Hype Me Up Quotes

I doubt you’ve ever been forced to nonstop bang a woman hyped up on the undead voodoo version of Spanish fly, have you?” His chuckle was soft. “Can’t say that I have, Kitten.” “Yeah, well, consider me an original.” This time, when his lips brushed across my skin, it lasted more than a moment. “I always have.

This looks like the red room of pain,” she says.  My mouth drops open. My little prude has been expanding her reading horizons. I choke on my laugh, and a couple of people turn to look at us. I narrow my eyes.  “You read Fifty?” I ask quietly. She blushes. Amazing! — the woman is capable of blushing.  “Everyone was reading it,” she says, defensively. Then she looks up at me with big eyes.  “You?”  “I wanted to see what all the hype was about.” She does that blink, blink, blink thing with her eyelashes.  “Did you pick up any new techniques?” she says, without looking at me. I squeeze her hand. “Would you like to try me out and see?” She turns her face away, pressing her lips together — horribly embarrassed. 

I reached for a Coca-Cola. “Want some?” I asked. “I do not drink caffeine,” he said. “Wow, you make me look like a bad girl; that's hard to do.” He cracked a big smile for the first time I'd seen, and a huge dimple appeared in his right cheek. A butterfly wing flapped in my stomach. I turned my attention back to the drinks, fumbling a little for a cup. “Don't let me pressure you,” I said. “I was only kidding. We don't need you all hyped up on caffeine. How about ginger ale instead?" “Is that drink not only for upset stomachs?

These things—I call them my “tornado explosions”— are pieces of me. All the stuff that does not work gets balled up and hyped up. I can’t stop, even though I want to, even though I know I’m freaking people out. I lose myself. It can get kinda ugly. Once,

I just don’t get all the hype around pretty people. I get why they exist—for meet-cute purposes, for magazine spreads—but they’re just so stressful to be around. Who needs that kind of stress in their life? Not me.

For as much as many NKOTB fans have been caught off guard by how much this has all meant, so too have some of the guys. Donnie says, "It was a surprise to me how fulfilling it was. It was a surprise to me how emotional it was, how rewarding it was. And quite frankly, how wrapped up in the fans I am. I'm not caught up in the hype. I don't need it. I don't need some fulfillment. I can live without it. But I don't want to. I love making people smile. I love sharing myself. I love the feeling of making people happy. I love the fact that, for whatever reason, I've been put in a position to change people's lives in a simple way. I'm not healing diseases. But I can make someone happy, even for a short time.

This writing thing, it ain’t like that hip hop shit, City. For li’l niggas like you,” he told me, “this writing thing is like a gotdamn porta potty. It’s one li’l nigga at a time, shitting in the toilet, funking up the little space he get. And you shit a regular shit or a classic shit. Either way,” he said. “City, you gotta shit classic, then get your black ass on off the pot.” He actually grabbed my hand. “You probably think I’m hyping you just for the money. It ain’t just about the money. It’s really not. It’s about doing whatever it takes for you to have your voice heard. So I don’t know what you’re writing in that book you always carrying around, but it better be classic because you ain’t gonna get no two times to get it right, you hear me?

After high school, he’d passed two relatively laid-back years as a student at Occidental College in Los Angeles before transferring to Columbia, where by his own account he’d behaved nothing like a college boy set loose in 1980s Manhattan and instead lived like a sixteenth-century mountain hermit, reading lofty works of literature and philosophy in a grimy apartment on 109th Street, writing bad poetry, and fasting on Sundays. We laughed about all of it, swapping stories about our backgrounds and what led us to the law. Barack was serious without being self-serious. He was breezy in his manner but powerful in his mind. It was a strange, stirring combination. Surprising to me, too, was how well he knew Chicago. Barack was the first person I’d met at Sidley who had spent time in the barbershops, barbecue joints, and Bible-thumping black parishes of the Far South Side. Before going to law school, he’d worked in Chicago for three years as a community organizer, earning $12,000 a year from a nonprofit that bound together a coalition of churches. His task was to help rebuild neighborhoods and bring back jobs. As he described it, it had been two parts frustration to one part reward: He’d spend weeks planning a community meeting, only to have a dozen people show up. His efforts were scoffed at by union leaders and picked apart by black folks and white folks alike. Yet over time, he’d won a few incremental victories, and this seemed to encourage him. He was in law school, he explained, because grassroots organizing had shown him that meaningful societal change required not just the work of the people on the ground but stronger policies and governmental action as well. Despite my resistance to the hype that had preceded him, I found myself admiring Barack for both his self-assuredness and his earnest demeanor. He was refreshing, unconventional, and weirdly elegant.

