Hormone Best Quotes

I don’t know why we take our worst moods so much more seriously than our best, crediting depression with more clarity than euphoria. We dismiss peak moments and passionate love affairs as an ephemeral chemical buzz, just endorphins or hormones, but accept those 3 A.M. bouts of despair as unsentimental insights into the truth about our lives.

So you love me," said Petra softly when the kiss ended. I'm a raging mass of hormones thet I'm too young to understand," said Bean. "You're a female of a closely related species. According to all the best primatologists, I really have no choice." That's nice," she said...

Oxytocin, the luv hormone, makes us more prosocial to Us and worse to everyone else. That’s not generic prosociality. That’s ethnocentrism and xenophobia. In other words, the actions of these neuropeptides depend dramatically on context—who you are, your environment, and who that person is.

If hitting an unexpected speed bump with your car equates to the best sex you've had lately, you know your hormones are sending you a signal.

I don't know why we take our worst moods so much more seriously than our best, crediting depression with more clarity than euphoria. We dismiss peak moments and passionate love affairs as an ephemeral chemical buzz, just endorphins or hormones, but accept those 3 a.m. bouts of despair as unsentimental insights into the truth about our lives.

Testosterone also increases confidence and optimism, while decreasing fear and anxiety.5 This explains the “winner” effect in lab animals, where winning a fight increases an animal’s willingness to participate in, and its success in, another such interaction. Part of the increased success probably reflects the fact that winning stimulates testosterone secretion, which increases glucose delivery and metabolism in the animal’s muscles and makes his pheromones smell scarier. Moreover, winning increases the number of testosterone receptors in the bed nucleus of the stria terminalis (the way station through which the amygdala communicates with the rest of the brain), increasing its sensitivity to the hormone. Success in everything from athletics to chess to the stock

The most common theory points to the fact that men are stronger than women and that they have used their greater physical power to force women into submission. A more subtle version of this claim argues that their strength allows men to monopolize tasks that demand hard manual labor, such as plowing and harvesting. This gives them control of food production, which in turn translates into political clout. There are two problems with this emphasis on muscle power. First, the statement that men are stronger is true only on average and only with regard to certain types of strength. Women are generally more resistant to hunger, disease, and fatigue than men. There are also many women who can run faster and lift heavier weights than many men. Furthermore, and most problematically for this theory, women have, throughout history, mainly been excluded from jobs that required little physical effort, such as the priesthood, law, and politics, while engaging in hard manual labor in the fields....and in the household. If social power were divided in direct relation to physical strength or stamina, women should have got far more of it. Even more importantly, there simply is no direct relation between physical strength and social power among humans. People in their sixties usually exercise power over people in their twenties, even though twenty-somethings are much stronger than their elders. ...Boxing matches were not used to select Egyptian pharaohs or Catholic popes. In forager societies, political dominance generally resides with the person possessing the best social skills rather than the most developed musculature. In fact, human history shows that there is often an inverse relation between physical prowess and social power. In most societies, it’s the lower classes who do the manual labor. Another theory explains that masculine dominance results not from strength but from aggression. Millions of years of evolution have made men far more violent than women. Women can match men as far as hatred, greed, and abuse are concern, but when push comes to shove…men are more willing to engage in raw physical violence. This is why, throughout history, warfare has been a masculine prerogative. In times of war, men’s control of the armed forces has made them the masters of civilian society too. They then use their control of civilian society to fight more and more wars. …Recent studies of the hormonal and cognitive systems of men and women strengthen the assumption that men indeed have more aggressive and violent tendencies and are…on average, better suited to serve as common soldiers. Yet, granted that the common soldiers are all men, does it follow that the ones managing the war and enjoying its fruits must also be men? That makes no sense. It’s like assuming that because all the slaves cultivating cotton fields are all Black, plantation owners will be Black as well. Just as an all-Black workforce might be controlled by an all-White management, why couldn’t an all-male soldiery be controlled by an all-female government?

Testosterone has far less to do with aggression than most assume. Within the normal range, individual differences in testosterone levels don’t predict who will be aggressive. Moreover, the more an organism has been aggressive, the less testosterone is needed for further aggression. When testosterone does play a role, it’s facilitatory—testosterone does not 'invent' aggression. It makes us more sensitive to triggers of aggression. Also, rising testosterone levels foster aggression only during challenges to status. Finally, crucially, the rise in testosterone during a status challenge does not necessarily increase aggression; it increases whatever is needed to maintain status. In a world in which status is awarded for the best of our behaviors, testosterone would be the most prosocial hormone in existence.

Teens had the world's best built-in poker face: a hormone-fueled, constant glare of bored contempt.

What's amazing to me now is that I actually recall fixating on the fact that my thighs a-l-m-o-s-t touched at the top....If I could go back in time and slap my eighteen-year-old self, I would. I would tell her to snap out of it, because that's the best you thighs will ever be. You should take pictures of your thighs right now so you can remember how amazing they were!

Obviously, oxytocin and vasopressin are the grooviest hormones in the universe. Pour them into the water supply, and people will be more charitable, trusting, and empathic. We'd be better parents and would make love, not war (mostly platonic love, though, since people in relationships would give wide berths to everyone else). Best of all, we'd buy all sorts of useless crap, trusting the promotional banners in stores once oxytocin starts spraying out of the ventilation system.

Emergencies send sparks to the darkest corner of us. They wake up our hormones and neurotransmitters, they remove the rust from our body and mind, and they show us we can still handle crisis with poise. Emergencies push us to our limits. At those limits, the best inside us comes out. The eyes of our mind open, exceptional vision occurs to us, and we have a chance to become extraordinary.

Blame your body. The whole biological purpose of existence is to mate, so from the time we hit puberty, our hormones are demanding us to couple up. Maybe it’s basic instinct to feel inadequate if you’re single." "That’s what sucks. There’s so many more interesting things than guys, but guys are what we spend most of our time talking about." "I think that’s just the way it is, though. No matter what we do, it’s always more special if there’s a boyfriend to share it with." "Or a best friend.

It seems to me that if God felt it best to delay marriage into the latter part of your twenties, He would also see fit to delay the hormonal urge to want to have sex. Or perhaps it was never His intent to delay marriage in an effort to "become more independent," "enjoy singlehood," and "build our careers.

The biology of emotional freedom depends on getting your endorphins flowing and turning off your stress hormones. How you achieve this? Laughter, exercise, meditation and doing anything that makes you loved.

Vanessa was deprived of her hormones in prison and thus retained several male characteristics that would have been less evident otherwise, most notably her voice. While she spoke in a high, little-girl voice most of the time, she could switch at will to a booming, masculine Richard-voice. She loved to sneak up behind people and scare the crap out of them this way, and she was very effective at quieting a noisy dining hall, roaring, "Y'all hush up!" Best of all were her Richardian encouragements on the softball field, where she was a sought-after teammate. That bitch could hit.

