt down and kill cancerous cells.

the Omegas harnessed Prometheus to revolutionize education. Given any person’s knowledge and abilities, Prometheus could determine the fastest way for them to learn any new subject in a manner that kept them highly engaged and motivated to continue, and produce the corresponding optimized videos, reading materials, exercises and other learning tools. Omega-controlled companies therefore marketed online courses about virtually everything, highly customized not only by language and cultural background but also by starting level. Whether you were an illiterate forty-year-old wanting to learn to read or a biology PhD seeking the latest about cancer immunotherapy, Prometheus had the perfect course for you. These offerings bore little resemblance to most present-day online courses: by leveraging Prometheus’ movie-making talents, the video segments would truly engage, providing powerful metaphors that you would relate to, leaving you craving to learn more. Some courses were sold for profit, but many were made available for free, much to the delight of teachers around the world who could use them in their classrooms—and to most anybody eager to learn anything.

Saturate the body politic with the chemotherapy or immunotherapy of antiracist policies that shrink the tumors of racial inequities, that kill undetectable cancer cells. Remove any remaining racist policies, the way surgeons remove the tumors. Ensure there are clear margins, meaning no cancer cells of inequity left in the body politic, only the healthy cells of equity.

Belinda Lennox had found patients whose psychiatric symptoms were caused by the immune system attacking the mind. The disease was hiding in plain sight. When Dr Najjar correctly diagnosed Susannah Cahalan in 2009, he guessed that roughly 90 per cent of those with anti-NMDA encephalitis were undiagnosed. The general consensus today is that this percentage is probably lower, but it’s still highly likely that the number of misdiagnosed cases still heavily outweighs those successfully treated. A whole decade on from Susannah Cahalan’s case, when Samantha Raggio started to believe that a Mexican drug cartel was after her family, it still took numerous reviews by medical professionals to reach the correct diagnosis. We can be certain that there are individuals with this disease today who, misdiagnosed, are missing out on life-saving treatment. As Susannah writes in her memoir, ‘How many people currently are in psychiatric wards and nursing homes, denied the relatively simple cure of steroids, plasma exchange or more intense immunotherapy?