I am going to end up alone," he moaned. "Not in any conceivable universe!" One of Sadie's best qualities is the ability to say "Are you effing insane?" with such sweet conviction and nicer words. "I am going to end up alone in a one-room apartment over a dry cleaner." "A dry cleaner?" "He could have said a bar," I offered. "True," he conceded. Frankie was on a roll. "I am going to end up alone in a one-room apartment over a dry cleaner with a cat. Who bites me." "Oh,Frankie-" "I am going to end up alone in a one-room apartment over a dry cleaner with a cat who bites me and pees in my closet full of moth-eaten sweaters." "Well,maybe," Sadie said, reaching around to hug both of us. "But the sweaters will be Dolce & Gabbana." One of her other fabulous qualities is that underneath the sweet conviction, she does have a sense of humor. Frankie did laugh. Then he gave a sigh that I could feel all the way through me. I knew Sadie did,too. "I liked him," he said, very quietly. "I really did. And I thought he felt the same way. I bent and twisted and distorted everything that happened between us to fit my pretty little picture. God, I believed my own hype. How stupid, how incredibly stupid was that?" "Not stupid." Sadie squeezed. "Hopeful. And if we're not that, what's the point? El? Help me out here." I wanted to.I really did. But all I could think of was the fact that at home, exactly where I'd put it in my bag, which was still exactly where I'd dumped it on the floor, was the evidence that Edward had let me down. I was keeping that to myself, at least for the moment. Twisted it to fit my pretty little picture. I didn't think I could take Frankie's complete lack of surprise that a guy (even a dead one) had let me down-or Sadie's sympathy. Not on top of my own anger. Because,plain and simple,it wasn't okay to look at another woman like that, not when you met the love of your life and gave a big flipped finger to the people around you so you could be with her. Not okay even if she was dead, because I, Ella, really really want to believe that sometimes love does conquer all, and sometimes some things do last foever. Truth: Yes,I really am that naive. "You're perfect," I said to Frankie. And I meant it.

With the news that he would soon be a daddy again, Steve seemed inspired to work even harder. Our zoo continued to get busier, and we had trouble coping with the large numbers. The biggest draw was the crocodiles. Crowds poured in for the croc shows, filling up all the grandstands. The place was packed. Steve came up with a monumental plan. He was a big fan of the Colosseum-type arenas of the Roman gladiator days. He sketched out his idea for me on a piece of paper. “Have a go at this, it’s a coliseum,” he declared, his eyes wide with excitement. He drew an oval, then a series of smaller ovals in back of it. “Then we have crocodile ponds where the crocs could live. Every day a different croc could come out for the show and swim through a canal system”--he sketched rapidly--“then come out in the main area.” “Canals,” I said. “Could you get them to come in on cue?” “Piece of cake!” he said. “And get this! We call it…the Crocoseum!” His enthusiasm was contagious. Never mind that nothing like this had ever been done before. Steve was determined to take the excitement and hype of the ancient Roman gladiators and combine it with the need to show people just how awesome crocs really were. But it was a huge project. There was nothing to compare it to, because nothing even remotely similar had ever been attempted anywhere in the world. I priced it out: The budget to build the arena would have to be somewhere north of eight million dollars, a huge expense. Wes, John, Frank, and I all knew we’d have to rely on Steve’s knowledge of crocodiles to make this work. Steve’s enthusiasm never waned. He was determined. This would become the biggest structure at the zoo. The arena would seat five thousand and have space beneath it for museums, shops, and a food court. The center of the arena would have land areas large enough for people to work around crocodiles safely and water areas large enough for crocs to be able to access them easily. “How is this going to work, Steve?” I asked, after soberly assessing the cost. What if we laid out more than eight million dollars and the crocodiles decided not to cooperate? “How are you going to convince a crocodile to come out exactly at showtime, try to kill and eat the keeper, and then go back home again?” I bit my tongue when I realized what was coming out of my mouth: advice on crocodiles directed at the world’s expert on croc behavior. Steve was right with his philosophy: Build it, and they will come. These were heady times. As the Crocoseum rose into the sky, my tummy got bigger and bigger with our new baby. It felt like I was expanding as rapidly as the new project. The Crocoseum debuted during an Animal Planet live feed, its premiere beamed all over the world. The design was a smashing success. Once again, Steve had confounded the doubters.