The artificial intelligence pioneer Marvin Minsky once defined free will as “internal forces I do not understand.”26 People intuitively believe in free will, not just because we have this terrible human need for agency but also because most people know next to nothing about those internal forces. And even the neuroscientist on the witness stand can’t accurately predict which individual with extensive frontal damage will become the serial murderer, because science as a whole still knows about only a handful of those internal forces. Shattered bone → inflammation → constricted movement is easy. Neurotransmitters + hormones + childhood + ____ + ____ + isn’t.

In the absence of stress, men tend toward more risk taking than women; thus, once again, hormones enhance a preexisting tendency.

When a rat wins a fight, the number of testosterone receptors increases in the ventral tegmentum and accumbens, increasing sensitivity to the hormone’s feel-good effects.10

Most days I get hyped up to be the best version of myself as I can be, while I battle my array of multiple personalities and emotions like a badass warrior playing tennis.

the brain is most effective at learning new material when stress hormones are slightly elevated by a novel experience, a theory verified by modern brain imaging. Therefore, the best way to rethink something we’ve been doing for years—the way we do our jobs, the way we interact with others, the way we see the world—is to step outside of ourselves, and outside of our comfort zone.

Twelve chapters later, I’ve learned how our brains control many aspects of our physiology, including the tools that the body has available—from hormones and natural painkillers to the weapons of the immune system—to ease symptoms and fight disease. Instead of responding purely to physical circumstances, I’ve seen how the brain uses our perception of our environment, including memories of the past and predictions about the future, to decide how best to allocate its resources. These processes can have an effect within seconds, or they can influence our physiology for years to come.

Oxytocin, the luv hormone, makes us more prosocial to Us and worse to everyone else. That’s not generic prosociality. That’s ethnocentrism and xenophobia. In other words, the actions of these neuropeptides depend dramatically on context—who you are, your environment, and who that person is. As we will see in chapter 8, the same applies to the regulation of genes relevant to these neuropeptides.

There’s support for the idea—three of my favorites are that (a) forcing depressed people to smile makes them feel better; (b) instructing people to take on a more “dominant” posture makes them feel more so (lowers stress hormone levels); and (c) muscle relaxants decrease anxiety (“Things are still awful, but if my muscles are so relaxed that I’m dribbling out of this chair, things must be improving”). Nonetheless,

even while it’s true that we are tied to our molecules and proteins and neurons—as strokes and hormones and drugs and microorganisms indisputably tell us—it does not logically follow that humans are best described only as pieces and parts.

She’d wanted Randall Parks from the moment her hormones kicked in. Her best friend, her guardian when things got rough, her knight in somewhat-rusted and dinged up armor—he wore many hats in her life and none more important than that of best friend.

There’s support for the idea—three of my favorites are that (a) forcing depressed people to smile makes them feel better; (b) instructing people to take on a more “dominant” posture makes them feel more so (lowers stress hormone levels); and (c) muscle relaxants decrease

there is a hidden intelligence embedded in the female fertility cycle: an ancient knowledge that women can use to make the best decisions in their modern lives. Behind the everyday behavior that some interpret as simply “hormonal,” there is a biochemical process that has helped females—billions across thousands of species—choose mates, avoid rape, compete with female rivals, fight for resources, and produce offspring with fit genes and good prospects. To master these challenges, female brains evolved to conspire with their hormones rather than be corrupted by them.

There are not different disciplinary buckets. Instead, each one is the end product of all the biological influences that came before it and will influence all the factors that follow it. Thus, it is impossible to conclude that a behavior is caused by a gene, a hormone, a childhood trauma, because the second you invoke one type of explanation, you are de facto invoking them all. No buckets. A “neurobiological” or “genetic” or “developmental” explanation for a behavior is just shorthand, an expository convenience for temporarily approaching the whole multifactorial arc from a particular perspective.

it’s human behavior, human social behavior, and in many cases abnormal human social behavior. And it is indeed a mess, a subject involving brain chemistry, hormones, sensory cues, prenatal environment, early experience, genes, both biological and cultural evolution, and ecological pressures, among other things.

Over the course of minutes to hours, hormonal effects are predominantly contingent and facilitative. Hormones don’t determine, command, cause, or invent behaviors. Instead they make us more sensitive to the social triggers of emotionally laden behaviors and exaggerate our preexisting tendencies in those domains.

Our best minds are not wasting their time trying to give meaning to death. Instead, they are busy investigating the physiological, hormonal and genetic systems responsible for disease and old age. They are developing new medicines, revolutionary treatments and artificial organs that will lengthen our lives and might one day vanquish the Grim Reaper himself.

Healing Foods When you’re looking to boost the immune system and support the reproductive system, the best foods to concentrate on are wild blueberries, sesame tahini, avocados, black beans, asparagus, apples, spinach, black grapes, and cucumbers. They’ll help by variously providing antioxidants, preventing hot flashes, providing critical nutrients to fortify vital organs, reducing inflammation, and keeping hormone levels balanced. Herbs and Supplements to Address General Symptoms Silver hydrosol: kills viruses, bacteria, and other microbes on contact and supports the immune system. Zinc: kills viruses, boosts the immune system, and helps protect the endocrine system. Licorice root: aids the adrenal glands and helps balance the body’s levels of cortisol and cortisone. L-lysine: impairs the ability of virus cells to move and reproduce. Vitamin B12 (as methylcobalamin and/or adenosylcobalamin): strengthens the central nervous system. Nascent iodine: stabilizes and strengthens the thyroid and the rest of the endocrine system. Ashwagandha: fortifies the adrenal glands and helps balance the production of cortisol.

Avoid Menstruating If, you are using hormonal contraception, such as a low-dose birth control pill, you can avoid the whole change in pH caused by menstrual blood by avoiding menstruation. That’s right! Take your pill straight through the placebo days and skip having your period. And yes, this is safe. As discussed in chapter 9, skipping menstruation is a common treatment for endometriosis.

Hormonal responses to various fetal and childhood experiences have epigenetic effects on genes related to the growth factor BDNF, to the vasopressin and oxytocin system, and to estrogen sensitivity. These effects are pertinent to adult cognition, personality, emotionality, and psychiatric health. Childhood abuse, for example, causes epigenetic changes in hundreds of genes in the human hippocampus.

Remarkably, the size of neurons’ dendritic trees in the hippocampus expands and contracts like an accordion throughout a female rat’s ovulatory cycle, with the size (and her cognitive skills) peaking when estrogen peaks.fn6 Thus, neurons can form new dendritic branches and spines, increasing the size of their dendritic tree or, in other circumstances, do the opposite; hormones frequently mediate these effects.

Oxytocin and vasopressin facilitate mother-infant bond formation and monogamous pair-bonding, decrease anxiety and stress, enhance trust and social affiliation, and make people more cooperative and generous. But this comes with a huge caveat—these hormones increase prosociality only toward an Us. When dealing with Thems, they make us more ethnocentric and xenophobic. Oxytocin is not a universal luv hormone. It’s a parochial one.