Android Girl Just Wants to Have a Baby! The first thing I do when I wake up is run my hands over my body. I like to make sure all my wires are in place. I lotion my silicone shell and snap my hair helmet over my head. I once had a dream I was a real girl, but when I woke up I was still myself in my paleness under the halogen light. The saliva of androids emits a spectral resonance, barely sticky between freshly-gapped teeth. After they made me, the first thing they did was peel the cellophane from my eyes. I blinked once, twice, and cried because that's how you say you are alive before you are given language. They named each of my heartbeats on the oceanic monitor: Guanyin, Yama, Nuwa, Fuxi, Chang'e, Zao-Shen. I listened to them blur into one. The fetus carves for itself a hollowed vector, a fragile wetness. In utero, extension cords are umbilical. Before puberty, I did not know there was such a thing as dishonor. Diss-on- her. This is what they said when I began to drip petrol between my legs. A tension exists between ritual and proof, a fantasy and its execution. Since then, I have been to the emergency room twice. The first time for a suicide attempt, and the second time because my earring was swallowed up by my newly pierced earlobe overnight, and when I woke up, it was tangled in a helix of wires. The idea of dying doesn't scare me but the ocean does. I was once told that fish will swim up my orifices if I am no longer a virgin. Is anyone thinking about erotic magazines when they are not aroused, pubes parted harshly down the center like red seas? My body carries the weight of four hundred eggs. I rise from a weird slumber, let them drip into the bath. This is what I'll leave behind - tiny shards purer than me. I have always been afraid of pregnant women because of their power, and because I don't yet understand what it means to carry something stubborn and blossoming inside of me, screeching towards an exit. The ectoplasm is the telos for the wound. A trance state is induced when salt is poured on it, pixel by pixel. I wish they had made me into an octopus instead, because octopuses die after their eggs hatch and crawl out into the sea, and I want to know what it's like to set something free into the dark unknown and trust it to choose mercy. If you can generate aura in a non-place, then there is no such thing as an authentic origin. In Chinese, the word for mercy translates to my heart hurts for you. They say my heart continues beating even after it is dislocated from my body. The sound of its beating comes from the valves opening and closing like a portal - Guanyin, Yama, Nuwa, Fuxi, Chang'e, Zao-Shen. I first learned about love by watching a sex tape where a girl looks up from performing fellatio and says, show them the sunset. Her boyfriend pans the camera to the sky, which is tinged violet like a bruise. In this moment, the sky displaces her, all digital and hyped, and saturates the scene until it collapses on me too, its transient witness. I move in the space between belly ring and catharsis. That night I have a dream where I am a camgirl, but all I do on screen is wash my laundry. Everybody loves me because I am a real girl doing real girl things. What lives on the border between meditation and oblivion, static and flux, a pomegranate seed and an embryo? I set up my webcam in the corner of the room and play ambient music while I scrub my underwear, letting soap bubbles rise up from the sink, laughing when they overflow on the linoleum floor - my frizzy hair, my pockmarked skin, my face slick with sweat. A body with exit wounds. I ride the bright rails of an animal forgetting. And when I wake up, the sky is a mess of blue.

outstretched in greeting and stood there for what felt like several minutes. As she finally turned around to face me, she just looked down at my hand and back up at me and without another word walked out of the room. I quickly threw my bags on the empty bed, which I assumed was mine, and

I believed God could do miracles in theory, and growing up I had seen things that made me long for more. But the truth was, I was thoroughly turned off by the hype, manipulation and abuse that I had seen in many ministry settings. I knew I wanted to follow God, but I had come to a place of simply hanging in there, resigning myself to a Christian life based primarily on trudging it out and not expecting too much. One of the highest values in the Kingdom of God is faithfulness, but what good is faithfulness without faith?

Ego" I've been watching you as of lately Walking around like you're something to talk about Like you bought into your own hype I've been watching you as of lately Walking around like you're something to talk about Like you bought into your own hype It used to be just you and me baby Running around like we had it all figured out There's nothing left beyond those lies Liiii-ie you're living such a liiii-ie! I wanna hold you but you're untouchable You're too caught up in your ego I wanna love you but you're making it impossible Wanna believe you, but you're so far gone Did you forget where you came from? I wanna love you but you're making it impossible When did you decided to get shady I wanna know the moment you changed to someone new I hate that you become that type Hoping all the moments of maybe Thinking about it, there's nothing to figure out I see you gave in without a fight! Liiii-ie you're living such a liiii-ie! I wanna hold you but you're untouchable You're too caught up in your ego I wanna love you but you're making it impossible Wanna believe you, but you're so far gone Did you forget where you came from? I wanna love you but you're making it impossible I wanna hold you but you're untouchable You're too caught up in your ego I wanna love you but you're making it impossible Wanna believe you, but you're so far gone Did you forget where you came from? I wanna love you but you're making it impossible I wanna hold you but you're untouchable You're too caught up in your ego I wanna love you but you're making it impossible Wanna believe you, but you're so far gone Did you forget where you came from? I wanna love you but you're making it impossible

I’m Captain Florida, the state history pimp Gatherin’ more data than a DEA blimp West Palm, Tampa Bay, Miami-Dade Cruisin’ the coasts till Johnny Vegas gets laid Developer ho’s, and the politician bitches Smackin’ ’em down, while I’m takin’ lots of pictures Hurricanes, sinkholes, natural disaster ’Scuse me while I kick back, with my View-Master (S:) I’m Captain Florida, obscure facts are all legit (C:) I’m Coleman, the sidekick, with a big bong hit (S:) I’m Captain Florida, staying literate (C:) Coleman sees a book and says, “Fuck that shit” Ain’t never been caught, slippin’ nooses down the Keys Got more buoyancy than Elián González Knockin’ off the parasites, and takin’ all their moola Recruiting my apostles for the Church of Don Shula I’m an old-school gangster with a psycho ex-wife Molly Packin’ Glocks, a shotgun and my 7-Eleven coffee Trippin’ the theme parks, the malls, the time-shares Bustin’ my rhymes through all the red-tide scares (S:) I’m the surge in the storms, don’t believe the hype (C:) I’m his stoned number two, where’d I put my hash pipe? (S:) Florida, no appointments and a tank of gas (C:) Tequila, no employment and a bag of grass Think you’ve seen it all? I beg to differ Mosquitoes like bats and a peg-leg stripper The scammers, the schemers, the real estate liars Birthday-party clowns in a meth-lab fire But dig us, don’t diss us, pay a visit, don’t be late And statistics always lie, so ignore the murder rate Beaches, palm trees and golfing is our curse Our residents won’t bite, but a few will shoot first Everglades, orange groves, alligators, Buffett Scarface, Hemingway, an Andrew Jackson to suck it Solarcaine, Rogaine, eight balls of cocaine See the hall of fame for the criminally insane Artifacts, folklore, roadside attractions Crackers, Haitians, Cuban-exile factions The early-bird specials, drivin’ like molasses Condo-meeting fistfights in cataract glasses (S:) I’m the native tourist, with the rants that can’t be beat (C:) Serge, I think I put my shoes on the wrong feet (S:) A stack of old postcards in another dingy room (C:) A cold Bud forty and a magic mushroom Can’t stop, turnpike, keep ridin’ like the wind Gotta make a detour for a souvenir pin But if you like to litter, you’re just liable to get hurt Do ya like the MAC-10 under my tropical shirt? I just keep meeting jerks, I’m a human land-filler But it’s totally unfair, this term “serial killer” The police never rest, always breakin’ in my pad But sunshine is my bling, and I’m hangin’ like a chad (S:) Serge has got to roll and drop the mike on this rap . . . (C:) Coleman’s climbin’ in the tub, to take a little nap . . . (S:) . . . Disappearin’ in the swamp—and goin’ tangent, tangent, tangent . . . (C:) He’s goin’ tangent, tangent . . . (Fade-out) (S:) I’m goin’ tangent, tangent . . . (C:) Fuck goin’ platinum, he’s goin’ tangent, tangent . . . (S:) . . . Wikipedia all up and down your ass . . . (C:) Wikity-Wikity-Wikity . . .