Hero Intercedes”: His hands flickered upward, and before I knew it, they were cupping my face. So, damnably fast now. Demonic-like fast. Trent reeled me closer. Our foreheads joined. He held me, while I trembled in his arms. I was vaguely aware of Evans and Maxwell watching, although it didn’t seem important. Nothing seemed important whenever he did this. It felt like we were enclosed in our own personal bubble made only for the two of us. Trent murmured something in my ear. We stood like that until my shaky legs gradually regained strength. I shut my eyes and pretended my body wasn’t sizzling with heat-lightning because Trent stood so close. My hormones always decided to rebel whenever he put his arms around me. And it wasn’t totally awkward and uncomfortable. No, it felt like the best thing I’d experienced since before Dad’s death. And that’s saying a lot.

Two complications illustrate some endocrine principles.fn16 Estrogen contributes to maternal aggression. But estrogen can also reduce aggression and enhance empathy and emotional recognition. It turns out there are two different types of receptors for estrogen in the brain, mediating these opposing effects and with their levels independently regulated. Thus, same hormone, same levels, different outcome if the brain is set up to respond differently.51

Genes have plenty to do with behavior. Even more appropriately, all behavioral traits are affected to some degree by genetic variability.65 They have to be, given that they specify the structure of all the proteins pertinent to every neurotransmitter, hormone, receptor, etc. that there is. And they have plenty to do with individual differences in behavior, given the large percentage of genes that are polymorphic, coming in different flavors. But their effects are supremely context dependent.

The situation with regard to insulin is particularly clear. In many parts of the world diabetic children still die from lack of this hormone. ... [T]hose of us who search for new biological facts and for new and better therapeutic weapons should appreciate that one of the central problems of the world is the more equitable distribution and use of the medical and nutritional advances which have already been established. The observations which I have recently made in parts of Africa and South America have brought this fact very forcible to my attention.

Few chemicals confer maleness, but many take it away. Which, if any, are responsible for our own troubles is hard to say. The Pill changed men's lives in more ways than one. It caused reproductive hormones to leak into tap water and has been blamed both for the sex changes in freshwater fish and for the drop in our own sperm count. The jury is still out on the issue, but other hormones have had a disastrous effect. A drug called diethylstilbestrol was once thought - in error - to prevent miscarriage. Five million mothers took it and for a time it was even used as a chicken food supplement. A third of the boys exposed to the drug in the womb suffer from small testes or a reduced penis. In rats, the chemical causes prostate and testicular cancer (although there is as yet no sign of those problems in ourselves). To give a powerful steroid to pregnant women was at best unwise, but the effects of other chemicals were harder to foresee. The 1950s saw a wonderful new chemical treatment for banana pests. Soon the substance was much used. Twenty years later the workers noticed something odd: they had almost no children. Their sperm count had dropped by five hundred times.

What’s the replacement? A behavior has just occurred. Why did it happen? Your first category of explanation is going to be a neurobiological one. What went on in that person’s brain a second before the behavior happened? Now pull out to a slightly larger field of vision, your next category of explanation, a little earlier in time. What sight, sound, or smell in the previous seconds to minutes triggered the nervous system to produce that behavior? On to the next explanatory category. What hormones acted hours to days earlier to change how responsive that individual was to the sensory stimuli that trigger the nervous system to produce the behavior? And

respiratory system encompasses the nose, throat, and lungs. Some of the oils that help the respiratory system include eucalyptus, myrrh, fennel, sandalwood, thyme, cypress, bergamot, and sage. · The digestive system is responsible for breaking down food and includes the stomach, liver, intestines, and gallbladder. Oils used for this include dandelion, marshmallow, meadow sweet, and chamomile. · The circulatory system is responsible for transporting blood and oxygen throughout the body. Oils used for this include lemon, lavender, peppermint, fennel, thyme, juniper, and white birch.  · The endocrine system includes the thyroid glands, the pancreas, and the hormone glands. Essential oils used are sweet marjoram, clary sage, fennel, jasmine, rose, lemon, and juniper. · The immune system is responsible for fighting against diseases including everything from a cold to malaria.   ·  The nervous system transmits nerve impulses throughout the body. These cells are vitally important to the function of the human body. Oils used for the nervous system include clove, basil, ylang ylang, lavender, chamomile, bergamot, and sweet marjoram. · The brain is responsible for the functions of almost every organ system throughout the body. The essential oils used for the brain include lavender, chamomile, basil, lemon, peppermint, and ginger.

formulas as easy as possible, I’ve simplified my recommendation to just five core probiotic species that are widely available: Lactobacillus plantarum, Lactobacillus acidophilus, Lactobacillus brevis, Bifidobacterium lactis, and Bifidobacterium longum. Different strains provide different benefits, but these are the ones that will, as we’ve been discussing since the beginning of the book, best support brain health in these ways: • Fortifying the intestinal lining and reducing gut permeability • Reducing LPS, the inflammatory molecule that can be dangerous if it reaches the bloodstream • Increasing BDNF, the brain’s growth hormone • Sustaining an overall balance to crowd out any

Joseph LeDoux at New York University has shown how the BLA learns fear.fn14,20 Expose a rat to an innate trigger of fear—a shock. When this “unconditioned stimulus” occurs, the central amygdala activates, stress hormones are secreted, the sympathetic nervous system mobilizes, and, as a clear end point, the rat freezes in place—“What was that? What do I do?” Now do some conditioning. Before each shock, expose the rat to a stimulus that normally does not evoke fear, such as a tone. And with repeated coupling of the tone (the conditioned stimulus) with the shock (the unconditioned one), fear conditioning occurs—the sound of the tone alone elicits freezing, stress hormone release, and so on.fn15

The key trait of a Sperm Pirate is that she is not driven by desperation. Escaping poverty or hardship is not her motive. She usually has a good education and access to the same opportunities as the man she tries to trap. However, she understands that it is more efficient to enjoy a lavish lifestyle through the sweat of another’s labour. But the Sperm Pirate is acutely aware that the infatuation of a hormonal man has a brief shelf life. This poor collateral must be cashed in before it expires. A pregnancy is the best way to convert this volatile resource into a stable asset. Babies are reliable insurance policies. They create legal obligations for financial support, even when the sweet milk of passion turns sour.

(IMRT) has an advantage. The newer, high-dose, conformally directed, external-beam techniques for radiation therapy such as IMRT have been in widespread use for less than ten years; IGRT has been around for an even shorter time. However, some reports of long-term success are now emerging. New studies suggest that at ten years, high radiation doses alone can produce PSA control or cure rates in 93 percent of men with low-risk prostate cancer. What about more aggressive prostate cancer? As we discussed in chapter 9, the best treatment regimen for men with intermediate- and high-risk prostate cancer is still a moving target, but it will likely turn out to be a combination of high-dose radiation and short- or long-term hormonal therapy.