Aside from the movies, examples of positive-Black Swan businesses are: some segments of publishing, scientific research, and venture capital. In these businesses, you lose small to make big. You have little to lose per book and, for completely unexpected reasons, any given book might take off. The downside is small and easily controlled. The problem with publishers, of course, is that they regularly pay up for books, thus making their upside rather limited and their downside monstrous. (If you pay $10 million for a book, your Black Swan is it not being a bestseller.) Likewise, while technology can carry a great payoff, paying for the hyped-up story, as people did with the dot-com bubble, can make any upside limited and any downside huge. It is the venture capitalist who invested in a speculative company and sold his stake to unimaginative investors who is the beneficiary of the Black Swan, not the "me, too" investors.

Scandals have often plagued candidates, but the Clintons exceeded any politician’s call of duty. Mrs. Clinton coined her “vast right-wing conspiracy” phrase a few years later, but back in November 1992 I chalked up the hype that surrounded them as just that—hype. As the Clinton scandals accumulated, however, in the months and years to come, I kept recalling being on detail at a Clinton campaign event, small-talking with an Arkansas sheriff. When I asked about the Clintons’ latest rumors, he gave me a thousand-yard stare. “Let me tell you something, Gary. Everything—everything they say about them is true. The Clintons are ruthless. And [the media] don’t even know the half of it.” I didn’t know what to make of that. “From what I’ve seen,” he continued, “there’s no doubt in my mind they will secure the presidency—you watch.” “How can you be so sure,” I asked, “especially with all the scandals, the allegations of affairs, bribery.…” He just waved me off, saying, “It will never matter. Officer, I’m telling you they can spin shit into gold.” He spoke with great conviction, looking me straight in the eye, as if knowing that what he said was stranger than fiction. He spoke from a profound well of personal experiences with the Clintons, and it was eerie.

Queen always seemed to me to be manufactured championship music—designed to be played in stadiums to get fans hyped up about paying money to watch other men play a child’s game. With songs like We Will Rock You and We Are The Champions, they were the pep rally of pop rock.

I spent so long in the bathroom hyping myself up with one of JJ’s silly pep talks to convince myself to ask her if she wanted to go on a date when I get home from camp that if she’d rejected me to my face, I’d have probably locked myself back in the bathroom.