Do you have the hots for this boy?” her father asked in all seriousness. “Do we need to have him over for dinner so that I can show him my own gun collection?” “Dad.” “Threatening the police isn’t one of your best ideas, Frank,” her mother offered in Olivia’s defense. “He’s not the police, Katy. He’s some hormone driven boy who wants to sweet-talk our daughter into bed so that he can fire off a few rounds of his own.” “Dad!” Olivia’s face grew hot with humiliation. “I’m just speaking the truth, honey. He’s a man. Don’t think he’s never considered it. You’re a beautiful young woman. All I’m saying is that I’d like to send him a little message before he gets any ideas.” Olivia melted into her seat, covering her face with her hands. “Frank, we’re eating.” “Yeah, and?

an important point, throughout this book, whenever I describe work done by Jane Doe or Joe Smith, I actually mean “work done by Doe and a team of her postdocs, technicians, grad students, and collaborators spread far and wide over the years.” I’ll be referring solely to Doe or Smith for brevity, not to imply that they did all the work on their own—science is utterly a team process. In addition, as long as we’re at it, another point: At endless junctures throughout the book, I’ll be reporting the results of a study, along the lines of, “And when you do whatever to this or that brain region/neurotransmitter/hormone/gene/etc., X happens.” What I mean is that on the average X happens, and at a statistically reliable rate. There is always lots of variability, including individuals in whom nothing happens or even the opposite of X occurs.

The history of HRT use dates back to 1966 and the success of Dr. Robert Wilson’s best-selling book Feminine Forever, which he promoted vigorously. The premise of the book was that it was as natural and necessary for a menopausal woman to replace estrogen as it was for a diabetic to replace insulin. Dr. Wilson preached that doing so would keep a woman young, healthy, and attractive. He went so far as to declare that the lack of eggs and decline of reproductive hormones in a menopausal woman was a “galloping catastrophe”5 that could only be averted by taking estrogen supplements. He explained that with estrogen supplements, “Breasts and genital organs will not shrivel. Such women will be much more pleasant to live with and will not become dull and unattractive.” According to Dr. Wilson’s son, Ronald, all of his father’s expenses to write Feminine Forever were paid for by Wyeth-Ayerst, the maker of the synthetic estrogen supplement Premarin. He also said that Wyeth-Ayerst financed his father’s organization, the Wilson Research Foundation, which had offices on Park Avenue in Manhattan.

IS CARDIO BEST BEFORE OR AFTER LIFTING? NEITHER! Doing cardio right before or after lifting can seriously hinder muscle and strength gains. Why? Researchers from RMIT University worked with well–trained athletes in 2009 and found that “combining resistance exercise and cardio in the same session may disrupt genes for anabolism.” In laymen’s terms, they found that combining endurance and resistance training sends “mixed signals” to the muscles37. Cardio before the resistance training suppressed anabolic hormones such as IGF–1 and MGF, and cardio after resistance training increased muscle tissue breakdown. Several other studies, such as those conducted by Children’s National Medical Center38, the Waikato Institute of Technology39, and the University of Jyvaskyla (Finland)40 , came to same conclusions: training for both endurance and strength simultaneously impairs your gains on both fronts. Training purely for strength or purely for endurance in a workout is far superior. Cardio before weightlifting also saps your energy and makes it much harder to train heavy, which in turn inhibits your muscle growth. So, how do you do it right?

RESISTANCE TRAINING SHOULD HAVE BEEN INVENTED FOR WOMEN. The fitness industry has been plagued with more myths than ancient Greece. One of the most glaring is that women who weight train will look like Mr. Universe. There are still many women who are sidetracked by this common misperception, thereby avoiding weights altogether and bypassing the opportunity to achieve a beautiful, shapely body. One of the biggest differences between men and women is their hormone levels and how these hormones behave—most specifically, testosterone. Testosterone bulks up muscle mass in most men. Men have significantly higher testosterone levels than women, and therefore increasing muscle mass for men is much easier. The vast majority of women cannot build huge, bulging muscles because they have a tiny fraction of the testosterone found in men. There are so many benefits to resistance training for both men and women, but the some of the benefits are very specific to women’s health. For women, the truth is that resistance training increases your metabolism so that you burn fat more easily (and women tend to carry more body fat than men), you build bone mass and prevent osteoporosis (which affects more women than men), and you balance your hormones (which tend to fluctuate wildly in women as they age). Also, women who do resistance training feel a boost in self-esteem and gain renewed physical and mental strength because of their new sexy shape. Resistance training is a woman’s best friend. I rest my case.

Here’s how I’ve always pictured mitigated free will: There’s the brain—neurons, synapses, neurotransmitters, receptors, brainspecific transcription factors, epigenetic effects, gene transpositions during neurogenesis. Aspects of brain function can be influenced by someone’s prenatal environment, genes, and hormones, whether their parents were authoritative or their culture egalitarian, whether they witnessed violence in childhood, when they had breakfast. It’s the whole shebang, all of this book. And then, separate from that, in a concrete bunker tucked away in the brain, sits a little man (or woman, or agendered individual), a homunculus at a control panel. The homunculus is made of a mixture of nanochips, old vacuum tubes, crinkly ancient parchment, stalactites of your mother’s admonishing voice, streaks of brimstone, rivets made out of gumption. In other words, not squishy biological brain yuck. And the homunculus sits there controlling behavior. There are some things outside its purview—seizures blow the homunculus’s fuses, requiring it to reboot the system and check for damaged files. Same with alcohol, Alzheimer’s disease, a severed spinal cord, hypoglycemic shock. There are domains where the homunculus and that brain biology stuff have worked out a détente—for example, biology is usually automatically regulating your respiration, unless you must take a deep breath before singing an aria, in which case the homunculus briefly overrides the automatic pilot. But other than that, the homunculus makes decisions. Sure, it takes careful note of all the inputs and information from the brain, checks your hormone levels, skims the neurobiology journals, takes it all under advisement, and then, after reflecting and deliberating, decides what you do. A homunculus in your brain, but not of it, operating independently of the material rules of the universe that constitute modern science. That’s what mitigated free will is about. I see incredibly smart people recoil from this and attempt to argue against the extremity of this picture rather than accept its basic validity: “You’re setting up a straw homunculus, suggesting that I think that other than the likes of seizures or brain injuries, we are making all our decisions freely. No, no, my free will is much softer and lurks around the edges of biology, like when I freely decide which socks to wear.” But the frequency or significance with which free will exerts itself doesn’t matter. Even if 99.99 percent of your actions are biologically determined (in the broadest sense of this book), and it is only once a decade that you claim to have chosen out of “free will” to floss your teeth from left to right instead of the reverse, you’ve tacitly invoked a homunculus operating outside the rules of science. This is how most people accommodate the supposed coexistence of free will and biological influences on behavior. For them, nearly all discussions come down to figuring what our putative homunculus should and shouldn’t be expected to be capable of.