I didn’t want you to leave. What are you talking about?” “You were in the bathroom for so long. You were waiting for me to go, I heard you talking to someone so I left.” “I was talking to myself, Rory. I was hyping myself up to ask you out, which is something I hoped to never have to admit out loud to you. But I’d rather embarrass myself than have you think I’m the type of guy who would wait in a bathroom for you to leave.” “Oh my God.” “I never do the one-night stand thing and I thought we had fun. I wanted to see you again, but you’re so out of my league and—” “Oh my God.

For me feeling cute was less about attracting somebody to sleep with and more about hyping myself up to get shit done. No one could tell me anything when I put on clothes that were made specifically for my body.

Wrap up Bingo "Grageas de sabores" *Vomito: "Un beso imborrable" 5/5 La trama del libro toca temas sensibles de abuso infantil, despierta sentimientos fuertes. *Suciedad: "Voz" 3/5 No me gusto el libro, el maltrato que sufrieron las mujeres, daban ganas de matar a todos los hombres. *Césped: "Bajo las estrellas" 3/5 No me gustaron los protagonistas, fueron muy idiotas, seguirían sin hablarse, si no lo hubieran engañados para ir de campamento. *Jabón: "Comandante" 5/5 Matt Hamilton, es absolutamente perfecto, dulce, tierno, tiene un comportamiento impecable en todo el libro, amo lo amoroso que es con Charlotte. *Huevo podrido: "La hipótesis del amor", 5/5 Es una historia muy dulce con Adam y Olive, merece todo el hype que tuvo. *Moco: "Corazón sin valor", 5/5 El sufrimiento que pasaron Alex y Sam, te hace lagrimear en varias partes. *Cerilla: "Sol de invierno" 5/5 Por momentos odie a J.C., Colie, me pareció muy tonta al principio, al final me gustaron ambos personajes. La autora Diana Palmer, nació en el año 1946, *Sandia: "Sucedió un verano" 5/5 Es una linda historia de amor y superación con Piper y Brandon, son perfectos el uno para el otro. *Limón: "Una luna sin miel" 5/5 Me reí mucho con Olive y Ethan, todo lo que pasaron en su luna de miel, mas mala suerte no podían tener

Vienna had this charm to her. She was so confident, and she could make you believe whatever you wanted. She seemed like a natural born leader who was charismatic. With her hyping me up, I felt like I could do anything.

What is Happiness? Happiness is a myth. It doesn't exist. What we call happiness is merely a temporary sensation of excitement that we receive upon the fulfillment of our expectations. It's not happiness, it's addiction. And since we have made a society out of this insane pursuit of addiction, our brain is never at a healthy state to actually fathom and more importantly produce true happiness. And what is true happiness? Contentment. You've been working for hours. You haven't had the time to even have some water. Finally you finish your work and drink a glass of water. The sheer feeling of joy that you receive at that moment - that's happiness, that's contentment. You haven't been near your loved ones for days, for you've been away for work. Finally you get home and take them in your arms - that's happiness, that's contentment. Now let me tell you what is not happiness, what is in fact an unhealthy addiction which only ruins a person's life both mentally and physically. You've been using the same smartphone for over a year now. Suddenly the brand announces the release of a new model. And you get all hyped up to buy that model, despite the fact that you don't really need it. That's addiction - that's an illness. You visit a new place on vacation. But instead of experiencing that place with your heart, you bring your phone out and waste the entire vacation on taking pictures to post on social media. That's addiction, that's illness. You know why? Because when you get home, you realize, you have plenty of pictures of the vacation on your phone alright, but you have no meaningful memory of that place in your heart. In usual circumstances, our brain doesn't distinguish between addiction and true joy. It can only do that, when we stop running and start living. Because at the end of the day, joy is not about fulfilling expectations, joy is about learning to live beyond expectations.