Sam’s the man who’s come to chop us up to bits. No wonder I kicked him out. No wonder I changed the locks. If he cannot stop death, what good is he? ‘Open the door. Please. I’m so tired,’ he says. I look at the night that absorbed my life. How am I supposed to know what’s love, what’s fear? ‘If you’re Sam who am I?’ ‘I know who you are.’ ‘You do?’ ‘Yeah.’ ‘Who?’ Don’t say wife, I think. Don’t say mother. I put my face to the glass, but it’s dark. I don’t reflect. Sam and I watch each other through the window of the kitchen door. He coughs some more. ‘I want to come home,’ he says. ‘I want us to be okay. That’s it. Simple. I want to come home and be a family.’ ‘But I am not simple.’ My body’s coursing with secret genes and hormones and proteins. My body made eyeballs and I have no idea how. There’s nothing simple about eyeballs. My body made food to feed those eyeballs. How? And how can I not know or understand the things that happen inside my body? That seems very dangerous. There’s nothing simple here. I’m ruled by elixirs and compounds. I am a chemistry project conducted by a wild child. I am potentially explosive. Maybe I love Sam because hormones say I need a man to kill the coyotes at night, to bring my babies meat. But I don’t want caveman love. I want love that lives outside the body. I want love that lives. ‘In what ways are you not simple?’ I think of the women I collected upstairs. They’re inside me. And they are only a small fraction of the catalog. I think of molds, of the sea, the biodiversity of plankton. I think of my dad when he was a boy, when he was a tree bud. ‘It’s complicated,’ I say, and then the things I don’t say yet. Words aren’t going to be the best way here. How to explain something that’s coming into existence? ‘I get that now.’ His shoulders tremble some. They jerk. He coughs. I have infected him. ‘Sam.’ We see each other through the glass. We witness each other. That’s something, to be seen by another human, to be seen over all the years. That’s something, too. Love plus time. Love that’s movable, invisible as a liquid or gas, love that finds a way in. Love that leaks. ‘Unlock the door,’ he says. ‘I don’t want to love you because I’m scared.’ ‘So you imagine bad things about me. You imagine me doing things I’ve never done to get rid of me. Kick me out so you won’t have to worry about me leaving?’ ‘Yeah,’ I say. ‘Right.’ And I’m glad he gets that. Sam cocks his head the same way a coyote might, a coyote who’s been temporarily confused by a question of biology versus mortality. What’s the difference between living and imagining? What’s the difference between love and security? Coyotes are not moral. ‘Unlock the door?’ he asks. This family is an experiment, the biggest I’ve ever been part of, an experiment called: How do you let someone in? ‘Unlock the door,’ he says again. ‘Please.’ I release the lock. I open the door. That’s the best definition of love. Sam comes inside. He turns to shut the door, then stops himself. He stares out into the darkness where he came from. What does he think is out there? What does he know? Or is he scared I’ll kick him out again? That is scary. ‘What if we just left the door open?’ he asks. ‘Open.’ And more, more things I don’ts say about the bodies of women. ‘Yeah.’ ‘What about skunks?’ I mean burglars, gangs, evil. We both peer out into the dark, looking for thees scary things. We watch a long while. The night does nothing. ‘We could let them in if they want in,’ he says, but seems uncertain still. ‘Really?’ He draws the door open wider and we leave it that way, looking out at what we can’t see. Unguarded, unafraid, love and loved. We keep the door open as if there are no doors, no walls, no skin, no houses, no difference between us and all the things we think of as the night.

The ten rules of ikigai We’ll conclude this journey with ten rules we’ve distilled from the wisdom of the long-living residents of Ogimi: Stay active; don’t retire. Those who give up the things they love doing and do well lose their purpose in life. That’s why it’s so important to keep doing things of value, making progress, bringing beauty or utility to others, helping out, and shaping the world around you, even after your “official” professional activity has ended. Take it slow. Being in a hurry is inversely proportional to quality of life. As the old saying goes, “Walk slowly and you’ll go far.” When we leave urgency behind, life and time take on new meaning. Don’t fill your stomach. Less is more when it comes to eating for long life, too. According to the 80 percent rule, in order to stay healthier longer, we should eat a little less than our hunger demands instead of stuffing ourselves. Surround yourself with good friends. Friends are the best medicine, there for confiding worries over a good chat, sharing stories that brighten your day, getting advice, having fun, dreaming . . . in other words, living. Get in shape for your next birthday. Water moves; it is at its best when it flows fresh and doesn’t stagnate. The body you move through life in needs a bit of daily maintenance to keep it running for a long time. Plus, exercise releases hormones that make us feel happy. Smile. A cheerful attitude is not only relaxing—it also helps make friends. It’s good to recognize the things that aren’t so great, but we should never forget what a privilege it is to be in the here and now in a world so full of possibilities. Reconnect with nature. Though most people live in cities these days, human beings are made to be part of the natural world. We should return to it often to recharge our batteries. Give thanks. To your ancestors, to nature, which provides you with the air you breathe and the food you eat, to your friends and family, to everything that brightens your days and makes you feel lucky to be alive. Spend a moment every day giving thanks, and you’ll watch your stockpile of happiness grow. Live in the moment. Stop regretting the past and fearing the future. Today is all you have. Make the most of it. Make it worth remembering. Follow your ikigai. There is a passion inside you, a unique talent that gives meaning to your days and drives you to share the best of yourself until the very end. If you don’t know what your ikigai is yet, as Viktor Frankl says, your mission is to discover it.

Correlation and causality. Why is it that throughout the animal kingdom and in every human culture, males account for most aggression and violence? Well, what about testosterone and some related hormones, collectively called androgens, a term that unless otherwise noted, I will use simplistically as synonymous with testosterone. In nearly all species, males have more circulating testosterone than do females, who secrete small amounts of androgens from the adrenal glands. Moreover, male aggression is most prevalent when testosterone levels are highest; adolescence and during mating season in seasonal breeders. Thus, testosterone and aggression are linked. Furthermore, there are particularly high levels of testosterone receptors in the amygdala, in the way station by which it projects to the rest of the brain, the bed nucleus of the stria terminalis, and in its major targets, the hypothalamus, the central gray of the mid-brain, and the frontal cortex. But these are merely correlative data. Showing that testosterone causes aggression requires a subtraction plus a replacement experiment. Subtraction, castrate a male: do levels of aggression decrease? Yes, including in humans. This shows that something coming from the testes causes aggression. Is it testosterone? Replacement: give that castrated individual replacement testosterone. Do pre-castration levels of aggression return? Yes, including in humans, thus testosterone causes aggression. Time to see how wrong that is. The first hint of a complication comes after castration. When average levels of aggression plummet in every species, but crucially, not to zero, well, maybe the castration wasn't perfect, you missed some bits of testes, or maybe enough of the minor adrenal androgens are secreted to maintain the aggression. But no, even when testosterone and androgens are completely eliminated, some aggression remains, thus some male aggression is testosterone independent. This point is driven home by castration of some sexual offenders, a legal procedure in a few states. This is accomplished with chemical castration, administration of drugs that either inhibit testosterone production or block testosterone receptors. Castration decreases sexual urges in the subset of sex offenders with intense, obsessive, and pathological urges. But otherwise, castration doesn't decrease recidivism rates as stated in one meta-analysis. Hostile rapists and those who commit sex crimes motivated by power or anger are not amenable to treatment with the anti-androgenic drugs. This leads to a hugely informative point. The more experience the male had being aggressive prior to castration, the more aggression continues afterward. In otherwise, the less his being aggressive in the future requires testosterone and the more it's a function of social learning.

You must develop a symbiotic relationship with everything involved in this program in order to achieve the best results. Of course, you want the perfect butt, a slimmer physique, and a nice tapered waist. But if that’s all you focus on, you become obsessed. Focus on the right things—a strong immune system, balanced hormones, greater confidence, and fewer health issues, and everything else will fall into place.

dairy, because of the fat content, promotes weight gain and colds. That is far from the whole story, though. There is a high correlation between dairy consumption and health concerns. For example, as milk is high in fats consuming them means we spend a high amount of our metabolic energy processing them. This leads to weight gain and means that that energy is not available for muscle building. Also, as mentioned, modern farm animals consume large amounts of medicine, steroids and hormones. These also end up concentrated in the milk and dairy produced by those animals. Then when we consume that dairy they end up in us. There they have the same negative health impact as they do in the animal’s meat. And finally, milk proteins from other animals are not the same as those produced by a human mother. This leads to digestive track inflammation. You might have felt this. It's that bloated feeling you get after having had too much chocolate or milk-based desserts. Our human cells can actually rupture as a result of trying to digest these large cells. And so, milk products have many negative health repercussions. They are therefore best avoided. Instead we should aim for protein sources more aligned with what our bodies need, such as nuts and seeds!

This excessive tiredness can be caused by an overstimulation of adrenal hormones, which are being produced by the body in a state of stress but not being used in the modern office working day. One way to reduce these hormones in the body is to exercise, but most people avoid exercise when they’re feeling exhausted, thinking that they don’t have the energy even to walk to the shop. The reality is that a walk is probably the best thing you can do. Fresh air and exercise can help shift the tiredness rut.

she will be best of both you and me. she will have your strength, your thirst of knowledge your love of sports your giving nature your loving heart your tenderness your ability to dream your creativity your values and mine too She will be the best of both you and me Tireless cycles of ovulation tracking month after month the yogas and the chinese herbs the quigong and the accupuncture the IUIs and the IVFs the hormones and the bloating the mood swing and the heart break when I see the read dot of my period she would have had the best of both you and me the baby we never had ​But I know in my heart She would have had the best of both you and me​

You want to know the best way to keep your hormones balanced? With your diet.

The Republican pirate was charismatic in a way that reached right past all the rightminding safe-guards on my emotions and hormones and made me want to know her better and bond and be best friends with her forever.

Arline Geronimus, a professor at the University of Michigan School of Public Health, provides the best current explanation of how lived experiences can become biology. Her concept of weathering explains that high-effort coping from fighting against racism leads to chronic stress that can trigger premature aging and poor health outcomes. It works this way: stress, the body’s response to a perceived threat, prompts the brain to release hormones, including adrenaline and cortisol. This, in turn, causes blood pressure to increase and the heart rate to speed up. Short, infrequent bursts of this fight-or-flight response are normal, but when it happens again and again, it can turn deadly, eroding health and accelerating aging. Also, as the stressors pile up and feed on each other, they can lead to unhealthy coping mechanisms—drinking, smoking, poor food choices, and drug use. Those who are economically disadvantaged have added stressors in their day-to-day fight for survival, but even educated, well-off African Americans struggle with

So, the liver does its best work cleaning out your body during your deep sleep. This is also when your liver is able to convert your food into energy for your muscles. When the body is full of pollutants, though, your liver never gets to rest and it ends up sending both calories and toxins to your belly fat instead.

Ginseng is one of the best-known herbal tonics.

As soon as possible, following your workout you need to consume: • 30 – 50 grams of a lean complete protein like whey, soy, egg, chicken or fish. • 30 – 50 grams of carbohydrates with a high glycemic index. Why lean protein? Because fat slows the absorption of protein and carbs. During a brief window of opportunity after your workout, protein synthesis occurs at the highest rate. This is due to the micro-trauma (broken-down muscle tissue) that occurred during your workout. Complete recovery will be optimized if you provide your muscles with a large supply of amino acids—the key components of protein—within 45 minutes after your training session. A whey protein shake is the best post-workout protein choice because it is so rapidly absorbed, and it has the highest efficiency ratio, or availability to the body, of all proteins. Why carbs with a high glycemic index? Immediately following your workout is the only time to eat carbs that rapidly absorb into the blood stream as the glucose causes an insulin spike. Insulin helps shuttle protein into the muscles, repairing and building new muscle. It is also an important hormone that regulates the storage, replacement, and use of glucose. During a workout, the body uses stored glucose that is in the blood and muscles as fuel for the activity. If the lost glucose isn’t refilled within about 45 minutes after training, your body rapidly goes from an anabolic state (muscle growth and repair) to a catabolic state (cannibalizing of the body’s muscle for protein and energy). Since insulin signals the body to replenish and store glycogen, and the release of insulin is best triggered by eating foods with a high glycemic index, it makes sense that eating carbohydrates with a high glycemic index, along with some lean protein, is the best post-workout choice. An effective and convenient post workout meal is a whey or soy protein supplement, which contains maltodextrin, or simple sugars, as its carb source.

She’s a hussy and is all like, yes, but they are hot. Bastards. I mean, yes, they are hot. Attractive would be an understatement, they all look like statues of Greek gods. Perfectly carved with abs that don’t come from sitting around all day. They work hard to be the best at everything, and that clearly includes being the best looking. It’s not fair and has my hormones all confused. I hate them, I do. I want to kill them… but also kinda want to screw them? Brilliant.

Many of the most influential of those prewar European authorities had become convinced that obesity must be the result of a hormonal or metabolic dysfunction, not caused by overeating, a concept that they recognized as circular logic. (“To attribute obesity to ‘overeating,’ ” the Harvard nutritionist Jean Mayer had aptly commented eight years before Astwood’s presentation, “is as meaningful as to account for alcoholism by ascribing it to ‘overdrinking.’ ” It’s saying the same thing in two different ways, at best describing the process, not explaining why it’s happening.)

I try at best to be capitalistic but whenever i see the suffering of the unfortunate members of the community,a socialist hormone is induced into my system that whenever i try to balance between the two worlds again i realize i know where i belong,that my identity is not robbed but truly an altruistic African.