Getting a good look at him… he was huge. Like literally massive. Was that normal? Was he on steroids? “Hey, friend,” I said. “Wait here a second, okay? We’ll get you some help.” He didn’t respond, obviously. Why my heart started beating faster though, I really didn’t get. Never mind, I guess I did. I was going to have to grab this big son of a bitch. If my memory served me correctly—from all the episodes I’d seen of zoo shows and the one game warden show—you just kind of had to... grab them. Could they smell fear? Like dogs? I eyed my new friend and hoped like hell he couldn’t. Two seconds later, the door to the house burst open and Amos was out, setting a big crate down on the deck before running back inside. He was back out another second later, shoving something into his pockets and then picking up the crate again. He slowed down as he got closer to the garage and walked way around where the bird was still standing. He was breathing hard as he slowly set it down between us, then pulled out some leather gloves from his pockets and handed those over too. “This is the best I could find,” he said, eyes wide and face flushed. “You sure about this?” I slipped the gloves on and let out a shaky exhale before giving him a nervous smile. “No.” I kind of laughed from the nerves. “If I die—” That got him to roll his eyes. “You’re not doing to die.” “Make up some story about how I saved your life, okay?” He looked at me. “Maybe we should wait for my dad.” “Should we? Yeah, but are we? No, we have to get him. He should have flown off by now, and we both know it.” Amos cursed again under his breath, and I gulped. Might as well get it over with. Five minutes from now wasn’t going to change anything. My mom would’ve done it. “Okay, I can do this,” I tried to hype myself up. “Just like a chicken, right?” “You’ve picked up a chicken before?” I eyed Am. “No, but I’ve seen my friend do it. It can’t be that hard.” I hoped. I could do this. Just like a chicken. Just like a chicken. Opening and closing my hands with the big gloves on, I bounced my shoulders and moved my neck from side to side. “Okay.” I inched closer to the bird, willing my heart to slow down. Please don’t let him smell fear. Please don’t let him smell fear. “All right, love, pal, pretty boy. Be nice, okay? Be nice. Please be nice. You’re beautiful. I love you. I just want to take care of you. Please be nice—” I swooped down. Then I shouted, “Ahh! I got him! Open the crate! Open the crate! Am, open it! Shit, he’s heavy!” Out of the corner of my eye, Amos rushed over with the crate, door open, and set it on the ground. “Hurry, Ora!” I held my breath as I waddled, holding what I was pretty sure was a steroid-taking bird—who wasn’t struggling at all, honestly—and as fast as possible, set him inside, facing away from me, and Amos slammed it shut just as I got my arms out of there without getting murdered. We both jumped back and then peeked through the metal gate. He was just hanging out in there. He was fine. At least I was pretty sure he was; it wasn’t like he was making faces. I held up my hand, and Am high-fived it. “We did it!” The teenager grinned. “I’ll call Dad.” We high-fived again, pumped up. Amos hustled back inside his house, and I crouched down to look at my friend once more. He was a good hawk. “Good job, pretty boy,” I praised him. Most of all though, I’d done it! I got him in there! All by myself. How about that?

CAR-T therapy in a very small subset of cancer patients with lymphoid disease is fantastically successful, albeit causing severe short-term toxicities and many known and unknown lifelong side effects. It is clear that much work lies ahead before this strategy can be scaled up for general use. Yet the hype surrounding CAR-T is such that practically every patient questions me about why they are being deprived of the magic cure. The results are not always magical: Despite high-target, cell-specific killing in vitro and encouraging preclinical efficacies in murine tumor models, clinical responses of adoptively transferred T cells expressing α-folate receptor (FR) specific CAR in ovarian cancer were disappointing. No reduction of tumor burden was seen in the 14 patients studied. The absence of efficacy was ascribed to lack of specific trafficking of the T cells to tumor and short persistence of the transferred T cells.

Watch your words. If the phrases you use for baby and dog are too similar, your pup may get hyped up at the wrong time or be utterly confused. ("Why are you looking at the newbie instead of me!") Change phrases like “What a good girl!” to “What a great puppy!