I don’t know why we take our worst moods so much more seriously than our best, crediting depression with more clarity than euphoria. We dismiss peak moments and passionate love affairs as an ephemeral chemical buzz, just endorphins or hormones, but accept those 3 A.M. bouts of despair as unsentimental insights into the truth about our lives. It’s easy now to dismiss that year as nothing more

Calories Are Insignificant Compared to Hormones Think about this — if you exercise moderately for 1 hour, you might burn 350 calories. That’s equivalent to several teaspoons of salad dressing. No big deal! The real benefits of exercise occur one to two days later, but only if the environment is almost perfect. In other words, if you do things correctly and don’t violate the fatburning environment, you will burn fat. Fat-storing hormones can easily nullify the fatburning hormones. The worse off your hormone health, the more perfect the other factors need to be. What you eat before, during and after Any carbohydrates (except vegetables) will stimulate insulin, which nullifies the fatburning hormones. This means if you consume sugars 1 hour before or during exercise, you can inhibit the entire purpose of exercise — fat burning. Since fat burning can only occur in the absence of carbohydrates, consuming carbs 14 to 48 hours later can also inhibit fat burning. Drinking several alcoholic beverages can set the liver’s function back for days, preventing fat burning. Protein before workouts is best.2 Eat an egg, some nuts, a small piece of fish or some cheese before exercising. I had a patient who would reward herself for exercising by going to Dairy Queen every day and wondered why she wasn’t losing weight. I had another who would drink half a glass of wine before bed, at the same time working out intensely with no results — I wonder why? Consuming sugar, juice or refined carbohydrates before bed can inhibit fatburning hormones while you sleep. The important thing to remember is that a very small amount of carbohydrates through the day can keep you out of fatburning mode.

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Kerry had headed up the back stairs of the pub, and even as exhausted as she was, she’d still found it impossible to wipe that image of Cooper from her mind. The sun setting over his back, highlighting the breadth of his shoulders, sending shadows under those cheekbones, made more chiseled by the ridiculously gorgeous, shit-eating grin that had been on his face when he made it clear he was in town to stay. “For another twenty-nine days anyway.” Kerry pulled her pillow over her face and groaned. Part of her was still in utter shock that he was actually there, in her town. Hell, in her orbit at all. Other parts of her--most of them hormonally activated--were still all aquiver from that kiss. She groaned again and ground clenched fists into the mattress on either side of her hips. Damn, but that kiss… How many times had she lain in bed, just like this, only in a bunkhouse at Cameroo Downs, and wondered what it would be like to be kissed by Cooper Jax? Okay, okay, a whole lot more than kissed. But damn…that kiss alone had been worlds better than the best sex she’d ever had. So much so, he’d probably ruined her for having sex with mere mortals. So I guess you’ll just have to have sex with him, then. “Not helpful,” she grunted at her little voice, jerking the pillow off her face and thumping it on the bed beside her. Besides, even if she was willing to have some kind of fling with Cooper, fulfill even a sliver of the many, oh, so very many fantasies she’d had about the man, he’d made it clear from pretty much the moment he’d set foot back into her world that he wasn’t looking for a fling. He’d strolled right in and made it clear he was looking for a--no. She squeezed her eyes shut and tightened her lips, willing her mind to go blank. It didn’t work. She couldn’t shut it out. Cooper Jax had, basically, proposed to her. Then he’d walked all up and down a kelp-covered, low-tide seashore and listened to her enumerate the reasons why they couldn’t even contemplate such a union. Right before kissing her in a way that defied science and made her wonder if she might need a pregnancy test, before pretty much declaring he was going to spend the next four weeks making it as impossible for her to say no to his doing that again, and maybe more, as he could.

In short, conventional meat isn’t a woman’s best choice. To find out if meat is making you fat, give it up for three days and see what happens.

resistant fiber Resistant fiber is the new kid on the block. It is a unique type of starch that is digested, but only many hours later and only by the good bacteria. Also known as resistant starch, this fiber contains calories, but the majority of its calories are not usable and therefore cannot cause weight gain. Resistant fiber is remarkable since it creates little or no insulin response, unlike any other carbohydrate. In fact, it can even produce less of an insulin response than many non-carbohydrate foods like meat, poultry, and eggs. For this reason, many of the low-carb breakfasts on the Adrenal Reset Diet include foods high in resistant fiber. BEST SOURCES: Boiled potatoes, cannellini beans, navy beans, great northern beans, and unripe bananas.

If you want to lead a fulfilling and inspiring life, you have to begin by restoring your normal levels of serotonin, dopamine, and cortisol, the three hormones that are most essential to thinking and feeling your best. Making some remarkably simple changes will allow you to rebalance your brain chemistry and tap into your inner reserves of power, joy, and purpose.

Meditation is the best tool for neutralizing the voice in the head. It's a muzzle for the ego. Being mindful is an innate but underused ability we all have, the act of being aware without judging. When you repeatedly go through the cycle of trying to focus on your breath, losing that focus, and noticing and returning to the practice, you are literally building your mindfulness muscle the same way dumbbell curls build your biceps. As this mind-muscle develops, you start being way more aware of thoughts, emotions, and sensations as what they really are: squirts of chemicals & hormones that enter, peak and then fade completely back to the nothingness of which they arose. In other words, mindfulness provides space between impulse and action, so you're not a slave to whatever pops into your head. You are not your thoughts. You are the awareness of them.

Love is just a short-term hormone-driven infatuation, evolved to reinforce the pair bond so that children have the best chance of survival.

It turns out, the morning is actually one of the worst times of the day to drink coffee, according to YouTube science channel ASAP Science. The reason? The high levels of cortisol in our bodies early in the morning. You see, consuming caffeine when cortisol levels are high creates two problems. One is that caffeine interferes with the body’s production of cortisol, a hormone that’s released in response to stress and low blood glucose. The body ends up producing less cortisol, and relying more on caffeine to compensate. The other effect of drinking coffee in the morning is well-known to habitual morning drinkers: It increases the person’s tolerance to caffeine because it replaces the natural cortisol-induced boost instead of adding to it. Bear in mind that cortisol levels are high at three times of the day, not just early in the morning, according to a 2009 study. So the best times to drink coffee — or caffeine in general — is between 10 a.m. and noon, and between 2 p.m. and 5 p.m.

Our eyes and ears can deceive us, our hearts don’t always have the best judgment, and our hormones can lead us astray. But our thoughts are sacred! We have to listen them because they’re the rational part.

Estriol—Estriol is the weakest of the three estrogens and has a protective role in breast tissue. It is believed to protect vaginal tissue too. Estriol helps to reduce hot flashes in women, protects the urinary tract, and plays a role in retention of bone density. It can help increase “good” HDL and decrease “bad” LDL cholesterol. One compelling study showed that taking estriol can reverse brain lesions in women with multiple sclerosis. Estrogen is particularly needed in women to make serotonin function at its best in the brain. Serotonin is one of the brain’s feel-good hormones. With no estrogen, your mood can change to anxious and depressed. Cognitive functions, such as critical thinking and short-term memory, are also eroded with the loss of estrogen production. Below is a list of symptoms related to low and high estrogen levels:

Red Clover Another excellent overall tonic herb, red clover blossoms have a very high vitamin and mineral content, which nourishes the reproductive organs as well as the entire body. This wonderful fertility herb also helps balance hormones for a great boost in your chances of getting pregnant more quickly.

Spirulina is a blue-green algae superfood that is an excellent source of vitamins, minerals, and protein. Spirulina also contains essential fatty acids, which are helpful for balancing hormones and blood pressure.

Milk thistle is a liver-cleansing herb. For fertility, it helps detoxify excess hormones, thus helping to balance hormones.

Dong Quai Another one of the excellent fertility herbs, dong quai specifically helps regulate hormones and tone the uterus. It also helps to maintain estrogen and progesterone balance, which is especially useful for those with estrogen dominance. Also helps with premenstrual depression.

As it stands now we are all told that breastfeeding is the ONLY option for feeding your child, if you actually love that child and ever want them to have more than a third-grade level reading ability. If you don’t breastfeed your baby you might as well just drop it off immediately at your local prison, because that is where it’s going to end up anyway, with such a horrible start to its life. Breastfeeding is beautiful and natural and the best and only socially acceptable way to nourish your baby. It is the most natural thing on the planet, you see. Fast-forward to a severely sleep-deprived, hormone-riddled new mom whose baby is not latching on correctly. If maybe perhaps she had been warned that breastfeeding would not necessarily be easy-peasy, then maybe perhaps she wouldn’t have to add “severe guilt” and “feelings of extreme failure as a woman and mother” to her already long list of postpartum difficulties. So say it with me now: “Breastfeeding is really f’n hard.” Repeat it to yourself, even as you attend classes and read books.

Moreover, it will ensure that fewer doctors will question, for example, gender reassignment surgery or hormone treatment for children, having been further schooled to advance an ideological imperative over the best medical interests of children.

heart rate, breathing, blood pressure, hormones). It takes information from each of your senses – what you can see, hear, touch, taste and smell. It takes information from your actions and thoughts. It pieces all these clues together with memories of when you have felt similar in the past and makes a suggestion, a best guess about what is happening and what you do about it. That guess can sometimes be felt as an emotion or a mood. The meaning we make of that emotion and how we respond to it, in turn, sends information back to the body and the mind about what to do next (Feldman Barrett, 2017). So when it comes to changing your mood, the ingredients that go in will determine what comes out.

Our oath as a Sibyl,” I said, “says never to forget our cruelty, our courage, our ambition. I love that line. Because it reminds me, I’m not looking for favors. I don’t need any of this. Just ignore me. Just let me exist. That’s what I want. Like, all of this here? This makes me a target. This makes my life harder. There are people who want to kill us, Liam. They want us to stop existing. And that is so scary. The government might take me away. But you don’t want to deal with that. Nobody here does. I mention the Governor, and you ignore it. I mention wanting to be on hormones, and you change the subject. Instead, you focus on the Sibyls? That’s so strange! The Sibyls are the best thing about this school, not the worst. If you destroyed the Sibyls, I’d leave this school. If you stopped it being all girls, I’d apologize for ever having wanted to come here. I love this school, and you know why? It’s because of these girls, because they found me. They saw something in me. They’re, like, genuinely good people. Genuinely good friends. They’re like in the Bible, when God said he wouldn’t destroy Sodom if he could find just ten righteous men in it. Antigone and Hecuba and Strife are those men.

Having failed to create societies that our young want to grow into, we idealize the stages of youth. Watching the wide-eyed excitement with which babies face every piece of the world, we envy their openness and naivety, while forgetting the fear and frustration that accompany every bit of progress, from standing upright to drawing a stick-figure. The most pernicious bit of idealization is the very widespread view that the best time of one's life is the decade between sixteen and twenty-six, when young men's muscles and young women's skin are at their most blooming. That's due to hormones, and evolutionary biologists will explain that it happens for a reason. But your goal is not to maximize reproduction, whatever may be said of your genes. By describing what is usually the hardest time of one's life as the best one, we make that time harder for those who are going through it. (If I'm torn and frightened now, what can I expect of the times of my life that, they all tell me, will only get worse?) And that is the point. by describing life as a downhill process, we prepare young people to expect – and demand – very little from it.

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asked if there’s a simple hormone test that can tell if you’re nearing menopause or are already past it. The answer is no. Blood tests can be helpful but are not necessary to diagnose menopause. If you suspect that you’re in perimenopause or want to know if you’re past menopause, the best thing to do is to have a complete medical examination by a qualified healthcare professional. The diagnosis is based on age, medical history, symptoms, and period frequency. Blood work can be used as supportive information, but more often than not, it isn’t needed.

some of the best years of our lives. And guess who gets to decide whether best means dedicating our resources of experience, wisdom, and confidence to others who are younger than us, or celebrating the luxury of being liberated from our periods, or doing a little bit of both? YOU DO. Because whether it’s thanks to evolution or not, you’ve earned it.

Once the mitochondria are functioning at their best and detox pathways are open, genes can be turned off. This is the basis of epigenetics. Our lifestyle influences genes that get turned on, and it also influences genes that get turned off.

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Exercise Remember, high levels of stress are preparing you for a massive physical response: fight or flight. That’s why one of the best treatments for stress is physical exercise. When you move your body vigorously, the stress hormones are absorbed from your blood into your muscles, effectively giving you a substitute for fight or flight. I almost always exercise on the day I’m giving a presentation. Not only do I find myself calmer, but my oxygenated brain also comes up with better ideas more rapidly.

As I will discuss shortly, the body’s resting metabolic rate (RMR) is a key player in our ability to stay lean, and it is affected to a large degree by our body composition with muscle being our greatest calorie burning ally. With that said, it’s important to place the emphasis on a positive change in body composition and not just weight loss. Losing muscle weight is bad and counterproductive. Using the calories in vs. calories out theory alone, can at best give you a temporary fix. It’s unrealistic and unhealthy to go through life following a diet that causes you to feel tired and hungry while your hormones run amuck.

TO HEAL THE GUT, LIGAMENTS, TENDONS, AND SKIN: The peptide BPC-157 may promote speedier recovery from ligament tear reconstruction and rotator cuff tendon injuries. As we’ve already mentioned, this peptide has shown outstanding results in treating debilitating gut problems. I found that out firsthand after my bout with mercury poisoning, which does brutal things to the body. BPC-157 was one of the tools I used to help rebuild my gut, and it was extraordinarily effective. 5. TO INCREASE MUSCLE MASS, STRENGTHEN BONES, REVITALIZE SKIN, AND RESTORE YOUTHFUL METABOLISM: The two peptides sermorelin and tesamorelin mimic the action of growth hormone–releasing hormone (GHRH), a hotbed for new drug development. GHRHs stimulate the pituitary gland to secrete natural growth hormone. They’re a lot cheaper than synthetic human growth hormone (HGH)—and, unlike HGH, can be legally prescribed off-label. What’s the downside? If you take growth hormone or these peptides, you should be aware that growth hormone elevates levels of insulin-like growth factor-1, which has been shown in some studies to have “a modest association” with cancer risk.9 So it’s critical that you work closely with your physician to determine what options are best based on your symptoms, blood work, and careful monitoring.

the pineal located deep in the brain, which secretes the hormone melatonin. Melatonin is best known for synchronizing the activity of our internal organs, including the reproductive organs, with the diurnal and seasonal cycles, but it is also a potent antioxidant that protects the brain and other tissues from damage, so slowing down the aging process.